Harvard Catalyst Profiles

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Maria Concepcion Castells, Ph.D., M.D.

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selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Yang BC, Castells MC. Utilizing Biologics in Drug Desensitization. Curr Allergy Asthma Rep. 2023 Jan; 23(1):1-11. PMID: 36445652; PMCID: PMC9707161.
    Citations:    Fields:    Translation:HumansCells
  2. Novak P, Giannetti MP, Weller E, Hamilton MJ, Mukerji SS, Alabsi HS, Systrom D, Marciano SP, Felsenstein D, Mullally WJ, Pilgrim DM, Castells M. Network autonomic analysis of post-acute sequelae of COVID-19 and postural tachycardia syndrome. Neurol Sci. 2022 Dec; 43(12):6627-6638. PMID: 36169757; PMCID: PMC9517969.
    Citations:    Fields:    Translation:Humans
  3. Dharia T, Lynch DM, Castells MC, Fadugba OO. Endogenous progesterone dermatitis: Successful suppression and desensitization. Ann Allergy Asthma Immunol. 2022 12; 129(6):671-673. PMID: 36084865.
    Citations:    Fields:    Translation:Humans
  4. Pongdee T, Castells M. Elevated Tryptase: Conditions and Pitfalls. J Allergy Clin Immunol Pract. 2022 09; 10(9):2436-2437. PMID: 36087946.
    Citations:    Fields:    Translation:HumansCells
  5. Giannetti MP, Olivieri F, Godwin G, Weller E, Nicoloro-SantaBarbara J, Bonadonna P, Zanotti R, Zanoni G, Hartmann K, Castells M. Outcomes of COVID-19 vaccination in 323 patients with clonal and non-clonal mast cell activation disorders. Allergy. 2023 Jan; 78(1):301-304. PMID: 35962620; PMCID: PMC9538600.
    Citations: 1     Fields:    Translation:HumansCellsPHPublic Health
  6. Mesa RA, Sullivan EM, Dubinski D, Carroll B, Slee VM, Jennings SV, Finnerty CC, Bohannon LS, Mathias SD, Lahue BJ, Castells MC. Perceptions of patient disease burden and management approaches in systemic mastocytosis: Results of the TouchStone Healthcare Provider Survey. Cancer. 2022 10; 128(20):3700-3708. PMID: 35996871; PMCID: PMC9804550.
    Citations:    Fields:    Translation:Humans
  7. Mesa RA, Sullivan EM, Dubinski D, Carroll B, Slee VM, Jennings SV, Finnerty CC, Bohannon LS, Mathias SD, Lahue BJ, Castells MC. Patient-reported outcomes among patients with systemic mastocytosis in routine clinical practice: Results of the TouchStone SM Patient Survey. Cancer. 2022 10; 128(20):3691-3699. PMID: 35996873; PMCID: PMC9804682.
    Citations: 1     Fields:    Translation:Humans
  8. De Campos L, Giavina-Bianchi P, Acharya S, Lynch DM, Kalil J, Castells MC. Basophil Activation Test as a Biomarker for Taxanes Anaphylaxis. Front Allergy. 2022; 3:787749. PMID: 35910859; PMCID: PMC9328177.
    Citations:    
  9. Castells M, Greenhawt M. Vaccination: Just do it! Ann Allergy Asthma Immunol. 2022 07; 129(1):1-2. PMID: 35717128; PMCID: PMC9197789.
    Citations:    Fields:    Translation:HumansPHPublic Health
  10. Pyatilova P, Akin C, Alvarez-Twose I, Arock M, Bonadonna P, Brockow K, Butterfield JH, Broesby-Olsen S, Carter MC, Castells M, George TI, Gotlib J, Greiner G, Gülen T, Hartmann K, Hermine O, Horny HP, Jawhar M, Lange M, Lyons JJ, Maurer M, Metcalfe DD, Nedoszytko B, Niedoszytko M, Orfao A, Reiter A, Schwaab J, Sotlar K, Sperr WR, Triggiani M, Valent P, Siebenhaar F. Refined Treatment Response Criteria for Indolent Systemic Mastocytosis Proposed by the ECNM-AIM Consortium. J Allergy Clin Immunol Pract. 2022 08; 10(8):2015-2024. PMID: 35724950.
    Citations:    Fields:    
  11. Gotlib J, Schwaab J, Shomali W, George TI, Radia DH, Castells M, Carter MC, Hartmann K, Álvarez-Twose I, Brockow K, Bonadonna P, Hermine O, Niedoszytko M, Hoermann G, Sperr WR, Elberink HO, Siebenhaar F, Butterfield JH, Ustun C, Zanotti R, Triggiani M, Schwartz LB, Lyons JJ, Orfao A, Sotlar K, Horny HP, Arock M, Metcalfe DD, Akin C, Lübke J, Valent P, Reiter A. Proposed European Competence Network on Mastocytosis-American Initiative in Mast Cell Diseases (ECNM-AIM) Response Criteria in Advanced Systemic Mastocytosis. J Allergy Clin Immunol Pract. 2022 08; 10(8):2025-2038.e1. PMID: 35724948.
    Citations:    Fields:    
  12. Valent P, Hartmann K, Bonadonna P, Gülen T, Brockow K, Alvarez-Twose I, Hermine O, Niedoszytko M, Carter MC, Hoermann G, Butterfield JH, Lyons JJ, Sperr WR, Greiner G, Sotlar K, Kluin-Nelemans HC, Schwaab J, Lange M, George TI, Siebenhaar F, Broesby-Olsen S, Jawhar M, Nedoszytko B, Castells M, Orfao A, Gotlib J, Reiter A, Horny HP, Triggiani M, Arock M, Metcalfe DD, Akin C. Global Classification of Mast Cell Activation Disorders: An ICD-10-CM-Adjusted Proposal of the ECNM-AIM Consortium. J Allergy Clin Immunol Pract. 2022 08; 10(8):1941-1950. PMID: 35623575.
    Citations:    Fields:    
  13. Giannetti MP, Godwin G, Weller E, Butterfield JH, Castells M. Differential mast cell mediators in systemic mastocytosis and hereditary a-tryptasemia. J Allergy Clin Immunol. 2022 11; 150(5):1225-1227. PMID: 35550148.
    Citations:    Fields:    
  14. Szebeni J, Storm G, Ljubimova JY, Castells M, Phillips EJ, Turjeman K, Barenholz Y, Crommelin DJA, Dobrovolskaia MA. Applying lessons learned from nanomedicines to understand rare hypersensitivity reactions to mRNA-based SARS-CoV-2 vaccines. Nat Nanotechnol. 2022 04; 17(4):337-346. PMID: 35393599.
    Citations: 2     Fields:    Translation:HumansCells
  15. Schaller T, Märkl B, Claus R, Sholl L, Hornick JL, Giannetti MP, Schweizer L, Mann M, Castells M. Mast cells in lung damage of COVID-19 autopsies: A descriptive study. Allergy. 2022 07; 77(7):2237-2239. PMID: 35340030; PMCID: PMC9111237.
    Citations: 1     Fields:    Translation:HumansCells
  16. Yang BC, Castells MC. The Who, What, Where, When, Why, and How of Drug Desensitization. Immunol Allergy Clin North Am. 2022 05; 42(2):403-420. PMID: 35469626.
    Citations:    Fields:    Translation:Humans
  17. Valent P, Hartmann K, Schwaab J, Alvarez-Twose I, Brockow K, Bonadonna P, Hermine O, Niedoszytko M, Carter MC, Hoermann G, Sperr WR, Butterfield JH, Ustun C, Zanotti R, Radia DH, Castells M, Triggiani M, Schwartz LB, Orfao A, George TI, Sotlar K, Gotlib J, Reiter A, Horny HP, Arock M, Akin C, Metcalfe DD. Personalized Management Strategies in Mast Cell Disorders: ECNM-AIM User's Guide for Daily Clinical Practice. J Allergy Clin Immunol Pract. 2022 08; 10(8):1999-2012.e6. PMID: 35342031.
    Citations: 1     Fields:    
  18. Grayson MH, Borish L, Castells MC, Greenhawt MJ, Leung DYM, Lieberman JA, Marshall GD, Nowak-Wegrzyn A, Oppenheimer J, Shaker MS, Shulenberger K, Spergel J, Stukus DR. Annals editors on the war in Ukraine. Ann Allergy Asthma Immunol. 2022 06; 128(6):619-620. PMID: 35342018.
    Citations:    Fields:    Translation:Humans
  19. Bergmann C, Poli A, Agache I, Bianchini R, Bax HJ, Castells M, Crescioli S, Dombrowicz D, Ferastraoaru D, Fiebiger E, Gould HJ, Hartmann K, Izquierdo E, Jordakieva G, Josephs DH, Jutel M, Levi-Schaffer F, de Las Vecillas L, Lotze MT, Osborn G, Pascal M, Redegeld F, Rosenstreich D, Roth-Walter F, Schmidt-Weber C, Shamji M, Steveling EH, Turner MC, Untersmayr E, Jensen-Jarolim E, Karagiannis SN. AllergoOncology: Danger signals in allergology and oncology: A European Academy of Allergy and Clinical Immunology (EAACI) Position Paper. Allergy. 2022 09; 77(9):2594-2617. PMID: 35152450; PMCID: PMC9545837.
    Citations:    Fields:    
  20. Willems SJ, Castells MC, Baptist AP. The Magnification of Health Disparities During the COVID-19 Pandemic. J Allergy Clin Immunol Pract. 2022 04; 10(4):903-908. PMID: 35131511; PMCID: PMC8813673.
    Citations:    Fields:    Translation:HumansCellsPHPublic Health
  21. Dribin TE, Castells M. Anaphylaxis: Data Gaps and Research Needs. Immunol Allergy Clin North Am. 2022 02; 42(1):187-200. PMID: 34823747; PMCID: PMC9210217.
    Citations:    Fields:    Translation:Humans
  22. Castells M, Demoly P, Tanno LK. [Anaphylaxis and COVID-19 vaccines]. Rev Fr Allergol (2009). 2021 Dec; 61(8):8S30-8S35. PMID: 34980951; PMCID: PMC8716577.
    Citations:    
  23. Castells M, Akin C. Finding the right KIT inhibitor for advanced systemic mastocytosis. Nat Med. 2021 12; 27(12):2081-2082. PMID: 34873346.
    Citations:    Fields:    Translation:HumansCells
  24. Pawankar R, Castells M, Akdis M, Nadeau K, Leung ASY. Women in science and medicine. Allergy. 2021 12; 76(12):3578-3580. PMID: 34047393.
    Citations:    Fields:    Translation:Humans
  25. Pagani M, Bavbek S, Alvarez-Cuesta E, Berna Dursun A, Bonadonna P, Castells M, Cernadas J, Chiriac A, Sahar H, Madrigal-Burgaleta R, Sanchez Sanchez S. Hypersensitivity reactions to chemotherapy: an EAACI Position Paper. Allergy. 2022 02; 77(2):388-403. PMID: 34587281.
    Citations: 5     Fields:    Translation:Humans
  26. Valent P, Akin C, Hartmann K, Alvarez-Twose I, Brockow K, Hermine O, Niedoszytko M, Schwaab J, Lyons JJ, Carter MC, Elberink HO, Butterfield JH, George TI, Greiner G, Ustun C, Bonadonna P, Sotlar K, Nilsson G, Jawhar M, Siebenhaar F, Broesby-Olsen S, Yavuz S, Zanotti R, Lange M, Nedoszytko B, Hoermann G, Castells M, Radia DH, Muñoz-Gonzalez JI, Sperr WR, Triggiani M, Kluin-Nelemans HC, Galli SJ, Schwartz LB, Reiter A, Orfao A, Gotlib J, Arock M, Horny HP, Metcalfe DD. Updated Diagnostic Criteria and Classification of Mast Cell Disorders: A Consensus Proposal. Hemasphere. 2021 Nov; 5(11):e646. PMID: 34901755.
    Citations: 4     
  27. Aun MV, Blanca-López N, Castells MC, Giavina-Bianchi P. Editorial: The Role of Mast Cells in Immediate Hypersensitivity Reactions. Front Immunol. 2021; 12:780829. PMID: 34721442; PMCID: PMC8548679.
    Citations:    Fields:    Translation:HumansAnimalsCells
  28. Novak P, Giannetti MP, Weller E, Hamilton MJ, Castells M. Mast cell disorders are associated with decreased cerebral blood flow and small fiber neuropathy. Ann Allergy Asthma Immunol. 2022 03; 128(3):299-306.e1. PMID: 34648976.
    Citations:    Fields:    Translation:HumansCells
  29. Castells MC. Mast cell disorders: A framework of allergy and hematology symptoms leading to personalized treatments. Ann Allergy Asthma Immunol. 2021 10; 127(4):403-404. PMID: 34593102.
    Citations:    Fields:    Translation:HumansCells
  30. Tanno LK, Castells M, Caminati M, Senna G, Demoly P. Anaphylaxis and Coronavirus Disease 2019 vaccine: a danger relationship? Curr Opin Allergy Clin Immunol. 2021 10 01; 21(5):411-417. PMID: 34334663.
    Citations: 2     Fields:    Translation:HumansAnimals
  31. Dribin TE, Schnadower D, Wang J, Camargo CA, Michelson KA, Shaker M, Rudders SA, Vyles D, Golden DBK, Spergel JM, Campbell RL, Neuman MI, Capucilli PS, Pistiner M, Castells M, Lee J, Brousseau DC, Schneider LC, Assa'ad AH, Risma KA, Mistry RD, Campbell DE, Worm M, Turner PJ, Witry JK, Zhang Y, Sobolewski B, Sampson HA. Anaphylaxis knowledge gaps and future research priorities: A consensus report. J Allergy Clin Immunol. 2022 03; 149(3):999-1009. PMID: 34390722; PMCID: PMC8837706.
    Citations: 1     Fields:    Translation:Humans
  32. Carra S, Schatz M, Mertes PM, Torres MJ, Fuchs F, Senna G, Castells MC, Demoly P, Tanno LK. Anaphylaxis and Pregnancy: A Systematic Review and Call for Public Health Actions. J Allergy Clin Immunol Pract. 2021 12; 9(12):4270-4278. PMID: 34365055.
    Citations: 2     Fields:    Translation:HumansPHPublic Health
  33. Tsao LR, Young FD, Otani IM, Castells MC. Hypersensitivity Reactions to Platinum Agents and Taxanes. Clin Rev Allergy Immunol. 2022 Jun; 62(3):432-448. PMID: 34338975; PMCID: PMC9156473.
    Citations: 5     Fields:    Translation:Humans
  34. Bavbek S, Pagani M, Alvarez-Cuesta E, Castells M, Dursun AB, Hamadi S, Madrigal-Burgaleta R, Sanchez-Sanchez S, Vultaggio A. Hypersensitivity reactions to biologicals: An EAACI position paper. Allergy. 2022 01; 77(1):39-54. PMID: 34157134.
    Citations: 3     Fields:    Translation:Humans
  35. Caiado J, Castells MC. Drug Desensitizations for Chemotherapy: Safety and Efficacy in Preventing Anaphylaxis. Curr Allergy Asthma Rep. 2021 07 07; 21(6):37. PMID: 34232411.
    Citations: 4     Fields:    Translation:Humans
  36. Hamilton MJ, Zhao M, Giannetti MP, Weller E, Hufdhi R, Novak P, Mendoza-Alvarez LB, Hornick J, Lyons JJ, Glover SC, Castells MC, Pozdnyakova O. Distinct Small Intestine Mast Cell Histologic Changes in Patients With Hereditary Alpha-tryptasemia and Mast Cell Activation Syndrome. Am J Surg Pathol. 2021 07 01; 45(7):997-1004. PMID: 33481382; PMCID: PMC8192345.
    Citations: 4     Fields:    Translation:HumansCells
  37. Gülen T, Akin C, Bonadonna P, Siebenhaar F, Broesby-Olsen S, Brockow K, Niedoszytko M, Nedoszytko B, Oude Elberink HNG, Butterfield JH, Sperr WR, Alvarez-Twose I, Horny HP, Sotlar K, Schwaab J, Jawhar M, Zanotti R, Nilsson G, Lyons JJ, Carter MC, George TI, Hermine O, Gotlib J, Orfao A, Triggiani M, Reiter A, Hartmann K, Castells M, Arock M, Schwartz LB, Metcalfe DD, Valent P. Selecting the Right Criteria and Proper Classification to Diagnose Mast Cell Activation Syndromes: A Critical Review. J Allergy Clin Immunol Pract. 2021 11; 9(11):3918-3928. PMID: 34166845.
    Citations: 3     Fields:    Translation:HumansCells
  38. Garcia JFB, Aun MV, Motta AA, Castells M, Kalil J, Giavina-Bianchi P. Algorithm to guide re-exposure to penicillin in allergic pregnant women with syphilis: Efficacy and safety. World Allergy Organ J. 2021 Jun; 14(6):100549. PMID: 34093957; PMCID: PMC8165434.
    Citations: 1     
  39. Lee EY, Freedman O, Castells M, Vadas P. Delayed hypersensitivity reactions to multiple aromatase inhibitors followed by successful desensitization to letrozole. Ann Allergy Asthma Immunol. 2021 09; 127(3):378-379. PMID: 34004279.
    Citations:    Fields:    Translation:Humans
  40. Bonamichi-Santos R, Aun MV, Kalil J, Castells MC, Giavina-Bianchi P. PD-L1 Blockade During Allergen Sensitization Inhibits the Synthesis of Specific Antibodies and Decreases Mast Cell Activation in a Murine Model of Active Cutaneous Anaphylaxis. Front Immunol. 2021; 12:655958. PMID: 33968057.
    Citations: 2     Fields:    Translation:AnimalsCellsPHPublic Health
  41. Ebo DG, De Puysseleyr LP, Van Gasse AL, Elst J, Poorten MV, Faber MA, Mertens C, Van Houdt M, Hagendorens MM, Sermeus L, Vitte J, Moise M, Garvey LH, Castells MC, Tacquard C, Mertes PM, Schwartz LB, Sabato V. Mast Cell Activation During Suspected Perioperative Hypersensitivity: A Need for Paired Samples Analysis. J Allergy Clin Immunol Pract. 2021 08; 9(8):3051-3059.e1. PMID: 33862269.
    Citations:    Fields:    Translation:HumansCells
  42. Bonadonna P, Brockow K, Niedoszytko M, Elberink HO, Akin C, Nedoszytko B, Butterfield JH, Alvarez-Twose I, Sotlar K, Schwaab J, Jawhar M, Castells M, Sperr WR, Hermine O, Gotlib J, Zanotti R, Reiter A, Broesby-Olsen S, Bindslev-Jensen C, Schwartz LB, Horny HP, Radia D, Triggiani M, Sabato V, Carter MC, Siebenhaar F, Orfao A, Grattan C, Metcalfe DD, Arock M, Gulen T, Hartmann K, Valent P. COVID-19 Vaccination in Mastocytosis: Recommendations of the European Competence Network on Mastocytosis (ECNM) and American Initiative in Mast Cell Diseases (AIM). J Allergy Clin Immunol Pract. 2021 06; 9(6):2139-2144. PMID: 33831618; PMCID: PMC8019658.
    Citations: 15     Fields:    Translation:HumansCellsPHPublic Health
  43. Blumenthal KG, Castells M, Banerji A. Drug desensitization in the coronavirus disease 2019 pandemic era: Local success to widespread potential. Ann Allergy Asthma Immunol. 2021 06; 126(6):739-741. PMID: 33781932; PMCID: PMC7997944.
    Citations:    Fields:    Translation:HumansCells
  44. Labella M, Castells M. Hypersensitivity reactions and anaphylaxis to checkpoint inhibitor-monoclonal antibodies and desensitization. Ann Allergy Asthma Immunol. 2021 06; 126(6):623-629. PMID: 33781937.
    Citations:    Fields:    Translation:Humans
  45. Vitte J, Sabato V, Tacquard C, Garvey LH, Michel M, Mertes PM, Ebo DG, Schwartz LB, Castells MC. Use and Interpretation of Acute and Baseline Tryptase in Perioperative Hypersensitivity and Anaphylaxis. J Allergy Clin Immunol Pract. 2021 08; 9(8):2994-3005. PMID: 33746087.
    Citations: 4     Fields:    Translation:HumansCells
  46. Zembles T, Mitchell M, Alqurashi W, Castells M, Phillips EJ, Vyles D. Skin Testing for Penicillin Allergy: a Review of the Literature. Curr Allergy Asthma Rep. 2021 03 18; 21(3):21. PMID: 33738621.
    Citations:    Fields:    Translation:Humans
  47. Gotlib J, George TI, Carter MC, Austen KF, Bochner B, Dwyer DF, Lyons JJ, Hamilton MJ, Butterfield J, Bonadonna P, Weiler C, Galli SJ, Schwartz LB, Elberink HO, Maitland A, Theoharides T, Ustun C, Horny HP, Orfao A, Deininger M, Radia D, Jawhar M, Kluin-Nelemans H, Metcalfe DD, Arock M, Sperr WR, Valent P, Castells M, Akin C. Proceedings from the Inaugural American Initiative in Mast Cell Diseases (AIM) Investigator Conference. J Allergy Clin Immunol. 2021 06; 147(6):2043-2052. PMID: 33745886; PMCID: PMC9521380.
    Citations: 2     Fields:    Translation:Humans
  48. Romano A, Broyles AD, Banerji A, Lax T, Torres MJ, Castells M. Reply to "Penilloate and penicilloate concentrations in practical guidance recommendations". J Allergy Clin Immunol Pract. 2021 03; 9(3):1419-1420. PMID: 33685616.
    Citations:    Fields:    Translation:Humans
  49. Giannetti MP, Weller E, Alvarez-Twose I, Torrado I, Bonadonna P, Zanotti R, Dwyer DF, Foer D, Akin C, Hartmann K, Rama TA, Sperr WR, Valent P, Teodosio C, Orfao A, Castells M. COVID-19 infection in patients with mast cell disorders including mastocytosis does not impact mast cell activation symptoms. J Allergy Clin Immunol Pract. 2021 05; 9(5):2083-2086. PMID: 33631409.
    Citations: 5     Fields:    Translation:HumansCells
  50. Bernaola M, Hamadi SA, Lynch DM, Marquis KA, Silver JN, Castells MC, Hsu JT. Successful administration of omalizumab by desensitization protocol following systemic reactions in 12 patients. J Allergy Clin Immunol Pract. 2021 06; 9(6):2505-2508.e1. PMID: 33601048.
    Citations:    Fields:    Translation:Humans
  51. Castells MC, Phillips EJ. Maintaining Safety with SARS-CoV-2 Vaccines. Reply. N Engl J Med. 2021 03 11; 384(10):e37. PMID: 33567190.
    Citations: 7     Fields:    Translation:HumansCells
  52. Rama TA, Moreira A, Castells M. mRNA COVID-19 vaccine is well tolerated in patients with cutaneous and systemic mastocytosis with mast cell activation symptoms and anaphylaxis. J Allergy Clin Immunol. 2021 03; 147(3):877-878. PMID: 33485650; PMCID: PMC7816615.
    Citations: 15     Fields:    Translation:HumansCells
  53. Dribin TE, Schnadower D, Spergel JM, Campbell RL, Shaker M, Neuman MI, Michelson KA, Capucilli PS, Camargo CA, Brousseau DC, Rudders SA, Assa'ad AH, Risma KA, Castells M, Schneider LC, Wang J, Lee J, Mistry RD, Vyles D, Pistiner M, Witry JK, Zhang Y, Sampson HA. Severity grading system for acute allergic reactions: A multidisciplinary Delphi study. J Allergy Clin Immunol. 2021 07; 148(1):173-181. PMID: 33476673; PMCID: PMC8273088.
    Citations: 8     Fields:    Translation:Humans
  54. Giannetti MP, Weller E, Bormans C, Novak P, Hamilton MJ, Castells M. Hereditary alpha-tryptasemia in 101 patients with mast cell activation-related symptomatology including anaphylaxis. Ann Allergy Asthma Immunol. 2021 06; 126(6):655-660. PMID: 33465452.
    Citations: 6     Fields:    Translation:HumansCells
  55. Castells MC, Phillips EJ. Maintaining Safety with SARS-CoV-2 Vaccines. N Engl J Med. 2021 02 18; 384(7):643-649. PMID: 33378605; PMCID: PMC7787218.
    Citations: 120     Fields:    Translation:Humans
  56. Giannetti MP, Akin C, Hufdhi R, Hamilton MJ, Weller E, van Anrooij B, Lyons JJ, Hornick JL, Pinkus G, Castells M, Pozdnyakova O. Patients with mast cell activation symptoms and elevated baseline serum tryptase level have unique bone marrow morphology. J Allergy Clin Immunol. 2021 04; 147(4):1497-1501.e1. PMID: 33248113.
    Citations: 5     Fields:    Translation:HumansCells
  57. Vecillas LL, Castells M. Non-IgE adverse reactions to biologics. J Allergy Clin Immunol. 2021 04; 147(4):1204-1206. PMID: 33227316.
    Citations: 1     Fields:    Translation:HumansAnimals
  58. Jakubovic BD, Sanchez-Sanchez S, Hamadi S, Lynch DM, Castells M. Interleukin-6: A novel biomarker for monoclonal antibody and chemotherapy-associated hypersensitivity confirms a cytokine release syndrome phenotype-endotype association. Allergy. 2021 05; 76(5):1571-1573. PMID: 33119137.
    Citations: 3     Fields:    Translation:Humans
  59. Tang MM, Fok JS, Thong BY, Yun J, Li PH, Kang HR, Thien F, Yamaguchi M, Lucas M, Chang YS, Kim BK, Nagao M, Rengganis I, Tsai YG, Chung WH, Rerkpattanapipat T, Kamchaisatian W, Leung TF, Ho JY, Zhang L, Latiff AHA, Fujisawa T, Castells MC, Demoly P, Wang JY, Pawankar R. Diagnostic procedures & practices in drug allergy/hypersensitivity: a survey of 13 Asian countries. Asia Pac Allergy. 2020 Oct; 10(4):e36. PMID: 33178561; PMCID: PMC7610088.
    Citations: 2     
  60. Broyles AD, Banerji A, Barmettler S, Biggs CM, Blumenthal K, Brennan PJ, Breslow RG, Brockow K, Buchheit KM, Cahill KN, Cernadas J, Chiriac AM, Crestani E, Demoly P, Dewachter P, Dilley M, Farmer JR, Foer D, Fried AJ, Garon SL, Giannetti MP, Hepner DL, Hong DI, Hsu JT, Kothari PH, Kyin T, Lax T, Lee MJ, Lee-Sarwar K, Liu A, Logsdon S, Louisias M, MacGinnitie A, Maciag M, Minnicozzi S, Norton AE, Otani IM, Park M, Patil S, Phillips EJ, Picard M, Platt CD, Rachid R, Rodriguez T, Romano A, Stone CA, Torres MJ, Verdú M, Wang AL, Wickner P, Wolfson AR, Wong JT, Yee C, Zhou J, Castells M. Practical Guidance for the Evaluation and Management of Drug Hypersensitivity: Specific Drugs. J Allergy Clin Immunol Pract. 2020 10; 8(9S):S16-S116. PMID: 33039007.
    Citations: 28     Fields:    Translation:Humans
  61. Senna G, Caminati M, Castells M. Editorial: Reconsidering anaphylaxis at the time of COVID-19 pandemic. Curr Opin Allergy Clin Immunol. 2020 10; 20(5):429-430. PMID: 32739982.
    Citations:    Fields:    Translation:HumansCellsPHPublic Health
  62. Foer D, Tran LK, Wickner P, Castells M, Marquis KA, Buchheit KM. Challenges in skin testing for progestogen hypersensitivity. Ann Allergy Asthma Immunol. 2021 01; 126(1):100-102. PMID: 32911056.
    Citations:    Fields:    Translation:Humans
  63. Dribin TE, Sampson HA, Camargo CA, Brousseau DC, Spergel JM, Neuman MI, Shaker M, Campbell RL, Michelson KA, Rudders SA, Assa'ad AH, Risma KA, Castells M, Schneider LC, Wang J, Lee J, Mistry RD, Vyles D, Vaughn LM, Schumacher DJ, Witry JK, Viswanathan S, Page EM, Schnadower D. Persistent, refractory, and biphasic anaphylaxis: A multidisciplinary Delphi study. J Allergy Clin Immunol. 2020 11; 146(5):1089-1096. PMID: 32853640; PMCID: PMC8006564.
    Citations: 8     Fields:    Translation:Humans
  64. Hong DI, Madrigal-Burgaleta R, Banerji A, Castells M, Alvarez-Cuesta E. Controversies in Allergy: Chemotherapy Reactions, Desensitize, or Delabel? J Allergy Clin Immunol Pract. 2020 10; 8(9):2907-2915.e1. PMID: 32805455.
    Citations: 5     Fields:    Translation:Humans
  65. Broyles AD, Banerji A, Castells M. Practical Guidance for the Evaluation and Management of Drug Hypersensitivity: General Concepts. J Allergy Clin Immunol Pract. 2020 10; 8(9S):S3-S15. PMID: 32791249.
    Citations: 13     Fields:    Translation:Humans
  66. Ferastraoaru D, Bax HJ, Bergmann C, Capron M, Castells M, Dombrowicz D, Fiebiger E, Gould HJ, Hartmann K, Jappe U, Jordakieva G, Josephs DH, Levi-Schaffer F, Mahler V, Poli A, Rosenstreich D, Roth-Walter F, Shamji M, Steveling-Klein EH, Turner MC, Untersmayr E, Karagiannis SN, Jensen-Jarolim E. AllergoOncology: ultra-low IgE, a potential novel biomarker in cancer-a Position Paper of the European Academy of Allergy and Clinical Immunology (EAACI). Clin Transl Allergy. 2020; 10:32. PMID: 32695309; PMCID: PMC7366896.
    Citations: 12     
  67. Yang BC, Castells M. Medical algorithm: Diagnosis and treatment of drug hypersensitivity reactions to biologicals. Allergy. 2020 12; 75(12):3293-3296. PMID: 32496608.
    Citations: 5     Fields:    Translation:Humans
  68. Valent P, Akin C, Bonadonna P, Brockow K, Niedoszytko M, Nedoszytko B, Butterfield JH, Alvarez-Twose I, Sotlar K, Schwaab J, Jawhar M, Reiter A, Castells M, Sperr WR, Kluin-Nelemans HC, Hermine O, Gotlib J, Zanotti R, Broesby-Olsen S, Horny HP, Triggiani M, Siebenhaar F, Orfao A, Metcalfe DD, Arock M, Hartmann K. Risk and management of patients with mastocytosis and MCAS in the SARS-CoV-2 (COVID-19) pandemic: Expert opinions. J Allergy Clin Immunol. 2020 08; 146(2):300-306. PMID: 32561389; PMCID: PMC7297685.
    Citations: 8     Fields:    Translation:HumansCellsPHPublic Health
  69. Castells MC. Drug allergy labeling and delabeling in the coronavirus disease 2019 era: What is important and what do we need to know. Ann Allergy Asthma Immunol. 2020 06; 124(6):523-525. PMID: 32448437.
    Citations: 1     Fields:    Translation:HumansCellsPHPublic Health
  70. Otani IM, Castells M. Novel Roles for Platinum and Taxane Agent Skin Testing in Risk Stratification of Chemotherapy Hypersensitivity. J Allergy Clin Immunol Pract. 2020 05; 8(5):1665-1667. PMID: 32389278.
    Citations:    Fields:    Translation:Humans
  71. Caiado J, Brás R, Paulino M, Costa L, Castells M. Rapid desensitization to antineoplastic drugs in an outpatient immunoallergology clinic: Outcomes and risk factors. Ann Allergy Asthma Immunol. 2020 09; 125(3):325-333.e1. PMID: 32353405.
    Citations: 6     Fields:    Translation:Humans
  72. Jakubovic BD, Vecillas LL, Jimenez-Rodriguez TW, Sanchez-Sanchez S, Castells M. Drug hypersensitivity in the fast lane: What clinicians should know about phenotypes, endotypes, and biomarkers. Ann Allergy Asthma Immunol. 2020 06; 124(6):566-572. PMID: 32302769.
    Citations: 4     Fields:    Translation:HumansCells
  73. Castells M, Khan DA, Phillips EJ. Penicillin Allergy. Reply. N Engl J Med. 2020 04 02; 382(14):1380. PMID: 32242379.
    Citations: 1     Fields:    Translation:Humans
  74. Giannetti MP, Akin C, Castells M. Idiopathic Anaphylaxis: A Form of Mast Cell Activation Syndrome. J Allergy Clin Immunol Pract. 2020 04; 8(4):1196-1201. PMID: 32276688.
    Citations: 5     Fields:    Translation:HumansCells
  75. Castells MC, Li JT. Anaphylaxis: Parts Unknown. J Allergy Clin Immunol Pract. 2020 04; 8(4):1216-1218. PMID: 32276690.
    Citations:    Fields:    Translation:Humans
  76. Moñino-Romero S, Vecillas LL, Alenazy LA, Labella M, Szépfalusi Z, Fiebiger E, Castells MC. Soluble FceRI, IgE, and tryptase as potential biomarkers of rapid desensitizations for platin IgE sensitized cancer patients. J Allergy Clin Immunol Pract. 2020 06; 8(6):2085-2088.e10. PMID: 32028011; PMCID: PMC9012077.
    Citations: 4     Fields:    Translation:Humans
  77. Castells MC. Anaphylaxis: watch out, it is everywhere now! Ann Allergy Asthma Immunol. 2020 02; 124(2):116-117. PMID: 32029208.
    Citations:    Fields:    Translation:Humans
  78. Thong BY, Lucas M, Kang HR, Chang YS, Li PH, Tang MM, Yun J, Fok JS, Kim BK, Nagao M, Rengganis I, Tsai YG, Chung WH, Yamaguchi M, Rerkpattanapipat T, Kamchaisatian W, Leung TF, Yoon HJ, Zhang L, Latiff AHA, Fujisawa T, Thien F, Castells MC, Demoly P, Wang JY, Pawankar R. Drug hypersensitivity reactions in Asia: regional issues and challenges. Asia Pac Allergy. 2020 Jan; 10(1):e8. PMID: 32099830; PMCID: PMC7016324.
    Citations: 3     
  79. Castells M, Khan DA, Phillips EJ. Penicillin Allergy. N Engl J Med. 2019 12 12; 381(24):2338-2351. PMID: 31826341.
    Citations: 26     Fields:    Translation:Humans
  80. Giannetti M, Silver J, Hufdhi R, Castells M. One-day ultrarush desensitization for Hymenoptera venom anaphylaxis in patients with and without mast cell disorders with adjuvant omalizumab. J Allergy Clin Immunol Pract. 2020 Apr; 8(4):1431-1435.e3. PMID: 31704439.
    Citations: 2     Fields:    Translation:HumansAnimalsCells
  81. Castells M. Go, ladies, go: The goal is ahead! J Allergy Clin Immunol. 2019 12; 144(6):1518-1520. PMID: 31639384.
    Citations:    Fields:    Translation:Humans
  82. Vyles D, Chiu A, Routes J, Castells M, Phillips EJ, Visotcky A, Fraser R, Pezzin L, Brousseau DC. Oral amoxicillin challenges in low-risk children during a pediatric emergency department visit. J Allergy Clin Immunol Pract. 2020 03; 8(3):1126-1128.e1. PMID: 31586667.
    Citations: 6     Fields:    Translation:Humans
  83. Senna G, Caminati M, Castells M. Editorial: Anaphylaxis: advances and challenges besides allergy. Curr Opin Allergy Clin Immunol. 2019 10; 19(5):415-416. PMID: 31369415.
    Citations: 2     Fields:    Translation:HumansAnimalsCells
  84. Carter MC, Akin C, Castells MC, Scott EP, Lieberman P. Idiopathic anaphylaxis yardstick: Practical recommendations for clinical practice. Ann Allergy Asthma Immunol. 2020 01; 124(1):16-27. PMID: 31513910.
    Citations: 4     Fields:    Translation:Humans
  85. Khan DA, Banerji A, Bernstein JA, Bilgicer B, Blumenthal K, Castells M, Ein D, Lang DM, Phillips E. Cephalosporin Allergy: Current Understanding and Future Challenges. J Allergy Clin Immunol Pract. 2019 Sep - Oct; 7(7):2105-2114. PMID: 31495420; PMCID: PMC6955146.
    Citations: 16     Fields:    Translation:Humans
  86. Jakubovic BD, Jagdis A, Trinkaus M, Lang A, Chang A, Rastin T, Castells M, Betschel S. Recurrent neurologic symptoms complicating venom immunotherapy in a patient with systemic mastocytosis and severe Hymenoptera allergy. J Allergy Clin Immunol Pract. 2020 Feb; 8(2):780-782. PMID: 31415904.
    Citations:    Fields:    Translation:HumansAnimals
  87. Castells M. Drug allergy: Veni, vidi, vici-come, understand, and delabel, avoid, or desensitize. Ann Allergy Asthma Immunol. 2019 07; 123(1):1-2. PMID: 31255190.
    Citations: 1     Fields:    Translation:Humans
  88. Castells M. Race and allergy: Are we that different? Ann Allergy Asthma Immunol. 2019 05; 122(5):439-440. PMID: 31054648.
    Citations:    Fields:    Translation:Humans
  89. Gupta M, Akin C, Sanders GM, Chan MP, Ross CW, Castells MC. Blisters, Vaccines, and Mast Cells: A Difficult Case of Diffuse Cutaneous Mastocytosis. J Allergy Clin Immunol Pract. 2019 04; 7(4):1370-1372. PMID: 30961844.
    Citations: 2     Fields:    Translation:HumansCellsPHPublic Health
  90. Castells M, Butterfield J. Mast Cell Activation Syndrome and Mastocytosis: Initial Treatment Options and Long-Term Management. J Allergy Clin Immunol Pract. 2019 04; 7(4):1097-1106. PMID: 30961835.
    Citations: 21     Fields:    Translation:Humans
  91. Grayson MH, Oppenheimer J, Castells M, Nowak-Wegrzyn A. Life-long learning and the American Board of Allergy and Immunology: Practice improvement comes of age. Ann Allergy Asthma Immunol. 2019 07; 123(1):6-8. PMID: 30910438.
    Citations:    Fields:    Translation:Humans
  92. Yang BC, Castells MC. Rituximab hypersensitivity and desensitization: a personalized approach to treat cancer and connective tissue diseases. Ann Allergy Asthma Immunol. 2019 07; 123(1):11-15. PMID: 30885801.
    Citations: 3     Fields:    Translation:Humans
  93. Foer D, Marquis K, Romero N, Castells MC. Challenges and safety of beta-lactam desensitization during extracorporeal membrane oxygenation. Ann Allergy Asthma Immunol. 2019 06; 122(6):661-663. PMID: 30878628; PMCID: PMC6555662.
    Citations:    Fields:    Translation:Humans
  94. Campos L, Galvão VR, Kalil J, Castells M, Giavina-Bianchi P. BAT in the Diagnosis of Drug Allergy: a Novel Tool in Clinical Daily Practice? Curr Allergy Asthma Rep. 2019 03 11; 19(4):20. PMID: 30859323.
    Citations: 2     Fields:    Translation:HumansCells
  95. Giavina-Bianchi P, Gonçalves DG, Zanandréa A, Borges de Castro R, Garro LS, Kalil J, Castells M. Anaphylaxis to quinolones in mastocytosis: Hypothesis on the mechanism. J Allergy Clin Immunol Pract. 2019 Jul - Aug; 7(6):2089-2090. PMID: 30797080.
    Citations: 6     Fields:    Translation:HumansAnimals
  96. Nowak-Wegrzyn A, Ellis A, Castells M. Sex and allergic diseases. Ann Allergy Asthma Immunol. 2019 02; 122(2):134-135. PMID: 30711034.
    Citations: 3     Fields:    Translation:Humans
  97. Deak PE, Kim B, Adnan A, Labella M, De Las Vecillas L, Castells M, Bilgicer B. Nanoallergen platform for detection of platin drug allergies. J Allergy Clin Immunol. 2019 05; 143(5):1957-1960.e12. PMID: 30682456; PMCID: PMC6608568.
    Citations: 4     Fields:    Translation:HumansCells
  98. Castells MC. Capturing Drug-Induced Anaphylaxis Through Electronic Health Records: A Step Forward. J Allergy Clin Immunol Pract. 2019 01; 7(1):112-113. PMID: 30598173.
    Citations: 1     Fields:    Translation:Humans
  99. Demoly P, Castells M. Important questions in drug allergy and hypersensitivity: consensus papers from the 2018 AAAAI/WAO international drug allergy symposium. World Allergy Organ J. 2018; 11(1):42. PMID: 30598723; PMCID: PMC6299668.
    Citations: 1     
  100. Carter MC, Metcalfe DD, Matito A, Escribano L, Butterfield JH, Schwartz LB, Bonadonna P, Zanotti R, Triggiani M, Castells M, Brockow K. Adverse reactions to drugs and biologics in patients with clonal mast cell disorders: A Work Group Report of the Mast Cells Disorder Committee, American Academy of Allergy, Asthma & Immunology. J Allergy Clin Immunol. 2019 03; 143(3):880-893. PMID: 30528617.
    Citations: 16     Fields:    Translation:HumansAnimals
  101. Gotlib J, Gerds AT, Bose P, Castells MC, Deininger MW, Gojo I, Gundabolu K, Hobbs G, Jamieson C, McMahon B, Mohan SR, Oehler V, Oh S, Padron E, Pancari P, Papadantonakis N, Pardanani A, Podoltsev N, Rampal R, Ranheim E, Rein L, Snyder DS, Stein BL, Talpaz M, Thota S, Wadleigh M, Walsh K, Bergman MA, Sundar H. Systemic Mastocytosis, Version 2.2019, NCCN Clinical Practice Guidelines in Oncology. J Natl Compr Canc Netw. 2018 12; 16(12):1500-1537. PMID: 30545997.
    Citations: 6     Fields:    Translation:HumansCells
  102. Castells M. New role for the modern allergist in drug allergy: Assess, diagnose, and de-label. Ann Allergy Asthma Immunol. 2018 11; 121(5):515-516. PMID: 30389081.
    Citations: 1     Fields:    Translation:Humans
  103. Desai M, Castells M. Anaphylactic shock to bacitracin irrigation during breast implant surgery. Ann Allergy Asthma Immunol. 2019 02; 122(2):217-218. PMID: 30347235.
    Citations:    Fields:    Translation:Humans
  104. Pagani M, Bavbek S, Dursun AB, Bonadonna P, Caralli M, Cernadas J, Cortellini G, Costantino MT, Gelincik A, Lucchini G, Castells M. Role of Skin Tests in the Diagnosis of Immediate Hypersensitivity Reactions to Taxanes: Results of a Multicenter Study. J Allergy Clin Immunol Pract. 2019 03; 7(3):990-997. PMID: 30292919.
    Citations: 4     Fields:    Translation:Humans
  105. Ben-Ami E, Castells MC, Connell NT, Rutherford AE, Thornton KA. Imatinib-induced drug reaction with eosinophilia and systemic symptoms in solid tumors: a patient with dermatofibrosarcoma protuberans and successful desensitization management. Anticancer Drugs. 2018 10; 29(9):919-923. PMID: 30096127.
    Citations: 3     Fields:    Translation:Humans
  106. Russell N, Jennings S, Jennings B, Slee V, Sterling L, Castells M, Valent P, Akin C. The Mastocytosis Society Survey on Mast Cell Disorders: Part 2-Patient Clinical Experiences and Beyond. J Allergy Clin Immunol Pract. 2019 04; 7(4):1157-1165.e6. PMID: 30098409.
    Citations: 3     Fields:    Translation:Humans
  107. Jennings SV, Slee VM, Zack RM, Verstovsek S, George TI, Shi H, Lee P, Castells MC. Patient Perceptions in Mast Cell Disorders. Immunol Allergy Clin North Am. 2018 08; 38(3):505-525. PMID: 30007467.
    Citations: 5     Fields:    Translation:HumansCells
  108. Otani IM, Carroll RW, Yager P, Kroshinsky D, Murphy S, Hornick JL, Akin C, Castells M, Walter JE. Diffuse cutaneous mastocytosis with novel somatic KIT mutation K509I and association with tuberous sclerosis. Clin Case Rep. 2018 Sep; 6(9):1834-1840. PMID: 30214774; PMCID: PMC6132108.
    Citations: 2     
  109. Ornelas C, Caiado J, Campos Melo A, Pereira Barbosa M, Castells MC, Pereira Dos Santos MC. The Contribution of the Basophil Activation Test to the Diagnosis of Hypersensitivity Reactions to Oxaliplatin. Int Arch Allergy Immunol. 2018; 177(3):274-280. PMID: 30041169.
    Citations: 4     Fields:    Translation:HumansCells
  110. Jimenez-Rodriguez TW, Garcia-Neuer M, Alenazy LA, Castells M. Anaphylaxis in the 21st century: phenotypes, endotypes, and biomarkers. J Asthma Allergy. 2018; 11:121-142. PMID: 29950872; PMCID: PMC6016596.
    Citations: 27     
  111. Valent P, Akin C, Bonadonna P, Hartmann K, Broesby-Olsen S, Brockow K, Butterfield JH, Reiter A, Gotlib J, Castells M, Milner JD, Carter MC, Komarow H, Radia D, Pardanani A, Sotlar K, Triggiani M, Horny HP, Arock M, Schwartz LB, Metcalfe DD. Mast cell activation syndrome: Importance of consensus criteria and call for research. J Allergy Clin Immunol. 2018 09; 142(3):1008-1010. PMID: 29928922; PMCID: PMC7115848.
    Citations: 6     Fields:    Translation:Humans