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Maria Concepcion Castells, Ph.D., M.D.

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Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Senna G, Caminati M, Castells M. Reconsidering anaphylaxis at the time of COVID-19 pandemic. Curr Opin Allergy Clin Immunol. 2020 Jul 27. PMID: 32739982.
    Citations:    
  2. Ferastraoaru D, Bax HJ, Bergmann C, Capron M, Castells M, Dombrowicz D, Fiebiger E, Gould HJ, Hartmann K, Jappe U, Jordakieva G, Josephs DH, Levi-Schaffer F, Mahler V, Poli A, Rosenstreich D, Roth-Walter F, Shamji M, Steveling-Klein EH, Turner MC, Untersmayr E, Karagiannis SN, Jensen-Jarolim E. AllergoOncology: ultra-low IgE, a potential novel biomarker in cancer-a Position Paper of the European Academy of Allergy and Clinical Immunology (EAACI). Clin Transl Allergy. 2020; 10:32. PMID: 32695309.
    Citations:    
  3. Valent P, Akin C, Bonadonna P, Brockow K, Niedoszytko M, Nedoszytko B, Butterfield JH, Alvarez-Twose I, Sotlar K, Schwaab J, Jawhar M, Reiter A, Castells M, Sperr WR, Kluin-Nelemans HC, Hermine O, Gotlib J, Zanotti R, Broesby-Olsen S, Horny HP, Triggiani M, Siebenhaar F, Orfao A, Metcalfe DD, Arock M, Hartmann K. Risk and management of patients with mastocytosis and MCAS in the SARS-CoV-2 (COVID-19) pandemic: Expert opinions. J Allergy Clin Immunol. 2020 Aug; 146(2):300-306. PMID: 32561389.
    Citations:    
  4. Yang BC, Castells M. Diagnosis and treatment of drug hypersensitivity reactions to biologicals: Medical algorithm. Allergy. 2020 Jun 04. PMID: 32496608.
    Citations:    
  5. Castells MC. Drug allergy labeling and delabeling in the coronavirus disease 2019 era: What is important and what do we need to know. Ann Allergy Asthma Immunol. 2020 06; 124(6):523-525. PMID: 32448437.
    Citations:    
  6. Otani IM, Castells M. Novel Roles for Platinum and Taxane Agent Skin Testing in Risk Stratification of Chemotherapy Hypersensitivity. J Allergy Clin Immunol Pract. 2020 May; 8(5):1665-1667. PMID: 32389278.
    Citations:    
  7. Caiado J, Brás R, Paulino M, Costa L, Castells M. Rapid desensitization to antineoplastic drugs in an outpatient immunoallergology clinic: Outcomes and risk factors. Ann Allergy Asthma Immunol. 2020 Apr 27. PMID: 32353405.
    Citations:    
  8. Jakubovic BD, Vecillas LL, Jimenez-Rodriguez TW, Sanchez-Sanchez S, Castells M. Drug hypersensitivity in the fast lane: What clinicians should know about phenotypes, endotypes, and biomarkers. Ann Allergy Asthma Immunol. 2020 06; 124(6):566-572. PMID: 32302769.
    Citations:    
  9. Castells M, Khan DA, Phillips EJ. Penicillin Allergy. Reply. N Engl J Med. 2020 04 02; 382(14):1380. PMID: 32242379.
    Citations:    
  10. Castells MC, Li JT. Anaphylaxis: Parts Unknown. J Allergy Clin Immunol Pract. 2020 Apr; 8(4):1216-1218. PMID: 32276690.
    Citations:    
  11. Giannetti MP, Akin C, Castells M. Idiopathic Anaphylaxis: A Form of Mast Cell Activation Syndrome. J Allergy Clin Immunol Pract. 2020 Apr; 8(4):1196-1201. PMID: 32276688.
    Citations:    
  12. Moñino-Romero S, Vecillas LL, Alenazy LA, Labella M, Szépfalusi Z, Fiebiger E, Castells MC. Soluble FceRI, IgE, and tryptase as potential biomarkers of rapid desensitizations for platin IgE sensitized cancer patients. J Allergy Clin Immunol Pract. 2020 Jun; 8(6):2085-2088.e10. PMID: 32028011.
    Citations:    
  13. Castells MC. Anaphylaxis: watch out, it is everywhere now! Ann Allergy Asthma Immunol. 2020 02; 124(2):116-117. PMID: 32029208.
    Citations:    
  14. Thong BY, Lucas M, Kang HR, Chang YS, Li PH, Tang MM, Yun J, Fok JS, Kim BK, Nagao M, Rengganis I, Tsai YG, Chung WH, Yamaguchi M, Rerkpattanapipat T, Kamchaisatian W, Leung TF, Yoon HJ, Zhang L, Latiff AHA, Fujisawa T, Thien F, Castells MC, Demoly P, Wang JY, Pawankar R. Drug hypersensitivity reactions in Asia: regional issues and challenges. Asia Pac Allergy. 2020 Jan; 10(1):e8. PMID: 32099830.
    Citations:    
  15. Castells M, Khan DA, Phillips EJ. Penicillin Allergy. N Engl J Med. 2019 12 12; 381(24):2338-2351. PMID: 31826341.
    Citations:    
  16. Giannetti M, Silver J, Hufdhi R, Castells M. One-day ultrarush desensitization for Hymenoptera venom anaphylaxis in patients with and without mast cell disorders with adjuvant omalizumab. J Allergy Clin Immunol Pract. 2020 Apr; 8(4):1431-1435.e3. PMID: 31704439.
    Citations:    
  17. Castells M. Go, ladies, go: The goal is ahead! J Allergy Clin Immunol. 2019 12; 144(6):1518-1520. PMID: 31639384.
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  18. Vyles D, Chiu A, Routes J, Castells M, Phillips EJ, Visotcky A, Fraser R, Pezzin L, Brousseau DC. Oral amoxicillin challenges in low-risk children during a pediatric emergency department visit. J Allergy Clin Immunol Pract. 2020 Mar; 8(3):1126-1128.e1. PMID: 31586667.
    Citations:    
  19. Senna G, Caminati M, Castells M. Editorial: Anaphylaxis: advances and challenges besides allergy. Curr Opin Allergy Clin Immunol. 2019 10; 19(5):415-416. PMID: 31369415.
    Citations:    
  20. Carter MC, Akin C, Castells MC, Scott EP, Lieberman P. Idiopathic anaphylaxis yardstick: Practical recommendations for clinical practice. Ann Allergy Asthma Immunol. 2020 01; 124(1):16-27. PMID: 31513910.
    Citations:    
  21. Khan DA, Banerji A, Bernstein JA, Bilgicer B, Blumenthal K, Castells M, Ein D, Lang DM, Phillips E. Cephalosporin Allergy: Current Understanding and Future Challenges. J Allergy Clin Immunol Pract. 2019 Sep - Oct; 7(7):2105-2114. PMID: 31495420.
    Citations:    
  22. Jakubovic BD, Jagdis A, Trinkaus M, Lang A, Chang A, Rastin T, Castells M, Betschel S. Recurrent neurologic symptoms complicating venom immunotherapy in a patient with systemic mastocytosis and severe Hymenoptera allergy. J Allergy Clin Immunol Pract. 2020 Feb; 8(2):780-782. PMID: 31415904.
    Citations:    
  23. Castells M. Drug allergy: Veni, vidi, vici-come, understand, and delabel, avoid, or desensitize. Ann Allergy Asthma Immunol. 2019 07; 123(1):1-2. PMID: 31255190.
    Citations:    
  24. Castells M. Race and allergy: Are we that different? Ann Allergy Asthma Immunol. 2019 05; 122(5):439-440. PMID: 31054648.
    Citations:    
  25. Gupta M, Akin C, Sanders GM, Chan MP, Ross CW, Castells MC. Blisters, Vaccines, and Mast Cells: A Difficult Case of Diffuse Cutaneous Mastocytosis. J Allergy Clin Immunol Pract. 2019 04; 7(4):1370-1372. PMID: 30961844.
    Citations:    
  26. Castells M, Butterfield J. Mast Cell Activation Syndrome and Mastocytosis: Initial Treatment Options and Long-Term Management. J Allergy Clin Immunol Pract. 2019 04; 7(4):1097-1106. PMID: 30961835.
    Citations:    
  27. Grayson MH, Oppenheimer J, Castells M, Nowak-Wegrzyn A. Life-long learning and the American Board of Allergy and Immunology: Practice improvement comes of age. Ann Allergy Asthma Immunol. 2019 07; 123(1):6-8. PMID: 30910438.
    Citations:    
  28. Yang BC, Castells MC. Rituximab hypersensitivity and desensitization: a personalized approach to treat cancer and connective tissue diseases. Ann Allergy Asthma Immunol. 2019 07; 123(1):11-15. PMID: 30885801.
    Citations:    
  29. Foer D, Marquis K, Romero N, Castells MC. Challenges and safety of beta-lactam desensitization during extracorporeal membrane oxygenation. Ann Allergy Asthma Immunol. 2019 06; 122(6):661-663. PMID: 30878628.
    Citations:    
  30. Campos L, Galvão VR, Kalil J, Castells M, Giavina-Bianchi P. BAT in the Diagnosis of Drug Allergy: a Novel Tool in Clinical Daily Practice? Curr Allergy Asthma Rep. 2019 03 11; 19(4):20. PMID: 30859323.
    Citations:    
  31. Giavina-Bianchi P, Gonçalves DG, Zanandréa A, Borges de Castro R, Garro LS, Kalil J, Castells M. Anaphylaxis to quinolones in mastocytosis: Hypothesis on the mechanism. J Allergy Clin Immunol Pract. 2019 Jul - Aug; 7(6):2089-2090. PMID: 30797080.
    Citations:    
  32. Nowak-Wegrzyn A, Ellis A, Castells M. Sex and allergic diseases. Ann Allergy Asthma Immunol. 2019 02; 122(2):134-135. PMID: 30711034.
    Citations:    
  33. Deak PE, Kim B, Adnan A, Labella M, De Las Vecillas L, Castells M, Bilgicer B. Nanoallergen platform for detection of platin drug allergies. J Allergy Clin Immunol. 2019 05; 143(5):1957-1960.e12. PMID: 30682456.
    Citations:    Fields:    
  34. Castells MC. Capturing Drug-Induced Anaphylaxis Through Electronic Health Records: A Step Forward. J Allergy Clin Immunol Pract. 2019 01; 7(1):112-113. PMID: 30598173.
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  35. Demoly P, Castells M. Important questions in drug allergy and hypersensitivity: consensus papers from the 2018 AAAAI/WAO international drug allergy symposium. World Allergy Organ J. 2018; 11(1):42. PMID: 30598723.
    Citations:    
  36. Carter MC, Metcalfe DD, Matito A, Escribano L, Butterfield JH, Schwartz LB, Bonadonna P, Zanotti R, Triggiani M, Castells M, Brockow K. Adverse reactions to drugs and biologics in patients with clonal mast cell disorders: A Work Group Report of the Mast Cells Disorder Committee, American Academy of Allergy, Asthma & Immunology. J Allergy Clin Immunol. 2019 03; 143(3):880-893. PMID: 30528617.
    Citations:    Fields:    
  37. Gotlib J, Gerds AT, Bose P, Castells MC, Deininger MW, Gojo I, Gundabolu K, Hobbs G, Jamieson C, McMahon B, Mohan SR, Oehler V, Oh S, Padron E, Pancari P, Papadantonakis N, Pardanani A, Podoltsev N, Rampal R, Ranheim E, Rein L, Snyder DS, Stein BL, Talpaz M, Thota S, Wadleigh M, Walsh K, Bergman MA, Sundar H. Systemic Mastocytosis, Version 2.2019, NCCN Clinical Practice Guidelines in Oncology. J Natl Compr Canc Netw. 2018 12; 16(12):1500-1537. PMID: 30545997.
    Citations:    Fields:    
  38. Castells M. New role for the modern allergist in drug allergy: Assess, diagnose, and de-label. Ann Allergy Asthma Immunol. 2018 11; 121(5):515-516. PMID: 30389081.
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  39. Desai M, Castells M. Anaphylactic shock to bacitracin irrigation during breast implant surgery. Ann Allergy Asthma Immunol. 2019 02; 122(2):217-218. PMID: 30347235.
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  40. Pagani M, Bavbek S, Dursun AB, Bonadonna P, Caralli M, Cernadas J, Cortellini G, Costantino MT, Gelincik A, Lucchini G, Castells M. Role of Skin Tests in the Diagnosis of Immediate Hypersensitivity Reactions to Taxanes: Results of a Multicenter Study. J Allergy Clin Immunol Pract. 2019 03; 7(3):990-997. PMID: 30292919.
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  41. Ben-Ami E, Castells MC, Connell NT, Rutherford AE, Thornton KA. Imatinib-induced drug reaction with eosinophilia and systemic symptoms in solid tumors: a patient with dermatofibrosarcoma protuberans and successful desensitization management. Anticancer Drugs. 2018 10; 29(9):919-923. PMID: 30096127.
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  42. Russell N, Jennings S, Jennings B, Slee V, Sterling L, Castells M, Valent P, Akin C. The Mastocytosis Society Survey on Mast Cell Disorders: Part 2-Patient Clinical Experiences and Beyond. J Allergy Clin Immunol Pract. 2019 04; 7(4):1157-1165.e6. PMID: 30098409.
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  43. Jennings SV, Slee VM, Zack RM, Verstovsek S, George TI, Shi H, Lee P, Castells MC. Patient Perceptions in Mast Cell Disorders. Immunol Allergy Clin North Am. 2018 08; 38(3):505-525. PMID: 30007467.
    Citations:    Fields:    Translation:HumansCells
  44. Otani IM, Carroll RW, Yager P, Kroshinsky D, Murphy S, Hornick JL, Akin C, Castells M, Walter JE. Diffuse cutaneous mastocytosis with novel somatic KIT mutation K509I and association with tuberous sclerosis. Clin Case Rep. 2018 Sep; 6(9):1834-1840. PMID: 30214774.
    Citations:    
  45. Ornelas C, Caiado J, Campos Melo A, Pereira Barbosa M, Castells MC, Pereira Dos Santos MC. The Contribution of the Basophil Activation Test to the Diagnosis of Hypersensitivity Reactions to Oxaliplatin. Int Arch Allergy Immunol. 2018; 177(3):274-280. PMID: 30041169.
    Citations:    Fields:    Translation:HumansCells
  46. Jimenez-Rodriguez TW, Garcia-Neuer M, Alenazy LA, Castells M. Anaphylaxis in the 21st century: phenotypes, endotypes, and biomarkers. J Asthma Allergy. 2018; 11:121-142. PMID: 29950872.
    Citations: 1     
  47. Valent P, Akin C, Bonadonna P, Hartmann K, Broesby-Olsen S, Brockow K, Butterfield JH, Reiter A, Gotlib J, Castells M, Milner JD, Carter MC, Komarow H, Radia D, Pardanani A, Sotlar K, Triggiani M, Horny HP, Arock M, Schwartz LB, Metcalfe DD. Mast cell activation syndrome: Importance of consensus criteria and call for research. J Allergy Clin Immunol. 2018 09; 142(3):1008-1010. PMID: 29928922.
    Citations:    Fields:    
  48. Castells MC. Mastocytosis: Moving the Field to Precision and Personalized Medicine. Immunol Allergy Clin North Am. 2018 08; 38(3):xv-xvii. PMID: 30007470.
    Citations:    Fields:    Translation:HumansAnimalsCells
  49. Labella M, Garcia-Neuer M, Castells M. Application of precision medicine to the treatment of anaphylaxis. Curr Opin Allergy Clin Immunol. 2018 06; 18(3):190-197. PMID: 29601357.
    Citations:    Fields:    
  50. Bonamichi-Santos R, Castells M. Diagnoses and Management of Drug Hypersensitivity and Anaphylaxis in Cancer and Chronic Inflammatory Diseases: Reactions to Taxanes and Monoclonal Antibodies. Clin Rev Allergy Immunol. 2018 Jun; 54(3):375-385. PMID: 27277133.
    Citations: 3     Fields:    Translation:Humans
  51. Garro LS, Aun MV, Soares ISC, Ribeiro MR, Motta AA, Kalil J, Castells MC, Carmona MJC, Giavina-Bianchi P. Specific questionnaire detects a high incidence of intra-operative hypersensitivity reactions. Clinics (Sao Paulo). 2018 05 17; 73:e287. PMID: 29791521.
    Citations:    Fields:    Translation:Humans
  52. Vyles D, Chiu A, Routes J, Castells M, Phillips EJ, Kibicho J, Brousseau DC. Antibiotic Use After Removal of Penicillin Allergy Label. Pediatrics. 2018 05; 141(5). PMID: 29678929.
    Citations: 1     Fields:    
  53. Isabwe GAC, Garcia Neuer M, de Las Vecillas Sanchez L, Lynch DM, Marquis K, Castells M. Hypersensitivity reactions to therapeutic monoclonal antibodies: Phenotypes and endotypes. J Allergy Clin Immunol. 2018 07; 142(1):159-170.e2. PMID: 29518427.
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  54. Tanno LK, Torres MJ, Castells M, Demoly P. What can we learn in drug allergy management from World Health Organization's international classifications? Allergy. 2018 05; 73(5):987-992. PMID: 29105793.
    Citations:    
  55. Traina G, Valluzzi RL, Fierro V, Riccardi C, Artesani MC, De Vuono A, Fiocchi A, Martelli AG, Ríos LA, Alcocer CR, Navarrete E, Del Rio Navarro BE, Gonzalez V, Velasco B, Perez Aviles HJ, Fernandez RJ, Pozo FC, Farhan AJ, Arshad H, Hussain A, Sharikadze O, Okhotnikova O, Alcover J, Rodriguez D, Pineda F, Dalal I, Weinbrand-Goichberg J, Benor S, Rottem M, Kivity S, Sato S, Yanagida N, Ebisawa M, Umanets T, Pineda F, Antipkin Y, Barzylovich V, Lapshyn V, Umanets T, Umanets M, Yuriev S, Pineda F, Rodriguez D, Alcover J, Bekir S, Pincock T, Vieira Hernandez A, Capriles Hulett A, Sánchez Borges M, Fabiano F, Albarran C, Goyal R, Gupta S, Gaurav G, Luskin AT, Griffin NM, Wagelie-Steffen A, Trzaskoma BL, Limb SL, Busse WW, Zeiger RS, Gonzalez-Reyes E, Casale TB, Chipps BE, Sugizaki C, Goto F, Sato S, Yanagida N, Ebisawa M, Yamaide A, Mitsunaga K, Tomiita M, Hoshioka A, Shimojo N, Pop LL, Ciuca IM, Tamas L, Lazarescu M, Pienar C, Yamaide F, Fikri B, Sato H, Shimojo N, Okishima N, Kobayashi M, Takai M, Nishigata K, Yoda R, Oana YT, Kajiwara C, Shimodaira M, Suzuki T, Iizawa H, Kamijo K, Karmakar B, Bhattacharya SG, Blohlávková S, Kopelentová E, Víšek P, Štádler J, Šetinová I, Novobílská J, Lundelin K, Salminen S, Isolauri E, Pitt T, Flanders T, Peñalver M, Martínez P, Lluch M, Malet A, Nam YH, Jin HJ, Lee SK, Kulalert P, Sritipsukho P, Pathumanond J, Baynova K, Labella M, De Aramburu T, Prados M, Haanpää L, Aarnio J, Nermes M, Af Ursin P, Kaljonen A, Isolauri E, Bala N, Bhagwat K, Hindley J, Chapman M, Baalasubramanian S, Besednjak-Kocijancic L, SenGupta K, Bhattacharya SG, Chipps BE, Antonova E, Kong AM, Iqbal A, Teague WG, Chipps BE, Antonova E, Trzaskoma B, Ortiz B, Paknis B, Iqbal A, Rosen K, Szefler S, Alblooshi A, Al-Hammadi S, Vega A, Gutiérrez-Rivas R, Alonso AM, Beitia JM, Belén Mateo M, Cárdenas R, García-Domínguez JJ, Pitchon Dos Reis R, Gonçalves Alvim C, Andrade C, Reis A, Ribeiro H, Panaitescu Bunu C, Marusciac L, Paralescu S, Tamas P, Panitescu Bunu C, Marusciac L, Paralescu S, Tamas P, Martí Guadaño E, Escobar Bolaños C, Martí José N, Pau Casanovas P, Biarnés Rib G, Castells M, de Vicente Jiménez T, Mennini M, Riccardi C, De Angelis P, Rea F, Malamisura M, Tambucci R, Fiocchi A, Dall'Oglio L, Mennini M, Del Chierico F, Napolitano T, Reddel S, Vernocchi P, D'Ambrosio A, Putignani L, Artesani MC, Dahdah L, Fierro V, Banzato C, Echeverría Zudaire LA, Plaza AM, Bosque García M, Íbero M, Mazzina O, Fierro V, Marzano V, Riccardi C, Mazzina O, Dahdah L, Mennini M, Artesani MC, Mazzina O, Pecora V, Koch P, Valluzzi RL, Fierro V, Fiocchi A, Pecora V, Valentini D, Mennini M, Dahdah L, Mazzina O, Santamaria F, Valluzzi R, Mukherjee A, Kandhare A, Bodhankar S. Proceedings of the 2017 WAO Symposium on Hot Topics in Allergy: Pediatric & Regulatory Aspects: Rome, Italy/Vatican City. 27-29 April 2017. World Allergy Organ J. 2017; 10(Suppl 2):39. PMID: 29444193.
    Citations:    
  56. Castells M. Drug Hypersensitivity and Anaphylaxis in Cancer and Chronic Inflammatory Diseases: The Role of Desensitizations. Front Immunol. 2017; 8:1472. PMID: 29163536.
    Citations:    
  57. Castells MC. Drug Hypersensitivity and Desensitizations. Immunol Allergy Clin North Am. 2017 11; 37(4):xvii-xviii. PMID: 28965644.
    Citations:    Fields:    Translation:Humans
  58. Isabwe GAC, de Las Vecillas Sanchez L, Castells M. Management of adverse reactions to biologic agents. Allergy Asthma Proc. 2017 Nov 01; 38(6):409-418. PMID: 29046192.
    Citations: 1     Fields:    Translation:Humans
  59. Garcia-Neuer M, Lynch DM, Marquis K, Dowdall J, Castells M, Sloane DE. Drug-Induced Paradoxical Vocal Fold Motion. J Allergy Clin Immunol Pract. 2018 Jan - Feb; 6(1):90-94. PMID: 29037819.
    Citations:    Fields:    
  60. Castells MC. Invited Commentary: Mast Cell Activation. Curr Allergy Asthma Rep. 2017 09 27; 17(10):73. PMID: 28956253.
    Citations:    Fields:    
  61. Castells M. Diagnosis and management of anaphylaxis in precision medicine. J Allergy Clin Immunol. 2017 Aug; 140(2):321-333. PMID: 28780940.
    Citations: 6     Fields:    Translation:HumansAnimals
  62. de Las Vecillas Sánchez L, Alenazy LA, Garcia-Neuer M, Castells MC. Drug Hypersensitivity and Desensitizations: Mechanisms and New Approaches. Int J Mol Sci. 2017 Jun 20; 18(6). PMID: 28632196.
    Citations: 1     Fields:    Translation:HumansCells
  63. Prieto-García A, Pérez-David E, Devesa C, Tornero P, Schwartz LB, Pascual C, Castells MC. Fatal anaphylaxis caused by gadolinium due to beta-tryptase-induced hemorragic diathesis. J Allergy Clin Immunol Pract. 2017 Sep - Oct; 5(5):1433-1434. PMID: 28634099.
    Citations:    Fields:    
  64. Mendonca LO, Malle L, Donovan FX, Chandrasekharappa SC, Montealegre Sanchez GA, Garg M, Tedgard U, Castells M, Saini SS, Dutta S, Goldbach-Mansky R, Suri D, Jesus AA. Deficiency of Interleukin-1 Receptor Antagonist (DIRA): Report of the First Indian Patient and a Novel Deletion Affecting IL1RN. J Clin Immunol. 2017 Jul; 37(5):445-451. PMID: 28503715.
    Citations: 1     Fields:    Translation:Humans
  65. Castells MC. Drug Allergy: Phenotypes, Endotypes, and Biomarkers. J Allergy Clin Immunol Pract. 2017 May - Jun; 5(3):626-627. PMID: 28483316.
    Citations:    Fields:    
  66. Muraro A, Lemanske RF, Castells M, Torres MJ, Khan D, Simon HU, Bindslev-Jensen C, Burks W, Poulsen LK, Sampson HA, Worm M, Nadeau KC. Precision medicine in allergic disease-food allergy, drug allergy, and anaphylaxis-PRACTALL document of the European Academy of Allergy and Clinical Immunology and the American Academy of Allergy, Asthma and Immunology. Allergy. 2017 Jul; 72(7):1006-1021. PMID: 28122115.
    Citations: 10     Fields:    Translation:Humans
  67. Torres MJ, Romano A, Celik G, Demoly P, Khan DA, Macy E, Park M, Blumenthal K, Aberer W, Castells M, Barbaud A, Mayorga C, Bonadonna P. Approach to the diagnosis of drug hypersensitivity reactions: similarities and differences between Europe and North America. Clin Transl Allergy. 2017; 7:7. PMID: 28293415.
    Citations: 6     
  68. Macy E, Khan DA, Castells MC, Lang DM. Penicillin Allergy Testing: A Key Component of Antibiotic Stewardship. Clin Infect Dis. 2017 02 15; 64(4):531-532. PMID: 28174914.
    Citations: 2     Fields:    Translation:Humans
  69. Jensen-Jarolim E, Bax HJ, Bianchini R, Capron M, Corrigan C, Castells M, Dombrowicz D, Daniels-Wells TR, Fazekas J, Fiebiger E, Gatault S, Gould HJ, Janda J, Josephs DH, Karagiannis P, Levi-Schaffer F, Meshcheryakova A, Mechtcheriakova D, Mekori Y, Mungenast F, Nigro EA, Penichet ML, Redegeld F, Saul L, Singer J, Spicer JF, Siccardi AG, Spillner E, Turner MC, Untersmayr E, Vangelista L, Karagiannis SN. AllergoOncology - the impact of allergy in oncology: EAACI position paper. Allergy. 2017 Jun; 72(6):866-887. PMID: 28032353.
    Citations: 3     Fields:    Translation:HumansCells
  70. Kowalski ML, Ansotegui I, Aberer W, Al-Ahmad M, Akdis M, Ballmer-Weber BK, Beyer K, Blanca M, Brown S, Bunnag C, Hulett AC, Castells M, Chng HH, De Blay F, Ebisawa M, Fineman S, Golden DB, Haahtela T, Kaliner M, Katelaris C, Lee BW, Makowska J, Muller U, Mullol J, Oppenheimer J, Park HS, Parkerson J, Passalacqua G, Pawankar R, Renz H, Rueff F, Sanchez-Borges M, Sastre J, Scadding G, Sicherer S, Tantilipikorn P, Tracy J, van Kampen V, Bohle B, Canonica GW, Caraballo L, Gomez M, Ito K, Jensen-Jarolim E, Larche M, Melioli G, Poulsen LK, Valenta R, Zuberbier T. Erratum to: Risk and safety requirements for diagnostic and therapeutic procedures in allergology: World Allergy Organization Statement. World Allergy Organ J. 2017; 10(1):6. PMID: 28101294.
    Citations:    
  71. Giavina-Bianchi P, Galvão VR, Picard M, Caiado J, Castells MC. Basophil Activation Test is a Relevant Biomarker of the Outcome of Rapid Desensitization in Platinum Compounds-Allergy. J Allergy Clin Immunol Pract. 2017 May - Jun; 5(3):728-736. PMID: 28034549.
    Citations: 4     Fields:    Translation:HumansCells
  72. Macy E, Khan DA, Castells MC, Lang DM. Penicillin Allergy Testing, A Key Component of Antibiotic Stewardship. Clin Infect Dis. 2016 Dec 07. PMID: 27927854.
    Citations:    
  73. Galvão VR, Phillips E, Giavina-Bianchi P, Castells MC. Carboplatin-allergic patients undergoing desensitization: prevalence and impact of the BRCA 1/2 mutation. J Allergy Clin Immunol Pract. 2017 May - Jun; 5(3):816-818. PMID: 27765459.
    Citations: 2     Fields:    
  74. Kowalski ML, Ansotegui I, Aberer W, Al-Ahmad M, Akdis M, Ballmer-Weber BK, Beyer K, Blanca M, Brown S, Bunnag C, Hulett AC, Castells M, Chng HH, De Blay F, Ebisawa M, Fineman S, Golden DB, Haahtela T, Kaliner M, Katelaris C, Lee BW, Makowska J, Muller U, Mullol J, Oppenheimer J, Park HS, Parkerson J, Passalacqua G, Pawankar R, Renz H, Rueff F, Sanchez-Borges M, Sastre J, Scadding G, Sicherer S, Tantilipikorn P, Tracy J, van Kempen V, Bohle B, Canonica GW, Caraballo L, Gomez M, Ito K, Jensen-Jarolim E, Larche M, Melioli G, Poulsen LK, Valenta R, Zuberbier T. Risk and safety requirements for diagnostic and therapeutic procedures in allergology: World Allergy Organization Statement. World Allergy Organ J. 2016; 9(1):33. PMID: 27777642.
    Citations: 7     
  75. Cingi C, Wallace D, Bayar Muluk N, Ebisawa M, Castells M, Sahin E, Altintoprak N. Managing anaphylaxis in the office setting. Am J Rhinol Allergy. 2016 Jul; 30(4):118-23. PMID: 27456586.
    Citations:    Fields:    Translation:Humans
  76. Foer D, Buchheit KM, Gargiulo AR, Lynch DM, Castells M, Wickner PG. Progestogen Hypersensitivity in 24 Cases: Diagnosis, Management, and Proposed Renaming and Classification. J Allergy Clin Immunol Pract. 2016 Jul-Aug; 4(4):723-9. PMID: 27090357.
    Citations: 4     Fields:    Translation:Humans
  77. Sloane D, Govindarajulu U, Harrow-Mortelliti J, Barry W, Hsu FI, Hong D, Laidlaw T, Palis R, Legere H, Bunyavanich S, Breslow R, Wesemann D, Barrett N, Brennan P, Chong HJ, Liu A, Fernandez J, Fanning L, Kyin T, Cahill K, Bankova L, Lynch A, Berlin S, Campos S, Fuchs C, Mayer R, Matulonis U, Castells M. Safety, Costs, and Efficacy of Rapid Drug Desensitizations to Chemotherapy and Monoclonal Antibodies. J Allergy Clin Immunol Pract. 2016 May-Jun; 4(3):497-504. PMID: 26895621.
    Citations: 5     Fields:    Translation:Humans
  78. Ganetsky A, Takach PA, Lynch DM, Krause TM, Teh JS, Stadtmauer EA, Castells M, Weiss BM. Melphalan desensitization following immediate hypersensitivity in a patient undergoing conditioning for autologous hematopoietic cell transplantation. J Allergy Clin Immunol Pract. 2016 May-Jun; 4(3):555-6. PMID: 26883541.
    Citations:    Fields:    Translation:Humans
  79. Bonamichi-Santos R, Castells M. Desensitization for Drug Hypersensitivity to Chemotherapy and Monoclonal Antibodies. Curr Pharm Des. 2016; 22(45):6870-6880. PMID: 27784245.
    Citations:    Fields:    Translation:Humans
  80. Castells MC, Bankova L. Reply. J Allergy Clin Immunol Pract. 2016 Jan-Feb; 4(1):190-1. PMID: 26772937.
    Citations:    Fields:    Translation:HumansPHPublic Health
  81. González-de-Olano D, Morgado JM, Juárez-Guerrero R, Sánchez-Muñoz L, Letellez-Fernández J, Malón-Giménez D, Castells MC. Positive basophil activation test following anaphylaxis to pertuzumab and successful treatment with rapid desensitization. J Allergy Clin Immunol Pract. 2016 Mar-Apr; 4(2):338-40. PMID: 26725157.
    Citations:    Fields:    Translation:HumansCells
  82. Picard M, Pur L, Caiado J, Giavina-Bianchi P, Galvão VR, Berlin ST, Campos SM, Matulonis UA, Castells MC. Risk stratification and skin testing to guide re-exposure in taxane-induced hypersensitivity reactions. J Allergy Clin Immunol. 2016 Apr; 137(4):1154-1164.e12. PMID: 26725998.
    Citations: 3     Fields:    Translation:Humans
  83. Hartmann K, Escribano L, Grattan C, Brockow K, Carter MC, Alvarez-Twose I, Matito A, Broesby-Olsen S, Siebenhaar F, Lange M, Niedoszytko M, Castells M, Oude Elberink JNG, Bonadonna P, Zanotti R, Hornick JL, Torrelo A, Grabbe J, Rabenhorst A, Nedoszytko B, Butterfield JH, Gotlib J, Reiter A, Radia D, Hermine O, Sotlar K, George TI, Kristensen TK, Kluin-Nelemans HC, Yavuz S, Hägglund H, Sperr WR, Schwartz LB, Triggiani M, Maurer M, Nilsson G, Horny HP, Arock M, Orfao A, Metcalfe DD, Akin C, Valent P. Cutaneous manifestations in patients with mastocytosis: Consensus report of the European Competence Network on Mastocytosis; the American Academy of Allergy, Asthma & Immunology; and the European Academy of Allergology and Clinical Immunology. J Allergy Clin Immunol. 2016 Jan; 137(1):35-45. PMID: 26476479.
    Citations: 16     Fields:    Translation:Humans
  84. Picard M, Castells MC. Re-visiting Hypersensitivity Reactions to Taxanes: A Comprehensive Review. Clin Rev Allergy Immunol. 2015 Oct; 49(2):177-91. PMID: 24740483.
    Citations: 8     Fields:    Translation:HumansAnimals
  85. Wheatley LM, Plaut M, Schwaninger JM, Banerji A, Castells M, Finkelman FD, Gleich GJ, Guttman-Yassky E, Mallal SA, Naisbitt DJ, Ostrov DA, Phillips EJ, Pichler WJ, Platts-Mills TA, Roujeau JC, Schwartz LB, Trepanier LA. Report from the National Institute of Allergy and Infectious Diseases workshop on drug allergy. J Allergy Clin Immunol. 2015 Aug; 136(2):262-71.e2. PMID: 26254053.
    Citations: 7     Fields:    Translation:Humans
  86. Castells MC. A New Era for Drug Desensitizations. J Allergy Clin Immunol Pract. 2015 Jul-Aug; 3(4):639-40. PMID: 26164579.
    Citations: 2     Fields:    Translation:HumansAnimals
  87. Giavina-Bianchi P, Aun MV, Motta AA, Kalil J, Castells M. Classification of angioedema by endotypes. Clin Exp Allergy. 2015 Jun; 45(6):1142-3. PMID: 25981351.
    Citations: 1     Fields:    Translation:Humans
  88. Castells MC. Anaphylaxis to chemotherapy and monoclonal antibodies. Immunol Allergy Clin North Am. 2015 May; 35(2):335-48. PMID: 25841555.
    Citations: 2     Fields:    Translation:Humans
  89. Castells MC, Hornick JL, Akin C. Anaphylaxis after hymenoptera sting: is it venom allergy, a clonal disorder, or both? J Allergy Clin Immunol Pract. 2015 May-Jun; 3(3):350-5. PMID: 25858055.
    Citations: 2     Fields:    Translation:HumansAnimals
  90. Caiado J, Castells M. Presentation and Diagnosis of Hypersensitivity to Platinum Drugs. Curr Allergy Asthma Rep. 2015 Apr; 15(4):15. PMID: 26130472.
    Citations:    
  91. Galvão VR, Castells MC. Hypersensitivity to biological agents-updated diagnosis, management, and treatment. J Allergy Clin Immunol Pract. 2015 Mar-Apr; 3(2):175-85; quiz 186. PMID: 25754718.
    Citations: 11     Fields:    Translation:Humans
  92. Bavbek S, Ataman S, Akinci A, Castells M. Rapid subcutaneous desensitization for the management of local and systemic hypersensitivity reactions to etanercept and adalimumab in 12 patients. J Allergy Clin Immunol Pract. 2015 Jul-Aug; 3(4):629-32. PMID: 25725941.
    Citations: 1     Fields:    Translation:Humans
  93. Aun MV, Blanca M, Garro LS, Ribeiro MR, Kalil J, Motta AA, Castells M, Giavina-Bianchi P. Reply: To PMID 25017529. J Allergy Clin Immunol Pract. 2014 Nov-Dec; 2(6):826. PMID: 25439389.
    Citations:    Fields:    Translation:Humans
  94. Park MA, Solensky R, Khan DA, Castells MC, Macy EM, Lang DM. Patients with positive skin test results to penicillin should not undergo penicillin or amoxicillin challenge. J Allergy Clin Immunol. 2015 Mar; 135(3):816-7. PMID: 25441646.
    Citations: 1     Fields:    Translation:Humans
  95. Crestani E, Lee J, Gorman M, Castells M, Dioun Broyles AF. IgE-mediated hypersensitivity reaction and desensitization to glatiramer acetate in a pediatric patient. Pediatr Allergy Immunol. 2014 Dec; 25(8):821-3. PMID: 25200765.
    Citations:    Fields:    Translation:Humans
  96. Galvão VR, Giavina-Bianchi P, Castells M. Perioperative anaphylaxis. Curr Allergy Asthma Rep. 2014 Aug; 14(8):452. PMID: 24951238.
    Citations: 7     Fields:    Translation:Humans
  97. Hsu Blatman KS, Castells MC. Desensitizations for chemotherapy and monoclonal antibodies: indications and outcomes. Curr Allergy Asthma Rep. 2014 Aug; 14(8):453. PMID: 24994467.
    Citations: 7     Fields:    Translation:Humans
  98. Vultaggio A, Castells MC. Hypersensitivity reactions to biologic agents. Immunol Allergy Clin North Am. 2014 Aug; 34(3):615-32, ix. PMID: 25017680.
    Citations: 8     Fields:    Translation:Humans
  99. Ensina LF, Aranda CS, de Lacerda AE, Camelo-Nunes I, Sole D, Martins AM, Castells M. Laronidase hypersensitivity and desensitization in type I mucopolysaccharidosis: a case report. Pediatr Allergy Immunol. 2014 Aug; 25(5):498-9. PMID: 25313426.
    Citations:    Fields:    Translation:Humans
  100. Doyle LA, Sepehr GJ, Hamilton MJ, Akin C, Castells MC, Hornick JL. A clinicopathologic study of 24 cases of systemic mastocytosis involving the gastrointestinal tract and assessment of mucosal mast cell density in irritable bowel syndrome and asymptomatic patients. Am J Surg Pathol. 2014 Jun; 38(6):832-43. PMID: 24618605.
    Citations: 8     Fields:    Translation:HumansCells
  101. Aun MV, Blanca M, Garro LS, Ribeiro MR, Kalil J, Motta AA, Castells M, Giavina-Bianchi P. Nonsteroidal anti-inflammatory drugs are major causes of drug-induced anaphylaxis. J Allergy Clin Immunol Pract. 2014 Jul-Aug; 2(4):414-20. PMID: 25017529.
    Citations: 11     Fields:    Translation:Humans
  102. Valent P, Escribano L, Broesby-Olsen S, Hartmann K, Grattan C, Brockow K, Niedoszytko M, Nedoszytko B, Oude Elberink JN, Kristensen T, Butterfield JH, Triggiani M, Alvarez-Twose I, Reiter A, Sperr WR, Sotlar K, Yavuz S, Kluin-Nelemans HC, Hermine O, Radia D, van Doormaal JJ, Gotlib J, Orfao A, Siebenhaar F, Schwartz LB, Castells M, Maurer M, Horny HP, Akin C, Metcalfe DD, Arock M. Proposed diagnostic algorithm for patients with suspected mastocytosis: a proposal of the European Competence Network on Mastocytosis. Allergy. 2014 Oct; 69(10):1267-74. PMID: 24836395.
    Citations: 13     Fields:    Translation:Humans
  103. Lee MJ, Wickner P, Fanning L, Schlossman R, Richardson P, Laubach J, Castells M. Lenalidomide desensitization for delayed hypersensitivity reactions in 5 patients with multiple myeloma. Br J Haematol. 2014 Oct; 167(1):127-31. PMID: 24824093.
    Citations: 2     Fields:    Translation:Humans
  104. Demoly P, Adkinson NF, Brockow K, Castells M, Chiriac AM, Greenberger PA, Khan DA, Lang DM, Park HS, Pichler W, Sanchez-Borges M, Shiohara T, Thong BY. International Consensus on drug allergy. Allergy. 2014 Apr; 69(4):420-37. PMID: 24697291.
    Citations: 55     Fields:    Translation:Humans
  105. Mezzano V, Giavina-Bianchi P, Picard M, Caiado J, Castells M. Drug desensitization in the management of hypersensitivity reactions to monoclonal antibodies and chemotherapy. BioDrugs. 2014 Apr; 28(2):133-44. PMID: 23990250.
    Citations: 3     Fields:    Translation:Humans
  106. Prieto-García A, Castells MC, Hansbro PM, Stevens RL. Mast cell-restricted tetramer-forming tryptases and their beneficial roles in hemostasis and blood coagulation. Immunol Allergy Clin North Am. 2014 May; 34(2):263-81. PMID: 24745673.
    Citations: 1     Fields:    Translation:HumansCells
  107. Dewachter P, Castells MC, Hepner DL, Mouton-Faivre C. Perioperative management of patients with mastocytosis. Anesthesiology. 2014 Mar; 120(3):753-9. PMID: 24135579.
    Citations: 2     Fields:    Translation:Humans
  108. Picard M, Matulonis UA, Castells M. Chemotherapy hypersensitivity reactions in ovarian cancer. J Natl Compr Canc Netw. 2014 Mar 01; 12(3):389-402. PMID: 24616544.
    Citations: 1     Fields:    Translation:Humans
  109. Logsdon S, Ramirez-Avila L, Castells M, Dioun A. Successful rifampin desensitization in a pediatric patient with latent tuberculosis. Pediatr Allergy Immunol. 2014 Jun; 25(4):404-5. PMID: 24417546.
    Citations: 2     Fields:    Translation:Humans
  110. Prieto-García A, Castells MC, Stevens RL. Mast cell-derived htryptase-beta functions as a potent anticoagulant by proteolytically damaging fibrinogen. J Investig Allergol Clin Immunol. 2014; 24(4):286-7. PMID: 25219118.
    Citations:    Fields:    Translation:Humans
  111. Galvão VR, Aun MV, Kalil J, Castells M, Giavina-Bianchi P. Clinical and laboratory improvement after intravenous immunoglobulin in drug reaction with eosinophilia and systemic symptoms. J Allergy Clin Immunol Pract. 2014 Jan-Feb; 2(1):107-10. PMID: 24565781.
    Citations: 4     Fields:    Translation:Humans
  112. Castells MC. Practical advances in drug hypersensitivity. J Allergy Clin Immunol Pract. 2014 Jan-Feb; 2(1):1-2. PMID: 24565762.
    Citations:    Fields:    Translation:Humans
  113. Lieberman P, Castells M. Desensitization to chemotherapeutic agents. J Allergy Clin Immunol Pract. 2014 Jan-Feb; 2(1):116-7. PMID: 24565784.
    Citations: 1     Fields:    Translation:Humans
  114. Jennings S, Russell N, Jennings B, Slee V, Sterling L, Castells M, Valent P, Akin C. The Mastocytosis Society survey on mast cell disorders: patient experiences and perceptions. J Allergy Clin Immunol Pract. 2014 Jan-Feb; 2(1):70-6. PMID: 24565772.
    Citations: 8     Fields:    Translation:Humans
  115. Hepner DL, Castells M, Mouton-Faivre C, Dewachter P. Anaphylaxis in the clinical setting of obstetric anesthesia: a literature review. Anesth Analg. 2013 Dec; 117(6):1357-67. PMID: 24257386.
    Citations: 2     Fields:    Translation:Humans
  116. Giavina-Bianchi P, Caiado J, Picard M, Pur Ozyigit L, Mezzano V, Castells M. Rapid desensitization to chemotherapy and monoclonal antibodies is effective and safe. Allergy. 2013 Nov; 68(11):1482-3. PMID: 24351069.
    Citations:    Fields:    Translation:Humans
  117. Castells M, Milhas D, Gandy C, Thibault B, Rafii A, Delord JP, Couderc B. Microenvironment mesenchymal cells protect ovarian cancer cell lines from apoptosis by inhibiting XIAP inactivation. Cell Death Dis. 2013 Oct 31; 4:e887. PMID: 24176845.
    Citations: 19     Fields:    Translation:HumansCells
  118. Caiado J, Venemalm L, Pereira-Santos MC, Costa L, Barbosa MP, Castells M. Carboplatin-, oxaliplatin-, and cisplatin-specific IgE: cross-reactivity and value in the diagnosis of carboplatin and oxaliplatin allergy. J Allergy Clin Immunol Pract. 2013 Sep-Oct; 1(5):494-500. PMID: 24565621.
    Citations: 9     Fields:    Translation:Humans
  119. Cernadas JR, Santos N, Pinto C, Mota PC, Castells M. Hypersensitivity reaction and tolerance induction to ethambutol. Case Rep Med. 2013; 2013:208797. PMID: 23983702.
    Citations: 1     
  120. Castells MC. In Person. J Allergy Clin Immunol. 2013 Jul; 132(1):24A-25A. PMID: 23971080.
    Citations:    Fields:    Translation:HumansCells
  121. Picard M, Giavina-Bianchi P, Mezzano V, Castells M. Expanding spectrum of mast cell activation disorders: monoclonal and idiopathic mast cell activation syndromes. Clin Ther. 2013 May; 35(5):548-62. PMID: 23642289.
    Citations: 15     Fields:    Translation:HumansCells
  122. Woessner KM, Castells M. NSAID single-drug-induced reactions. Immunol Allergy Clin North Am. 2013 May; 33(2):237-49. PMID: 23639711.
    Citations: 3     Fields:    Translation:Humans
  123. Cardet JC, Castells MC, Hamilton MJ. Immunology and clinical manifestations of non-clonal mast cell activation syndrome. Curr Allergy Asthma Rep. 2013 Feb; 13(1):10-8. PMID: 23212667.
    Citations: 6     Fields:    Translation:HumansAnimalsCells
  124. Ryan RJ, Akin C, Castells M, Wills M, Selig MK, Nielsen GP, Ferry JA, Hornick JL. Mast cell sarcoma: a rare and potentially under-recognized diagnostic entity with specific therapeutic implications. Mod Pathol. 2013 Apr; 26(4):533-43. PMID: 23196796.
    Citations: 8     Fields:    Translation:Humans
  125. Khan FS, Stewart DK, Brunzell JD, Natrajan KM, Castells MC, Henderson WR, Ayars AG. Successful desensitization to rosuvastatin in a patient with a history of anaphylaxis to multiple statins. J Allergy Clin Immunol. 2013 Jan; 131(1):234-6. PMID: 23177998.
    Citations:    Fields:    Translation:Humans
  126. Morgan RJ, Alvarez RD, Armstrong DK, Burger RA, Castells M, Chen LM, Copeland L, Crispens MA, Gershenson D, Gray H, Hakam A, Havrilesky LJ, Johnston C, Lele S, Martin L, Matulonis UA, O'Malley DM, Penson RT, Remmenga SW, Sabbatini P, Santoso JT, Schilder RJ, Schink J, Teng N, Werner TL, Hughes M, Dwyer MA. Ovarian cancer, version 3.2012. J Natl Compr Canc Netw. 2012 Nov 01; 10(11):1339-49. PMID: 23138163.
    Citations: 19     Fields:    Translation:Humans
  127. Bankova LG, Walter JE, Iyengar SR, Lorenzo ME, Hornick JL, Castells MC. Generalized bullous eruption after routine vaccination in a child with diffuse cutaneous mastocytosis. J Allergy Clin Immunol Pract. 2013 Jan; 1(1):94-6. PMID: 24229828.
    Citations: 4     Fields:    Translation:HumansPHPublic Health
  128. Bavbek S, Ataman S, Bankova L, Castells M. Injection site reaction to adalimumab: Positive skin test and successful rapid desensitisation. Allergol Immunopathol (Madr). 2013 May-Jun; 41(3):204-6. PMID: 23063342.
    Citations: 2     Fields:    Translation:Humans
  129. Castells M, Sancho-Serra Mdel C, Simarro M. Hypersensitivity to antineoplastic agents: mechanisms and treatment with rapid desensitization. Cancer Immunol Immunother. 2012 Sep; 61(9):1575-84. PMID: 22576054.
    Citations: 19     Fields:    Translation:Humans
  130. del Carmen Sancho M, Breslow R, Sloane D, Castells M. Desensitization for hypersensitivity reactions to medications. Chem Immunol Allergy. 2012; 97:217-33. PMID: 22613865.
    Citations: 6     Fields:    Translation:AnimalsCells
  131. Laidlaw TM, Kidder MS, Bhattacharyya N, Xing W, Shen S, Milne GL, Castells MC, Chhay H, Boyce JA. Cysteinyl leukotriene overproduction in aspirin-exacerbated respiratory disease is driven by platelet-adherent leukocytes. Blood. 2012 Apr 19; 119(16):3790-8. PMID: 22262771.
    Citations: 48     Fields:    Translation:HumansCells
  132. Prieto-García A, Zheng D, Adachi R, Xing W, Lane WS, Chung K, Anderson P, Hansbro PM, Castells M, Stevens RL. Mast cell restricted mouse and human tryptase·heparin complexes hinder thrombin-induced coagulation of plasma and the generation of fibrin by proteolytically destroying fibrinogen. J Biol Chem. 2012 Mar 09; 287(11):7834-44. PMID: 22235124.
    Citations: 17     Fields:    Translation:HumansAnimalsCells
  133. Hong DI, Bankova L, Cahill KN, Kyin T, Castells MC. Allergy to monoclonal antibodies: cutting-edge desensitization methods for cutting-edge therapies. Expert Rev Clin Immunol. 2012 Jan; 8(1):43-52; quiz 53-4. PMID: 22149339.
    Citations: 11     Fields:    Translation:Humans
  134. Thong BY, Mirakian R, Castells M, Pichler W, Romano A, Bonadonna P, Diana D, Kowalski M, Yanez A, Lleonart R, Sanchez-Borges M, Demoly P. A world allergy organization international survey on diagnostic procedures and therapies in drug allergy/hypersensitivity. World Allergy Organ J. 2011 Dec; 4(12):257-70. PMID: 23268453.
    Citations: 8     
  135. Levy JH, Castells MC. Perioperative anaphylaxis and the United States perspective. Anesth Analg. 2011 Nov; 113(5):979-81. PMID: 22021796.
    Citations: 2     Fields:    Translation:Humans
  136. Valent P, Akin C, Arock M, Brockow K, Butterfield JH, Carter MC, Castells M, Escribano L, Hartmann K, Lieberman P, Nedoszytko B, Orfao A, Schwartz LB, Sotlar K, Sperr WR, Triggiani M, Valenta R, Horny HP, Metcalfe DD. Definitions, criteria and global classification of mast cell disorders with special reference to mast cell activation syndromes: a consensus proposal. Int Arch Allergy Immunol. 2012; 157(3):215-25. PMID: 22041891.
    Citations: 64     Fields:    Translation:HumansCells
  137. Liu A, Fanning L, Chong H, Fernandez J, Sloane D, Sancho-Serra M, Castells M. Desensitization regimens for drug allergy: state of the art in the 21st century. Clin Exp Allergy. 2011 Dec; 41(12):1679-89. PMID: 21883538.
    Citations: 7     Fields:    Translation:Humans
  138. Castells M, Metcalfe DD, Escribano L. Diagnosis and treatment of cutaneous mastocytosis in children: practical recommendations. Am J Clin Dermatol. 2011 Aug 01; 12(4):259-70. PMID: 21668033.
    Citations: 16     Fields:    Translation:HumansAnimalsCells
  139. Dewachter P, Mouton-Faivre C, Castells MC, Hepner DL. Anesthesia in the patient with multiple drug allergies: are all allergies the same? Curr Opin Anaesthesiol. 2011 Jun; 24(3):320-5. PMID: 21494128.
    Citations: 10     Fields:    Translation:HumansAnimals
  140. Hamilton MJ, Hornick JL, Akin C, Castells MC, Greenberger NJ. Mast cell activation syndrome: a newly recognized disorder with systemic clinical manifestations. J Allergy Clin Immunol. 2011 Jul; 128(1):147-152.e2. PMID: 21621255.
    Citations: 23     Fields:    Translation:HumansCells
  141. Bavbek S, Aydin O, Ataman S, Cahill K, Castells M. Injection-site reaction to etanercept: role of skin test in the diagnosis of such reaction and successful desensitization. Allergy. 2011 Sep; 66(9):1256-7. PMID: 21507006.
    Citations: 1     Fields:    Translation:Humans
  142. Abonia JP, Castells M. Drug allergy in pediatric patients. Pediatr Ann. 2011 Apr; 40(4):200-4. PMID: 21485996.
    Citations: 1     Fields:    Translation:Humans
  143. Murali MR, Castells MC, Song JY, Dudzinski DM, Hasserjian RP. Case records of the Massachusetts General Hospital. Case 9-2011. A 37-year-old man with flushing and hypotension. N Engl J Med. 2011 Mar 24; 364(12):1155-65. PMID: 21428772.
    Citations: 4     Fields:    Translation:Humans
  144. Rachid R, Castells M, Cunningham-Rundles C, Bonilla FA. Association of anti-IgA antibodies with adverse reactions to ?-globulin infusion. J Allergy Clin Immunol. 2011 Jul; 128(1):228-230.e1. PMID: 21397310.
    Citations: 6     Fields:    Translation:Humans
  145. Sancho-Serra Mdel C, Simarro M, Castells M. Rapid IgE desensitization is antigen specific and impairs early and late mast cell responses targeting FceRI internalization. Eur J Immunol. 2011 Apr; 41(4):1004-13. PMID: 21360700.
    Citations: 20     Fields:    Translation:AnimalsCells
  146. Romano A, Torres MJ, Castells M, Sanz ML, Blanca M. Diagnosis and management of drug hypersensitivity reactions. J Allergy Clin Immunol. 2011 Mar; 127(3 Suppl):S67-73. PMID: 21354502.
    Citations: 28     Fields:    Translation:HumansCells
  147. Prieto-Garcia A, Sloane DE, Gargiulo AR, Feldweg AM, Castells M. Autoimmune progesterone dermatitis: clinical presentation and management with progesterone desensitization for successful in vitro fertilization. Fertil Steril. 2011 Mar 01; 95(3):1121.e9-13. PMID: 21092951.
    Citations: 5     Fields:    Translation:Humans
  148. Cernadas JR, Brockow K, Romano A, Aberer W, Torres MJ, Bircher A, Campi P, Sanz ML, Castells M, Demoly P, Pichler WJ. General considerations on rapid desensitization for drug hypersensitivity - a consensus statement. Allergy. 2010 Nov; 65(11):1357-66. PMID: 20716314.
    Citations: 28     Fields:    Translation:Humans
  149. Ross JJ, Saavedra A, Vleugels RA, Liu A, Castells MC. Interactive medical case. A rash hypothesis. N Engl J Med. 2010 Jun 17; 362(24):e69. PMID: 20560180.
    Citations: 1     Fields:    Translation:Humans
  150. Farber MK, Angelo TE, Castells M, Tsen LC. Anesthetic management of a patient with an allergy to propylene glycol and parabens. Anesth Analg. 2010 Mar 01; 110(3):839-42. PMID: 20185660.
    Citations: 2     Fields:    Translation:Humans
  151. Limsuwan T, Castells MC. Outcomes and safety of rapid desensitization for chemotherapy hypersensitivity. Expert Opin Drug Saf. 2010 Jan; 9(1):39-53. PMID: 20001753.
    Citations: 3     Fields:    Translation:Humans
  152. Brennan PJ, Rodriguez Bouza T, Hsu FI, Sloane DE, Castells MC. Hypersensitivity reactions to mAbs: 105 desensitizations in 23 patients, from evaluation to treatment. J Allergy Clin Immunol. 2009 Dec; 124(6):1259-66. PMID: 19910036.
    Citations: 26     Fields:    Translation:Humans
  153. Legere HJ, Palis RI, Rodriguez Bouza T, Uluer AZ, Castells MC. A safe protocol for rapid desensitization in patients with cystic fibrosis and antibiotic hypersensitivity. J Cyst Fibros. 2009 Dec; 8(6):418-24. PMID: 19740711.
    Citations: 4     Fields:    Translation:Humans
  154. Castells M. Rapid desensitization for hypersensitivity reactions to medications. Immunol Allergy Clin North Am. 2009 Aug; 29(3):585-606. PMID: 19563999.
    Citations: 17     Fields:    Translation:Humans
  155. Breslow RG, Caiado J, Castells MC. Acetylsalicylic acid and montelukast block mast cell mediator-related symptoms during rapid desensitization. Ann Allergy Asthma Immunol. 2009 Feb; 102(2):155-60. PMID: 19230468.
    Citations: 7     Fields:    Translation:HumansCellsCTClinical Trials
  156. Castells MC, Tennant NM, Sloane DE, Hsu FI, Barrett NA, Hong DI, Laidlaw TM, Legere HJ, Nallamshetty SN, Palis RI, Rao JJ, Berlin ST, Campos SM, Matulonis UA. Hypersensitivity reactions to chemotherapy: outcomes and safety of rapid desensitization in 413 cases. J Allergy Clin Immunol. 2008 Sep; 122(3):574-80. PMID: 18502492.
    Citations: 43     Fields:    Translation:Humans
  157. Castells MC, Tennant NM, Sloane DE, Hsu FI, Berlin ST, Campos SM, Matulonis UA. Anaphylactic and anaphylactoid reactions to chemotherapy: outcomes and safety of rapid intravenous and intraperitoneal desensitizations in 413 cases. J Clin Oncol. 2008 May 20; 26(15_suppl):5526. PMID: 27950844.
    Citations:    
  158. González de Olano D, Alvarez-Twose I, Esteban-López MI, Sánchez-Muñoz L, de Durana MD, Vega A, García-Montero A, González-Mancebo E, Belver T, Herrero-Gil MD, Fernández-Rivas M, Orfao A, de la Hoz B, Castells MC, Escribano L. Safety and effectiveness of immunotherapy in patients with indolent systemic mastocytosis presenting with Hymenoptera venom anaphylaxis. J Allergy Clin Immunol. 2008 Feb; 121(2):519-26. PMID: 18177694.
    Citations: 20     Fields:    Translation:HumansAnimals
  159. Castells MC. Hypersensitivity to antineoplastic agents. Curr Pharm Des. 2008; 14(27):2892-901. PMID: 18991707.
    Citations: 4     Fields:    Translation:HumansAnimals
  160. Lopez X, Castells M, Ricker A, Velazquez EF, Mun E, Goldfine AB. Human insulin analog--induced lipoatrophy. Diabetes Care. 2008 Mar; 31(3):442-4. PMID: 18162498.
    Citations: 9     Fields:    Translation:HumansCells
  161. González de Olano D, de la Hoz Caballer B, Núñez López R, Sánchez Muñoz L, Cuevas Agustín M, Diéguez MC, Alvarez Twose I, Castells MC, Escribano Mora L. Prevalence of allergy and anaphylactic symptoms in 210 adult and pediatric patients with mastocytosis in Spain: a study of the Spanish network on mastocytosis (REMA). Clin Exp Allergy. 2007 Oct; 37(10):1547-55. PMID: 17883734.
    Citations: 25     Fields:    Translation:Humans
  162. Culp JA, Palis RI, Castells MC, Lucas SR, Borish L. Perioperative anaphylaxis in a 44-year-old man. Allergy Asthma Proc. 2007 Sep-Oct; 28(5):602-5. PMID: 18034982.
    Citations: 1     Fields:    Translation:Humans
  163. Valent P, Akin C, Escribano L, Födinger M, Hartmann K, Brockow K, Castells M, Sperr WR, Kluin-Nelemans HC, Hamdy NA, Lortholary O, Robyn J, van Doormaal J, Sotlar K, Hauswirth AW, Arock M, Hermine O, Hellmann A, Triggiani M, Niedoszytko M, Schwartz LB, Orfao A, Horny HP, Metcalfe DD. Standards and standardization in mastocytosis: consensus statements on diagnostics, treatment recommendations and response criteria. Eur J Clin Invest. 2007 Jun; 37(6):435-53. PMID: 17537151.
    Citations: 115     Fields:    Translation:Humans
  164. Macy E, Bernstein JA, Castells MC, Gawchik SM, Lee TH, Settipane RA, Simon RA, Wald J, Woessner KM. Aspirin challenge and desensitization for aspirin-exacerbated respiratory disease: a practice paper. Ann Allergy Asthma Immunol. 2007 Feb; 98(2):172-4. PMID: 17304886.
    Citations: 23     Fields:    Translation:Humans
  165. Castells M. Desensitization for drug allergy. Curr Opin Allergy Clin Immunol. 2006 Dec; 6(6):476-81. PMID: 17088655.
    Citations: 12     Fields:    Translation:HumansCells
  166. Castells M. Mast cell mediators in allergic inflammation and mastocytosis. Immunol Allergy Clin North Am. 2006 Aug; 26(3):465-85. PMID: 16931289.
    Citations: 19     Fields:    Translation:HumansCells
  167. Castells M. Rapid desensitization for hypersensitivity reactions to chemotherapy agents. Curr Opin Allergy Clin Immunol. 2006 Aug; 6(4):271-7. PMID: 16825867.
    Citations: 5     Fields:    Translation:Humans
  168. Castells M. Rapid desensitization of hypersensitivity reactions to chemotherapy agents. Curr Drug Saf. 2006 Aug; 1(3):243-51. PMID: 18690934.
    Citations: 4     Fields:    Translation:Humans
  169. Castells MC. Extracutaneous mastocytoma. J Allergy Clin Immunol. 2006 Jun; 117(6):1513-5. PMID: 16751029.
    Citations: 1     Fields:    Translation:HumansCells
  170. Santos DD, Hatjiharissi E, Tournilhac O, Chemaly MZ, Leleu X, Xu L, Patterson C, Branagan AR, Manning RJ, Ho AW, Hunter ZR, Dimmock EA, Kutok JL, Churchill WH, Castells MC, Tai YT, Anderson KC, Treon SP. CD52 is expressed on human mast cells and is a potential therapeutic target in Waldenstrom's Macroglobulinemia and mast cell disorders. Clin Lymphoma Myeloma. 2006 May; 6(6):478-83. PMID: 16796779.
    Citations: 9     Fields:    Translation:HumansCells
  171. Escribano L, Akin C, Castells M, Schwartz LB. Current options in the treatment of mast cell mediator-related symptoms in mastocytosis. Inflamm Allergy Drug Targets. 2006 Jan; 5(1):61-77. PMID: 16613565.
    Citations: 20     Fields:    Translation:HumansAnimalsCells
  172. Lee CW, Mitchell RN, Horan RF, Castells MC. Cardiogenic shock and peripheral eosinophilia in a young woman. Ann Allergy Asthma Immunol. 2005 Sep; 95(3):229-33. PMID: 16200812.
    Citations: 2     Fields:    Translation:Humans
  173. Lee CW, Matulonis UA, Castells MC. Rapid inpatient/outpatient desensitization for chemotherapy hypersensitivity: standard protocol effective in 57 patients for 255 courses. Gynecol Oncol. 2005 Nov; 99(2):393-9. PMID: 16054201.
    Citations: 13     Fields:    Translation:HumansCTClinical Trials
  174. Lee CW, Matulonis UA, Campos SM, Gross AH, Hayes CM, Keenan KT, Castells MC. Rapid inpatient and outpatient desensitization for carboplatin or paclitaxel hypersensitivity: A protocol effective in patients with gynecologic malignancies. J Clin Oncol. 2005 Jun; 23(16_suppl):5090. PMID: 27947082.
    Citations:    
  175. Morales AR, Shah N, Castells M. Antigen-IgE desensitization in signal transducer and activator of transcription 6-deficient mast cells by suboptimal doses of antigen. Ann Allergy Asthma Immunol. 2005 May; 94(5):575-80. PMID: 15945561.
    Citations: 7     Fields:    Translation:AnimalsCellsPHPublic Health
  176. Feldweg AM, Lee CW, Matulonis UA, Castells M. Rapid desensitization for hypersensitivity reactions to paclitaxel and docetaxel: a new standard protocol used in 77 successful treatments. Gynecol Oncol. 2005 Mar; 96(3):824-9. PMID: 15721432.
    Citations: 13     Fields:    Translation:Humans
  177. Lee CW, Matulonis UA, Castells MC. Carboplatin hypersensitivity: a 6-h 12-step protocol effective in 35 desensitizations in patients with gynecological malignancies and mast cell/IgE-mediated reactions. Gynecol Oncol. 2004 Nov; 95(2):370-6. PMID: 15491759.
    Citations: 12     Fields:    Translation:HumansCellsCTClinical Trials
  178. Castells MC. Mastocytosis: classification, diagnosis, and clinical presentation. Allergy Asthma Proc. 2004 Jan-Feb; 25(1):33-6. PMID: 15055560.
    Citations: 6     Fields:    
  179. Lee CW, Castells MC. Perioperative anaphylaxis to cefazolin. Allergy Asthma Proc. 2004 Jan-Feb; 25(1):23-6. PMID: 15055557.
    Citations: 1     Fields:    Translation:Humans
  180. Hepner DL, Castells MC, Tsen LC. Should local anesthetic allergy testing be routinely performed during pregnancy? Anesth Analg. 2003 Dec; 97(6):1853-4; author reply 1854. PMID: 14633575.
    Citations:    Fields:    Translation:Humans
  181. Hepner DL, Castells MC. Anaphylaxis during the perioperative period. Anesth Analg. 2003 Nov; 97(5):1381-95. PMID: 14570656.
    Citations: 42     Fields:    Translation:Humans
  182. Hepner DL, Castells MC. Latex allergy: an update. Anesth Analg. 2003 Apr; 96(4):1219-29. PMID: 12651689.
    Citations: 6     Fields:    Translation:Humans
  183. Castells MC, Horan RF, Sheffer AL. Exercise-induced Anaphylaxis. Curr Allergy Asthma Rep. 2003 Jan; 3(1):15-21. PMID: 12542988.
    Citations: 9     Fields:    Translation:Humans
  184. Escribano L, Akin C, Castells M, Orfao A, Metcalfe DD. Mastocytosis: current concepts in diagnosis and treatment. Ann Hematol. 2002 Dec; 81(12):677-90. PMID: 12483363.
    Citations: 36     Fields:    Translation:HumansCells
  185. Price KS, Castells MC. Taxol reactions. Allergy Asthma Proc. 2002 May-Jun; 23(3):205-8. PMID: 12125509.
    Citations: 7     Fields:    Translation:Humans
  186. Castells M, Austen KF. Mastocytosis: mediator-related signs and symptoms. Int Arch Allergy Immunol. 2002 Feb; 127(2):147-52. PMID: 11919427.
    Citations: 17     Fields:    Translation:HumansCells
  187. Abonia JP, Castells MC. Common variable immunodeficiency. Allergy Asthma Proc. 2002 Jan-Feb; 23(1):53-7. PMID: 11894736.
    Citations: 2     Fields:    Translation:Humans
  188. Castells MC, Klickstein LB, Hassani K, Cumplido JA, Lacouture ME, Austen KF, Katz HR. gp49B1-alpha(v)beta3 interaction inhibits antigen-induced mast cell activation. Nat Immunol. 2001 May; 2(5):436-42. PMID: 11323698.
    Citations: 16     Fields:    Translation:AnimalsCells
  189. Mutinga M, Castells M, Horan R, Farraye FA. Successful desensitization to 6-mercaptopurine in a patient with Crohn's disease. Am J Gastroenterol. 2000 May; 95(5):1383-4. PMID: 10811376.
    Citations: 1     Fields:    Translation:Humans
  190. McCormick MJ, Castells MC, Austen KF, Katz HR. The gp49A gene has extensive sequence conservation with the gp49B gene and provides gp49A protein, a unique member of a large family of activating and inhibitory receptors of the immunoglobulin superfamily. Immunogenetics. 1999 Dec; 50(5-6):286-94. PMID: 10630292.
    Citations: 4     Fields:    Translation:HumansAnimalsCells
  191. Castells MC, Horan RF, Sheffer AL. Exercise-induced anaphylaxis (EIA). Clin Rev Allergy Immunol. 1999; 17(4):413-24. PMID: 10829811.
    Citations: 6     Fields:    Translation:Humans
  192. Castells M, Boyce J. Transfer of peanut allergy by a liver allograft. N Engl J Med. 1998 Jan 15; 338(3):202-3. PMID: 9441233.
    Citations: 3     Fields:    Translation:HumansAnimals
  193. Castells M. Update on mast cells and mast cell precursors and hypersensitivity responses. Allergy Asthma Proc. 1997 Sep-Oct; 18(5):287-92. PMID: 9337422.
    Citations: 1     Fields:    Translation:HumansAnimalsCells
  194. Katz HR, Vivier E, Castells MC, McCormick MJ, Chambers JM, Austen KF. Mouse mast cell gp49B1 contains two immunoreceptor tyrosine-based inhibition motifs and suppresses mast cell activation when coligated with the high-affinity Fc receptor for IgE. Proc Natl Acad Sci U S A. 1996 Oct 01; 93(20):10809-14. PMID: 8855262.
    Citations: 20     Fields:    Translation:AnimalsCells
  195. Castells MC, Friend DS, Bunnell CA, Hu X, Kraus M, Osteen RT, Austen KF. The presence of membrane-bound stem cell factor on highly immature nonmetachromatic mast cells in the peripheral blood of a patient with aggressive systemic mastocytosis. J Allergy Clin Immunol. 1996 Oct; 98(4):831-40. PMID: 8876560.
    Citations: 10     Fields:    Translation:HumansCells
  196. Castells MC. Surface makers for mast cell subtypes: low affinity IgG receptors and gp49 family. Allerg Immunol (Paris). 1994 Apr; 26(4):127-31. PMID: 8031457.
    Citations: 2     Fields:    Translation:HumansAnimalsCells
  197. Castells MC, Wu X, Arm JP, Austen KF, Katz HR. Cloning of the gp49B gene of the immunoglobulin superfamily and demonstration that one of its two products is an early-expressed mast cell surface protein originally described as gp49. J Biol Chem. 1994 Mar 18; 269(11):8393-401. PMID: 8132564.
    Citations: 12     Fields:    Translation:HumansAnimalsCells
  198. Kaye RE, Fruman DA, Bierer BE, Albers MW, Zydowsky LD, Ho SI, Jin YJ, Castells MC, Schreiber SL, Walsh CT, et al. Effects of cyclosporin A and FK506 on Fc epsilon receptor type I-initiated increases in cytokine mRNA in mouse bone marrow-derived progenitor mast cells: resistance to FK506 is associated with a deficiency in FK506-binding protein FKBP12. Proc Natl Acad Sci U S A. 1992 Sep 15; 89(18):8542-6. PMID: 1382293.
    Citations: 17     Fields:    Translation:AnimalsCells
  199. Castells M, Schwartz LB. Tryptase levels in nasal-lavage fluid as an indicator of the immediate allergic response. J Allergy Clin Immunol. 1988 Sep; 82(3 Pt 1):348-55. PMID: 3049743.
    Citations: 20     Fields:    Translation:HumansCells
  200. Schwartz LB, Irani AM, Roller K, Castells MC, Schechter NM. Quantitation of histamine, tryptase, and chymase in dispersed human T and TC mast cells. J Immunol. 1987 Apr 15; 138(8):2611-5. PMID: 3549903.
    Citations: 79     Fields:    Translation:HumansCells
  201. Castells MC, Irani AM, Schwartz LB. Evaluation of human peripheral blood leukocytes for mast cell tryptase. J Immunol. 1987 Apr 01; 138(7):2184-9. PMID: 3549898.
    Citations: 32     Fields:    Translation:HumansCells
  202. Castells MC, Pascual C, Esteban MM, Ojeda JA. Allergy to white potato. J Allergy Clin Immunol. 1986 Dec; 78(6):1110-4. PMID: 3782675.
    Citations: 5     Fields:    Translation:HumansAnimals
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.