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Madhusmita Misra, M.B.,B.S.

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Overview

Mentoring
Available: 11/01/19, Expires: 11/30/23

Adolescence and young adulthood are often a time for the onset of eating disorders, as well as a key window of neurocognitive development and hormone changes. Estrogen dysregulation is common in eating disorders and is associated with impaired cognitive flexibility and altered reward responsiveness and valuation, which in turn, may play a mechanistic role in the onset and course of eating disorders. This proposal utilizes physiologic estrogen as a probe, studying its role in cognitive flexibility, reward responsiveness and valuation, and in turn, eating disorder psychopathology, in eating disorders. The student will work on scoring study instruments, the study database, and recruitment of study participants.


Research
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. R01DK124223 (LAWSON, ELIZABETH AUSTEN) Sep 17, 2020 - Jun 30, 2025
    NIH
    Oxytocin as a Neuroendocrine Therapy for Obesity in Youth
    Role: Co-Principal Investigator
  2. R01DK122581 (MITCHELL, DEBORAH MICHELLE) Sep 12, 2019 - Aug 31, 2024
    NIH
    Determinants of bone microarchitectural compromise in youth with type 1 diabetes
    Role: Co-Principal Investigator
  3. R01MH116205 (MISRA, MADHUSMITA) Mar 8, 2019 - Dec 31, 2023
    NIH
    The Role of Estrogen in the Neurobiology of Eating Disorders: A Study of Cognitive Flexibility and Reward in Eating Disorders
    Role: Principal Investigator
  4. R01DK103946 (MISRA, MADHUSMITA) Aug 6, 2015 - Jul 31, 2021
    NIH
    Bone Metabolism in Adolescents Undergoing Bariatric Surgery
    Role: Co-Principal Investigator
  5. R01MH103402 (MISRA, MADHUSMITA) Apr 1, 2014 - Mar 31, 2020
    NIH
    Homeostatic and Hedonic Food Motivation Underlying Eating Disorder Trajectories
    Role: Co-Principal Investigator

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Maya J, Misra M. The female athlete triad: review of current literature. Curr Opin Endocrinol Diabetes Obes. 2022 02 01; 29(1):44-51. PMID: 34812202.
    Citations:    Fields:    Translation:Humans
  2. De Souza MJ, Strock NCA, Ricker EA, Koltun KJ, Barrack M, Joy E, Nattiv A, Hutchinson M, Misra M, Williams NI. The Path Towards Progress: A Critical Review to Advance the Science of the Female and Male Athlete Triad and Relative Energy Deficiency in Sport. Sports Med. 2022 Jan; 52(1):13-23. PMID: 34665451.
    Citations: 1     Fields:    
  3. J Silla KE, S Brigham K, Goldstein M, Misra M, Singhal V. Clinical, biochemical, and hematological characteristics of community-dwelling adolescent and young adult males with anorexia nervosa. Int J Eat Disord. 2021 12; 54(12):2213-2217. PMID: 34617624.
    Citations:    Fields:    
  4. Dreier MJ, Van De Water AL, Kahn DL, Becker KR, Eddy KT, Thomas JJ, Holsen LM, Lawson EA, Misra M, Lyall AE, Breithaupt L. Meta-analysis of structural MRI studies in anorexia nervosa and the role of recovery: a systematic review protocol. Syst Rev. 2021 09 13; 10(1):247. PMID: 34517926.
    Citations:    Fields:    Translation:Humans
  5. Harshman SG, Jo J, Kuhnle M, Hauser K, Murray HB, Becker KR, Misra M, Eddy KT, Micali N, Lawson EA, Thomas JJ. A Moving Target: How We Define Avoidant/Restrictive Food Intake Disorder Can Double Its Prevalence. J Clin Psychiatry. 2021 09 07; 82(5). PMID: 34496463.
    Citations:    Fields:    Translation:Humans
  6. Haines MS, Kimball A, Meenaghan E, Bachmann KN, Santoso K, Eddy KT, Singhal V, Ebrahimi S, Dechant E, Weigel T, Ciotti L, Keane RJ, Gleysteen S, Mickley D, Bredella MA, Tan CO, Gupta R, Misra M, Schoenfeld D, Klibanski A, Miller KK. Sequential Therapy With Recombinant Human IGF-1 Followed by Risedronate Increases Spine Bone Mineral Density in Women With Anorexia Nervosa: A Randomized, Placebo-Controlled Trial. J Bone Miner Res. 2021 11; 36(11):2116-2126. PMID: 34355814.
    Citations:    Fields:    Translation:Humans
  7. Ironside M, Moser AD, Holsen LM, Zuo CS, Du F, Perlo S, Richards CE, Duda JM, Chen X, Nickerson LD, Null KE, Nascimento N, Crowley DJ, Misra M, Goldstein JM, Pizzagalli DA. Reductions in rostral anterior cingulate GABA are associated with stress circuitry in females with major depression: a multimodal imaging investigation. Neuropsychopharmacology. 2021 11; 46(12):2188-2196. PMID: 34363015.
    Citations:    Fields:    Translation:Humans
  8. Crane JL, Misra M. Editorial: Management of Bone Disorders in Children. Front Endocrinol (Lausanne). 2021; 12:725655. PMID: 34290674.
    Citations:    Fields:    Translation:Humans
  9. Nattiv A, De Souza MJ, Koltun KJ, Misra M, Kussman A, Williams NI, Barrack MT, Kraus E, Joy E, Fredericson M. The Male Athlete Triad-A Consensus Statement From the Female and Male Athlete Triad Coalition Part 1: Definition and Scientific Basis. Clin J Sport Med. 2021 Jul 01; 31(4):335-348. PMID: 34091537.
    Citations: 4     Fields:    Translation:Humans
  10. Fredericson M, Kussman A, Misra M, Barrack MT, De Souza MJ, Kraus E, Koltun KJ, Williams NI, Joy E, Nattiv A. The Male Athlete Triad-A Consensus Statement From the Female and Male Athlete Triad Coalition Part II: Diagnosis, Treatment, and Return-To-Play. Clin J Sport Med. 2021 Jul 01; 31(4):349-366. PMID: 34091538.
    Citations: 1     Fields:    Translation:Humans
  11. Singhal V, Bose A, Slattery M, Haines MS, Goldstein MA, Gupta N, Brigham KS, Ebrahimi S, Javaras KN, Bouxsein ML, Eddy KT, Miller KK, Schoenfeld D, Klibanski A, Misra M. Effect of Transdermal Estradiol and Insulin-like Growth Factor-1 on Bone Endpoints of Young Women With Anorexia Nervosa. J Clin Endocrinol Metab. 2021 06 16; 106(7):2021-2035. PMID: 33693703.
    Citations: 2     Fields:    Translation:Humans
  12. Becker KR, Mancuso C, Dreier MJ, Asanza E, Breithaupt L, Slattery M, Plessow F, Micali N, Thomas JJ, Eddy KT, Misra M, Lawson EA. Ghrelin and PYY in low-weight females with avoidant/restrictive food intake disorder compared to anorexia nervosa and healthy controls. Psychoneuroendocrinology. 2021 07; 129:105243. PMID: 34049199.
    Citations: 1     Fields:    Translation:Humans
  13. Bredella MA, Karzar NH, Singhal V, Bose A, Animashaun A, Mitchell DM, Yu EW, Misra M. Impact of sleeve gastrectomy on bone outcomes in adolescents vs. adults with obesity. Bone. 2021 08; 149:115975. PMID: 33901724.
    Citations: 2     Fields:    Translation:Humans
  14. Baskaran C, Animashaun A, Rickard F, Toth AT, Eddy KT, Plessow F, Bredella MA, Misra M. Memory and Executive Function in Adolescent and Young Adult Females with Moderate to Severe Obesity Before and After Weight Loss Surgery. Obes Surg. 2021 07; 31(7):3372-3378. PMID: 33826084.
    Citations: 1     Fields:    Translation:Humans
  15. Kerem L, Van De Water AL, Kuhnle MC, Harshman S, Hauser K, Eddy KT, Becker KR, Misra M, Micali N, Thomas JJ, Holsen L, Lawson EA. Neurobiology of Avoidant/Restrictive Food Intake Disorder in Youth with Overweight/Obesity Versus Healthy Weight. J Clin Child Adolesc Psychol. 2021 Mar 26; 1-14. PMID: 33769133.
    Citations:    Fields:    
  16. Thomas JJ, Becker KR, Breithaupt L, Murray HB, Jo JH, Kuhnle MC, Dreier MJ, Harshman S, Kahn DL, Hauser K, Slattery M, Misra M, Lawson EA, Eddy KT. Cognitive-behavioral therapy for adults with avoidant/restrictive food intake disorder. J Behav Cogn Ther. 2021 Mar; 31(1):47-55. PMID: 34423319.
    Citations:    
  17. Misra M, Bredella MA. Bone Metabolism in Adolescents Undergoing Bariatric Surgery. J Clin Endocrinol Metab. 2021 01 23; 106(2):326-336. PMID: 33196832.
    Citations:    Fields:    Translation:Humans
  18. Castellanos LE, Misra M, Smith TR, Laws ER, Iorgulescu JB. The epidemiology and management patterns of pediatric pituitary tumors in the United States. Pituitary. 2021 Jun; 24(3):412-419. PMID: 33433891.
    Citations: 2     Fields:    Translation:Humans
  19. Singhal V, Karzar NH, Bose A, Buckless C, Ackerman KE, Bredella MA, Klibanski A, Misra M. Changes in marrow adipose tissue in relation to changes in bone parameters following estradiol replacement in adolescent and young adult females with functional hypothalamic amenorrhea. Bone. 2021 04; 145:115841. PMID: 33418100.
    Citations:    Fields:    Translation:Humans
  20. Joseph TV, Caksa S, Misra M, Mitchell DM. Hip Structural Analysis Reveals Impaired Hip Geometry in Girls With Type 1 Diabetes. J Clin Endocrinol Metab. 2020 12 01; 105(12). PMID: 32929477.
    Citations: 4     Fields:    Translation:Humans
  21. Duda JM, Moser AD, Zuo CS, Du F, Chen X, Perlo S, Richards CE, Nascimento N, Ironside M, Crowley DJ, Holsen LM, Misra M, Hudson JI, Goldstein JM, Pizzagalli DA. Repeatability and reliability of GABA measurements with magnetic resonance spectroscopy in healthy young adults. Magn Reson Med. 2021 05; 85(5):2359-2369. PMID: 33216412.
    Citations: 3     Fields:    Translation:Humans
  22. Bredella MA, Singhal V, Hazhir Karzar N, Animashaun A, Bose A, Stanford FC, Carmine B, Misra M. Effects of Sleeve Gastrectomy on Bone Marrow Adipose Tissue in Adolescents and Young Adults with Obesity. J Clin Endocrinol Metab. 2020 11 01; 105(11). PMID: 32827034.
    Citations: 3     Fields:    Translation:Humans
  23. Allen DB, Aye T, Boney CM, Eugster EA, Misra M, Singer K, Stafford D, Witchel SF, Zeitler P. Sustaining the Pediatric Endocrinology Workforce: Recommendations from the Pediatric Endocrine Society Workforce Task Force. J Pediatr. 2021 06; 233:4-7. PMID: 33137317.
    Citations: 1     Fields:    Translation:Humans
  24. Bredella MA, Singhal V, Hazhir Karzar N, Animashaun A, Bose A, Stanford FC, Carmine B, Misra M. Racial differences in lumbar marrow adipose tissue and volumetric bone mineral density in adolescents and young adults with obesity. Bone Rep. 2020 Dec; 13:100726. PMID: 33392365.
    Citations: 1     
  25. Pan CS, Weiss JJ, Fourman LT, Buckless C, Branch KL, Lee H, Torriani M, Misra M, Stanley TL. Effect of recombinant human growth hormone on liver fat content in young adults with nonalcoholic fatty liver disease. Clin Endocrinol (Oxf). 2021 02; 94(2):183-192. PMID: 33037656.
    Citations: 2     Fields:    Translation:Humans
  26. Thomas JJ, Becker KR, Kuhnle MC, Jo JH, Harshman SG, Wons OB, Keshishian AC, Hauser K, Breithaupt L, Liebman RE, Misra M, Wilhelm S, Lawson EA, Eddy KT. Cognitive-behavioral therapy for avoidant/restrictive food intake disorder: Feasibility, acceptability, and proof-of-concept for children and adolescents. Int J Eat Disord. 2020 10; 53(10):1636-1646. PMID: 32776570.
    Citations: 7     Fields:    Translation:Humans
  27. Singhal V, Youssef S, Misra M. Use of sleeve gastrectomy in adolescents and young adults with severe obesity. Curr Opin Pediatr. 2020 08; 32(4):547-553. PMID: 32692052.
    Citations:    Fields:    Translation:Humans
  28. Misra M, Animashaun A, Bose A, Singhal V, Stanford FC, Carmine B, Bredella MA. Impact of sleeve gastrectomy on hip structural analysis in adolescents and young adults with obesity. Surg Obes Relat Dis. 2020 Dec; 16(12):2022-2030. PMID: 32861645.
    Citations: 2     Fields:    Translation:Humans
  29. Nijjar JK, Weiss JJ, Misra M, Stanley TL. Utility and duration of leuprolide stimulation testing in children. J Pediatr Endocrinol Metab. 2020 Jul 20. PMID: 32692703.
    Citations:    Fields:    
  30. Campoverde Reyes KJ, Stanford FC, Singhal V, Animashaun AO, Bose A, Gleeson EL, Bredella MA, Misra M. Bone density, microarchitecture and strength estimates in white versus African American youth with obesity. Bone. 2020 09; 138:115514. PMID: 32622072.
    Citations: 1     Fields:    Translation:Humans
  31. Baskaran C, Bose A, Plessow F, Torre Flores L, Toth AT, Eddy KT, Bredella MA, Misra M. Depressive and anxiety symptoms and suicidality in adolescent and young adult females with moderate to severe obesity before and after weight loss surgery. Clin Obes. 2020 Oct; 10(5):e12381. PMID: 32558297.
    Citations: 1     Fields:    Translation:Humans
  32. Allaway HCM, Misra M, Southmayd EA, Stone MS, Weaver CM, Petkus DL, De Souza MJ. Are the Effects of Oral and Vaginal Contraceptives on Bone Formation in Young Women Mediated via the Growth Hormone-IGF-I Axis? Front Endocrinol (Lausanne). 2020; 11:334. PMID: 32612574.
    Citations: 1     Fields:    Translation:Humans
  33. Breithaupt L, Chunga-Iturry N, Lyall AE, Cetin-Karayumak S, Becker KR, Thomas JJ, Slattery M, Makris N, Plessow F, Pasternak O, Holsen LM, Kubicki M, Misra M, Lawson EA, Eddy KT. Developmental stage-dependent relationships between ghrelin levels and hippocampal white matter connections in low-weight anorexia nervosa and atypical anorexia nervosa. Psychoneuroendocrinology. 2020 09; 119:104722. PMID: 32512249.
    Citations: 3     Fields:    Translation:Humans
  34. Mitchell DM, Caksa S, Joseph T, Bouxsein ML, Misra M. Elevated HbA1c Is Associated with Altered Cortical and Trabecular Microarchitecture in Girls with Type 1 Diabetes. J Clin Endocrinol Metab. 2020 04 01; 105(4). PMID: 31761940.
    Citations: 9     Fields:    Translation:Humans
  35. Stanford FC, Mushannen T, Cortez P, Campoverde Reyes KJ, Lee H, Gee DW, Pratt JS, Boepple PA, Bredella MA, Misra M, Singhal V. Comparison of Short and Long-Term Outcomes of Metabolic and Bariatric Surgery in Adolescents and Adults. Front Endocrinol (Lausanne). 2020; 11:157. PMID: 32265846.
    Citations: 5     Fields:    Translation:Humans
  36. Bahamonde M, Misra M. Potential applications for rhIGF-I: Bone disease and IGFI. Growth Horm IGF Res. 2020 06; 52:101317. PMID: 32252004.
    Citations: 3     Fields:    Translation:HumansAnimals
  37. Aulinas A, Marengi DA, Galbiati F, Asanza E, Slattery M, Mancuso CJ, Wons O, Micali N, Bern E, Eddy KT, Thomas JJ, Misra M, Lawson EA. Medical comorbidities and endocrine dysfunction in low-weight females with avoidant/restrictive food intake disorder compared to anorexia nervosa and healthy controls. Int J Eat Disord. 2020 04; 53(4):631-636. PMID: 32198943.
    Citations: 6     Fields:    Translation:Humans
  38. Misra M, Singhal V, Carmine B, Bose A, Kelsey MM, Stanford FC, Bram J, Aidlen J, Inge T, Bouxsein ML, Bredella MA. Bone outcomes following sleeve gastrectomy in adolescents and young adults with obesity versus non-surgical controls. Bone. 2020 05; 134:115290. PMID: 32084562.
    Citations: 8     Fields:    Translation:HumansCTClinical Trials
  39. Wang SB, Mancuso CJ, Jo J, Keshishian AC, Becker KR, Plessow F, Izquierdo AM, Slattery M, Franko DL, Misra M, Lawson EA, Thomas JJ, Eddy KT. Restrictive eating, but not binge eating or purging, predicts suicidal ideation in adolescents and young adults with low-weight eating disorders. Int J Eat Disord. 2020 03; 53(3):472-477. PMID: 31886575.
    Citations: 7     Fields:    Translation:Humans
  40. Mancuso C, Izquierdo A, Slattery M, Becker KR, Plessow F, Thomas JJ, Eddy KT, Lawson EA, Misra M. Changes in appetite-regulating hormones following food intake are associated with changes in reported appetite and a measure of hedonic eating in girls and young women with anorexia nervosa. Psychoneuroendocrinology. 2020 03; 113:104556. PMID: 31918391.
    Citations: 8     Fields:    Translation:Humans
  41. Gehricke JG, Chan J, Farmer JG, Fenning RM, Steinberg-Epstein R, Misra M, Parker RA, Neumeyer AM. Physical activity rates in children and adolescents with autism spectrum disorder compared to the general population. Res Autism Spectr Disord. 2020 Feb; 70. PMID: 32322297.
    Citations: 2     
  42. Kambanis PE, Kuhnle MC, Wons OB, Jo JH, Keshishian AC, Hauser K, Becker KR, Franko DL, Misra M, Micali N, Lawson EA, Eddy KT, Thomas JJ. Prevalence and correlates of psychiatric comorbidities in children and adolescents with full and subthreshold avoidant/restrictive food intake disorder. Int J Eat Disord. 2020 02; 53(2):256-265. PMID: 31702051.
    Citations: 11     Fields:    Translation:Humans