Harvard Catalyst Profiles

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Nan McKenzie Laird, Ph.D.

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Research
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. R01MH059532 (LAIRD, NAN MCKENZIE) Sep 30, 1998 - Feb 29, 2012
    NIH/NIMH
    Family Based Tests of Association for Complex Diseases
    Role: Principal Investigator
  2. R01MH054693 (NORMAND, SHARON-LISE TERESA) Aug 1, 1996 - Dec 31, 2012
    NIH/NIMH
    Analysis of Multiple Informant Data in Psychiatry
    Role: Co-Principal Investigator
  3. T32MH017119 (KOENEN, KARESTAN C) Jul 1, 1983 - Jun 30, 2020
    NIH/NIMH
    Training Program in Psychiatric Genetics and Translational Research
    Role: Co-Principal Investigator
  4. N01DK032241 (LAIRD, NAN M) Mar 1, 1983
    NIH/NIDDK
    DATA FROM THE NATIONAL COOPERATIVE DIALYSIS STUDY
    Role: Principal Investigator
  5. R01GM029745 (FITZMAURICE, GARRETT M) Sep 1, 1981 - Jan 31, 2007
    NIH/NIGMS
    Methods for the Analysis of Longitudinal Data
    Role: Co-Principal Investigator

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Hecker J, Laird N, Lange C. A comparison of popular TDT-generalizations for family-based association analysis. Genet Epidemiol. 2019 04; 43(3):300-317. PMID: 30609057.
    Citations:    Fields:    
  2. Hecker J, Xu X, Townes FW, Loehlein Fier H, Corcoran C, Laird N, Lange C. Family-based tests for associating haplotypes with general phenotype data: Improving the FBAT-haplotype algorithm. Genet Epidemiol. 2018 02; 42(1):123-126. PMID: 29159827.
    Citations:    Fields:    Translation:Humans
  3. Sato Y, Gosho M, Nagashima K, Takahashi S, Ware JH, Laird NM. Statistical Methods in the Journal - An Update. N Engl J Med. 2017 03 16; 376(11):1086-1087. PMID: 28296608.
    Citations: 2     Fields:    
  4. Boueiz A, Lutz SM, Cho MH, Hersh CP, Bowler RP, Washko GR, Halper-Stromberg E, Bakke P, Gulsvik A, Laird NM, Beaty TH, Coxson HO, Crapo JD, Silverman EK, Castaldi PJ, DeMeo DL. Genome-Wide Association Study of the Genetic Determinants of Emphysema Distribution. Am J Respir Crit Care Med. 2017 03 15; 195(6):757-771. PMID: 27669027.
    Citations: 4     Fields:    Translation:Humans
  5. Hardin M, Cho MH, Sharma S, Glass K, Castaldi PJ, McDonald ML, Aschard H, Senter-Sylvia J, Tantisira K, Weiss ST, Hersh CP, Morrow JD, Lomas D, Agusti A, Bakke P, Gulsvik A, O'Connor GT, Dupuis J, Hokanson J, Crapo JD, Beaty TH, Laird N, Silverman EK, DeMeo DL. Sex-Based Genetic Association Study Identifies CELSR1 as a Possible Chronic Obstructive Pulmonary Disease Risk Locus among Women. Am J Respir Cell Mol Biol. 2017 03; 56(3):332-341. PMID: 27854507.
    Citations: 2     Fields:    Translation:Humans
  6. Qiao D, Lange C, Laird NM, Won S, Hersh CP, Morrow J, Hobbs BD, Lutz SM, Ruczinski I, Beaty TH, Silverman EK, Cho MH. Gene-based segregation method for identifying rare variants in family-based sequencing studies. Genet Epidemiol. 2017 05; 41(4):309-319. PMID: 28191685.
    Citations: 3     Fields:    Translation:Humans
  7. Hobbs BD, Parker MM, Chen H, Lao T, Hardin M, Qiao D, Hawrylkiewicz I, Sliwinski P, Yim JJ, Kim WJ, Kim DK, Castaldi PJ, Hersh CP, Morrow J, Celli BR, Pinto-Plata VM, Criner GJ, Marchetti N, Bueno R, Agustí A, Make BJ, Crapo JD, Calverley PM, Donner CF, Lomas DA, Wouters EF, Vestbo J, Paré PD, Levy RD, Rennard SI, Zhou X, Laird NM, Lin X, Beaty TH, Silverman EK, Cho MH. Exome Array Analysis Identifies a Common Variant in IL27 Associated with Chronic Obstructive Pulmonary Disease. Am J Respir Crit Care Med. 2016 07 01; 194(1):48-57. PMID: 26771213.
    Citations: 10     Fields:    Translation:Humans
  8. Lutz SM, Cho MH, Young K, Hersh CP, Castaldi PJ, McDonald ML, Regan E, Mattheisen M, DeMeo DL, Parker M, Foreman M, Make BJ, Jensen RL, Casaburi R, Lomas DA, Bhatt SP, Bakke P, Gulsvik A, Crapo JD, Beaty TH, Laird NM, Lange C, Hokanson JE, Silverman EK. A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry. BMC Genet. 2015 Dec 03; 16:138. PMID: 26634245.
    Citations: 12     Fields:    Translation:HumansCellsCTClinical Trials
  9. Cho MH, Castaldi PJ, Hersh CP, Hobbs BD, Barr RG, Tal-Singer R, Bakke P, Gulsvik A, San José Estépar R, Van Beek EJ, Coxson HO, Lynch DA, Washko GR, Laird NM, Crapo JD, Beaty TH, Silverman EK. A Genome-Wide Association Study of Emphysema and Airway Quantitative Imaging Phenotypes. Am J Respir Crit Care Med. 2015 Sep 01; 192(5):559-69. PMID: 26030696.
    Citations: 29     Fields:    Translation:Humans
  10. Zhou JJ, Cho MH, Lange C, Lutz S, Silverman EK, Laird NM. Integrating Multiple Correlated Phenotypes for Genetic Association Analysis by Maximizing Heritability. Hum Hered. 2015; 79(2):93-104. PMID: 26111731.
    Citations: 5     Fields:    Translation:Humans
  11. Yip WK, Fier H, DeMeo DL, Aryee M, Laird N, Lange C. A novel method for detecting association between DNA methylation and diseases using spatial information. Genet Epidemiol. 2014 Dec; 38(8):714-21. PMID: 25250875.
    Citations: 2     Fields:    Translation:HumansCells
  12. Chu JH, Hersh CP, Castaldi PJ, Cho MH, Raby BA, Laird N, Bowler R, Rennard S, Loscalzo J, Quackenbush J, Silverman EK. Analyzing networks of phenotypes in complex diseases: methodology and applications in COPD. BMC Syst Biol. 2014 Jun 25; 8:78. PMID: 24964944.
    Citations: 8     Fields:    Translation:Humans
  13. Zhou JJ, Yip WK, Cho MH, Qiao D, McDonald ML, Laird NM. A comparative analysis of family-based and population-based association tests using whole genome sequence data. BMC Proc. 2014; 8(Suppl 1 Genetic Analysis Workshop 18Vanessa Olmo):S33. PMID: 25519381.
    Citations: 4     
  14. Cho MH, McDonald ML, Zhou X, Mattheisen M, Castaldi PJ, Hersh CP, Demeo DL, Sylvia JS, Ziniti J, Laird NM, Lange C, Litonjua AA, Sparrow D, Casaburi R, Barr RG, Regan EA, Make BJ, Hokanson JE, Lutz S, Dudenkov TM, Farzadegan H, Hetmanski JB, Tal-Singer R, Lomas DA, Bakke P, Gulsvik A, Crapo JD, Silverman EK, Beaty TH. Risk loci for chronic obstructive pulmonary disease: a genome-wide association study and meta-analysis. Lancet Respir Med. 2014 Mar; 2(3):214-25. PMID: 24621683.
    Citations: 77     Fields:    Translation:Humans
  15. Zhou JJ, Cho MH, Castaldi PJ, Hersh CP, Silverman EK, Laird NM. Heritability of chronic obstructive pulmonary disease and related phenotypes in smokers. Am J Respir Crit Care Med. 2013 Oct 15; 188(8):941-7. PMID: 23972146.
    Citations: 23     Fields:    Translation:Humans
  16. Moreno-Macías H, Dockery DW, Schwartz J, Gold DR, Laird NM, Sienra-Monge JJ, Del Río-Navarro BE, Ramírez-Aguilar M, Barraza-Villarreal A, Li H, London SJ, Romieu I. Ozone exposure, vitamin C intake, and genetic susceptibility of asthmatic children in Mexico City: a cohort study. Respir Res. 2013 Feb 04; 14:14. PMID: 23379631.
    Citations: 11     Fields:    Translation:HumansPHPublic Health
  17. De G, Yip WK, Ionita-Laza I, Laird N. Rare variant analysis for family-based design. PLoS One. 2013; 8(1):e48495. PMID: 23341868.
    Citations: 39     Fields:    Translation:Humans
  18. Field AE, Sonneville KR, Micali N, Crosby RD, Swanson SA, Laird NM, Treasure J, Solmi F, Horton NJ. Prospective association of common eating disorders and adverse outcomes. Pediatrics. 2012 Aug; 130(2):e289-95. PMID: 22802602.
    Citations: 36     Fields:    Translation:Humans
  19. Adhikari K, AlChawa T, Ludwig K, Mangold E, Laird N, Lange C. Is it rare or common? Genet Epidemiol. 2012 Jul; 36(5):419-29. PMID: 22549767.
    Citations: 1     Fields:    Translation:Humans
  20. Yip WK, De G, Raby BA, Laird N. Identifying causal rare variants of disease through family-based analysis of Genetics Analysis Workshop 17 data set. BMC Proc. 2011 Nov 29; 5 Suppl 9:S21. PMID: 22373204.
    Citations: 10     
  21. Yan A, Laird NM, Li C. Identifying rare variants using a Bayesian regression approach. BMC Proc. 2011 Nov 29; 5 Suppl 9:S99. PMID: 22373362.
    Citations: 2     
  22. Sebro R, Lange C, Laird NM, Rogus JJ, Risch NJ. Differentiating population stratification from genotyping error using family data. Ann Hum Genet. 2012 Jan; 76(1):42-52. PMID: 22111716.
    Citations: 1     Fields:    Translation:Humans
  23. Castaldi PJ, Cho MH, Litonjua AA, Bakke P, Gulsvik A, Lomas DA, Anderson W, Beaty TH, Hokanson JE, Crapo JD, Laird N, Silverman EK. The association of genome-wide significant spirometric loci with chronic obstructive pulmonary disease susceptibility. Am J Respir Cell Mol Biol. 2011 Dec; 45(6):1147-53. PMID: 21659657.
    Citations: 29     Fields:    Translation:HumansCellsCTClinical Trials
  24. Yoon FB, Fitzmaurice GM, Lipsitz SR, Horton NJ, Laird NM, Normand SL. Alternative methods for testing treatment effects on the basis of multiple outcomes: simulation and case study. Stat Med. 2011 Jul 20; 30(16):1917-32. PMID: 21538986.
    Citations: 5     Fields:    Translation:Humans
  25. Javaras KN, Goldsmith HH, Laird NM. Estimating the effect of a predictor measured by two informants on a continuous outcome: a comparison of methods. Epidemiology. 2011 May; 22(3):390-9. PMID: 21403520.
    Citations: 1     Fields:    Translation:Humans
  26. Howrigan DP, Laird NM, Smoller JW, Devlin B, McQueen MB. Using linkage information to weight a genome-wide association of bipolar disorder. Am J Med Genet B Neuropsychiatr Genet. 2011 Jun; 156B(4):462-71. PMID: 21480485.
    Citations: 2     Fields:    Translation:HumansCells
  27. Hoffmann TJ, Vansteelandt S, Lange C, Silverman EK, DeMeo DL, Laird NM. Combining disease models to test for gene-environment interaction in nuclear families. Biometrics. 2011 Dec; 67(4):1260-70. PMID: 21401569.
    Citations: 1     Fields:    Translation:Humans
  28. Ionita-Laza I, Buxbaum JD, Laird NM, Lange C. A new testing strategy to identify rare variants with either risk or protective effect on disease. PLoS Genet. 2011 Feb 03; 7(2):e1001289. PMID: 21304886.
    Citations: 82     Fields:    Translation:Humans
  29. Sato Y, Yamamoto N, Kunitoh H, Ohe Y, Minami H, Laird NM, Katori N, Saito Y, Ohnami S, Sakamoto H, Sawada J, Saijo N, Yoshida T, Tamura T. Genome-wide association study on overall survival of advanced non-small cell lung cancer patients treated with carboplatin and paclitaxel. J Thorac Oncol. 2011 Jan; 6(1):132-8. PMID: 21079520.
    Citations: 12     Fields:    Translation:Humans
  30. Sinha SK, Laird NM, Fitzmaurice GM. Multivariate logistic regression with incomplete covariate and auxiliary information. J Multivar Anal. 2010 Nov 01; 101(10):2389-2397. PMID: 20953361.
    Citations: 1     
  31. Ionita-Laza I, Laird NM. On the optimal design of genetic variant discovery studies. Stat Appl Genet Mol Biol. 2010; 9:Article33. PMID: 20812911.
    Citations: 7     Fields:    Translation:Humans
  32. VanderWeele TJ, Laird NM. Tests for compositional epistasis under single interaction-parameter models. Ann Hum Genet. 2011 Jan; 75(1):146-56. PMID: 20726965.
    Citations: 9     Fields:    Translation:Humans
  33. Moreno-Macias H, Romieu I, London SJ, Laird NM. Gene-environment interaction tests for family studies with quantitative phenotypes: A review and extension to longitudinal measures. Hum Genomics. 2010 Jun; 4(5):302-26. PMID: 20650819.
    Citations: 3     Fields:    Translation:Humans
  34. Laird N, Fitzmaurice G, Ding X. Comments on 'Empirical vs natural weighting in random effects meta-analysis'. Stat Med. 2010 May 30; 29(12):1266-7; discussion 1272-81. PMID: 20499329.
    Citations: 3     Fields:    Translation:Humans
  35. Javaras KN, Hudson JI, Laird NM. Fitting ACE structural equation models to case-control family data. Genet Epidemiol. 2010 Apr; 34(3):238-45. PMID: 19918760.
    Citations: 5     Fields:    Translation:Humans
  36. Cho MH, Washko GR, Hoffmann TJ, Criner GJ, Hoffman EA, Martinez FJ, Laird N, Reilly JJ, Silverman EK. Cluster analysis in severe emphysema subjects using phenotype and genotype data: an exploratory investigation. Respir Res. 2010 Mar 16; 11:30. PMID: 20233420.
    Citations: 18     Fields:    Translation:Humans
  37. Fan J, Ionita-Laza I, McQueen MB, Devlin B, Purcell S, Faraone SV, Allen MH, Bowden CL, Calabrese JR, Fossey MD, Friedman ES, Gyulai L, Hauser P, Ketter TB, Marangell LB, Miklowitz DJ, Nierenberg AA, Patel JK, Sachs GS, Thase ME, Molay FB, Escamilla MA, Nimgaonkar VL, Sklar P, Laird NM, Smoller JW. Linkage disequilibrium mapping of the chromosome 6q21-22.31 bipolar I disorder susceptibility locus. Am J Med Genet B Neuropsychiatr Genet. 2010 Jan 05; 153B(1):29-37. PMID: 19308960.
    Citations: 5     Fields:    Translation:HumansCells
  38. Sato Y, Laird NM, Yoshida T. Biostatistic tools in pharmacogenomics--advances, challenges, potential. Curr Pharm Des. 2010; 16(20):2232-40. PMID: 20459388.
    Citations: 2     Fields:    Translation:Humans
  39. Louicharoen C, Patin E, Paul R, Nuchprayoon I, Witoonpanich B, Peerapittayamongkol C, Casademont I, Sura T, Laird NM, Singhasivanon P, Quintana-Murci L, Sakuntabhai A. Positively selected G6PD-Mahidol mutation reduces Plasmodium vivax density in Southeast Asians. Science. 2009 Dec 11; 326(5959):1546-9. PMID: 20007901.
    Citations: 58     Fields:    Translation:HumansAnimalsCells
  40. Hoffmann TJ, Lange C, Vansteelandt S, Raby BA, DeMeo DL, Silverman EK, Weiss ST, Laird NM. Parsing the effects of individual SNPs in candidate genes with family data. Hum Hered. 2010; 69(2):91-103. PMID: 19996607.
    Citations: 1     Fields:    Translation:Humans
  41. Hoffmann TJ, Lange C, Vansteelandt S, Laird NM. Gene-environment interaction tests for dichotomous traits in trios and sibships. Genet Epidemiol. 2009 Dec; 33(8):691-9. PMID: 19365860.
    Citations: 15     Fields:    Translation:Humans
  42. Sato Y, Laird N, Suganami H, Hamada C, Niki N, Yoshimura I, Yoshida T. Statistical screening method for genetic factors influencing susceptibility to common diseases in a two-stage genome-wide association study. Stat Appl Genet Mol Biol. 2009; 8:Article 46. PMID: 19954418.
    Citations:    Fields:    Translation:Humans
  43. Mansour HA, Talkowski ME, Wood J, Chowdari KV, McClain L, Prasad K, Montrose D, Fagiolini A, Friedman ES, Allen MH, Bowden CL, Calabrese J, El-Mallakh RS, Escamilla M, Faraone SV, Fossey MD, Gyulai L, Loftis JM, Hauser P, Ketter TA, Marangell LB, Miklowitz DJ, Nierenberg AA, Patel J, Sachs GS, Sklar P, Smoller JW, Laird N, Keshavan M, Thase ME, Axelson D, Birmaher B, Lewis D, Monk T, Frank E, Kupfer DJ, Devlin B, Nimgaonkar VL. Association study of 21 circadian genes with bipolar I disorder, schizoaffective disorder, and schizophrenia. Bipolar Disord. 2009 Nov; 11(7):701-10. PMID: 19839995.
    Citations: 50     Fields:    Translation:Humans
  44. Heid IM, Huth C, Loos RJ, Kronenberg F, Adamkova V, Anand SS, Ardlie K, Biebermann H, Bjerregaard P, Boeing H, Bouchard C, Ciullo M, Cooper JA, Corella D, Dina C, Engert JC, Fisher E, Francès F, Froguel P, Hebebrand J, Hegele RA, Hinney A, Hoehe MR, Hu FB, Hubacek JA, Humphries SE, Hunt SC, Illig T, Järvelin MR, Kaakinen M, Kollerits B, Krude H, Kumar J, Lange LA, Langer B, Li S, Luchner A, Lyon HN, Meyre D, Mohlke KL, Mooser V, Nebel A, Nguyen TT, Paulweber B, Perusse L, Qi L, Rankinen T, Rosskopf D, Schreiber S, Sengupta S, Sorice R, Suk A, Thorleifsson G, Thorsteinsdottir U, Völzke H, Vimaleswaran KS, Wareham NJ, Waterworth D, Yusuf S, Lindgren C, McCarthy MI, Lange C, Hirschhorn JN, Laird N, Wichmann HE. Meta-analysis of the INSIG2 association with obesity including 74,345 individuals: does heterogeneity of estimates relate to study design? PLoS Genet. 2009 Oct; 5(10):e1000694. PMID: 19851442.
    Citations: 22     Fields:    Translation:Humans
  45. Sangrajrang S, Sato Y, Sakamoto H, Ohnami S, Laird NM, Khuhaprema T, Brennan P, Boffetta P, Yoshida T. Genetic polymorphisms of estrogen metabolizing enzyme and breast cancer risk in Thai women. Int J Cancer. 2009 Aug 15; 125(4):837-43. PMID: 19415745.
    Citations: 29     Fields:    Translation:Humans
  46. Javaras KN, Laird NM, Hudson JI, Ripley BD. Estimating disease prevalence using relatives of case and control probands. Biometrics. 2010 Mar; 66(1):214-21. PMID: 19459833.
    Citations: 5     Fields:    Translation:Humans
  47. Ding X, Laird N. Family-Based Association Tests with longitudinal measurements: handling missing data. Hum Hered. 2009; 68(2):98-105. PMID: 19365136.
    Citations: 1     Fields:    Translation:Humans
  48. Hoffmann TJ, Laird NM. fgui: A Method for Automatically Creating Graphical User Interfaces for Command-Line R Packages. J Stat Softw. 2009 Apr 01; 30(2). PMID: 21625291.
    Citations: 4     
  49. Ding X, Weiss S, Raby B, Lange C, Laird NM. Impact of population stratification on family-based association tests with longitudinal measurements. Stat Appl Genet Mol Biol. 2009; 8:Article 17. PMID: 19222384.
    Citations: 2     Fields:    Translation:Humans
  50. Murphy JM, Horton NJ, Burke JD, Monson RR, Laird NM, Lesage A, Sobol AM. Obesity and weight gain in relation to depression: findings from the Stirling County Study. Int J Obes (Lond). 2009 Mar; 33(3):335-41. PMID: 19139752.
    Citations: 18     Fields:    Translation:Humans
  51. Sato Y, Laird NM, Nagashima K, Kato R, Hamano T, Yafune A, Kaniwa N, Saito Y, Sugiyama E, Kim SR, Furuse J, Ishii H, Ueno H, Okusaka T, Saijo N, Sawada JI, Yoshida T. A new statistical screening approach for finding pharmacokinetics-related genes in genome-wide studies. Pharmacogenomics J. 2009 Apr; 9(2):137-46. PMID: 19104505.
    Citations: 2     Fields:    Translation:Humans
  52. Lasky-Su J, Anney RJ, Neale BM, Franke B, Zhou K, Maller JB, Vasquez AA, Chen W, Asherson P, Buitelaar J, Banaschewski T, Ebstein R, Gill M, Miranda A, Mulas F, Oades RD, Roeyers H, Rothenberger A, Sergeant J, Sonuga-Barke E, Steinhausen HC, Taylor E, Daly M, Laird N, Lange C, Faraone SV. Genome-wide association scan of the time to onset of attention deficit hyperactivity disorder. Am J Med Genet B Neuropsychiatr Genet. 2008 Dec 05; 147B(8):1355-8. PMID: 18937294.
    Citations: 36     Fields:    Translation:Humans
  53. Neale BM, Lasky-Su J, Anney R, Franke B, Zhou K, Maller JB, Vasquez AA, Asherson P, Chen W, Banaschewski T, Buitelaar J, Ebstein R, Gill M, Miranda A, Oades RD, Roeyers H, Rothenberger A, Sergeant J, Steinhausen HC, Sonuga-Barke E, Mulas F, Taylor E, Laird N, Lange C, Daly M, Faraone SV. Genome-wide association scan of attention deficit hyperactivity disorder. Am J Med Genet B Neuropsychiatr Genet. 2008 Dec 05; 147B(8):1337-44. PMID: 18980221.
    Citations: 91     Fields:    Translation:Humans
  54. Lasky-Su J, Neale BM, Franke B, Anney RJ, Zhou K, Maller JB, Vasquez AA, Chen W, Asherson P, Buitelaar J, Banaschewski T, Ebstein R, Gill M, Miranda A, Mulas F, Oades RD, Roeyers H, Rothenberger A, Sergeant J, Sonuga-Barke E, Steinhausen HC, Taylor E, Daly M, Laird N, Lange C, Faraone SV. Genome-wide association scan of quantitative traits for attention deficit hyperactivity disorder identifies novel associations and confirms candidate gene associations. Am J Med Genet B Neuropsychiatr Genet. 2008 Dec 05; 147B(8):1345-54. PMID: 18821565.
    Citations: 122     Fields:    Translation:Humans
  55. Bertram L, Lange C, Mullin K, Parkinson M, Hsiao M, Hogan MF, Schjeide BM, Hooli B, Divito J, Ionita I, Jiang H, Laird N, Moscarillo T, Ohlsen KL, Elliott K, Wang X, Hu-Lince D, Ryder M, Murphy A, Wagner SL, Blacker D, Becker KD, Tanzi RE. Genome-wide association analysis reveals putative Alzheimer's disease susceptibility loci in addition to APOE. Am J Hum Genet. 2008 Nov; 83(5):623-32. PMID: 18976728.
    Citations: 151     Fields:    Translation:HumansCells
  56. Ding X, Lange C, Xu X, Laird N. New powerful approaches for family-based association tests with longitudinal measurements. Ann Hum Genet. 2009 Jan; 73(1):74-83. PMID: 18798838.
    Citations: 5     Fields:    Translation:Humans
  57. Ionita-Laza I, Laird NM, Raby BA, Weiss ST, Lange C. On the frequency of copy number variants. Bioinformatics. 2008 Oct 15; 24(20):2350-5. PMID: 18689430.
    Citations: 3     Fields:    Translation:Humans
  58. Field AE, Javaras KM, Aneja P, Kitos N, Camargo CA, Taylor CB, Laird NM. Family, peer, and media predictors of becoming eating disordered. Arch Pediatr Adolesc Med. 2008 Jun; 162(6):574-9. PMID: 18524749.
    Citations: 33     Fields:    Translation:Humans
  59. Hudson JI, Javaras KN, Laird NM, VanderWeele TJ, Pope HG, Hernán MA. A structural approach to the familial coaggregation of disorders. Epidemiology. 2008 May; 19(3):431-9. PMID: 18379420.
    Citations: 11     Fields:    Translation:Humans
  60. Ionita-Laza I, Perry GH, Raby BA, Klanderman B, Lee C, Laird NM, Weiss ST, Lange C. On the analysis of copy-number variations in genome-wide association studies: a translation of the family-based association test. Genet Epidemiol. 2008 Apr; 32(3):273-84. PMID: 18228561.
    Citations: 32     Fields:    Translation:Humans
  61. Lasky-Su J, Lyon HN, Emilsson V, Heid IM, Molony C, Raby BA, Lazarus R, Klanderman B, Soto-Quiros ME, Avila L, Silverman EK, Thorleifsson G, Thorsteinsdottir U, Kronenberg F, Vollmert C, Illig T, Fox CS, Levy D, Laird N, Ding X, McQueen MB, Butler J, Ardlie K, Papoutsakis C, Dedoussis G, O'Donnell CJ, Wichmann HE, Celedón JC, Schadt E, Hirschhorn J, Weiss ST, Stefansson K, Lange C. On the replication of genetic associations: timing can be everything! Am J Hum Genet. 2008 Apr; 82(4):849-58. PMID: 18387595.
    Citations: 61     Fields:    Translation:Humans
  62. Rakovski CS, Weiss ST, Laird NM, Lange C. FBAT-SNP-PC: an approach for multiple markers and single trait in family-based association tests. Hum Hered. 2008; 66(2):122-6. PMID: 18382091.
    Citations: 1     Fields:    Translation:Humans
  63. Murphy JM, Burke JD, Monson RR, Horton NJ, Laird NM, Lesage A, Sobol AM, Leighton AH. Mortality associated with depression: a forty-year perspective from the Stirling County Study. Soc Psychiatry Psychiatr Epidemiol. 2008 Aug; 43(8):594-601. PMID: 18327523.
    Citations: 13     Fields:    Translation:Humans
  64. Javaras KN, Laird NM, Reichborn-Kjennerud T, Bulik CM, Pope HG, Hudson JI. Familiality and heritability of binge eating disorder: results of a case-control family study and a twin study. Int J Eat Disord. 2008 Mar; 41(2):174-9. PMID: 18095307.
    Citations: 32     Fields:    Translation:Humans
  65. Javaras KN, Pope HG, Lalonde JK, Roberts JL, Nillni YI, Laird NM, Bulik CM, Crow SJ, McElroy SL, Walsh BT, Tsuang MT, Rosenthal NR, Hudson JI. Co-occurrence of binge eating disorder with psychiatric and medical disorders. J Clin Psychiatry. 2008 Feb; 69(2):266-73. PMID: 18348600.
    Citations: 54     Fields:    Translation:Humans
  66. Lasky-Su J, Lange C, Biederman J, Tsuang M, Doyle AE, Smoller JW, Laird N, Faraone S. Family-based association analysis of a statistically derived quantitative traits for ADHD reveal an association in DRD4 with inattentive symptoms in ADHD individuals. Am J Med Genet B Neuropsychiatr Genet. 2008 Jan 05; 147B(1):100-6. PMID: 17579349.
    Citations: 12     Fields:    Translation:Humans
  67. Laird NM, Lange C. Family-based methods for linkage and association analysis. Adv Genet. 2008; 60:219-52. PMID: 18358323.
    Citations: 24     Fields:    Translation:Humans
  68. Schneiter K, Degnan JH, Corcoran C, Xu X, Laird N. EFBAT: exact family-based association tests. BMC Genet. 2007 Dec 20; 8:86. PMID: 18096066.
    Citations: 1     Fields:    Translation:HumansCells
  69. Ionita-Laza I, McQueen MB, Laird NM, Lange C. Genomewide weighted hypothesis testing in family-based association studies, with an application to a 100K scan. Am J Hum Genet. 2007 Sep; 81(3):607-14. PMID: 17701906.
    Citations: 45     Fields:    Translation:Humans
  70. Harezlak J, Coull BA, Laird NM, Magari SR, Christiani DC. Penalized solutions to functional regression problems. Comput Stat Data Anal. 2007 Jun 15; 51(10):4911-4925. PMID: 18552972.
    Citations: 3     
  71. Lasky-Su J, Biederman J, Laird N, Tsuang M, Doyle AE, Smoller JW, Lange C, Faraone SV. Evidence for an association of the dopamine D5 receptor gene on age at onset of attention deficit hyperactivity disorder. Ann Hum Genet. 2007 Sep; 71(Pt 5):648-59. PMID: 17501935.
    Citations: 6     Fields:    Translation:Humans
  72. Harezlak J, Naumova E, Laird NM. LongCriSP: a test for bump hunting in longitudinal data. Stat Med. 2007 Mar 15; 26(6):1383-97. PMID: 16850452.
    Citations:    Fields:    Translation:Humans
  73. Lyon HN, Emilsson V, Hinney A, Heid IM, Lasky-Su J, Zhu X, Thorleifsson G, Gunnarsdottir S, Walters GB, Thorsteinsdottir U, Kong A, Gulcher J, Nguyen TT, Scherag A, Pfeufer A, Meitinger T, Brönner G, Rief W, Soto-Quiros ME, Avila L, Klanderman B, Raby BA, Silverman EK, Weiss ST, Laird N, Ding X, Groop L, Tuomi T, Isomaa B, Bengtsson K, Butler JL, Cooper RS, Fox CS, O'Donnell CJ, Vollmert C, Celedón JC, Wichmann HE, Hebebrand J, Stefansson K, Lange C, Hirschhorn JN. The association of a SNP upstream of INSIG2 with body mass index is reproduced in several but not all cohorts. PLoS Genet. 2007 Apr 27; 3(4):e61. PMID: 17465681.
    Citations: 61     Fields:    Translation:Humans
  74. McQueen MB, Weiss S, Laird NM, Lange C. On the parsing of statistical information in family-based association testing. Nat Genet. 2007 Mar; 39(3):281-2. PMID: 17325672.
    Citations: 1     Fields:    Translation:Humans
  75. Litman HJ, Horton NJ, Hernández B, Laird NM. Incorporating missingness for estimation of marginal regression models with multiple source predictors. Stat Med. 2007 Feb 28; 26(5):1055-68. PMID: 16755531.
    Citations: 4     Fields:    Translation:Humans
  76. Lasky-Su J, Faraone SV, Lange C, Tsuang MT, Doyle AE, Smoller JW, Laird NM, Biederman J. A study of how socioeconomic status moderates the relationship between SNPs encompassing BDNF and ADHD symptom counts in ADHD families. Behav Genet. 2007 May; 37(3):487-97. PMID: 17216343.
    Citations: 14     Fields:    Translation:Humans
  77. Rakovski CS, Xu X, Lazarus R, Blacker D, Laird NM. A new multimarker test for family-based association studies. Genet Epidemiol. 2007 Jan; 31(1):9-17. PMID: 17086514.
    Citations: 22     Fields:    Translation:Humans
  78. Van Steen K, Laird NM, Markel P, Molenberghs G. Approaches to handling incomplete data in family-based association testing. Ann Hum Genet. 2007 Mar; 71(Pt 2):141-51. PMID: 17096676.
    Citations: 1     Fields:    Translation:Humans
  79. Xu X, Rakovski C, Xu X, Laird N. An efficient family-based association test using multiple markers. Genet Epidemiol. 2006 Nov; 30(7):620-6. PMID: 16868964.
    Citations: 15     Fields:    Translation:Humans
  80. Litman HJ, Horton NJ, Murphy JM, Laird NM. Marginal regression models with a time to event outcome and discrete multiple source predictors. Lifetime Data Anal. 2006 Sep; 12(3):249-65. PMID: 17021951.
    Citations:    Fields:    Translation:Humans
  81. Laird NM, Lange C. Family-based designs in the age of large-scale gene-association studies. Nat Rev Genet. 2006 May; 7(5):385-94. PMID: 16619052.
    Citations: 131     Fields:    Translation:Humans
  82. Herbert A, Gerry NP, McQueen MB, Heid IM, Pfeufer A, Illig T, Wichmann HE, Meitinger T, Hunter D, Hu FB, Colditz G, Hinney A, Hebebrand J, Koberwitz K, Zhu X, Cooper R, Ardlie K, Lyon H, Hirschhorn JN, Laird NM, Lenburg ME, Lange C, Christman MF. A common genetic variant is associated with adult and childhood obesity. Science. 2006 Apr 14; 312(5771):279-83. PMID: 16614226.
    Citations: 221     Fields:    Translation:Humans
  83. McQueen MB, Blacker D, Laird NM. Variance calculations for identity-by-descent estimation. Am J Hum Genet. 2006 Jun; 78(6):914-21. PMID: 16685643.
    Citations: 2     Fields:    Translation:Humans
  84. Wang L, Wang X, Laird N, Zuckerman B, Stubblefield P, Xu X. Polymorphism in maternal LRP8 gene is associated with fetal growth. Am J Hum Genet. 2006 May; 78(5):770-777. PMID: 16642433.
    Citations: 19     Fields:    Translation:Humans
  85. Hudson JI, Lalonde JK, Berry JM, Pindyck LJ, Bulik CM, Crow SJ, McElroy SL, Laird NM, Tsuang MT, Walsh BT, Rosenthal NR, Pope HG. Binge-eating disorder as a distinct familial phenotype in obese individuals. Arch Gen Psychiatry. 2006 Mar; 63(3):313-9. PMID: 16520437.
    Citations: 38     Fields:    Translation:Humans
  86. Hsu YH, Venners SA, Terwedow HA, Feng Y, Niu T, Li Z, Laird N, Brain JD, Cummings SR, Bouxsein ML, Rosen CJ, Xu X. Relation of body composition, fat mass, and serum lipids to osteoporotic fractures and bone mineral density in Chinese men and women. Am J Clin Nutr. 2006 Jan; 83(1):146-54. PMID: 16400063.
    Citations: 134     Fields:    Translation:Humans
  87. McQueen MB, Murphy A, Kraft P, Su J, Lazarus R, Laird NM, Lange C, Van Steen K. Comparison of linkage and association strategies for quantitative traits using the COGA dataset. BMC Genet. 2005 Dec 30; 6 Suppl 1:S96. PMID: 16451712.
    Citations:    Fields:    Translation:HumansCells
  88. Murphy A, McQueen MB, Su J, Kraft P, Lazarus R, Laird NM, Lange C, Van Steen K. Genomic screening in family-based association testing. BMC Genet. 2005 Dec 30; 6 Suppl 1:S115. PMID: 16451572.
    Citations: 2     Fields:    Translation:Humans
  89. Field AE, Austin SB, Striegel-Moore R, Taylor CB, Camargo CA, Laird N, Colditz G. Weight concerns and weight control behaviors of adolescents and their mothers. Arch Pediatr Adolesc Med. 2005 Dec; 159(12):1121-6. PMID: 16330734.
    Citations: 10     Fields:    Translation:Humans
  90. Schneiter K, Laird N, Corcoran C. Exact family-based association tests for biallelic data. Genet Epidemiol. 2005 Nov; 29(3):185-94. PMID: 16094642.
    Citations: 4     Fields:    Translation:Humans
  91. Hsu YH, Niu T, Terwedow HA, Xu X, Feng Y, Li Z, Brain JD, Rosen CJ, Laird N, Xu X. Variation in genes involved in the RANKL/RANK/OPG bone remodeling pathway are associated with bone mineral density at different skeletal sites in men. Hum Genet. 2006 Jan; 118(5):568-77. PMID: 16249885.
    Citations: 34     Fields:    Translation:Humans
  92. McQueen MB, Devlin B, Faraone SV, Nimgaonkar VL, Sklar P, Smoller JW, Abou Jamra R, Albus M, Bacanu SA, Baron M, Barrett TB, Berrettini W, Blacker D, Byerley W, Cichon S, Coryell W, Craddock N, Daly MJ, Depaulo JR, Edenberg HJ, Foroud T, Gill M, Gilliam TC, Hamshere M, Jones I, Jones L, Juo SH, Kelsoe JR, Lambert D, Lange C, Lerer B, Liu J, Maier W, Mackinnon JD, McInnis MG, McMahon FJ, Murphy DL, Nothen MM, Nurnberger JI, Pato CN, Pato MT, Potash JB, Propping P, Pulver AE, Rice JP, Rietschel M, Scheftner W, Schumacher J, Segurado R, Van Steen K, Xie W, Zandi PP, Laird NM. Combined analysis from eleven linkage studies of bipolar disorder provides strong evidence of susceptibility loci on chromosomes 6q and 8q. Am J Hum Genet. 2005 Oct; 77(4):582-95. PMID: 16175504.
    Citations: 68     Fields:    Translation:HumansCells
  93. Smoller JW, Yamaki LH, Fagerness JA, Biederman J, Racette S, Laird NM, Kagan J, Snidman N, Faraone SV, Hirshfeld-Becker D, Tsuang MT, Slaugenhaupt SA, Rosenbaum JF, Sklar PB. The corticotropin-releasing hormone gene and behavioral inhibition in children at risk for panic disorder. Biol Psychiatry. 2005 Jun 15; 57(12):1485-92. PMID: 15953484.
    Citations: 40     Fields:    Translation:Humans
  94. Van Steen K, McQueen MB, Herbert A, Raby B, Lyon H, Demeo DL, Murphy A, Su J, Datta S, Rosenow C, Christman M, Silverman EK, Laird NM, Weiss ST, Lange C. Genomic screening and replication using the same data set in family-based association testing. Nat Genet. 2005 Jul; 37(7):683-91. PMID: 15937480.
    Citations: 85     Fields:    Translation:Humans
  95. Hersh CP, Demeo DL, Lange C, Litonjua AA, Reilly JJ, Kwiatkowski D, Laird N, Sylvia JS, Sparrow D, Speizer FE, Weiss ST, Silverman EK. Attempted replication of reported chronic obstructive pulmonary disease candidate gene associations. Am J Respir Cell Mol Biol. 2005 Jul; 33(1):71-8. PMID: 15817713.
    Citations: 55     Fields:    Translation:HumansCells
  96. Abecasis G, Cox N, Daly MJ, Kruglyak L, Laird N, Markianos K, Patterson N. No bias in linkage analysis. Am J Hum Genet. 2004 Oct; 75(4):722-3; author reply 723-7. PMID: 15338460.
    Citations: 1     Fields:    Translation:Humans
  97. Lange C, van Steen K, Andrew T, Lyon H, DeMeo DL, Raby B, Murphy A, Silverman EK, MacGregor A, Weiss ST, Laird NM. A family-based association test for repeatedly measured quantitative traits adjusting for unknown environmental and/or polygenic effects. Stat Appl Genet Mol Biol. 2004; 3:Article17. PMID: 16646795.
    Citations: 47     Fields:    
  98. Celedón JC, Lange C, Raby BA, Litonjua AA, Palmer LJ, DeMeo DL, Reilly JJ, Kwiatkowski DJ, Chapman HA, Laird N, Sylvia JS, Hernandez M, Speizer FE, Weiss ST, Silverman EK. The transforming growth factor-beta1 (TGFB1) gene is associated with chronic obstructive pulmonary disease (COPD). Hum Mol Genet. 2004 Aug 01; 13(15):1649-56. PMID: 15175276.
    Citations: 77     Fields:    Translation:HumansCells
  99. Feng Y, Niu T, Xing H, Xu X, Chen C, Peng S, Wang L, Laird N, Xu X. A common haplotype of the nicotine acetylcholine receptor alpha 4 subunit gene is associated with vulnerability to nicotine addiction in men. Am J Hum Genet. 2004 Jul; 75(1):112-21. PMID: 15154117.
    Citations: 76     Fields:    Translation:Humans
  100. Murphy JM, Horton NJ, Laird NM, Monson RR, Sobol AM, Leighton AH. Anxiety and depression: a 40-year perspective on relationships regarding prevalence, distribution, and comorbidity. Acta Psychiatr Scand. 2004 May; 109(5):355-75. PMID: 15049772.
    Citations: 18     Fields:    Translation:Humans
  101. Brennan TA, Leape LL, Laird NM, Hebert L, Localio AR, Lawthers AG, Newhouse JP, Weiler PC, Hiatt HH. Incidence of adverse events and negligence in hospitalized patients: results of the Harvard Medical Practice Study I. 1991. Qual Saf Health Care. 2004 Apr; 13(2):145-51; discussion 151-2. PMID: 15069223.
    Citations: 61     Fields:    Translation:Humans
  102. Hao K, Wang X, Niu T, Xu X, Li A, Chang W, Wang L, Li G, Laird N, Xu X. A candidate gene association study on preterm delivery: application of high-throughput genotyping technology and advanced statistical methods. Hum Mol Genet. 2004 Apr 01; 13(7):683-91. PMID: 14976157.
    Citations: 25     Fields:    Translation:Humans
  103. Field AE, Manson JE, Laird N, Williamson DF, Willett WC, Colditz GA. Weight cycling and the risk of developing type 2 diabetes among adult women in the United States. Obes Res. 2004 Feb; 12(2):267-74. PMID: 14981219.
    Citations: 23     Fields:    Translation:Humans
  104. Lyon H, Lange C, Lake S, Silverman EK, Randolph AG, Kwiatkowski D, Raby BA, Lazarus R, Weiland KM, Laird N, Weiss ST. IL10 gene polymorphisms are associated with asthma phenotypes in children. Genet Epidemiol. 2004 Feb; 26(2):155-65. PMID: 14748015.
    Citations: 33     Fields:    Translation:HumansCells
  105. Lange C, DeMeo D, Silverman EK, Weiss ST, Laird NM. PBAT: tools for family-based association studies. Am J Hum Genet. 2004 Feb; 74(2):367-9. PMID: 14740322.
    Citations: 122     Fields:    Translation:Humans
  106. Lange C, Blacker D, Laird NM. Family-based association tests for survival and times-to-onset analysis. Stat Med. 2004 Jan 30; 23(2):179-89. PMID: 14716720.
    Citations: 16     Fields:    Translation:Humans
  107. Lake SL, Laird NM. Tests of gene-environment interaction for case-parent triads with general environmental exposures. Ann Hum Genet. 2004 Jan; 68(Pt 1):55-64. PMID: 14748830.
    Citations: 21     Fields:    Translation:HumansPHPublic Health
  108. Horvath S, Xu X, Lake SL, Silverman EK, Weiss ST, Laird NM. Family-based tests for associating haplotypes with general phenotype data: application to asthma genetics. Genet Epidemiol. 2004 Jan; 26(1):61-9. PMID: 14691957.
    Citations: 157     Fields:    Translation:Humans
  109. Hao K, Xu X, Laird N, Wang X, Xu X. Power estimation of multiple SNP association test of case-control study and application. Genet Epidemiol. 2004 Jan; 26(1):22-30. PMID: 14691954.
    Citations: 14     Fields:    Translation:Humans
  110. Smoller JW, Rosenbaum JF, Biederman J, Kennedy J, Dai D, Racette SR, Laird NM, Kagan J, Snidman N, Hirshfeld-Becker D, Tsuang MT, Sklar PB, Slaugenhaupt SA. Association of a genetic marker at the corticotropin-releasing hormone locus with behavioral inhibition. Biol Psychiatry. 2003 Dec 15; 54(12):1376-81. PMID: 14675801.
    Citations: 31     Fields:    Translation:Humans
  111. Silverman EK, Kwiatkowski DJ, Sylvia JS, Lazarus R, Drazen JM, Lange C, Laird NM, Weiss ST. Family-based association analysis of beta2-adrenergic receptor polymorphisms in the childhood asthma management program. J Allergy Clin Immunol. 2003 Nov; 112(5):870-6. PMID: 14610472.
    Citations: 35     Fields:    Translation:HumansCTClinical Trials
  112. Field AE, Laird N, Steinberg E, Fallon E, Semega-Janneh M, Yanovski JA. Which metric of relative weight best captures body fatness in children? Obes Res. 2003 Nov; 11(11):1345-52. PMID: 14627755.
    Citations: 23     Fields:    Translation:Humans
  113. Mangweth B, Hudson JI, Pope HG, Hausmann A, De Col C, Laird NM, Beibl W, Tsuang MT. Family study of the aggregation of eating disorders and mood disorders. Psychol Med. 2003 Oct; 33(7):1319-23. PMID: 14580085.
    Citations: 8     Fields:    Translation:Humans
  114. Lange C, DeMeo D, Silverman EK, Weiss ST, Laird NM. Using the noninformative families in family-based association tests: a powerful new testing strategy. Am J Hum Genet. 2003 Oct; 73(4):801-11. PMID: 14502464.
    Citations: 33     Fields:    Translation:Humans
  115. Saunders AJ, Bertram L, Mullin K, Sampson AJ, Latifzai K, Basu S, Jones J, Kinney D, MacKenzie-Ingano L, Yu S, Albert MS, Moscarillo TJ, Go RC, Bassett SS, Daly MJ, Laird NM, Wang X, Velicelebi G, Wagner SL, Becker DK, Tanzi RE, Blacker D. Genetic association of Alzheimer's disease with multiple polymorphisms in alpha-2-macroglobulin. Hum Mol Genet. 2003 Nov 01; 12(21):2765-76. PMID: 12966032.
    Citations: 15     Fields:    Translation:HumansCells
  116. Murphy JM, Horton NJ, Monson RR, Laird NM, Sobol AM, Leighton AH. Cigarette smoking in relation to depression: historical trends from the Stirling County Study. Am J Psychiatry. 2003 Sep; 160(9):1663-9. PMID: 12944343.
    Citations: 42     Fields:    Translation:Humans
  117. Slasor P, Laird N. Joint models for efficient estimation in proportional hazards regression models. Stat Med. 2003 Jul 15; 22(13):2137-48. PMID: 12820279.
    Citations: 1     Fields:    Translation:HumansCells
  118. Laird NM, Cuenco KT. Regression methods for assessing familial aggregation of disease. Stat Med. 2003 May 15; 22(9):1447-55. PMID: 12704608.
    Citations: 4     Fields:    Translation:HumansPHPublic Health
  119. Yang Q, Xu X, Laird N. Power evaluations for family-based tests of association with incomplete parental genotypes. Genetics. 2003 May; 164(1):399-406. PMID: 12750350.
    Citations: 4     Fields:    
  120. Lange C, Silverman EK, Xu X, Weiss ST, Laird NM. A multivariate family-based association test using generalized estimating equations: FBAT-GEE. Biostatistics. 2003 Apr; 4(2):195-206. PMID: 12925516.
    Citations: 81     Fields:    Translation:Humans
  121. Hudson JI, Mangweth B, Pope HG, De Col C, Hausmann A, Gutweniger S, Laird NM, Biebl W, Tsuang MT. Family study of affective spectrum disorder. Arch Gen Psychiatry. 2003 Feb; 60(2):170-7. PMID: 12578434.
    Citations: 29     Fields:    Translation:Humans
  122. Lake SL, Lyon H, Tantisira K, Silverman EK, Weiss ST, Laird NM, Schaid DJ. Estimation and tests of haplotype-environment interaction when linkage phase is ambiguous. Hum Hered. 2003; 55(1):56-65. PMID: 12890927.
    Citations: 151     Fields:    Translation:Humans
  123. Lange C, DeMeo DL, Laird NM. Power and design considerations for a general class of family-based association tests: quantitative traits. Am J Hum Genet. 2002 Dec; 71(6):1330-41. PMID: 12454799.
    Citations: 56     Fields:    Translation:Humans
  124. DeMeo DL, Lange C, Silverman EK, Senter JM, Drazen JM, Barth MJ, Laird N, Weiss ST. Univariate and multivariate family-based association analysis of the IL-13 ARG130GLN polymorphism in the Childhood Asthma Management Program. Genet Epidemiol. 2002 Nov; 23(4):335-48. PMID: 12432502.
    Citations: 21     Fields:    Translation:HumansCells
  125. Lange C, Laird NM. Power calculations for a general class of family-based association tests: dichotomous traits. Am J Hum Genet. 2002 Sep; 71(3):575-84. PMID: 12181775.
    Citations: 37     Fields:    Translation:Humans
  126. Lange C, Laird NM. On a general class of conditional tests for family-based association studies in genetics: the asymptotic distribution, the conditional power, and optimality considerations. Genet Epidemiol. 2002 Aug; 23(2):165-80. PMID: 12214309.
    Citations: 45     Fields:    Translation:Humans
  127. Murphy JM, Nierenberg AA, Laird NM, Monson RR, Sobol AM, Leighton AH. Incidence of major depression: prediction from subthreshold categories in the Stirling County Study. J Affect Disord. 2002 Apr; 68(2-3):251-9. PMID: 12063153.
    Citations: 7     Fields:    Translation:Humans
  128. Pauler DK, Laird NM. Non-linear hierarchical models for monitoring compliance. Stat Med. 2002 Jan 30; 21(2):219-29. PMID: 11782061.
    Citations: 1     Fields:    Translation:Humans
  129. Murphy JM, Nierenberg AA, Monson RR, Laird NM, Sobol AM, Leighton AH. Self-disparagement as feature and forerunner of depression: findings from the Stirling County Study. Compr Psychiatry. 2002 Jan-Feb; 43(1):13-21. PMID: 11788914.
    Citations: 2     Fields:    Translation:Humans
  130. Daskalakis C, Laird NM, Murphy JM. Regression analysis of multiple-source longitudinal outcomes: a "Stirling County" depression study. Am J Epidemiol. 2002 Jan 01; 155(1):88-94. PMID: 11772789.
    Citations: 2     Fields:    Translation:Humans
  131. Naumova EN, Must A, Laird NM. Tutorial in Biostatistics: Evaluating the impact of 'critical periods' in longitudinal studies of growth using piecewise mixed effects models. Int J Epidemiol. 2001 Dec; 30(6):1332-41. PMID: 11821342.
    Citations: 44     Fields:    Translation:Humans
  132. Horton NJ, Laird NM, Murphy JM, Monson RR, Sobol AM, Leighton AH. Multiple informants: mortality associated with psychiatric disorders in the Stirling County Study. Am J Epidemiol. 2001 Oct 01; 154(7):649-56. PMID: 11581099.
    Citations: 18     Fields:    Translation:Humans
  133. Field AE, Coakley EH, Must A, Spadano JL, Laird N, Dietz WH, Rimm E, Colditz GA. Impact of overweight on the risk of developing common chronic diseases during a 10-year period. Arch Intern Med. 2001 Jul 09; 161(13):1581-6. PMID: 11434789.
    Citations: 267     Fields:    Translation:Humans
  134. Fitzmaurice GM, Laird NM, Shneyer L. An alternative parameterization of the general linear mixture model for longitudinal data with non-ignorable drop-outs. Stat Med. 2001 Apr 15; 20(7):1009-21. PMID: 11276032.
    Citations: 11     Fields:    Translation:HumansCTClinical Trials
  135. Smoller JW, Rosenbaum JF, Biederman J, Susswein LS, Kennedy J, Kagan J, Snidman N, Laird N, Tsuang MT, Faraone SV, Schwarz A, Slaugenhaupt SA. Genetic association analysis of behavioral inhibition using candidate loci from mouse models. Am J Med Genet. 2001 Apr 08; 105(3):226-35. PMID: 11353440.
    Citations: 13     Fields:    Translation:HumansAnimals
  136. Horvath S, Xu X, Laird NM. The family based association test method: strategies for studying general genotype--phenotype associations. Eur J Hum Genet. 2001 Apr; 9(4):301-6. PMID: 11313775.
    Citations: 297     Fields:    Translation:Humans
  137. Hudson JI, Laird NM, Betensky RA, Keck PE, Pope HG. Multivariate logistic regression for familial aggregation of two disorders. II. Analysis of studies of eating and mood disorders. Am J Epidemiol. 2001 Mar 01; 153(5):506-14. PMID: 11226983.
    Citations: 4     Fields:    Translation:Humans
  138. Horton NJ, Laird NM. Maximum likelihood analysis of logistic regression models with incomplete covariate data and auxiliary information. Biometrics. 2001 Mar; 57(1):34-42. PMID: 11252616.
    Citations: 6     Fields:    Translation:Humans
  139. Hudson JI, Laird NM, Betensky RA. Multivariate logistic regression for familial aggregation of two disorders. I. Development of models and methods. Am J Epidemiol. 2001 Mar 01; 153(5):500-5. PMID: 11226971.
    Citations: 8     Fields:    Translation:Humans
  140. Lake SL, Blacker D, Laird NM. Family-based tests of association in the presence of linkage. Am J Hum Genet. 2000 Dec; 67(6):1515-25. PMID: 11058432.
    Citations: 81     Fields:    Translation:HumansCells
  141. Rabinowitz D, Laird N. A unified approach to adjusting association tests for population admixture with arbitrary pedigree structure and arbitrary missing marker information. Hum Hered. 2000 Jul-Aug; 50(4):211-23. PMID: 10782012.
    Citations: 263     Fields:    Translation:Animals
  142. Hernández B, Gortmaker SL, Laird NM, Colditz GA, Parra-Cabrera S, Peterson KE. [Validity and reproducibility of a questionnaire on physical activity and non-activity for school children in Mexico City]. Salud Publica Mex. 2000 Jul-Aug; 42(4):315-23. PMID: 11026073.
    Citations: 19     Fields:    Translation:Humans
  143. Pauler DK, Laird NM. A mixture model for longitudinal data with application to assessment of noncompliance. Biometrics. 2000 Jun; 56(2):464-72. PMID: 10877305.
    Citations: 8     Fields:    Translation:Humans
  144. Fitzmaurice GM, Laird NM. Generalized linear mixture models for handling nonignorable dropouts in longitudinal studies. Biostatistics. 2000 Jun; 1(2):141-56. PMID: 12933516.
    Citations: 16     Fields:    
  145. Murphy JM, Laird NM, Monson RR, Sobol AM, Leighton AH. Incidence of depression in the Stirling County Study: historical and comparative perspectives. Psychol Med. 2000 May; 30(3):505-14. PMID: 10883707.
    Citations: 15     Fields:    Translation:Humans
  146. Murphy JM, Laird NM, Monson RR, Sobol AM, Leighton AH. A 40-year perspective on the prevalence of depression: the Stirling County Study. Arch Gen Psychiatry. 2000 Mar; 57(3):209-15. PMID: 10711905.
    Citations: 42     Fields:    Translation:Humans
  147. Horvath S, Laird NM, Knapp M. The transmission/disequilibrium test and parental-genotype reconstruction for X-chromosomal markers. Am J Hum Genet. 2000 Mar; 66(3):1161-7. PMID: 10712229.
    Citations: 16     Fields:    Translation:HumansCells
  148. Murphy JM, Monson RR, Laird NM, Sobol AM, Leighton AH. A comparison of diagnostic interviews for depression in the Stirling County study: challenges for psychiatric epidemiology. Arch Gen Psychiatry. 2000 Mar; 57(3):230-6. PMID: 10711909.
    Citations: 8     Fields:    Translation:Humans
  149. Lunetta KL, Faraone SV, Biederman J, Laird NM. Family-based tests of association and linkage that use unaffected sibs, covariates, and interactions. Am J Hum Genet. 2000 Feb; 66(2):605-14. PMID: 10677320.
    Citations: 46     Fields:    Translation:Humans
  150. Laird NM, Horvath S, Xu X. Implementing a unified approach to family-based tests of association. Genet Epidemiol. 2000; 19 Suppl 1:S36-42. PMID: 11055368.
    Citations: 351     Fields:    Translation:Humans
  151. Bates DW, Miller EB, Cullen DJ, Burdick L, Williams L, Laird N, Petersen LA, Small SD, Sweitzer BJ, Vander Vliet M, Leape LL. Patient risk factors for adverse drug events in hospitalized patients. ADE Prevention Study Group. Arch Intern Med. 1999 Nov 22; 159(21):2553-60. PMID: 10573045.
    Citations: 76     Fields:    Translation:Humans
  152. Korhonen PA, Laird NM, Palmgren J. Correcting for non-compliance in randomized trials: an application to the ATBC Study. Stat Med. 1999 Nov 15; 18(21):2879-97. PMID: 10523748.
    Citations: 5     Fields:    Translation:Humans
  153. Field AE, Byers T, Hunter DJ, Laird NM, Manson JE, Williamson DF, Willett WC, Colditz GA. Weight cycling, weight gain, and risk of hypertension in women. Am J Epidemiol. 1999 Sep 15; 150(6):573-9. PMID: 10489996.
    Citations: 29     Fields:    Translation:Humans
  154. Gortmaker SL, Cheung LW, Peterson KE, Chomitz G, Cradle JH, Dart H, Fox MK, Bullock RB, Sobol AM, Colditz G, Field AE, Laird N. Impact of a school-based interdisciplinary intervention on diet and physical activity among urban primary school children: eat well and keep moving. Arch Pediatr Adolesc Med. 1999 Sep; 153(9):975-83. PMID: 10482216.
    Citations: 54     Fields:    Translation:HumansCTClinical Trials
  155. Hernández B, Gortmaker SL, Colditz GA, Peterson KE, Laird NM, Parra-Cabrera S. Association of obesity with physical activity, television programs and other forms of video viewing among children in Mexico city. Int J Obes Relat Metab Disord. 1999 Aug; 23(8):845-54. PMID: 10490786.
    Citations: 44     Fields:    Translation:Humans
  156. Gortmaker SL, Peterson K, Wiecha J, Sobol AM, Dixit S, Fox MK, Laird N. Reducing obesity via a school-based interdisciplinary intervention among youth: Planet Health. Arch Pediatr Adolesc Med. 1999 Apr; 153(4):409-18. PMID: 10201726.
    Citations: 263     Fields:    Translation:HumansAnimalsCTClinical Trials
  157. Horton NJ, Laird NM. Maximum likelihood analysis of generalized linear models with missing covariates. Stat Methods Med Res. 1999 Mar; 8(1):37-50. PMID: 10347859.
    Citations: 11     Fields:    Translation:Humans
  158. Niu T, Yang J, Wang B, Chen W, Wang Z, Laird N, Wei E, Fang Z, Lindpaintner K, Rogus JJ, Xu X. Angiotensinogen gene polymorphisms M235T/T174M: no excess transmission to hypertensive Chinese. Hypertension. 1999 Feb; 33(2):698-702. PMID: 10024331.
    Citations: 4     Fields:    Translation:Humans
  159. Horvath S, Laird NM. A discordant-sibship test for disequilibrium and linkage: no need for parental data. Am J Hum Genet. 1998 Dec; 63(6):1886-97. PMID: 9837840.
    Citations: 38     Fields:    Translation:Humans
  160. Laird NM, Blacker D, Wilcox M. The sib transmission/disequilibrium test is a Mantel-Haenszel test. Am J Hum Genet. 1998 Dec; 63(6):1915-6. PMID: 9838272.
    Citations: 3     Fields:    Translation:Humans
  161. Bates DW, Leape LL, Cullen DJ, Laird N, Petersen LA, Teich JM, Burdick E, Hickey M, Kleefield S, Shea B, Vander Vliet M, Seger DL. Effect of computerized physician order entry and a team intervention on prevention of serious medication errors. JAMA. 1998 Oct 21; 280(15):1311-6. PMID: 9794308.
    Citations: 400     Fields:    Translation:Humans
  162. Blacker D, Wilcox MA, Laird NM, Rodes L, Horvath SM, Go RC, Perry R, Watson B, Bassett SS, McInnis MG, Albert MS, Hyman BT, Tanzi RE. Alpha-2 macroglobulin is genetically associated with Alzheimer disease. Nat Genet. 1998 Aug; 19(4):357-60. PMID: 9697696.
    Citations: 80     Fields:    Translation:HumansCells
  163. Hogan JW, Laird NM. Increasing efficiency from censored survival data by using random effects to model longitudinal covariates. Stat Methods Med Res. 1998 Mar; 7(1):28-48. PMID: 9533260.
    Citations: 5     Fields:    Translation:Humans
  164. Kleinman KP, Ibrahim JG, Laird NM. A Bayesian framework for intent-to-treat analysis with missing data. Biometrics. 1998 Mar; 54(1):265-78. PMID: 9544521.
    Citations: 3     Fields:    Translation:Humans
  165. Lipsitz SR, Dear KB, Laird NM, Molenberghs G. Tests for homogeneity of the risk difference when data are sparse. Biometrics. 1998 Mar; 54(1):148-60. PMID: 9544513.
    Citations:    Fields:    Translation:Humans
  166. Cnaan A, Laird NM, Slasor P. Using the general linear mixed model to analyse unbalanced repeated measures and longitudinal data. Stat Med. 1997 Oct 30; 16(20):2349-80. PMID: 9351170.
    Citations: 211     Fields:    Translation:Humans
  167. Fitzmaurice GM, Laird NM. Regression models for mixed discrete and continuous responses with potentially missing values. Biometrics. 1997 Mar; 53(1):110-22. PMID: 9147588.
    Citations: 16     Fields:    Translation:HumansPHPublic Health
  168. Van Eerdewegh P, Santangelo SL, Lee H, Laird NM, Blacker D. Probabilistic diagnosis in linkage analysis of bipolar disorder: putting weights on the fringe. Genet Epidemiol. 1997; 14(6):693-8. PMID: 9433565.
    Citations:    Fields:    Translation:HumansCells
  169. Bates DW, Spell N, Cullen DJ, Burdick E, Laird N, Petersen LA, Small SD, Sweitzer BJ, Leape LL. The costs of adverse drug events in hospitalized patients. Adverse Drug Events Prevention Study Group. JAMA. 1997 Jan 22-29; 277(4):307-11. PMID: 9002493.
    Citations: 315     Fields:    Translation:Humans
  170. Hogan JW, Laird NM. Mixture models for the joint distribution of repeated measures and event times. Stat Med. 1997 Jan 15-Feb 15; 16(1-3):239-57. PMID: 9004395.
    Citations: 53     Fields:    Translation:Humans
  171. Hogan JW, Laird NM. Model-based approaches to analysing incomplete longitudinal and failure time data. Stat Med. 1997 Jan 15-Feb 15; 16(1-3):259-72. PMID: 9004396.
    Citations: 33     Fields:    
  172. Hogan JW, Laird NM. Intention-to-treat analyses for incomplete repeated measures data. Biometrics. 1996 Sep; 52(3):1002-17. PMID: 8805765.
    Citations: 3     Fields:    Translation:Humans
  173. Fitzmaurice GM, Laird NM, Zahner GE, Daskalakis C. Bivariate logistic regression analysis of childhood psychopathology ratings using multiple informants. Am J Epidemiol. 1995 Dec 01; 142(11):1194-203. PMID: 7485066.
    Citations: 17     Fields:    Translation:Humans
  174. Bates DW, Cullen DJ, Laird N, Petersen LA, Small SD, Servi D, Laffel G, Sweitzer BJ, Shea BF, Hallisey R, et al. Incidence of adverse drug events and potential adverse drug events. Implications for prevention. ADE Prevention Study Group. JAMA. 1995 Jul 05; 274(1):29-34. PMID: 7791255.
    Citations: 543     Fields:    Translation:Humans
  175. Leape LL, Bates DW, Cullen DJ, Cooper J, Demonaco HJ, Gallivan T, Hallisey R, Ives J, Laird N, Laffel G, et al. Systems analysis of adverse drug events. ADE Prevention Study Group. JAMA. 1995 Jul 05; 274(1):35-43. PMID: 7791256.
    Citations: 311     Fields:    Translation:Humans
  176. Xu X, Laird N, Dockery DW, Schouten JP, Rijcken B, Weiss ST. Age, period, and cohort effects on pulmonary function in a 24-year longitudinal study. Am J Epidemiol. 1995 Mar 15; 141(6):554-66. PMID: 7900723.
    Citations: 16     Fields:    Translation:Humans
  177. Wang-Clow F, Lange M, Laird NM, Ware JH. A simulation study of estimators for rates of change in longitudinal studies with attrition. Stat Med. 1995 Feb 15; 14(3):283-97. PMID: 7724914.
    Citations: 1     Fields:    Translation:Humans
  178. Fitzmaurice GM, Laird NM, Lipsitz SR. Analysing incomplete longitudinal binary responses: a likelihood-based approach. Biometrics. 1994 Sep; 50(3):601-12. PMID: 7981387.
    Citations: 4     Fields:    Translation:Humans
  179. Stern RS, Laird N. The carcinogenic risk of treatments for severe psoriasis. Photochemotherapy Follow-up Study. Cancer. 1994 Jun 01; 73(11):2759-64. PMID: 8194017.
    Citations: 27     Fields:    Translation:Humans
  180. Lipsitz SR, Fitzmaurice GM, Orav EJ, Laird NM. Performance of generalized estimating equations in practical situations. Biometrics. 1994 Mar; 50(1):270-8. PMID: 8086610.
    Citations: 34     Fields:    Translation:Humans