Harvard Catalyst Profiles

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Francine Mary Benes, M.D., Ph.D.

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Research
research activities and funding
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
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  1. S10OD010737 (BENES, FRANCINE M.) Sep 3, 2012 - Sep 2, 2013
    NIH
    Confocal Imaging for Neuropsychiatric Research
    Role: Principal Investigator
  2. R01MH077175 (BENES, FRANCINE M.) Sep 6, 2007 - Aug 31, 2014
    NIH
    Gene Expression in Hippocampal Circuits of Bipolars and Schizophrenics
    Role: Principal Investigator
  3. R24MH068855 (BENES, FRANCINE M.) Sep 17, 2003 - Jul 31, 2013
    NIH
    A National Resource for Postmortem Brain Research
    Role: Principal Investigator
  4. R21MH062822 (BENES, FRANCINE M.) Sep 16, 2000 - Aug 31, 2003
    NIH
    HIPPOCAMPAL GENE EXPRESSION IN SCHIZOPHRENIA
    Role: Principal Investigator
  5. P50MH060450 (COYLE, JOSEPH T) Jul 21, 2000 - May 31, 2012
    NIH
    Glutamatergic Dysfunction and Schizophrenia
    Role: Co-Principal Investigator

Bibliographic
selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Nomoto M, Konopaske GT, Yamashita N, Aoki R, Jitsuki-Takahashi A, Nakamura H, Makihara H, Saito M, Saigusa Y, Nakamura F, Watanabe K, Baba T, Benes FM, Tobe BTD, Pernia CD, Coyle JT, Sidman RL, Hirayasu Y, Snyder EY, Goshima Y. Clinical evidence that a dysregulated master neural network modulator may aid in diagnosing schizophrenia. Proc Natl Acad Sci U S A. 2021 08 03; 118(31). PMID: 34330827.
    Citations: 1     Fields:    Translation:Humans
  2. Konopaske GT, Balu DT, Presti KT, Chan G, Benes FM, Coyle JT. Dysbindin-1 contributes to prefrontal cortical dendritic arbor pathology in schizophrenia. Schizophr Res. 2018 11; 201:270-277. PMID: 29759351; PMCID: PMC6230503.
    Citations: 9     Fields:    Translation:HumansAnimalsCells
  3. Ruzicka WB, Subburaju S, Coyle JT, Benes FM. Location matters: distinct DNA methylation patterns in GABAergic interneuronal populations from separate microcircuits within the human hippocampus. Hum Mol Genet. 2018 01 15; 27(2):254-265. PMID: 29106556; PMCID: PMC5886141.
    Citations: 4     Fields:    Translation:HumansCells
  4. Subburaju S, Coleman AJ, Cunningham MG, Ruzicka WB, Benes FM. Epigenetic Regulation of Glutamic Acid Decarboxylase 67 in a Hippocampal Circuit. Cereb Cortex. 2017 11 01; 27(11):5284-5293. PMID: 27733539; PMCID: PMC6411031.
    Citations: 5     Fields:    Translation:AnimalsCells
  5. Benes FM. Increases of Calbindin-Containing Chandelier Cartridges in Schizophrenia: Fact or Artifact? Biol Psychiatry. 2017 07 01; 82(1):4-5. PMID: 28619251.
    Citations:    Fields:    Translation:Humans
  6. Ruzicka WB, Subburaju S, Benes FM. Variability of DNA Methylation within Schizophrenia Risk Loci across Subregions of Human Hippocampus. Genes (Basel). 2017 May 15; 8(5). PMID: 28505127.
    Citations: 3     Fields:    
  7. Sonntag KC, Tejada G, Subburaju S, Berretta S, Benes FM, Woo TU. Limited predictability of postmortem human brain tissue quality by RNA integrity numbers. J Neurochem. 2016 07; 138(1):53-9. PMID: 27062510; PMCID: PMC4915987.
    Citations: 19     Fields:    Translation:HumansCells
  8. Subburaju S, Coleman AJ, Ruzicka WB, Benes FM. Toward dissecting the etiology of schizophrenia: HDAC1 and DAXX regulate GAD67 expression in an in vitro hippocampal GABA neuron model. Transl Psychiatry. 2016 Jan 26; 6:e723. PMID: 26812044; PMCID: PMC5068889.
    Citations: 11     Fields:    Translation:HumansAnimalsCells
  9. Benes FM. The GABA system in schizophrenia: cells, molecules and microcircuitry. Schizophr Res. 2015 Sep; 167(1-3):1-3. PMID: 26255083.
    Citations: 21     Fields:    Translation:Humans
  10. Ruzicka WB, Subburaju S, Benes FM. Circuit- and Diagnosis-Specific DNA Methylation Changes at ?-Aminobutyric Acid-Related Genes in Postmortem Human Hippocampus in Schizophrenia and Bipolar Disorder. JAMA Psychiatry. 2015 Jun; 72(6):541-51. PMID: 25738424; PMCID: PMC5547581.
    Citations: 48     Fields:    Translation:HumansCells
  11. Konopaske GT, Subburaju S, Coyle JT, Benes FM. Altered prefrontal cortical MARCKS and PPP1R9A mRNA expression in schizophrenia and bipolar disorder. Schizophr Res. 2015 May; 164(1-3):100-8. PMID: 25757715; PMCID: PMC4409526.
    Citations: 12     Fields:    Translation:HumansAnimalsCells
  12. Benes FM. Building models for postmortem abnormalities in hippocampus of schizophrenics. Schizophr Res. 2015 Sep; 167(1-3):73-83. PMID: 25749020.
    Citations: 11     Fields:    Translation:HumansAnimalsCells
  13. Konopaske GT, Lange N, Coyle JT, Benes FM. Prefrontal cortical dendritic spine pathology in schizophrenia and bipolar disorder. JAMA Psychiatry. 2014 Dec 01; 71(12):1323-31. PMID: 25271938; PMCID: PMC5510541.
    Citations: 163     Fields:    Translation:HumansAnimalsCells
  14. Berretta S, Heckers S, Benes FM. Searching human brain for mechanisms of psychiatric disorders. Implications for studies on schizophrenia. Schizophr Res. 2015 Sep; 167(1-3):91-7. PMID: 25458567; PMCID: PMC4427537.
    Citations: 5     Fields:    Translation:Humans
  15. Baird PM, Benes FM, Chan CH, Eng CB, Groover KH, Prodanovic Z, Rawley-Payne M, Kizza R, Hia C, Abouhamze A. How is your biobank handling disaster recovery efforts? Biopreserv Biobank. 2013 Aug; 11(4):194-201. PMID: 24845584.
    Citations: 2     Fields:    Translation:Humans
  16. Ohtsuka N, Badurek S, Busslinger M, Benes FM, Minichiello L, Rudolph U. GABAergic neurons regulate lateral ventricular development via transcription factor Pax5. Genesis. 2013 Apr; 51(4):234-45. PMID: 23349049.
    Citations: 8     Fields:    Translation:AnimalsCells
  17. Benes FM. A new paradigm for understanding gamma-aminobutyric acid cell pathology in schizophrenia? Biol Psychiatry. 2012 Nov 01; 72(9):712-3. PMID: 23036505.
    Citations: 2     Fields:    Translation:HumansCells
  18. Sheng G, Demers M, Subburaju S, Benes FM. Differences in the circuitry-based association of copy numbers and gene expression between the hippocampi of patients with schizophrenia and the hippocampi of patients with bipolar disorder. Arch Gen Psychiatry. 2012 Jun; 69(6):550-61. PMID: 22309971.
    Citations: 10     Fields:    Translation:Humans
  19. Subburaju S, Benes FM. Induction of the GABA cell phenotype: an in vitro model for studying neurodevelopmental disorders. PLoS One. 2012; 7(3):e33352. PMID: 22457755.
    Citations: 16     Fields:    Translation:AnimalsCells
  20. Gisabella B, Bolshakov VY, Benes FM. Kainate receptor-mediated modulation of hippocampal fast spiking interneurons in a rat model of schizophrenia. PLoS One. 2012; 7(3):e32483. PMID: 22396770.
    Citations: 4     Fields:    Translation:AnimalsCells
  21. Benes FM. Nicotinic receptors and functional regulation of GABA cell microcircuitry in bipolar disorder and schizophrenia. Handb Exp Pharmacol. 2012; (213):401-17. PMID: 23027422.
    Citations: 7     Fields:    Translation:HumansCells
  22. Benes FM. The neurobiology of bipolar disorder: from circuits to cells to molecular regulation. Curr Top Behav Neurosci. 2011; 5:127-38. PMID: 25236553.
    Citations: 1     Fields:    Translation:Humans
  23. Benes FM. Regulation of cell cycle and DNA repair in post-mitotic GABA neurons in psychotic disorders. Neuropharmacology. 2011 Jun; 60(7-8):1232-42. PMID: 21184762.
    Citations: 15     Fields:    Translation:HumansCells
  24. Deep-Soboslay A, Benes FM, Haroutunian V, Ellis JK, Kleinman JE, Hyde TM. Psychiatric brain banking: three perspectives on current trends and future directions. Biol Psychiatry. 2011 Jan 15; 69(2):104-12. PMID: 20673875.
    Citations: 29     Fields:    Translation:Humans
  25. Benes FM. Relationship of GAD(67) regulation to cell cycle and DNA repair in GABA neurons in the adult hippocampus: bipolar disorder versus schizophrenia. Cell Cycle. 2010 Feb 15; 9(4):625-7. PMID: 20107308.
    Citations: 8     Fields:    Translation:HumansCells
  26. Benes FM. Amygdalocortical circuitry in schizophrenia: from circuits to molecules. Neuropsychopharmacology. 2010 Jan; 35(1):239-57. PMID: 19727065.
    Citations: 86     Fields:    Translation:HumansAnimalsCells
  27. Benes FM, Lim B, Subburaju S. Site-specific regulation of cell cycle and DNA repair in post-mitotic GABA cells in schizophrenic versus bipolars. Proc Natl Acad Sci U S A. 2009 Jul 14; 106(28):11731-6. PMID: 19564623.
    Citations: 29     Fields:    Translation:HumansCells
  28. Berretta S, Gisabella B, Benes FM. A rodent model of schizophrenia derived from postmortem studies. Behav Brain Res. 2009 Dec 07; 204(2):363-8. PMID: 19539659.
    Citations: 4     Fields:    Translation:AnimalsCells
  29. Benes FM. Neural circuitry models of schizophrenia: is it dopamine, GABA, glutamate, or something else? Biol Psychiatry. 2009 Jun 15; 65(12):1003-5. PMID: 19481640.
    Citations: 15     Fields:    Translation:HumansCells
  30. Nasrallah HA, Keshavan MS, Benes FM, Braff DL, Green AI, Gur RE, Kane JM, Perkins DO, Weiden PJ, Weinberger DR, Correll CU. Proceedings and data from The Schizophrenia Summit: a critical appraisal to improve the management of Schizophrenia. J Clin Psychiatry. 2009; 70 Suppl 1:4-46. PMID: 19292973.
    Citations: 7     Fields:    Translation:Humans
  31. Benes FM, Lim B, Matzilevich D, Subburaju S, Walsh JP. Circuitry-based gene expression profiles in GABA cells of the trisynaptic pathway in schizophrenics versus bipolars. Proc Natl Acad Sci U S A. 2008 Dec 30; 105(52):20935-40. PMID: 19104056.
    Citations: 34     Fields:    Translation:HumansCells
  32. Simunovic F, Yi M, Wang Y, Macey L, Brown LT, Krichevsky AM, Andersen SL, Stephens RM, Benes FM, Sonntag KC. Gene expression profiling of substantia nigra dopamine neurons: further insights into Parkinson's disease pathology. Brain. 2009 Jul; 132(Pt 7):1795-809. PMID: 19052140; PMCID: PMC2724914.
    Citations: 156     Fields:    Translation:HumansCells
  33. Gisabella B, Cunningham MG, Bolshakov VY, Benes FM. Amygdala-dependent regulation of electrical properties of hippocampal interneurons in a model of schizophrenia. Biol Psychiatry. 2009 Mar 15; 65(6):464-72. PMID: 19027103.
    Citations: 11     Fields:    Translation:AnimalsCells
  34. Woo TU, Shrestha K, Lamb D, Minns MM, Benes FM. N-methyl-D-aspartate receptor and calbindin-containing neurons in the anterior cingulate cortex in schizophrenia and bipolar disorder. Biol Psychiatry. 2008 Nov 01; 64(9):803-9. PMID: 18585682.
    Citations: 20     Fields:    Translation:HumansCells
  35. Lisman JE, Coyle JT, Green RW, Javitt DC, Benes FM, Heckers S, Grace AA. Circuit-based framework for understanding neurotransmitter and risk gene interactions in schizophrenia. Trends Neurosci. 2008 May; 31(5):234-42. PMID: 18395805.
    Citations: 468     Fields:    Translation:HumansAnimals
  36. Cunningham MG, Bhattacharyya S, Benes FM. Increasing Interaction of amygdalar afferents with GABAergic interneurons between birth and adulthood. Cereb Cortex. 2008 Jul; 18(7):1529-35. PMID: 17971342.
    Citations: 44     Fields:    Translation:AnimalsCells
  37. Cunningham MG, Ames HM, Donalds RA, Benes FM. Construction and implantation of a microinfusion system for sustained delivery of neuroactive agents. J Neurosci Methods. 2008 Jan 30; 167(2):213-20. PMID: 17923158.
    Citations: 1     Fields:    Translation:Animals
  38. Woo TU, Shrestha K, Amstrong C, Minns MM, Walsh JP, Benes FM. Differential alterations of kainate receptor subunits in inhibitory interneurons in the anterior cingulate cortex in schizophrenia and bipolar disorder. Schizophr Res. 2007 Nov; 96(1-3):46-61. PMID: 17698324; PMCID: PMC2712609.
    Citations: 27     Fields:    Translation:Humans
  39. Benes FM. Searching for unique endophenotypes for schizophrenia and bipolar disorder within neural circuits and their molecular regulatory mechanisms. Schizophr Bull. 2007 Jul; 33(4):932-6. PMID: 17575303.
    Citations: 21     Fields:    Translation:HumansCells
  40. Benes FM, Lim B, Matzilevich D, Walsh JP, Subburaju S, Minns M. Regulation of the GABA cell phenotype in hippocampus of schizophrenics and bipolars. Proc Natl Acad Sci U S A. 2007 Jun 12; 104(24):10164-9. PMID: 17553960; PMCID: PMC1888575.
    Citations: 229     Fields:    Translation:HumansCells
  41. Buttner N, Bhattacharyya S, Walsh J, Benes FM. DNA fragmentation is increased in non-GABAergic neurons in bipolar disorder but not in schizophrenia. Schizophr Res. 2007 Jul; 93(1-3):33-41. PMID: 17442540; PMCID: PMC1991302.
    Citations: 14     Fields:    Translation:HumansCells
  42. Benes FM, Matzilevich D, Burke RE, Walsh J. The expression of proapoptosis genes is increased in bipolar disorder, but not in schizophrenia. Mol Psychiatry. 2006 Mar; 11(3):241-51. PMID: 16288314.
    Citations: 63     Fields:    Translation:HumansCells
  43. Burke RE, Walsh J, Matzilevich D, Benes FM. Mapping of hippocampal gene clusters regulated by the amygdala to nonlinkage sites for schizophrenia. Mol Psychiatry. 2006 Feb; 11(2):158-71. PMID: 16302010.
    Citations: 1     Fields:    Translation:HumansAnimalsCells
  44. Benes FM, Gisabella B. Rat modeling for GABA defects in schizophrenia. Adv Pharmacol. 2006; 54:73-93. PMID: 17175811.
    Citations:    Fields:    Translation:HumansAnimalsCells
  45. Berretta S, Benes FM. A rat model for neural circuitry abnormalities in schizophrenia. Nat Protoc. 2006; 1(2):833-9. PMID: 17406315.
    Citations: 5     Fields:    Translation:AnimalsCells
  46. Benes FM. Strategies for improving sensitivity of gene expression profiling: regulation of apoptosis in the limbic lobe of schizophrenics and bipolars. Prog Brain Res. 2006; 158:153-72. PMID: 17027696.
    Citations: 4     Fields:    Translation:HumansAnimals
  47. Gisabella B, Bolshakov VY, Benes FM. Regulation of synaptic plasticity in a schizophrenia model. Proc Natl Acad Sci U S A. 2005 Sep 13; 102(37):13301-6. PMID: 16131546; PMCID: PMC1201605.
    Citations: 14     Fields:    Translation:Animals
  48. Cunningham MG, Connor CM, Zhang K, Benes FM. Diminished serotonergic innervation of adult medial prefrontal cortex after 6-OHDA lesions in the newborn rat. Brain Res Dev Brain Res. 2005 Jun 30; 157(2):124-31. PMID: 15885807.
    Citations: 10     Fields:    Translation:AnimalsCells
  49. Benes FM. Ethical issues in brain banking. Curr Opin Psychiatry. 2005 May; 18(3):277-83. PMID: 16639152.
    Citations: 3     Fields:    
  50. Heckers S, Benes F. Hippocampus, III: GABA-containing cell bodies and GAD mRNA. Am J Psychiatry. 2005 Mar; 162(3):450. PMID: 15741459.
    Citations: 2     Fields:    Translation:HumansCells
  51. Todtenkopf MS, Vincent SL, Benes FM. A cross-study meta-analysis and three-dimensional comparison of cell counting in the anterior cingulate cortex of schizophrenic and bipolar brain. Schizophr Res. 2005 Feb 01; 73(1):79-89. PMID: 15567080.
    Citations: 47     Fields:    Translation:HumansCells
  52. Pantazopoulos H, Stone D, Walsh J, Benes FM. Differences in the cellular distribution of D1 receptor mRNA in the hippocampus of bipolars and schizophrenics. Synapse. 2004 Dec 01; 54(3):147-55. PMID: 15452863.
    Citations: 13     Fields:    Translation:HumansCells
  53. Benes FM, Burke RE, Walsh J, Berretta S, Matzilevich D, Minns M, Konradi C. Acute amygdalar activation induces an upregulation of multiple monoamine G protein coupled pathways in rat hippocampus. Mol Psychiatry. 2004 Oct; 9(10):932-45, 895. PMID: 15170462.
    Citations: 8     Fields:    Translation:AnimalsCells
  54. Benes FM. Konrad Lorenz, 1903-1989. Am J Psychiatry. 2004 Oct; 161(10):1767. PMID: 15465969.
    Citations: 1     Fields:    Translation:Animals
  55. Woo TU, Walsh JP, Benes FM. Density of glutamic acid decarboxylase 67 messenger RNA-containing neurons that express the N-methyl-D-aspartate receptor subunit NR2A in the anterior cingulate cortex in schizophrenia and bipolar disorder. Arch Gen Psychiatry. 2004 Jul; 61(7):649-57. PMID: 15237077.
    Citations: 156     Fields:    Translation:HumansCells
  56. Konradi C, Eaton M, MacDonald ML, Walsh J, Benes FM, Heckers S. Molecular evidence for mitochondrial dysfunction in bipolar disorder. Arch Gen Psychiatry. 2004 Mar; 61(3):300-8. PMID: 14993118.
    Citations: 170     Fields:    Translation:HumansCells
  57. Benes FM. A disturbance of late myelination as a trigger for Alzheimer's disease. Neurobiol Aging. 2004 Jan; 25(1):41-3. PMID: 14675729.
    Citations: 8     Fields:    Translation:HumansCells
  58. Berretta S, Lange N, Bhattacharyya S, Sebro R, Garces J, Benes FM. Long-term effects of amygdala GABA receptor blockade on specific subpopulations of hippocampal interneurons. Hippocampus. 2004; 14(7):876-94. PMID: 15382257.
    Citations: 29     Fields:    Translation:AnimalsCells
  59. Benes FM. Schizophrenia, II: amygdalar fiber alteration as etiology? Am J Psychiatry. 2003 Jun; 160(6):1053. PMID: 12777259.
    Citations: 1     Fields:    Translation:HumansAnimals
  60. Benes FM, Walsh J, Bhattacharyya S, Sheth A, Berretta S. DNA fragmentation decreased in schizophrenia but not bipolar disorder. Arch Gen Psychiatry. 2003 Apr; 60(4):359-64. PMID: 12695312.
    Citations: 22     Fields:    Translation:Humans
  61. Benes FM. Deserving the last great gift. Cerebrum. 2003; 5(3):61-73. PMID: 16184678.
    Citations:    Translation:Humans
  62. Cunningham MG, Bhattacharyya S, Benes FM. Amygdalo-cortical sprouting continues into early adulthood: implications for the development of normal and abnormal function during adolescence. J Comp Neurol. 2002 Nov 11; 453(2):116-30. PMID: 12373778.
    Citations: 204     Fields:    Translation:AnimalsCells
  63. Heckers S, Stone D, Walsh J, Shick J, Koul P, Benes FM. Differential hippocampal expression of glutamic acid decarboxylase 65 and 67 messenger RNA in bipolar disorder and schizophrenia. Arch Gen Psychiatry. 2002 Jun; 59(6):521-9. PMID: 12044194.
    Citations: 99     Fields:    Translation:HumansCells
  64. Veale D, Poussin G, Benes F, Pepin JL, Levy P. Identification of quality of life concerns of patients with obstructive sleep apnoea at the time of initiation of continuous positive airway pressure: a discourse analysis. Qual Life Res. 2002 Jun; 11(4):389-99. PMID: 12086124.
    Citations: 9     Fields:    Translation:Humans
  65. Tsvetkov E, Carlezon WA, Benes FM, Kandel ER, Bolshakov VY. Fear conditioning occludes LTP-induced presynaptic enhancement of synaptic transmission in the cortical pathway to the lateral amygdala. Neuron. 2002 Apr 11; 34(2):289-300. PMID: 11970870.
    Citations: 147     Fields:    Translation:AnimalsCells
  66. Benes FM, Vincent SL, Todtenkopf M. The density of pyramidal and nonpyramidal neurons in anterior cingulate cortex of schizophrenic and bipolar subjects. Biol Psychiatry. 2001 Sep 15; 50(6):395-406. PMID: 11566156.
    Citations: 88     Fields:    Translation:HumansCells
  67. Benes FM, Berretta S. GABAergic interneurons: implications for understanding schizophrenia and bipolar disorder. Neuropsychopharmacology. 2001 Jul; 25(1):1-27. PMID: 11377916.
    Citations: 413     Fields:    Translation:HumansAnimalsCells
  68. Berretta S, Munno DW, Benes FM. Amygdalar activation alters the hippocampal GABA system: "partial" modelling for postmortem changes in schizophrenia. J Comp Neurol. 2001 Mar 05; 431(2):129-38. PMID: 11169995.
    Citations: 25     Fields:    Translation:AnimalsCells
  69. Stone DJ, Walsh JP, Sebro R, Stevens R, Pantazopolous H, Benes FM. Effects of pre- and postnatal corticosterone exposure on the rat hippocampal GABA system. Hippocampus. 2001; 11(5):492-507. PMID: 11732703.
    Citations: 13     Fields:    Translation:Animals
  70. Benes FM, Todtenkopf MS, Kostoulakos P. GluR5,6,7 subunit immunoreactivity on apical pyramidal cell dendrites in hippocampus of schizophrenics and manic depressives. Hippocampus. 2001; 11(5):482-91. PMID: 11732702.
    Citations: 14     Fields:    Translation:HumansCells
  71. Benes FM. Carlsson and the discovery of dopamine. Trends Pharmacol Sci. 2001 Jan; 22(1):46-7. PMID: 11165672.
    Citations: 6     Fields:    Translation:HumansAnimals
  72. Benes FM, Lange N. Two-dimensional versus three-dimensional cell counting: a practical perspective. Trends Neurosci. 2001 Jan; 24(1):11-7. PMID: 11163882.
    Citations: 56     Fields:    Translation:HumansAnimalsCells
  73. Benes FM, Todtenkopf MS, Logiotatos P, Williams M. Glutamate decarboxylase(65)-immunoreactive terminals in cingulate and prefrontal cortices of schizophrenic and bipolar brain. J Chem Neuroanat. 2000 Dec; 20(3-4):259-69. PMID: 11207424.
    Citations: 31     Fields:    Translation:HumansCells
  74. Benes FM, Taylor JB, Cunningham MC. Convergence and plasticity of monoaminergic systems in the medial prefrontal cortex during the postnatal period: implications for the development of psychopathology. Cereb Cortex. 2000 Oct; 10(10):1014-27. PMID: 11007552.
    Citations: 93     Fields:    Translation:HumansAnimals
  75. Benes FM, Berretta S. Amygdalo-entorhinal inputs to the hippocampal formation in relation to schizophrenia. Ann N Y Acad Sci. 2000 Jun; 911:293-304. PMID: 10911881.
    Citations: 21     Fields:    Translation:HumansAnimals
  76. Benes FM. Emerging principles of altered neural circuitry in schizophrenia. Brain Res Brain Res Rev. 2000 Mar; 31(2-3):251-69. PMID: 10719152.
    Citations: 119     Fields:    Translation:HumansAnimals
  77. Davidoff SA, Chu HM, Benes FM. Acute administration of SCH23390 increases D(1) receptors on nonpyramidal neurons in rat mPFC. Synapse. 2000 Mar 01; 35(3):173-81. PMID: 10657024.
    Citations:    Fields:    Translation:AnimalsCells
  78. Benes FM, Todtenkopf MS. Effect of age and neuroleptics on tyrosine hydroxylase-IR in sector CA2 of schizophrenic brain. Neuroreport. 1999 Nov 26; 10(17):3527-30. PMID: 10619638.
    Citations: 5     Fields:    Translation:HumansCells
  79. Benes FM. Alterations of neural circuitry within layer II of anterior cingulate cortex in schizophrenia. J Psychiatr Res. 1999 Nov-Dec; 33(6):511-2. PMID: 10628527.
    Citations: 1     Fields:    Translation:Humans
  80. Benes FM. Evidence for altered trisynaptic circuitry in schizophrenic hippocampus. Biol Psychiatry. 1999 Sep 01; 46(5):589-99. PMID: 10472413.
    Citations: 58     Fields:    Translation:HumansCells
  81. Stone DJ, Walsh J, Benes FM. Localization of cells preferentially expressing GAD(67) with negligible GAD(65) transcripts in the rat hippocampus. A double in situ hybridization study. Brain Res Mol Brain Res. 1999 Aug 25; 71(2):201-9. PMID: 10521574.
    Citations: 13     Fields:    Translation:AnimalsCells
  82. Benes FM. Brain development, VII. Human brain growth spans decades. Am J Psychiatry. 1998 Nov; 155(11):1489. PMID: 9812107.
    Citations: 13     Fields:    Translation:HumansCells
  83. Todtenkopf MS, Benes FM. Distribution of glutamate decarboxylase65 immunoreactive puncta on pyramidal and nonpyramidal neurons in hippocampus of schizophrenic brain. Synapse. 1998 Aug; 29(4):323-32. PMID: 9661250.
    Citations: 23     Fields:    Translation:HumansCells
  84. Benes FM, Kwok EW, Vincent SL, Todtenkopf MS. A reduction of nonpyramidal cells in sector CA2 of schizophrenics and manic depressives. Biol Psychiatry. 1998 Jul 15; 44(2):88-97. PMID: 9646890.
    Citations: 139     Fields:    Translation:HumansCells
  85. Bolte Taylor J, Cunningham MC, Benes FM. Neonatal raphe lesions increase dopamine fibers in prefrontal cortex of adult rats. Neuroreport. 1998 Jun 01; 9(8):1811-5. PMID: 9665606.
    Citations: 7     Fields:    Translation:AnimalsCells
  86. Benes F, Coyle JT. Déja vu all over again. Biol Psychiatry. 1998 Jun 01; 43(11):781-2. PMID: 9611666.
    Citations:    Fields:    Translation:Humans
  87. Bursztajn S, Vincent S, Brodsky FM, Benes F, Morris SA. A novel AP180-related protein in vesicles that concentrate at acetylcholine receptor clusters. J Cell Biochem. 1998 Mar 15; 68(4):457-71. PMID: 9493909.
    Citations:    Fields:    Translation:AnimalsCells
  88. Benes FM. Model generation and testing to probe neural circuitry in the cingulate cortex of postmortem schizophrenic brain. Schizophr Bull. 1998; 24(2):219-30. PMID: 9613622.
    Citations: 21     Fields:    Translation:HumansCells
  89. Davidoff SA, Benes FM. High-resolution scatchard analysis shows D1 receptor binding on pyramidal and nonpyramidal neurons. Synapse. 1998 Jan; 28(1):83-90. PMID: 9414021.
    Citations: 8     Fields:    Translation:AnimalsCells
  90. Baldessarini RJ, Hegarty JD, Bird ED, Benes FM. Meta-analysis of postmortem studies of Alzheimer's disease-like neuropathology in schizophrenia. Am J Psychiatry. 1997 Jun; 154(6):861-3. PMID: 9167518.
    Citations: 10     Fields:    Translation:HumansCells
  91. Benes FM, Wickramasinghe R, Vincent SL, Khan Y, Todtenkopf M. Uncoupling of GABA(A) and benzodiazepine receptor binding activity in the hippocampal formation of schizophrenic brain. Brain Res. 1997 Apr 25; 755(1):121-9. PMID: 9163547.
    Citations: 18     Fields:    Translation:HumansCells
  92. Barondes SH, Alberts BM, Andreasen NC, Bargmann C, Benes F, Goldman-Rakic P, Gottesman I, Heinemann SF, Jones EG, Kirschner M, Lewis D, Raff M, Roses A, Rubenstein J, Snyder S, Watson SJ, Weinberger DR, Yolken RH. Workshop on schizophrenia. Proc Natl Acad Sci U S A. 1997 Mar 04; 94(5):1612-4. PMID: 9050825; PMCID: PMC34140.
    Citations: 7     Fields:    Translation:Humans
  93. Benes FM. The role of stress and dopamine-GABA interactions in the vulnerability for schizophrenia. J Psychiatr Res. 1997 Mar-Apr; 31(2):257-75. PMID: 9278189.
    Citations: 15     Fields:    Translation:Humans
  94. Benes FM, Todtenkopf MS, Taylor JB. Differential distribution of tyrosine hydroxylase fibers on small and large neurons in layer II of anterior cingulate cortex of schizophrenic brain. Synapse. 1997 Jan; 25(1):80-92. PMID: 8987151.
    Citations: 11     Fields:    Translation:HumansCells
  95. Benes FM. What an archaeological dig can tell us about macro- and microcircuitry in brains of schizophrenia subjects. Schizophr Bull. 1997; 23(3):503-7. PMID: 9327512.
    Citations: 2     Fields:    Translation:HumansCells
  96. Benes FM, Vincent SL, Marie A, Khan Y. Up-regulation of GABAA receptor binding on neurons of the prefrontal cortex in schizophrenic subjects. Neuroscience. 1996 Dec; 75(4):1021-31. PMID: 8938738.
    Citations: 78     Fields:    Translation:HumansCells
  97. Benes FM, Vincent SL, Molloy R, Khan Y. Increased interaction of dopamine-immunoreactive varicosities with GABA neurons of rat medial prefrontal cortex occurs during the postweanling period. Synapse. 1996 Aug; 23(4):237-45. PMID: 8855508.
    Citations: 33     Fields:    Translation:AnimalsCells
  98. Benes FM, Khan Y, Vincent SL, Wickramasinghe R. Differences in the subregional and cellular distribution of GABAA receptor binding in the hippocampal formation of schizophrenic brain. Synapse. 1996 Apr; 22(4):338-49. PMID: 8867028.
    Citations: 36     Fields:    Translation:HumansCells
  99. Longson D, Deakin JF, Benes FM. Increased density of entorhinal glutamate-immunoreactive vertical fibers in schizophrenia. J Neural Transm (Vienna). 1996; 103(4):503-7. PMID: 9617791.
    Citations: 11     Fields:    Translation:HumansCells
  100. Benes FM. Development of the glutamate, GABA, and dopamine systems in relation to NRH-induced neurotoxicity. Biol Psychiatry. 1995 Dec 15; 38(12):783-7. PMID: 8750035.
    Citations: 1     Fields:    Translation:Animals
  101. Benes FM. Altered glutamatergic and GABAergic mechanisms in the cingulate cortex of the schizophrenic brain. Arch Gen Psychiatry. 1995 Dec; 52(12):1015-8; discussion 1019-24. PMID: 7492253.
    Citations: 11     Fields:    Translation:HumansCells
  102. Vincent SL, Pabreza L, Benes FM. Postnatal maturation of GABA-immunoreactive neurons of rat medial prefrontal cortex. J Comp Neurol. 1995 Apr 24; 355(1):81-92. PMID: 7636016.
    Citations: 15     Fields:    Translation:AnimalsCells
  103. Vincent SL, Khan Y, Benes FM. Cellular colocalization of dopamine D1 and D2 receptors in rat medial prefrontal cortex. Synapse. 1995 Feb; 19(2):112-20. PMID: 7725240.
    Citations: 37     Fields:    Translation:Animals
  104. Benes FM, Tamminga CA. Images in neuroscience. Cortical GABA-ergic interneurons. Am J Psychiatry. 1994 Aug; 151(8):1104. PMID: 8037242.
    Citations: 2     Fields:    Translation:HumansCells
  105. Benes FM, Turtle M, Khan Y, Farol P. Myelination of a key relay zone in the hippocampal formation occurs in the human brain during childhood, adolescence, and adulthood. Arch Gen Psychiatry. 1994 Jun; 51(6):477-84. PMID: 8192550.
    Citations: 230     Fields:    Translation:HumansAnimalsCells
  106. Vincent SL, Adamec E, Sorensen I, Benes FM. The effects of chronic haloperidol administration on GABA-immunoreactive axon terminals in rat medial prefrontal cortex. Synapse. 1994 May; 17(1):26-35. PMID: 8042144.
    Citations: 9     Fields:    Translation:AnimalsCells
  107. Benes FM, Vincent SL, Molloy R. Dopamine-immunoreactive axon varicosities form nonrandom contacts with GABA-immunoreactive neurons of rat medial prefrontal cortex. Synapse. 1993 Dec; 15(4):285-95. PMID: 8153876.
    Citations: 21     Fields:    Translation:AnimalsCells
  108. Benes FM. The relationship between structural brain imaging and histopathologic findings in schizophrenia research. Harv Rev Psychiatry. 1993 Jul-Aug; 1(2):100-9. PMID: 9384836.
    Citations: 7     Fields:    Translation:HumansCells
  109. Vincent SL, Khan Y, Benes FM. Cellular distribution of dopamine D1 and D2 receptors in rat medial prefrontal cortex. J Neurosci. 1993 Jun; 13(6):2551-64. PMID: 8501521; PMCID: PMC6576493.
    Citations: 66     Fields:    Translation:AnimalsCells
  110. Benes FM. Neurobiological investigations in cingulate cortex of schizophrenic brain. Schizophr Bull. 1993; 19(3):537-49. PMID: 8235456.
    Citations: 29     Fields:    Translation:HumansCells
  111. Benes FM, Sorensen I, Vincent SL, Bird ED, Sathi M. Increased density of glutamate-immunoreactive vertical processes in superficial laminae in cingulate cortex of schizophrenic brain. Cereb Cortex. 1992 Nov-Dec; 2(6):503-12. PMID: 1282404.
    Citations: 26     Fields:    Translation:Humans
  112. Benes FM, Vincent SL, Alsterberg G, Bird ED, SanGiovanni JP. Increased GABAA receptor binding in superficial layers of cingulate cortex in schizophrenics. J Neurosci. 1992 Mar; 12(3):924-9. PMID: 1372045; PMCID: PMC6576044.
    Citations: 71     Fields:    Translation:Humans
  113. Vincent SL, Sorensen I, Benes FM. Localization and high-resolution imaging of cortical neurotransmitter compartments using confocal laser scanning microscopy: GABA and glutamate interactions in rat cortex. Biotechniques. 1991 Nov; 11(5):628-34. PMID: 1687109.
    Citations: 1     Fields:    Translation:Animals
  114. Benes FM, Vincent SL. Changes in dendritic spine morphology in response to increased availability of monoamines in rat medial prefrontal cortex. Synapse. 1991 Nov; 9(3):235-7. PMID: 1776134.
    Citations: 3     Fields:    Translation:AnimalsCells
  115. Benes FM, McSparren J, Bird ED, SanGiovanni JP, Vincent SL. Deficits in small interneurons in prefrontal and cingulate cortices of schizophrenic and schizoaffective patients. Arch Gen Psychiatry. 1991 Nov; 48(11):996-1001. PMID: 1747023.
    Citations: 186     Fields:    Translation:HumansCells
  116. Vincent SL, McSparren J, Wang RY, Benes FM. Evidence for ultrastructural changes in cortical axodendritic synapses following long-term treatment with haloperidol or clozapine. Neuropsychopharmacology. 1991 Nov; 5(3):147-55. PMID: 1755930.
    Citations: 7     Fields:    Translation:AnimalsCells
  117. Benes FM. Evidence for neurodevelopment disturbances in anterior cingulate cortex of post-mortem schizophrenic brain. Schizophr Res. 1991 Oct; 5(3):187-8. PMID: 1760386.
    Citations: 6     Fields:    Translation:HumansCells
  118. Benes FM, Farol PA, Majocha RE, Marotta CA, Bird ED. Evidence for axonal loss in regions occupied by senile plaques in Alzheimer cortex. Neuroscience. 1991; 42(3):651-60. PMID: 1956514.
    Citations: 11     Fields:    Translation:HumansCells
  119. Benes FM, Sorensen I, Bird ED. Reduced neuronal size in posterior hippocampus of schizophrenic patients. Schizophr Bull. 1991; 17(4):597-608. PMID: 1805353.
    Citations: 46     Fields:    Translation:HumansCells
  120. Woods BT, Yurgelun-Todd D, Benes FM, Frankenburg FR, Pope HG, McSparren J. Progressive ventricular enlargement in schizophrenia: comparison to bipolar affective disorder and correlation with clinical course. Biol Psychiatry. 1990 Feb 01; 27(3):341-52. PMID: 2302441.
    Citations: 5     Fields:    Translation:Humans
  121. Chou WG, Zain SB, Rehman S, Tate-Ostroff B, Majocha RE, Benes FM, Marotta CA. Alzheimer cortical neurons containing abundant amyloid mRNA. Relationship to amyloid deposition and senile plaques. J Psychiatr Res. 1990; 24(1):37-50. PMID: 2195164.
    Citations: 2     Fields:    Translation:HumansCells
  122. Benes FM, Vincent SL, San Giovanni JP. High resolution imaging of receptor binding in analyzing neuropsychiatric diseases. Biotechniques. 1989 Oct; 7(9):970-2, 974-6, 978. PMID: 2561064.
    Citations: 1     Fields:    Translation:Humans
  123. Rothschild AJ, Benes F, Hebben N, Woods B, Luciana M, Bakanas E, Samson JA, Schatzberg AF. Relationships between brain CT scan findings and cortisol in psychotic and nonpsychotic depressed patients. Biol Psychiatry. 1989 Oct; 26(6):565-75. PMID: 2790096.
    Citations: 15     Fields:    Translation:Humans
  124. Cohen BM, Benes FM, Baldessarini RJ. Atypical neuroleptics, dose-response relationships, and treatment-resistant psychosis. Arch Gen Psychiatry. 1989 Apr; 46(4):381-3. PMID: 2564764.
    Citations: 3     Fields:    Translation:Humans
  125. Benes FM, Reifel JL, Majocha RE, Marotta CA. Evidence for a diffusional model of Alzheimer amyloid A4 (beta-amyloid) deposition during neuritic plaque formation. Neuroscience. 1989; 33(3):483-8. PMID: 2700016.
    Citations: 6     Fields:    Translation:HumansCells
  126. Benes FM. Myelination of cortical-hippocampal relays during late adolescence. Schizophr Bull. 1989; 15(4):585-93. PMID: 2623440.
    Citations: 123     Fields:    Translation:HumansCells
  127. Cohen BM, Buonanno F, Keck PE, Finklestein SP, Benes FM. Comparison of MRI and CT scans in a group of psychiatric patients. Am J Psychiatry. 1988 Sep; 145(9):1084-8. PMID: 3414850.
    Citations: 1     Fields:    Translation:Humans
  128. Majocha RE, Benes FM, Reifel JL, Rodenrys AM, Marotta CA. Laminar-specific distribution and infrastructural detail of amyloid in the Alzheimer disease cortex visualized by computer-enhanced imaging of epitopes recognized by monoclonal antibodies. Proc Natl Acad Sci U S A. 1988 Aug; 85(16):6182-6. PMID: 2457908; PMCID: PMC281929.
    Citations: 21     Fields:    Translation:Humans
  129. Ionescu-Pioggia M, Bird M, Orzack MH, Benes F, Beake B, Cole JO. Methaqualone. Int Clin Psychopharmacol. 1988 Apr; 3(2):97-109. PMID: 3397524.
    Citations: 3     Fields:    Translation:Humans
  130. Benes FM, Majocha RE, Marotta CA. A modular arrangement of neuronal processes in human cortex: disruption with aging and in Alzheimer's disease. J Geriatr Psychiatry Neurol. 1988 Jan; 1(1):3-10. PMID: 3150925.
    Citations:    Fields:    Translation:HumansCells
  131. Benes FM. Post-mortem structural analyses of schizophrenic brain: study designs and the interpretation of data. Psychiatr Dev. 1988; 6(3):213-26. PMID: 3244701.
    Citations:    Fields:    Translation:Humans
  132. Benes FM, Matthysse SW, Davidson J, Bird ED. The spatial distribution of neurons and glia in human cortex based on the poisson distribution. Anal Quant Cytol Histol. 1987 Dec; 9(6):531-4. PMID: 3435629.
    Citations: 1     Fields:    Translation:HumansCells
  133. Benes FM, Majocha R, Bird ED, Marotta CA. Increased vertical axon numbers in cingulate cortex of schizophrenics. Arch Gen Psychiatry. 1987 Nov; 44(11):1017-21. PMID: 2445320.
    Citations: 25     Fields:    Translation:HumansCells
  134. Benes FM, Bird ED. An analysis of the arrangement of neurons in the cingulate cortex of schizophrenic patients. Arch Gen Psychiatry. 1987 Jul; 44(7):608-16. PMID: 3606326.
    Citations: 36     Fields:    Translation:HumansCells
  135. Benes FM, Davidson J, Bird ED. Quantitative cytoarchitectural studies of the cerebral cortex of schizophrenics. Arch Gen Psychiatry. 1986 Jan; 43(1):31-5. PMID: 3942472.
    Citations: 75     Fields:    Translation:HumansCells
  136. Benes FM, Paskevich PA, Davidson J, Domesick VB. Synaptic rearrangements in medial prefrontal cortex of haloperidol-treated rats. Brain Res. 1985 Nov 25; 348(1):15-20. PMID: 4063818.
    Citations: 12     Fields:    Translation:AnimalsCells
  137. Majocha RE, Marotta CA, Benes FM. Immunostaining of neurofilament protein in human postmortem cortex: a sensitive and specific approach to the pattern analysis of human cortical cytoarchitecture. Can J Biochem Cell Biol. 1985 Jun; 63(6):577-84. PMID: 3930053.
    Citations: 5     Fields:    Translation:HumansAnimals
  138. Benes FM, Paskevich PA, Davidson J, Domesick VB. The effects of haloperidol on synaptic patterns in the rat striatum. Brain Res. 1985 Mar 11; 329(1-2):265-73. PMID: 3978446.
    Citations: 30     Fields:    Translation:AnimalsCells
  139. Swigar ME, Benes FM, Rothman SL, Opsahl C, Dowds MM. Behavioral correlates of computed tomographic (CT) scan changes in older psychiatric patients. J Am Geriatr Soc. 1985 Feb; 33(2):96-103. PMID: 3968377.
    Citations: 2     Fields:    Translation:Humans
  140. Benes FM, Paskevich PA, Domesick VB. Haloperidol-induced plasticity of axon terminals in rat substantia nigra. Science. 1983 Sep 02; 221(4614):969-71. PMID: 6879197.
    Citations: 9     Fields:    Translation:AnimalsCells
  141. Benes FM, Swigar ME, Rothman SL, Opsahl C, Dowds M. CT scan studies of superficial cerebral regions: frequency and distribution of abnormalities in elderly psychiatric patients. Neurobiol Aging. 1983; 4(4):289-95. PMID: 6672638.
    Citations: 2     Fields:    Translation:Humans
  142. Benes F, Sunderland P, Jones BD, LeMay M, Cohen BM, Lipinski JF. Normal ventricles in young schizophrenics. Br J Psychiatry. 1982 Jul; 141:90-3. PMID: 6981446.
    Citations: 3     Fields:    Translation:Humans
  143. Benes FM, Barrnett RJ. Biochemical and morphometric studies of the relationship of acetylcholine synthesis and vesicle numbers after stimulation of frog neuromuscular junctions: the effect of a choline-O-acetyltransferase inhibitor. Brain Res. 1978 Jul 14; 150(2):277-93. PMID: 307974.
    Citations:    Fields:    Translation:AnimalsCells
  144. Benes FM, Parks TN, Rubel EW. Rapid dendritic atrophy following deafferentation: an EM morphometric analysis. Brain Res. 1977 Feb 11; 122(1):1-13. PMID: 837214.
    Citations: 21     Fields:    Translation:AnimalsCells
  145. Wulle KG, Cullmann B, Benes F, Giere W, Hoffmann J, Traunecker U. [Rational documentation of ophthalmological examinations (author's transl)]. Klin Monbl Augenheilkd. 1974 Jun; 164(6):829-37. PMID: 4421451.
    Citations:    Fields:    Translation:Humans
  146. Benes F, Higgins JA, Barrnett RJ. Ultrastructural localization of phospholipid synthesis in the rat trigeminal nerve during myelination. J Cell Biol. 1973 Jun; 57(3):613-29. PMID: 4349220; PMCID: PMC2108996.
    Citations: 5     Fields:    Translation:AnimalsCells
  147. Benes FM, Higgins JA, Barrnett RJ. Fine structural localization of acyltransferase activity in rat hepatocytes. J Histochem Cytochem. 1972 Dec; 20(12):1031-40. PMID: 4640963.
    Citations: 4     Fields:    Translation:Animals
  148. Benes F, Zícha B. [Tryptophan pyrrolase as a typical model of an adaptive enzyme]. Cesk Fysiol. 1968; 17(6):519-42. PMID: 4889850.
    Citations:    Fields:    Translation:HumansAnimals
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