Harvard Catalyst Profiles

Contact, publication, and social network information about Harvard faculty and fellows.

Steven W. Lockley, Ph.D.

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Research
research activities and funding
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
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  1. R21ES017112 (LOCKLEY, STEVEN W) Jul 1, 2009 - Jun 30, 2012
    NIH
    Effects of the circadian clock and light on the production of estrogens
    Role: Principal Investigator
  2. R01NS054277 (CZEISLER, CHARLES A) Feb 15, 2007 - Jan 31, 2014
    NIH
    Desensitization of Circadian Responses to Light
    Role: Co-Principal Investigator
  3. R01AT002129 (LOCKLEY, STEVEN W) Sep 15, 2004 - Jul 31, 2010
    NIH
    Mechanism Underlying the Effects of Blue Light in Humans
    Role: Principal Investigator
  4. R01NS040982 (LOCKLEY, STEVEN W) Dec 1, 2000 - Aug 31, 2010
    NIH
    Photic and Nonphotic Input to the Human Circadian System
    Role: Principal Investigator
  5. R01MH045130 (LOCKLEY, STEVEN W) Sep 1, 1989 - May 31, 2012
    NIH
    Treatment of Circadian Sleep Disorders with Bright Light
    Role: Principal Investigator

Bibliographic
selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. St Hilaire MA, Ámundadóttir ML, Rahman SA, Rajaratnam SMW, Rüger M, Brainard GC, Czeisler CA, Andersen M, Gooley JJ, Lockley SW. The spectral sensitivity of human circadian phase resetting and melatonin suppression to light changes dynamically with light duration. Proc Natl Acad Sci U S A. 2022 12 20; 119(51):e2205301119. PMID: 36508661; PMCID: PMC9907124.
    Citations: 3     Fields:    Translation:HumansCells
  2. Meyer N, Harvey AG, Lockley SW, Dijk DJ. Circadian rhythms and disorders of the timing of sleep. Lancet. 2022 09 24; 400(10357):1061-1078. PMID: 36115370.
    Citations: 3     Fields:    Translation:Humans
  3. Rahman SA, Kent BA, Grant LK, Clark T, Hanifin JP, Barger LK, Czeisler CA, Brainard GC, St Hilaire MA, Lockley SW. Effects of dynamic lighting on circadian phase, self-reported sleep and performance during a 45-day space analog mission with chronic variable sleep deficiency. J Pineal Res. 2022 Nov; 73(4):e12826. PMID: 35996978.
    Citations:    Fields:    Translation:Humans
  4. Hauptman M, Lockley SW, Landrigan CP. Invited Commentary: There's No Place Like Home-Integrating a Place-Based Approach to Understanding Sleep. Am J Epidemiol. 2022 08 22; 191(9):1540-1543. PMID: 35524716; PMCID: PMC9618158.
    Citations:    Fields:    
  5. Sletten TL, Sullivan JP, Arendt J, Palinkas LA, Barger LK, Fletcher L, Arnold M, Wallace J, Strauss C, Baker RJS, Kloza K, Kennaway DJ, Rajaratnam SMW, Ayton J, Lockley SW. The role of circadian phase in sleep and performance during Antarctic winter expeditions. J Pineal Res. 2022 Sep; 73(2):e12817. PMID: 35833316; PMCID: PMC9541096.
    Citations:    Fields:    
  6. Grant LK, St Hilaire MA, Heller JP, Heller RA, Lockley SW, Rahman SA. Impact of Upgraded Lighting on Falls in Care Home Residents. J Am Med Dir Assoc. 2022 10; 23(10):1698-1704.e2. PMID: 35850166.
    Citations:    Fields:    
  7. Rahman SA, St Hilaire MA, Grant LK, Barger LK, Brainard GC, Czeisler CA, Klerman EB, Lockley SW. Dynamic lighting schedules to facilitate circadian adaptation to shifted timing of sleep and wake. J Pineal Res. 2022 Aug; 73(1):e12805. PMID: 35501292.
    Citations:    Fields:    Translation:Humans
  8. Stone JE, Wiley J, Chachos E, Hand AJ, Lu S, Raniti M, Klerman E, Lockley SW, Carskadon MA, Phillips AJK, Bei B, Rajaratnam SMW. The CLASS Study (Circadian Light in Adolescence, Sleep and School): protocol for a prospective, longitudinal cohort to assess sleep, light, circadian timing and academic performance in adolescence. BMJ Open. 2022 05 10; 12(5):e055716. PMID: 35537785; PMCID: PMC9092183.
    Citations:    Fields:    Translation:HumansPHPublic Health
  9. Kent BA, Rahman SA, St Hilaire MA, Grant LK, Rüger M, Czeisler CA, Lockley SW. Publisher Correction: Circadian lipid and hepatic protein rhythms shift with a phase response curve different than melatonin. Nat Commun. 2022 Apr 20; 13(1):2241. PMID: 35444241; PMCID: PMC9021291.
    Citations:    Fields:    
  10. Booker LA, Sletten TL, Barnes M, Alvaro P, Collins A, Chai-Coetzer CL, McMahon M, Lockley SW, Rajaratnam SMW, Howard ME. The effectiveness of an individualized sleep and shift work education and coaching program to manage shift work disorder in nurses: a randomized controlled trial. J Clin Sleep Med. 2022 04 01; 18(4):1035-1045. PMID: 34870586; PMCID: PMC8974377.
    Citations:    Fields:    Translation:Humans
  11. Brown TM, Brainard GC, Cajochen C, Czeisler CA, Hanifin JP, Lockley SW, Lucas RJ, Münch M, O'Hagan JB, Peirson SN, Price LLA, Roenneberg T, Schlangen LJM, Skene DJ, Spitschan M, Vetter C, Zee PC, Wright KP. Recommendations for daytime, evening, and nighttime indoor light exposure to best support physiology, sleep, and wakefulness in healthy adults. PLoS Biol. 2022 03; 20(3):e3001571. PMID: 35298459; PMCID: PMC8929548.
    Citations: 3     Fields:    Translation:Humans
  12. Kent BA, Rahman SA, St Hilaire MA, Grant LK, Rüger M, Czeisler CA, Lockley SW. Circadian lipid and hepatic protein rhythms shift with a phase response curve different than melatonin. Nat Commun. 2022 02 03; 13(1):681. PMID: 35115537; PMCID: PMC8814172.
    Citations: 1     Fields:    Translation:Humans
  13. St Hilaire MA, Lockley SW. Measuring Dim Light Melatonin Onset in Humans. Methods Mol Biol. 2022; 2550:13-20. PMID: 36180672.
    Citations:    Fields:    Translation:Humans
  14. St Hilaire MA, Lockley SW. Measuring Urinary 6-Sulphatoxymelatonin in Humans. Methods Mol Biol. 2022; 2550:21-28. PMID: 36180673.
    Citations:    Fields:    Translation:Humans
  15. Knock SA, Magee M, Stone JE, Ganesan S, Mulhall MD, Lockley SW, Howard ME, Rajaratnam SMW, Sletten TL, Postnova S. Prediction of shiftworker alertness, sleep, and circadian phase using a model of arousal dynamics constrained by shift schedules and light exposure. Sleep. 2021 11 12; 44(11). PMID: 34111278; PMCID: PMC8598188.
    Citations: 1     Fields:    Translation:Humans
  16. Connolly LJ, Ponsford JL, Rajaratnam SMW, Lockley SW. Development of a Home-Based Light Therapy for Fatigue Following Traumatic Brain Injury: Two Case Studies. Front Neurol. 2021; 12:651498. PMID: 34589041.
    Citations: 1     
  17. Stone JE, Phillips AJK, Chachos E, Hand AJ, Lu S, Carskadon MA, Klerman EB, Lockley SW, Wiley JF, Bei B, Rajaratnam SMW. In-person vs home schooling during the COVID-19 pandemic: Differences in sleep, circadian timing, and mood in early adolescence. J Pineal Res. 2021 Sep; 71(2):e12757. PMID: 34273194; PMCID: PMC8420593.
    Citations: 4     Fields:    Translation:HumansCellsPHPublic Health
  18. Sides MB, Johnston SL, Sirek A, Lee PH, Blue RS, Antonsen EL, Basner M, Douglas GL, Epstein A, Flynn-Evans EE, Gallagher MB, Hayes J, Lee SMC, Lockley SW, Monseur B, Nelson NG, Sargsyan A, Smith SM, Stenger MB, Stepanek J, Zwart SR. Bellagio II Report: Terrestrial Applications of Space Medicine Research. Aerosp Med Hum Perform. 2021 Aug 01; 92(8):650-669. PMID: 34503618.
    Citations: 1     Fields:    Translation:Humans
  19. Connolly LJ, Rajaratnam SMW, Spitz G, Lockley SW, Ponsford JL. Factors Associated With Response to Pilot Home-Based Light Therapy for Fatigue Following Traumatic Brain Injury and Stroke. Front Neurol. 2021; 12:651392. PMID: 34335435.
    Citations:    
  20. Grant LK, St Hilaire MA, Brainard GC, Czeisler CA, Lockley SW, Rahman SA. Endogenous circadian regulation and phase resetting of clinical metabolic biomarkers. J Pineal Res. 2021 Sep; 71(2):e12752. PMID: 34118084.
    Citations: 2     Fields:    Translation:Humans
  21. Connolly LJ, Rajaratnam SMW, Murray JM, Spitz G, Lockley SW, Ponsford JL. Home-based light therapy for fatigue following acquired brain injury: a pilot randomized controlled trial. BMC Neurol. 2021 Jul 05; 21(1):262. PMID: 34225698.
    Citations: 3     Fields:    Translation:Humans
  22. Murray JM, Magee M, Sletten TL, Gordon C, Lovato N, Ambani K, Bartlett DJ, Kennaway DJ, Lack LC, Grunstein RR, Lockley SW, Rajaratnam SMW, Phillips AJK. Light-based methods for predicting circadian phase in delayed sleep-wake phase disorder. Sci Rep. 2021 05 25; 11(1):10878. PMID: 34035333; PMCID: PMC8149449.
    Citations: 1     Fields:    Translation:Humans
  23. Sletten TL, Raman B, Magee M, Ferguson SA, Kennaway DJ, Grunstein RR, Lockley SW, Rajaratnam SMW. A Blue-Enriched, Increased Intensity Light Intervention to Improve Alertness and Performance in Rotating Night Shift Workers in an Operational Setting. Nat Sci Sleep. 2021; 13:647-657. PMID: 34079409; PMCID: PMC8163632.
    Citations: 2     
  24. Bazzi LA, Sigurdardottir LG, Sigurdsson S, Valdimarsdottir U, Torfadottir J, Aspelund T, Czeisler CA, Lockley SW, Jonsson E, Launer L, Harris T, Gudnason V, Mucci LA, Markt SC. Exploratory assessment of pineal gland volume, composition, and urinary 6-sulfatoxymelatonin levels on prostate cancer risk. Prostate. 2021 06; 81(8):487-496. PMID: 33860950; PMCID: PMC8194005.
    Citations:    Fields:    Translation:Humans
  25. McMahon WR, Ftouni S, Diep C, Collet J, Lockley SW, Rajaratnam SMW, Maruff P, Drummond SPA, Anderson C. The impact of the wake maintenance zone on attentional capacity, physiological drowsiness, and subjective task demands during sleep deprivation. J Sleep Res. 2021 10; 30(5):e13312. PMID: 33734527.
    Citations:    Fields:    Translation:Humans
  26. Rahman SA, Brainard GC, Czeisler CA, Lockley SW. Spectral sensitivity of circadian phase resetting, melatonin suppression and acute alerting effects of intermittent light exposure. Biochem Pharmacol. 2021 09; 191:114504. PMID: 33711285.
    Citations: 1     Fields:    Translation:Humans
  27. Grant LK, Czeisler CA, Lockley SW, Rahman SA. Time-of-day and Meal Size Effects on Clinical Lipid Markers. J Clin Endocrinol Metab. 2021 Mar 08; 106(3):e1373-e1379. PMID: 34932808.
    Citations:    Fields:    
  28. Grant LK, Czeisler CA, Lockley SW, Rahman SA. Time-of-day and Meal Size Effects on Clinical Lipid Markers. J Clin Endocrinol Metab. 2021 03 08; 106(3):e1373-e1379. PMID: 33051649.
    Citations: 3     Fields:    Translation:HumansCTClinical Trials
  29. Grant LK, Kent BA, Mayer MD, Stickgold R, Lockley SW, Rahman SA. Daytime Exposure to Short Wavelength-Enriched Light Improves Cognitive Performance in Sleep-Restricted College-Aged Adults. Front Neurol. 2021; 12:624217. PMID: 33692742.
    Citations: 4     
  30. Rahman SA, Sullivan JP, Barger LK, St Hilaire MA, O'Brien CS, Stone KL, Phillips AJK, Klerman EB, Qadri S, Wright KP, Halbower AC, Segar JL, McGuire JK, Vitiello MV, de la Iglesia HO, Poynter SE, Yu PL, Sanderson AL, Zee PC, Landrigan CP, Czeisler CA, Lockley SW. Extended Work Shifts and Neurobehavioral Performance in Resident-Physicians. Pediatrics. 2021 03; 147(3). PMID: 33619044; PMCID: PMC7919117.
    Citations: 3     Fields:    Translation:HumansCTClinical Trials
  31. Barger LK, Sullivan JP, Lockley SW, Czeisler CA. Exposure to Short Wavelength-Enriched White Light and Exercise Improves Alertness and Performance in Operational NASA Flight Controllers Working Overnight Shifts. J Occup Environ Med. 2021 02 01; 63(2):111-118. PMID: 33065729.
    Citations: 4     Fields:    Translation:Humans
  32. Chen Y, Broman AT, Priest G, Landrigan CP, Rahman SA, Lockley SW. The Effect of Blue-Enriched Lighting on Medical Error Rate in a University Hospital ICU. Jt Comm J Qual Patient Saf. 2021 03; 47(3):165-175. PMID: 33341396.
    Citations: 1     Fields:    Translation:Humans
  33. Magee M, Sletten TL, Murray JM, Gordon CJ, Lovato N, Bartlett DJ, Kennaway DJ, Lockley SW, Lack LC, Grunstein RR, Archer SN, Rajaratnam SMW. A PERIOD3 variable number tandem repeat polymorphism modulates melatonin treatment response in delayed sleep-wake phase disorder. J Pineal Res. 2020 Nov; 69(4):e12684. PMID: 32682347.
    Citations: 3     Fields:    Translation:HumansCells
  34. McMahon WR, Ftouni S, Phillips AJK, Beatty C, Lockley SW, Rajaratnam SMW, Maruff P, Drummond SPA, Anderson C. The impact of structured sleep schedules prior to an in-laboratory study: Individual differences in sleep and circadian timing. PLoS One. 2020; 15(8):e0236566. PMID: 32785281; PMCID: PMC7423117.
    Citations: 2     Fields:    Translation:Humans
  35. Tekieh T, Lockley SW, Robinson PA, McCloskey S, Zobaer MS, Postnova S. Modeling melanopsin-mediated effects of light on circadian phase, melatonin suppression, and subjective sleepiness. J Pineal Res. 2020 Oct; 69(3):e12681. PMID: 32640090.
    Citations: 5     Fields:    Translation:Humans
  36. Landrigan CP, Rahman SA, Sullivan JP, Vittinghoff E, Barger LK, Sanderson AL, Wright KP, O'Brien CS, Qadri S, St Hilaire MA, Halbower AC, Segar JL, McGuire JK, Vitiello MV, de la Iglesia HO, Poynter SE, Yu PL, Zee PC, Lockley SW, Stone KL, Czeisler CA. Effect on Patient Safety of a Resident Physician Schedule without 24-Hour Shifts. N Engl J Med. 2020 06 25; 382(26):2514-2523. PMID: 32579812; PMCID: PMC7405505.
    Citations: 17     Fields:    Translation:Humans
  37. Lockley SW. Journal of Pineal Research guideline for authors: Measuring melatonin in humans. J Pineal Res. 2020 09; 69(2):e12664. PMID: 32344453.
    Citations: 5     Fields:    Translation:Humans
  38. Rahman SA, Rood D, Trent N, Solet J, Langer EJ, Lockley SW. Manipulating sleep duration perception changes cognitive performance - An exploratory analysis. J Psychosom Res. 2020 05; 132:109992. PMID: 32172039.
    Citations: 2     Fields:    Translation:Humans
  39. Grant LK, Gooley JJ, St Hilaire MA, Rajaratnam SMW, Brainard GC, Czeisler CA, Lockley SW, Rahman SA. Menstrual phase-dependent differences in neurobehavioral performance: the role of temperature and the progesterone/estradiol ratio. Sleep. 2020 02 13; 43(2). PMID: 31670824.
    Citations: 2     Fields:    Translation:Humans
  40. Booker LA, Barnes M, Alvaro P, Collins A, Chai-Coetzer CL, McMahon M, Lockley SW, Rajaratnam SMW, Howard ME, Sletten TL. The role of sleep hygiene in the risk of Shift Work Disorder in nurses. Sleep. 2020 02 13; 43(2). PMID: 31637435.
    Citations: 7     Fields:    Translation:Humans
  41. Rahman SA, Wright KP, Lockley SW, Czeisler CA, Gronfier C. Characterizing the temporal Dynamics of Melatonin and Cortisol Changes in Response to Nocturnal Light Exposure. Sci Rep. 2019 12 23; 9(1):19720. PMID: 31873098.
    Citations: 5     Fields:    Translation:HumansCTClinical Trials
  42. Vetter C, Phillips AJK, Silva A, Lockley SW, Glickman G. Light Me up? Why, When, and How Much Light We Need. J Biol Rhythms. 2019 12; 34(6):573-575. PMID: 31813350.
    Citations: 5     Fields:    Translation:HumansAnimals
  43. Peterson SA, Wolkow AP, Lockley SW, O'Brien CS, Qadri S, Sullivan JP, Czeisler CA, Rajaratnam SMW, Barger LK. Associations between shift work characteristics, shift work schedules, sleep and burnout in North American police officers: a cross-sectional study. BMJ Open. 2019 12 01; 9(11):e030302. PMID: 31791964.
    Citations: 9     Fields:    Translation:Humans
  44. Rahman SA, Grant LK, Gooley JJ, Rajaratnam SMW, Czeisler CA, Lockley SW. Endogenous Circadian Regulation of Female Reproductive Hormones. J Clin Endocrinol Metab. 2019 12 01; 104(12):6049-6059. PMID: 31415086; PMCID: PMC6821202.
    Citations: 15     Fields:    Translation:Humans
  45. St Hilaire MA, Kristal BS, Rahman SA, Sullivan JP, Quackenbush J, Duffy JF, Barger LK, Gooley JJ, Czeisler CA, Lockley SW. Using a Single Daytime Performance Test to Identify Most Individuals at High-Risk for Performance Impairment during Extended Wake. Sci Rep. 2019 11 13; 9(1):16681. PMID: 31723161.
    Citations: 7     Fields:    Translation:Humans
  46. Chua EC, Sullivan JP, Duffy JF, Klerman EB, Lockley SW, Kristal BS, Czeisler CA, Gooley JJ. Classifying attentional vulnerability to total sleep deprivation using baseline features of Psychomotor Vigilance Test performance. Sci Rep. 2019 08 20; 9(1):12102. PMID: 31431644.
    Citations: 7     Fields:    Translation:Humans
  47. Barger LK, Sullivan JP, Blackwell T, O'Brien CS, St Hilaire MA, Rahman SA, Phillips AJK, Qadri S, Wright KP, Segar JL, McGuire JK, Vitiello MV, de la Iglesia HO, Poynter SE, Yu PL, Zee P, Sanderson AL, Halbower AC, Lockley SW, Landrigan CP, Stone KL, Czeisler CA. Effects on resident work hours, sleep duration, and work experience in a randomized order safety trial evaluating resident-physician schedules (ROSTERS). Sleep. 2019 08 01; 42(8). PMID: 31106381.
    Citations: 7     Fields:    Translation:Humans
  48. Stone JE, Aubert XL, Maass H, Phillips AJK, Magee M, Howard ME, Lockley SW, Rajaratnam SMW, Sletten TL. Application of a Limit-Cycle Oscillator Model for Prediction of Circadian Phase in Rotating Night Shift Workers. Sci Rep. 2019 07 30; 9(1):11032. PMID: 31363110.
    Citations: 13     Fields:    Translation:Humans
  49. Stone JE, Phillips AJK, Ftouni S, Magee M, Howard M, Lockley SW, Sletten TL, Anderson C, Rajaratnam SMW, Postnova S. Generalizability of A Neural Network Model for Circadian Phase Prediction in Real-World Conditions. Sci Rep. 2019 07 29; 9(1):11001. PMID: 31358781.
    Citations: 8     Fields:    Translation:Humans
  50. Spitschan M, Stefani O, Blattner P, Gronfier C, Lockley SW, Lucas RJ. How to Report Light Exposure in Human Chronobiology and Sleep Research Experiments. Clocks Sleep. 2019 Jul 01; 1(3):280-289. PMID: 31281903.
    Citations: 24     
  51. Mulhall MD, Sletten TL, Magee M, Stone JE, Ganesan S, Collins A, Anderson C, Lockley SW, Howard ME, Rajaratnam SMW. Sleepiness and driving events in shift workers: the impact of circadian and homeostatic factors. Sleep. 2019 06 11; 42(6). PMID: 30882154.
    Citations: 11     Fields:    Translation:Humans
  52. Razavi P, Devore EE, Bajaj A, Lockley SW, Figueiro MG, Ricchiuti V, Gauderman WJ, Hankinson SE, Willett WC, Schernhammer ES. Shift Work, Chronotype, and Melatonin Rhythm in Nurses. Cancer Epidemiol Biomarkers Prev. 2019 07; 28(7):1177-1186. PMID: 31142495; PMCID: PMC6750706.
    Citations: 30     Fields:    Translation:Humans
  53. Booker LA, Sletten TL, Alvaro PK, Barnes M, Collins A, Chai-Coetzer CL, Naqvi A, McMahon M, Lockley SW, Rajaratnam SMW, Howard ME. Exploring the associations between shift work disorder, depression, anxiety and sick leave taken amongst nurses. J Sleep Res. 2020 06; 29(3):e12872. PMID: 31144389.
    Citations: 23     Fields:    Translation:Humans
  54. Phillips AJK, Vidafar P, Burns AC, McGlashan EM, Anderson C, Rajaratnam SMW, Lockley SW, Cain SW. High sensitivity and interindividual variability in the response of the human circadian system to evening light. Proc Natl Acad Sci U S A. 2019 06 11; 116(24):12019-12024. PMID: 31138694; PMCID: PMC6575863.
    Citations: 81     Fields:    Translation:Humans
  55. Wolkow AP, Barger LK, O'Brien CS, Sullivan JP, Qadri S, Lockley SW, Czeisler CA, Rajaratnam SMW. Associations between sleep disturbances, mental health outcomes and burnout in firefighters, and the mediating role of sleep during overnight work: A cross-sectional study. J Sleep Res. 2019 12; 28(6):e12869. PMID: 31131535.
    Citations: 9     Fields:    Translation:Humans
  56. St Hilaire MA, Anderson C, Anwar J, Sullivan JP, Cade BE, Flynn-Evans EE, Czeisler CA, Lockley SW. Brief (<4 hr) sleep episodes are insufficient for restoring performance in first-year resident physicians working overnight extended-duration work shifts. Sleep. 2019 05 01; 42(5). PMID: 30794317; PMCID: PMC6519906.
    Citations: 5     Fields:    Translation:Humans
  57. Chang AM, Duffy JF, Buxton OM, Lane JM, Aeschbach D, Anderson C, Bjonnes AC, Cain SW, Cohen DA, Frayling TM, Gooley JJ, Jones SE, Klerman EB, Lockley SW, Munch M, Rajaratnam SMW, Rueger M, Rutter MK, Santhi N, Scheuermaier K, Van Reen E, Weedon MN, Czeisler CA, Scheer FAJL, Saxena R. Chronotype Genetic Variant in PER2 is Associated with Intrinsic Circadian Period in Humans. Sci Rep. 2019 03 29; 9(1):5350. PMID: 30926824.
    Citations: 5     Fields:    Translation:Humans
  58. Murray JM, Phillips AJK, Magee M, Sletten TL, Gordon C, Lovato N, Bei B, Bartlett DJ, Kennaway DJ, Lack LC, Grunstein RR, Lockley SW, Rajaratnam SMW. Sleep regularity is associated with sleep-wake and circadian timing, and mediates daytime function in Delayed Sleep-Wake Phase Disorder. Sleep Med. 2019 06; 58:93-101. PMID: 31132578.
    Citations: 13     Fields:    Translation:Humans
  59. Blackwell T, Kriesel DR, Vittinghoff E, O'Brien CS, Sullivan JP, Viyaran NC, Rahman SA, Lockley SW, Barger LK, Halbower AC, Poynter SE, Wright KP, Yu PL, Zee PC, Landrigan CP, Czeisler CA, Stone KL. Design and recruitment of the randomized order safety trial evaluating resident-physician schedules (ROSTERS) study. Contemp Clin Trials. 2019 05; 80:22-33. PMID: 30885799.
    Citations: 3     Fields:    Translation:Humans
  60. Ganesan S, Magee M, Stone JE, Mulhall MD, Collins A, Howard ME, Lockley SW, Rajaratnam SMW, Sletten TL. The Impact of Shift Work on Sleep, Alertness and Performance in Healthcare Workers. Sci Rep. 2019 03 15; 9(1):4635. PMID: 30874565.
    Citations: 49     Fields:    Translation:Humans
  61. Grant LK, Ftouni S, Nijagal B, De Souza DP, Tull D, McConville MJ, Rajaratnam SMW, Lockley SW, Anderson C. Circadian and wake-dependent changes in human plasma polar metabolites during prolonged wakefulness: A preliminary analysis. Sci Rep. 2019 03 14; 9(1):4428. PMID: 30872634.
    Citations: 14     Fields:    Translation:Humans
  62. Vandewalle G, van Ackeren MJ, Daneault V, Hull JT, Albouy G, Lepore F, Doyon J, Czeisler CA, Dumont M, Carrier J, Lockley SW, Collignon O. Light modulates oscillatory alpha activity in the occipital cortex of totally visually blind individuals with intact non-image-forming photoreception. Sci Rep. 2018 11 16; 8(1):16968. PMID: 30446699.
    Citations: 4     Fields:    Translation:HumansCells
  63. Watson LA, Phillips AJK, Hosken IT, McGlashan EM, Anderson C, Lack LC, Lockley SW, Rajaratnam SMW, Cain SW. Increased sensitivity of the circadian system to light in delayed sleep-wake phase disorder. J Physiol. 2018 12; 596(24):6249-6261. PMID: 30281150; PMCID: PMC6292803.
    Citations: 14     Fields:    Translation:Humans
  64. Hanifin JP, Lockley SW, Cecil K, West K, Jablonski M, Warfield B, James M, Ayers M, Byrne B, Gerner E, Pineda C, Rollag M, Brainard GC. Randomized trial of polychromatic blue-enriched light for circadian phase shifting, melatonin suppression, and alerting responses. Physiol Behav. 2019 01 01; 198:57-66. PMID: 30296404.
    Citations: 11     Fields:    Translation:Humans
  65. McMahon WR, Ftouni S, Drummond SPA, Maruff P, Lockley SW, Rajaratnam SMW, Anderson C. The wake maintenance zone shows task dependent changes in cognitive function following one night without sleep. Sleep. 2018 10 01; 41(10). PMID: 30169703.
    Citations: 7     Fields:    Translation:Humans
  66. Ogeil RP, Barger LK, Lockley SW, O'Brien CS, Sullivan JP, Qadri S, Lubman DI, Czeisler CA, Rajaratnam SMW. Cross-sectional analysis of sleep-promoting and wake-promoting drug use on health, fatigue-related error, and near-crashes in police officers. BMJ Open. 2018 09 19; 8(9):e022041. PMID: 30232109.
    Citations: 4     Fields:    Translation:Humans
  67. Vidafar P, Gooley JJ, Burns AC, Rajaratnam SMW, Rueger M, Van Reen E, Czeisler CA, Lockley SW, Cain SW. Increased vulnerability to attentional failure during acute sleep deprivation in women depends on menstrual phase. Sleep. 2018 08 01; 41(8). PMID: 29790961.
    Citations: 13     Fields:    Translation:Humans
  68. Sletten TL, Magee M, Murray JM, Gordon CJ, Lovato N, Kennaway DJ, Gwini SM, Bartlett DJ, Lockley SW, Lack LC, Grunstein RR, Rajaratnam SMW. Efficacy of melatonin with behavioural sleep-wake scheduling for delayed sleep-wake phase disorder: A double-blind, randomised clinical trial. PLoS Med. 2018 06; 15(6):e1002587. PMID: 29912983.
    Citations: 19     Fields:    Translation:Humans
  69. Rahman SA, St Hilaire MA, Gronfier C, Chang AM, Santhi N, Czeisler CA, Klerman EB, Lockley SW. Functional decoupling of melatonin suppression and circadian phase resetting in humans. J Physiol. 2018 06; 596(11):2147-2157. PMID: 29707782; PMCID: PMC5983136.
    Citations: 18     Fields:    Translation:Humans
  70. Stone JE, Sletten TL, Magee M, Ganesan S, Mulhall MD, Collins A, Howard M, Lockley SW, Rajaratnam SMW. Temporal dynamics of circadian phase shifting response to consecutive night shifts in healthcare workers: role of light-dark exposure. J Physiol. 2018 06; 596(12):2381-2395. PMID: 29589871; PMCID: PMC6002215.
    Citations: 24     Fields:    Translation:Humans
  71. Hull JT, Czeisler CA, Lockley SW. Suppression of Melatonin Secretion in Totally Visually Blind People by Ocular Exposure to White Light: Clinical Characteristics. Ophthalmology. 2018 08; 125(8):1160-1171. PMID: 29625838.
    Citations: 14     Fields:    Translation:HumansCells
  72. Postnova S, Lockley SW, Robinson PA. Prediction of Cognitive Performance and Subjective Sleepiness Using a Model of Arousal Dynamics. J Biol Rhythms. 2018 04; 33(2):203-218. PMID: 29671707.
    Citations: 8     Fields:    Translation:Humans
  73. Abeysuriya RG, Lockley SW, Robinson PA, Postnova S. A unified model of melatonin, 6-sulfatoxymelatonin, and sleep dynamics. J Pineal Res. 2018 May; 64(4):e12474. PMID: 29437238.
    Citations: 25     Fields:    Translation:Humans
  74. Anderson C, Ftouni S, Ronda JM, Rajaratnam SMW, Czeisler CA, Lockley SW. Self-reported Drowsiness and Safety Outcomes While Driving After an Extended Duration Work Shift in Trainee Physicians. Sleep. 2018 Feb 01; 41(2). PMID: 29281091.
    Citations: 4     Fields:    
  75. St Hilaire MA, Rahman SA, Gooley JJ, Witt-Enderby PA, Lockley SW. Relationship between melatonin and bone resorption rhythms in premenopausal women. J Bone Miner Metab. 2019 Jan; 37(1):60-71. PMID: 29318392.
    Citations: 8     Fields:    Translation:Humans
  76. Kelley P, Lockley SW, Kelley J, Evans MDR. Is 8:30 a.m. Still Too Early to Start School? A 10:00 a.m. School Start Time Improves Health and Performance of Students Aged 13-16. Front Hum Neurosci. 2017; 11:588. PMID: 29276481; PMCID: PMC5727052.
    Citations: 7     
  77. Cohen S, Fulcher BD, Rajaratnam SMW, Conduit R, Sullivan JP, St Hilaire MA, Phillips AJK, Loddenkemper T, Kothare SV, McConnell K, Braga-Kenyon P, Ahearn W, Shlesinger A, Potter J, Bird F, Cornish KM, Lockley SW. Sleep patterns predictive of daytime challenging behavior in individuals with low-functioning autism. Autism Res. 2018 02; 11(2):391-403. PMID: 29197172.
    Citations: 24     Fields:    Translation:Humans
  78. Flynn-Evans EE, Shekleton JA, Miller B, Epstein LJ, Kirsch D, Brogna LA, Burke LM, Bremer E, Murray JM, Gehrman P, Rajaratnam SMW, Lockley SW. Circadian Phase and Phase Angle Disorders in Primary Insomnia. Sleep. 2017 12 01; 40(12). PMID: 29029340.
    Citations: 16     Fields:    Translation:Humans
  79. Cohen S, Fulcher BD, Rajaratnam SMW, Conduit R, Sullivan JP, Hilaire MAS, Phillips AJ, Loddenkemper T, Kothare SV, McConnell K, Ahearn W, Braga-Kenyon P, Shlesinger A, Potter J, Bird F, Cornish KM, Lockley SW. Behaviorally-determined sleep phenotypes are robustly associated with adaptive functioning in individuals with low functioning autism. Sci Rep. 2017 10 27; 7(1):14228. PMID: 29079761.
    Citations: 7     Fields:    Translation:Humans
  80. Lee CJ, Nolan DM, Lockley SW, Pattison B. Law-based arguments and messages to advocate for later school start time policies in the United States. Sleep Health. 2017 12; 3(6):486-497. PMID: 29157645.
    Citations: 1     Fields:    Translation:Humans
  81. Sletten TL, Ftouni S, Nicholas CL, Magee M, Grunstein RR, Ferguson S, Kennaway DJ, O'Brien D, Lockley SW, Rajaratnam SMW. Randomised controlled trial of the efficacy of a blue-enriched light intervention to improve alertness and performance in night shift workers. Occup Environ Med. 2017 11; 74(11):792-801. PMID: 28630378.
    Citations: 15     Fields:    Translation:Humans
  82. Phillips AJK, Clerx WM, O'Brien CS, Sano A, Barger LK, Picard RW, Lockley SW, Klerman EB, Czeisler CA. Irregular sleep/wake patterns are associated with poorer academic performance and delayed circadian and sleep/wake timing. Sci Rep. 2017 06 12; 7(1):3216. PMID: 28607474; PMCID: PMC5468315.
    Citations: 104     Fields:    Translation:Humans
  83. Rahman SA, St Hilaire MA, Lockley SW. The effects of spectral tuning of evening ambient light on melatonin suppression, alertness and sleep. Physiol Behav. 2017 Aug 01; 177:221-229. PMID: 28472667; PMCID: PMC5536841.
    Citations: 34     Fields:    Translation:Humans
  84. Rahman SA, St Hilaire MA, Chang AM, Santhi N, Duffy JF, Kronauer RE, Czeisler CA, Lockley SW, Klerman EB. Circadian phase resetting by a single short-duration light exposure. JCI Insight. 2017 04 06; 2(7):e89494. PMID: 28405608.
    Citations: 16     Fields:    Translation:HumansCTClinical Trials
  85. Newman DP, Lockley SW, Loughnane GM, Martins AC, Abe R, Zoratti MT, Kelly SP, O'Neill MH, Rajaratnam SM, O'Connell RG, Bellgrove MA. Corrigendum: Ocular exposure to blue-enriched light has an asymmetric influence on neural activity and spatial attention. Sci Rep. 2017 03 23; 7:44958. PMID: 28332565.
    Citations:    Fields:    
  86. Sullivan JP, O'Brien CS, Barger LK, Rajaratnam SM, Czeisler CA, Lockley SW. Randomized, Prospective Study of the Impact of a Sleep Health Program on Firefighter Injury and Disability. Sleep. 2017 Jan 01; 40(1). PMID: 28364446.
    Citations: 20     Fields:    Translation:Humans
  87. Murray JM, Sletten TL, Magee M, Gordon C, Lovato N, Bartlett DJ, Kennaway DJ, Lack LC, Grunstein RR, Lockley SW, Rajaratnam SM. Prevalence of Circadian Misalignment and Its Association With Depressive Symptoms in Delayed Sleep Phase Disorder. Sleep. 2017 Jan 01; 40(1). PMID: 28364473.
    Citations: 41     Fields:    Translation:Humans
  88. St Hilaire MA, Rüger M, Fratelli F, Hull JT, Phillips AJ, Lockley SW. Modeling Neurocognitive Decline and Recovery During Repeated Cycles of Extended Sleep and Chronic Sleep Deficiency. Sleep. 2017 Jan 01; 40(1). PMID: 28364449.
    Citations: 17     Fields:    Translation:HumansCTClinical Trials
  89. St Hilaire MA, Rüger M, Fratelli F, Hull JT, Phillips AJ, Lockley SW. Modeling neurocognitive decline and recovery during repeated cycles of extended sleep and chronic sleep deficiency. Sleep. 2016 Sep 26. PMID: 27692052.
    Citations:    
  90. Sullivan JP, O'Brien CS, Barger LK, Rajaratnam SM, Czeisler CA, Lockley SW. Randomized, prospective study of the impact of a sleep health program on firefighter injury and disability. Sleep. 2016 Sep 26. PMID: 27692049.
    Citations:    
  91. Murray JM, Sletten TL, Magee M, Gordon C, Lovato N, Bartlett DJ, Kennaway DJ, Lack LC, Grunstein RR, Lockley SW, Rajaratnam SM. Prevalence of Circadian Misalignment and Its Association with Depressive Symptoms in Delayed Sleep Phase Disorder. Sleep. 2016 Sep 26. PMID: 27692050.
    Citations:    
  92. Bullock B, Murray G, Anderson JL, Cooper-O'Neill T, Gooley JJ, Cain SW, Lockley SW. Constraint is associated with earlier circadian phase and morningness: Confirmation of relationships between personality and circadian phase using a constant routine protocol. Pers Individ Dif. 2017 Jan; 104:69-74. PMID: 28216802.
    Citations: 2     
  93. Segal AY, Sletten TL, Flynn-Evans EE, Lockley SW, Rajaratnam SM. Daytime Exposure to Short- and Medium-Wavelength Light Did Not Improve Alertness and Neurobehavioral Performance. J Biol Rhythms. 2016 10; 31(5):470-82. PMID: 27474192.
    Citations: 9     Fields:    Translation:HumansCells
  94. Sigurdardottir LG, Markt SC, Sigurdsson S, Aspelund T, Fall K, Schernhammer E, Rider JR, Launer L, Harris T, Stampfer MJ, Gudnason V, Czeisler CA, Lockley SW, Valdimarsdottir UA, Mucci LA. Pineal Gland Volume Assessed by MRI and Its Correlation with 6-Sulfatoxymelatonin Levels among Older Men. J Biol Rhythms. 2016 10; 31(5):461-9. PMID: 27449477; PMCID: PMC5393913.
    Citations: 12     Fields:    Translation:Humans
  95. Postnova S, Lockley SW, Robinson PA. Sleep Propensity under Forced Desynchrony in a Model of Arousal State Dynamics. J Biol Rhythms. 2016 10; 31(5):498-508. PMID: 27432116.
    Citations: 4     Fields:    Translation:Humans
  96. Newman DP, Lockley SW, Loughnane GM, Martins AC, Abe R, Zoratti MT, Kelly SP, O'Neill MH, Rajaratnam SM, O'Connell RG, Bellgrove MA. Ocular exposure to blue-enriched light has an asymmetric influence on neural activity and spatial attention. Sci Rep. 2016 06 13; 6:27754. PMID: 27291291.
    Citations: 9     Fields:    Translation:HumansCells
  97. Barger LK, O'Brien CS, Rajaratnam SM, Qadri S, Sullivan JP, Wang W, Czeisler CA, Lockley SW. Implementing a Sleep Health Education and Sleep Disorders Screening Program in Fire Departments: A Comparison of Methodology. J Occup Environ Med. 2016 06; 58(6):601-9. PMID: 27035103; PMCID: PMC4883642.
    Citations: 7     Fields:    Translation:Humans
  98. Flynn-Evans EE, Lockley SW. A Pre-Screening Questionnaire to Predict Non-24-Hour Sleep-Wake Rhythm Disorder (N24HSWD) among the Blind. J Clin Sleep Med. 2016 05 15; 12(5):703-10. PMID: 26951421.
    Citations: 4     Fields:    Translation:Humans
  99. Chang AM, Bjonnes AC, Aeschbach D, Buxton OM, Gooley JJ, Anderson C, Van Reen E, Cain SW, Czeisler CA, Duffy JF, Lockley SW, Shea SA, Scheer FA, Saxena R. Circadian gene variants influence sleep and the sleep electroencephalogram in humans. Chronobiol Int. 2016; 33(5):561-73. PMID: 27089043; PMCID: PMC5267557.
    Citations: 4     Fields:    Translation:Humans
  100. Magee M, Sletten TL, Ferguson SA, Grunstein RR, Anderson C, Kennaway DJ, Lockley SW, Rajaratnam SM. Associations between number of consecutive night shifts and impairment of neurobehavioral performance during a subsequent simulated night shift. Scand J Work Environ Health. 2016 05 01; 42(3):217-27. PMID: 27064758.
    Citations: 9     Fields:    Translation:Humans
  101. Lane JM, Chang AM, Bjonnes AC, Aeschbach D, Anderson C, Cade BE, Cain SW, Czeisler CA, Gharib SA, Gooley JJ, Gottlieb DJ, Grant SF, Klerman EB, Lauderdale DS, Lockley SW, Munch M, Patel S, Punjabi NM, Rajaratnam SM, Rueger M, St Hilaire MA, Santhi N, Scheuermaier K, Van Reen E, Zee PC, Shea SA, Duffy JF, Buxton OM, Redline S, Scheer FA, Saxena R. Impact of Common Diabetes Risk Variant in MTNR1B on Sleep, Circadian, and Melatonin Physiology. Diabetes. 2016 06; 65(6):1741-51. PMID: 26868293; PMCID: PMC4878414.
    Citations: 33     Fields:    Translation:Humans
  102. Markt SC, Flynn-Evans EE, Valdimarsdottir UA, Sigurdardottir LG, Tamimi RM, Batista JL, Haneuse S, Lockley SW, Stampfer M, Wilson KM, Czeisler CA, Rider JR, Mucci LA. Sleep Duration and Disruption and Prostate Cancer Risk: a 23-Year Prospective Study. Cancer Epidemiol Biomarkers Prev. 2016 Feb; 25(2):302-8. PMID: 26677208; PMCID: PMC4767658.
    Citations: 14     Fields:    Translation:Humans
  103. Uchiyama M, Lockley SW. Non-24-Hour Sleep-Wake Rhythm Disorder in Sighted and Blind Patients. Sleep Med Clin. 2015 Dec; 10(4):495-516. PMID: 26568125.
    Citations: 14     Fields:    Translation:Humans
  104. Ftouni S, Sletten TL, Nicholas CL, Kennaway DJ, Lockley SW, Rajaratnam SM. Ocular Measures of Sleepiness Are Increased in Night Shift Workers Undergoing a Simulated Night Shift Near the Peak Time of the 6-Sulfatoxymelatonin Rhythm. J Clin Sleep Med. 2015 Oct 15; 11(10):1131-41. PMID: 26094925.
    Citations: 5     Fields:    Translation:Humans
  105. Lockley SW, Dressman MA, Licamele L, Xiao C, Fisher DM, Flynn-Evans EE, Hull JT, Torres R, Lavedan C, Polymeropoulos MH. Tasimelteon for non-24-hour sleep-wake disorder in totally blind people (SET and RESET): two multicentre, randomised, double-masked, placebo-controlled phase 3 trials. Lancet. 2015 Oct 31; 386(10005):1754-64. PMID: 26466871.
    Citations: 37     Fields:    Translation:Humans
  106. Sletten TL, Segal AY, Flynn-Evans EE, Lockley SW, Rajaratnam SM. Inter-Individual Differences in Neurobehavioural Impairment following Sleep Restriction Are Associated with Circadian Rhythm Phase. PLoS One. 2015; 10(6):e0128273. PMID: 26043207.
    Citations: 7     Fields:    Translation:Humans
  107. Barger LK, Rajaratnam SM, Wang W, O'Brien CS, Sullivan JP, Qadri S, Lockley SW, Czeisler CA. Common sleep disorders increase risk of motor vehicle crashes and adverse health outcomes in firefighters. J Clin Sleep Med. 2015 Mar 15; 11(3):233-40. PMID: 25580602.
    Citations: 32     Fields:    Translation:Humans
  108. St Hilaire MA, Lockley SW. Caffeine does not entrain the circadian clock but improves daytime alertness in blind patients with non-24-hour rhythms. Sleep Med. 2015 Jun; 16(6):800-4. PMID: 25891543; PMCID: PMC4465963.
    Citations: 5     Fields:    Translation:Humans
  109. Cohen S, Conduit R, Lockley SW, Rajaratnam SM, Cornish KM. The relationship between sleep and behavior in autism spectrum disorder (ASD): a review. J Neurodev Disord. 2014; 6(1):44. PMID: 25530819.
    Citations: 86     Fields:    
  110. Rahman SA, Castanon-Cervantes O, Scheer FA, Shea SA, Czeisler CA, Davidson AJ, Lockley SW. Endogenous circadian regulation of pro-inflammatory cytokines and chemokines in the presence of bacterial lipopolysaccharide in humans. Brain Behav Immun. 2015 Jul; 47:4-13. PMID: 25452149; PMCID: PMC4430446.
    Citations: 30     Fields:    Translation:Humans
  111. Markt SC, Valdimarsdottir UA, Shui IM, Sigurdardottir LG, Rider JR, Tamimi RM, Batista JL, Haneuse S, Flynn-Evans E, Lockley SW, Czeisler CA, Stampfer MJ, Launer L, Harris T, Smith AV, Gudnason V, Lindstrom S, Kraft P, Mucci LA. Circadian clock genes and risk of fatal prostate cancer. Cancer Causes Control. 2015 Jan; 26(1):25-33. PMID: 25388799; PMCID: PMC4282953.
    Citations: 21     Fields:    Translation:Humans
  112. Sigurdardottir LG, Markt SC, Rider JR, Haneuse S, Fall K, Schernhammer ES, Tamimi RM, Flynn-Evans E, Batista JL, Launer L, Harris T, Aspelund T, Stampfer MJ, Gudnason V, Czeisler CA, Lockley SW, Valdimarsdottir UA, Mucci LA. Urinary melatonin levels, sleep disruption, and risk of prostate cancer in elderly men. Eur Urol. 2015 Feb; 67(2):191-4. PMID: 25107635.
    Citations: 39     Fields:    Translation:HumansCells
  113. Flynn-Evans EE, Tabandeh H, Skene DJ, Lockley SW. Circadian Rhythm Disorders and Melatonin Production in 127 Blind Women with and without Light Perception. J Biol Rhythms. 2014 Jun; 29(3):215-224. PMID: 24916394.
    Citations: 19     Fields:    
  114. Rahman SA, Flynn-Evans EE, Aeschbach D, Brainard GC, Czeisler CA, Lockley SW. Diurnal spectral sensitivity of the acute alerting effects of light. Sleep. 2014 Feb 01; 37(2):271-81. PMID: 24501435.
    Citations: 63     Fields:    Translation:Humans
  115. Shekleton JA, Flynn-Evans EE, Miller B, Epstein LJ, Kirsch D, Brogna LA, Burke LM, Bremer E, Murray JM, Gehrman P, Lockley SW, Rajaratnam SM. Neurobehavioral performance impairment in insomnia: relationships with self-reported sleep and daytime functioning. Sleep. 2014 Jan 01; 37(1):107-16. PMID: 24470700.
    Citations: 27     Fields:    Translation:Humans
  116. Stevens RG, Brainard GC, Blask DE, Lockley SW, Motta ME. Breast cancer and circadian disruption from electric lighting in the modern world. CA Cancer J Clin. 2014 May-Jun; 64(3):207-18. PMID: 24604162; PMCID: PMC4038658.
    Citations: 92     Fields:    Translation:Humans
  117. Ftouni S, Rahman SA, Crowley KE, Anderson C, Rajaratnam SM, Lockley SW. Temporal dynamics of ocular indicators of sleepiness across sleep restriction. J Biol Rhythms. 2013 Dec; 28(6):412-24. PMID: 24336419.
    Citations: 6     Fields:    Translation:Humans
  118. Lucas RJ, Peirson SN, Berson DM, Brown TM, Cooper HM, Czeisler CA, Figueiro MG, Gamlin PD, Lockley SW, O'Hagan JB, Price LL, Provencio I, Skene DJ, Brainard GC. Measuring and using light in the melanopsin age. Trends Neurosci. 2014 Jan; 37(1):1-9. PMID: 24287308; PMCID: PMC4699304.
    Citations: 242     Fields:    Translation:HumansAnimalsCells
  119. Sinclair KL, Ponsford JL, Taffe J, Lockley SW, Rajaratnam SM. Randomized controlled trial of light therapy for fatigue following traumatic brain injury. Neurorehabil Neural Repair. 2014 May; 28(4):303-13. PMID: 24213962.
    Citations: 29     Fields:    Translation:Humans
  120. Stevens RG, Brainard GC, Blask DE, Lockley SW, Motta ME. Adverse health effects of nighttime lighting: comments on American Medical Association policy statement. Am J Prev Med. 2013 Sep; 45(3):343-6. PMID: 23953362.
    Citations: 42     Fields:    Translation:Humans
  121. Flynn-Evans EE, Mucci L, Stevens RG, Lockley SW. Shiftwork and prostate-specific antigen in the National Health and Nutrition Examination Survey. J Natl Cancer Inst. 2013 Sep 04; 105(17):1292-7. PMID: 23943864.
    Citations: 35     Fields:    Translation:HumansPHPublic Health
  122. Vandewalle G, Collignon O, Hull JT, Daneault V, Albouy G, Lepore F, Phillips C, Doyon J, Czeisler CA, Dumont M, Lockley SW, Carrier J. Blue light stimulates cognitive brain activity in visually blind individuals. J Cogn Neurosci. 2013 Dec; 25(12):2072-85. PMID: 23859643.
    Citations: 34     Fields:    Translation:Humans
  123. Sigurdardottir LG, Valdimarsdottir UA, Mucci LA, Fall K, Rider JR, Schernhammer E, Czeisler CA, Launer L, Harris T, Stampfer MJ, Gudnason V, Lockley SW. Sleep disruption among older men and risk of prostate cancer. Cancer Epidemiol Biomarkers Prev. 2013 May; 22(5):872-9. PMID: 23652374.
    Citations: 31     Fields:    Translation:Humans
  124. Shekleton JA, Rajaratnam SM, Gooley JJ, Van Reen E, Czeisler CA, Lockley SW. Improved neurobehavioral performance during the wake maintenance zone. J Clin Sleep Med. 2013 Apr 15; 9(4):353-62. PMID: 23585751.
    Citations: 14     Fields:    Translation:Humans
  125. Crowley KE, Rajaratnam SM, Shea SA, Epstein LJ, Czeisler CA, Lockley SW. Evaluation of a single-channel nasal pressure device to assess obstructive sleep apnea risk in laboratory and home environments. J Clin Sleep Med. 2013 Feb 01; 9(2):109-16. PMID: 23372462.
    Citations: 17     Fields:    Translation:Humans
  126. Rüger M, St Hilaire MA, Brainard GC, Khalsa SB, Kronauer RE, Czeisler CA, Lockley SW. Human phase response curve to a single 6.5 h pulse of short-wavelength light. J Physiol. 2013 Jan 01; 591(1):353-63. PMID: 23090946.
    Citations: 46     Fields:    Translation:Humans
  127. Gooley JJ, Ho Mien I, St Hilaire MA, Yeo SC, Chua EC, van Reen E, Hanley CJ, Hull JT, Czeisler CA, Lockley SW. Melanopsin and rod-cone photoreceptors play different roles in mediating pupillary light responses during exposure to continuous light in humans. J Neurosci. 2012 Oct 10; 32(41):14242-53. PMID: 23055493.
    Citations: 85     Fields:    Translation:HumansCells
  128. Barger LK, Sullivan JP, Vincent AS, Fiedler ER, McKenna LM, Flynn-Evans EE, Gilliland K, Sipes WE, Smith PH, Brainard GC, Lockley SW. Learning to live on a Mars day: fatigue countermeasures during the Phoenix Mars Lander mission. Sleep. 2012 Oct 01; 35(10):1423-35. PMID: 23024441.
    Citations: 13     Fields:    Translation:Humans
  129. St Hilaire MA, Sullivan JP, Anderson C, Cohen DA, Barger LK, Lockley SW, Klerman EB. Classifying performance impairment in response to sleep loss using pattern recognition algorithms on single session testing. Accid Anal Prev. 2013 Jan; 50:992-1002. PMID: 22959616.
    Citations: 2     Fields:    Translation:Humans
  130. Ftouni S, Sletten TL, Howard M, Anderson C, Lenné MG, Lockley SW, Rajaratnam SM. Objective and subjective measures of sleepiness, and their associations with on-road driving events in shift workers. J Sleep Res. 2013 Feb; 22(1):58-69. PMID: 22861524.
    Citations: 34     Fields:    Translation:Humans
  131. Anderson C, Sullivan JP, Flynn-Evans EE, Cade BE, Czeisler CA, Lockley SW. Deterioration of neurobehavioral performance in resident physicians during repeated exposure to extended duration work shifts. Sleep. 2012 Aug 01; 35(8):1137-46. PMID: 22851809.
    Citations: 30     Fields:    Translation:Humans
  132. Sigurdardottir LG, Valdimarsdottir UA, Fall K, Rider JR, Lockley SW, Schernhammer E, Mucci LA. Circadian disruption, sleep loss, and prostate cancer risk: a systematic review of epidemiologic studies. Cancer Epidemiol Biomarkers Prev. 2012 Jul; 21(7):1002-11. PMID: 22564869.
    Citations: 53     Fields:    Translation:HumansAnimals
  133. St Hilaire MA, Gooley JJ, Khalsa SB, Kronauer RE, Czeisler CA, Lockley SW. Human phase response curve to a 1 h pulse of bright white light. J Physiol. 2012 Jul 01; 590(13):3035-45. PMID: 22547633.
    Citations: 79     Fields:    Translation:Humans
  134. Chang AM, Santhi N, St Hilaire M, Gronfier C, Bradstreet DS, Duffy JF, Lockley SW, Kronauer RE, Czeisler CA. Human responses to bright light of different durations. J Physiol. 2012 Jul 01; 590(13):3103-12. PMID: 22526883.
    Citations: 78     Fields:    Translation:Humans
  135. Klerman H, St Hilaire MA, Kronauer RE, Gooley JJ, Gronfier C, Hull JT, Lockley SW, Santhi N, Wang W, Klerman EB. Analysis method and experimental conditions affect computed circadian phase from melatonin data. PLoS One. 2012; 7(4):e33836. PMID: 22511928.
    Citations: 10     Fields:    Translation:Humans
  136. Sigurdardottir L, Valdimarsdottir UA, Mucci L, Fall K, Rider JR, Schernhammer ES, Czeisler CA, Launer L, Harris TB, Stampfer MJ, Gudnason V, Lockley SW. Insomnia among elderly men and risk of prostate cancer. J Clin Oncol. 2012 Feb 10; 30(5_suppl):78. PMID: 28142941.
    Citations:    
  137. Rajaratnam SM, Barger LK, Lockley SW, Shea SA, Wang W, Landrigan CP, O'Brien CS, Qadri S, Sullivan JP, Cade BE, Epstein LJ, White DP, Czeisler CA. Sleep disorders, health, and safety in police officers. JAMA. 2011 Dec 21; 306(23):2567-78. PMID: 22187276.
    Citations: 114     Fields:    Translation:Humans
  138. Bajaj A, Rosner B, Lockley SW, Schernhammer ES. Validation of a light questionnaire with real-life photopic illuminance measurements: the Harvard Light Exposure Assessment questionnaire. Cancer Epidemiol Biomarkers Prev. 2011 Jul; 20(7):1341-9. PMID: 21737411.
    Citations: 8     Fields:    Translation:Humans
  139. Loddenkemper T, Lockley SW, Kaleyias J, Kothare SV. Chronobiology of epilepsy: diagnostic and therapeutic implications of chrono-epileptology. J Clin Neurophysiol. 2011 Apr; 28(2):146-53. PMID: 21399517.
    Citations: 19     Fields:    Translation:Humans
  140. Gooley JJ, Chamberlain K, Smith KA, Khalsa SB, Rajaratnam SM, Van Reen E, Zeitzer JM, Czeisler CA, Lockley SW. Exposure to room light before bedtime suppresses melatonin onset and shortens melatonin duration in humans. J Clin Endocrinol Metab. 2011 Mar; 96(3):E463-72. PMID: 21193540; PMCID: PMC3047226.
    Citations: 121     Fields:    Translation:Humans
  141. Sletten TL, Vincenzi S, Redman JR, Lockley SW, Rajaratnam SM. Timing of sleep and its relationship with the endogenous melatonin rhythm. Front Neurol. 2010; 1:137. PMID: 21188265.
    Citations: 28     
  142. Pagani L, Semenova EA, Moriggi E, Revell VL, Hack LM, Lockley SW, Arendt J, Skene DJ, Meier F, Izakovic J, Wirz-Justice A, Cajochen C, Sergeeva OJ, Cheresiz SV, Danilenko KV, Eckert A, Brown SA. The physiological period length of the human circadian clock in vivo is directly proportional to period in human fibroblasts. PLoS One. 2010 Oct 15; 5(10):e13376. PMID: 21042402.
    Citations: 42     Fields:    Translation:HumansCells
  143. Gordon JA, Alexander EK, Lockley SW, Flynn-Evans E, Venkatan SK, Landrigan CP, Czeisler CA. Does simulator-based clinical performance correlate with actual hospital behavior? The effect of extended work hours on patient care provided by medical interns. Acad Med. 2010 Oct; 85(10):1583-8. PMID: 20881679; PMCID: PMC3754850.
    Citations: 9     Fields:    Translation:Humans
  144. Jung CM, Khalsa SB, Scheer FA, Cajochen C, Lockley SW, Czeisler CA, Wright KP. Acute effects of bright light exposure on cortisol levels. J Biol Rhythms. 2010 Jun; 25(3):208-16. PMID: 20484692.
    Citations: 53     Fields:    Translation:Humans
  145. Gooley JJ, Rajaratnam SM, Brainard GC, Kronauer RE, Czeisler CA, Lockley SW. Spectral responses of the human circadian system depend on the irradiance and duration of exposure to light. Sci Transl Med. 2010 May 12; 2(31):31ra33. PMID: 20463367.
    Citations: 119     Fields:    Translation:HumansCells
  146. Flynn-Evans EE, Stevens RG, Tabandeh H, Schernhammer ES, Lockley SW. Total visual blindness is protective against breast cancer. Cancer Causes Control. 2009 Nov; 20(9):1753-6. PMID: 19649715.
    Citations: 30     Fields:    Translation:Humans
  147. Aeschbach D, Lockyer BJ, Dijk DJ, Lockley SW, Nuwayser ES, Nichols LD, Czeisler CA. Use of transdermal melatonin delivery to improve sleep maintenance during daytime. Clin Pharmacol Ther. 2009 Oct; 86(4):378-82. PMID: 19606092; PMCID: PMC2909186.
    Citations: 18     Fields:    Translation:Humans
  148. Flynn-Evans EE, Stevens RG, Tabandeh H, Schernhammer ES, Lockley SW. Effect of light perception on menarche in blind women. Ophthalmic Epidemiol. 2009 Jul-Aug; 16(4):243-8. PMID: 19874146.
    Citations: 2     Fields:    Translation:Humans
  149. Cappuccio FP, Lockley SW, Landrigan CP. Cappuccio response to correspondence. QJM. 2009 May; 102(5):363-4. PMID: 19318371.
    Citations: 1     Fields:    Translation:Humans
  150. Barger LK, Lockley SW, Rajaratnam SM, Landrigan CP. Neurobehavioral, health, and safety consequences associated with shift work in safety-sensitive professions. Curr Neurol Neurosci Rep. 2009 Mar; 9(2):155-64. PMID: 19268039.
    Citations: 53     Fields:    Translation:Humans
  151. Anderson JL, Glod CA, Dai J, Cao Y, Lockley SW. Lux vs. wavelength in light treatment of Seasonal Affective Disorder. Acta Psychiatr Scand. 2009 Sep; 120(3):203-12. PMID: 19207131.
    Citations: 32     Fields:    Translation:Humans
  152. Cappuccio FP, Bakewell A, Taggart FM, Ward G, Ji C, Sullivan JP, Edmunds M, Pounder R, Landrigan CP, Lockley SW, Peile E. Implementing a 48 h EWTD-compliant rota for junior doctors in the UK does not compromise patients' safety: assessor-blind pilot comparison. QJM. 2009 Apr; 102(4):271-82. PMID: 19174502.
    Citations: 21     Fields:    Translation:Humans
  153. Lockley SW, Dijk DJ, Kosti O, Skene DJ, Arendt J. Alertness, mood and performance rhythm disturbances associated with circadian sleep disorders in the blind. J Sleep Res. 2008 Jun; 17(2):207-16. PMID: 18482109.
    Citations: 22     Fields:    Translation:Humans
  154. Zaidi FH, Hull JT, Peirson SN, Wulff K, Aeschbach D, Gooley JJ, Brainard GC, Gregory-Evans K, Rizzo JF, Czeisler CA, Foster RG, Moseley MJ, Lockley SW. Short-wavelength light sensitivity of circadian, pupillary, and visual awareness in humans lacking an outer retina. Curr Biol. 2007 Dec 18; 17(24):2122-8. PMID: 18082405.
    Citations: 109     Fields:    Translation:HumansCells
  155. Landrigan CP, Czeisler CA, Barger LK, Ayas NT, Rothschild JM, Lockley SW. Effective implementation of work-hour limits and systemic improvements. Jt Comm J Qual Patient Saf. 2007 Nov; 33(11 Suppl):19-29. PMID: 18173163.
    Citations: 14     Fields:    Translation:Humans
  156. Lockley SW, Barger LK, Ayas NT, Rothschild JM, Czeisler CA, Landrigan CP. Effects of health care provider work hours and sleep deprivation on safety and performance. Jt Comm J Qual Patient Saf. 2007 Nov; 33(11 Suppl):7-18. PMID: 18173162.
    Citations: 77     Fields:    Translation:Humans
  157. Zeitzer JM, Duffy JF, Lockley SW, Dijk DJ, Czeisler CA. Plasma melatonin rhythms in young and older humans during sleep, sleep deprivation, and wake. Sleep. 2007 Nov; 30(11):1437-43. PMID: 18041478.
    Citations: 26     Fields:    Translation:Humans
  158. Stevens RG, Blask DE, Brainard GC, Hansen J, Lockley SW, Provencio I, Rea MS, Reinlib L. Meeting report: the role of environmental lighting and circadian disruption in cancer and other diseases. Environ Health Perspect. 2007 Sep; 115(9):1357-62. PMID: 17805428; PMCID: PMC1964886.
    Citations: 83     Fields:    Translation:HumansAnimalsPHPublic Health
  159. Lockley SW. Safety considerations for the use of blue-light blocking glasses in shift-workers. J Pineal Res. 2007 Mar; 42(2):210-1. PMID: 17286754.
    Citations: 3     Fields:    Translation:Humans
  160. Lockley SW, Arendt J, Skene DJ. Visual impairment and circadian rhythm disorders. Dialogues Clin Neurosci. 2007; 9(3):301-14. PMID: 17969867.
    Citations: 39     Fields:    Translation:HumansAnimals
  161. Lockley SW, Gooley JJ. Circadian photoreception: spotlight on the brain. Curr Biol. 2006 Sep 19; 16(18):R795-7. PMID: 16979545.
    Citations: 19     Fields:    Translation:HumansCells
  162. Lockley SW, Landrigan CP, Barger LK, Czeisler CA. When policy meets physiology: the challenge of reducing resident work hours. Clin Orthop Relat Res. 2006 Aug; 449:116-27. PMID: 16770285.
    Citations: 23     Fields:    Translation:Humans
  163. Lockley SW, Evans EE, Scheer FA, Brainard GC, Czeisler CA, Aeschbach D. Short-wavelength sensitivity for the direct effects of light on alertness, vigilance, and the waking electroencephalogram in humans. Sleep. 2006 Feb; 29(2):161-8. PMID: 16494083.
    Citations: 166     Fields:    Translation:Humans
  164. Lockley SW. Timed melatonin treatment for delayed sleep phase syndrome: the importance of knowing circadian phase. Sleep. 2005 Oct; 28(10):1214-6. PMID: 16295202.
    Citations: 13     Fields:    Translation:Humans
  165. Rothschild JM, Landrigan CP, Cronin JW, Kaushal R, Lockley SW, Burdick E, Stone PH, Lilly CM, Katz JT, Czeisler CA, Bates DW. The Critical Care Safety Study: The incidence and nature of adverse events and serious medical errors in intensive care. Crit Care Med. 2005 Aug; 33(8):1694-700. PMID: 16096443.
    Citations: 174     Fields:    Translation:Humans
  166. Landrigan CP, Lockley SW, Czeisler CA. Effect of intern's consecutive work hours on safety, medical education and professionalism. Crit Care. 2005 Oct 05; 9(5):528-30; author reply 528-30. PMID: 16277743.
    Citations:    Fields:    Translation:Humans
  167. Lockley SW, Cronin JW, Evans EE, Cade BE, Lee CJ, Landrigan CP, Rothschild JM, Katz JT, Lilly CM, Stone PH, Aeschbach D, Czeisler CA. Effect of reducing interns' weekly work hours on sleep and attentional failures. N Engl J Med. 2004 Oct 28; 351(18):1829-37. PMID: 15509816.
    Citations: 195     Fields:    Translation:Humans
  168. Landrigan CP, Rothschild JM, Cronin JW, Kaushal R, Burdick E, Katz JT, Lilly CM, Stone PH, Lockley SW, Bates DW, Czeisler CA. Effect of reducing interns' work hours on serious medical errors in intensive care units. N Engl J Med. 2004 Oct 28; 351(18):1838-48. PMID: 15509817.
    Citations: 341     Fields:    Translation:HumansCTClinical Trials
  169. Hack LM, Lockley SW, Arendt J, Skene DJ. The effects of low-dose 0.5-mg melatonin on the free-running circadian rhythms of blind subjects. J Biol Rhythms. 2003 Oct; 18(5):420-9. PMID: 14582858.
    Citations: 34     Fields:    Translation:HumansCTClinical Trials
  170. Lockley SW, Brainard GC, Czeisler CA. High sensitivity of the human circadian melatonin rhythm to resetting by short wavelength light. J Clin Endocrinol Metab. 2003 Sep; 88(9):4502-5. PMID: 12970330.
    Citations: 194     Fields:    Translation:HumansCTClinical Trials
  171. Robilliard DL, Archer SN, Arendt J, Lockley SW, Hack LM, English J, Leger D, Smits MG, Williams A, Skene DJ, Von Schantz M. The 3111 Clock gene polymorphism is not associated with sleep and circadian rhythmicity in phenotypically characterized human subjects. J Sleep Res. 2002 Dec; 11(4):305-12. PMID: 12464098.
    Citations: 44     Fields:    Translation:Humans
  172. Dijk DJ, Lockley SW. Integration of human sleep-wake regulation and circadian rhythmicity. J Appl Physiol (1985). 2002 Feb; 92(2):852-62. PMID: 11796701.
    Citations: 66     Fields:    Translation:HumansCells
  173. Lockley SW, Skene DJ, James K, Thapan K, Wright J, Arendt J. Melatonin administration can entrain the free-running circadian system of blind subjects. J Endocrinol. 2000 Jan; 164(1):R1-6. PMID: 10607943.
    Citations: 63     Fields:    Translation:HumansCTClinical Trials
  174. Lockley SW, Skene DJ, Arendt J. Comparison between subjective and actigraphic measurement of sleep and sleep rhythms. J Sleep Res. 1999 Sep; 8(3):175-83. PMID: 10476003.
    Citations: 184     Fields:    Translation:Humans
  175. Lockley SW, Skene DJ, Butler LJ, Arendt J. Sleep and activity rhythms are related to circadian phase in the blind. Sleep. 1999 Aug 01; 22(5):616-23. PMID: 10450596.
    Citations: 21     Fields:    Translation:Humans
  176. Skene DJ, Lockley SW, James K, Arendt J. Correlation between urinary cortisol and 6-sulphatoxymelatonin rhythms in field studies of blind subjects. Clin Endocrinol (Oxf). 1999 Jun; 50(6):715-9. PMID: 10468942.
    Citations: 16     Fields:    Translation:Humans
  177. Skene DJ, Lockley SW, Thapan K, Arendt J. Effects of light on human circadian rhythms. Reprod Nutr Dev. 1999 May-Jun; 39(3):295-304. PMID: 10420432.
    Citations: 16     Fields:    Translation:Humans
  178. Skene DJ, Lockley SW, Arendt J. Melatonin in circadian sleep disorders in the blind. Biol Signals Recept. 1999 Jan-Apr; 8(1-2):90-5. PMID: 10085469.
    Citations: 9     Fields:    Translation:Humans
  179. Skene DJ, Lockley SW, Arendt J. Use of melatonin in the treatment of phase shift and sleep disorders. Adv Exp Med Biol. 1999; 467:79-84. PMID: 10721041.
    Citations: 11     Fields:    Translation:Humans
  180. Tabandeh H, Lockley SW, Buttery R, Skene DJ, Defrance R, Arendt J, Bird AC. Disturbance of sleep in blindness. Am J Ophthalmol. 1998 Nov; 126(5):707-12. PMID: 9822235.
    Citations: 24     Fields:    Translation:Humans
  181. Lockley SW, Skene DJ, Thapan K, English J, Ribeiro D, Haimov I, Hampton S, Middleton B, von Schantz M, Arendt J. Extraocular light exposure does not suppress plasma melatonin in humans. J Clin Endocrinol Metab. 1998 Sep; 83(9):3369-72. PMID: 9745457.
    Citations: 15     Fields:    Translation:HumansCells
  182. Arendt J, Skene DJ, Middleton B, Lockley SW, Deacon S. Efficacy of melatonin treatment in jet lag, shift work, and blindness. J Biol Rhythms. 1997 Dec; 12(6):604-17. PMID: 9406036.
    Citations: 31     Fields:    Translation:HumansAnimals
  183. Lockley SW, Skene DJ, Arendt J, Tabandeh H, Bird AC, Defrance R. Relationship between melatonin rhythms and visual loss in the blind. J Clin Endocrinol Metab. 1997 Nov; 82(11):3763-70. PMID: 9360538.
    Citations: 67     Fields:    Translation:Humans
  184. Lockley SW, Skene DJ, Tabandeh H, Bird AC, Defrance R, Arendt J. Relationship between napping and melatonin in the blind. J Biol Rhythms. 1997 Feb; 12(1):16-25. PMID: 9104687.
    Citations: 23     Fields:    Translation:HumansCTClinical Trials
  185. Lockley S, Tabandeh H, Skene D, Buttery R, Bird A, Defrace R, Arendt J. Day-time naps and melatonin in blind people. Lancet. 1995 Dec 02; 346(8988):1491. PMID: 7491012.
    Citations: 5     Fields:    Translation:Humans
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