Harvard Catalyst Profiles

Contact, publication, and social network information about Harvard faculty and fellows.

Mark Daniel Fleming, M.D., D.Phil.

Co-Author

This page shows the publications co-authored by Mark Fleming and Dean Campagna.
Connection Strength

4.626
  1. X-linked sideroblastic anemia due to ALAS2 intron 1 enhancer element GATA-binding site mutations. Am J Hematol. 2014 Mar; 89(3):315-9.
    View in: PubMed
    Score: 0.578
  2. Mutations in the serum/glucocorticoid regulated kinase 3 (Sgk3) are responsible for the mouse fuzzy (fz) hair phenotype. J Invest Dermatol. 2008 Mar; 128(3):730-2.
    View in: PubMed
    Score: 0.378
  3. A synonymous coding variant that alters ALAS2 splicing and causes X-linked sideroblastic anemia. Pediatr Blood Cancer. 2021 Aug 19; e29309.
    View in: PubMed
    Score: 0.247
  4. SLC25A38 congenital sideroblastic anemia: Phenotypes and genotypes of 31 individuals from 24 families, including 11 novel mutations, and a review of the literature. Hum Mutat. 2021 Nov; 42(11):1367-1383.
    View in: PubMed
    Score: 0.247
  5. The phenotypic spectrum of germline YARS2 variants: from isolated sideroblastic anemia to mitochondrial myopathy, lactic acidosis and sideroblastic anemia 2. Haematologica. 2018 12; 103(12):2008-2015.
    View in: PubMed
    Score: 0.200
  6. Recurrent heteroplasmy for the MT-ATP6 p.Ser148Asn (m.8969G>A) mutation in patients with syndromic congenital sideroblastic anemia of variable clinical severity. Haematologica. 2018 12; 103(12):e561-e563.
    View in: PubMed
    Score: 0.199
  7. Normalizing hepcidin predicts TMPRSS6 mutation status in patients with chronic iron deficiency. Blood. 2018 07 26; 132(4):448-452.
    View in: PubMed
    Score: 0.198
  8. A recurring mutation in the respiratory complex 1 protein NDUFB11 is responsible for a novel form of X-linked sideroblastic anemia. Blood. 2016 10 13; 128(15):1913-1917.
    View in: PubMed
    Score: 0.174
  9. Congenital sideroblastic anemia due to mutations in the mitochondrial HSP70 homologue HSPA9. Blood. 2015 Dec 17; 126(25):2734-8.
    View in: PubMed
    Score: 0.165
  10. Mutations in TRNT1 cause congenital sideroblastic anemia with immunodeficiency, fevers, and developmental delay (SIFD). Blood. 2014 Oct 30; 124(18):2867-71.
    View in: PubMed
    Score: 0.153
  11. Identification and characterization of a novel murine allele of Tmprss6. Haematologica. 2013 Jun; 98(6):854-61.
    View in: PubMed
    Score: 0.136
  12. QTLs for murine red blood cell parameters in LG/J and SM/J F(2) and advanced intercross lines. Mamm Genome. 2012 Jun; 23(5-6):356-66.
    View in: PubMed
    Score: 0.128
  13. Characterization of mitochondrial ferritin-deficient mice. Am J Hematol. 2010 Dec; 85(12):958-60.
    View in: PubMed
    Score: 0.118
  14. Cdk5rap2 regulates centrosome function and chromosome segregation in neuronal progenitors. Development. 2010 Jun; 137(11):1907-17.
    View in: PubMed
    Score: 0.114
  15. hem6: an ENU-induced recessive hypochromic microcytic anemia mutation in the mouse. Blood. 2008 Nov 15; 112(10):4308-13.
    View in: PubMed
    Score: 0.101
  16. Mutations in TMPRSS6 cause iron-refractory iron deficiency anemia (IRIDA). Nat Genet. 2008 May; 40(5):569-71.
    View in: PubMed
    Score: 0.098
  17. Primary ciliary dyskinesia in mice lacking the novel ciliary protein Pcdp1. Mol Cell Biol. 2008 Feb; 28(3):949-57.
    View in: PubMed
    Score: 0.095
  18. X-linked gray platelet syndrome due to a GATA1 Arg216Gln mutation. Blood. 2007 Apr 15; 109(8):3297-9.
    View in: PubMed
    Score: 0.090
  19. Abcb7, the gene responsible for X-linked sideroblastic anemia with ataxia, is essential for hematopoiesis. Blood. 2007 Apr 15; 109(8):3567-9.
    View in: PubMed
    Score: 0.090
  20. Loss of the acyl-CoA binding protein (Acbp) results in fatty acid metabolism abnormalities in mouse hair and skin. J Invest Dermatol. 2007 Jan; 127(1):16-23.
    View in: PubMed
    Score: 0.087
  21. The Steap proteins are metalloreductases. Blood. 2006 Aug 15; 108(4):1388-94.
    View in: PubMed
    Score: 0.085
  22. The mitochondrial ATP-binding cassette transporter Abcb7 is essential in mice and participates in cytosolic iron-sulfur cluster biogenesis. Hum Mol Genet. 2006 Mar 15; 15(6):953-64.
    View in: PubMed
    Score: 0.084
  23. Identification of a ferrireductase required for efficient transferrin-dependent iron uptake in erythroid cells. Nat Genet. 2005 Nov; 37(11):1264-9.
    View in: PubMed
    Score: 0.082
  24. nm1054: a spontaneous, recessive, hypochromic, microcytic anemia mutation in the mouse. Blood. 2005 Nov 15; 106(10):3625-31.
    View in: PubMed
    Score: 0.081
  25. Hepcidin-Mediated Hypoferremia Disrupts Immune Responses to Vaccination and Infection. Med (N Y). 2021 Feb 12; 2(2):164-179.e12.
    View in: PubMed
    Score: 0.060
  26. Mutations in the iron-sulfur cluster biogenesis protein HSCB cause congenital sideroblastic anemia. J Clin Invest. 2020 10 01; 130(10):5245-5256.
    View in: PubMed
    Score: 0.058
  27. A Murine Model of Chronic Lymphocytic Leukemia Based on B Cell-Restricted Expression of Sf3b1 Mutation and Atm Deletion. Cancer Cell. 2019 02 11; 35(2):283-296.e5.
    View in: PubMed
    Score: 0.052
  28. Pancreatic lipomatosis in Diamond-Blackfan anemia: The importance of genetic testing in bone marrow failure disorders. Am J Hematol. 2018 09; 93(9):1194-1195.
    View in: PubMed
    Score: 0.050
  29. Congenital macrothrombocytopenia with focal myelofibrosis due to mutations in human G6b-B is rescued in humanized mice. Blood. 2018 09 27; 132(13):1399-1412.
    View in: PubMed
    Score: 0.050
  30. UBE2O remodels the proteome during terminal erythroid differentiation. Science. 2017 08 04; 357(6350).
    View in: PubMed
    Score: 0.047
  31. Ringed sideroblasts in ß-thalassemia. Pediatr Blood Cancer. 2017 05; 64(5).
    View in: PubMed
    Score: 0.044
  32. Physiologic Expression of Sf3b1(K700E) Causes Impaired Erythropoiesis, Aberrant Splicing, and Sensitivity to Therapeutic Spliceosome Modulation. Cancer Cell. 2016 09 12; 30(3):404-417.
    View in: PubMed
    Score: 0.044
  33. Pseudouridine synthase 1 deficient mice, a model for Mitochondrial Myopathy with Sideroblastic Anemia, exhibit muscle morphology and physiology alterations. Sci Rep. 2016 05 20; 6:26202.
    View in: PubMed
    Score: 0.043
  34. LARS2 Variants Associated with Hydrops, Lactic Acidosis, Sideroblastic Anemia, and Multisystem Failure. JIMD Rep. 2016; 28:49-57.
    View in: PubMed
    Score: 0.041
  35. Screen for alterations of iron related parameters in N-ethyl-N-nitrosourea-treated mice identified mutant lines with increased plasma ferritin levels. Biometals. 2015 Apr; 28(2):293-306.
    View in: PubMed
    Score: 0.039
  36. HRG1 is essential for heme transport from the phagolysosome of macrophages during erythrophagocytosis. Cell Metab. 2013 Feb 05; 17(2):261-70.
    View in: PubMed
    Score: 0.034
  37. Mitochondrial Atpif1 regulates haem synthesis in developing erythroblasts. Nature. 2012 Nov 22; 491(7425):608-12.
    View in: PubMed
    Score: 0.034
  38. Systematic molecular genetic analysis of congenital sideroblastic anemia: evidence for genetic heterogeneity and identification of novel mutations. Pediatr Blood Cancer. 2010 Feb; 54(2):273-8.
    View in: PubMed
    Score: 0.028
  39. Mutations in mitochondrial carrier family gene SLC25A38 cause nonsyndromic autosomal recessive congenital sideroblastic anemia. Nat Genet. 2009 Jun; 41(6):651-3.
    View in: PubMed
    Score: 0.026
  40. Identification of a Steap3 endosomal targeting motif essential for normal iron metabolism. Blood. 2009 Feb 19; 113(8):1805-8.
    View in: PubMed
    Score: 0.025
  41. Genetic variation in Mon1a affects protein trafficking and modifies macrophage iron loading in mice. Nat Genet. 2007 Aug; 39(8):1025-32.
    View in: PubMed
    Score: 0.023
Connection Strength
The connection strength for co-authors is the sum of the scores for each of their shared publications.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.
Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.