Harvard Catalyst Profiles

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Simon Jenni, Ph.D.


Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Jenni S, Horwitz JA, Bloyet LM, Whelan SPJ, Harrison SC. Visualizing molecular interactions that determine assembly of a bullet-shaped vesicular stomatitis virus particle. Nat Commun. 2022 08 15; 13(1):4802. PMID: 35970826; PMCID: PMC9378655.
    Citations: 1     Fields:    Translation:AnimalsCells
  2. Jenni S, Li Z, Wang Y, Bessey T, Salgado EN, Schmidt AG, Greenberg HB, Jiang B, Harrison SC. Rotavirus VP4 Epitope of a Broadly Neutralizing Human Antibody Defined by Its Structure Bound with an Attenuated-Strain Virion. J Virol. 2022 08 24; 96(16):e0062722. PMID: 35924923; PMCID: PMC9400500.
    Citations:    Fields:    Translation:HumansAnimalsCells
  3. Tong P, Gautam A, Windsor IW, Travers M, Chen Y, Garcia N, Whiteman NB, McKay LGA, Storm N, Malsick LE, Honko AN, Lelis FJN, Habibi S, Jenni S, Cai Y, Rennick LJ, Duprex WP, McCarthy KR, Lavine CL, Zuo T, Lin J, Zuiani A, Feldman J, MacDonald EA, Hauser BM, Griffths A, Seaman MS, Schmidt AG, Chen B, Neuberg D, Bajic G, Harrison SC, Wesemann DR. Memory B cell repertoire for recognition of evolving SARS-CoV-2 spike. Cell. 2021 09 16; 184(19):4969-4980.e15. PMID: 34332650; PMCID: PMC8299219.
    Citations: 31     Fields:    
  4. Herrmann T, Torres R, Salgado EN, Berciu C, Stoddard D, Nicastro D, Jenni S, Harrison SC. Functional refolding of the penetration protein on a non-enveloped virus. Nature. 2021 02; 590(7847):666-670. PMID: 33442061; PMCID: PMC8297411.
    Citations: 9     Fields:    Translation:AnimalsCells
  5. McCarthy KR, Timpona JL, Jenni S, Bloyet LM, Brusic V, Johnson WE, Whelan SPJ, Robinson-McCarthy LR. Structure of the Receptor Binding Domain of EnvP(b)1, an Endogenous Retroviral Envelope Protein Expressed in Human Tissues. mBio. 2020 11 17; 11(6). PMID: 33203760.
    Citations: 2     Fields:    Translation:HumansAnimalsCells
  6. Fei X, Bell TA, Jenni S, Stinson BM, Baker TA, Harrison SC, Sauer RT. Structures of the ATP-fueled ClpXP proteolytic machine bound to protein substrate. Elife. 2020 02 28; 9. PMID: 32108573.
    Citations: 33     Fields:    Translation:Cells
  7. Horwitz JA, Jenni S, Harrison SC, Whelan SPJ. Structure of a rabies virus polymerase complex from electron cryo-microscopy. Proc Natl Acad Sci U S A. 2020 01 28; 117(4):2099-2107. PMID: 31953264; PMCID: PMC6995008.
    Citations: 21     Fields:    Translation:HumansCells
  8. Jenni S, Bloyet LM, Diaz-Avalos R, Liang B, Whelan SPJ, Grigorieff N, Harrison SC. Structure of the Vesicular Stomatitis Virus L Protein in Complex with Its Phosphoprotein Cofactor. Cell Rep. 2020 01 07; 30(1):53-60.e5. PMID: 31914397.
    Citations: 26     Fields:    Translation:HumansAnimalsCells
  9. Jenni S, Salgado EN, Herrmann T, Li Z, Grant T, Grigorieff N, Trapani S, Estrozi LF, Harrison SC. In situ Structure of Rotavirus VP1 RNA-Dependent RNA Polymerase. J Mol Biol. 2019 08 09; 431(17):3124-3138. PMID: 31233764; PMCID: PMC6697194.
    Citations: 14     Fields:    Translation:Cells
  10. Jenni S, Harrison SC. Structure of the DASH/Dam1 complex shows its role at the yeast kinetochore-microtubule interface. Science. 2018 05 04; 360(6388):552-558. PMID: 29724956; PMCID: PMC6815591.
    Citations: 26     Fields:    Translation:AnimalsCells
  11. Jenni S, Dimitrova YN, Valverde R, Hinshaw SM, Harrison SC. Molecular Structures of Yeast Kinetochore Subcomplexes and Their Roles in Chromosome Segregation. Cold Spring Harb Symp Quant Biol. 2017; 82:83-89. PMID: 29167284.
    Citations: 3     Fields:    
  12. Liu Y, Pan J, Jenni S, Raymond DD, Caradonna T, Do KT, Schmidt AG, Harrison SC, Grigorieff N. CryoEM Structure of an Influenza Virus Receptor-Binding Site Antibody-Antigen Interface. J Mol Biol. 2017 06 16; 429(12):1829-1839. PMID: 28506635; PMCID: PMC5535819.
    Citations: 12     Fields:    Translation:Cells
  13. Kim IS, Jenni S, Stanifer ML, Roth E, Whelan SP, van Oijen AM, Harrison SC. Mechanism of membrane fusion induced by vesicular stomatitis virus G protein. Proc Natl Acad Sci U S A. 2017 01 03; 114(1):E28-E36. PMID: 27974607; PMCID: PMC5224367.
    Citations: 45     Fields:    Translation:AnimalsCells
  14. Petrovic A, Keller J, Liu Y, Overlack K, John J, Dimitrova YN, Jenni S, van Gerwen S, Stege P, Wohlgemuth S, Rombaut P, Herzog F, Harrison SC, Vetter IR, Musacchio A. Structure of the MIS12 Complex and Molecular Basis of Its Interaction with CENP-C at Human Kinetochores. Cell. 2016 11 03; 167(4):1028-1040.e15. PMID: 27881301.
    Citations: 55     Fields:    Translation:HumansAnimalsCells
  15. Dimitrova YN, Jenni S, Valverde R, Khin Y, Harrison SC. Structure of the MIND Complex Defines a Regulatory Focus for Yeast Kinetochore Assembly. Cell. 2016 11 03; 167(4):1014-1027.e12. PMID: 27881300; PMCID: PMC5856483.
    Citations: 48     Fields:    Translation:AnimalsCells
  16. Jenni S, Goyal Y, von Grotthuss M, Shvartsman SY, Klein DE. Structural Basis of Neurohormone Perception by the Receptor Tyrosine Kinase Torso. Mol Cell. 2015 Dec 17; 60(6):941-52. PMID: 26698662.
    Citations: 7     Fields:    Translation:HumansAnimalsCells
  17. Liang B, Li Z, Jenni S, Rahmeh AA, Morin BM, Grant T, Grigorieff N, Harrison SC, Whelan SPJ. Structure of the L Protein of Vesicular Stomatitis Virus from Electron Cryomicroscopy. Cell. 2015 Jul 16; 162(2):314-327. PMID: 26144317.
    Citations: 132     Fields:    Translation:Cells
  18. Papadopoulos E, Jenni S, Kabha E, Takrouri KJ, Yi T, Salvi N, Luna RE, Gavathiotis E, Mahalingam P, Arthanari H, Rodriguez-Mias R, Yefidoff-Freedman R, Aktas BH, Chorev M, Halperin JA, Wagner G. Structure of the eukaryotic translation initiation factor eIF4E in complex with 4EGI-1 reveals an allosteric mechanism for dissociating eIF4G. Proc Natl Acad Sci U S A. 2014 Aug 05; 111(31):E3187-95. PMID: 25049413.
    Citations: 36     Fields:    Translation:HumansCells
  19. Ford MG, Jenni S, Nunnari J. The crystal structure of dynamin. Nature. 2011 Sep 18; 477(7366):561-6. PMID: 21927001.
    Citations: 126     Fields:    Translation:HumansAnimalsCells
  20. Jenni S, Ban N. Imperfect pseudo-merohedral twinning in crystals of fungal fatty acid synthase. Acta Crystallogr D Biol Crystallogr. 2009 Feb; 65(Pt 2):101-11. PMID: 19171964.
    Citations: 8     Fields:    Translation:Cells
  21. Leibundgut M, Maier T, Jenni S, Ban N. The multienzyme architecture of eukaryotic fatty acid synthases. Curr Opin Struct Biol. 2008 Dec; 18(6):714-25. PMID: 18948193.
    Citations: 54     Fields:    Translation:AnimalsCells
  22. Mueller M, Jenni S, Ban N. Strategies for crystallization and structure determination of very large macromolecular assemblies. Curr Opin Struct Biol. 2007 Oct; 17(5):572-9. PMID: 17964135.
    Citations: 16     Fields:    Translation:Cells
  23. Jenni S, Leibundgut M, Boehringer D, Frick C, Mikolásek B, Ban N. Structure of fungal fatty acid synthase and implications for iterative substrate shuttling. Science. 2007 Apr 13; 316(5822):254-61. PMID: 17431175.
    Citations: 74     Fields:    Translation:AnimalsCells
  24. Leibundgut M, Jenni S, Frick C, Ban N. Structural basis for substrate delivery by acyl carrier protein in the yeast fatty acid synthase. Science. 2007 Apr 13; 316(5822):288-90. PMID: 17431182.
    Citations: 74     Fields:    Translation:Cells
  25. Jenni S, Leibundgut M, Maier T, Ban N. Architecture of a fungal fatty acid synthase at 5 A resolution. Science. 2006 Mar 03; 311(5765):1263-7. PMID: 16513976.
    Citations: 42     Fields:    Translation:AnimalsCells
  26. Maier T, Jenni S, Ban N. Architecture of mammalian fatty acid synthase at 4.5 A resolution. Science. 2006 Mar 03; 311(5765):1258-62. PMID: 16513975.
    Citations: 116     Fields:    Translation:AnimalsCells
  27. Mitra K, Schaffitzel C, Shaikh T, Tama F, Jenni S, Brooks CL, Ban N, Frank J. Structure of the E. coli protein-conducting channel bound to a translating ribosome. Nature. 2005 Nov 17; 438(7066):318-24. PMID: 16292303.
    Citations: 91     Fields:    Translation:Cells
  28. Pfister P, Jenni S, Poehlsgaard J, Thomas A, Douthwaite S, Ban N, Böttger EC. The structural basis of macrolide-ribosome binding assessed using mutagenesis of 23S rRNA positions 2058 and 2059. J Mol Biol. 2004 Oct 01; 342(5):1569-81. PMID: 15364582.
    Citations: 27     Fields:    Translation:Cells
  29. Jenni S, Ban N. The chemistry of protein synthesis and voyage through the ribosomal tunnel. Curr Opin Struct Biol. 2003 Apr; 13(2):212-9. PMID: 12727515.
    Citations: 20     Fields:    Translation:Cells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.