Harvard Catalyst Profiles

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Johannes Walter, Ph.D.


The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. R01HL098316 (WALTER, JOHANNES) Feb 1, 2010 - Mar 31, 2024
    Mechanisms of DNA interstrand cross-link repair
    Role: Principal Investigator
  2. R01GM080676 (WALTER, JOHANNES) Sep 20, 2007 - Mar 31, 2021
    The mechanism of vertebrate DNA replication termination
    Role: Principal Investigator
  3. R01GM062267 (WALTER, JOHANNES) Jul 1, 2001 - Jun 30, 2015
    Mechanism of the eukaryotic replicative DNA helicase
    Role: Principal Investigator
  4. F32GM017980 (WALTER, JOHANNES) Mar 14, 1996
    Role: Principal Investigator

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Mevissen TET, Prasad AV, Walter JC. TRIM21-dependent target protein ubiquitination mediates cell-free Trim-Away. Cell Rep. 2023 Feb 18; 42(2):112125. PMID: 36807144.
    Citations:    Fields:    
  2. Kochenova OV, Mukkavalli S, Raman M, Walter JC. Cooperative assembly of p97 complexes involved in replication termination. Nat Commun. 2022 11 03; 13(1):6591. PMID: 36329031; PMCID: PMC9633789.
    Citations: 2     Fields:    Translation:Cells
  3. Suski JM, Ratnayeke N, Braun M, Zhang T, Strmiska V, Michowski W, Can G, Simoneau A, Snioch K, Cup M, Sullivan CM, Wu X, Nowacka J, Branigan TB, Pack LR, DeCaprio JA, Geng Y, Zou L, Gygi SP, Walter JC, Meyer T, Sicinski P. CDC7-independent G1/S transition revealed by targeted protein degradation. Nature. 2022 05; 605(7909):357-365. PMID: 35508654; PMCID: PMC9106935.
    Citations: 2     Fields:    Translation:AnimalsCells
  4. Zhou H, Zaher MS, Walter JC, Brown A. Structure of CRL2Lrr1, the E3 ubiquitin ligase that promotes DNA replication termination in vertebrates. Nucleic Acids Res. 2021 12 16; 49(22):13194-13206. PMID: 34850944; PMCID: PMC8682755.
    Citations:    Fields:    Translation:AnimalsCells
  5. Semlow DR, Walter JC. Mechanisms of Vertebrate DNA Interstrand Cross-Link Repair. Annu Rev Biochem. 2021 06 20; 90:107-135. PMID: 33882259.
    Citations: 10     Fields:    Translation:HumansAnimalsCells
  6. Vrtis KB, Dewar JM, Chistol G, Wu RA, Graham TGW, Walter JC. Single-strand DNA breaks cause replisome disassembly. Mol Cell. 2021 03 18; 81(6):1309-1318.e6. PMID: 33484638; PMCID: PMC7979477.
    Citations: 21     Fields:    Translation:AnimalsCells
  7. Wu RA, Pellman DS, Walter JC. The Ubiquitin Ligase TRAIP: Double-Edged Sword at the Replisome. Trends Cell Biol. 2021 02; 31(2):75-85. PMID: 33317933; PMCID: PMC7856240.
    Citations: 7     Fields:    Translation:HumansAnimalsCells
  8. Low E, Chistol G, Zaher MS, Kochenova OV, Walter JC. The DNA replication fork suppresses CMG unloading from chromatin before termination. Genes Dev. 2020 11 01; 34(21-22):1534-1545. PMID: 32943574.
    Citations: 11     Fields:    Translation:AnimalsCells
  9. Amunugama R, Walter JC. A new varietal of DNA interstrand crosslink repair. Cell Res. 2020 06; 30(6):459-460. PMID: 32346072.
    Citations: 1     Fields:    Translation:Cells
  10. Stinson BM, Moreno AT, Walter JC, Loparo JJ. A Mechanism to Minimize Errors during Non-homologous End Joining. Mol Cell. 2020 03 05; 77(5):1080-1091.e8. PMID: 31862156.
    Citations: 26     Fields:    Translation:AnimalsCells
  11. Deng L, Wu RA, Sonneville R, Kochenova OV, Labib K, Pellman D, Walter JC. Mitotic CDK Promotes Replisome Disassembly, Fork Breakage, and Complex DNA Rearrangements. Mol Cell. 2019 03 07; 73(5):915-929.e6. PMID: 30849395; PMCID: PMC6410736.
    Citations: 50     Fields:    Translation:AnimalsCells
  12. Wu RA, Semlow DR, Kamimae-Lanning AN, Kochenova OV, Chistol G, Hodskinson MR, Amunugama R, Sparks JL, Wang M, Deng L, Mimoso CA, Low E, Patel KJ, Walter JC. TRAIP is a master regulator of DNA interstrand crosslink repair. Nature. 2019 03; 567(7747):267-272. PMID: 30842657.
    Citations: 62     Fields:    Translation:HumansAnimalsCells
  13. Sparks J, Walter JC. Extracts for Analysis of DNA Replication in a Nucleus-Free System. Cold Spring Harb Protoc. 2019 03 01; 2019(3). PMID: 29769389.
    Citations: 9     Fields:    Translation:AnimalsCells
  14. Sparks JL, Chistol G, Gao AO, Räschle M, Larsen NB, Mann M, Duxin JP, Walter JC. The CMG Helicase Bypasses DNA-Protein Cross-Links to Facilitate Their Repair. Cell. 2019 01 10; 176(1-2):167-181.e21. PMID: 30595447; PMCID: PMC6475077.
    Citations: 66     Fields:    Translation:AnimalsCells
  15. Graham TGW, Carney SM, Walter JC, Loparo JJ. A single XLF dimer bridges DNA ends during nonhomologous end joining. Nat Struct Mol Biol. 2018 09; 25(9):877-884. PMID: 30177755; PMCID: PMC6128732.
    Citations: 23     Fields:    Translation:HumansAnimalsCells
  16. Amunugama R, Willcox S, Wu RA, Abdullah UB, El-Sagheer AH, Brown T, McHugh PJ, Griffith JD, Walter JC. Replication Fork Reversal during DNA Interstrand Crosslink Repair Requires CMG Unloading. Cell Rep. 2018 06 19; 23(12):3419-3428. PMID: 29924986; PMCID: PMC6086610.
    Citations: 37     Fields:    Translation:AnimalsCells
  17. Graham TGW, Walter JC, Loparo JJ. Ensemble and Single-Molecule Analysis of Non-Homologous End Joining in Frog Egg Extracts. Methods Enzymol. 2017; 591:233-270. PMID: 28645371; PMCID: PMC6404771.
    Citations: 8     Fields:    Translation:AnimalsCells
  18. Dewar JM, Low E, Mann M, Räschle M, Walter JC. CRL2Lrr1 promotes unloading of the vertebrate replisome from chromatin during replication termination. Genes Dev. 2017 02 01; 31(3):275-290. PMID: 28235849; PMCID: PMC5358724.
    Citations: 44     Fields:    Translation:AnimalsCells
  19. Semlow DR, Zhang J, Budzowska M, Drohat AC, Walter JC. Replication-Dependent Unhooking of DNA Interstrand Cross-Links by the NEIL3 Glycosylase. Cell. 2016 Oct 06; 167(2):498-511.e14. PMID: 27693351.
    Citations: 87     Fields:    Translation:AnimalsCells
  20. Graham TG, Walter JC, Loparo JJ. Two-Stage Synapsis of DNA Ends during Non-homologous End Joining. Mol Cell. 2016 Mar 17; 61(6):850-8. PMID: 26990988; PMCID: PMC4799494.
    Citations: 62     Fields:    Translation:HumansCells
  21. Joukov V, Walter JC, De Nicolo A. Assays to Study Mitotic Centrosome and Spindle Pole Assembly and Regulation. Methods Mol Biol. 2016; 1413:207-35. PMID: 27193852.
    Citations:    Fields:    Translation:AnimalsCells
  22. Duxin JP, Walter JC. What is the DNA repair defect underlying Fanconi anemia? Curr Opin Cell Biol. 2015 Dec; 37:49-60. PMID: 26512453; PMCID: PMC4688103.
    Citations: 78     Fields:    Translation:HumansAnimalsCells
  23. Dewar JM, Budzowska M, Walter JC. The mechanism of DNA replication termination in vertebrates. Nature. 2015 Sep 17; 525(7569):345-50. PMID: 26322582.
    Citations: 65     Fields:    Translation:AnimalsCells
  24. Budzowska M, Graham TG, Sobeck A, Waga S, Walter JC. Regulation of the Rev1-pol ? complex during bypass of a DNA interstrand cross-link. EMBO J. 2015 Jul 14; 34(14):1971-85. PMID: 26071591; PMCID: PMC4547899.
    Citations: 65     Fields:    Translation:AnimalsCells
  25. Chistol G, Walter JC. Single-Molecule Visualization of MCM2-7 DNA Loading: Seeing Is Believing. Cell. 2015 Apr 23; 161(3):429-430. PMID: 25910200.
    Citations: 4     Fields:    Translation:AnimalsCells
  26. Zhang J, Dewar JM, Budzowska M, Motnenko A, Cohn MA, Walter JC. DNA interstrand cross-link repair requires replication-fork convergence. Nat Struct Mol Biol. 2015 Mar; 22(3):242-7. PMID: 25643322; PMCID: PMC4351167.
    Citations: 77     Fields:    Translation:AnimalsCells
  27. Duxin JP, Dewar JM, Yardimci H, Walter JC. Repair of a DNA-protein crosslink by replication-coupled proteolysis. Cell. 2014 Oct 09; 159(2):346-57. PMID: 25303529.
    Citations: 105     Fields:    Translation:AnimalsCells
  28. Long DT, Joukov V, Budzowska M, Walter JC. BRCA1 promotes unloading of the CMG helicase from a stalled DNA replication fork. Mol Cell. 2014 Oct 02; 56(1):174-85. PMID: 25219499.
    Citations: 65     Fields:    Translation:AnimalsCells
  29. Joukov V, Walter JC, De Nicolo A. The Cep192-organized aurora A-Plk1 cascade is essential for centrosome cycle and bipolar spindle assembly. Mol Cell. 2014 Aug 21; 55(4):578-91. PMID: 25042804; PMCID: PMC4245277.
    Citations: 79     Fields:    Translation:HumansAnimalsCells
  30. Slenn TJ, Morris B, Havens CG, Freeman RM, Takahashi TS, Walter JC. Thymine DNA glycosylase is a CRL4Cdt2 substrate. J Biol Chem. 2014 Aug 15; 289(33):23043-23055. PMID: 24947512.
    Citations: 28     Fields:    Translation:AnimalsCells
  31. Chistol G, Walter J. Molecular watchdogs on genome patrol. Elife. 2014 Apr 29; 3:e02854. PMID: 24843031; PMCID: PMC3999853.
    Citations: 3     Fields:    Translation:Animals
  32. Zhang J, Walter JC. Mechanism and regulation of incisions during DNA interstrand cross-link repair. DNA Repair (Amst). 2014 Jul; 19:135-42. PMID: 24768452.
    Citations: 109     Fields:    Translation:HumansCells
  33. Yardimci H, Walter JC. Prereplication-complex formation: a molecular double take? Nat Struct Mol Biol. 2014 Jan; 21(1):20-5. PMID: 24389553.
    Citations: 36     Fields:    
  34. Dewar JM, Walter JC. Chromosome biology: conflict management for replication and transcription. Curr Biol. 2013 Mar 04; 23(5):R200-2. PMID: 23473562.
    Citations: 2     Fields:    Translation:AnimalsCells
  35. Yardimci H, Wang X, Loveland AB, Tappin I, Rudner DZ, Hurwitz J, van Oijen AM, Walter JC. Bypass of a protein barrier by a replicative DNA helicase. Nature. 2012 Dec 13; 492(7428):205-9. PMID: 23201686.
    Citations: 53     Fields:    Translation:Cells
  36. Loveland AB, Habuchi S, Walter JC, van Oijen AM. A general approach to break the concentration barrier in single-molecule imaging. Nat Methods. 2012 Oct; 9(10):987-92. PMID: 22961247.
    Citations: 33     Fields:    Translation:Cells
  37. Long DT, Walter JC. A novel function for BRCA1 in crosslink repair. Mol Cell. 2012 Apr 27; 46(2):111-2. PMID: 22541552.
    Citations: 6     Fields:    
  38. Yardimci H, Loveland AB, van Oijen AM, Walter JC. Single-molecule analysis of DNA replication in Xenopus egg extracts. Methods. 2012 Jun; 57(2):179-86. PMID: 22503776.
    Citations: 30     Fields:    Translation:AnimalsCells
  39. Havens CG, Shobnam N, Guarino E, Centore RC, Zou L, Kearsey SE, Walter JC. Direct role for proliferating cell nuclear antigen in substrate recognition by the E3 ubiquitin ligase CRL4Cdt2. J Biol Chem. 2012 Mar 30; 287(14):11410-21. PMID: 22303007.
    Citations: 26     Fields:    Translation:HumansAnimalsCells
  40. Raman M, Havens CG, Walter JC, Harper JW. A genome-wide screen identifies p97 as an essential regulator of DNA damage-dependent CDT1 destruction. Mol Cell. 2011 Oct 07; 44(1):72-84. PMID: 21981919.
    Citations: 65     Fields:    Translation:HumansAnimalsCells
  41. Fu YV, Yardimci H, Long DT, Ho TV, Guainazzi A, Bermudez VP, Hurwitz J, van Oijen A, Schärer OD, Walter JC. Selective bypass of a lagging strand roadblock by the eukaryotic replicative DNA helicase. Cell. 2011 Sep 16; 146(6):931-41. PMID: 21925316.
    Citations: 208     Fields:    Translation:AnimalsCells
  42. Havens CG, Walter JC. Mechanism of CRL4(Cdt2), a PCNA-dependent E3 ubiquitin ligase. Genes Dev. 2011 Aug 01; 25(15):1568-82. PMID: 21828267.
    Citations: 121     Fields:    Translation:HumansAnimalsCells
  43. Long DT, Räschle M, Joukov V, Walter JC. Mechanism of RAD51-dependent DNA interstrand cross-link repair. Science. 2011 Jul 01; 333(6038):84-7. PMID: 21719678.
    Citations: 136     Fields:    Translation:AnimalsCells
  44. Yardimci H, Loveland AB, Habuchi S, van Oijen AM, Walter JC. Uncoupling of sister replisomes during eukaryotic DNA replication. Mol Cell. 2010 Dec 10; 40(5):834-40. PMID: 21145490.
    Citations: 72     Fields:    Translation:AnimalsCells
  45. Joukov V, De Nicolo A, Rodriguez A, Walter JC, Livingston DM. Centrosomal protein of 192 kDa (Cep192) promotes centrosome-driven spindle assembly by engaging in organelle-specific Aurora A activation. Proc Natl Acad Sci U S A. 2010 Dec 07; 107(49):21022-7. PMID: 21097701; PMCID: PMC3000277.
    Citations: 48     Fields:    Translation:HumansAnimalsCells
  46. Centore RC, Havens CG, Manning AL, Li JM, Flynn RL, Tse A, Jin J, Dyson NJ, Walter JC, Zou L. CRL4(Cdt2)-mediated destruction of the histone methyltransferase Set8 prevents premature chromatin compaction in S phase. Mol Cell. 2010 Oct 08; 40(1):22-33. PMID: 20932472.
    Citations: 135     Fields:    Translation:HumansAnimalsCells
  47. Lebofsky R, van Oijen AM, Walter JC. DNA is a co-factor for its own replication in Xenopus egg extracts. Nucleic Acids Res. 2011 Jan; 39(2):545-55. PMID: 20861001.
    Citations: 10     Fields:    Translation:AnimalsCells
  48. Fu YV, Walter JC. DNA replication: metazoan Sld3 steps forward. Curr Biol. 2010 Jun 22; 20(12):R515-7. PMID: 20620904.
    Citations: 7     Fields:    Translation:Cells
  49. Knipscheer P, Räschle M, Smogorzewska A, Enoiu M, Ho TV, Schärer OD, Elledge SJ, Walter JC. The Fanconi anemia pathway promotes replication-dependent DNA interstrand cross-link repair. Science. 2009 Dec 18; 326(5960):1698-701. PMID: 19965384; PMCID: PMC2909596.
    Citations: 301     Fields:    Translation:AnimalsCells
  50. Havens CG, Walter JC. Docking of a specialized PIP Box onto chromatin-bound PCNA creates a degron for the ubiquitin ligase CRL4Cdt2. Mol Cell. 2009 Jul 10; 35(1):93-104. PMID: 19595719.
    Citations: 104     Fields:    Translation:HumansAnimalsCells
  51. Kochaniak AB, Habuchi S, Loparo JJ, Chang DJ, Cimprich KA, Walter JC, van Oijen AM. Proliferating cell nuclear antigen uses two distinct modes to move along DNA. J Biol Chem. 2009 Jun 26; 284(26):17700-10. PMID: 19411704.
    Citations: 72     Fields:    Translation:AnimalsCells
  52. Lebofsky R, Takahashi T, Walter JC. DNA replication in nucleus-free Xenopus egg extracts. Methods Mol Biol. 2009; 521:229-52. PMID: 19563110.
    Citations: 59     Fields:    Translation:AnimalsCells
  53. Räschle M, Knipscheer P, Knipsheer P, Enoiu M, Angelov T, Sun J, Griffith JD, Ellenberger TE, Schärer OD, Walter JC. Mechanism of replication-coupled DNA interstrand crosslink repair. Cell. 2008 Sep 19; 134(6):969-80. PMID: 18805090; PMCID: PMC2748255.
    Citations: 292     Fields:    Translation:AnimalsCells
  54. Takahashi TS, Basu A, Bermudez V, Hurwitz J, Walter JC. Cdc7-Drf1 kinase links chromosome cohesion to the initiation of DNA replication in Xenopus egg extracts. Genes Dev. 2008 Jul 15; 22(14):1894-905. PMID: 18628396; PMCID: PMC2492736.
    Citations: 66     Fields:    Translation:AnimalsCells
  55. Lebofsky R, Walter JC. New Myc-anisms for DNA replication and tumorigenesis? Cancer Cell. 2007 Aug; 12(2):102-3. PMID: 17692801.
    Citations: 12     Fields:    Translation:HumansAnimalsCells
  56. Arias EE, Walter JC. Strength in numbers: preventing rereplication via multiple mechanisms in eukaryotic cells. Genes Dev. 2007 Mar 01; 21(5):497-518. PMID: 17344412.
    Citations: 222     Fields:    Translation:HumansAnimalsCells
  57. Joukov V, Groen AC, Prokhorova T, Gerson R, White E, Rodriguez A, Walter JC, Livingston DM. The BRCA1/BARD1 heterodimer modulates ran-dependent mitotic spindle assembly. Cell. 2006 Nov 03; 127(3):539-52. PMID: 17081976.
    Citations: 136     Fields:    Translation:HumansAnimalsCells
  58. Jin J, Arias EE, Chen J, Harper JW, Walter JC. A family of diverse Cul4-Ddb1-interacting proteins includes Cdt2, which is required for S phase destruction of the replication factor Cdt1. Mol Cell. 2006 Sep 01; 23(5):709-21. PMID: 16949367.
    Citations: 343     Fields:    Translation:HumansAnimalsCells
  59. Pacek M, Tutter AV, Kubota Y, Takisawa H, Walter JC. Localization of MCM2-7, Cdc45, and GINS to the site of DNA unwinding during eukaryotic DNA replication. Mol Cell. 2006 Feb 17; 21(4):581-7. PMID: 16483939.
    Citations: 203     Fields:    Translation:AnimalsCells
  60. Barbera AJ, Chodaparambil JV, Kelley-Clarke B, Joukov V, Walter JC, Luger K, Kaye KM. The nucleosomal surface as a docking station for Kaposi's sarcoma herpesvirus LANA. Science. 2006 Feb 10; 311(5762):856-61. PMID: 16469929.
    Citations: 281     Fields:    Translation:HumansAnimalsCells
  61. Cvetic CA, Walter JC. Getting a grip on licensing: mechanism of stable Mcm2-7 loading onto replication origins. Mol Cell. 2006 Jan 20; 21(2):143-4. PMID: 16427002.
    Citations: 12     Fields:    Translation:AnimalsCells
  62. Arias EE, Walter JC. PCNA functions as a molecular platform to trigger Cdt1 destruction and prevent re-replication. Nat Cell Biol. 2006 Jan; 8(1):84-90. PMID: 16362051.
    Citations: 171     Fields:    Translation:AnimalsCells
  63. Takahashi TS, Walter JC. Cdc7-Drf1 is a developmentally regulated protein kinase required for the initiation of vertebrate DNA replication. Genes Dev. 2005 Oct 01; 19(19):2295-300. PMID: 16204181; PMCID: PMC1240038.
    Citations: 37     Fields:    Translation:AnimalsCells
  64. Takahashi TS, Wigley DB, Walter JC. Pumps, paradoxes and ploughshares: mechanism of the MCM2-7 DNA helicase. Trends Biochem Sci. 2005 Aug; 30(8):437-44. PMID: 16002295.
    Citations: 80     Fields:    Translation:HumansAnimalsCells
  65. Cvetic C, Walter JC. Eukaryotic origins of DNA replication: could you please be more specific? Semin Cell Dev Biol. 2005 Jun; 16(3):343-53. PMID: 15840443.
    Citations: 44     Fields:    Translation:AnimalsCells
  66. Arias EE, Walter JC. Replication-dependent destruction of Cdt1 limits DNA replication to a single round per cell cycle in Xenopus egg extracts. Genes Dev. 2005 Jan 01; 19(1):114-26. PMID: 15598982; PMCID: PMC540230.
    Citations: 99     Fields:    Translation:AnimalsCells
  67. Takahashi TS, Yiu P, Chou MF, Gygi S, Walter JC. Recruitment of Xenopus Scc2 and cohesin to chromatin requires the pre-replication complex. Nat Cell Biol. 2004 Oct; 6(10):991-6. PMID: 15448702.
    Citations: 98     Fields:    Translation:AnimalsCells
  68. Arias EE, Walter JC. Initiation of DNA replication in Xenopus egg extracts. Front Biosci. 2004 Sep 01; 9:3029-45. PMID: 15353335.
    Citations: 13     Fields:    Translation:AnimalsCells
  69. Pacek M, Walter JC. A requirement for MCM7 and Cdc45 in chromosome unwinding during eukaryotic DNA replication. EMBO J. 2004 Sep 15; 23(18):3667-76. PMID: 15329670; PMCID: PMC517609.
    Citations: 117     Fields:    Translation:AnimalsCells
  70. Ramachandran N, Hainsworth E, Bhullar B, Eisenstein S, Rosen B, Lau AY, Walter JC, LaBaer J. Self-assembling protein microarrays. Science. 2004 Jul 02; 305(5680):86-90. PMID: 15232106.
    Citations: 148     Fields:    Translation:HumansCells
  71. Pacek M, Prokhorova TA, Walter JC. Cdk1: unsung hero of S phase? Cell Cycle. 2004 Apr; 3(4):401-3. PMID: 14752273.
    Citations: 5     Fields:    Translation:AnimalsCells
  72. Prokhorova TA, Mowrer K, Gilbert CH, Walter JC. DNA replication of mitotic chromatin in Xenopus egg extracts. Proc Natl Acad Sci U S A. 2003 Nov 11; 100(23):13241-6. PMID: 14597706; PMCID: PMC263766.
    Citations: 15     Fields:    Translation:HumansAnimalsCells
  73. Vashee S, Cvetic C, Lu W, Simancek P, Kelly TJ, Walter JC. Sequence-independent DNA binding and replication initiation by the human origin recognition complex. Genes Dev. 2003 Aug 01; 17(15):1894-908. PMID: 12897055; PMCID: PMC196240.
    Citations: 156     Fields:    Translation:HumansAnimalsCells
  74. Van Hatten RA, Tutter AV, Holway AH, Khederian AM, Walter JC, Michael WM. The Xenopus Xmus101 protein is required for the recruitment of Cdc45 to origins of DNA replication. J Cell Biol. 2002 Nov 25; 159(4):541-7. PMID: 12438414; PMCID: PMC2173091.
    Citations: 61     Fields:    Translation:HumansAnimalsCells
  75. Chou DM, Petersen P, Walter JC, Walter G. Protein phosphatase 2A regulates binding of Cdc45 to the prereplication complex. J Biol Chem. 2002 Oct 25; 277(43):40520-7. PMID: 12185086.
    Citations: 14     Fields:    Translation:Cells
  76. Edwards MC, Tutter AV, Cvetic C, Gilbert CH, Prokhorova TA, Walter JC. MCM2-7 complexes bind chromatin in a distributed pattern surrounding the origin recognition complex in Xenopus egg extracts. J Biol Chem. 2002 Sep 06; 277(36):33049-57. PMID: 12087101.
    Citations: 137     Fields:    Translation:AnimalsCells
  77. Wohlschlegel JA, Dhar SK, Prokhorova TA, Dutta A, Walter JC. Xenopus Mcm10 binds to origins of DNA replication after Mcm2-7 and stimulates origin binding of Cdc45. Mol Cell. 2002 Feb; 9(2):233-40. PMID: 11864598.
    Citations: 97     Fields:    Translation:AnimalsCells
  78. Wohlschlegel JA, Dwyer BT, Dhar SK, Cvetic C, Walter JC, Dutta A. Inhibition of eukaryotic DNA replication by geminin binding to Cdt1. Science. 2000 Dec 22; 290(5500):2309-12. PMID: 11125146.
    Citations: 290     Fields:    Translation:HumansAnimalsCells
  79. Walter JC. Evidence for sequential action of cdc7 and cdk2 protein kinases during initiation of DNA replication in Xenopus egg extracts. J Biol Chem. 2000 Dec 15; 275(50):39773-8. PMID: 11005825.
    Citations: 78     Fields:    Translation:AnimalsCells
  80. Walter J, Newport J. Initiation of eukaryotic DNA replication: origin unwinding and sequential chromatin association of Cdc45, RPA, and DNA polymerase alpha. Mol Cell. 2000 Apr; 5(4):617-27. PMID: 10882098.
    Citations: 173     Fields:    Translation:AnimalsCells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.