Harvard Catalyst Profiles

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Vladimir A. Novitsky, Ph.D., M.D.

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Research
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. R21AI138812 (NOVITSKY, VLADIMIR A) Jul 2, 2018 - Jun 30, 2020
    NIH/NIAID
    Pilot Study to Monitor HIV Cluster Dynamics and Active HIV sub-Epidemics in Real Time
    Role: Principal Investigator
  2. R21AI087493 (NOVITSKY, VLADIMIR A) May 15, 2010 - Apr 30, 2012
    NIH/NIAID
    Mutational pathways in early HIV infection: novel guide to immunologic analyses
    Role: Principal Investigator
  3. R01AI057027 (NOVITSKY, VLADIMIR A) May 1, 2005 - Apr 30, 2011
    NIH/NIAID
    Markers of Viral Set Point in Primary HIV-1C Infection
    Role: Principal Investigator
  4. R21AI055297 (NOVITSKY, VLADIMIR A) Jul 1, 2003 - Jun 30, 2005
    NIH/NIAID
    Early and acute HIV-1 subtype C infection in Botswana
    Role: Principal Investigator

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Mogashoa T, Melamu P, Ley SD, Streicher EM, Iketleng T, Kelentse N, Mupfumi L, Mokomane M, Kgwaadira B, Novitsky V, Kasvosve I, Moyo S, Warren RM, Gaseitsiwe S. Genetic diversity of Mycobacterium tuberculosis strains circulating in Botswana. PLoS One. 2019; 14(5):e0216306. PMID: 31063472.
    Citations:    
  2. Moyo S, Gaseitsiwe S, Zahralban-Steele M, Maruapula D, Nkhisang T, Mokaleng B, Mohammed T, Ditlhako TR, Bareng OT, Mokgethi TP, van Widenfelt E, Pretorius-Holme M, Mine MO, Raizes E, Yankinda EK, Wirth KE, Gaolathe T, Makhema JM, Lockman S, Essex M, Novitsky V. Low rates of nucleoside reverse transcriptase inhibitor and nonnucleoside reverse transcriptase inhibitor drug resistance in Botswana. AIDS. 2019 May 01; 33(6):1073-1082. PMID: 30946161.
    Citations:    
  3. Moyo S, Gaseitsiwe S, Zahralban-Steele M, Maruapula D, Nkhisang T, Mokaleng B, Mohammed T, Ditlhako TR, Bareng OT, Mokgethi TP, van Widenfelt E, Pretorius-Holme M, Mine MO, Raizes E, Yankinda EK, Wirth KE, Gaolathe T, Makhema JM, Lockman S, Essex M, Novitsky V. Low rates of NRTI and NNRTI drug resistance among participants in the Botswana combination prevention program (BCPP) trial. AIDS. 2019 Feb 07. PMID: 30741821.
    Citations:    
  4. Ojwach DBA, MacMillan D, Reddy T, Novitsky V, Brumme ZL, Brockman MA, Ndung'u T, Mann JK. Correction for Ojwach et al., "Pol-Driven Replicative Capacity Impacts Disease Progression in HIV-1 Subtype C Infection". J Virol. 2019 Feb 01; 93(3). PMID: 30655384.
    Citations:    Fields:    
  5. Vasylyeva TI, Liulchuk M, du Plessis L, Fearnhill E, Zadorozhna V, Babii N, Scherbinska A, Novitsky V, Pybus OG, Faria NR. The Changing Epidemiological Profile of HIV-1 Subtype B Epidemic in Ukraine. AIDS Res Hum Retroviruses. 2019 Feb; 35(2):155-163. PMID: 30430838.
    Citations:    Fields:    
  6. Moyo S, Gaseitsiwe S, Mohammed T, Pretorius Holme M, Wang R, Kotokwe KP, Boleo C, Mupfumi L, Yankinda EK, Chakalisa U, van Widenfelt E, Gaolathe T, Mmalane MO, Dryden-Peterson S, Mine M, Lebelonyane R, Bennett K, Leidner J, Wirth KE, Tchetgen Tchetgen E, Powis K, Moore J, Clarke WA, Lockman S, Makhema JM, Essex M, Novitsky V. Cross-sectional estimates revealed high HIV incidence in Botswana rural communities in the era of successful ART scale-up in 2013-2015. PLoS One. 2018; 13(10):e0204840. PMID: 30356287.
    Citations:    Fields:    
  7. Ojwach DBA, MacMillan D, Reddy T, Novitsky V, Brumme ZL, Brockman MA, Ndung'u T, Mann JK. Pol-Driven Replicative Capacity Impacts Disease Progression in HIV-1 Subtype C Infection. J Virol. 2018 10 01; 92(19). PMID: 29997209.
    Citations:    Fields:    Translation:HumansCells
  8. Novitsky V, Gaolathe T, Mmalane M, Moyo S, Chakalisa U, Yankinda EK, Marukutira T, Holme MP, Sekoto T, Gaseitsiwe S, Musonda R, van Widenfelt E, Powis KM, Khan N, Dryden-Peterson S, Bennett K, Wirth KE, Tchetgen ET, Bachanas P, Mills LA, Lebelonyane R, El-Halabi S, Makhema J, Lockman S, Essex M. Lack of Virological Suppression Among Young HIV-Positive Adults in Botswana. J Acquir Immune Defic Syndr. 2018 Aug 15; 78(5):557-565. PMID: 29771781.
    Citations:    Fields:    
  9. Moyo S, Gaseitsiwe S, Powis KM, Pretorius Holme M, Mohammed T, Zahralban-Steele M, Yankinde EK, Maphorisa C, Abrams W, Lebelonyane R, Manyake K, Sekoto T, Mmalane M, Gaolathe T, Wirth KE, Makhema J, Lockman S, Clarke W, Essex M, Novitsky V. Undisclosed antiretroviral drug use in Botswana: implication for national estimates. AIDS. 2018 Jul 17; 32(11):1543-1546. PMID: 29762166.
    Citations:    Fields:    
  10. Diphoko T, Gaseitsiwe S, Kasvosve I, Moyo S, Okatch H, Musonda R, Wainberg M, Makhema J, Marlink R, Novitsky V, Essex M. Prevalence of Rilpivirine and Etravirine Resistance Mutations in HIV-1 Subtype C-Infected Patients Failing Nevirapine or Efavirenz-Based Combination Antiretroviral Therapy in Botswana. AIDS Res Hum Retroviruses. 2018 08; 34(8):667-671. PMID: 29732907.
    Citations:    Fields:    
  11. Novitsky V, Prague M, Moyo S, Gaolathe T, Mmalane M, Yankinda EK, Chakalisa U, Lebelonyane R, Khan N, Powis KM, Widenfelt E, Gaseitsiwe S, Dryden-Peterson SL, Holme MP, De Gruttola V, Bachanas P, Makhema J, Lockman S, Essex M. High HIV-1 RNA Among Newly Diagnosed People in Botswana. AIDS Res Hum Retroviruses. 2018 03; 34(3):300-306. PMID: 29214845.
    Citations:    Fields:    
  12. Ratmann O, Wymant C, Colijn C, Danaviah S, Essex M, Frost SDW, Gall A, Gaiseitsiwe S, Grabowski M, Gray R, Guindon S, von Haeseler A, Kaleebu P, Kendall M, Kozlov A, Manasa J, Minh BQ, Moyo S, Novitsky V, Nsubuga R, Pillay S, Quinn TC, Serwadda D, Ssemwanga D, Stamatakis A, Trifinopoulos J, Wawer M, Leigh Brown A, de Oliveira T, Kellam P, Pillay D, Fraser C. HIV-1 full-genome phylogenetics of generalized epidemics in sub-Saharan Africa: impact of missing nucleotide characters in next-generation sequences. AIDS Res Hum Retroviruses. 2017 11; 33(11):1083-1098. PMID: 28540766.
    Citations: 1     Fields:    
  13. Xie W, Agniel D, Shevchenko A, Malov SV, Svitin A, Cherkasov N, Baum MK, Campa A, Gaseitsiwe S, Bussmann H, Makhema J, Marlink R, Novitsky V, Lee TH, Cai T, O'Brien SJ, Essex M. Genome-Wide Analyses Reveal Gene Influence on HIV Disease Progression and HIV-1C Acquisition in Southern Africa. AIDS Res Hum Retroviruses. 2017 06; 33(6):597-609. PMID: 28132517.
    Citations: 1     Fields:    Translation:HumansCells
  14. Moyo S, Wilkinson E, Vandormael A, Wang R, Weng J, Kotokwe KP, Gaseitsiwe S, Musonda R, Makhema J, Essex M, Engelbrecht S, de Oliveira T, Novitsky V. Pairwise diversity and tMRCA as potential markers for HIV infection recency. Medicine (Baltimore). 2017 Feb; 96(6):e6041. PMID: 28178146.
    Citations: 1     Fields:    Translation:HumansCells
  15. Novitsky V, Moyo S, Wang R, Gaseitsiwe S, Essex M. Deciphering Multiplicity of HIV-1C Infection: Transmission of Closely Related Multiple Viral Lineages. PLoS One. 2016; 11(11):e0166746. PMID: 27893822.
    Citations: 1     Fields:    Translation:HumansCells
  16. Moyo S, Mohammed T, Wirth KE, Prague M, Bennett K, Holme MP, Mupfumi L, Sebogodi P, Moraka NO, Boleo C, Maphorisa CN, Seraise B, Gaseitsiwe S, Musonda RM, van Widenfelt E, Powis KM, Gaolathe T, Tchetgen Tchetgen EJ, Makhema JM, Essex M, Lockman S, Novitsky V. Point-of-Care Cepheid Xpert HIV-1 Viral Load Test in Rural African Communities Is Feasible and Reliable. J Clin Microbiol. 2016 12; 54(12):3050-3055. PMID: 27733636.
    Citations: 2     Fields:    Translation:HumansCells
  17. Moyo S, Kotokwe KP, Mohammed T, Boleo C, Mupfumi L, Chishala S, Tsalaile L, Bussmann H, Gaseitsiwe S, Musonda R, Makhema J, Baum M, Marlink R, Engelbrecht S, Essex M, Novitsky V. Short Communication: Low False Recent Rate of Limiting Antigen-Avidity Assay Combined with HIV-1 RNA Data in Botswana. AIDS Res Hum Retroviruses. 2017 01; 33(1):17-18. PMID: 27481530.
    Citations:    Fields:    Translation:Humans
  18. Moyo S, Vandormael A, Wilkinson E, Engelbrecht S, Gaseitsiwe S, Kotokwe KP, Musonda R, Tanser F, Essex M, Novitsky V, de Oliveira T. Analysis of Viral Diversity in Relation to the Recency of HIV-1C Infection in Botswana. PLoS One. 2016; 11(8):e0160649. PMID: 27552218.
    Citations: 2     Fields:    Translation:HumansCells
  19. Rossenkhan R, MacLeod IJ, Brumme ZL, Magaret CA, Sebunya TK, Musonda R, Gashe BA, Edlefsen PT, Novitsky V, Essex M. Transmitted/Founder HIV-1 Subtype C Viruses Show Distinctive Signature Patterns in Vif, Vpr, and Vpu That Are Under Subsequent Immune Pressure During Early Infection. AIDS Res Hum Retroviruses. 2016 Oct/Nov; 32(10-11):1031-1045. PMID: 27349335.
    Citations:    Fields:    Translation:HumansCells
  20. Novitsky V, Zahralban-Steele M, McLane MF, Moyo S, van Widenfelt E, Gaseitsiwe S, Makhema J, Essex M. Correction for Novitsky et al., Long-Range HIV Genotyping Using Viral RNA and Proviral DNA for Analysis of HIV Drug Resistance and HIV Clustering. J Clin Microbiol. 2016 Apr; 54(4):1175. PMID: 27016593.
    Citations:    Fields:    
  21. Gaolathe T, Wirth KE, Holme MP, Makhema J, Moyo S, Chakalisa U, Yankinda EK, Lei Q, Mmalane M, Novitsky V, Okui L, van Widenfelt E, Powis KM, Khan N, Bennett K, Bussmann H, Dryden-Peterson S, Lebelonyane R, El-Halabi S, Mills LA, Marukutira T, Wang R, Tchetgen EJ, DeGruttola V, Essex M, Lockman S. Botswana's progress toward achieving the 2020 UNAIDS 90-90-90 antiretroviral therapy and virological suppression goals: a population-based survey. Lancet HIV. 2016 May; 3(5):e221-30. PMID: 27126489.
    Citations: 28     Fields:    
  22. Farahani M, Novitsky V, Wang R, Bussmann H, Moyo S, Musonda RM, Moeti T, Makhema JM, Essex M, Marlink R. Prognostic Value of HIV-1 RNA on CD4 Trajectories and Disease Progression Among Antiretroviral-Naive HIV-Infected Adults in Botswana: A Joint Modeling Analysis. AIDS Res Hum Retroviruses. 2016 06; 32(6):573-8. PMID: 26830351.
    Citations: 3     Fields:    Translation:Humans
  23. Moyo S, Wilkinson E, Novitsky V, Vandormael A, Gaseitsiwe S, Essex M, Engelbrecht S, de Oliveira T. Identifying Recent HIV Infections: From Serological Assays to Genomics. Viruses. 2015 Oct 23; 7(10):5508-24. PMID: 26512688.
    Citations: 8     Fields:    Translation:Humans
  24. Wu JW, Patterson-Lomba O, Novitsky V, Pagano M. A Generalized Entropy Measure of Within-Host Viral Diversity for Identifying Recent HIV-1 Infections. Medicine (Baltimore). 2015 Oct; 94(42):e1865. PMID: 26496342.
    Citations: 3     Fields:    Translation:HumansCells
  25. Novitsky V, Kühnert D, Moyo S, Widenfelt E, Okui L, Essex M. Phylodynamic analysis of HIV sub-epidemics in Mochudi, Botswana. Epidemics. 2015 Dec; 13:44-55. PMID: 26616041.
    Citations: 3     Fields:    Translation:HumansPHPublic Health
  26. Liu SH, Erion G, Novitsky V, De Gruttola V. Viral Genetic Linkage Analysis in the Presence of Missing Data. PLoS One. 2015; 10(8):e0135469. PMID: 26301919.
    Citations:    Fields:    Translation:HumansCells
  27. Novitsky V, Zahralban-Steele M, McLane MF, Moyo S, van Widenfelt E, Gaseitsiwe S, Makhema J, Essex M. Long-Range HIV Genotyping Using Viral RNA and Proviral DNA for Analysis of HIV Drug Resistance and HIV Clustering. J Clin Microbiol. 2015 Aug; 53(8):2581-92. PMID: 26041893.
    Citations:    Fields:    Translation:HumansCells
  28. Novitsky V, Bussmann H, Okui L, Logan A, Moyo S, van Widenfelt E, Mmalane M, Lei Q, Holme MP, Makhema J, Lockman S, Degruttola V, Essex M. Estimated age and gender profile of individuals missed by a home-based HIV testing and counselling campaign in a Botswana community. J Int AIDS Soc. 2015; 18:19918. PMID: 26028155.
    Citations: 2     Fields:    Translation:HumansCells
  29. Novitsky V, Moyo S, Lei Q, DeGruttola V, Essex M. Importance of Viral Sequence Length and Number of Variable and Informative Sites in Analysis of HIV Clustering. AIDS Res Hum Retroviruses. 2015 May; 31(5):531-42. PMID: 25560745.
    Citations: 2     Fields:    Translation:HumansCells
  30. Novitsky V, Moyo S, Lei Q, DeGruttola V, Essex M. Impact of sampling density on the extent of HIV clustering. AIDS Res Hum Retroviruses. 2014 Dec; 30(12):1226-35. PMID: 25275430.
    Citations: 14     Fields:    Translation:HumansCells
  31. Mann JK, Chopera D, Omarjee S, Kuang XT, Le AQ, Anmole G, Danroth R, Mwimanzi P, Reddy T, Carlson J, Radebe M, Goulder PJR, Walker BD, Abdool Karim S, Novitsky V, Williamson C, Brockman MA, Brumme ZL, Ndung'u T. Nef-mediated down-regulation of CD4 and HLA class I in HIV-1 subtype C infection: association with disease progression and influence of immune pressure. Virology. 2014 Nov; 468-470:214-225. PMID: 25193656.
    Citations: 5     Fields:    Translation:HumansCells
  32. Kiwelu IE, Novitsky V, Kituma E, Margolin L, Baca J, Manongi R, Sam N, Shao J, McLane MF, Kapiga SH, Essex M. HIV-1 pol diversity among female bar and hotel workers in Northern Tanzania. PLoS One. 2014; 9(7):e102258. PMID: 25003939.
    Citations: 2     Fields:    Translation:HumansCells
  33. Carnegie NB, Wang R, Novitsky V, De Gruttola V. Linkage of viral sequences among HIV-infected village residents in Botswana: estimation of linkage rates in the presence of missing data. PLoS Comput Biol. 2014 Jan; 10(1):e1003430. PMID: 24415932.
    Citations: 5     Fields:    Translation:HumansCellsPHPublic Health
  34. Novitsky V, Bussmann H, Logan A, Moyo S, van Widenfelt E, Okui L, Mmalane M, Baca J, Buck L, Phillips E, Tim D, McLane MF, Lei Q, Wang R, Makhema J, Lockman S, DeGruttola V, Essex M. Phylogenetic relatedness of circulating HIV-1C variants in Mochudi, Botswana. PLoS One. 2013; 8(12):e80589. PMID: 24349005.
    Citations: 6     Fields:    Translation:HumansCells
  35. Moyo S, LeCuyer T, Wang R, Gaseitsiwe S, Weng J, Musonda R, Bussmann H, Mine M, Engelbrecht S, Makhema J, Marlink R, Baum MK, Novitsky V, Essex M. Evaluation of the false recent classification rates of multiassay algorithms in estimating HIV type 1 subtype C incidence. AIDS Res Hum Retroviruses. 2014 Jan; 30(1):29-36. PMID: 23937344.
    Citations: 7     Fields:    Translation:HumansCells
  36. Kiwelu IE, Novitsky V, Margolin L, Baca J, Manongi R, Sam N, Shao J, McLane MF, Kapiga SH, Essex M. Frequent intra-subtype recombination among HIV-1 circulating in Tanzania. PLoS One. 2013; 8(8):e71131. PMID: 23940702.
    Citations: 5     Fields:    Translation:HumansCells
  37. McDonald B, Moyo S, Gabaitiri L, Gaseitsiwe S, Bussmann H, Koethe JR, Musonda R, Makhema J, Novitsky V, Marlink RG, Wester CW, Essex M. Persistently elevated serum interleukin-6 predicts mortality among adults receiving combination antiretroviral therapy in Botswana: results from a clinical trial. AIDS Res Hum Retroviruses. 2013 Jul; 29(7):993-9. PMID: 23590237.
    Citations: 16     Fields:    Translation:HumansCells
  38. Wang R, Weng J, Moyo S, Pain D, Barr CD, Maruapula D, Mongwato D, Makhema J, Novitsky V, Essex M. Short communication: effect of short-course antenatal zidovudine and single-dose nevirapine on the BED capture enzyme immunoassay levels in HIV type 1 subtype C infection. AIDS Res Hum Retroviruses. 2013 Jun; 29(6):901-6. PMID: 23521375.
    Citations: 1     Fields:    Translation:HumansCells
  39. Novitsky V, Wang R, Rossenkhan R, Moyo S, Essex M. Intra-host evolutionary rates in HIV-1C env and gag during primary infection. Infect Genet Evol. 2013 Oct; 19:361-8. PMID: 23523818.
    Citations: 17     Fields:    Translation:HumansCells
  40. Rossenkhan R, MacLeod IJ, Sebunya TK, Castro-Nallar E, McLane MF, Musonda R, Gashe BA, Novitsky V, Essex M. tat Exon 1 exhibits functional diversity during HIV-1 subtype C primary infection. J Virol. 2013 May; 87(10):5732-45. PMID: 23487450.
    Citations: 4     Fields:    Translation:HumansCells
  41. Kiwelu IE, Novitsky V, Margolin L, Baca J, Manongi R, Sam N, Shao J, McLane MF, Kapiga SH, Essex M. HIV-1 subtypes and recombinants in Northern Tanzania: distribution of viral quasispecies. PLoS One. 2012; 7(10):e47605. PMID: 23118882.
    Citations: 10     Fields:    Translation:HumansCells
  42. Lin NH, Becerril C, Giguel F, Novitsky V, Moyo S, Makhema J, Essex M, Lockman S, Kuritzkes DR, Sagar M. Env sequence determinants in CXCR4-using human immunodeficiency virus type-1 subtype C. Virology. 2012 Nov 25; 433(2):296-307. PMID: 22954962.
    Citations: 12     Fields:    Translation:HumansCells
  43. Rossenkhan R, Novitsky V, Sebunya TK, Leidner J, Hagan JE, Moyo S, Smeaton L, Lockman S, Musonda R, Ndung'u T, Gaseitsiwe S, Thior I, Mmalane M, Makhema J, Essex M, Shapiro R. Infant feeding practices were not associated with breast milk HIV-1 RNA levels in a randomized clinical trial in Botswana. AIDS Behav. 2012 Jul; 16(5):1260-4. PMID: 21901486.
    Citations: 5     Fields:    Translation:Humans
  44. Wester CW, Eden SK, Shepherd BE, Bussmann H, Novitsky V, Samuels DC, Hendrickson SL, Winkler CA, O'Brien SJ, Essex M, D'Aquila RT, DeGruttola V, Marlink RG. Risk factors for symptomatic hyperlactatemia and lactic acidosis among combination antiretroviral therapy-treated adults in Botswana: results from a clinical trial. AIDS Res Hum Retroviruses. 2012 Aug; 28(8):759-65. PMID: 22540188.
    Citations: 9     Fields:    Translation:Humans
  45. Rossenkhan R, Novitsky V, Sebunya TK, Musonda R, Gashe BA, Essex M. Viral diversity and diversification of major non-structural genes vif, vpr, vpu, tat exon 1 and rev exon 1 during primary HIV-1 subtype C infection. PLoS One. 2012; 7(5):e35491. PMID: 22590503.
    Citations: 8     Fields:    Translation:HumansCellsCTClinical Trials
  46. Novitsky V, Essex M. Using HIV viral load to guide treatment-for-prevention interventions. Curr Opin HIV AIDS. 2012 Mar; 7(2):117-24. PMID: 22258501.
    Citations: 15     Fields:    Translation:HumansCells
  47. Mine M, Moyo S, Stevens P, Michael K, Novitsky V, Makhaola K, Asmelash A, Molefhabangwe S, Woldegabriel E, Mothowaeng G, Maruta T, Kamhukamwe C, Mangwendeza PM, Holmes-Pretorius M, Mtoni I, Motswaledi M, Musonda R, Ndwapi N, Makhema J, Marlink R, Seipone K, Gaolathe T, Essex M. Immunohaematological reference values for HIV-negative healthy adults in Botswana. Afr J Lab Med. 2012; 1(1). PMID: 23772402.
    Citations: 7     
  48. Mine M, Moyo S, Stevens P, Michael K, Novitsky V, Makhaola K, Asmelash A, Molefhabangwe S, Woldegabriel E, Mothowaeng G, Maruta T, Kamhukamwe C, Mangwendeza PM, Holmes-Pretorius M, Mtoni I, Motswaledi M, Musonda R, Ndwapi N, Makhema J, Marlink R, Seipone K, Gaolathe T, Essex M. Immunohaematological reference values for HIV-negative healthy adults in Botswana. Afr J Lab Med. 2012; 1(1):5. PMID: 29062725.
    Citations: 3     
  49. Novitsky V, Wang R, Baca J, Margolin L, McLane MF, Moyo S, van Widenfelt E, Makhema J, Essex M. Evolutionary gamut of in vivo Gag substitutions during early HIV-1 subtype C infection. Virology. 2011 Dec 20; 421(2):119-28. PMID: 22014506.
    Citations: 2     Fields:    Translation:HumansCells
  50. Moyo S, Bussmann H, Mangwendeza P, Dusara P, Gaolathe T, Mine M, Musonda R, van Widenfelt E, Novitsky V, Makhema J, Marlink RG, Essex M, Wester CW. Validation of A Point-of-Care Lactate Device For Screening At-Risk Adults Receiving Combination Antiretroviral Therapy In Botswana. J Antivir Antiretrovir. 2011 Oct; 3(4):45-48. PMID: 23087782.
    Citations: 2     
  51. Novitsky V, Ndung'u T, Wang R, Bussmann H, Chonco F, Makhema J, De Gruttola V, Walker BD, Essex M. Extended high viremics: a substantial fraction of individuals maintain high plasma viral RNA levels after acute HIV-1 subtype C infection. AIDS. 2011 Jul 31; 25(12):1515-22. PMID: 21505307.
    Citations: 34     Fields:    Translation:HumansCells
  52. Lin NH, Smeaton LM, Giguel F, Novitsky V, Moyo S, Mitchell RM, Makhema J, Essex M, Lockman S, Kuritzkes DR. Prevalence and clinical associations of CXCR4-using HIV-1 among treatment-naive subtype C-infected women in Botswana. J Acquir Immune Defic Syndr. 2011 May 01; 57(1):46-50. PMID: 21346588.
    Citations: 6     Fields:    Translation:HumansCells
  53. Novitsky V, Wang R, Margolin L, Baca J, Rossenkhan R, Moyo S, van Widenfelt E, Essex M. Transmission of single and multiple viral variants in primary HIV-1 subtype C infection. PLoS One. 2011 Feb 09; 6(2):e16714. PMID: 21415914.
    Citations: 24     Fields:    Translation:HumansCells
  54. Wright JK, Novitsky V, Brockman MA, Brumme ZL, Brumme CJ, Carlson JM, Heckerman D, Wang B, Losina E, Leshwedi M, van der Stok M, Maphumulo L, Mkhwanazi N, Chonco F, Goulder PJ, Essex M, Walker BD, Ndung'u T. Influence of Gag-protease-mediated replication capacity on disease progression in individuals recently infected with HIV-1 subtype C. J Virol. 2011 Apr; 85(8):3996-4006. PMID: 21289112.
    Citations: 28     Fields:    Translation:HumansCells
  55. Bussmann H, de la Hoz Gomez F, Roels TH, Wester CW, Bodika SM, Moyo S, Taffa N, Anderson MG, Mine M, Bile EC, Yang C, Mphoyakgosi K, Lehotzky EA, Mlotshwa B, Mmelesi M, Seipone K, Makhema MJ, Marlink RG, Novitsky V, Essex M. Prevalence of transmitted HIV drug resistance in Botswana: lessons learned from the HIVDR-Threshold Survey conducted among women presenting for routine antenatal care as part of the 2007 national sentinel survey. AIDS Res Hum Retroviruses. 2011 Apr; 27(4):365-72. PMID: 21034246.
    Citations: 8     Fields:    Translation:HumansCells
  56. Novitsky V, Wang R, Margolin L, Baca J, Moyo S, Musonda R, Essex M. Dynamics and timing of in vivo mutations at Gag residue 242 during primary HIV-1 subtype C infection. Virology. 2010 Jul 20; 403(1):37-46. PMID: 20444482.
    Citations: 14     Fields:    Translation:HumansAnimalsCells
  57. Novitsky V, Wang R, Bussmann H, Lockman S, Baum M, Shapiro R, Thior I, Wester C, Wester CW, Ogwu A, Asmelash A, Musonda R, Campa A, Moyo S, van Widenfelt E, Mine M, Moffat C, Mmalane M, Makhema J, Marlink R, Gilbert P, Seage GR, DeGruttola V, Essex M. HIV-1 subtype C-infected individuals maintaining high viral load as potential targets for the "test-and-treat" approach to reduce HIV transmission. PLoS One. 2010 Apr 12; 5(4):e10148. PMID: 20405044.
    Citations: 28     Fields:    Translation:AnimalsCellsPHPublic Health
  58. Novitsky V, Wang R, Lagakos S, Essex M. HIV-1 Subtype C Phylodynamics in the Global Epidemic. Viruses. 2010 Jan; 2(1):33-54. PMID: 21994599.
    Citations: 12     Fields:    
  59. Wester CW, Thomas AM, Bussmann H, Moyo S, Makhema JM, Gaolathe T, Novitsky V, Essex M, deGruttola V, Marlink RG. Non-nucleoside reverse transcriptase inhibitor outcomes among combination antiretroviral therapy-treated adults in Botswana. AIDS. 2010 Jan; 24 Suppl 1:S27-36. PMID: 20023437.
    Citations: 19     Fields:    Translation:HumansCells
  60. Rossenkhan R, Ndung'u T, Sebunya TK, Hagan JE, Shapiro R, Novitsky V, Moyo SM, Thior I, Lockman S, Mitchell R, Kim S, Musonda R, van Widenfelt E, Makhema J, Essex M. Temporal reduction of HIV type 1 viral load in breast milk by single-dose nevirapine during prevention of MTCT. AIDS Res Hum Retroviruses. 2009 Dec; 25(12):1261-4. PMID: 20001515.
    Citations: 3     Fields:    Translation:HumansCells
  61. Mast TC, Kierstead L, Gupta SB, Nikas AA, Kallas EG, Novitsky V, Mbewe B, Pitisuttithum P, Schechter M, Vardas E, Wolfe ND, Aste-Amezaga M, Casimiro DR, Coplan P, Straus WL, Shiver JW. International epidemiology of human pre-existing adenovirus (Ad) type-5, type-6, type-26 and type-36 neutralizing antibodies: correlates of high Ad5 titers and implications for potential HIV vaccine trials. Vaccine. 2010 Jan 22; 28(4):950-7. PMID: 19925902.
    Citations: 84     Fields:    Translation:HumansCells
  62. Novitsky V, Wang R, Margolin L, Baca J, Kebaabetswe L, Rossenkhan R, Bonney C, Herzig M, Nkwe D, Moyo S, Musonda R, Woldegabriel E, van Widenfelt E, Makhema J, Lagakos S, Essex M. Timing constraints of in vivo gag mutations during primary HIV-1 subtype C infection. PLoS One. 2009 Nov 05; 4(11):e7727. PMID: 19890401.
    Citations: 21     Fields:    Translation:HumansCells
  63. Novitsky V, Wang R, Kebaabetswe L, Greenwald J, Rossenkhan R, Moyo S, Musonda R, Woldegabriel E, Lagakos S, Essex M. Better control of early viral replication is associated with slower rate of elicited antiviral antibodies in the detuned enzyme immunoassay during primary HIV-1C infection. J Acquir Immune Defic Syndr. 2009 Oct 01; 52(2):265-72. PMID: 19525854.
    Citations: 22     Fields:    Translation:HumansCells
  64. Bussmann H, Wester CW, Thomas A, Novitsky V, Okezie R, Muzenda T, Gaolathe T, Ndwapi N, Mawoko N, Widenfelt E, Moyo S, Musonda R, Mine M, Makhema J, Moffat H, Essex M, Degruttola V, Marlink RG. Response to zidovudine/didanosine-containing combination antiretroviral therapy among HIV-1 subtype C-infected adults in Botswana: two-year outcomes from a randomized clinical trial. J Acquir Immune Defic Syndr. 2009 May 01; 51(1):37-46. PMID: 19282782.
    Citations: 24     Fields:    Translation:HumansCells
  65. Shapiro RL, Smeaton L, Lockman S, Thior I, Rossenkhan R, Wester C, Stevens L, Moffat C, Arimi P, Ndase P, Asmelash A, Leidner J, Novitsky V, Makhema J, Essex M. Risk factors for early and late transmission of HIV via breast-feeding among infants born to HIV-infected women in a randomized clinical trial in Botswana. J Infect Dis. 2009 Feb 01; 199(3):414-8. PMID: 19090775.
    Citations: 11     Fields:    Translation:HumansCells
  66. Novitsky V, Woldegabriel E, Kebaabetswe L, Rossenkhan R, Mlotshwa B, Bonney C, Finucane M, Musonda R, Moyo S, Wester C, van Widenfelt E, Makhema J, Lagakos S, Essex M. Viral load and CD4+ T-cell dynamics in primary HIV-1 subtype C infection. J Acquir Immune Defic Syndr. 2009 Jan 01; 50(1):65-76. PMID: 19295336.
    Citations: 26     Fields:    Translation:HumansCells
  67. Novitsky V, Lagakos S, Herzig M, Bonney C, Kebaabetswe L, Rossenkhan R, Nkwe D, Margolin L, Musonda R, Moyo S, Woldegabriel E, van Widenfelt E, Makhema J, Essex M. Evolution of proviral gp120 over the first year of HIV-1 subtype C infection. Virology. 2009 Jan 05; 383(1):47-59. PMID: 18973914.
    Citations: 24     Fields:    Translation:HumansCells
  68. Novitsky V, Woldegabriel E, Wester C, McDonald E, Rossenkhan R, Ketunuti M, Makhema J, Seage GR, Essex M. Identification of primary HIV-1C infection in Botswana. AIDS Care. 2008 Aug; 20(7):806-11. PMID: 18608056.
    Citations: 22     Fields:    Translation:HumansCells
  69. Wester CW, Okezie OA, Thomas AM, Bussmann H, Moyo S, Muzenda T, Makhema J, van Widenfelt E, Musonda R, Novitsky V, Gaolathe T, Ndwapi N, Essex M, Kuritzkes DR, DeGruttola V, Marlink RG. Higher-than-expected rates of lactic acidosis among highly active antiretroviral therapy-treated women in Botswana: preliminary results from a large randomized clinical trial. J Acquir Immune Defic Syndr. 2007 Nov 01; 46(3):318-22. PMID: 18090299.
    Citations: 33     Fields:    Translation:Humans
  70. Novitsky V, Gaolathe T, Woldegabriel E, Makhema J, Essex M. A seronegative case of HIV-1 subtype C infection in Botswana. Clin Infect Dis. 2007 Sep 01; 45(5):e68-71. PMID: 17682982.
    Citations: 6     Fields:    Translation:HumansCells
  71. Novitsky V, Wester CW, DeGruttola V, Bussmann H, Gaseitsiwe S, Thomas A, Moyo S, Musonda R, Van Widenfelt E, Marlink RG, Essex M. The reverse transcriptase 67N 70R 215Y genotype is the predominant TAM pathway associated with virologic failure among HIV type 1C-infected adults treated with ZDV/ddI-containing HAART in southern Africa. AIDS Res Hum Retroviruses. 2007 Jul; 23(7):868-78. PMID: 17678469.
    Citations: 32     Fields:    Translation:HumansCells
  72. Lockman S, Shapiro RL, Smeaton LM, Wester C, Thior I, Stevens L, Chand F, Makhema J, Moffat C, Asmelash A, Ndase P, Arimi P, van Widenfelt E, Mazhani L, Novitsky V, Lagakos S, Essex M. Response to antiretroviral therapy after a single, peripartum dose of nevirapine. N Engl J Med. 2007 Jan 11; 356(2):135-47. PMID: 17215531.
    Citations: 135     Fields:    Translation:HumansCells
  73. O'Neill E, Baugh LL, Novitsky VA, Essex ME, Garcia JV. Intra- and intersubtype alternative Pak2-activating structural motifs of human immunodeficiency virus type 1 Nef. J Virol. 2006 Sep; 80(17):8824-9. PMID: 16912329.
    Citations: 4     Fields:    Translation:HumansCells
  74. Thior I, Lockman S, Smeaton LM, Shapiro RL, Wester C, Heymann SJ, Gilbert PB, Stevens L, Peter T, Kim S, van Widenfelt E, Moffat C, Ndase P, Arimi P, Kebaabetswe P, Mazonde P, Makhema J, McIntosh K, Novitsky V, Lee TH, Marlink R, Lagakos S, Essex M. Breastfeeding plus infant zidovudine prophylaxis for 6 months vs formula feeding plus infant zidovudine for 1 month to reduce mother-to-child HIV transmission in Botswana: a randomized trial: the Mashi Study. JAMA. 2006 Aug 16; 296(7):794-805. PMID: 16905785.
    Citations: 121     Fields:    Translation:HumansCells
  75. Shapiro RL, Thior I, Gilbert PB, Lockman S, Wester C, Smeaton LM, Stevens L, Heymann SJ, Ndung'u T, Gaseitsiwe S, Novitsky V, Makhema J, Lagakos S, Essex M. Maternal single-dose nevirapine versus placebo as part of an antiretroviral strategy to prevent mother-to-child HIV transmission in Botswana. AIDS. 2006 Jun 12; 20(9):1281-8. PMID: 16816557.
    Citations: 29     Fields:    Translation:HumansCells
  76. Gupta SB, Mast CT, Wolfe ND, Novitsky V, Dubey SA, Kallas EG, Schechter M, Mbewe B, Vardas E, Pitisuttithum P, Burke D, Freed D, Mogg R, Coplan PM, Condra JH, Long RS, Anderson K, Casimiro DR, Shiver JW, Straus WL. Cross-clade reactivity of HIV-1-specific T-cell responses in HIV-1-infected individuals from Botswana and Cameroon. J Acquir Immune Defic Syndr. 2006 Jun; 42(2):135-9. PMID: 16760794.
    Citations: 8     Fields:    Translation:HumansCells
  77. Doualla-Bell F, Avalos A, Gaolathe T, Mine M, Gaseitsiwe S, Ndwapi N, Novitsky VA, Brenner B, Oliveira M, Moisi D, Moffat H, Thior I, Essex M, Wainberg MA. Impact of human immunodeficiency virus type 1 subtype C on drug resistance mutations in patients from Botswana failing a nelfinavir-containing regimen. Antimicrob Agents Chemother. 2006 Jun; 50(6):2210-3. PMID: 16723586.
    Citations: 11     Fields:    Translation:HumansCells
  78. Da'Dara AA, Lautsch N, Dudek T, Novitsky V, Lee TH, Essex M, Harn DA. Helminth infection suppresses T-cell immune response to HIV-DNA-based vaccine in mice. Vaccine. 2006 Jun 12; 24(24):5211-9. PMID: 16675073.
    Citations: 13     Fields:    Translation:AnimalsCells
  79. Novitsky VA, Gilbert PB, Shea K, McLane MF, Rybak N, Klein I, Thior I, Ndung'u T, Lee TH, Essex ME. Interactive association of proviral load and IFN-gamma-secreting T cell responses in HIV-1C infection. Virology. 2006 May 25; 349(1):142-55. PMID: 16519915.
    Citations: 12     Fields:    Translation:HumansCells
  80. Ndung'u T, Sepako E, McLane MF, Chand F, Bedi K, Gaseitsiwe S, Doualla-Bell F, Peter T, Thior I, Moyo SM, Gilbert PB, Novitsky VA, Essex M. HIV-1 subtype C in vitro growth and coreceptor utilization. Virology. 2006 Apr 10; 347(2):247-60. PMID: 16406460.
    Citations: 23     Fields:    Translation:Cells
  81. Gilbert PB, Novitsky V, Essex M. Covariability of selected amino acid positions for HIV type 1 subtypes C and B. AIDS Res Hum Retroviruses. 2005 Dec; 21(12):1016-30. PMID: 16379605.
    Citations: 16     Fields:    Translation:HumansCells
  82. Ndung'u T, Gaseitsiwe S, Sepako E, Doualla-Bell F, Peter T, Kim S, Thior I, Novitsky VA, Essex M. Major histocompatibility complex class II (HLA-DRB and -DQB) allele frequencies in Botswana: association with human immunodeficiency virus type 1 infection. Clin Diagn Lab Immunol. 2005 Sep; 12(9):1020-8. PMID: 16148166.
    Citations: 9     Fields:    Translation:HumansCells
  83. Bussmann H, Novitsky V, Wester W, Peter T, Masupu K, Gabaitiri L, Kim S, Gaseitsiwe S, Ndungú T, Marlink R, Thior I, Essex M. HIV-1 subtype C drug-resistance background among ARV-naive adults in Botswana. Antivir Chem Chemother. 2005; 16(2):103-15. PMID: 15889533.
    Citations: 7     Fields:    Translation:HumansCells
  84. McKinney DM, Skvoretz R, Livingston BD, Wilson CC, Anders M, Chesnut RW, Sette A, Essex M, Novitsky V, Newman MJ. Recognition of variant HIV-1 epitopes from diverse viral subtypes by vaccine-induced CTL. J Immunol. 2004 Aug 01; 173(3):1941-50. PMID: 15265928.
    Citations: 18     Fields:    Translation:HumansAnimalsCells
  85. Doualla-Bell F, Gaseitsiwe S, Ndungú T, Modukanele M, Peter T, Novitsky V, Ndwapi N, Tendani G, Avalos A, Wester W, Bussmann H, Cardiello P, Marlink R, Moffat H, Thior I, Wainberg MA, Essex M. Mutations and polymorphisms associated with antiretroviral drugs in HIV-1C-infected African patients. Antivir Chem Chemother. 2004 Jul; 15(4):189-200. PMID: 15457680.
    Citations: 8     Fields:    Translation:HumansCells
  86. Jones N, Agrawal D, Elrefaei M, Hanson A, Novitsky V, Wong JT, Cao H. Evaluation of antigen-specific responses using in vitro enriched T cells. J Immunol Methods. 2003 Mar 01; 274(1-2):139-47. PMID: 12609540.
    Citations: 20     Fields:    Translation:HumansCells
  87. Novitsky V, Gilbert P, Peter T, McLane MF, Gaolekwe S, Rybak N, Thior I, Ndung'u T, Marlink R, Lee TH, Essex M. Association between virus-specific T-cell responses and plasma viral load in human immunodeficiency virus type 1 subtype C infection. J Virol. 2003 Jan; 77(2):882-90. PMID: 12502804.
    Citations: 70     Fields:    Translation:HumansCells
  88. Novitsky V, Cao H, Rybak N, Gilbert P, McLane MF, Gaolekwe S, Peter T, Thior I, Ndung'u T, Marlink R, Lee TH, Essex M. Magnitude and frequency of cytotoxic T-lymphocyte responses: identification of immunodominant regions of human immunodeficiency virus type 1 subtype C. J Virol. 2002 Oct; 76(20):10155-68. PMID: 12239290.
    Citations: 48     Fields:    Translation:HumansCells
  89. Gaschen B, Taylor J, Yusim K, Foley B, Gao F, Lang D, Novitsky V, Haynes B, Hahn BH, Bhattacharya T, Korber B. Diversity considerations in HIV-1 vaccine selection. Science. 2002 Jun 28; 296(5577):2354-60. PMID: 12089434.
    Citations: 281     Fields:    Translation:HumansCells
  90. Novitsky V, Smith UR, Gilbert P, McLane MF, Chigwedere P, Williamson C, Ndung'u T, Klein I, Chang SY, Peter T, Thior I, Foley BT, Gaolekwe S, Rybak N, Gaseitsiwe S, Vannberg F, Marlink R, Lee TH, Essex M. Human immunodeficiency virus type 1 subtype C molecular phylogeny: consensus sequence for an AIDS vaccine design? J Virol. 2002 Jun; 76(11):5435-51. PMID: 11991972.
    Citations: 49     Fields:    Translation:HumansCells
  91. Ndung'u T, Lu Y, Renjifo B, Touzjian N, Kushner N, Pena-Cruz V, Novitsky VA, Lee TH, Essex M. Infectious simian/human immunodeficiency virus with human immunodeficiency virus type 1 subtype C from an African isolate: rhesus macaque model. J Virol. 2001 Dec; 75(23):11417-25. PMID: 11689623.
    Citations: 13     Fields:    Translation:HumansAnimalsCells
  92. Novitsky V, Rybak N, McLane MF, Gilbert P, Chigwedere P, Klein I, Gaolekwe S, Chang SY, Peter T, Thior I, Ndung'u T, Vannberg F, Foley BT, Marlink R, Lee TH, Essex M. Identification of human immunodeficiency virus type 1 subtype C Gag-, Tat-, Rev-, and Nef-specific elispot-based cytotoxic T-lymphocyte responses for AIDS vaccine design. J Virol. 2001 Oct; 75(19):9210-28. PMID: 11533184.
    Citations: 31     Fields:    Translation:HumansCells
  93. Novitsky V, Flores-Villanueva PO, Chigwedere P, Gaolekwe S, Bussman H, Sebetso G, Marlink R, Yunis EJ, Essex M. Identification of most frequent HLA class I antigen specificities in Botswana: relevance for HIV vaccine design. Hum Immunol. 2001 Feb; 62(2):146-56. PMID: 11182225.
    Citations: 21     Fields:    Translation:Humans
  94. Gilbert PB, Novitsky VA, Montano MA, Essex M. An efficient test for comparing sequence diversity between two populations. J Comput Biol. 2001; 8(2):123-39. PMID: 11454301.
    Citations: 1     Fields:    Translation:Cells
  95. Rivera-Morales LG, Novitsky VA, Trujillo JR, Lavalle-Montalvo C, Cano-Dominguez C, Ramos-Jimenez J, Jimenez-Rios E, Flores-Flores L, Lopez-Guillen P, Gilbert P, Vannberg F, Tamez-Guerra R, Rodriguez-Padilla C, Essex M. The molecular epidemiology of HIV type 1 of men in Mexico. AIDS Res Hum Retroviruses. 2001 Jan 01; 17(1):87-92. PMID: 11177387.
    Citations: 3     Fields:    Translation:HumansCells
  96. Ndung'u T, Renjifo B, Novitsky VA, McLane MF, Gaolekwe S, Essex M. Molecular cloning and biological characterization of full-length HIV-1 subtype C from Botswana. Virology. 2000 Dec 20; 278(2):390-9. PMID: 11118362.
    Citations: 20     Fields:    Translation:HumansAnimalsCells
  97. Novitsky VA, Gaolekwe S, McLane MF, Ndung'u TP, Foley BT, Vannberg F, Marlink R, Essex M. HIV type 1 A/J recombinant with a pronounced pol gene mosaicism. AIDS Res Hum Retroviruses. 2000 Jul 01; 16(10):1015-20. PMID: 10890363.
    Citations: 8     Fields:    Translation:HumansCells
  98. Montano MA, Nixon CP, Ndung'u T, Bussmann H, Novitsky VA, Dickman D, Essex M. Elevated tumor necrosis factor-alpha activation of human immunodeficiency virus type 1 subtype C in Southern Africa is associated with an NF-kappaB enhancer gain-of-function. J Infect Dis. 2000 Jan; 181(1):76-81. PMID: 10608753.
    Citations: 34     Fields:    Translation:HumansCells
  99. Novitsky VA, Montano MA, McLane MF, Renjifo B, Vannberg F, Foley BT, Ndung'u TP, Rahman M, Makhema MJ, Marlink R, Essex M. Molecular cloning and phylogenetic analysis of human immunodeficiency virus type 1 subtype C: a set of 23 full-length clones from Botswana. J Virol. 1999 May; 73(5):4427-32. PMID: 10196340.
    Citations: 42     Fields:    Translation:HumansCells
  100. Novitsky VA, Montano MA, Essex M. Molecular epidemiology of an HIV-1 subtype A subcluster among injection drug users in the Southern Ukraine. AIDS Res Hum Retroviruses. 1998 Aug 10; 14(12):1079-85. PMID: 9718124.
    Citations: 10     Fields:    Translation:HumansCells
  101. Montano MA, Novitsky VA, Blackard JT, Cho NL, Katzenstein DA, Essex M. Divergent transcriptional regulation among expanding human immunodeficiency virus type 1 subtypes. J Virol. 1997 Nov; 71(11):8657-65. PMID: 9343223.
    Citations: 45     Fields:    Translation:HumansCells
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Funded by the NIH/NCATS Clinical and Translational Science Award (CTSA) program, grant number UL1TR001102, and through institutional support from Harvard University, Harvard Medical School, Harvard T.H. Chan School of Public Health, Beth Israel Deaconess Medical Center, Boston Children's Hospital, Brigham and Women's Hospital, Massachusetts General Hospital and the Dana Farber Cancer Institute.