Harvard Catalyst Profiles

Contact, publication, and social network information about Harvard faculty and fellows.

Anne Esther Goldfeld, M.D.

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Other Positions
Title
Institution
Department
Title
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Mentoring
completed student projects
Immunological Susceptibility to Tuberculosis Infection
Full Time/Year Long, 09/01/98 - 06/30/99

Research
research activities and funding
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
Most Recent  |  List All
  1. R56AI165589 (GOLDFELD, ANNE) Jul 16, 2021 - Jun 30, 2022
    NIH
    Innate Immune Control of TB and HIV
    Role: Principal Investigator
  2. R56AI147950 (GOLDFELD, ANNE) Apr 1, 2020 - Mar 31, 2021
    NIH
    TB-induced immunity in HIV-infected and uninfected individuals
    Role: Principal Investigator
  3. R21AI151732 (GOLDFELD, ANNE) Mar 3, 2020 - Feb 28, 2022
    NIH
    Host factors and inhibition of Filoviruses
    Role: Principal Investigator
  4. R21AI127169 (GOLDFELD, ANNE) Jun 24, 2016 - Nov 30, 2018
    NIH
    Immunity to TB in highly immunosuppressed HIV-infected and uninfected individuals
    Role: Principal Investigator
  5. R01AI117929 (GOLDFELD, ANNE) Apr 1, 2016 - Mar 31, 2021
    NIH
    Immune control mechanisms of TB latency in the setting of HIV co-infection
    Role: Principal Investigator

Bibliographic
selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Junqueira C, Crespo Â, Ranjbar S, de Lacerda LB, Lewandrowski M, Ingber J, Parry B, Ravid S, Clark S, Schrimpf MR, Ho F, Beakes C, Margolin J, Russell N, Kays K, Boucau J, Das Adhikari U, Vora SM, Leger V, Gehrke L, Henderson LA, Janssen E, Kwon D, Sander C, Abraham J, Goldberg MB, Wu H, Mehta G, Bell S, Goldfeld AE, Filbin MR, Lieberman J. Fc?R-mediated SARS-CoV-2 infection of monocytes activates inflammation. Nature. 2022 06; 606(7914):576-584. PMID: 35385861.
    Citations: 108     Fields:    Translation:HumansCells
  2. Miorin L, Mire CE, Ranjbar S, Hume AJ, Huang J, Crossland NA, White KM, Laporte M, Kehrer T, Haridas V, Moreno E, Nambu A, Jangra S, Cupic A, Dejosez M, Abo KA, Tseng AE, Werder RB, Rathnasinghe R, Mutetwa T, Ramos I, de Aja JS, de Alba Rivas CG, Schotsaert M, Corley RB, Falvo JV, Fernandez-Sesma A, Kim C, Rossignol JF, Wilson AA, Zwaka T, Kotton DN, Mühlberger E, García-Sastre A, Goldfeld AE. The oral drug nitazoxanide restricts SARS-CoV-2 infection and attenuates disease pathogenesis in Syrian hamsters. bioRxiv. 2022 Feb 09. PMID: 35169796; PMCID: PMC8845418.
    Citations: 1     
  3. Junqueira C, Crespo Â, Ranjbar S, Lewandrowski M, Ingber J, de Lacerda LB, Parry B, Ravid S, Clark S, Ho F, Vora SM, Leger V, Beakes C, Margolin J, Russell N, Kays K, Gehrke L, Adhikari UD, Henderson L, Janssen E, Kwon D, Sander C, Abraham J, Filbin M, Goldberg MB, Wu H, Mehta G, Bell S, Goldfeld AE, Lieberman J. SARS-CoV-2 infects blood monocytes to activate NLRP3 and AIM2 inflammasomes, pyroptosis and cytokine release. Res Sq. 2021 Aug 11. PMID: 34401873; PMCID: PMC8366805.
    Citations:    
  4. Junqueira C, Crespo Â, Ranjbar S, Ingber J, Parry B, Ravid S, de Lacerda LB, Lewandrowski M, Clark S, Ho F, Vora SM, Leger V, Beakes C, Margolin J, Russell N, Gehrke L, Adhikari UD, Henderson L, Janssen E, Kwon D, Sander C, Abraham J, Filbin M, Goldberg MB, Wu H, Mehta G, Bell S, Goldfeld AE, Lieberman J. SARS-CoV-2 infects blood monocytes to activate NLRP3 and AIM2 inflammasomes, pyroptosis and cytokine release. medRxiv. 2021 Mar 08. PMID: 33758872; PMCID: PMC7987031.
    Citations: 2     
  5. Jasenosky LD, Nambu A, Tsytsykova AV, Ranjbar S, Haridas V, Kruidenier L, Tough DF, Goldfeld AE. Identification of a Distal Locus Enhancer Element That Controls Cell Type-Specific TNF and LTA Gene Expression in Human T Cells. J Immunol. 2020 11 01; 205(9):2479-2488. PMID: 32978279; PMCID: PMC7576113.
    Citations: 1     Fields:    Translation:HumansCells
  6. Blanc FX, Laureillard D, Goldfeld AE. Comment on: Effects of time of initiation of antiretroviral therapy in the treatment of patients with HIV/TB co-infection, by Chelkeba L. et al. Ann Med Surg (Lond). 2020 Sep; 57:22-23. PMID: 32714522; PMCID: PMC7371596.
    Citations:    
  7. Ranjbar S, Haridas V, Nambu A, Jasenosky LD, Sadhukhan S, Ebert TS, Hornung V, Cassell GH, Falvo JV, Goldfeld AE. Cytoplasmic RNA Sensor Pathways and Nitazoxanide Broadly Inhibit Intracellular Mycobacterium tuberculosis Growth. iScience. 2019 Dec 20; 22:299-313. PMID: 31805434.
    Citations: 11     
  8. Jasenosky LD, Cadena C, Mire CE, Borisevich V, Haridas V, Ranjbar S, Nambu A, Bavari S, Soloveva V, Sadukhan S, Cassell GH, Geisbert TW, Hur S, Goldfeld AE. The FDA-Approved Oral Drug Nitazoxanide Amplifies Host Antiviral Responses and Inhibits Ebola Virus. iScience. 2019 Sep 27; 19:1279-1290. PMID: 31402258.
    Citations: 51     
  9. Hurtado RM, Meressa D, Goldfeld AE. Treatment of drug-resistant tuberculosis among people living with HIV. Curr Opin HIV AIDS. 2018 11; 13(6):478-485. PMID: 30286039.
    Citations: 9     Fields:    Translation:HumansAnimalsCells
  10. Sam S, Shapiro AE, Sok T, Khann S, So R, Khem S, Chhun S, Noun S, Koy B, Sayouen PC, Im Sin C, Bunsieth H, Mao TE, Goldfeld AE. Initiation, scale-up and outcomes of the Cambodian National MDR-TB programme 2006-2016: hospital and community-based treatment through an NGO-NTP partnership. BMJ Open Respir Res. 2018; 5(1):e000256. PMID: 29955361; PMCID: PMC6018896.
    Citations: 5     
  11. Doan M, Vorobjev I, Rees P, Filby A, Wolkenhauer O, Goldfeld AE, Lieberman J, Barteneva N, Carpenter AE, Hennig H. Diagnostic Potential of Imaging Flow Cytometry. Trends Biotechnol. 2018 07; 36(7):649-652. PMID: 29395345.
    Citations: 30     Fields:    Translation:HumansCells
  12. Haridas V, Ranjbar S, Vorobjev IA, Goldfeld AE, Barteneva NS. Imaging flow cytometry analysis of intracellular pathogens. Methods. 2017 01 01; 112:91-104. PMID: 27642004.
    Citations: 17     Fields:    Translation:HumansAnimalsCells
  13. Meressa D, Hurtado RM, Andrews JR, Diro E, Abato K, Daniel T, Prasad P, Prasad R, Fekade B, Tedla Y, Yusuf H, Tadesse M, Tefera D, Ashenafi A, Desta G, Aderaye G, Olson K, Thim S, Goldfeld AE. Achieving high treatment success for multidrug-resistant TB in Africa: initiation and scale-up of MDR TB care in Ethiopia--an observational cohort study. Thorax. 2015 Dec; 70(12):1181-8. PMID: 26506854.
    Citations: 56     Fields:    Translation:Humans
  14. Ranjbar S, Haridas V, Jasenosky LD, Falvo JV, Goldfeld AE. A Role for IFITM Proteins in Restriction of Mycobacterium tuberculosis Infection. Cell Rep. 2015 Nov 03; 13(5):874-83. PMID: 26565900.
    Citations: 37     Fields:    Translation:HumansCells
  15. Jasenosky LD, Scriba TJ, Hanekom WA, Goldfeld AE. T cells and adaptive immunity to Mycobacterium tuberculosis in humans. Immunol Rev. 2015 Mar; 264(1):74-87. PMID: 25703553.
    Citations: 154     Fields:    Translation:HumansCells
  16. Haridas V, Pean P, Jasenosky LD, Madec Y, Laureillard D, Sok T, Sath S, Borand L, Marcy O, Chan S, Tsitsikov E, Delfraissy JF, Blanc FX, Goldfeld AE. TB-IRIS, T-cell activation, and remodeling of the T-cell compartment in highly immunosuppressed HIV-infected patients with TB. AIDS. 2015 Jan 28; 29(3):263-73. PMID: 25486415; PMCID: PMC4649949.
    Citations: 17     Fields:    Translation:HumansCells
  17. Chow NA, Jasenosky LD, Goldfeld AE. A distal locus element mediates IFN-? priming of lipopolysaccharide-stimulated TNF gene expression. Cell Rep. 2014 Dec 11; 9(5):1718-1728. PMID: 25482561; PMCID: PMC4268019.
    Citations: 9     Fields:    Translation:HumansCells
  18. Marcy O, Laureillard D, Madec Y, Chan S, Mayaud C, Borand L, Prak N, Kim C, Lak KK, Hak C, Dim B, Sok T, Delfraissy JF, Goldfeld AE, Blanc FX. Causes and determinants of mortality in HIV-infected adults with tuberculosis: an analysis from the CAMELIA ANRS 1295-CIPRA KH001 randomized trial. Clin Infect Dis. 2014 Aug 01; 59(3):435-45. PMID: 24759827.
    Citations: 23     Fields:    Translation:Humans
  19. Borand L, Madec Y, Laureillard D, Chou M, Marcy O, Pheng P, Prak N, Kim C, Lak KK, Hak C, Dim B, Nerrienet E, Fontanet A, Sok T, Goldfeld AE, Blanc FX, Taburet AM. Plasma concentrations, efficacy and safety of efavirenz in HIV-infected adults treated for tuberculosis in Cambodia (ANRS 1295-CIPRA KH001 CAMELIA trial). PLoS One. 2014; 9(3):e90350. PMID: 24608960.
    Citations: 8     Fields:    Translation:HumansCells
  20. Laureillard D, Marcy O, Madec Y, Chea S, Chan S, Borand L, Fernandez M, Prak N, Kim C, Dim B, Nerrienet E, Sok T, Delfraissy JF, Goldfeld AE, Blanc FX. Paradoxical tuberculosis-associated immune reconstitution inflammatory syndrome after early initiation of antiretroviral therapy in a randomized clinical trial. AIDS. 2013 Oct 23; 27(16):2577-86. PMID: 24096631.
    Citations: 40     Fields:    Translation:Humans
  21. Falvo JV, Jasenosky LD, Kruidenier L, Goldfeld AE. Epigenetic control of cytokine gene expression: regulation of the TNF/LT locus and T helper cell differentiation. Adv Immunol. 2013; 118:37-128. PMID: 23683942.
    Citations: 26     Fields:    Translation:HumansAnimalsCells
  22. Borand L, Laureillard D, Madec Y, Chou M, Pheng P, Marcy O, Sok T, Goldfeld AE, Taburet AM, Blanc FX. Plasma concentrations of efavirenz with a 600 mg standard dose in Cambodian HIV-infected adults treated for tuberculosis with a body weight above 50 kg. Antivir Ther. 2013; 18(3):419-23. PMID: 23237982.
    Citations: 3     Fields:    Translation:Humans
  23. Via LE, Tsytsykova AV, Rajsbaum R, Falvo JV, Goldfeld AE. The transcription factor NFATp plays a key role in susceptibility to TB in mice. PLoS One. 2012; 7(7):e41427. PMID: 22844476.
    Citations: 4     Fields:    Translation:AnimalsCells
  24. Ranjbar S, Jasenosky LD, Chow N, Goldfeld AE. Regulation of Mycobacterium tuberculosis-dependent HIV-1 transcription reveals a new role for NFAT5 in the toll-like receptor pathway. PLoS Pathog. 2012; 8(4):e1002620. PMID: 22496647.
    Citations: 25     Fields:    Translation:HumansCells
  25. Biglione S, Tsytsykova AV, Goldfeld AE. Monocyte-specific accessibility of a matrix attachment region in the tumor necrosis factor locus. J Biol Chem. 2011 Dec 23; 286(51):44126-44133. PMID: 22027829.
    Citations: 3     Fields:    Translation:HumansCells
  26. Blanc FX, Sok T, Laureillard D, Borand L, Rekacewicz C, Nerrienet E, Madec Y, Marcy O, Chan S, Prak N, Kim C, Lak KK, Hak C, Dim B, Sin CI, Sun S, Guillard B, Sar B, Vong S, Fernandez M, Fox L, Delfraissy JF, Goldfeld AE. Earlier versus later start of antiretroviral therapy in HIV-infected adults with tuberculosis. N Engl J Med. 2011 Oct 20; 365(16):1471-81. PMID: 22010913; PMCID: PMC4879711.
    Citations: 280     Fields:    Translation:Humans
  27. Kovalenko EI, Ranjbar S, Jasenosky LD, Goldfeld AE, Vorobjev IA, Barteneva NS. The use of HaloTag-based technology in flow and laser scanning cytometry analysis of live and fixed cells. BMC Res Notes. 2011 Sep 09; 4:340. PMID: 21906296.
    Citations: 7     Fields:    
  28. Falvo JV, Ranjbar S, Jasenosky LD, Goldfeld AE. Arc of a vicious circle: pathways activated by Mycobacterium tuberculosis that target the HIV-1 long terminal repeat. Am J Respir Cell Mol Biol. 2011 Dec; 45(6):1116-24. PMID: 21852682.
    Citations: 15     Fields:    Translation:HumansAnimalsCells
  29. Falvo JV, Tsytsykova AV, Goldfeld AE. Transcriptional control of the TNF gene. Curr Dir Autoimmun. 2010; 11:27-60. PMID: 20173386.
    Citations: 109     Fields:    Translation:HumansAnimalsCells
  30. Ranjbar S, Boshoff HI, Mulder A, Siddiqi N, Rubin EJ, Goldfeld AE. HIV-1 replication is differentially regulated by distinct clinical strains of Mycobacterium tuberculosis. PLoS One. 2009 Jul 01; 4(7):e6116. PMID: 19568431.
    Citations: 20     Fields:    Translation:HumansCells
  31. Falvo JV, Lin CH, Tsytsykova AV, Hwang PK, Thanos D, Goldfeld AE, Maniatis T. A dimer-specific function of the transcription factor NFATp. Proc Natl Acad Sci U S A. 2008 Dec 16; 105(50):19637-42. PMID: 19060202.
    Citations: 16     Fields:    Translation:Cells
  32. Tsytsykova AV, Rajsbaum R, Falvo JV, Ligeiro F, Neely SR, Goldfeld AE. Activation-dependent intrachromosomal interactions formed by the TNF gene promoter and two distal enhancers. Proc Natl Acad Sci U S A. 2007 Oct 23; 104(43):16850-5. PMID: 17940009.
    Citations: 44     Fields:    Translation:AnimalsCells
  33. Blanc FX, Havlir DV, Onyebujoh PC, Thim S, Goldfeld AE, Delfraissy JF. Treatment strategies for HIV-infected patients with tuberculosis: ongoing and planned clinical trials. J Infect Dis. 2007 Aug 15; 196 Suppl 1:S46-51. PMID: 17624825.
    Citations: 17     Fields:    Translation:HumansCells
  34. Baena A, Mootnick AR, Falvo JV, Tsytskova AV, Ligeiro F, Diop OM, Brieva C, Gagneux P, O'Brien SJ, Ryder OA, Goldfeld AE. Primate TNF promoters reveal markers of phylogeny and evolution of innate immunity. PLoS One. 2007 Jul 18; 2(7):e621. PMID: 17637837.
    Citations: 16     Fields:    Translation:HumansAnimalsCells
  35. Goldfeld A, Ellner JJ. Pathogenesis and management of HIV/TB co-infection in Asia. Tuberculosis (Edinb). 2007 Aug; 87 Suppl 1:S26-30. PMID: 17606407.
    Citations: 2     Fields:    Translation:HumansCells
  36. Tsytsykova AV, Falvo JV, Schmidt-Supprian M, Courtois G, Thanos D, Goldfeld AE. Post-induction, stimulus-specific regulation of tumor necrosis factor mRNA expression. J Biol Chem. 2007 Apr 20; 282(16):11629-38. PMID: 17303559.
    Citations: 18     Fields:    Translation:HumansAnimalsCells
  37. Ranjbar S, Tsytsykova AV, Lee SK, Rajsbaum R, Falvo JV, Lieberman J, Shankar P, Goldfeld AE. NFAT5 regulates HIV-1 in primary monocytes via a highly conserved long terminal repeat site. PLoS Pathog. 2006 Dec; 2(12):e130. PMID: 17173480; PMCID: PMC1698943.
    Citations: 29     Fields:    Translation:HumansCells
  38. Ranjbar S, Rajsbaum R, Goldfeld AE. Transactivator of transcription from HIV type 1 subtype E selectively inhibits TNF gene expression via interference with chromatin remodeling of the TNF locus. J Immunol. 2006 Apr 01; 176(7):4182-90. PMID: 16547255.
    Citations: 16     Fields:    Translation:HumansCells
  39. Ward V, Hennig BJ, Hirai K, Tahara H, Tamori A, Dawes R, Saito M, Bangham C, Stephens H, Goldfeld AE, Kunachiwa W, Leetrakool N, Hopkin J, Dunstan S, Hill A, Bodmer W, Beverley PC, Tchilian EZ. Geographical distribution and disease associations of the CD45 exon 6 138G variant. Immunogenetics. 2006 Apr; 58(2-3):235-9. PMID: 16538473.
    Citations: 2     Fields:    Translation:Humans
  40. Delgado JC, Baena A, Thim S, Goldfeld AE. Aspartic acid homozygosity at codon 57 of HLA-DQ beta is associated with susceptibility to pulmonary tuberculosis in Cambodia. J Immunol. 2006 Jan 15; 176(2):1090-7. PMID: 16393997.
    Citations: 19     Fields:    Translation:HumansCells
  41. Saraiva M, Christensen JR, Tsytsykova AV, Goldfeld AE, Ley SC, Kioussis D, O'Garra A. Identification of a macrophage-specific chromatin signature in the IL-10 locus. J Immunol. 2005 Jul 15; 175(2):1041-6. PMID: 16002704.
    Citations: 50     Fields:    Translation:HumansAnimalsCells
  42. Esensten JH, Tsytsykova AV, Lopez-Rodriguez C, Ligeiro FA, Rao A, Goldfeld AE. NFAT5 binds to the TNF promoter distinctly from NFATp, c, 3 and 4, and activates TNF transcription during hypertonic stress alone. Nucleic Acids Res. 2005; 33(12):3845-54. PMID: 16027109; PMCID: PMC1175021.
    Citations: 35     Fields:    Translation:AnimalsCells
  43. Lee SK, Dykxhoorn DM, Kumar P, Ranjbar S, Song E, Maliszewski LE, François-Bongarçon V, Goldfeld A, Swamy NM, Lieberman J, Shankar P. Lentiviral delivery of short hairpin RNAs protects CD4 T cells from multiple clades and primary isolates of HIV. Blood. 2005 Aug 01; 106(3):818-26. PMID: 15831707; PMCID: PMC1895148.
    Citations: 52     Fields:    Translation:HumansCells
  44. O'Garra A, Vieira PL, Vieira P, Goldfeld AE. IL-10-producing and naturally occurring CD4+ Tregs: limiting collateral damage. J Clin Invest. 2004 Nov; 114(10):1372-8. PMID: 15545984; PMCID: PMC525746.
    Citations: 199     Fields:    Translation:HumansAnimalsCells
  45. Thim S, Sath S, Sina M, Tsai EY, Delgado JC, Shapiro AE, Barry CE, Glaziou P, Goldfeld AE. A community-based tuberculosis program in Cambodia. JAMA. 2004 Aug 04; 292(5):566-8. PMID: 15292081.
    Citations: 10     Fields:    Translation:Humans
  46. Delgado JC, Quiñones-Berrocal J, Thim S, Miranda LF, Goldfeld AE. Diagnostic and clinical implications of response to tuberculin in two ethnically distinct populations from Peru and Cambodia. Int J Tuberc Lung Dis. 2004 Aug; 8(8):982-7. PMID: 15305481.
    Citations: 1     Fields:    Translation:Humans
  47. Ranjbar S, Ly N, Thim S, Reynes JM, Goldfeld AE. Mycobacterium tuberculosis recall antigens suppress HIV-1 replication in anergic donor cells via CD8+ T cell expansion and increased IL-10 levels. J Immunol. 2004 Feb 01; 172(3):1953-9. PMID: 14734781.
    Citations: 8     Fields:    Translation:Cells
  48. Goldfeld AE. Genetic susceptibility to pulmonary tuberculosis in Cambodia. Tuberculosis (Edinb). 2004; 84(1-2):76-81. PMID: 14670348.
    Citations: 5     Fields:    Translation:Humans
  49. Barthel R, Goldfeld AE. T cell-specific expression of the human TNF-alpha gene involves a functional and highly conserved chromatin signature in intron 3. J Immunol. 2003 Oct 01; 171(7):3612-9. PMID: 14500658.
    Citations: 15     Fields:    Translation:HumansAnimalsCells
  50. Delgado JC, Leung JY, Baena A, Clavijo OP, Vittinghoff E, Buchbinder S, Wolinsky S, Addo M, Walker BD, Yunis EJ, Goldfeld AE. The -1030/-862-linked TNF promoter single-nucleotide polymorphisms are associated with the inability to control HIV-1 viremia. Immunogenetics. 2003 Oct; 55(7):497-501. PMID: 14517700.
    Citations: 5     Fields:    Translation:HumansCells
  51. Barthel R, Tsytsykova AV, Barczak AK, Tsai EY, Dascher CC, Brenner MB, Goldfeld AE. Regulation of tumor necrosis factor alpha gene expression by mycobacteria involves the assembly of a unique enhanceosome dependent on the coactivator proteins CBP/p300. Mol Cell Biol. 2003 Jan; 23(2):526-33. PMID: 12509451.
    Citations: 41     Fields:    Translation:HumansAnimalsCells
  52. Baena A, Leung JY, Sullivan AD, Landires I, Vasquez-Luna N, Quiñones-Berrocal J, Fraser PA, Uko GP, Delgado JC, Clavijo OP, Thim S, Meshnick SR, Nyirenda T, Yunis EJ, Goldfeld AE. TNF-alpha promoter single nucleotide polymorphisms are markers of human ancestry. Genes Immun. 2002 Dec; 3(8):482-7. PMID: 12486607.
    Citations: 21     Fields:    Translation:HumansCells
  53. Delgado JC, Baena A, Thim S, Goldfeld AE. Ethnic-specific genetic associations with pulmonary tuberculosis. J Infect Dis. 2002 Nov 15; 186(10):1463-8. PMID: 12404162.
    Citations: 81     Fields:    Translation:Humans
  54. Delgado JC, Tsai EY, Thim S, Baena A, Boussiotis VA, Reynes JM, Sath S, Grosjean P, Yunis EJ, Goldfeld AE. Antigen-specific and persistent tuberculin anergy in a cohort of pulmonary tuberculosis patients from rural Cambodia. Proc Natl Acad Sci U S A. 2002 May 28; 99(11):7576-81. PMID: 12032325; PMCID: PMC124289.
    Citations: 35     Fields:    Translation:HumansCells
  55. Tsytsykova AV, Goldfeld AE. Inducer-specific enhanceosome formation controls tumor necrosis factor alpha gene expression in T lymphocytes. Mol Cell Biol. 2002 Apr; 22(8):2620-31. PMID: 11909956.
    Citations: 37     Fields:    Translation:HumansCells
  56. Flores-Villanueva PO, Yunis EJ, Delgado JC, Vittinghoff E, Buchbinder S, Leung JY, Uglialoro AM, Clavijo OP, Rosenberg ES, Kalams SA, Braun JD, Boswell SL, Walker BD, Goldfeld AE. Control of HIV-1 viremia and protection from AIDS are associated with HLA-Bw4 homozygosity. Proc Natl Acad Sci U S A. 2001 Apr 24; 98(9):5140-5. PMID: 11309482; PMCID: PMC33177.
    Citations: 101     Fields:    Translation:HumansCells
  57. Goldfeld AE, Leung JY, Sawyer SA, Hartl DL. Post-genomics and the neutral theory: variation and conservation in the tumor necrosis factor-alpha promoter. Gene. 2000 Dec 30; 261(1):19-25. PMID: 11164033.
    Citations: 8     Fields:    Translation:HumansAnimalsCells
  58. Tsytsykova AV, Goldfeld AE. Nuclear factor of activated T cells transcription factor NFATp controls superantigen-induced lethal shock. J Exp Med. 2000 Aug 21; 192(4):581-6. PMID: 10952728; PMCID: PMC2193238.
    Citations: 17     Fields:    Translation:HumansAnimalsCells
  59. Tsai EY, Falvo JV, Tsytsykova AV, Barczak AK, Reimold AM, Glimcher LH, Fenton MJ, Gordon DC, Dunn IF, Goldfeld AE. A lipopolysaccharide-specific enhancer complex involving Ets, Elk-1, Sp1, and CREB binding protein and p300 is recruited to the tumor necrosis factor alpha promoter in vivo. Mol Cell Biol. 2000 Aug; 20(16):6084-94. PMID: 10913190.
    Citations: 99     Fields:    Translation:AnimalsCells
  60. Leung JY, McKenzie FE, Uglialoro AM, Flores-Villanueva PO, Sorkin BC, Yunis EJ, Hartl DL, Goldfeld AE. Identification of phylogenetic footprints in primate tumor necrosis factor-alpha promoters. Proc Natl Acad Sci U S A. 2000 Jun 06; 97(12):6614-8. PMID: 10841560; PMCID: PMC18676.
    Citations: 15     Fields:    Translation:HumansAnimalsCells
  61. Boussiotis VA, Tsai EY, Yunis EJ, Thim S, Delgado JC, Dascher CC, Berezovskaya A, Rousset D, Reynes JM, Goldfeld AE. IL-10-producing T cells suppress immune responses in anergic tuberculosis patients. J Clin Invest. 2000 May; 105(9):1317-25. PMID: 10792007; PMCID: PMC315449.
    Citations: 141     Fields:    Translation:HumansCells
  62. Falvo JV, Brinkman BM, Tsytsykova AV, Tsai EY, Yao TP, Kung AL, Goldfeld AE. A stimulus-specific role for CREB-binding protein (CBP) in T cell receptor-activated tumor necrosis factor alpha gene expression. Proc Natl Acad Sci U S A. 2000 Apr 11; 97(8):3925-9. PMID: 10760264; PMCID: PMC18118.
    Citations: 28     Fields:    Translation:HumansAnimalsCells
  63. Falvo JV, Uglialoro AM, Brinkman BM, Merika M, Parekh BS, Tsai EY, King HC, Morielli AD, Peralta EG, Maniatis T, Thanos D, Goldfeld AE. Stimulus-specific assembly of enhancer complexes on the tumor necrosis factor alpha gene promoter. Mol Cell Biol. 2000 Mar; 20(6):2239-47. PMID: 10688670.
    Citations: 62     Fields:    Translation:HumansCells
  64. Brinkman BM, Telliez JB, Schievella AR, Lin LL, Goldfeld AE. Engagement of tumor necrosis factor (TNF) receptor 1 leads to ATF-2- and p38 mitogen-activated protein kinase-dependent TNF-alpha gene expression. J Biol Chem. 1999 Oct 22; 274(43):30882-6. PMID: 10521481.
    Citations: 27     Fields:    Translation:HumansAnimalsCells
  65. Marshall WL, Brinkman BM, Ambrose CM, Pesavento PA, Uglialoro AM, Teng E, Finberg RW, Browning JL, Goldfeld AE. Signaling through the lymphotoxin-beta receptor stimulates HIV-1 replication alone and in cooperation with soluble or membrane-bound TNF-alpha. J Immunol. 1999 May 15; 162(10):6016-23. PMID: 10229841.
    Citations: 8     Fields:    Translation:HumansCells
  66. Uglialoro AM, Turbay D, Pesavento PA, Delgado JC, McKenzie FE, Gribben JG, Hartl D, Yunis EJ, Goldfeld AE. Identification of three new single nucleotide polymorphisms in the human tumor necrosis factor-alpha gene promoter. Tissue Antigens. 1998 Oct; 52(4):359-67. PMID: 9820599; PMCID: PMC2518982.
    Citations: 58     Fields:    Translation:HumansAnimalsCells
  67. Hata D, Kawakami Y, Inagaki N, Lantz CS, Kitamura T, Khan WN, Maeda-Yamamoto M, Miura T, Han W, Hartman SE, Yao L, Nagai H, Goldfeld AE, Alt FW, Galli SJ, Witte ON, Kawakami T. Involvement of Bruton's tyrosine kinase in FcepsilonRI-dependent mast cell degranulation and cytokine production. J Exp Med. 1998 Apr 20; 187(8):1235-47. PMID: 9547335; PMCID: PMC2212237.
    Citations: 97     Fields:    Translation:AnimalsCells
  68. Goldfeld AE, Delgado JC, Thim S, Bozon MV, Uglialoro AM, Turbay D, Cohen C, Yunis EJ. Association of an HLA-DQ allele with clinical tuberculosis. JAMA. 1998 Jan 21; 279(3):226-8. PMID: 9438744.
    Citations: 44     Fields:    Translation:HumansCells
  69. Goldfeld AE, Tsai EY. TNF-alpha and genetic susceptibility to parasitic disease. Exp Parasitol. 1996 Nov; 84(2):300-3. PMID: 8932781.
    Citations: 2     Fields:    Translation:HumansAnimalsCells
  70. Tsai EY, Yie J, Thanos D, Goldfeld AE. Cell-type-specific regulation of the human tumor necrosis factor alpha gene in B cells and T cells by NFATp and ATF-2/JUN. Mol Cell Biol. 1996 Oct; 16(10):5232-44. PMID: 8816436.
    Citations: 65     Fields:    Translation:HumansAnimalsCells
  71. Tsai EY, Jain J, Pesavento PA, Rao A, Goldfeld AE. Tumor necrosis factor alpha gene regulation in activated T cells involves ATF-2/Jun and NFATp. Mol Cell Biol. 1996 Feb; 16(2):459-67. PMID: 8552071.
    Citations: 78     Fields:    Translation:HumansAnimalsCells
  72. Trede NS, Tsytsykova AV, Chatila T, Goldfeld AE, Geha RS. Transcriptional activation of the human TNF-alpha promoter by superantigen in human monocytic cells: role of NF-kappa B. J Immunol. 1995 Jul 15; 155(2):902-8. PMID: 7608567.
    Citations: 48     Fields:    Translation:HumansCells
  73. Goldfeld AE, Liu P, Liu S, Flemington EK, Strominger JL, Speck SH. Cyclosporin A and FK506 block induction of the Epstein-Barr virus lytic cycle by anti-immunoglobulin. Virology. 1995 May 10; 209(1):225-9. PMID: 7538254.
    Citations: 17     Fields:    Translation:HumansCells
  74. McCaffrey PG, Goldfeld AE, Rao A. The role of NFATp in cyclosporin A-sensitive tumor necrosis factor-alpha gene transcription. J Biol Chem. 1994 Dec 02; 269(48):30445-50. PMID: 7982959.
    Citations: 47     Fields:    Translation:HumansCells
  75. Goldfeld AE, Tsai E, Kincaid R, Belshaw PJ, Schrieber SL, Strominger JL, Rao A. Calcineurin mediates human tumor necrosis factor alpha gene induction in stimulated T and B cells. J Exp Med. 1994 Aug 01; 180(2):763-8. PMID: 8046352; PMCID: PMC2191603.
    Citations: 25     Fields:    Translation:HumansCells
  76. Boussiotis VA, Nadler LM, Strominger JL, Goldfeld AE. Tumor necrosis factor alpha is an autocrine growth factor for normal human B cells. Proc Natl Acad Sci U S A. 1994 Jul 19; 91(15):7007-11. PMID: 7518925; PMCID: PMC44327.
    Citations: 41     Fields:    Translation:HumansCells
  77. Goldfeld AE, McCaffrey PG, Strominger JL, Rao A. Identification of a novel cyclosporin-sensitive element in the human tumor necrosis factor alpha gene promoter. J Exp Med. 1993 Oct 01; 178(4):1365-79. PMID: 8376940; PMCID: PMC2191206.
    Citations: 62     Fields:    Translation:HumansCells
  78. Goldfeld AE, Flemington EK, Boussiotis VA, Theodos CM, Titus RG, Strominger JL, Speck SH. Transcription of the tumor necrosis factor alpha gene is rapidly induced by anti-immunoglobulin and blocked by cyclosporin A and FK506 in human B cells. Proc Natl Acad Sci U S A. 1992 Dec 15; 89(24):12198-201. PMID: 1281550; PMCID: PMC50726.
    Citations: 19     Fields:    Translation:HumansCells
  79. Flemington EK, Goldfeld AE, Speck SH. Efficient transcription of the Epstein-Barr virus immediate-early BZLF1 and BRLF1 genes requires protein synthesis. J Virol. 1991 Dec; 65(12):7073-7. PMID: 1658397; PMCID: PMC250835.
    Citations: 51     Fields:    Translation:HumansCells
  80. Goldfeld AE, Strominger JL, Doyle C. Human tumor necrosis factor alpha gene regulation in phorbol ester stimulated T and B cell lines. J Exp Med. 1991 Jul 01; 174(1):73-81. PMID: 2056282; PMCID: PMC2118869.
    Citations: 40     Fields:    Translation:HumansCells
  81. Goldfeld AE, Birch-Limberger K, Schooley RT, Walker BD. HIV-1 infection does not induce tumor necrosis factor-alpha or interferon-beta gene transcription. J Acquir Immune Defic Syndr (1988). 1991; 4(1):41-7. PMID: 1845771.
    Citations: 16     Fields:    Translation:HumansCells
  82. Goldfeld AE, Doyle C, Maniatis T. Human tumor necrosis factor alpha gene regulation by virus and lipopolysaccharide. Proc Natl Acad Sci U S A. 1990 Dec; 87(24):9769-73. PMID: 2263628; PMCID: PMC55255.
    Citations: 78     Fields:    Translation:HumansAnimalsCells
  83. Goldfeld AE, Maniatis T. Coordinate viral induction of tumor necrosis factor alpha and interferon beta in human B cells and monocytes. Proc Natl Acad Sci U S A. 1989 Mar; 86(5):1490-4. PMID: 2537976; PMCID: PMC286722.
    Citations: 37     Fields:    Translation:HumansCells
  84. Goldfeld AE, Mollica RF, Pesavento BH, Faraone SV. The physical and psychological sequelae of torture. Symptomatology and diagnosis. JAMA. 1988 May 13; 259(18):2725-9. PMID: 3282086.
    Citations: 20     Fields:    Translation:Humans
  85. Goldfeld AE. Murder in Guatemala. N Engl J Med. 1984 May 03; 310(18):1186. PMID: 6369138.
    Citations:    Fields:    Translation:Humans
  86. Goldfeld AE, Firestone GL, Shaw PA, Gluecksohn-Waelsch S. Recessive lethal deletion on mouse chromosome 7 affects glucocorticoid receptor binding activities. Proc Natl Acad Sci U S A. 1983 Mar; 80(5):1431-4. PMID: 6572398; PMCID: PMC393611.
    Citations: 10     Fields:    Translation:Animals
  87. Goldfeld AE, Rubin CS, Siegel TW, Shaw PA, Schiffer SG, Gluecksohn-Waelsch S. Genetic control of insulin receptors. Proc Natl Acad Sci U S A. 1981 Oct; 78(10):6359-61. PMID: 7031649; PMCID: PMC349038.
    Citations: 4     Fields:    Translation:AnimalsCells
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