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Leonid Peshkin, Ph.D.

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Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Jonas-Closs RA, Peshkin L. Effective Rapid Blood Perfusion in Xenopus. bioRxiv. 2023 Feb 03. PMID: 36778320; PMCID: PMC9915651.
  2. Gruver S, Rata S, Peshkin L, Kirschner MW. Identification of kinases activated by multiple pro-angiogenic growth factors. Front Pharmacol. 2022; 13:1022722. PMID: 36686695; PMCID: PMC9847502.
  3. Zhang Y, Rabinovsky R, Wei Z, El Fatimy R, Deforzh E, Luan B, Peshkin L, Uhlmann EJ, Krichevsky AM. Secreted PGK1 and IGFBP2 contribute to the bystander effect of miR-10b gene editing in glioma. Mol Ther Nucleic Acids. 2023 Mar 14; 31:265-275. PMID: 36700043; PMCID: PMC9852814.
  4. Anderson CE, Malek MC, Jonas-Closs RA, Cho Y, Peshkin L, Kirschner MW, Yampolsky LY. Inverse Lansing Effect: Maternal Age and Provisioning Affecting Daughters' Longevity and Male Offspring Production. Am Nat. 2022 11; 200(5):704-721. PMID: 36260845.
    Citations:    Fields:    Translation:Animals
  5. Shindyapina AV, Cho Y, Kaya A, Tyshkovskiy A, Castro JP, Deik A, Gordevicius J, Poganik JR, Clish CB, Horvath S, Peshkin L, Gladyshev VN. Rapamycin treatment during development extends life span and health span of male mice and Daphnia magna. Sci Adv. 2022 09 16; 8(37):eabo5482. PMID: 36112674; PMCID: PMC9481125.
    Citations: 2     Fields:    Translation:Animals
  6. Gorbsky GJ, Daum JR, Sapkota H, Summala K, Yoshida H, Georgescu C, Wren JD, Peshkin L, Horb ME. Developing immortal cell lines from Xenopus embryos, four novel cell lines derived from Xenopus tropicalis. Open Biol. 2022 07; 12(7):220089. PMID: 35857907; PMCID: PMC9256088.
    Citations:    Fields:    Translation:AnimalsCells
  7. Popadin K, Gunbin K, Peshkin L, Annis S, Fleischmann Z, Franco M, Kraytsberg Y, Markuzon N, Ackermann RR, Khrapko K. Mitochondrial Pseudogenes Suggest Repeated Inter-Species Hybridization among Direct Human Ancestors. Genes (Basel). 2022 05 01; 13(5). PMID: 35627195; PMCID: PMC9140377.
    Citations:    Fields:    Translation:HumansAnimalsCells
  8. Cho Y, Jonas-Closs RA, Yampolsky LY, Kirschner MW, Peshkin L. Intelligent high-throughput intervention testing platform in Daphnia. Aging Cell. 2022 03; 21(3):e13571. PMID: 35195332; PMCID: PMC8920439.
    Citations: 1     Fields:    Translation:Animals
  9. Anderson CE, Ekwudo MN, Jonas-Closs RA, Cho Y, Peshkin L, Kirschner MW, Yampolsky LY. Lack of age-related respiratory changes in Daphnia. Biogerontology. 2022 02; 23(1):85-97. PMID: 34989913.
    Citations:    Fields:    Translation:Animals
  10. Liu X, Oh S, Peshkin L, Kirschner MW. Computationally enhanced quantitative phase microscopy reveals autonomous oscillations in mammalian cell growth. Proc Natl Acad Sci U S A. 2020 11 03; 117(44):27388-27399. PMID: 33087574.
    Citations: 5     Fields:    Translation:HumansCells
  11. Peshkin L, Gupta M, Ryazanova L, Wühr M. Bayesian Confidence Intervals for Multiplexed Proteomics Integrate Ion-statistics with Peptide Quantification Concordance. Mol Cell Proteomics. 2019 Oct; 18(10):2108-2120. PMID: 33451482.
  12. Peshkin L, Kirschner MW. A cell type annotation Jamboree-Revival of ? communal science forum. Genesis. 2020 09; 58(9):e23383. PMID: 32584459.
    Citations: 1     Fields:    Translation:Animals
  13. Mugahid D, Kalocsay M, Liu X, Gruver JS, Peshkin L, Kirschner MW. YAP regulates cell size and growth dynamics via non-cell autonomous mediators. Elife. 2020 Jan 09; 9. PMID: 31913124; PMCID: PMC6989120.
    Citations: 9     Fields:    Translation:HumansCells
  14. Peshkin L, Boukhali M, Haas W, Kirschner MW, Yampolsky LY. Quantitative Proteomics Reveals Remodeling of Protein Repertoire Across Life Phases of Daphnia pulex. Proteomics. 2019 12; 19(24):e1900155. PMID: 31697011.
    Citations:    Fields:    Translation:Animals
  15. Korotkova DD, Lyubetsky VA, Ivanova AS, Rubanov LI, Seliverstov AV, Zverkov OA, Martynova NY, Nesterenko AM, Tereshina MB, Peshkin L, Zaraisky AG. Bioinformatics Screening of Genes Specific for Well-Regenerating Vertebrates Reveals c-answer, a Regulator of Brain Development and Regeneration. Cell Rep. 2019 10 22; 29(4):1027-1040.e6. PMID: 31644900.
    Citations: 6     Fields:    Translation:AnimalsCells
  16. Peshkin L, Gupta M, Ryazanova L, Wühr M. Bayesian Confidence Intervals for Multiplexed Proteomics Integrate Ion-statistics with Peptide Quantification Concordance. Mol Cell Proteomics. 2019 10; 18(10):2108-2120. PMID: 31311848.
    Citations: 9     Fields:    Translation:HumansCells
  17. Briggs JA, Weinreb C, Wagner DE, Megason S, Peshkin L, Kirschner MW, Klein AM. The dynamics of gene expression in vertebrate embryogenesis at single-cell resolution. Science. 2018 06 01; 360(6392). PMID: 29700227.
    Citations: 161     Fields:    Translation:AnimalsCells
  18. Presler M, Van Itallie E, Klein AM, Kunz R, Coughlin ML, Peshkin L, Gygi SP, Wühr M, Kirschner MW. Proteomics of phosphorylation and protein dynamics during fertilization and meiotic exit in the Xenopus egg. Proc Natl Acad Sci U S A. 2017 12 12; 114(50):E10838-E10847. PMID: 29183978; PMCID: PMC5740657.
    Citations: 21     Fields:    Translation:AnimalsCells
  19. Gunbin K, Peshkin L, Popadin K, Annis S, Ackermann RR, Khrapko K. Data on the time of integration of the human mitochondrial pseudogenes (NUMTs) into the nuclear genome. Data Brief. 2017 Aug; 13:536-544. PMID: 28702491.
    Citations: 2     
  20. Savova V, Pearl EJ, Boke E, Nag A, Adzhubei I, Horb ME, Peshkin L. Transcriptomic insights into genetic diversity of protein-coding genes in X. laevis. Dev Biol. 2017 04 15; 424(2):181-188. PMID: 28283406; PMCID: PMC5405699.
    Citations: 5     Fields:    Translation:AnimalsCells
  21. Bryant DM, Johnson K, DiTommaso T, Tickle T, Couger MB, Payzin-Dogru D, Lee TJ, Leigh ND, Kuo TH, Davis FG, Bateman J, Bryant S, Guzikowski AR, Tsai SL, Coyne S, Ye WW, Freeman RM, Peshkin L, Tabin CJ, Regev A, Haas BJ, Whited JL. A Tissue-Mapped Axolotl De Novo Transcriptome Enables Identification of Limb Regeneration Factors. Cell Rep. 2017 01 17; 18(3):762-776. PMID: 28099853; PMCID: PMC5419050.
    Citations: 247     Fields:    Translation:AnimalsCells
  22. Gunbin K, Peshkin L, Popadin K, Annis S, Ackermann RR, Khrapko K. Integration of mtDNA pseudogenes into the nuclear genome coincides with speciation of the human genus. A hypothesis. Mitochondrion. 2017 05; 34:20-23. PMID: 27979772.
    Citations: 3     Fields:    Translation:Humans
  23. Wlizla M, Falco R, Peshkin L, Parlow AF, Horb ME. Luteinizing Hormone is an effective replacement for hCG to induce ovulation in Xenopus. Dev Biol. 2017 06 15; 426(2):442-448. PMID: 27263125; PMCID: PMC5135639.
    Citations: 7     Fields:    Translation:HumansAnimals
  24. Gladilin E, Eils R, Peshkin L. On the embryonic cell division beyond the contractile ring mechanism: experimental and computational investigation of effects of vitelline confinement, temperature and egg size. PeerJ. 2015; 3:e1490. PMID: 26713241; PMCID: PMC4690382.
    Citations: 3     
  25. Simakov O, Kawashima T, Marlétaz F, Jenkins J, Koyanagi R, Mitros T, Hisata K, Bredeson J, Shoguchi E, Gyoja F, Yue JX, Chen YC, Freeman RM, Sasaki A, Hikosaka-Katayama T, Sato A, Fujie M, Baughman KW, Levine J, Gonzalez P, Cameron C, Fritzenwanker JH, Pani AM, Goto H, Kanda M, Arakaki N, Yamasaki S, Qu J, Cree A, Ding Y, Dinh HH, Dugan S, Holder M, Jhangiani SN, Kovar CL, Lee SL, Lewis LR, Morton D, Nazareth LV, Okwuonu G, Santibanez J, Chen R, Richards S, Muzny DM, Gillis A, Peshkin L, Wu M, Humphreys T, Su YH, Putnam NH, Schmutz J, Fujiyama A, Yu JK, Tagawa K, Worley KC, Gibbs RA, Kirschner MW, Lowe CJ, Satoh N, Rokhsar DS, Gerhart J. Hemichordate genomes and deuterostome origins. Nature. 2015 Nov 26; 527(7579):459-65. PMID: 26580012.
    Citations: 76     Fields:    Translation:AnimalsCells
  26. Peshkin L, Wühr M, Pearl E, Haas W, Freeman RM, Gerhart JC, Klein AM, Horb M, Gygi SP, Kirschner MW. On the Relationship of Protein and mRNA Dynamics in Vertebrate Embryonic Development. Dev Cell. 2015 Nov 09; 35(3):383-94. PMID: 26555057; PMCID: PMC4776761.
    Citations: 91     Fields:    Translation:AnimalsCells
  27. Wühr M, Güttler T, Peshkin L, McAlister GC, Sonnett M, Ishihara K, Groen AC, Presler M, Erickson BK, Mitchison TJ, Kirschner MW, Gygi SP. The Nuclear Proteome of a Vertebrate. Curr Biol. 2015 Oct 19; 25(20):2663-71. PMID: 26441354; PMCID: PMC4618192.
    Citations: 63     Fields:    Translation:AnimalsCells
  28. Klein AM, Mazutis L, Akartuna I, Tallapragada N, Veres A, Li V, Peshkin L, Weitz DA, Kirschner MW. Droplet barcoding for single-cell transcriptomics applied to embryonic stem cells. Cell. 2015 May 21; 161(5):1187-1201. PMID: 26000487; PMCID: PMC4441768.
    Citations: 1083     Fields:    Translation:AnimalsCells
  29. Gujral TS, Chan M, Peshkin L, Sorger PK, Kirschner MW, MacBeath G. A noncanonical Frizzled2 pathway regulates epithelial-mesenchymal transition and metastasis. Cell. 2014 Nov 06; 159(4):844-56. PMID: 25417160.
    Citations: 163     Fields:    Translation:HumansAnimalsCells
  30. Wühr M, Freeman RM, Presler M, Horb ME, Peshkin L, Gygi S, Kirschner MW. Deep proteomics of the Xenopus laevis egg using an mRNA-derived reference database. Curr Biol. 2014 Jul 07; 24(13):1467-1475. PMID: 24954049.
    Citations: 117     Fields:    Translation:AnimalsCells
  31. Mattison JA, Wang M, Bernier M, Zhang J, Park SS, Maudsley S, An SS, Santhanam L, Martin B, Faulkner S, Morrell C, Baur JA, Peshkin L, Sosnowska D, Csiszar A, Herbert RL, Tilmont EM, Ungvari Z, Pearson KJ, Lakatta EG, de Cabo R. Resveratrol prevents high fat/sucrose diet-induced central arterial wall inflammation and stiffening in nonhuman primates. Cell Metab. 2014 Jul 01; 20(1):183-90. PMID: 24882067.
    Citations: 97     Fields:    Translation:HumansAnimalsCells
  32. Gujral TS, Peshkin L, Kirschner MW. Exploiting polypharmacology for drug target deconvolution. Proc Natl Acad Sci U S A. 2014 Apr 01; 111(13):5048-53. PMID: 24707051.
    Citations: 35     Fields:    Translation:HumansCells
  33. Wühr M, Haas W, McAlister GC, Peshkin L, Rad R, Kirschner MW, Gygi SP. Accurate multiplexed proteomics at the MS2 level using the complement reporter ion cluster. Anal Chem. 2012 Nov 06; 84(21):9214-21. PMID: 23098179.
    Citations: 50     Fields:    Translation:Humans
  34. Kim S, Peshkin L, Mitchison TJ. Vascular disrupting agent drug classes differ in effects on the cytoskeleton. PLoS One. 2012; 7(7):e40177. PMID: 22848372.
    Citations: 8     Fields:    Translation:HumansAnimalsCells
  35. Ball MP, Thakuria JV, Zaranek AW, Clegg T, Rosenbaum AM, Wu X, Angrist M, Bhak J, Bobe J, Callow MJ, Cano C, Chou MF, Chung WK, Douglas SM, Estep PW, Gore A, Hulick P, Labarga A, Lee JH, Lunshof JE, Kim BC, Kim JI, Li Z, Murray MF, Nilsen GB, Peters BA, Raman AM, Rienhoff HY, Robasky K, Wheeler MT, Vandewege W, Vorhaus DB, Yang JL, Yang L, Aach J, Ashley EA, Drmanac R, Kim SJ, Li JB, Peshkin L, Seidman CE, Seo JS, Zhang K, Rehm HL, Church GM. A public resource facilitating clinical use of genomes. Proc Natl Acad Sci U S A. 2012 Jul 24; 109(30):11920-7. PMID: 22797899.
    Citations: 95     Fields:    Translation:HumansCells
  36. Beer R, Wagner F, Grishkevich V, Peshkin L, Yanai I. Toward an unbiased evolutionary platform for unraveling Xenopus developmental gene networks. Genesis. 2012 Mar; 50(3):186-91. PMID: 21956895.
    Citations: 1     Fields:    Translation:Animals
  37. Kim EB, Fang X, Fushan AA, Huang Z, Lobanov AV, Han L, Marino SM, Sun X, Turanov AA, Yang P, Yim SH, Zhao X, Kasaikina MV, Stoletzki N, Peng C, Polak P, Xiong Z, Kiezun A, Zhu Y, Chen Y, Kryukov GV, Zhang Q, Peshkin L, Yang L, Bronson RT, Buffenstein R, Wang B, Han C, Li Q, Chen L, Zhao W, Sunyaev SR, Park TJ, Zhang G, Wang J, Gladyshev VN. Genome sequencing reveals insights into physiology and longevity of the naked mole rat. Nature. 2011 Oct 12; 479(7372):223-7. PMID: 21993625.
    Citations: 247     Fields:    Translation:HumansAnimalsCells
  38. Yanai I, Peshkin L, Jorgensen P, Kirschner MW. Mapping gene expression in two Xenopus species: evolutionary constraints and developmental flexibility. Dev Cell. 2011 Apr 19; 20(4):483-96. PMID: 21497761.
    Citations: 97     Fields:    Translation:Animals
  39. Vastag L, Jorgensen P, Peshkin L, Wei R, Rabinowitz JD, Kirschner MW. Remodeling of the metabolome during early frog development. PLoS One. 2011 Feb 04; 6(2):e16881. PMID: 21347444.
    Citations: 37     Fields:    Translation:Animals
  40. Adzhubei IA, Schmidt S, Peshkin L, Ramensky VE, Gerasimova A, Bork P, Kondrashov AS, Sunyaev SR. A method and server for predicting damaging missense mutations. Nat Methods. 2010 Apr; 7(4):248-9. PMID: 20354512; PMCID: PMC2855889.
    Citations: 5944     Fields:    Translation:Humans
  41. Voolstra CR, Schnetzer J, Peshkin L, Randall CJ, Szmant AM, Medina M. Effects of temperature on gene expression in embryos of the coral Montastraea faveolata. BMC Genomics. 2009 Dec 23; 10:627. PMID: 20030803.
    Citations: 47     Fields:    Translation:Animals
  42. Cano C, Blanco A, Peshkin L. Automated identification of diagnosis and co-morbidity in clinical records. Methods Inf Med. 2009; 48(6):546-51. PMID: 19696949.
    Citations: 2     Fields:    Translation:Humans
  43. Cano C, Monaghan T, Blanco A, Wall DP, Peshkin L. Collaborative text-annotation resource for disease-centered relation extraction from biomedical text. J Biomed Inform. 2009 Oct; 42(5):967-77. PMID: 19232400.
    Citations: 8     Fields:    Translation:Humans
  44. Pearson KJ, Baur JA, Lewis KN, Peshkin L, Price NL, Labinskyy N, Swindell WR, Kamara D, Minor RK, Perez E, Jamieson HA, Zhang Y, Dunn SR, Sharma K, Pleshko N, Woollett LA, Csiszar A, Ikeno Y, Le Couteur D, Elliott PJ, Becker KG, Navas P, Ingram DK, Wolf NS, Ungvari Z, Sinclair DA, de Cabo R. Resveratrol delays age-related deterioration and mimics transcriptional aspects of dietary restriction without extending life span. Cell Metab. 2008 Aug; 8(2):157-68. PMID: 18599363.
    Citations: 494     Fields:    Translation:AnimalsCells
  45. Wellner B, Huyck M, Mardis S, Aberdeen J, Morgan A, Peshkin L, Yeh A, Hitzeman J, Hirschman L. Rapidly retargetable approaches to de-identification in medical records. J Am Med Inform Assoc. 2007 Sep-Oct; 14(5):564-73. PMID: 17600096.
    Citations: 49     Fields:    Translation:Humans
  46. Deluca TF, Wu IH, Pu J, Monaghan T, Peshkin L, Singh S, Wall DP. Roundup: a multi-genome repository of orthologs and evolutionary distances. Bioinformatics. 2006 Aug 15; 22(16):2044-6. PMID: 16777906.
    Citations: 60     Fields:    
  47. Peshkin L, Gelfand MS. Segmentation of yeast DNA using hidden Markov models. Bioinformatics. 1999 Dec; 15(12):980-6. PMID: 10745987.
    Citations: 7     Fields:    Translation:Animals
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.