Contact, publication, and social network information about Harvard faculty and fellows. Harvard Catalyst Profiles
Keywords
Last Name
Institution

profileLeonid Peshkin, Ph.D.

TitleLecturer on Systems Biology
InstitutionHarvard Medical School
DepartmentSystems Biology
AddressHarvard Medical School
Alpert 536, Systems Biology
200 Longwood Ave
Boston MA 02115
Phone617/432-5483
vCardDownload vCard (login for email)
Profile Picture

Collapse Bibliographic 
Collapse selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
List All   |   Timeline
  1. Gunbin K, Peshkin L, Popadin K, Annis S, Ackermann RR, Khrapko K. Data on the time of integration of the human mitochondrial pseudogenes (NUMTs) into the nuclear genome. Data Brief. 2017 Aug; 13:536-544. PMID: 28702491.
    View in: PubMed
  2. Savova V, Pearl EJ, Boke E, Nag A, Adzhubei I, Horb ME, Peshkin L. Transcriptomic insights into genetic diversity of protein-coding genes in X. laevis. Dev Biol. 2017 Apr 15; 424(2):181-188. PMID: 28283406.
    View in: PubMed
  3. Bryant DM, Johnson K, DiTommaso T, Tickle T, Couger MB, Payzin-Dogru D, Lee TJ, Leigh ND, Kuo TH, Davis FG, Bateman J, Bryant S, Guzikowski AR, Tsai SL, Coyne S, Ye WW, Freeman RM, Peshkin L, Tabin CJ, Regev A, Haas BJ, Whited JL. A Tissue-Mapped Axolotl De Novo Transcriptome Enables Identification of Limb Regeneration Factors. Cell Rep. 2017 Jan 17; 18(3):762-776. PMID: 28099853.
    View in: PubMed
  4. Gunbin K, Peshkin L, Popadin K, Annis S, Ackermann RR, Khrapko K. Integration of mtDNA pseudogenes into the nuclear genome coincides with speciation of the human genus. A hypothesis. Mitochondrion. 2017 May; 34:20-23. PMID: 27979772.
    View in: PubMed
  5. Wlizla M, Falco R, Peshkin L, Parlow AF, Horb ME. Luteinizing Hormone is an effective replacement for hCG to induce ovulation in Xenopus. Dev Biol. 2017 Jun 15; 426(2):442-448. PMID: 27263125.
    View in: PubMed
  6. Gladilin E, Eils R, Peshkin L. On the embryonic cell division beyond the contractile ring mechanism: experimental and computational investigation of effects of vitelline confinement, temperature and egg size. PeerJ. 2015; 3:e1490. PMID: 26713241; PMCID: PMC4690382.
  7. Simakov O, Kawashima T, Marlétaz F, Jenkins J, Koyanagi R, Mitros T, Hisata K, Bredeson J, Shoguchi E, Gyoja F, Yue JX, Chen YC, Freeman RM, Sasaki A, Hikosaka-Katayama T, Sato A, Fujie M, Baughman KW, Levine J, Gonzalez P, Cameron C, Fritzenwanker JH, Pani AM, Goto H, Kanda M, Arakaki N, Yamasaki S, Qu J, Cree A, Ding Y, Dinh HH, Dugan S, Holder M, Jhangiani SN, Kovar CL, Lee SL, Lewis LR, Morton D, Nazareth LV, Okwuonu G, Santibanez J, Chen R, Richards S, Muzny DM, Gillis A, Peshkin L, Wu M, Humphreys T, Su YH, Putnam NH, Schmutz J, Fujiyama A, Yu JK, Tagawa K, Worley KC, Gibbs RA, Kirschner MW, Lowe CJ, Satoh N, Rokhsar DS, Gerhart J. Hemichordate genomes and deuterostome origins. Nature. 2015 Nov 26; 527(7579):459-65. PMID: 26580012; PMCID: PMC4729200.
  8. Peshkin L, Wühr M, Pearl E, Haas W, Freeman RM, Gerhart JC, Klein AM, Horb M, Gygi SP, Kirschner MW. On the Relationship of Protein and mRNA Dynamics in Vertebrate Embryonic Development. Dev Cell. 2015 Nov 09; 35(3):383-94. PMID: 26555057; PMCID: PMC4776761 [Available on 11/09/16].
  9. Wühr M, Güttler T, Peshkin L, McAlister GC, Sonnett M, Ishihara K, Groen AC, Presler M, Erickson BK, Mitchison TJ, Kirschner MW, Gygi SP. The Nuclear Proteome of a Vertebrate. Curr Biol. 2015 Oct 19; 25(20):2663-71. PMID: 26441354; PMCID: PMC4618192 [Available on 10/19/16].
  10. Klein AM, Mazutis L, Akartuna I, Tallapragada N, Veres A, Li V, Peshkin L, Weitz DA, Kirschner MW. Droplet barcoding for single-cell transcriptomics applied to embryonic stem cells. Cell. 2015 May 21; 161(5):1187-201. PMID: 26000487; PMCID: PMC4441768.
  11. Gujral TS, Chan M, Peshkin L, Sorger PK, Kirschner MW, MacBeath G. A noncanonical Frizzled2 pathway regulates epithelial-mesenchymal transition and metastasis. Cell. 2014 Nov 06; 159(4):844-56. PMID: 25417160; PMCID: PMC4243058.
  12. Wühr M, Freeman RM, Presler M, Horb ME, Peshkin L, Gygi S, Kirschner MW. Deep proteomics of the Xenopus laevis egg using an mRNA-derived reference database. Curr Biol. 2014 Jul 07; 24(13):1467-1475. PMID: 24954049; PMCID: PMC4090281.
  13. Mattison JA, Wang M, Bernier M, Zhang J, Park SS, Maudsley S, An SS, Santhanam L, Martin B, Faulkner S, Morrell C, Baur JA, Peshkin L, Sosnowska D, Csiszar A, Herbert RL, Tilmont EM, Ungvari Z, Pearson KJ, Lakatta EG, de Cabo R. Resveratrol prevents high fat/sucrose diet-induced central arterial wall inflammation and stiffening in nonhuman primates. Cell Metab. 2014 Jul 01; 20(1):183-90. PMID: 24882067; PMCID: PMC4254394.
  14. Gujral TS, Peshkin L, Kirschner MW. Exploiting polypharmacology for drug target deconvolution. Proc Natl Acad Sci U S A. 2014 Apr 01; 111(13):5048-53. PMID: 24707051; PMCID: PMC3977247.
  15. Wühr M, Haas W, McAlister GC, Peshkin L, Rad R, Kirschner MW, Gygi SP. Accurate multiplexed proteomics at the MS2 level using the complement reporter ion cluster. Anal Chem. 2012 Nov 06; 84(21):9214-21. PMID: 23098179; PMCID: PMC3771681.
  16. Kim S, Peshkin L, Mitchison TJ. Vascular disrupting agent drug classes differ in effects on the cytoskeleton. PLoS One. 2012; 7(7):e40177. PMID: 22848372; PMCID: PMC3404093.
  17. Ball MP, Thakuria JV, Zaranek AW, Clegg T, Rosenbaum AM, Wu X, Angrist M, Bhak J, Bobe J, Callow MJ, Cano C, Chou MF, Chung WK, Douglas SM, Estep PW, Gore A, Hulick P, Labarga A, Lee JH, Lunshof JE, Kim BC, Kim JI, Li Z, Murray MF, Nilsen GB, Peters BA, Raman AM, Rienhoff HY, Robasky K, Wheeler MT, Vandewege W, Vorhaus DB, Yang JL, Yang L, Aach J, Ashley EA, Drmanac R, Kim SJ, Li JB, Peshkin L, Seidman CE, Seo JS, Zhang K, Rehm HL, Church GM. A public resource facilitating clinical use of genomes. Proc Natl Acad Sci U S A. 2012 Jul 24; 109(30):11920-7. PMID: 22797899; PMCID: PMC3409785.
  18. Beer R, Wagner F, Grishkevich V, Peshkin L, Yanai I. Toward an unbiased evolutionary platform for unraveling Xenopus developmental gene networks. Genesis. 2012 Mar; 50(3):186-91. PMID: 21956895.
    View in: PubMed
  19. Kim EB, Fang X, Fushan AA, Huang Z, Lobanov AV, Han L, Marino SM, Sun X, Turanov AA, Yang P, Yim SH, Zhao X, Kasaikina MV, Stoletzki N, Peng C, Polak P, Xiong Z, Kiezun A, Zhu Y, Chen Y, Kryukov GV, Zhang Q, Peshkin L, Yang L, Bronson RT, Buffenstein R, Wang B, Han C, Li Q, Chen L, Zhao W, Sunyaev SR, Park TJ, Zhang G, Wang J, Gladyshev VN. Genome sequencing reveals insights into physiology and longevity of the naked mole rat. Nature. 2011 Oct 12; 479(7372):223-7. PMID: 21993625; PMCID: PMC3319411.
  20. Yanai I, Peshkin L, Jorgensen P, Kirschner MW. Mapping gene expression in two Xenopus species: evolutionary constraints and developmental flexibility. Dev Cell. 2011 Apr 19; 20(4):483-96. PMID: 21497761; PMCID: PMC3118554.
  21. Vastag L, Jorgensen P, Peshkin L, Wei R, Rabinowitz JD, Kirschner MW. Remodeling of the metabolome during early frog development. PLoS One. 2011 Feb 04; 6(2):e16881. PMID: 21347444; PMCID: PMC3035664.
  22. Adzhubei IA, Schmidt S, Peshkin L, Ramensky VE, Gerasimova A, Bork P, Kondrashov AS, Sunyaev SR. A method and server for predicting damaging missense mutations. Nat Methods. 2010 Apr; 7(4):248-9. PMID: 20354512; PMCID: PMC2855889.
  23. Voolstra CR, Schnetzer J, Peshkin L, Randall CJ, Szmant AM, Medina M. Effects of temperature on gene expression in embryos of the coral Montastraea faveolata. BMC Genomics. 2009 Dec 23; 10:627. PMID: 20030803; PMCID: PMC2807443.
  24. Cano C, Blanco A, Peshkin L. Automated identification of diagnosis and co-morbidity in clinical records. Methods Inf Med. 2009; 48(6):546-51. PMID: 19696949.
    View in: PubMed
  25. Cano C, Monaghan T, Blanco A, Wall DP, Peshkin L. Collaborative text-annotation resource for disease-centered relation extraction from biomedical text. J Biomed Inform. 2009 Oct; 42(5):967-77. PMID: 19232400; PMCID: PMC2757509.
  26. Pearson KJ, Baur JA, Lewis KN, Peshkin L, Price NL, Labinskyy N, Swindell WR, Kamara D, Minor RK, Perez E, Jamieson HA, Zhang Y, Dunn SR, Sharma K, Pleshko N, Woollett LA, Csiszar A, Ikeno Y, Le Couteur D, Elliott PJ, Becker KG, Navas P, Ingram DK, Wolf NS, Ungvari Z, Sinclair DA, de Cabo R. Resveratrol delays age-related deterioration and mimics transcriptional aspects of dietary restriction without extending life span. Cell Metab. 2008 Aug; 8(2):157-68. PMID: 18599363; PMCID: PMC2538685.
  27. Wellner B, Huyck M, Mardis S, Aberdeen J, Morgan A, Peshkin L, Yeh A, Hitzeman J, Hirschman L. Rapidly retargetable approaches to de-identification in medical records. J Am Med Inform Assoc. 2007 Sep-Oct; 14(5):564-73. PMID: 17600096; PMCID: PMC1975794.
  28. Deluca TF, Wu IH, Pu J, Monaghan T, Peshkin L, Singh S, Wall DP. Roundup: a multi-genome repository of orthologs and evolutionary distances. Bioinformatics. 2006 Aug 15; 22(16):2044-6. PMID: 16777906.
    View in: PubMed
  29. Peshkin L, Gelfand MS. Segmentation of yeast DNA using hidden Markov models. Bioinformatics. 1999 Dec; 15(12):980-6. PMID: 10745987.
    View in: PubMed
Local representatives can answer questions about the Profiles website or help with editing a profile or issues with profile data. For assistance with this profile: HMS/HSDM faculty should contact feedbackcatalyst.harvard.edu. For faculty or fellow appointment updates and changes, please ask your appointing department to contact HMS. For fellow personal and demographic information, contact HMS Human Resources at human_resourceshms.harvard.edu. For faculty personal and demographic information, contact HMS Office for Faculty Affairs at facappthms.harvard.edu.
Peshkin's Networks
Click the "See All" links for more information and interactive visualizations!
Concepts Expand Description
_
Co-Authors Expand Description
_
Similar People Expand Description
_
Same Department Expand Description
Physical Neighbors Expand Description
_