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Maurizio Fava, M.D.

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Institution
Department

Biography
1997
Hugo DeCuyper Lecture
1998
Robert Kellner Lecture/Robert Kellner Research Symposium
2005
Outstanding Psychiatrist Award
2005
Psychopharmacology Supervision Award
2006
Distinguished Fellow Award
2009
A. Clifford Barger Excellence in Mentoring Award
2013 - 2015
President
2012
John T. Potts, Jr., MD Faculty Mentoring Award
2016
Gerald L. Klerman Senior Investigator Award

Overview
Narrative Report of Research, Teaching, and Clinical Contributions:
Dr. Fava is currently Director, Division of Clinical Research of the Massachusetts General Hospital (MGH) Research Institute, Executive Vice Chair, Department of Psychiatry at MGH, and Executive Director of the MGH Clinical Trials Network and Institute (CTNI), as well as Slater Family Professor of Psychiatry at Harvard Medical School. Dr. Fava founded the Depression Clinical and Research Program (DCRP) at MGH in 1990 and was Director of the DCRP from 1990 to 2014, when he became Director of Clinical Research at MGH. Under Dr. Fava’s direction, the DCRP became one of the leading centers for the study of Unipolar Depressive Disorders in the world. Dr. Fava was the co-Principal Investigator with Dr. A.John Rush of the largest clinical trial ever conducted in depression, STAR*D, whose findings were published in journals such NEJM and JAMA. In addition to his numerous clinical trials and studies in treatment resistant depression, Dr. Fava has contributed significantly to the field of psychiatric research in a number of other areas. He has identified a subtype of depressive disorder characterized by marked irritability and “anger attacks.” His innovative work has led to the discovery that these individuals present a blunted prolactin response to fenfluramine challenge, are more likely to have brain white matter hyperintensities, and may selectively respond to serotonergic compounds. In addition, Dr. Fava has conducted important investigations on the role of folate deficiency in depression and on the efficacy in depression of one carbon cycle elements with putative antidepressant effects such as s-adenosyl-methionine (SAMe) and methylfolate. His pioneering work in this area led to his R-01 grant on the efficacy of SAMe in major depressive disorder (MDD) and to the successful trial of SAMe augmentation in resistant depression, published in the Am J Psychiatry. He has conducted and published the first prospective, placebo-controlled study of discontinuation-emergent adverse events of the newer antidepressants and he has designed and developed a protocol for the first, large multicenter study on the effects of abrupt interruption of SSRI treatment. He has completed a large single-site study of bupropion augmentation of the nicotine patch in depressed smokers (as part of one of his previous R01s) and he was the PI of a large, 9-year U-01 aimed at developing new treatments for nicotine dependence. He has developed with Dr. David Schoenfeld a novel design (with over five patents) to address the problem of excessive placebo response in drug trials and to markedly reduce sample size requirements for these trials. He has also been very active in developing new instruments to measure the effects of antidepressants treatments, and several of his validated instruments (such as the DESS scale, SFQ scale, the CPFQ scale, and the SDQ scale) are being used by clinical investigators all over the world. With respect to his publications, Dr. Fava has authored or co-authored over 700 original articles published in refereed medical journals with international circulation, cited over 55,000 times in the literature, with an h index greater than 115. He has also edited eight books, and he has published more than 80 chapters/reviews and over 600 abstracts. In 2007, he founded and is now the Executive Director of the MGH Psychiatry Clinical Trials Network and Institute (CTNI), the first academic CRO specialized in the coordination of multi-center clinical trials in psychiatry. The MGH CTNI is currently conducting numerous large multi-center clinical trials and helping develop new treatments for psychiatric disorders. Dr. Fava has been the PI of the large NIMH-sponsored RAPID contract, aimed at studying novel treatments for depression with rapid antidepressant effects through a network of academic sites coordinated by the MGH CTNI. Over the past 30 years, Dr. Fava has also been successful in obtaining over $95,000,000 in funding for his program, as principal or co-principal investigator, from the National Institute of Health, other federal agencies, foundations, and pharmaceutical industries. In April 2014, Dr. Fava was named Director of the Clinical Research Program (CRP) at Massachusetts General Hospital (MGH) and is now the Director, Division of Clinical Research of the MGH Research Institute at the Massachusetts General Hospital (MGH).

Dr. Fava has an excellent track record as a teacher and has been very active in instructing and supervising psychiatric residents and fellows. Over the past 25 years, Dr. Fava has also trained and mentored over 50 research fellows/junior faculty in his program, many of whom have continued to work in the area of psychiatric research following completion of their fellowship. Dr. Fava has also been the mentor/sponsor for over 30 successful NARSAD, APA, and K Award fellowship applications (he is currently mentoring three K-23 Award recipients), and he has received the A. Clifford Barger Excellence in Mentoring Award, Harvard Medical School and the John T. Potts, Jr., MD Faculty Mentoring Award/2012. Over the past several years, he has organized and chaired numerous national and international symposia and has served on many advisory panels for pharmaceutical companies. In addition, he has reviewed grant proposals and specific RFP concepts/contracts for the National Institute of Mental Health, the National Institute of Drug Abuse, and the NCCAM. Dr. Fava is currently the co-director of the Psychopharmacology Course of the MGH Psychiatry Academy, one of the most highly attended courses in the country, with approximately 600 participants each year. Dr. Fava has also lectured extensively, with over 350 presentations at national and international meetings and conferences. Dr. Fava was elected President of the American Society of Clinical Psychopharmacology (ASCP) from 2013 until 2015.

Dr. Fava is considered an expert psychopharmacologist in the area of depression and frequently provides consultations to difficult cases referred to him from all over the world. He has been for the past 20 years in charge of a large PO group practice of clinicians specialized in the treatment of patients with mood disorders, and his leadership skills have been critical to the financial success of this group.

Research
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. R01MH102279 (FAVA, MAURIZIO) Sep 18, 2015 - Jun 30, 2020
    NIH/NIMH
    Neurobiological Underpinnings of Placebo Response in Depression
    Role: Co-Principal Investigator
  2. R34MH099315 (MILLER, KAREN K) Jul 15, 2013 - Jun 30, 2016
    NIH/NIMH
    1/2-Collaborative Study: Testosterone Antidepressant Augmentation in Women
    Role: Principal Investigator
  3. R25MH094612 (FAVA, MAURIZIO) Jun 1, 2011 - Mar 31, 2022
    NIH/NIMH
    Fostering Research Mentorship and Training During Psychiatry Residency
    Role: Principal Investigator
  4. R01DA030992 (EVINS, A EDEN) Apr 1, 2011 - Jul 31, 2016
    NIH/NIDA
    Proof-of-Concept Trial of an Alpha-7 Nicotinic Agonist for Nicotine Dependence
    Role: Co-Principal Investigator
  5. R01MH085050 (FAVA, MAURIZIO) Aug 1, 2010 - Apr 30, 2014
    NIH/NIMH
    3/3-Efficacy and Tolerability of Riluzole in Treatment-Resistant Depression
    Role: Principal Investigator

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Fava M, Durgam S, Earley W, Lu K, Hayes R, Laszlovszky I, Németh G. Efficacy of adjunctive low-dose cariprazine in major depressive disorder: a randomized, double-blind, placebo-controlled trial. Int Clin Psychopharmacol. 2018 Nov; 33(6):312-321. PMID: 30045066.
    View in: PubMed
  2. Fava M, Freeman MP, Flynn M, Judge H, Hoeppner BB, Cusin C, Ionescu DF, Mathew SJ, Chang LC, Iosifescu DV, Murrough J, Debattista C, Schatzberg AF, Trivedi MH, Jha MK, Sanacora G, Wilkinson ST, Papakostas GI. Double-blind, placebo-controlled, dose-ranging trial of intravenous ketamine as adjunctive therapy in treatment-resistant depression (TRD). Mol Psychiatry. 2018 Oct 03. PMID: 30283029.
    View in: PubMed
  3. Choi KW, Na EJ, Fava M, Mischoulon D, Cho H, Jeon HJ. Increased adrenocorticotropic hormone (ACTH) levels predict severity of depression after six months of follow-up in outpatients with major depressive disorder. Psychiatry Res. 2018 Sep 21; 270:246-252. PMID: 30269042.
    View in: PubMed
  4. Kim H, Choi KW, Na EJ, Hong JP, Fava M, Mischoulon D, Cho H, Jeon HJ. Anxiety attacks with or without life-threatening situations, major depressive disorder, and suicide attempt: a nationwide community sample of Korean adults. Psychiatry Res. 2018 Sep 21; 270:257-263. PMID: 30273856.
    View in: PubMed
  5. Ionescu DF, Bentley KH, Eikermann M, Taylor N, Johnson-Akeju O, Swee MB, Pavone KJ, Petrie SR, Dording C, Mischoulon D, Alpert JE, Brown EN, Baer L, Nock MK, Fava M, Cusin C. Repeat-dose ketamine augmentation for treatment-resistant depression with chronic suicidal ideation: A randomized, double blind, placebo controlled trial. J Affect Disord. 2018 Sep 17; 243:516-524. PMID: 30286416.
    View in: PubMed
  6. Cassano P, Dording C, Thomas G, Foster S, Yeung A, Uchida M, Hamblin MR, Bui E, Fava M, Mischoulon D, Iosifescu DV. Effects of transcranial photobiomodulation with near-infrared light on sexual dysfunction. Lasers Surg Med. 2018 Sep 17. PMID: 30221776.
    View in: PubMed
  7. Shapero BG, Gibb BE, Archibald A, Wilens TE, Fava M, Hirshfeld-Becker DR. Risk Factors for Depression in Adolescents With ADHD: The Impact of Cognitive Biases and Stress. J Atten Disord. 2018 Sep 10; 1087054718797447. PMID: 30198368.
    View in: PubMed
  8. Laferton JAC, Vijapura S, Baer L, Clain AJ, Cooper A, Papakostas G, Price LH, Carpenter LL, Tyrka AR, Fava M, Mischoulon D. Mechanisms of Perceived Treatment Assignment and Subsequent Expectancy Effects in a Double Blind Placebo Controlled RCT of Major Depression. Front Psychiatry. 2018; 9:424. PMID: 30245644.
    View in: PubMed
  9. Yang J, Zhang M, Ahn H, Zhang Q, Jin TB, Li IA, Nemesure M, Joshi N, Jiang H, Miller JM, Ogden RT, Petkova E, Milak MS, Sublette ME, Sullivan GM, Trivedi MH, Weissman M, McGrath PJ, Fava M, Kurian BT, Pizzagalli DA, Cooper CM, McInnis M, Oquendo MA, Mann JJ, Parsey RV, DeLorenzo C. Development and evaluation of a multimodal marker of major depressive disorder. Hum Brain Mapp. 2018 Aug 16. PMID: 30113112.
    View in: PubMed
  10. Trivedi MH, South C, Jha MK, Rush AJ, Cao J, Kurian B, Phillips M, Pizzagalli DA, Trombello JM, Oquendo MA, Cooper C, Dillon DG, Webb C, Grannemann BD, Bruder G, McGrath PJ, Parsey R, Weissman M, Fava M. A Novel Strategy to Identify Placebo Responders: Prediction Index of Clinical and Biological Markers in the EMBARC Trial. Psychother Psychosom. 2018; 87(5):285-295. PMID: 30110685.
    View in: PubMed
  11. Fava M, Mahableshwarkar AR, Jacobson W, Zhong W, Keefe RS, Olsen CK, Jaeger J. What is the overlap between subjective and objective cognitive impairments in MDD? Ann Clin Psychiatry. 2018 Aug; 30(3):176-184. PMID: 30028891.
    View in: PubMed
  12. Schuster RM, Pachas GN, Stoeckel L, Cather C, Nadal M, Mischoulon D, Schoenfeld DA, Zhang H, Ulysse C, Dodds EB, Sobolewski S, Hudziak V, Hanly A, Fava M, Evins AE. Phase IIb Trial of an a7 Nicotinic Receptor Partial Agonist With and Without Nicotine Patch for Withdrawal-Associated Cognitive Deficits and Tobacco Abstinence. J Clin Psychopharmacol. 2018 Aug; 38(4):307-316. PMID: 29912798.
    View in: PubMed
  13. Webb CA, Trivedi MH, Cohen ZD, Dillon DG, Fournier JC, Goer F, Fava M, McGrath PJ, Weissman M, Parsey R, Adams P, Trombello JM, Cooper C, Deldin P, Oquendo MA, McInnis MG, Huys Q, Bruder G, Kurian BT, Jha M, DeRubeis RJ, Pizzagalli DA. Personalized prediction of antidepressant v. placebo response: evidence from the EMBARC study. Psychol Med. 2018 Jul 02; 1-10. PMID: 29962359.
    View in: PubMed
  14. Yu M, Linn KA, Cook PA, Phillips ML, McInnis M, Fava M, Trivedi MH, Weissman MM, Shinohara RT, Sheline YI. Statistical harmonization corrects site effects in functional connectivity measurements from multi-site fMRI data. Hum Brain Mapp. 2018 Jul 01. PMID: 29962049.
    View in: PubMed
  15. Pedrelli P, MacPherson L, Khan AJ, Shapero BG, Fisher LB, Nyer M, Cassano P, Parnarouskis L, Farabaugh A, Fava M, Silveri MM. Sex Differences in the Association between Heavy Drinking and Behavioral Distress Tolerance and Emotional Reactivity Among Non-Depressed College Students. Alcohol Alcohol. 2018 Jun 27. PMID: 29947730.
    View in: PubMed
  16. Baek JH, Kim K, Hong JP, Cho MJ, Fava M, Mischoulon D, Chang SM, Kim JY, Cho H, Jeon HJ. Binge eating, trauma, and suicide attempt in community adults with major depressive disorder. PLoS One. 2018; 13(6):e0198192. PMID: 29927937.
    View in: PubMed
  17. Bartlett EA, DeLorenzo C, Sharma P, Yang J, Zhang M, Petkova E, Weissman M, McGrath PJ, Fava M, Ogden RT, Kurian BT, Malchow A, Cooper CM, Trombello JM, McInnis M, Adams P, Oquendo MA, Pizzagalli DA, Trivedi M, Parsey RV. Pretreatment and early-treatment cortical thickness is associated with SSRI treatment response in major depressive disorder. Neuropsychopharmacology. 2018 Oct; 43(11):2221-2230. PMID: 29955151.
    View in: PubMed
  18. Pizzagalli DA, Webb CA, Dillon DG, Tenke CE, Kayser J, Goer F, Fava M, McGrath P, Weissman M, Parsey R, Adams P, Trombello J, Cooper C, Deldin P, Oquendo MA, McInnis MG, Carmody T, Bruder G, Trivedi MH. Pretreatment Rostral Anterior Cingulate Cortex Theta Activity in Relation to Symptom Improvement in Depression: A Randomized Clinical Trial. JAMA Psychiatry. 2018 Jun 01; 75(6):547-554. PMID: 29641834.
    View in: PubMed
  19. Curren L, Huz I, McKee M, Traeger L, Bedoya CA, Chang TE, Cassano P, Fava M, Alpert J, Yeung A, Gilman SE, Trinh NH. Patient primary language in a culturally focused intervention for Latino Americans with depression. Ann Clin Psychiatry. 2018 May; 30(2):84-90. PMID: 29697708.
    View in: PubMed
  20. Trombello JM, Pizzagalli DA, Weissman MM, Grannemann BD, Cooper CM, Greer TL, Malchow AL, Jha MK, Carmody TJ, Kurian BT, Webb CA, Dillon DG, McGrath PJ, Bruder G, Fava M, Parsey RV, McInnis MG, Adams P, Trivedi MH. Characterizing anxiety subtypes and the relationship to behavioral phenotyping in major depression: Results from the EMBARC study. J Psychiatr Res. 2018 Jul; 102:207-215. PMID: 29689518.
    View in: PubMed
  21. Nyer M, Gerbarg PL, Silveri MM, Johnston J, Scott TM, Nauphal M, Owen L, Nielsen GH, Mischoulon D, Brown RP, Fava M, Streeter CC. A randomized controlled dosing study of Iyengar yoga and coherent breathing for the treatment of major depressive disorder: Impact on suicidal ideation and safety findings. Complement Ther Med. 2018 Apr; 37:136-142. PMID: 29609926.
    View in: PubMed
  22. Vance MC, Bui E, Hoeppner SS, Kovachy B, Prescott J, Mischoulon D, Walton ZE, Dong M, Nadal MF, Worthington JJ, Hoge EA, Cassano P, Orr EH, Fava M, de Vivo I, Wong KK, Simon NM. Prospective association between major depressive disorder and leukocyte telomere length over two years. Psychoneuroendocrinology. 2018 Apr; 90:157-164. PMID: 29499556.
    View in: PubMed
  23. Fava M. The promise and challenges of drug repurposing in psychiatry. World Psychiatry. 2018 Feb; 17(1):28-29. PMID: 29352538.
    View in: PubMed
  24. Gomeni R, Bressolle-Gomeni F, Fava M. Is It Time for Going Beyond the P-Value Paradigm With the Estimation of the Probability of Clinical Benefit as a Criterion for Assessing the Outcomes of a Clinical Trial? A Case Study in Patients With Major Depressive Disorder. J Clin Pharmacol. 2018 Jun; 58(6):740-749. PMID: 29372561.
    View in: PubMed
  25. Gilman JM, Radoman M, Schuster RM, Pachas G, Azzouz N, Fava M, Evins AE. Anterior insula activation during inhibition to smoking cues is associated with ability to maintain tobacco abstinence. Addict Behav Rep. 2018 Jun; 7:40-46. PMID: 29450255.
    View in: PubMed
  26. Gao J, Cahill CM, Huang X, Roffman JL, Lamon-Fava S, Fava M, Mischoulon D, Rogers JT. S-Adenosyl Methionine and Transmethylation Pathways in Neuropsychiatric Diseases Throughout Life. Neurotherapeutics. 2018 Jan; 15(1):156-175. PMID: 29340929.
    View in: PubMed
  27. de Jong M, Peeters F, Gard T, Ashih H, Doorley J, Walker R, Rhoades L, Kulich RJ, Kueppenbender KD, Alpert JE, Hoge EA, Britton WB, Lazar SW, Fava M, Mischoulon D. A Randomized Controlled Pilot Study on Mindfulness-Based Cognitive Therapy for Unipolar Depression in Patients With Chronic Pain. J Clin Psychiatry. 2018 Jan/Feb; 79(1). PMID: 28252881.
    View in: PubMed
  28. Iovieno N, Shelton RC, Petrie SR, Cusin C, Fava M, Papakostas GI. Efficacy of Ziprasidone Augmentation of Escitalopram for Cognitive Symptoms of Major Depressive Disorder. J Clin Psychiatry. 2018 Jan/Feb; 79(1). PMID: 28749091.
    View in: PubMed
  29. Weiller E, Weiss C, Watling CP, Edge C, Hobart M, Eriksson H, Fava M. Functioning outcomes with adjunctive treatments for major depressive disorder: a systematic review of randomized placebo-controlled studies. Neuropsychiatr Dis Treat. 2018; 14:103-115. PMID: 29343962.
    View in: PubMed
  30. Janes AC, Gilman JM, Frederick BB, Radoman M, Pachas G, Fava M, Evins AE. Salience network coupling is linked to both tobacco smoking and symptoms of attention deficit hyperactivity disorder (ADHD). Drug Alcohol Depend. 2018 01 01; 182:93-97. PMID: 29175464.
    View in: PubMed
  31. Kim K, Kim SW, Myung W, Han CE, Fava M, Mischoulon D, Papakostas GI, Seo SW, Cho H, Seong JK, Jeon HJ. Reduced orbitofrontal-thalamic functional connectivity related to suicidal ideation in patients with major depressive disorder. Sci Rep. 2017 Nov 17; 7(1):15772. PMID: 29150619.
    View in: PubMed
  32. Yeung A, Wang F, Feng F, Zhang J, Cooper A, Hong L, Wang W, Griffiths K, Bennett K, Bennett A, Alpert J, Fava M. Outcomes of an online computerized cognitive behavioral treatment program for treating chinese patients with depression: A pilot study. Asian J Psychiatr. 2017 Nov 11. PMID: 29146042.
    View in: PubMed
  33. Mischoulon D, Hylek L, Yeung AS, Clain AJ, Baer L, Cusin C, Ionescu DF, Alpert JE, Soskin DP, Fava M. Corrigendum to "Randomized, proof-of-concept trial of low dose naltrexone for patients with breakthrough symptoms of major depressive disorder on antidepressants" [J. Affect. Disord. 208 (2017, Jan. 15) 6-14, doi: 10.1016/j.jad.2016.08.029, Epub 2016 Oct. 1]. J Affect Disord. 2018 02; 227:198. PMID: 29100152.
    View in: PubMed
  34. Choi KW, Na EJ, Hong JP, Cho MJ, Fava M, Mischoulon D, Cho H, Jeon HJ. Alcohol-induced disinhibition is associated with impulsivity, depression, and suicide attempt: A nationwide community sample of Korean adults. J Affect Disord. 2018 02; 227:323-329. PMID: 29132075.
    View in: PubMed
  35. Dodd S, Mitchell PB, Bauer M, Yatham L, Young AH, Kennedy SH, Williams L, Suppes T, Lopez Jaramillo C, Trivedi MH, Fava M, Rush AJ, McIntyre RS, Thase ME, Lam RW, Severus E, Kasper S, Berk M. Monitoring for antidepressant-associated adverse events in the treatment of patients with major depressive disorder: An international consensus statement. World J Biol Psychiatry. 2018 08; 19(5):330-348. PMID: 28984491.
    View in: PubMed
  36. Fava M, Freeman MP, Flynn M, Hoeppner BB, Shelton R, Iosifescu DV, Murrough JW, Mischoulon D, Cusin C, Rapaport M, Dunlop BW, Trivedi MH, Jha M, Sanacora G, Hermes G, Papakostas GI. Double-blind, proof-of-concept (POC) trial of Low-Field Magnetic Stimulation (LFMS) augmentation of antidepressant therapy in treatment-resistant depression (TRD). Brain Stimul. 2018 Jan - Feb; 11(1):75-84. PMID: 29030111.
    View in: PubMed
  37. Griffiths CEM, Fava M, Miller AH, Russell J, Ball SG, Xu W, Acharya N, Rapaport MH. Impact of Ixekizumab Treatment on Depressive Symptoms and Systemic Inflammation in Patients with Moderate-to-Severe Psoriasis: An Integrated Analysis of Three Phase 3 Clinical Studies. Psychother Psychosom. 2017; 86(5):260-267. PMID: 28903122.
    View in: PubMed
  38. Almeida JRC, Greenberg T, Lu H, Chase HW, Fournier JC, Cooper CM, Deckersbach T, Adams P, Carmody T, Fava M, Kurian B, McGrath PJ, McInnis MG, Oquendo MA, Parsey R, Weissman M, Trivedi M, Phillips ML. Test-retest reliability of cerebral blood flow in healthy individuals using arterial spin labeling: Findings from the EMBARC study. Magn Reson Imaging. 2018 01; 45:26-33. PMID: 28888770.
    View in: PubMed
  39. Bui E, Fava M. From depression to anxiety, and back. Acta Psychiatr Scand. 2017 10; 136(4):341-342. PMID: 28865404.
    View in: PubMed
  40. Lee HK, Kim JH, Fava M, Mischoulon D, Park JH, Shim EJ, Lee EH, Lee JH, Jeon HJ. Development and validation study of the Smartphone Overuse Screening Questionnaire. Psychiatry Res. 2017 11; 257:352-357. PMID: 28800515.
    View in: PubMed
  41. Janes AC, Gilman JM, Radoman M, Pachas G, Fava M, Evins AE. Revisiting the role of the insula and smoking cue-reactivity in relapse: A replication and extension of neuroimaging findings. Drug Alcohol Depend. 2017 10 01; 179:8-12. PMID: 28735078.
    View in: PubMed
  42. Heo JY, Yi H, Fava M, Mischoulon D, Kim K, Yoon S, Jeon HJ, Lee JE. Agoraphobia and Follicle-Stimulating Hormone Levels between Tamoxifen and Goserelin versus Tamoxifen Alone in Premenopausal Hormone Receptor-Positive Breast Cancer: A 12-Month Prospective Randomized Study. Psychiatry Investig. 2017 Jul; 14(4):491-498. PMID: 28845177.
    View in: PubMed
  43. Fava M. Lessons Learned From the VA Augmentation and Switching Treatments for Improving Depression Outcomes (VAST-D) Study. JAMA. 2017 07 11; 318(2):126-128. PMID: 28697241.
    View in: PubMed
  44. Kim DJ, Kim K, Lee HW, Hong JP, Cho MJ, Fava M, Mischoulon D, Heo JY, Jeon HJ. Internet Game Addiction, Depression, and Escape From Negative Emotions in Adulthood: A Nationwide Community Sample of Korea. J Nerv Ment Dis. 2017 Jul; 205(7):568-573. PMID: 28598958.
    View in: PubMed
  45. Yuan H, Mischoulon D, Fava M, Otto MW. Circulating microRNAs as biomarkers for depression: Many candidates, few finalists. J Affect Disord. 2018 06; 233:68-78. PMID: 28673667.
    View in: PubMed
  46. Perlman G, Bartlett E, DeLorenzo C, Weissman M, McGrath P, Ogden T, Jin T, Adams P, Trivedi M, Kurian B, Oquendo M, McInnis M, Weyandt S, Fava M, Cooper C, Malchow A, Parsey R. Cortical thickness is not associated with current depression in a clinical treatment study. Hum Brain Mapp. 2017 09; 38(9):4370-4385. PMID: 28594150.
    View in: PubMed
  47. Mathew SJ, Gueorguieva R, Brandt C, Fava M, Sanacora G. A Randomized, Double-Blind, Placebo-Controlled, Sequential Parallel Comparison Design Trial of Adjunctive Riluzole for Treatment-Resistant Major Depressive Disorder. Neuropsychopharmacology. 2017 Dec; 42(13):2567-2574. PMID: 28553836.
    View in: PubMed
  48. Yeung AS, Feng R, Kim DJH, Wayne PM, Yeh GY, Baer L, Lee OE, Denninger JW, Benson H, Fricchione GL, Alpert J, Fava M. A Pilot, Randomized Controlled Study of Tai Chi With Passive and Active Controls in the Treatment of Depressed Chinese Americans. J Clin Psychiatry. 2017 May; 78(5):e522-e528. PMID: 28570792.
    View in: PubMed
  49. Kim K, Lee H, Hong JP, Cho MJ, Fava M, Mischoulon D, Kim DJ, Jeon HJ. Poor sleep quality and suicide attempt among adults with internet addiction: A nationwide community sample of Korea. PLoS One. 2017; 12(4):e0174619. PMID: 28384238.
    View in: PubMed
  50. Freeman MP, Pooley J, Flynn MJ, Baer L, Mischoulon D, Mou D, Fava M. Guarding the Gate: Remote Structured Assessments to Enhance Enrollment Precision in Depression Trials. J Clin Psychopharmacol. 2017 Apr; 37(2):176-181. PMID: 28187008.
    View in: PubMed
  51. Fava M, Weiller E, Zhang P, Weiss C. Efficacy of Brexpiprazole as Adjunctive Treatment in Major Depressive Disorder With Irritability: Post Hoc Analysis of 2 Pivotal Clinical Studies. J Clin Psychopharmacol. 2017 Apr; 37(2):276-278. PMID: 28195853.
    View in: PubMed
  52. Mischoulon D, Shelton RC, Baer L, Bobo WV, Curren L, Fava M, Papakostas GI. Ziprasidone Augmentation of Escitalopram for Major Depressive Disorder: Cardiac, Endocrine, Metabolic, and Motoric Effects in a Randomized, Double-Blind, Placebo-Controlled Study. J Clin Psychiatry. 2017 04; 78(4):449-455. PMID: 27835715.
    View in: PubMed
  53. Lyall AE, Pasternak O, Robinson DG, Newell D, Trampush JW, Gallego JA, Fava M, Malhotra AK, Karlsgodt KH, Kubicki M, Szeszko PR. Greater extracellular free-water in first-episode psychosis predicts better neurocognitive functioning. Mol Psychiatry. 2018 Mar; 23(3):701-707. PMID: 28348381.
    View in: PubMed
  54. Swann AC, Fava M, Tsai J, Mao Y, Pikalov A, Loebel A. Lurasidone for major depressive disorder with mixed features and irritability: a post-hoc analysis. CNS Spectr. 2017 Apr; 22(2):228-235. PMID: 28300012.
    View in: PubMed
  55. Stauffer VL, Liu P, Goldberger C, Marangell LB, Nelson C, Gorwood P, Fava M. Is the Noradrenergic Symptom Cluster a Valid Construct in Adjunctive Treatment of Major Depressive Disorder? J Clin Psychiatry. 2017 03; 78(3):317-323. PMID: 27685842.
    View in: PubMed
  56. Stahl SM, Morrissette DA, Faedda G, Fava M, Goldberg JF, Keck PE, Lee Y, Malhi G, Marangoni C, McElroy SL, Ostacher M, Rosenblat JD, Solé E, Suppes T, Takeshima M, Thase ME, Vieta E, Young A, Zimmerman M, McIntyre RS. Guidelines for the recognition and management of mixed depression. CNS Spectr. 2017 Apr; 22(2):203-219. PMID: 28421980.
    View in: PubMed
  57. Petkova E, Ogden RT, Tarpey T, Ciarleglio A, Jiang B, Su Z, Carmody T, Adams P, Kraemer HC, Grannemann BD, Oquendo MA, Parsey R, Weissman M, McGrath PJ, Fava M, Trivedi MH. Statistical Analysis Plan for Stage 1 EMBARC (Establishing Moderators and Biosignatures of Antidepressant Response for Clinical Care) Study. Contemp Clin Trials Commun. 2017 Jun; 6:22-30. PMID: 28670629.
    View in: PubMed
  58. Freeman MP, Fisher L, Clain A, Rabbitt R, Pooley J, Baer L, Fava M. Differentiating residual symptoms of depression from adverse events among patients initiating treatment with an antidepressant. Ann Clin Psychiatry. 2017 02; 29(1):28-34. PMID: 28207913.
    View in: PubMed
  59. Delaparte L, Yeh FC, Adams P, Malchow A, Trivedi MH, Oquendo MA, Deckersbach T, Ogden T, Pizzagalli DA, Fava M, Cooper C, McInnis M, Kurian BT, Weissman MM, McGrath PJ, Klein DN, Parsey RV, DeLorenzo C. A comparison of structural connectivity in anxious depression versus non-anxious depression. J Psychiatr Res. 2017 Jun; 89:38-47. PMID: 28157545.
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  60. Rutrick D, Stein DJ, Subramanian G, Smith B, Fava M, Hasler G, Cha JH, Gasparini F, Donchev T, Ocwieja M, Johns D, Gomez-Mancilla B. Mavoglurant Augmentation in OCD Patients Resistant to Selective Serotonin Reuptake Inhibitors: A Proof-of-Concept, Randomized, Placebo-Controlled, Phase 2 Study. Adv Ther. 2017 Feb; 34(2):524-541. PMID: 28044255.
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  62. Tenke CE, Kayser J, Pechtel P, Webb CA, Dillon DG, Goer F, Murray L, Deldin P, Kurian BT, McGrath PJ, Parsey R, Trivedi M, Fava M, Weissman MM, McInnis M, Abraham K, E Alvarenga J, Alschuler DM, Cooper C, Pizzagalli DA, Bruder GE. Demonstrating test-retest reliability of electrophysiological measures for healthy adults in a multisite study of biomarkers of antidepressant treatment response. Psychophysiology. 2017 01; 54(1):34-50. PMID: 28000259.
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  63. Fava M, Okame T, Matsushima Y, Perry P, Weiller E, Baker RA. Switching from Inadequate Adjunctive or Combination Treatment Options to Brexpiprazole Adjunctive to Antidepressant: An Open-Label Study on the Effects on Depressive Symptoms and Cognitive and Physical Functioning. Int J Neuropsychopharmacol. 2017 01 01; 20(1):22-30. PMID: 27784751.
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  64. Baek JH, Kim JH, Kim BN, Park SJ, Fava M, Mischoulon D, Lee D, Jeon HJ. Comparisons of Subthreshold Versus Full Posttraumatic Stress Disorder Distinguished by Subjective Functional Impairment Among Train Drivers: A Population-Based Nationwide Study in South Korea. Psychiatry Investig. 2017 Jan; 14(1):1-7. PMID: 28096868.
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  65. Heo JY, Kim K, Fava M, Mischoulon D, Papakostas GI, Kim MJ, Kim DJ, Chang KJ, Oh Y, Yu BH, Jeon HJ. Effects of smartphone use with and without blue light at night in healthy adults: A randomized, double-blind, cross-over, placebo-controlled comparison. J Psychiatr Res. 2017 04; 87:61-70. PMID: 28017916.
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  66. Fournier JC, Chase HW, Greenberg T, Etkin A, Almeida JR, Stiffler R, Deckersbach T, Weyandt S, Cooper C, Toups M, Carmody T, Kurian B, Peltier S, Adams P, McInnis MG, Oquendo MA, McGrath PJ, Fava M, Weissman M, Parsey R, Trivedi MH, Phillips ML. Neuroticism and Individual Differences in Neural Function in Unmedicated Major Depression: Findings from the EMBARC Study. Biol Psychiatry Cogn Neurosci Neuroimaging. 2017 Mar; 2(2):138-148. PMID: 28983519.
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  67. Harel EV, Tennyson RL, Fava M, Bar M. Linking major depression and the neural substrates of associative processing. Cogn Affect Behav Neurosci. 2016 12; 16(6):1017-1026. PMID: 27553369.
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  68. Fava M, Ménard F, Davidsen CK, Baker RA. Adjunctive Brexpiprazole in Patients With Major Depressive Disorder and Irritability: An Exploratory Study. J Clin Psychiatry. 2016 Dec; 77(12):1695-1701. PMID: 27379823.
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  69. Jeon HJ, Woo JM, Kim HJ, Fava M, Mischoulon D, Cho SJ, Chang SM, Park DH, Kim JW, Yoo I, Heo JY, Hong JP. Gender Differences in Somatic Symptoms and Current Suicidal Risk in Outpatients with Major Depressive Disorder. Psychiatry Investig. 2016 Nov; 13(6):609-615. PMID: 27909451.
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  70. Ionescu DF, Shelton RC, Baer L, Meade KH, Swee MB, Fava M, Papakostas GI. Ziprasidone augmentation for anxious depression. Int Clin Psychopharmacol. 2016 11; 31(6):341-6. PMID: 27306192; PMCID: PMC5039050 [Available on 11/01/17].
  71. Chen JA, Shapero BG, Trinh NT, Chang TE, Parkin S, Alpert JE, Fava M, Yeung AS. Association Between Stigma and Depression Outcomes Among Chinese Immigrants in a Primary Care Setting. J Clin Psychiatry. 2016 Oct; 77(10):e1287-e1292. PMID: 27631145.
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  72. Mischoulon D, Hylek L, Yeung AS, Clain AJ, Baer L, Cusin C, Ionescu DF, Alpert JE, Soskin DP, Fava M. Randomized, proof-of-concept trial of low dose naltrexone for patients with breakthrough symptoms of major depressive disorder on antidepressants. J Affect Disord. 2017 01 15; 208:6-14. PMID: 27736689.
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  73. Cassano P, Bui E, Rogers AH, Walton ZE, Ross R, Zeng M, Nadal-Vicens M, Mischoulon D, Baker AW, Keshaviah A, Worthington J, Hoge EA, Alpert J, Fava M, Wong KK, Simon NM. Inflammatory cytokines in major depressive disorder: A case-control study. Aust N Z J Psychiatry. 2017 Jan; 51(1):23-31. PMID: 27313138.
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  74. Ma Y, Yeung A, Yang AC, Peng CK, Clain A, Alpert J, Fava M, Yeung AS. The Effects of Tai Chi on Sleep Quality in Chinese American Patients With Major Depressive Disorder: A Pilot Study. Behav Sleep Med. 2018 Jul-Aug; 16(4):398-411. PMID: 27676270.
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  75. Otte C, Gold SM, Penninx BW, Pariante CM, Etkin A, Fava M, Mohr DC, Schatzberg AF. Major depressive disorder. Nat Rev Dis Primers. 2016 09 15; 2:16065. PMID: 27629598.
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  76. Harper DG, Jensen JE, Ravichandran C, Perlis RH, Fava M, Renshaw PF, Iosifescu DV. Tissue Type-Specific Bioenergetic Abnormalities in Adults with Major Depression. Neuropsychopharmacology. 2017 Mar; 42(4):876-885. PMID: 27585738.
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  77. Chang KJ, Kim K, Fava M, Mischoulon D, Hong JP, Kim DJ, Heo JY, Choi H, Jeon HJ. Cross-national differences in hypochondriasis symptoms between Korean and American outpatients with major depressive disorder. Psychiatry Res. 2016 11 30; 245:127-132. PMID: 27541348.
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  78. Yeung A, Martinson MA, Baer L, Chen J, Clain A, Williams A, Chang TE, Trinh NH, Alpert JE, Fava M. The Effectiveness of Telepsychiatry-Based Culturally Sensitive Collaborative Treatment for Depressed Chinese American Immigrants: A Randomized Controlled Trial. J Clin Psychiatry. 2016 08; 77(8):e996-e1002. PMID: 27561153.
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  79. Mischoulon D, Zajecka J, Freeman MP, Fava M. Does folic acid interfere with lamotrigine? Lancet Psychiatry. 2016 Aug; 3(8):704-5. PMID: 27475760.
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  80. Yoo HJ, Hong JP, Cho MJ, Fava M, Mischoulon D, Heo JY, Kim K, Jeon HJ. Lifetime suicidal ideation and attempt in adults with full major depressive disorder versus sustained depressed mood. J Affect Disord. 2016 10; 203:275-280. PMID: 27314814.
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  81. Ionescu DF, Swee MB, Pavone KJ, Taylor N, Akeju O, Baer L, Nyer M, Cassano P, Mischoulon D, Alpert JE, Brown EN, Nock MK, Fava M, Cusin C. Rapid and Sustained Reductions in Current Suicidal Ideation Following Repeated Doses of Intravenous Ketamine: Secondary Analysis of an Open-Label Study. J Clin Psychiatry. 2016 06; 77(6):e719-25. PMID: 27232360.
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  82. Baek JH, Kim HJ, Fava M, Mischoulon D, Papakostas GI, Nierenberg A, Heo JY, Jeon HJ. Reduced Venous Blood Basophil Count and Anxious Depression in Patients with Major Depressive Disorder. Psychiatry Investig. 2016 May; 13(3):321-6. PMID: 27247599; PMCID: PMC4878967.
  83. Zajecka JM, Fava M, Shelton RC, Barrentine LW, Young P, Papakostas GI. Long-term efficacy, safety, and tolerability of L-methylfolate calcium 15 mg as adjunctive therapy with selective serotonin reuptake inhibitors: a 12-month, open-label study following a placebo-controlled acute study. J Clin Psychiatry. 2016 May; 77(5):654-60. PMID: 27035404.
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  86. Otto MW, Lee J, Hofmann SG, Hearon BA, Smits JA, Rosenfield D, Fava M, Wright JH. Examining the efficacy of d-cycloserine to augment therapeutic learning in depression. Contemp Clin Trials. 2016 05; 48:146-52. PMID: 27094721.
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  87. Singh JB, Fedgchin M, Daly EJ, De Boer P, Cooper K, Lim P, Pinter C, Murrough JW, Sanacora G, Shelton RC, Kurian B, Winokur A, Fava M, Manji H, Drevets WC, Van Nueten L. A Double-Blind, Randomized, Placebo-Controlled, Dose-Frequency Study of Intravenous Ketamine in Patients With Treatment-Resistant Depression. Am J Psychiatry. 2016 Aug 01; 173(8):816-26. PMID: 27056608.
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  88. Isitt JJ, Nadipelli VR, Kouassi A, Fava M, Heidbreder C. Health-related quality of life in acute schizophrenia patients treated with RBP-7000 once monthly risperidone: An 8-week, randomized, double-blind, placebo-controlled, multicenter phase 3 study. Schizophr Res. 2016 07; 174(1-3):126-131. PMID: 27066860.
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  89. Nasser AF, Henderson DC, Fava M, Fudala PJ, Twumasi-Ankrah P, Kouassi A, Heidbreder C. Efficacy, Safety, and Tolerability of RBP-7000 Once-Monthly Risperidone for the Treatment of Acute Schizophrenia: An 8-Week, Randomized, Double-Blind, Placebo-Controlled, Multicenter Phase 3 Study. J Clin Psychopharmacol. 2016 Apr; 36(2):130-40. PMID: 26862829.
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  90. Petryshen TL, Lewis MC, Dennehy KA, Garza JC, Fava M. Antidepressant-like effect of low dose ketamine and scopolamine co-treatment in mice. Neurosci Lett. 2016 05 04; 620:70-3. PMID: 27033002.
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  91. Trivedi MH, McGrath PJ, Fava M, Parsey RV, Kurian BT, Phillips ML, Oquendo MA, Bruder G, Pizzagalli D, Toups M, Cooper C, Adams P, Weyandt S, Morris DW, Grannemann BD, Ogden RT, Buckner R, McInnis M, Kraemer HC, Petkova E, Carmody TJ, Weissman MM. Establishing moderators and biosignatures of antidepressant response in clinical care (EMBARC): Rationale and design. J Psychiatr Res. 2016 07; 78:11-23. PMID: 27038550.
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  92. Durgam S, Earley W, Guo H, Li D, Németh G, Laszlovszky I, Fava M, Montgomery SA. Efficacy and safety of adjunctive cariprazine in inadequate responders to antidepressants: a randomized, double-blind, placebo-controlled study in adult patients with major depressive disorder. J Clin Psychiatry. 2016 Mar; 77(3):371-8. PMID: 27046309.
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  93. Freeman MP, Fava M, Gommoll C, Chen C, Greenberg WM, Ruth A. Effects of levomilnacipran ER on fatigue symptoms associated with major depressive disorder. Int Clin Psychopharmacol. 2016 Mar; 31(2):100-9. PMID: 26584326; PMCID: PMC4736297.
  94. Fava M, Memisoglu A, Thase ME, Bodkin JA, Trivedi MH, de Somer M, Du Y, Leigh-Pemberton R, DiPetrillo L, Silverman B, Ehrich E. Opioid Modulation With Buprenorphine/Samidorphan as Adjunctive Treatment for Inadequate Response to Antidepressants: A Randomized Double-Blind Placebo-Controlled Trial. Am J Psychiatry. 2016 May 01; 173(5):499-508. PMID: 26869247.
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  96. Huz I, Nyer M, Dickson C, Farabaugh A, Alpert J, Fava M, Baer L. Obsessive-Compulsive Symptoms as a Risk Factor for Suicidality in U.S. College Students. J Adolesc Health. 2016 Apr; 58(4):481-484. PMID: 26803200.
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  97. Iovieno N, Nierenberg AA, Parkin SR, Hyung Kim DJ, Walker RS, Fava M, Papakostas GI. Relationship between placebo response rate and clinical trial outcome in bipolar depression. J Psychiatr Res. 2016 Mar; 74:38-44. PMID: 26736040.
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  98. Fava M, Johe K, Ereshefsky L, Gertsik LG, English BA, Bilello JA, Thurmond LM, Johnstone J, Dickerson BC, Makris N, Hoeppner BB, Flynn M, Mischoulon D, Kinrys G, Freeman MP. A Phase 1B, randomized, double blind, placebo controlled, multiple-dose escalation study of NSI-189 phosphate, a neurogenic compound, in depressed patients. Mol Psychiatry. 2016 10; 21(10):1372-80. PMID: 26643541.
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  105. Fisher LB, Fava M, Doros GD, Alpert JE, Henry M, Huz I, Freeman MP. The Role of Anger/Hostility in Treatment-Resistant Depression: A Secondary Analysis From the ADAPT-A Study. J Nerv Ment Dis. 2015 Oct; 203(10):762-8. PMID: 26348584.
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  107. Mischoulon D, De Jong MF, Vitolo OV, Cusin C, Dording CM, Yeung AS, Durham K, Parkin SR, Fava M, Dougherty DD. Efficacy and safety of a form of cranial electrical stimulation (CES) as an add-on intervention for treatment-resistant major depressive disorder: A three week double blind pilot study. J Psychiatr Res. 2015 Nov; 70:98-105. PMID: 26424428.
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  108. Baek JH, Heo JY, Fava M, Mischoulon D, Nierenberg A, Hong JP, Roh S, Jeon HJ. Anxiety symptoms are linked to new-onset suicidal ideation after six months of follow-up in outpatients with major depressive disorder. J Affect Disord. 2015 Nov 15; 187:183-7. PMID: 26342171.
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  110. Trinh NH, Hails K, Flaherty K, Chang T, Fava M, Yeung A. Lessons Learned: Implementation of a Culturally Focused Psychiatric Consultation Service for Latino Americans and Asian Americans. J Health Care Poor Underserved. 2015 Aug; 26(3):792-801. PMID: 26320914.
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  112. Baek JH, Park JI, Ahn J, Roh SW, Heo JY, Fava M, Mischoulon D, Jeon HJ. Review of Suicide Prevention Programs: Massachusetts, United States, in Comparison with Seoul. Psychiatry Investig. 2015 Jul; 12(3):281-7. PMID: 26207119; PMCID: PMC4504908.
  113. Goldberg JF, Freeman MP, Balon R, Citrome L, Thase ME, Kane JM, Fava M. THE AMERICAN SOCIETY OF CLINICAL PSYCHOPHARMACOLOGY SURVEY OF PSYCHOPHARMACOLOGISTS' PRACTICE PATTERNS FOR THE TREATMENT OF MOOD DISORDERS. Depress Anxiety. 2015 Aug; 32(8):605-13. PMID: 26129956.
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  116. Webb CA, Dillon DG, Pechtel P, Goer FK, Murray L, Huys QJ, Fava M, McGrath PJ, Weissman M, Parsey R, Kurian BT, Adams P, Weyandt S, Trombello JM, Grannemann B, Cooper CM, Deldin P, Tenke C, Trivedi M, Bruder G, Pizzagalli DA. Neural Correlates of Three Promising Endophenotypes of Depression: Evidence from the EMBARC Study. Neuropsychopharmacology. 2016 Jan; 41(2):454-63. PMID: 26068725.
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  121. Targum SD, Wedel PC, Fava M. Changes in cognitive symptoms after a buspirone-melatonin combination treatment for Major Depressive Disorder. J Psychiatr Res. 2015 Sep; 68:392-6. PMID: 26025562.
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  123. Farabaugh A, Fisher L, Nyer M, Holt D, Cohen M, Baer L, Shapero BG, Huz I, Cardoos A, Fava M, Alpert JE. Similar changes in cognitions following cognitive-behavioral therapy or escitalopram for major depressive disorder: Implications for mechanisms of change. Ann Clin Psychiatry. 2015 May; 27(2):118-26. PMID: 25954938.
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  125. Brennan FX, Gardner KR, Lombard J, Perlis RH, Fava M, Harris HW, Scott R. A Naturalistic Study of the Effectiveness of Pharmacogenetic Testing to Guide Treatment in Psychiatric Patients With Mood and Anxiety Disorders. Prim Care Companion CNS Disord. 2015; 17(2). PMID: 26445691; PMCID: PMC4560190.
  126. Dording CM, Schettler PJ, Dalton ED, Parkin SR, Walker RS, Fehling KB, Fava M, Mischoulon D. A double-blind placebo-controlled trial of maca root as treatment for antidepressant-induced sexual dysfunction in women. Evid Based Complement Alternat Med. 2015; 2015:949036. PMID: 25954318; PMCID: PMC4411442.
  127. Simon NM, Walton ZE, Bui E, Prescott J, Hoge E, Keshaviah A, Schwarz N, Dryman T, Ojserkis RA, Kovachy B, Mischoulon D, Worthington J, De Vivo I, Fava M, Wong KK. Telomere length and telomerase in a well-characterized sample of individuals with major depressive disorder compared to controls. Psychoneuroendocrinology. 2015 Aug; 58:9-22. PMID: 25932992; PMCID: PMC4461511.
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  131. Nierenberg AA, Østergaard SD, Iovieno N, Walker RS, Fava M, Papakostas GI. Predictors of placebo response in bipolar depression. Int Clin Psychopharmacol. 2015 Mar; 30(2):59-66. PMID: 25438027.
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  132. Janes AC, Pedrelli P, Whitton AE, Pechtel P, Douglas S, Martinson MA, Huz I, Fava M, Pizzagalli DA, Evins AE. Reward Responsiveness Varies by Smoking Status in Women with a History of Major Depressive Disorder. Neuropsychopharmacology. 2015 Jul; 40(8):1940-6. PMID: 25662839; PMCID: PMC4839517.
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  136. Ehrich E, Turncliff R, Du Y, Leigh-Pemberton R, Fernandez E, Jones R, Fava M. Evaluation of opioid modulation in major depressive disorder. Neuropsychopharmacology. 2015 May; 40(6):1448-55. PMID: 25518754; PMCID: PMC4397403.
  137. Chen JA, Vijapura S, Papakostas GI, Parkin SR, Kim DJ, Cusin C, Baer L, Clain AJ, Fava M, Mischoulon D. Association between physician beliefs regarding assigned treatment and clinical response: re-analysis of data from the Hypericum Depression Trial Study Group. Asian J Psychiatr. 2015 Feb; 13:23-9. PMID: 25544195; PMCID: PMC4518843.
  138. Jeon HJ, Lee C, Fava M, Mischoulon D, Shim EJ, Heo JY, Choi H, Park JH. Childhood trauma, parental death, and their co-occurrence in relation to current suicidality risk in adults: a nationwide community sample of Korea. J Nerv Ment Dis. 2014 Dec; 202(12):870-6. PMID: 25370752.
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  139. Jeon HJ, Kim JH, Kim BN, Park SJ, Fava M, Mischoulon D, Kang EH, Roh S, Lee D. Sleep quality, posttraumatic stress, depression, and human errors in train drivers: a population-based nationwide study in South Korea. Sleep. 2014 Dec 01; 37(12):1969-75. PMID: 25325495; PMCID: PMC4548517.
  140. Trinh NH, Hagan PN, Flaherty K, Traeger LN, Inamori A, Brill CD, Hails K, Chang TE, Bedoya CA, Fava M, Yeung A. Evaluating patient acceptability of a culturally focused psychiatric consultation intervention for Latino Americans with depression. J Immigr Minor Health. 2014 Dec; 16(6):1271-7. PMID: 24097287.
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  146. Yeung A, Slipp LE, Niles H, Jacquart J, Chow CL, Fava M, Denninger JW, Benson H, Fricchione GL. Effectiveness of the relaxation response-based group intervention for treating depressed chinese american immigrants: a pilot study. Int J Environ Res Public Health. 2014 Sep 05; 11(9):9186-201. PMID: 25198683; PMCID: PMC4199014.
  147. Thase ME, Fava M, Nierenberg AA. Depression: addressing partial response after first-line antidepressant treatment. J Clin Psychiatry. 2014 Sep; 75(9):978-80. PMID: 25295423.
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  149. Baek JH, Kang ES, Fava M, Mischoulon D, Nierenberg AA, Lee D, Heo JY, Jeon HJ. Thyroid stimulating hormone and serum, plasma, and platelet brain-derived neurotrophic factor during a 3-month follow-up in patients with major depressive disorder. J Affect Disord. 2014 Dec; 169:112-7. PMID: 25189990.
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  154. Calabrese JR, Fava M, Garibaldi G, Grunze H, Krystal AD, Laughren T, Macfadden W, Marin R, Nierenberg AA, Tohen M. Methodological approaches and magnitude of the clinical unmet need associated with amotivation in mood disorders. J Affect Disord. 2014 Oct; 168:439-51. PMID: 25113957.
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  156. Targum SD, Burch DJ, Asgharnejad M, Petersen T, Gomeni R, Fava M. Use of band-pass filter analysis to evaluate outcomes in an antidepressant trial for treatment resistant patients. Eur Neuropsychopharmacol. 2014 Aug; 24(8):1188-95. PMID: 25012515.
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  157. Jeon HJ, Park JI, Fava M, Mischoulon D, Sohn JH, Seong S, Park JE, Yoo I, Cho MJ. Feelings of worthlessness, traumatic experience, and their comorbidity in relation to lifetime suicide attempt in community adults with major depressive disorder. J Affect Disord. 2014 Sep; 166:206-12. PMID: 25012433.
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  159. Fagerness J, Fonseca E, Hess GP, Scott R, Gardner KR, Koffler M, Fava M, Perlis R, Brennan FX, Lombard J. Pharmacogenetic-guided psychiatric intervention associated with increased adherence and cost savings. Am J Manag Care. 2014 May; 20(5):e146-56. PMID: 25326929.
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  161. Ostergaard SD, Bech P, Trivedi MH, Wisniewski SR, Rush AJ, Fava M. Brief, unidimensional melancholia rating scales are highly sensitive to the effect of citalopram and may have biological validity: implications for the research domain criteria (RDoC). J Affect Disord. 2014 Jul; 163:18-24. PMID: 24836083.
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  164. Jeon HJ, Woo JM, Lee SH, Kim EJ, Chung S, Ha JH, Fava M, Mischoulon D, Kim JH, Heo JY, Yu BH. Improvement in subjective and objective neurocognitive functions in patients with major depressive disorder: a 12-week, multicenter, randomized trial of tianeptine versus escitalopram, the CAMPION study. J Clin Psychopharmacol. 2014 Apr; 34(2):218-25. PMID: 24525660.
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  166. Liverant GI, Sloan DM, Pizzagalli DA, Harte CB, Kamholz BW, Rosebrock LE, Cohen AL, Fava M, Kaplan GB. Associations among smoking, anhedonia, and reward learning in depression. Behav Ther. 2014 Sep; 45(5):651-63. PMID: 25022776; PMCID: PMC4446716.
  167. Baek JH, Kang ES, Fava M, Mischoulon D, Nierenberg AA, Yu BH, Lee D, Jeon HJ. Serum lipids, recent suicide attempt and recent suicide status in patients with major depressive disorder. Prog Neuropsychopharmacol Biol Psychiatry. 2014 Jun 03; 51:113-8. PMID: 24495778.
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  172. Toups MS, Myers AK, Wisniewski SR, Kurian B, Morris DW, Rush AJ, Fava M, Trivedi MH. Relationship between obesity and depression: characteristics and treatment outcomes with antidepressant medication. Psychosom Med. 2013 Nov-Dec; 75(9):863-72. PMID: 24163386; PMCID: PMC3905462.
  173. Rothschild AJ, Raskin J, Wang CN, Marangell LB, Fava M. The relationship between change in apathy and changes in cognition and functional outcomes in currently non-depressed SSRI-treated patients with major depressive disorder. Compr Psychiatry. 2014 Jan; 55(1):1-10. PMID: 24268564.
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  175. Freeman MP, Walker R, Laughren TP, Miller KK, Fava M. Female reproductive life cycle and hormones: methodology to improve clinical trials. J Clin Psychiatry. 2013 Oct; 74(10):1018-21. PMID: 24229755; PMCID: PMC4096821.
  176. Kim B, Kang ES, Fava M, Mischoulon D, Soskin D, Yu BH, Lee D, Lee DY, Park HD, Jeon HJ. Follicle-stimulating hormone (FSH), current suicidal ideation and attempt in female patients with major depressive disorder. Psychiatry Res. 2013 Dec 30; 210(3):951-6. PMID: 24080256.
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  177. Gomeni R, Fava M. Amyotrophic lateral sclerosis disease progression model. Amyotroph Lateral Scler Frontotemporal Degener. 2014 Mar; 15(1-2):119-29. PMID: 24070404.
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  178. Desseilles M, Witte J, Chang TE, Iovieno N, Dording C, Ashih H, Nyer M, Freeman MP, Fava M, Mischoulon D. Massachusetts General Hospital SAFER criteria for clinical trials and research. Harv Rev Psychiatry. 2013 Sep-Oct; 21(5):269-74. PMID: 24651559.
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  179. Matthews JD, Siefert CJ, Blais MA, Park LT, Siefert CJ, Welch CA, Dubois CM, van Nieuwenhuizen AO, Rooney KO, Seabrook RC, Durham LE, Adams HC, Fava M. A double-blind, placebo-controlled study of the impact of galantamine on anterograde memory impairment during electroconvulsive therapy. J ECT. 2013 Sep; 29(3):170-8. PMID: 23519225.
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  180. Dording C, Cassiello C, King F, Pencina M, Fava M, Mischoulon D. The effects of aripiprazole on the subscales of the Kellner Symptom Questionnaire in treatment resistant depression. Int Clin Psychopharmacol. 2013 Sep; 28(5):238-44. PMID: 23764521.
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  182. Soskin DP, Holt DJ, Sacco GR, Fava M. Incentive salience: novel treatment strategies for major depression. CNS Spectr. 2013 Dec; 18(6):307-14. PMID: 23903027.
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  183. Pedrelli P, Borsari B, Palm KM, Dalton E, Fava M. Combined MI + CBT for Depressive Symptoms and Binge Drinking Among Young Adults: Two Case Studies. J Cogn Psychother. 2013 Aug 01; 27(3):235-257. PMID: 25170188.
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  184. Fava M. How can we make measures of psychotic depression symptoms more clinically useful? Acta Psychiatr Scand. 2014 Mar; 129(3):161-2. PMID: 23869739.
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  185. Borsook D, Becerra L, Fava M. Use of functional imaging across clinical phases in CNS drug development. Transl Psychiatry. 2013 Jul 16; 3:e282. PMID: 23860483.
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  186. Jeon HJ, Hong JP, Fava M, Mischoulon D, Nyer M, Inamori A, Sohn JH, Seong S, Cho MJ. Childhood parental death and lifetime suicide attempt of the opposite-gender offspring in a nationwide community sample of Korea. Suicide Life Threat Behav. 2013 Dec; 43(6):598-610. PMID: 23834109.
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  189. Nyer M, Farabaugh A, Fehling K, Soskin D, Holt D, Papakostas GI, Pedrelli P, Fava M, Pisoni A, Vitolo O, Mischoulon D. Relationship between sleep disturbance and depression, anxiety, and functioning in college students. Depress Anxiety. 2013 Sep; 30(9):873-80. PMID: 23681944; PMCID: PMC3791314.
  190. Lu Y, Dipierro M, Chen L, Chin R, Fava M, Yeung A. The evaluation of a culturally appropriate, community-based lifestyle intervention program for elderly Chinese immigrants with chronic diseases: a pilot study. J Public Health (Oxf). 2014 Mar; 36(1):149-55. PMID: 23596196.
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  191. Yeung A, Slipp LE, Jacquart J, Fava M, Denninger JW, Benson H, Fricchione GL. The treatment of depressed chinese americans using qigong in a health care setting: a pilot study. Evid Based Complement Alternat Med. 2013; 2013:168784. PMID: 23690836; PMCID: PMC3639645.
  192. Ratti E, Bettica P, Alexander R, Archer G, Carpenter D, Evoniuk G, Gomeni R, Lawson E, Lopez M, Millns H, Rabiner EA, Trist D, Trower M, Zamuner S, Krishnan R, Fava M. Full central neurokinin-1 receptor blockade is required for efficacy in depression: evidence from orvepitant clinical studies. J Psychopharmacol. 2013 May; 27(5):424-34. PMID: 23539641.
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  193. Cassano P, Chang T, Trinh NH, Baer L, Fava M, Mischoulon D. Differential impact of isolated psychotic symptoms on treatment outcome of major depressive disorder in the STAR*D cohort of Whites, Blacks and Latinos. J Affect Disord. 2013 Sep 05; 150(2):578-84. PMID: 23489398.
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  194. Cardoos A, Inamori A, Sanacora G, Fava M, Mischoulon D. Delayed amnesic syndrome after riluzole use in major depressive disorder: a case report. Psychosomatics. 2013 Sep-Oct; 54(5):488-92. PMID: 23473447; PMCID: PMC3681895.
  195. Jeon HJ, Peng D, Chua HC, Srisurapanont M, Fava M, Bae JN, Man Chang S, Hong JP. Melancholic features and hostility are associated with suicidality risk in Asian patients with major depressive disorder. J Affect Disord. 2013 Jun; 148(2-3):368-74. PMID: 23414572.
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  196. Vitali M, Tedeschini E, Mistretta M, Fehling K, Aceti F, Ceccanti M, Fava M. Adjunctive pregabalin in partial responders with major depressive disorder and residual anxiety. J Clin Psychopharmacol. 2013 Feb; 33(1):95-8. PMID: 23277244.
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  197. Kornstein SG, Toups M, Rush AJ, Wisniewski SR, Thase ME, Luther J, Warden D, Fava M, Trivedi MH. Do menopausal status and use of hormone therapy affect antidepressant treatment response? Findings from the Sequenced Treatment Alternatives to Relieve Depression (STAR*D) study. J Womens Health (Larchmt). 2013 Feb; 22(2):121-31. PMID: 23398127; PMCID: PMC3613168.
  198. Nyer M, Holt DJ, Pedrelli P, Fava M, Ameral V, Cassiello CF, Nock MK, Ross M, Hutchinson D, Farabaugh A. Factors that distinguish college students with depressive symptoms with and without suicidal thoughts. Ann Clin Psychiatry. 2013 Feb; 25(1):41-9. PMID: 23376869; PMCID: PMC3791316.
  199. Dording CM, LaRocca RA, Hails KA, Vitolo OV, Wisniewski SR, Balasubramani GK, Trivedi M, Fava M, Mischoulon D. The effect of sildenafil on quality of life. Ann Clin Psychiatry. 2013 Feb; 25(1):3-10. PMID: 23376864.
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  201. Doros G, Pencina M, Rybin D, Meisner A, Fava M. A repeated measures model for analysis of continuous outcomes in sequential parallel comparison design studies. Stat Med. 2013 Jul 20; 32(16):2767-89. PMID: 23355369.
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  202. Papakostas GI, Vitolo OV, Ishak WW, Rapaport MH, Zajecka JM, Kinrys G, Mischoulon D, Lipkin SH, Hails KA, Abrams J, Ward SG, Meisner A, Schoenfeld DA, Shelton RC, Winokur A, Okasha MS, Bari MA, Fava M. A 12-week, randomized, double-blind, placebo-controlled, sequential parallel comparison trial of ziprasidone as monotherapy for major depressive disorder. J Clin Psychiatry. 2012 Dec; 73(12):1541-7. PMID: 23290327.
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  204. Witte J, Bentley K, Evins AE, Clain AJ, Baer L, Pedrelli P, Fava M, Mischoulon D. A randomized, controlled, pilot study of acamprosate added to escitalopram in adults with major depressive disorder and alcohol use disorder. J Clin Psychopharmacol. 2012 Dec; 32(6):787-96. PMID: 23131884; PMCID: PMC3794470.
  205. Gilman SE, Breslau J, Trinh NH, Fava M, Murphy JM, Smoller JW. Epidemiologic evidence concerning the bereavement exclusion in major depression. Arch Gen Psychiatry. 2012 Nov; 69(11):1179-80; author reply 1180-1. PMID: 23117639.
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  206. Yeung A, Lepoutre V, Wayne P, Yeh G, Slipp LE, Fava M, Denninger JW, Benson H, Fricchione GL. Tai chi treatment for depression in Chinese Americans: a pilot study. Am J Phys Med Rehabil. 2012 Oct; 91(10):863-70. PMID: 22790795.
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  207. Gallagher PJ, Castro V, Fava M, Weilburg JB, Murphy SN, Gainer VS, Churchill SE, Kohane IS, Iosifescu DV, Smoller JW, Perlis RH. Antidepressant response in patients with major depression exposed to NSAIDs: a pharmacovigilance study. Am J Psychiatry. 2012 Oct; 169(10):1065-72. PMID: 23032386; PMCID: PMC3787520.
  208. Fava M, Targum SD, Nierenberg AA, Bleicher LS, Carter TA, Wedel PC, Hen R, Gage FH, Barlow C. An exploratory study of combination buspirone and melatonin SR in major depressive disorder (MDD): a possible role for neurogenesis in drug discovery. J Psychiatr Res. 2012 Dec; 46(12):1553-63. PMID: 22998742.
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  209. Perlis RH, Uher R, Perroud N, Fava M. Do suicidal thoughts or behaviors recur during a second antidepressant treatment trial? J Clin Psychiatry. 2012 Nov; 73(11):1439-42. PMID: 23059018; PMCID: PMC3787539.
  210. Nierenberg AA, Bentley KH, Farabaugh AH, Fava M, Deckersbach T. The absence of depressive symptoms is not the presence of wellness: validation of the Clinical Positive Affect Scale. Aust N Z J Psychiatry. 2012 Dec; 46(12):1165-72. PMID: 22990434.
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  212. Farabaugh A, Alpert J, Wisniewski SR, Otto MW, Fava M, Baer L, Perlis R, Friedman E, Nyer M, Bitran S, Balasubramani GK, Inamori A, Trivedi M, Thase ME. Cognitive therapy for anxious depression in STAR(*) D: what have we learned? J Affect Disord. 2012 Dec 15; 142(1-3):213-8. PMID: 22877961.
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  213. Yeung A, Feldman G, Pedrelli P, Hails K, Fava M, Reyes T, Mundt JC. The Quick Inventory of Depressive Symptomatology, clinician rated and self-report: a psychometric assessment in Chinese Americans with major depressive disorder. J Nerv Ment Dis. 2012 Aug; 200(8):712-5. PMID: 22850307; PMCID: PMC3762496.
  214. Hails K, Brill CD, Chang T, Yeung A, Fava M, Trinh NH. Cross-cultural aspects of depression management in primary care. Curr Psychiatry Rep. 2012 Aug; 14(4):336-44. PMID: 22580834.
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  216. Cusin C, Hilton GQ, Nierenberg AA, Fava M. Long-term maintenance with intramuscular ketamine for treatment-resistant bipolar II depression. Am J Psychiatry. 2012 Aug; 169(8):868-9. PMID: 22854933.
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  217. Yeung AS, Jing Y, Brenneman SK, Chang TE, Baer L, Hebden T, Kalsekar I, McQuade RD, Kurlander J, Siebenaler J, Fava M. Clinical Outcomes in Measurement-based Treatment (Comet): a trial of depression monitoring and feedback to primary care physicians. Depress Anxiety. 2012 Oct; 29(10):865-73. PMID: 22807244.
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  218. Krystal AD, McCall WV, Fava M, Joffe H, Soares CN, Huang H, Grinell T, Zummo J, Spalding W, Marshall R. Eszopiclone treatment for insomnia: effect size comparisons in patients with primary insomnia and insomnia with medical and psychiatric comorbidity. Prim Care Companion CNS Disord. 2012; 14(4). PMID: 23251857; PMCID: PMC3505126.
  219. Sanchez-Villegas A, Field AE, O'Reilly EJ, Fava M, Gortmaker S, Kawachi I, Ascherio A. Perceived and actual obesity in childhood and adolescence and risk of adult depression. J Epidemiol Community Health. 2013 Jan; 67(1):81-6. PMID: 22766776.
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  220. Soskin DP, Carl JR, Alpert J, Fava M. Antidepressant effects on emotional temperament: toward a biobehavioral research paradigm for major depressive disorder. CNS Neurosci Ther. 2012 Jun; 18(6):441-51. PMID: 22672296.
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  221. Mischoulon D, Lamon-Fava S, Selhub J, Katz J, Papakostas GI, Iosifescu DV, Yeung AS, Dording CM, Farabaugh AH, Clain AJ, Baer L, Alpert JE, Nierenberg AA, Fava M. Prevalence of MTHFR C677T and MS A2756G polymorphisms in major depressive disorder, and their impact on response to fluoxetine treatment. CNS Spectr. 2012 Jun; 17(2):76-86. PMID: 22789065; PMCID: PMC4117348.
  222. Sung SC, Haley CL, Wisniewski SR, Fava M, Nierenberg AA, Warden D, Morris DW, Kurian BT, Trivedi MH, Rush AJ. The impact of chronic depression on acute and long-term outcomes in a randomized trial comparing selective serotonin reuptake inhibitor monotherapy versus each of 2 different antidepressant medication combinations. J Clin Psychiatry. 2012 Jul; 73(7):967-76. PMID: 22687487.
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  223. Gilman SE, Trinh NH, Smoller JW, Fava M, Murphy JM, Breslau J. Psychosocial stressors and the prognosis of major depression: a test of Axis IV. Psychol Med. 2013 Feb; 43(2):303-16. PMID: 22640506; PMCID: PMC3721739.
  224. Farabaugh A, Bitran S, Nyer M, Holt DJ, Pedrelli P, Shyu I, Hollon SD, Zisook S, Baer L, Busse W, Petersen TJ, Pender M, Tucker DD, Fava M. Depression and suicidal ideation in college students. Psychopathology. 2012; 45(4):228-34. PMID: 22627683.
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  225. Mischoulon D, Alpert JE, Arning E, Bottiglieri T, Fava M, Papakostas GI. Bioavailability of S-adenosyl methionine and impact on response in a randomized, double-blind, placebo-controlled trial in major depressive disorder. J Clin Psychiatry. 2012 Jun; 73(6):843-8. PMID: 22687580; PMCID: PMC4156851.
  226. Mischoulon D, Brill CD, Ameral VE, Fava M, Yeung AS. A pilot study of acupuncture monotherapy in patients with major depressive disorder. J Affect Disord. 2012 Dec 10; 141(2-3):469-73. PMID: 22521855.
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  227. Ripke S, Wray NR, Lewis CM, Hamilton SP, Weissman MM, Breen G, Byrne EM, Blackwood DH, Boomsma DI, Cichon S, Heath AC, Holsboer F, Lucae S, Madden PA, Martin NG, McGuffin P, Muglia P, Noethen MM, Penninx BP, Pergadia ML, Potash JB, Rietschel M, Lin D, Müller-Myhsok B, Shi J, Steinberg S, Grabe HJ, Lichtenstein P, Magnusson P, Perlis RH, Preisig M, Smoller JW, Stefansson K, Uher R, Kutalik Z, Tansey KE, Teumer A, Viktorin A, Barnes MR, Bettecken T, Binder EB, Breuer R, Castro VM, Churchill SE, Coryell WH, Craddock N, Craig IW, Czamara D, De Geus EJ, Degenhardt F, Farmer AE, Fava M, Frank J, Gainer VS, Gallagher PJ, Gordon SD, Goryachev S, Gross M, Guipponi M, Henders AK, Herms S, Hickie IB, Hoefels S, Hoogendijk W, Hottenga JJ, Iosifescu DV, Ising M, Jones I, Jones L, Jung-Ying T, Knowles JA, Kohane IS, Kohli MA, Korszun A, Landen M, Lawson WB, Lewis G, Macintyre D, Maier W, Mattheisen M, McGrath PJ, McIntosh A, McLean A, Middeldorp CM, Middleton L, Montgomery GM, Murphy SN, Nauck M, Nolen WA, Nyholt DR, O'Donovan M, Oskarsson H, Pedersen N, Scheftner WA, Schulz A, Schulze TG, Shyn SI, Sigurdsson E, Slager SL, Smit JH, Stefansson H, Steffens M, Thorgeirsson T, Tozzi F, Treutlein J, Uhr M, van den Oord EJ, Van Grootheest G, Völzke H, Weilburg JB, Willemsen G, Zitman FG, Neale B, Daly M, Levinson DF, Sullivan PF. A mega-analysis of genome-wide association studies for major depressive disorder. Mol Psychiatry. 2013 Apr; 18(4):497-511. PMID: 22472876; PMCID: PMC3837431.
  228. Castro VM, Gallagher PJ, Clements CC, Murphy SN, Gainer VS, Fava M, Weilburg JB, Churchill SE, Kohane IS, Iosifescu DV, Smoller JW, Perlis RH. Incident user cohort study of risk for gastrointestinal bleed and stroke in individuals with major depressive disorder treated with antidepressants. BMJ Open. 2012; 2(2):e000544. PMID: 22466034; PMCID: PMC3330255.
  229. Perlis RH, Cusin C, Fava M. Proposed DSM-5 mixed features are associated with greater likelihood of remission in out-patients with major depressive disorder. Psychol Med. 2014 May; 44(7):1361-7. PMID: 22417535.
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  230. Davis LL, Pilkinton P, Wisniewski SR, Trivedi MH, Gaynes BN, Howland RH, Zisook S, Balasubramani GK, Fava M, Rush AJ. Effect of concurrent substance use disorder on the effectiveness of single and combination antidepressant medications for the treatment of major depression: an exploratory analysis of a single-blind randomized trial. Depress Anxiety. 2012 Feb; 29(2):111-22. PMID: 22495941; PMCID: PMC3325509.
  231. Dording CM, Dalton ED, Pencina MJ, Fava M, Mischoulon D. Comparison of academic and nonacademic sites in multi-center clinical trials. J Clin Psychopharmacol. 2012 Feb; 32(1):65-8. PMID: 22198440.
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  232. Fava M, Mischoulon D, Iosifescu D, Witte J, Pencina M, Flynn M, Harper L, Levy M, Rickels K, Pollack M. A double-blind, placebo-controlled study of aripiprazole adjunctive to antidepressant therapy among depressed outpatients with inadequate response to prior antidepressant therapy (ADAPT-A Study). Psychother Psychosom. 2012; 81(2):87-97. PMID: 22286203.
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  233. Chang TE, Jing Y, Yeung AS, Brenneman SK, Kalsekar I, Hebden T, McQuade R, Baer L, Kurlander JL, Watkins AK, Siebenaler JA, Fava M. Effect of communicating depression severity on physician prescribing patterns: findings from the Clinical Outcomes in MEasurement-based Treatment (COMET) trial. Gen Hosp Psychiatry. 2012 Mar-Apr; 34(2):105-12. PMID: 22264654.
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  234. Targum SD, Hassman H, Pinho M, Fava M. Development of a clinical global impression scale for fatigue. J Psychiatr Res. 2012 Mar; 46(3):370-4. PMID: 22236834.
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  235. Trinh NH, Larocca R, Regan S, Chang TE, Gilman SE, Fava M, Yeung A. Using the Electronic Medical Record to Examine Racial and Ethnic Differences in Depression Diagnosis and Treatment in a Primary Care Population. Prim Health Care. 2012 Jan 04; 1:1000106. PMID: 24524015.
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  236. Cassano P, Fava M, Mischoulon D. Major depressive disorder with psychosis-like symptoms among Latinos. Psychiatr Serv. 2012; 63(5):482-7. PMID: 22422016.
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  237. Gollan JK, Fava M, Kurian B, Wisniewski SR, Rush AJ, Daly E, Miyahara S, Trivedi MH. What are the clinical implications of new onset or worsening anxiety during the first two weeks of SSRI treatment for depression? Depress Anxiety. 2012 Feb; 29(2):94-101. PMID: 22147631.
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  238. Chan HN, Rush AJ, Nierenberg AA, Trivedi M, Wisniewski SR, Balasubramani GK, Friedman ES, Gaynes BN, Davis L, Morris D, Fava M. Correlates and outcomes of depressed out-patients with greater and fewer anxious symptoms: a CO-MED report. Int J Neuropsychopharmacol. 2012 Nov; 15(10):1387-99. PMID: 22129562.
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  239. Yeung A, Trinh NH, Chang TE, Fava M. The Engagement Interview Protocol (EIP): improving the acceptance of mental health treatment among Chinese immigrants. Int J Cult Ment Health. 2011 Dec 01; 4(2):91-105. PMID: 25076983.
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  240. Bech P, Fava M, Trivedi MH, Wisniewski SR, Rush AJ. Outcomes on the pharmacopsychometric triangle in bupropion-SR vs. buspirone augmentation of citalopram in the STAR*D trial. Acta Psychiatr Scand. 2012 Apr; 125(4):342-8. PMID: 22077211.
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  241. McClintock SM, Husain MM, Bernstein IH, Wisniewski SR, Trivedi MH, Morris D, Alpert J, Warden D, Luther JF, Kornstein SG, Biggs MM, Fava M, Rush AJ. Assessing anxious features in depressed outpatients. Int J Methods Psychiatr Res. 2011 Dec; 20(4):e69-82. PMID: 22057975; PMCID: PMC3708141.
  242. Trinh NH, Bedoya CA, Chang TE, Flaherty K, Fava M, Yeung A. A study of a culturally focused psychiatric consultation service for Asian American and Latino American primary care patients with depression. BMC Psychiatry. 2011 Oct 13; 11:166. PMID: 21995514; PMCID: PMC3209439.
  243. Chen JA, Papakostas GI, Youn SJ, Baer L, Clain AJ, Fava M, Mischoulon D. Association between patient beliefs regarding assigned treatment and clinical response: reanalysis of data from the Hypericum Depression Trial Study Group. J Clin Psychiatry. 2011 Dec; 72(12):1669-76. PMID: 22053942.
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  244. Zisook S, Lesser IM, Lebowitz B, Rush AJ, Kallenberg G, Wisniewski SR, Nierenberg AA, Fava M, Luther JF, Morris DW, Trivedi MH. Effect of antidepressant medication treatment on suicidal ideation and behavior in a randomized trial: an exploratory report from the Combining Medications to Enhance Depression Outcomes Study. J Clin Psychiatry. 2011 Oct; 72(10):1322-32. PMID: 22075098.
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  245. Denninger JW, van Nieuwenhuizen AO, Wisniewski SR, Luther JF, Trivedi MH, Rush AJ, Gollan JK, Pizzagalli DA, Fava M. Changes in depressive symptoms and social functioning in the sequenced treatment alternatives to relieve depression study. J Nerv Ment Dis. 2011 Oct; 199(10):807-10. PMID: 21964277.
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  246. Targum SD, Fava M. Fatigue as a residual symptom of depression. Innov Clin Neurosci. 2011 Oct; 8(10):40-3. PMID: 22132370; PMCID: PMC3225130.
  247. Evins AE, Pachas G, Mischoulon D, Urbanoski K, Carlini S, Sousa J, Bentley K, Rigotti NA, Nino-Gomez J, Loebl T, Janes AC, Kaufman MJ, Fava M. A double-blind, placebo-controlled trial of the NMDA glycine site antagonist, GW468816, for prevention of relapse to smoking in females. J Clin Psychopharmacol. 2011 Oct; 31(5):597-602. PMID: 21869693; PMCID: PMC3741043.
  248. Lesser IM, Zisook S, Gaynes BN, Wisniewski SR, Luther JF, Fava M, Khan A, McGrath P, Warden D, Rush AJ, Trivedi M. Effects of race and ethnicity on depression treatment outcomes: the CO-MED trial. Psychiatr Serv. 2011 Oct; 62(10):1167-79. PMID: 21969643.
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  249. Yeung A, Hails K, Chang T, Trinh NH, Fava M. A study of the effectiveness of telepsychiatry-based culturally sensitive collaborative treatment of depressed Chinese Americans. BMC Psychiatry. 2011 Sep 26; 11:154. PMID: 21943315; PMCID: PMC3190334.
  250. Mischoulon D, Witte J, Levy M, Papakostas GI, Pet LR, Hsieh WH, Pencina MJ, Ward S, Pollack MH, Fava M. Efficacy of dose increase among nonresponders to low-dose aripiprazole augmentation in patients with inadequate response to antidepressant treatment: a randomized, double-blind, placebo-controlled, efficacy trial. J Clin Psychiatry. 2012 Mar; 73(3):353-7. PMID: 21939613.
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  251. Tran P, Skolnick P, Czobor P, Huang NY, Bradshaw M, McKinney A, Fava M. Efficacy and tolerability of the novel triple reuptake inhibitor amitifadine in the treatment of patients with major depressive disorder: a randomized, double-blind, placebo-controlled trial. J Psychiatr Res. 2012 Jan; 46(1):64-71. PMID: 21925682.
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  252. Friedman ES, Davis LL, Zisook S, Wisniewski SR, Trivedi MH, Fava M, Rush AJ. Baseline depression severity as a predictor of single and combination antidepressant treatment outcome: results from the CO-MED trial. Eur Neuropsychopharmacol. 2012 Mar; 22(3):183-99. PMID: 21920711; PMCID: PMC3273676.
  253. Gilman SE, Breslau J, Trinh NH, Fava M, Murphy JM, Smoller JW. Bereavement and the diagnosis of major depressive episode in the National Epidemiologic Survey on Alcohol and Related Conditions. J Clin Psychiatry. 2012 Feb; 73(2):208-15. PMID: 21903020; PMCID: PMC3721753.
  254. Fava M, Shelton RC, Zajecka JM. Evidence for the use of l-methylfolate combined with antidepressants in MDD. J Clin Psychiatry. 2011 Aug; 72(8):e25. PMID: 21899813.
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  255. Farabaugh AH, Locascio JJ, Yap L, Fava M, Bitran S, Sousa JL, Growdon JH. Assessing depression and factors possibly associated with depression during the course of Parkinson's disease. Ann Clin Psychiatry. 2011 Aug; 23(3):171-7. PMID: 21808748; PMCID: PMC3164778.
  256. Desseilles M, Witte J, Chang TE, Iovieno N, Dording CM, Ashih H, Nyer M, Freeman MP, Fava M, Mischoulon D. Assessing the adequacy of past antidepressant trials: a clinician's guide to the antidepressant treatment response questionnaire. J Clin Psychiatry. 2011 Aug; 72(8):1152-4. PMID: 21899818.
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  257. Janes AC, Smoller JW, David SP, Frederick BD, Haddad S, Basu A, Fava M, Evins AE, Kaufman MJ. Association between CHRNA5 genetic variation at rs16969968 and brain reactivity to smoking images in nicotine dependent women. Drug Alcohol Depend. 2012 Jan 01; 120(1-3):7-13. PMID: 21764527; PMCID: PMC3203995.
  258. Bitran S, Farabaugh AH, Ameral VE, LaRocca RA, Clain AJ, Fava M, Mischoulon D. Do early changes in the HAM-D-17 anxiety/somatization factor items affect the treatment outcome among depressed outpatients? Comparison of two controlled trials of St John's wort (Hypericum perforatum) versus a SSRI. Int Clin Psychopharmacol. 2011 Jul; 26(4):206-12. PMID: 21278577; PMCID: PMC3111899.
  259. Perlis RH, Iosifescu DV, Castro VM, Murphy SN, Gainer VS, Minnier J, Cai T, Goryachev S, Zeng Q, Gallagher PJ, Fava M, Weilburg JB, Churchill SE, Kohane IS, Smoller JW. Using electronic medical records to enable large-scale studies in psychiatry: treatment resistant depression as a model. Psychol Med. 2012 Jan; 42(1):41-50. PMID: 21682950; PMCID: PMC3837420.
  260. Trivedi MH, Wisniewski SR, Morris DW, Fava M, Gollan JK, Warden D, Nierenberg AA, Gaynes BN, Husain MM, Luther JF, Zisook S, Rush AJ. Concise Health Risk Tracking scale: a brief self-report and clinician rating of suicidal risk. J Clin Psychiatry. 2011 Jun; 72(6):757-64. PMID: 21733476.
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  261. Trivedi MH, Wisniewski SR, Morris DW, Fava M, Kurian BT, Gollan JK, Nierenberg AA, Warden D, Gaynes BN, Luther JF, Rush AJ. Concise Associated Symptoms Tracking scale: a brief self-report and clinician rating of symptoms associated with suicidality. J Clin Psychiatry. 2011 Jun; 72(6):765-74. PMID: 21733477.
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  262. Sung SC, Dryman MT, Marks E, Shear MK, Ghesquiere A, Fava M, Simon NM. Complicated grief among individuals with major depression: prevalence, comorbidity, and associated features. J Affect Disord. 2011 Nov; 134(1-3):453-8. PMID: 21621849; PMCID: PMC3170428.
  263. Posternak MA, Baer L, Nierenberg AA, Fava M. Response rates to fluoxetine in subjects who initially show no improvement. J Clin Psychiatry. 2011 Jul; 72(7):949-54. PMID: 21672502.
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  264. Bobo WV, Chen H, Trivedi MH, Stewart JW, Nierenberg AA, Fava M, Kurian BT, Warden D, Morris DW, Luther JF, Husain MM, Cook IA, Lesser IM, Kornstein SG, Wisniewski SR, Rush AJ, Shelton RC. Randomized comparison of selective serotonin reuptake inhibitor (escitalopram) monotherapy and antidepressant combination pharmacotherapy for major depressive disorder with melancholic features: a CO-MED report. J Affect Disord. 2011 Oct; 133(3):467-76. PMID: 21601287.
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  265. Mashhoon Y, Janes AC, Jensen JE, Prescot AP, Pachas G, Renshaw PF, Fava M, Evins AE, Kaufman MJ. Anterior cingulate proton spectroscopy glutamate levels differ as a function of smoking cessation outcome. Prog Neuropsychopharmacol Biol Psychiatry. 2011 Aug 15; 35(7):1709-13. PMID: 21616118; PMCID: PMC3303218.
  266. Rush AJ, Trivedi MH, Stewart JW, Nierenberg AA, Fava M, Kurian BT, Warden D, Morris DW, Luther JF, Husain MM, Cook IA, Shelton RC, Lesser IM, Kornstein SG, Wisniewski SR. Combining medications to enhance depression outcomes (CO-MED): acute and long-term outcomes of a single-blind randomized study. Am J Psychiatry. 2011 Jul; 168(7):689-701. PMID: 21536692.
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  267. Trinh NH, Youn SJ, Sousa J, Regan S, Bedoya CA, Chang TE, Fava M, Yeung A. Using electronic medical records to determine the diagnosis of clinical depression. Int J Med Inform. 2011 Jul; 80(7):533-40. PMID: 21514880; PMCID: PMC3124810.
  268. Wickramaratne P, Gameroff MJ, Pilowsky DJ, Hughes CW, Garber J, Malloy E, King C, Cerda G, Sood AB, Alpert JE, Trivedi MH, Fava M, Rush AJ, Wisniewski S, Weissman MM. Children of depressed mothers 1 year after remission of maternal depression: findings from the STAR*D-Child study. Am J Psychiatry. 2011 Jun; 168(6):593-602. PMID: 21406462; PMCID: PMC3423977.
  269. Daly EJ, Trivedi MH, Fava M, Shelton R, Wisniewski SR, Morris DW, Stegman D, Preskorn SH, Rush AJ. The relationship between adverse events during selective serotonin reuptake inhibitor treatment for major depressive disorder and nonremission in the suicide assessment methodology study. J Clin Psychopharmacol. 2011 Feb; 31(1):31-8. PMID: 21192140.
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  270. Fava M, Dording CM, Baker RA, Mankoski R, Tran QV, Forbes RA, Eudicone JM, Owen R, Berman RM. Effects of adjunctive aripiprazole on sexual functioning in patients with major depressive disorder and an inadequate response to standard antidepressant monotherapy: a post hoc analysis of 3 randomized, double-blind, placebo-controlled studies. Prim Care Companion CNS Disord. 2011; 13(1). PMID: 21731833; PMCID: PMC3121211.
  271. Fava M, Asnis GM, Shrivastava RK, Lydiard B, Bastani B, Sheehan DV, Roth T. Improved insomnia symptoms and sleep-related next-day functioning in patients with comorbid major depressive disorder and insomnia following concomitant zolpidem extended-release 12.5 mg and escitalopram treatment: a randomized controlled trial. J Clin Psychiatry. 2011 Jul; 72(7):914-28. PMID: 21208597.
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  272. Perlis RH, Uher R, Ostacher M, Goldberg JF, Trivedi MH, Rush AJ, Fava M. Association between bipolar spectrum features and treatment outcomes in outpatients with major depressive disorder. Arch Gen Psychiatry. 2011 Apr; 68(4):351-60. PMID: 21135313; PMCID: PMC3794668.
  273. Murphy JM, Gilman SE, Lesage A, Horton NJ, Rasic D, Trinh NH, Alamiri B, Sobol AM, Fava M, Smoller JW. Time trends in mortality associated with depression: findings from the Stirling County study. Can J Psychiatry. 2010 Dec; 55(12):776-83. PMID: 21172098; PMCID: PMC3462356.
  274. Blood AJ, Iosifescu DV, Makris N, Perlis RH, Kennedy DN, Dougherty DD, Kim BW, Lee MJ, Wu S, Lee S, Calhoun J, Hodge SM, Fava M, Rosen BR, Smoller JW, Gasic GP, Breiter HC. Microstructural abnormalities in subcortical reward circuitry of subjects with major depressive disorder. PLoS One. 2010 Nov 29; 5(11):e13945. PMID: 21124764; PMCID: PMC2993928.
  275. Pedrelli P, Bitran S, Shyu I, Baer L, Guidi J, Tucker DD, Vitali M, Fava M, Zisook S, Farabaugh AH. Compulsive alcohol use and other high-risk behaviors among college students. Am J Addict. 2011 Jan-Feb; 20(1):14-20. PMID: 21175916.
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  276. Tedeschini E, Fava M, Papakostas GI. Placebo-controlled, antidepressant clinical trials cannot be shortened to less than 4 weeks' duration: a pooled analysis of randomized clinical trials employing a diagnostic odds ratio-based approach. J Clin Psychiatry. 2011 Jan; 72(1):98-113. PMID: 21208576.
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  277. Fava M, Schaefer K, Huang H, Wilson A, Iosifescu DV, Mischoulon D, Wessel TC. A post hoc analysis of the effect of nightly administration of eszopiclone and a selective serotonin reuptake inhibitor in patients with insomnia and anxious depression. J Clin Psychiatry. 2011 Apr; 72(4):473-9. PMID: 21208574.
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  278. Perlis RH, Huang J, Purcell S, Fava M, Rush AJ, Sullivan PF, Hamilton SP, McMahon FJ, Schulze TG, Schulze T, Potash JB, Zandi PP, Willour VL, Penninx BW, Boomsma DI, Vogelzangs N, Middeldorp CM, Rietschel M, Nöthen M, Cichon S, Gurling H, Bass N, McQuillin A, Hamshere M, Craddock N, Sklar P, Smoller JW. Genome-wide association study of suicide attempts in mood disorder patients. Am J Psychiatry. 2010 Dec; 167(12):1499-507. PMID: 21041247; PMCID: PMC3795390.
  279. Fava M, Mischoulon D. Evidence for folate in combination with antidepressants at initiation of therapy. J Clin Psychiatry. 2010 Nov; 71(11):e31. PMID: 21114944.
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  280. Pedrelli P, Farabaugh AH, Zisook S, Tucker D, Rooney K, Katz J, Clain AJ, Petersen TJ, Fava M. Gender, depressive symptoms and patterns of alcohol use among college students. Psychopathology. 2011; 44(1):27-33. PMID: 20980785.
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  281. Yeung A, Shyu I, Fisher L, Wu S, Yang H, Fava M. Culturally sensitive collaborative treatment for depressed chinese americans in primary care. Am J Public Health. 2010 Dec; 100(12):2397-402. PMID: 20966373; PMCID: PMC2978195.
  282. Chandler GM, Iosifescu DV, Pollack MH, Targum SD, Fava M. RESEARCH: Validation of the Massachusetts General Hospital Antidepressant Treatment History Questionnaire (ATRQ). CNS Neurosci Ther. 2010 Oct; 16(5):322-5. PMID: 19769599.
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  283. Fava M. Using complementary and alternative medicines for depression. J Clin Psychiatry. 2010 Sep; 71(9):e24. PMID: 20923617.
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  284. Huang J, Perlis RH, Lee PH, Rush AJ, Fava M, Sachs GS, Lieberman J, Hamilton SP, Sullivan P, Sklar P, Purcell S, Smoller JW. Cross-disorder genomewide analysis of schizophrenia, bipolar disorder, and depression. Am J Psychiatry. 2010 Oct; 167(10):1254-63. PMID: 20713499.
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  285. Janes AC, Pizzagalli DA, Richardt S, Frederick Bde B, Holmes AJ, Sousa J, Fava M, Evins AE, Kaufman MJ. Neural substrates of attentional bias for smoking-related cues: an FMRI study. Neuropsychopharmacology. 2010 Nov; 35(12):2339-45. PMID: 20703221; PMCID: PMC2955848.
  286. Yeung AS, Ameral VE, Chuzi SE, Fava M, Mischoulon D. A pilot study of acupuncture augmentation therapy in antidepressant partial and non-responders with major depressive disorder. J Affect Disord. 2011 Apr; 130(1-2):285-9. PMID: 20692042.
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  287. Chang T, Fava M. The future of psychopharmacology of depression. J Clin Psychiatry. 2010 Aug; 71(8):971-5. PMID: 20797377.
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  288. Farabaugh A, Sonawalla S, Johnson DP, Witte J, Papakostas GI, Goodness T, Clain A, Baer L, Mischoulon D, Fava M, Harley R. Early improvements in anxiety, depression, and anger/hostility symptoms and response to antidepressant treatment. Ann Clin Psychiatry. 2010 Aug; 22(3):166-71. PMID: 20680189.
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  289. Dording CM, Mischoulon D, Goodness TM, Baer L, Clain A, Stewart JW, Matthews JD, McGrath PJ, Nierenberg AA, Fava M, Papakostas GI. Psychoticism and paranoid ideation in patients with nonpsychotic major depressive disorder: prevalence, response to treatment, and impact on short- and long-term treatment outcome. CNS Spectr. 2010 Aug; 15(8):515-21. PMID: 20703198.
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  290. DeBattista C, Kinrys G, Hoffman D, Goldstein C, Zajecka J, Kocsis J, Teicher M, Potkin S, Preda A, Multani G, Brandt L, Schiller M, Iosifescu D, Fava M. The use of referenced-EEG (rEEG) in assisting medication selection for the treatment of depression. J Psychiatr Res. 2011 Jan; 45(1):64-75. PMID: 20598710.
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  291. Papakostas GI, Mischoulon D, Shyu I, Alpert JE, Fava M. S-adenosyl methionine (SAMe) augmentation of serotonin reuptake inhibitors for antidepressant nonresponders with major depressive disorder: a double-blind, randomized clinical trial. Am J Psychiatry. 2010 Aug; 167(8):942-8. PMID: 20595412.
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  292. Trinh NH, Shyu I, McGrath PJ, Clain A, Baer L, Fava M, Yeung A. Examining the role of race and ethnicity in relapse rates of major depressive disorder. Compr Psychiatry. 2011 Mar-Apr; 52(2):151-5. PMID: 21295221; PMCID: PMC3052934.
  293. Farabaugh AH, Bitran S, Witte J, Alpert J, Chuzi S, Clain AJ, Baer L, Fava M, McGrath PJ, Dording C, Mischoulon D, Papakostas GI. Anxious depression and early changes in the HAMD-17 anxiety-somatization factor items and antidepressant treatment outcome. Int Clin Psychopharmacol. 2010 Jul; 25(4):214-7. PMID: 20400905; PMCID: PMC2909033.
  294. Iovieno N, Dalton ED, Fava M, Mischoulon D. Second-tier natural antidepressants: review and critique. J Affect Disord. 2011 May; 130(3):343-57. PMID: 20579741.
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  295. Fornaro M, Iovieno N, Clementi N, Boscaro M, Paggi F, Balercia G, Fava M, Papakostas GI. Diagnosis of co-morbid axis-I psychiatric disorders among women with newly diagnosed, untreated endocrine disorders. World J Biol Psychiatry. 2010 Dec; 11(8):991-6. PMID: 20569197.
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  296. Sunderajan P, Gaynes BN, Wisniewski SR, Miyahara S, Fava M, Akingbala F, DeVeaugh-Geiss J, Rush AJ, Trivedi MH. Insomnia in patients with depression: a STAR*D report. CNS Spectr. 2010 Jun; 15(6):394-404. PMID: 20625372.
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  297. Warden D, Trivedi MH, Wisniewski SR, Kurian B, Zisook S, Kornstein SG, Friedman ES, Miyahara S, Leuchter AF, Fava M, Rush AJ. Early adverse events and attrition in selective serotonin reuptake inhibitor treatment: a suicide assessment methodology study report. J Clin Psychopharmacol. 2010 Jun; 30(3):259-66. PMID: 20473060; PMCID: PMC3119579.
  298. Freeman MP, Fava M, Lake J, Trivedi MH, Wisner KL, Mischoulon D. Complementary and alternative medicine in major depressive disorder: the American Psychiatric Association Task Force report. J Clin Psychiatry. 2010 Jun; 71(6):669-81. PMID: 20573326.
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  299. Freeman MP, Mischoulon D, Tedeschini E, Goodness T, Cohen LS, Fava M, Papakostas GI. Complementary and alternative medicine for major depressive disorder: a meta-analysis of patient characteristics, placebo-response rates, and treatment outcomes relative to standard antidepressants. J Clin Psychiatry. 2010 Jun; 71(6):682-8. PMID: 20573327.
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  300. Kim BW, Kennedy DN, Lehár J, Lee MJ, Blood AJ, Lee S, Perlis RH, Smoller JW, Morris R, Fava M, Breiter HC. Recurrent, robust and scalable patterns underlie human approach and avoidance. PLoS One. 2010 May 26; 5(5):e10613. PMID: 20532247.
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  301. Binder EB, Owens MJ, Liu W, Deveau TC, Rush AJ, Trivedi MH, Fava M, Bradley B, Ressler KJ, Nemeroff CB. Association of polymorphisms in genes regulating the corticotropin-releasing factor system with antidepressant treatment response. Arch Gen Psychiatry. 2010 Apr; 67(4):369-79. PMID: 20368512.
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  302. Perlis RH, Smoller JW, Mysore J, Sun M, Gillis T, Purcell S, Rietschel M, Nöthen MM, Witt S, Maier W, Iosifescu DV, Sullivan P, Rush AJ, Fava M, Breiter H, Macdonald M, Gusella J. Prevalence of incompletely penetrant Huntington's disease alleles among individuals with major depressive disorder. Am J Psychiatry. 2010 May; 167(5):574-9. PMID: 20360314; PMCID: PMC3114558.
  303. Stahl SM, Fava M, Trivedi MH, Caputo A, Shah A, Post A. Agomelatine in the treatment of major depressive disorder: an 8-week, multicenter, randomized, placebo-controlled trial. J Clin Psychiatry. 2010 May; 71(5):616-26. PMID: 20361916.
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  304. Fava M. The possible antianxiety and mood-stabilizing effects of rufinamide. Psychother Psychosom. 2010; 79(3):194-5. PMID: 20234151.
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  305. Tedeschini E, Fava M, Goodness TM, Papakostas GI. Relationship between probability of receiving placebo and probability of prematurely discontinuing treatment in double-blind, randomized clinical trials for MDD: a meta-analysis. Eur Neuropsychopharmacol. 2010 Aug; 20(8):562-7. PMID: 20219330.
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  306. Perlis RH, Ostacher M, Fava M, Nierenberg AA, Sachs GS, Rosenbaum JF. Assuring that double-blind is blind. Am J Psychiatry. 2010 Mar; 167(3):250-2. PMID: 20194487.
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  307. Farabaugh A, Locascio JJ, Yap L, Growdon J, Fava M, Crawford C, Matthews J, McCutchen J, Buchin J, Pava J, Alpert JE. Cognitive-behavioral therapy for patients with Parkinson's disease and comorbid major depressive disorder. Psychosomatics. 2010 Mar-Apr; 51(2):124-9. PMID: 20332287.
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  308. Papakostas GI, Charles D, Fava M. Are typical starting doses of the selective serotonin reuptake inhibitors sub-optimal? A meta-analysis of randomized, double-blind, placebo-controlled, dose-finding studies in major depressive disorder. World J Biol Psychiatry. 2010 Mar; 11(2 Pt 2):300-7. PMID: 20218793.
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  309. Yang H, Sinicropi-Yao L, Chuzi S, Youn SJ, Clain A, Baer L, Chen Y, McGrath PJ, Fava M, Papakostas GI. Residual sleep disturbance and risk of relapse during the continuation/maintenance phase treatment of major depressive disorder with the selective serotonin reuptake inhibitor fluoxetine. Ann Gen Psychiatry. 2010 Feb 26; 9:10. PMID: 20187924; PMCID: PMC2837657.
  310. Janes AC, Pizzagalli DA, Richardt S, deB Frederick B, Chuzi S, Pachas G, Culhane MA, Holmes AJ, Fava M, Evins AE, Kaufman MJ. Brain reactivity to smoking cues prior to smoking cessation predicts ability to maintain tobacco abstinence. Biol Psychiatry. 2010 Apr 15; 67(8):722-9. PMID: 20172508; PMCID: PMC2954596.
  311. Fava M. Switching treatments for complicated depression. J Clin Psychiatry. 2010 Feb; 71(2):e04. PMID: 20193643.
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  312. Casamassima F, Huang J, Fava M, Sachs GS, Smoller JW, Cassano GB, Lattanzi L, Fagerness J, Stange JP, Perlis RH. Phenotypic effects of a bipolar liability gene among individuals with major depressive disorder. Am J Med Genet B Neuropsychiatr Genet. 2010 Jan 05; 153B(1):303-9. PMID: 19388002.
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  313. Papakostas GI, Clain A, Ameral VE, Baer L, Brintz C, Smith WT, Londborg PD, Glaudin V, Painter JR, Fava M. Fluoxetine-clonazepam cotherapy for anxious depression: an exploratory, post-hoc analysis of a randomized, double blind study. Int Clin Psychopharmacol. 2010 Jan; 25(1):17-21. PMID: 19898245.
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  314. Pedrelli P, Baer L, Losifescu DV, Fava M. Relationship between residual symptoms of depression and self-reported cognitive impairment. CNS Spectr. 2010 Jan; 15(1):46-51. PMID: 20394184.
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  315. Janes AC, Frederick Bd, Richardt S, Burbridge C, Merlo-Pich E, Renshaw PF, Evins AE, Fava M, Kaufman MJ. Brain fMRI reactivity to smoking-related images before and during extended smoking abstinence. Exp Clin Psychopharmacol. 2009 Dec; 17(6):365-73. PMID: 19968401; PMCID: PMC3742373.
  316. Miller KK, Perlis RH, Papakostas GI, Mischoulon D, Losifescu DV, Brick DJ, Fava M. Low-dose transdermal testosterone augmentation therapy improves depression severity in women. CNS Spectr. 2009 Dec; 14(12):688-94. PMID: 20394176; PMCID: PMC4081446.
  317. Davis LL, Wisniewski SR, Howland RH, Trivedi MH, Husain MM, Fava M, McGrath PJ, Balasubramani GK, Warden D, Rush AJ. Does comorbid substance use disorder impair recovery from major depression with SSRI treatment? An analysis of the STAR*D level one treatment outcomes. Drug Alcohol Depend. 2010 Mar 01; 107(2-3):161-70. PMID: 19945804.
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  318. Fava M. Augmentation and combination strategies for complicated depression. J Clin Psychiatry. 2009 Nov; 70(11):e40. PMID: 20031088.
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  319. Gaynes BN, Warden D, Trivedi MH, Wisniewski SR, Fava M, Rush AJ. What did STAR*D teach us? Results from a large-scale, practical, clinical trial for patients with depression. Psychiatr Serv. 2009 Nov; 60(11):1439-45. PMID: 19880458.
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  320. Montgomery SA, Fava M, Padmanabhan SK, Guico-Pabia CJ, Tourian KA. Discontinuation symptoms and taper/poststudy-emergent adverse events with desvenlafaxine treatment for major depressive disorder. Int Clin Psychopharmacol. 2009 Nov; 24(6):296-305. PMID: 19779354.
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  321. Warden D, Trivedi MH, Wisniewski SR, Lesser IM, Mitchell J, Balasubramani GK, Fava M, Shores-Wilson K, Stegman D, Rush AJ. Identifying risk for attrition during treatment for depression. Psychother Psychosom. 2009; 78(6):372-9. PMID: 19738403; PMCID: PMC2820313.
  322. Gasic GP, Smoller JW, Perlis RH, Sun M, Lee S, Kim BW, Lee MJ, Holt DJ, Blood AJ, Makris N, Kennedy DK, Hoge RD, Calhoun J, Fava M, Gusella JF, Breiter HC. BDNF, relative preference, and reward circuitry responses to emotional communication. Am J Med Genet B Neuropsychiatr Genet. 2009 Sep 05; 150B(6):762-81. PMID: 19388013.
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  323. Kashner TM, Trivedi MH, Wicker A, Fava M, Shores-Wilson K, Wisniewski SR, Rush AJ. Release bias in accessing medical records in clinical trials: a STAR*D report. Int J Methods Psychiatr Res. 2009 Sep; 18(3):147-58. PMID: 19701922.
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  324. Farabaugh AH, Locascio JJ, Yap L, Weintraub D, McDonald WM, Agoston M, Alpert JE, Growdon J, Fava M. Pattern of depressive symptoms in Parkinson's disease. Psychosomatics. 2009 Sep-Oct; 50(5):448-54. PMID: 19855029; PMCID: PMC3529169.
  325. Bryan C, Songer T, Brooks MM, Rush AJ, Thase ME, Gaynes B, Balasubramani GK, Trivedi MH, Fava M, Wisniewski SR. The impact of diabetes on depression treatment outcomes. Gen Hosp Psychiatry. 2010 Jan-Feb; 32(1):33-41. PMID: 20114126.
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  326. Leuchter AF, Cook IA, Marangell LB, Gilmer WS, Burgoyne KS, Howland RH, Trivedi MH, Zisook S, Jain R, McCracken JT, Fava M, Iosifescu D, Greenwald S. Comparative effectiveness of biomarkers and clinical indicators for predicting outcomes of SSRI treatment in Major Depressive Disorder: results of the BRITE-MD study. Psychiatry Res. 2009 Sep 30; 169(2):124-31. PMID: 19712979.
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  327. Kashner TM, Trivedi MH, Wicker A, Fava M, Wisniewski SR, Rush AJ. The impact of nonclinical factors on care use for patients with depression: a STAR*D report. CNS Neurosci Ther. 2009; 15(4):320-32. PMID: 19712127.
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  328. Leuchter AF, Cook IA, Gilmer WS, Marangell LB, Burgoyne KS, Howland RH, Trivedi MH, Zisook S, Jain R, Fava M, Iosifescu D, Greenwald S. Effectiveness of a quantitative electroencephalographic biomarker for predicting differential response or remission with escitalopram and bupropion in major depressive disorder. Psychiatry Res. 2009 Sep 30; 169(2):132-8. PMID: 19709754.
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  329. Mischoulon D, Papakostas GI, Dording CM, Farabaugh AH, Sonawalla SB, Agoston AM, Smith J, Beaumont EC, Dahan LE, Alpert JE, Nierenberg AA, Fava M. A double-blind, randomized controlled trial of ethyl-eicosapentaenoate for major depressive disorder. J Clin Psychiatry. 2009 Dec; 70(12):1636-44. PMID: 19709502; PMCID: PMC2918427.
  330. Rush AJ, Warden D, Wisniewski SR, Fava M, Trivedi MH, Gaynes BN, Nierenberg AA. STAR*D: revising conventional wisdom. CNS Drugs. 2009 Aug; 23(8):627-47. PMID: 19594193.
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  331. Fava M, Wisniewski SR, Thase ME, Baker RA, Tran QV, Pikalov A, Yang H, Marcus RN, Berman RM. Metabolic assessment of aripiprazole as adjunctive therapy in major depressive disorder: a pooled analysis of 2 studies. J Clin Psychopharmacol. 2009 Aug; 29(4):362-7. PMID: 19593176.
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  332. Papakostas GI, Chuzi SE, Sousa JL, Fava M. 5HT1A-mediated stimulation of cortisol release in major depression: use of non-invasive cortisol measurements to predict clinical response. Eur Arch Psychiatry Clin Neurosci. 2010 Mar; 260(2):175-80. PMID: 19641981.
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  333. Yang H, Chuzi S, Sinicropi-Yao L, Johnson D, Chen Y, Clain A, Baer L, McGrath PJ, Stewart JW, Fava M, Papakostas GI. Type of residual symptom and risk of relapse during the continuation/maintenance phase treatment of major depressive disorder with the selective serotonin reuptake inhibitor fluoxetine. Eur Arch Psychiatry Clin Neurosci. 2010 Mar; 260(2):145-50. PMID: 19572158.
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  334. Iosifescu DV, Greenwald S, Devlin P, Mischoulon D, Denninger JW, Alpert JE, Fava M. Frontal EEG predictors of treatment outcome in major depressive disorder. Eur Neuropsychopharmacol. 2009 Nov; 19(11):772-7. PMID: 19574030.
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  335. Fava M. Partial responders to antidepressant treatment: switching strategies. J Clin Psychiatry. 2009 Jul; 70(7):e24. PMID: 19653970.
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  336. Kaufman MJ, Prescot AP, Ongur D, Evins AE, Barros TL, Medeiros CL, Covell J, Wang L, Fava M, Renshaw PF. Oral glycine administration increases brain glycine/creatine ratios in men: a proton magnetic resonance spectroscopy study. Psychiatry Res. 2009 Aug 30; 173(2):143-9. PMID: 19556112; PMCID: PMC2713375.
  337. Fava M, Asnis GM, Shrivastava R, Lydiard B, Bastani B, Sheehan D, Roth T. Zolpidem extended-release improves sleep and next-day symptoms in comorbid insomnia and generalized anxiety disorder. J Clin Psychopharmacol. 2009 Jun; 29(3):222-30. PMID: 19440075.
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  338. Nierenberg AA, Husain MM, Trivedi MH, Fava M, Warden D, Wisniewski SR, Miyahara S, Rush AJ. Residual symptoms after remission of major depressive disorder with citalopram and risk of relapse: a STAR*D report. Psychol Med. 2010 Jan; 40(1):41-50. PMID: 19460188.
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  339. Yeung A, Johnson DP, Trinh NH, Weng WC, Kvedar J, Fava M. Feasibility and effectiveness of telepsychiatry services for chinese immigrants in a nursing home. Telemed J E Health. 2009 May; 15(4):336-41. PMID: 19441951.
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  340. Pizzagalli DA, Holmes AJ, Dillon DG, Goetz EL, Birk JL, Bogdan R, Dougherty DD, Iosifescu DV, Rauch SL, Fava M. Reduced caudate and nucleus accumbens response to rewards in unmedicated individuals with major depressive disorder. Am J Psychiatry. 2009 Jun; 166(6):702-10. PMID: 19411368; PMCID: PMC2735451.
  341. Stewart JW, McGrath PJ, Fava M, Wisniewski SR, Zisook S, Cook I, Nierenberg AA, Trivedi MH, Balasubramani GK, Warden D, Lesser I, John Rush A. Do atypical features affect outcome in depressed outpatients treated with citalopram? Int J Neuropsychopharmacol. 2010 Feb; 13(1):15-30. PMID: 19341509.
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  342. Berman RM, Fava M, Thase ME, Trivedi MH, Swanink R, McQuade RD, Carson WH, Adson D, Taylor L, Hazel J, Marcus RN. Aripiprazole augmentation in major depressive disorder: a double-blind, placebo-controlled study in patients with inadequate response to antidepressants. CNS Spectr. 2009 Apr; 14(4):197-206. PMID: 19407731.
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  343. Weiss AP, Guidi J, Fava M. Closing the efficacy-effectiveness gap: translating both the what and the how from randomized controlled trials to clinical practice. J Clin Psychiatry. 2009 Apr; 70(4):446-9. PMID: 19403096.
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  344. Wisniewski SR, Rush AJ, Nierenberg AA, Gaynes BN, Warden D, Luther JF, McGrath PJ, Lavori PW, Thase ME, Fava M, Trivedi MH. Can phase III trial results of antidepressant medications be generalized to clinical practice? A STAR*D report. Am J Psychiatry. 2009 May; 166(5):599-607. PMID: 19339358.
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  345. Perlis RH, Laje G, Smoller JW, Fava M, Rush AJ, McMahon FJ. Genetic and clinical predictors of sexual dysfunction in citalopram-treated depressed patients. Neuropsychopharmacology. 2009 Jun; 34(7):1819-28. PMID: 19295509.
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  346. Fava M, Hwang I, Rush AJ, Sampson N, Walters EE, Kessler RC. The importance of irritability as a symptom of major depressive disorder: results from the National Comorbidity Survey Replication. Mol Psychiatry. 2010 Aug; 15(8):856-67. PMID: 19274052.
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  347. Kashner TM, Trivedi MH, Wicker A, Fava M, Greist JH, Mundt JC, Shores-Wilson K, Rush AJ, Wisniewski SR. Voice response system to measure healthcare costs: a STAR*D report. Am J Manag Care. 2009 Mar; 15(3):153-62. PMID: 19298096.
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  348. Zisook S, Trivedi MH, Warden D, Lebowitz B, Thase ME, Stewart JW, Moutier C, Fava M, Wisniewski SR, Luther J, Rush AJ. Clinical correlates of the worsening or emergence of suicidal ideation during SSRI treatment of depression: an examination of citalopram in the STAR*D study. J Affect Disord. 2009 Sep; 117(1-2):63-73. PMID: 19217668.
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  349. Fava M, Iosifescu DV, Pedrelli P, Baer L. Reliability and validity of the Massachusetts general hospital cognitive and physical functioning questionnaire. Psychother Psychosom. 2009; 78(2):91-7. PMID: 19218827.
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  350. Perlis RH, Fava M, Trivedi MH, Alpert J, Luther JF, Wisniewski SR, Rush AJ. Irritability is associated with anxiety and greater severity, but not bipolar spectrum features, in major depressive disorder. Acta Psychiatr Scand. 2009 Apr; 119(4):282-9. PMID: 19207123; PMCID: PMC3312008.
  351. Matthews JD, Siefert C, Dording C, Denninger JW, Park L, van Nieuwenhuizen AO, Sklarsky K, Hilliker S, Homberger C, Rooney K, Fava M. An open study of aripiprazole and escitalopram for psychotic major depressive disorder. J Clin Psychopharmacol. 2009 Feb; 29(1):73-6. PMID: 19142112.
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  352. Feldman G, Harley R, Kerrigan M, Jacobo M, Fava M. Change in emotional processing during a dialectical behavior therapy-based skills group for major depressive disorder. Behav Res Ther. 2009 Apr; 47(4):316-21. PMID: 19232571.
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  353. Nelson JC, Thase ME, Trivedi MH, Fava M, Han J, Van Tran Q, Pikalov A, Qi Y, Carlson BX, Marcus RN, Berman RM. Safety and Tolerability of Adjunctive Aripiprazole in Major Depressive Disorder: A Pooled Post Hoc Analysis (studies CN138-139 and CN138-163). Prim Care Companion J Clin Psychiatry. 2009; 11(6):344-52. PMID: 20098527.
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  354. Papakostas GI, Cooper-Kazaz R, Appelhof BC, Posternak MA, Johnson DP, Klibanski A, Lerer B, Fava M. Simultaneous initiation (coinitiation) of pharmacotherapy with triiodothyronine and a selective serotonin reuptake inhibitor for major depressive disorder: a quantitative synthesis of double-blind studies. Int Clin Psychopharmacol. 2009 Jan; 24(1):19-25. PMID: 19092448.
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  355. Friedman ES, Wisniewski SR, Gilmer W, Nierenberg AA, Rush AJ, Fava M, Zisook S, Balasubramani GK, Trivedi MH. Sociodemographic, clinical, and treatment characteristics associated with worsened depression during treatment with citalopram: results of the NIMH STAR(*)D trial. Depress Anxiety. 2009; 26(7):612-21. PMID: 19382183.
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  356. Kornstein SG, Fava M, Jiang Q, Tourian KA. Analysis of depressive symptoms in patients with major depressive disorder treated with desvenlafaxine or placebo. Psychopharmacol Bull. 2009; 42(3):21-35. PMID: 19752839.
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  357. Fava M, Mischoulon D. Folate in depression: efficacy, safety, differences in formulations, and clinical issues. J Clin Psychiatry. 2009; 70 Suppl 5:12-7. PMID: 19909688.
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  358. Dording CM, Sinicropi-Yao L, Papakostas G, Matthews JD, Nierenberg AA, Fava M, Mischoulon D. The response of psychotic-like symptoms to fluoxetine monotherapy in non-psychotic major depressive disorder. Nord J Psychiatry. 2009; 63(5):420-5. PMID: 19521922.
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  359. Morris DW, Trivedi MH, Fava M, Wisniewski SR, Balasubramani GK, Khan AY, Jain S, Rush AJ. Diurnal mood variation in outpatients with major depressive disorder. Depress Anxiety. 2009; 26(9):851-63. PMID: 19306304.
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  360. Bryan C, Songer T, Brooks MM, Thase ME, Gaynes B, Klinkman M, Balasubramani GK, Rush AJ, Trivedi MH, Fava M, Wisniewski SR. Do depressed patients with diabetes experience more side effects when treated with CitalopramThan their counterparts without diabetes? a STAR*D study. Prim Care Companion J Clin Psychiatry. 2009; 11(5):186-96. PMID: 19956455.
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  361. Husain MM, Rush AJ, Wisniewski SR, McClintock SM, Fava M, Nierenberg AA, Davis L, Balasubramani GK, Young E, Albala AA, Trivedi MH. Family history of depression and therapeutic outcome: findings from STAR*D. J Clin Psychiatry. 2009 Feb; 70(2):185-95. PMID: 19192454.
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  363. Evins AE, Culhane MA, Alpert JE, Pava J, Liese BS, Farabaugh A, Fava M. A controlled trial of bupropion added to nicotine patch and behavioral therapy for smoking cessation in adults with unipolar depressive disorders. J Clin Psychopharmacol. 2008 Dec; 28(6):660-6. PMID: 19011435; PMCID: PMC3505846.
  364. Guidi J, Pender M, Hollon SD, Zisook S, Schwartz FH, Pedrelli P, Farabaugh A, Fava M, Petersen TJ. The prevalence of compulsive eating and exercise among college students: an exploratory study. Psychiatry Res. 2009 Jan 30; 165(1-2):154-62. PMID: 19046604.
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  365. McGrath PJ, Khan AY, Trivedi MH, Stewart JW, Morris DW, Wisniewski SR, Miyahara S, Nierenberg AA, Fava M, Rush AJ. Response to a selective serotonin reuptake inhibitor (citalopram) in major depressive disorder with melancholic features: a STAR*D report. J Clin Psychiatry. 2008 Dec; 69(12):1847-55. PMID: 19026268.
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  366. Howland RH, Rush AJ, Wisniewski SR, Trivedi MH, Warden D, Fava M, Davis LL, Balasubramani GK, McGrath PJ, Berman SR. Concurrent anxiety and substance use disorders among outpatients with major depression: clinical features and effect on treatment outcome. Drug Alcohol Depend. 2009 Jan 01; 99(1-3):248-60. PMID: 18986774.
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  367. Pedrelli P, Feldman GC, Vorono S, Fava M, Petersen T. Dysfunctional attitudes and perceived stress predict depressive symptoms severity following antidepressant treatment in patients with chronic depression. Psychiatry Res. 2008 Dec 15; 161(3):302-8. PMID: 18976817.
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  368. Makris N, Gasic GP, Kennedy DN, Hodge SM, Kaiser JR, Lee MJ, Kim BW, Blood AJ, Evins AE, Seidman LJ, Iosifescu DV, Lee S, Baxter C, Perlis RH, Smoller JW, Fava M, Breiter HC. Cortical thickness abnormalities in cocaine addiction--a reflection of both drug use and a pre-existing disposition to drug abuse? Neuron. 2008 Oct 09; 60(1):174-88. PMID: 18940597; PMCID: PMC3772717.
  369. Gelenberg AJ, Thase ME, Meyer RE, Goodwin FK, Katz MM, Kraemer HC, Potter WZ, Shelton RC, Fava M, Khan A, Trivedi MH, Ninan PT, Mann JJ, Bergeson S, Endicott J, Kocsis JH, Leon AC, Manji HK, Rosenbaum JF. The history and current state of antidepressant clinical trial design: a call to action for proof-of-concept studies. J Clin Psychiatry. 2008 Oct; 69(10):1513-28. PMID: 19192434.
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  370. Foster CE, Webster MC, Weissman MM, Pilowsky DJ, Wickramaratne PJ, Talati A, Rush AJ, Hughes CW, Garber J, Malloy E, Cerda G, Kornstein SG, Alpert JE, Wisniewski SR, Trivedi MH, Fava M, King CA. Remission of maternal depression: relations to family functioning and youth internalizing and externalizing symptoms. J Clin Child Adolesc Psychol. 2008 Oct; 37(4):714-24. PMID: 18991123; PMCID: PMC2989174.
  371. Howland RH, Wilson MG, Kornstein SG, Clayton AH, Trivedi MH, Wohlreich MM, Fava M. Factors predicting reduced antidepressant response: experience with the SNRI duloxetine in patients with major depression. Ann Clin Psychiatry. 2008 Oct-Dec; 20(4):209-18. PMID: 19034753.
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  373. Leuchter AF, Lesser IM, Trivedi MH, Rush AJ, Morris DW, Warden D, Fava M, Wisniewski SR, Luther JF, Perales M, Gaynes BN, Stewart JW. An open pilot study of the combination of escitalopram and bupropion-SR for outpatients with major depressive disorder. J Psychiatr Pract. 2008 Sep; 14(5):271-80. PMID: 18832958; PMCID: PMC2778329.
  374. Mischoulon D, Fava M. Are nutritional supplements ready for prime time? J Clin Psychiatry. 2008 Sep; 69(9):1497-8. PMID: 19193349.
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  375. Garakani A, Martinez JM, Marcus S, Weaver J, Rickels K, Fava M, Hirschowitz J. A randomized, double-blind, and placebo-controlled trial of quetiapine augmentation of fluoxetine in major depressive disorder. Int Clin Psychopharmacol. 2008 Sep; 23(5):269-75. PMID: 18703936.
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  376. Foster CE, Webster MC, Weissman MM, Pilowsky DJ, Wickramaratne PJ, Rush AJ, Hughes CW, Garber J, Malloy E, Cerda G, Kornstein SG, Alpert JE, Wisniewski SR, Trivedi MH, Fava M, King CA. Course and Severity of Maternal Depression: Associations with Family Functioning and Child Adjustment. J Youth Adolesc. 2008 Sep; 37(8):906-916. PMID: 25013241.
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  377. Papakostas GI, McGrath P, Stewart J, Charles D, Chen Y, Mischoulon D, Dording C, Fava M. Psychic and somatic anxiety symptoms as predictors of response to fluoxetine in major depressive disorder. Psychiatry Res. 2008 Oct 30; 161(1):116-20. PMID: 18755514.
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  378. Young EA, Kornstein SG, Marcus SM, Harvey AT, Warden D, Wisniewski SR, Balasubramani GK, Fava M, Trivedi MH, John Rush A. Sex differences in response to citalopram: a STAR*D report. J Psychiatr Res. 2009 Feb; 43(5):503-11. PMID: 18752809; PMCID: PMC2681489.
  379. Gilmer WS, Gollan JK, Wisniewski SR, Howland RH, Trivedi MH, Miyahara S, Fleck J, Thase ME, Alpert JE, Nierenberg AA, Warden D, Fava M, Rush AJ. Does the duration of index episode affect the treatment outcome of major depressive disorder? A STAR*D report. J Clin Psychiatry. 2008 Aug; 69(8):1246-56. PMID: 18681756.
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  380. Rush AJ, Wisniewski SR, Warden D, Luther JF, Davis LL, Fava M, Nierenberg AA, Trivedi MH. Selecting among second-step antidepressant medication monotherapies: predictive value of clinical, demographic, or first-step treatment features. Arch Gen Psychiatry. 2008 Aug; 65(8):870-80. PMID: 18678792.
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  381. Papakostas GI, Stahl SM, Krishen A, Seifert CA, Tucker VL, Goodale EP, Fava M. Efficacy of bupropion and the selective serotonin reuptake inhibitors in the treatment of major depressive disorder with high levels of anxiety (anxious depression): a pooled analysis of 10 studies. J Clin Psychiatry. 2008 Aug; 69(8):1287-92. PMID: 18605812.
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  382. Perlis RH, Holt DJ, Smoller JW, Blood AJ, Lee S, Kim BW, Lee MJ, Sun M, Makris N, Kennedy DK, Rooney K, Dougherty DD, Hoge R, Rosenbaum JF, Fava M, Gusella J, Gasic GP, Breiter HC. Association of a polymorphism near CREB1 with differential aversion processing in the insula of healthy participants. Arch Gen Psychiatry. 2008 Aug; 65(8):882-92. PMID: 18678793; PMCID: PMC3782742.
  383. Fava M, Wiltse C, Walker D, Brecht S, Chen A, Perahia D. Predictors of relapse in a study of duloxetine treatment in patients with major depressive disorder. J Affect Disord. 2009 Mar; 113(3):263-71. PMID: 18625521.
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  384. Candrian M, Schwartz F, Farabaugh A, Perlis RH, Ehlert U, Fava M. Personality disorders and perceived stress in major depressive disorder. Psychiatry Res. 2008 Aug 15; 160(2):184-91. PMID: 18573540; PMCID: PMC2553350.
  385. Pilowsky DJ, Wickramaratne P, Talati A, Tang M, Hughes CW, Garber J, Malloy E, King C, Cerda G, Sood AB, Alpert JE, Trivedi MH, Fava M, Rush AJ, Wisniewski S, Weissman MM. Children of depressed mothers 1 year after the initiation of maternal treatment: findings from the STAR*D-Child Study. Am J Psychiatry. 2008 Sep; 165(9):1136-47. PMID: 18558646.
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  386. Mischoulon D, Best-Popescu C, Laposata M, Merens W, Murakami JL, Wu SL, Papakostas GI, Dording CM, Sonawalla SB, Nierenberg AA, Alpert JE, Fava M. A double-blind dose-finding pilot study of docosahexaenoic acid (DHA) for major depressive disorder. Eur Neuropsychopharmacol. 2008 Sep; 18(9):639-45. PMID: 18539007.
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  387. Pizzagalli DA, Iosifescu D, Hallett LA, Ratner KG, Fava M. Reduced hedonic capacity in major depressive disorder: evidence from a probabilistic reward task. J Psychiatr Res. 2008 Nov; 43(1):76-87. PMID: 18433774; PMCID: PMC2637997.
  388. Marcus RN, McQuade RD, Carson WH, Hennicken D, Fava M, Simon JS, Trivedi MH, Thase ME, Berman RM. The efficacy and safety of aripiprazole as adjunctive therapy in major depressive disorder: a second multicenter, randomized, double-blind, placebo-controlled study. J Clin Psychopharmacol. 2008 Apr; 28(2):156-65. PMID: 18344725.
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  389. Nierenberg AA, Ostacher MJ, Huffman JC, Ametrano RM, Fava M, Perlis RH. A brief review of antidepressant efficacy, effectiveness, indications, and usage for major depressive disorder. J Occup Environ Med. 2008 Apr; 50(4):428-36. PMID: 18404015.
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  390. Papakostas GI, Homberger CH, Fava M. A meta-analysis of clinical trials comparing mirtazapine with selective serotonin reuptake inhibitors for the treatment of major depressive disorder. J Psychopharmacol. 2008 Nov; 22(8):843-8. PMID: 18308801.
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  391. Iosifescu DV, Greenwald S, Devlin P, Perlis RH, Denninger JW, Alpert JE, Fava M. Pretreatment frontal EEG and changes in suicidal ideation during SSRI treatment in major depressive disorder. Acta Psychiatr Scand. 2008 Apr; 117(4):271-6. PMID: 18307587.
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  392. Perlis RH, Moorjani P, Fagerness J, Purcell S, Trivedi MH, Fava M, Rush AJ, Smoller JW. Pharmacogenetic analysis of genes implicated in rodent models of antidepressant response: association of TREK1 and treatment resistance in the STAR(*)D study. Neuropsychopharmacology. 2008 Nov; 33(12):2810-9. PMID: 18288090.
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  393. Papakostas GI, Crawford CM, Scalia MJ, Fava M. Timing of clinical improvement and symptom resolution in the treatment of major depressive disorder. A replication of findings with the use of a double-blind, placebo-controlled trial of Hypericum perforatum versus fluoxetine. Neuropsychobiology. 2007; 56(2-3):132-7. PMID: 18259086.
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  394. Gaynes BN, Rush AJ, Trivedi MH, Wisniewski SR, Balasubramani GK, McGrath PJ, Thase ME, Klinkman M, Nierenberg AA, Yates WR, Fava M. Primary versus specialty care outcomes for depressed outpatients managed with measurement-based care: results from STAR*D. J Gen Intern Med. 2008 May; 23(5):551-60. PMID: 18247097; PMCID: PMC2324144.
  395. Harley R, Sprich S, Safren S, Jacobo M, Fava M. Adaptation of dialectical behavior therapy skills training group for treatment-resistant depression. J Nerv Ment Dis. 2008 Feb; 196(2):136-43. PMID: 18277222.
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  396. Iosifescu DV, Bolo NR, Nierenberg AA, Jensen JE, Fava M, Renshaw PF. Brain bioenergetics and response to triiodothyronine augmentation in major depressive disorder. Biol Psychiatry. 2008 Jun 15; 63(12):1127-34. PMID: 18206856.
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  397. Fava M, Rush AJ, Alpert JE, Balasubramani GK, Wisniewski SR, Carmin CN, Biggs MM, Zisook S, Leuchter A, Howland R, Warden D, Trivedi MH. Difference in treatment outcome in outpatients with anxious versus nonanxious depression: a STAR*D report. Am J Psychiatry. 2008 Mar; 165(3):342-51. PMID: 18172020.
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  398. Dunner DL, Wilson M, Fava M, Kornstein S, Munoz R, O'Reardon J, Trivedi M, Wohlreich M. Long-term tolerability and effectiveness of duloxetine in the treatment of major depressive disorder. Depress Anxiety. 2008; 25(5):E1-8. PMID: 17621644.
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  399. Russell JM, Weisberg R, Fava M, Hartford JT, Erickson JS, D'Souza DN. Efficacy of duloxetine in the treatment of generalized anxiety disorder in patients with clinically significant pain symptoms. Depress Anxiety. 2008; 25(7):E1-11. PMID: 17587217.
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  400. Papakostas GI, Fava M. Predictors, moderators, and mediators (correlates) of treatment outcome in major depressive disorder. Dialogues Clin Neurosci. 2008; 10(4):439-51. PMID: 19170401; PMCID: PMC3181892.
  401. Petersen T, Perlis RH, Ticknor C, Lohr J, Solvason HB, O'Reardon JP, Wohlreich MM, Andreotti C, Wilson M, Fava M. Efficacy of duloxetine for the treatment of depression: relationship to most recent antidepressant trial. Psychopharmacol Bull. 2008; 41(1):34-45. PMID: 18362869.
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  402. Gaynes BN, Rush AJ, Trivedi MH, Wisniewski SR, Spencer D, Fava M. The STAR*D study: treating depression in the real world. Cleve Clin J Med. 2008 Jan; 75(1):57-66. PMID: 18236731.
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  403. Thase ME, Trivedi MH, Nelson JC, Fava M, Swanink R, Tran QV, Pikalov A, Yang H, Carlson BX, Marcus RN, Berman RM. Examining the efficacy of adjunctive aripiprazole in major depressive disorder: a pooled analysis of 2 studies. Prim Care Companion J Clin Psychiatry. 2008; 10(6):440-7. PMID: 19287552.
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  404. Perahia DG, Quail D, Desaiah D, Corruble E, Fava M. Switching to duloxetine from selective serotonin reuptake inhibitor antidepressants: a multicenter trial comparing 2 switching techniques. J Clin Psychiatry. 2008 Jan; 69(1):95-105. PMID: 18312043.
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  405. Dording CM, Fisher L, Papakostas G, Farabaugh A, Sonawalla S, Fava M, Mischoulon D. A double-blind, randomized, pilot dose-finding study of maca root (L. meyenii) for the management of SSRI-induced sexual dysfunction. CNS Neurosci Ther. 2008; 14(3):182-91. PMID: 18801111.
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  406. Targum SD, Pollack MH, Fava M. Redefining affective disorders: relevance for drug development. CNS Neurosci Ther. 2008; 14(1):2-9. PMID: 18482094.
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  407. Kozel FA, Trivedi MH, Wisniewski SR, Miyahara S, Husain MM, Fava M, Lebowitz B, Zisook S, Rush AJ. Treatment outcomes for older depressed patients with earlier versus late onset of first depressive episode: a Sequenced Treatment Alternatives to Relieve Depression (STAR*D) report. Am J Geriatr Psychiatry. 2008 Jan; 16(1):58-64. PMID: 18165462.
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  408. Warden D, Rush AJ, Trivedi MH, Fava M, Wisniewski SR. The STAR*D Project results: a comprehensive review of findings. Curr Psychiatry Rep. 2007 Dec; 9(6):449-59. PMID: 18221624.
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  409. Davis LL, Frazier EC, Gaynes BN, Trivedi MH, Wisniewski SR, Fava M, Barkin J, Kashner TM, Shelton RC, Alpert JE, Rush AJ. Are depressed outpatients with and without a family history of substance use disorder different? A baseline analysis of the STAR*D cohort. J Clin Psychiatry. 2007 Dec; 68(12):1931-8. PMID: 18162025.
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  410. Bryan CJ, Songer TJ, Brooks MM, Thase ME, Gaynes BN, Klinkman M, Rush AJ, Trivedi MH, Fava M, Wisniewski SR. A comparison of baseline sociodemographic and clinical characteristics between major depressive disorder patients with and without diabetes: a STAR*D report. J Affect Disord. 2008 May; 108(1-2):113-20. PMID: 18037497.
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  411. Mallinckrodt CH, Prakash A, Houston JP, Swindle R, Detke MJ, Fava M. Differential antidepressant symptom efficacy: placebo-controlled comparisons of duloxetine and SSRIs (fluoxetine, paroxetine, escitalopram). Neuropsychobiology. 2007; 56(2-3):73-85. PMID: 18037817.
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  412. Papakostas GI, Fava M, Thase ME. Treatment of SSRI-resistant depression: a meta-analysis comparing within- versus across-class switches. Biol Psychiatry. 2008 Apr 01; 63(7):699-704. PMID: 17919460.
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  413. Yeung A, Fung F, Yu SC, Vorono S, Ly M, Wu S, Fava M. Validation of the Patient Health Questionnaire-9 for depression screening among Chinese Americans. Compr Psychiatry. 2008 Mar-Apr; 49(2):211-7. PMID: 18243896; PMCID: PMC2268021.
  414. Yeung A, Mischoulon D, Alpert J, Ma Y, Fava M. Acupuncture for major depressive disorder: has its efficacy been disproved? J Clin Psychiatry. 2007 Oct; 68(10):1617; author reply 1617-8. PMID: 17960982.
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  415. Zisook S, Lesser I, Stewart JW, Wisniewski SR, Balasubramani GK, Fava M, Gilmer WS, Dresselhaus TR, Thase ME, Nierenberg AA, Trivedi MH, Rush AJ. Effect of age at onset on the course of major depressive disorder. Am J Psychiatry. 2007 Oct; 164(10):1539-46. PMID: 17898345.
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  416. Candrian M, Farabaugh A, Pizzagalli DA, Baer L, Fava M. Perceived stress and cognitive vulnerability mediate the effects of personality disorder comorbidity on treatment outcome in major depressive disorder: a path analysis study. J Nerv Ment Dis. 2007 Sep; 195(9):729-37. PMID: 17984772.
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  417. Fraguas R, Iosifescu DV, Alpert J, Wisniewski SR, Barkin JL, Trivedi MH, Rush AJ, Fava M. Major depressive disorder and comorbid cardiac disease: is there a depressive subtype with greater cardiovascular morbidity? Results from the STAR*D study. Psychosomatics. 2007 Sep-Oct; 48(5):418-25. PMID: 17878501.
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  418. Morris DW, Rush AJ, Jain S, Fava M, Wisniewski SR, Balasubramani GK, Khan AY, Trivedi MH. Diurnal mood variation in outpatients with major depressive disorder: implications for DSM-V from an analysis of the Sequenced Treatment Alternatives to Relieve Depression Study data. J Clin Psychiatry. 2007 Sep; 68(9):1339-47. PMID: 17915971.
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  419. Simon NM, McNamara K, Chow CW, Maser RS, Papakostas GI, Pollack MH, Nierenberg AA, Fava M, Wong KK. A detailed examination of cytokine abnormalities in Major Depressive Disorder. Eur Neuropsychopharmacol. 2008 Mar; 18(3):230-3. PMID: 17681762; PMCID: PMC2267745.
  420. Matthews JD, Blais M, Park L, Welch C, Baity M, Murakami J, Sklarsky K, Homberger C, Fava M. The impact of galantamine on cognition and mood during electroconvulsive therapy: a pilot study. J Psychiatr Res. 2008 Jun; 42(7):526-31. PMID: 17681545.
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  421. Warden D, Trivedi MH, Wisniewski SR, Davis L, Nierenberg AA, Gaynes BN, Zisook S, Hollon SD, Balasubramani GK, Howland R, Fava M, Stewart JW, Rush AJ. Predictors of attrition during initial (citalopram) treatment for depression: a STAR*D report. Am J Psychiatry. 2007 Aug; 164(8):1189-97. PMID: 17671281.
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  422. Husain MM, Rush AJ, Trivedi MH, McClintock SM, Wisniewski SR, Davis L, Luther JF, Zisook S, Fava M. Pain in depression: STAR*D study findings. J Psychosom Res. 2007 Aug; 63(2):113-22. PMID: 17662746.
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  423. Young EA, Kornstein SG, Harvey AT, Wisniewski SR, Barkin J, Fava M, Trivedi MH, Rush AJ. Influences of hormone-based contraception on depressive symptoms in premenopausal women with major depression. Psychoneuroendocrinology. 2007 Aug; 32(7):843-53. PMID: 17629629.
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  424. Papakostas GI, Charles D, Fava M. Are typical starting doses of the selective serotonin reuptake inhibitors sub-optimal? A meta-analysis of randomized, double-blind, placebo-controlled, dose-finding studies in major depressive disorder. World J Biol Psychiatry. 2007 Jul 13; 1-8. PMID: 17853264.
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  425. Hu XZ, Rush AJ, Charney D, Wilson AF, Sorant AJ, Papanicolaou GJ, Fava M, Trivedi MH, Wisniewski SR, Laje G, Paddock S, McMahon FJ, Manji H, Lipsky RH. Association between a functional serotonin transporter promoter polymorphism and citalopram treatment in adult outpatients with major depression. Arch Gen Psychiatry. 2007 Jul; 64(7):783-92. PMID: 17606812.
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  426. Petersen T, Fava M, Alpert JE, Vorono S, Sanders KM, Mischoulon D. Does psychiatry residency training reflect the "real world" of psychiatry practice? A survey of residency graduates. Acad Psychiatry. 2007 Jul-Aug; 31(4):281-9. PMID: 17626190.
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  427. Fava M, Thase ME, DeBattista C, Doghramji K, Arora S, Hughes RJ. Modafinil augmentation of selective serotonin reuptake inhibitor therapy in MDD partial responders with persistent fatigue and sleepiness. Ann Clin Psychiatry. 2007 Jul-Sep; 19(3):153-9. PMID: 17729016.
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  428. Fava M, Martinez JM, Greist J, Marangell LB, Brown E, Chen L, Wohlreich MM. The efficacy and tolerability of duloxetine in the treatment of anxious versus non-anxious depression: a post-hoc analysis of an open-label outpatient study. Ann Clin Psychiatry. 2007 Jul-Sep; 19(3):187-95. PMID: 17729021.
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  429. Papakostas GI, Thase ME, Fava M, Nelson JC, Shelton RC. Are antidepressant drugs that combine serotonergic and noradrenergic mechanisms of action more effective than the selective serotonin reuptake inhibitors in treating major depressive disorder? A meta-analysis of studies of newer agents. Biol Psychiatry. 2007 Dec 01; 62(11):1217-27. PMID: 17588546.
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  430. Perlis RH, Purcell S, Fava M, Fagerness J, Rush AJ, Trivedi MH, Smoller JW. Association between treatment-emergent suicidal ideation with citalopram and polymorphisms near cyclic adenosine monophosphate response element binding protein in the STAR*D study. Arch Gen Psychiatry. 2007 Jun; 64(6):689-97. PMID: 17548750.
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  431. Papakostas GI, Shelton RC, Smith J, Fava M. Augmentation of antidepressants with atypical antipsychotic medications for treatment-resistant major depressive disorder: a meta-analysis. J Clin Psychiatry. 2007 Jun; 68(6):826-31. PMID: 17592905.
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  432. Thase ME, Friedman ES, Biggs MM, Wisniewski SR, Trivedi MH, Luther JF, Fava M, Nierenberg AA, McGrath PJ, Warden D, Niederehe G, Hollon SD, Rush AJ. Cognitive therapy versus medication in augmentation and switch strategies as second-step treatments: a STAR*D report. Am J Psychiatry. 2007 May; 164(5):739-52. PMID: 17475733.
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  433. Wisniewski SR, Fava M, Trivedi MH, Thase ME, Warden D, Niederehe G, Friedman ES, Biggs MM, Sackeim HA, Shores-Wilson K, McGrath PJ, Lavori PW, Miyahara S, Rush AJ. Acceptability of second-step treatments to depressed outpatients: a STAR*D report. Am J Psychiatry. 2007 May; 164(5):753-60. PMID: 17475734.
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  434. Papakostas GI, Fava M. A meta-analysis of clinical trials comparing the serotonin (5HT)-2 receptor antagonists trazodone and nefazodone with selective serotonin reuptake inhibitors for the treatment of major depressive disorder. Eur Psychiatry. 2007 Oct; 22(7):444-7. PMID: 17418537.
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  435. Lesser IM, Leuchter AF, Trivedi MH, Davis LL, Wisniewski SR, Balasubramani GK, Fava M, Rush AJ. Insured and non-insured depressed outpatients: how do they compare? Ann Clin Psychiatry. 2007 Apr-Jun; 19(2):73-82. PMID: 17612846.
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  436. Fraguas R, Marci C, Fava M, Iosifescu DV, Bankier B, Loh R, Dougherty DD. Autonomic reactivity to induced emotion as potential predictor of response to antidepressant treatment. Psychiatry Res. 2007 May 30; 151(1-2):169-72. PMID: 17360044.
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  437. Gaynes BN, Rush AJ, Trivedi MH, Wisniewski SR, Balasubramani GK, Spencer DC, Petersen T, Klinkman M, Warden D, Nicholas L, Fava M. Major depression symptoms in primary care and psychiatric care settings: a cross-sectional analysis. Ann Fam Med. 2007 Mar-Apr; 5(2):126-34. PMID: 17389536; PMCID: PMC1838683.
  438. Wisniewski SR, Rush AJ, Bryan C, Shelton R, Trivedi MH, Marcus S, Husain MM, Hollon SD, Fava M. Comparison of quality of life measures in a depressed population. J Nerv Ment Dis. 2007 Mar; 195(3):219-25. PMID: 17468681.
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  439. Nierenberg AA, Katz J, Fava M. A critical overview of the pharmacologic management of treatment-resistant depression. Psychiatr Clin North Am. 2007 Mar; 30(1):13-29. PMID: 17362800.
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  440. Moore HK, Wohlreich MM, Wilson MG, Mundt JC, Fava M, Mallinckrodt CH, Greist JH. Using daily interactive voice response assessments: to measure onset of symptom improvement with duloxetine. Psychiatry (Edgmont). 2007 Mar; 4(3):30-8. PMID: 20805908; PMCID: PMC2922356.
  441. Krystal A, Fava M, Rubens R, Wessel T, Caron J, Wilson P, Roth T, McCall WV. Evaluation of eszopiclone discontinuation after cotherapy with fluoxetine for insomnia with coexisting depression. J Clin Sleep Med. 2007 Feb 15; 3(1):48-55. PMID: 17557453.
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  442. Perlis RH, Purcell S, Fagerness J, Cusin C, Yamaki L, Fava M, Smoller JW. Clinical and genetic dissection of anger expression and CREB1 polymorphisms in major depressive disorder. Biol Psychiatry. 2007 Sep 01; 62(5):536-40. PMID: 17300755.
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  443. Fava M, Targum SD. Augmentation and combination strategies to treat the residual symptoms of major depressive disorder. Psychiatry (Edgmont). 2007 Feb; 4(2):16-8. PMID: 20805895; PMCID: PMC2922343.
  444. Peterson TJ, Feldman G, Harley R, Fresco DM, Graves L, Holmes A, Bogdan R, Papakostas GI, Bohn L, Lury RA, Fava M, Segal ZV. Extreme response style in recurrent and chronically depressed patients: change with antidepressant administration and stability during continuation treatment. J Consult Clin Psychol. 2007 Feb; 75(1):145-53. PMID: 17295573.
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  445. Papakostas GI, Hallett LA, Smith J, Tossani E, Mascarini A, Burns AM, Birnbaum RJ, Fava M, Alpert JE. A survey of five antidepressant properties influencing clinician's treatment choices in MDD. Neuropsychiatr Dis Treat. 2007 Feb; 3(1):169-72. PMID: 19300547; PMCID: PMC2654520.
  446. Iosifescu DV, Renshaw PF, Dougherty DD, Lyoo IK, Lee HK, Fraguas R, Cassano P, Nierenberg AA, Fava M. Major depressive disorder with anger attacks and subcortical MRI white matter hyperintensities. J Nerv Ment Dis. 2007 Feb; 195(2):175-8. PMID: 17299307.
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  447. Farabaugh A, Mischoulon D, Schwartz F, Pender M, Fava M, Alpert J. Dysfunctional attitudes and personality disorder comorbidity during long-term treatment of MDD. Depress Anxiety. 2007; 24(6):433-9. PMID: 17086540.
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  448. Cusin C, Fava M, Amsterdam JD, Quitkin FM, Reimherr FW, Beasley CM, Rosenbaum JF, Perlis RH. Early symptomatic worsening during treatment with fluoxetine in major depressive disorder: prevalence and implications. J Clin Psychiatry. 2007 Jan; 68(1):52-7. PMID: 17284130.
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  449. Fava M. Augmenting antidepressants with folate: a clinical perspective. J Clin Psychiatry. 2007; 68 Suppl 10:4-7. PMID: 17900202.
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  450. Fava M. The combination of buspirone and bupropion in the treatment of depression. Psychother Psychosom. 2007; 76(5):311-2. PMID: 17700052.
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  451. Perlis RH, Beasley CM, Wines JD, Tamura RN, Cusin C, Shear D, Amsterdam J, Quitkin F, Strong RE, Rosenbaum JF, Fava M. Treatment-associated suicidal ideation and adverse effects in an open, multicenter trial of fluoxetine for major depressive episodes. Psychother Psychosom. 2007; 76(1):40-6. PMID: 17170562.
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  452. Fraguas R, Iosifescu DV, Bankier B, Perlis R, Clementi-Craven N, Alpert J, Fava M. Major depressive disorder with anger attacks and cardiovascular risk factors. Int J Psychiatry Med. 2007; 37(1):99-111. PMID: 17645202.
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  453. Yates WR, Mitchell J, John Rush A, Trivedi M, Wisniewski SR, Warden D, Bryan C, Fava M, Husain MM, Gaynes BN. Clinical features of depression in outpatients with and without co-occurring general medical conditions in STAR*D: confirmatory analysis. Prim Care Companion J Clin Psychiatry. 2007; 9(1):7-15. PMID: 17599162; PMCID: PMC1894838.
  454. Papakostas GI, Petersen T, Homberger CH, Green CH, Smith J, Alpert JE, Fava M. Hopelessness as a predictor of non-response to fluoxetine in major depressive disorder. Ann Clin Psychiatry. 2007 Jan-Mar; 19(1):5-8. PMID: 17453655.
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  455. Papakostas GI, Perlis RH, Seifert C, Fava M. Antidepressant dose reduction and the risk of relapse in major depressive disorder. Psychother Psychosom. 2007; 76(5):266-70. PMID: 17700046.
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  456. Papakostas GI, Petersen T, Sklarsky KG, Nierenberg AA, Alpert JE, Fava M. Timing of clinical improvement and symptom resolution in the treatment of major depressive disorder. Psychiatry Res. 2007 Jan 15; 149(1-3):195-200. PMID: 17157390.
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  457. Fava M, Graves LM, Benazzi F, Scalia MJ, Iosifescu DV, Alpert JE, Papakostas GI. A cross-sectional study of the prevalence of cognitive and physical symptoms during long-term antidepressant treatment. J Clin Psychiatry. 2006 Nov; 67(11):1754-9. PMID: 17196056.
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  458. Fava M, Rush AJ, Alpert JE, Carmin CN, Balasubramani GK, Wisniewski SR, Trivedi MH, Biggs MM, Shores-Wilson K. What clinical and symptom features and comorbid disorders characterize outpatients with anxious major depressive disorder: a replication and extension. Can J Psychiatry. 2006 Nov; 51(13):823-35. PMID: 17195602.
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  459. Rush AJ, Trivedi MH, Wisniewski SR, Nierenberg AA, Stewart JW, Warden D, Niederehe G, Thase ME, Lavori PW, Lebowitz BD, McGrath PJ, Rosenbaum JF, Sackeim HA, Kupfer DJ, Luther J, Fava M. Acute and longer-term outcomes in depressed outpatients requiring one or several treatment steps: a STAR*D report. Am J Psychiatry. 2006 Nov; 163(11):1905-17. PMID: 17074942.
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  460. Papakostas GI, Fava M. A metaanalysis of clinical trials comparing moclobemide with selective serotonin reuptake inhibitors for the treatment of major depressive disorder. Can J Psychiatry. 2006 Oct; 51(12):783-90. PMID: 17168253.
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  461. Yeung A, Yu SC, Fung F, Vorono S, Fava M. Recognizing and engaging depressed Chinese Americans in treatment in a primary care setting. Int J Geriatr Psychiatry. 2006 Sep; 21(9):819-23. PMID: 16955440.
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  462. McGrath PJ, Stewart JW, Quitkin FM, Chen Y, Alpert JE, Nierenberg AA, Fava M, Cheng J, Petkova E. Predictors of relapse in a prospective study of fluoxetine treatment of major depression. Am J Psychiatry. 2006 Sep; 163(9):1542-8. PMID: 16946178.
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  463. Nierenberg AA, Fava M, Trivedi MH, Wisniewski SR, Thase ME, McGrath PJ, Alpert JE, Warden D, Luther JF, Niederehe G, Lebowitz B, Shores-Wilson K, Rush AJ. A comparison of lithium and T(3) augmentation following two failed medication treatments for depression: a STAR*D report. Am J Psychiatry. 2006 Sep; 163(9):1519-30; quiz 1665. PMID: 16946176.
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  464. McGrath PJ, Stewart JW, Fava M, Trivedi MH, Wisniewski SR, Nierenberg AA, Thase ME, Davis L, Biggs MM, Shores-Wilson K, Luther JF, Niederehe G, Warden D, Rush AJ. Tranylcypromine versus venlafaxine plus mirtazapine following three failed antidepressant medication trials for depression: a STAR*D report. Am J Psychiatry. 2006 Sep; 163(9):1531-41; quiz 1666. PMID: 16946177.
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  465. Trivedi MH, Fava M, Marangell LB, Osser DN, Shelton RC. Use of treatment algorithms for depression. J Clin Psychiatry. 2006 Sep; 67(9):1458-65. PMID: 17017835.
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  466. Papakostas GI, Nutt DJ, Hallett LA, Tucker VL, Krishen A, Fava M. Resolution of sleepiness and fatigue in major depressive disorder: A comparison of bupropion and the selective serotonin reuptake inhibitors. Biol Psychiatry. 2006 Dec 15; 60(12):1350-5. PMID: 16934768.
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  467. Fava M, Rush AJ, Wisniewski SR, Nierenberg AA, Alpert JE, McGrath PJ, Thase ME, Warden D, Biggs M, Luther JF, Niederehe G, Ritz L, Trivedi MH. A comparison of mirtazapine and nortriptyline following two consecutive failed medication treatments for depressed outpatients: a STAR*D report. Am J Psychiatry. 2006 Jul; 163(7):1161-72. PMID: 16816220.
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  468. Denninger JW, Papakostas GI, Mahal Y, Merens W, Alpert JE, Nierenberg AA, Yeung A, Fava M. Somatic symptoms in outpatients with major depressive disorder treated with fluoxetine. Psychosomatics. 2006 Jul-Aug; 47(4):348-52. PMID: 16844895.
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  469. Davis LL, Frazier E, Husain MM, Warden D, Trivedi M, Fava M, Cassano P, McGrath PJ, Balasubramani GK, Wisniewski SR, Rush AJ. Substance use disorder comorbidity in major depressive disorder: a confirmatory analysis of the STAR*D cohort. Am J Addict. 2006 Jul-Aug; 15(4):278-85. PMID: 16867922.
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  470. Rush AJ, Kraemer HC, Sackeim HA, Fava M, Trivedi MH, Frank E, Ninan PT, Thase ME, Gelenberg AJ, Kupfer DJ, Regier DA, Rosenbaum JF, Ray O, Schatzberg AF. Report by the ACNP Task Force on response and remission in major depressive disorder. Neuropsychopharmacology. 2006 Sep; 31(9):1841-53. PMID: 16794566.
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  471. Papakostas GI, Fava M. A meta-analysis of clinical trials comparing milnacipran, a serotonin--norepinephrine reuptake inhibitor, with a selective serotonin reuptake inhibitor for the treatment of major depressive disorder. Eur Neuropsychopharmacol. 2007 Jan; 17(1):32-6. PMID: 16762534.
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  472. Farabaugh AH, Sonawalla SB, Fava M, Pedrelli P, Papakostas GI, Schwartz F, Mischoulon D. Differences in cognitive factors between "true drug" versus "placebo pattern" response to fluoxetine as defined by pattern analysis. Hum Psychopharmacol. 2006 Jun; 21(4):221-5. PMID: 16783809.
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  473. Kessler RC, Coccaro EF, Fava M, Jaeger S, Jin R, Walters E. The prevalence and correlates of DSM-IV intermittent explosive disorder in the National Comorbidity Survey Replication. Arch Gen Psychiatry. 2006 Jun; 63(6):669-78. PMID: 16754840.
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  474. Papakostas GI, Miller KK, Petersen T, Sklarsky KG, Hilliker SE, Klibanski A, Fava M. Serum prolactin levels among outpatients with major depressive disorder during the acute phase of treatment with fluoxetine. J Clin Psychiatry. 2006 Jun; 67(6):952-7. PMID: 16848655.
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  475. Nierenberg AA, Trivedi MH, Fava M, Biggs MM, Shores-Wilson K, Wisniewski SR, Balasubramani GK, Rush AJ. Family history of mood disorder and characteristics of major depressive disorder: a STAR*D (sequenced treatment alternatives to relieve depression) study. J Psychiatr Res. 2007 Apr-Jun; 41(3-4):214-21. PMID: 16690084.
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  476. Fava M, Detke MJ, Balestrieri M, Wang F, Raskin J, Perahia D. Management of depression relapse: re-initiation of duloxetine treatment or dose increase. J Psychiatr Res. 2006 Jun; 40(4):328-36. PMID: 16678205.
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  477. Fava M. Pharmacological approaches to the treatment of residual symptoms. J Psychopharmacol. 2006 May; 20(3 Suppl):29-34. PMID: 16644769.
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  478. Simon NM, Smoller JW, McNamara KL, Maser RS, Zalta AK, Pollack MH, Nierenberg AA, Fava M, Wong KK. Telomere shortening and mood disorders: preliminary support for a chronic stress model of accelerated aging. Biol Psychiatry. 2006 Sep 01; 60(5):432-5. PMID: 16581033.
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  479. Fava M, McCall WV, Krystal A, Wessel T, Rubens R, Caron J, Amato D, Roth T. Eszopiclone co-administered with fluoxetine in patients with insomnia coexisting with major depressive disorder. Biol Psychiatry. 2006 Jun 01; 59(11):1052-60. PMID: 16581036.
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  480. Khan AY, Carrithers J, Preskorn SH, Lear R, Wisniewski SR, John Rush A, Stegman D, Kelley C, Kreiner K, Nierenberg AA, Fava M. Clinical and demographic factors associated with DSM-IV melancholic depression. Ann Clin Psychiatry. 2006 Apr-Jun; 18(2):91-8. PMID: 16754414.
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  481. Papakostas GI, Petersen TJ, Perlis RH, Judy AE, Burns AM, Alpert JE, Birnbaum RJ, Fava M. A survey of antidepressant prescribing practices in major depression with comorbid attention-deficit hyperactivity disorder. J Clin Psychopharmacol. 2006 Apr; 26(2):216-8. PMID: 16633159.
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  482. Rush AJ, Trivedi MH, Wisniewski SR, Stewart JW, Nierenberg AA, Thase ME, Ritz L, Biggs MM, Warden D, Luther JF, Shores-Wilson K, Niederehe G, Fava M. Bupropion-SR, sertraline, or venlafaxine-XR after failure of SSRIs for depression. N Engl J Med. 2006 Mar 23; 354(12):1231-42. PMID: 16554525.
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  483. Trivedi MH, Fava M, Wisniewski SR, Thase ME, Quitkin F, Warden D, Ritz L, Nierenberg AA, Lebowitz BD, Biggs MM, Luther JF, Shores-Wilson K, Rush AJ. Medication augmentation after the fa