Title Oscar M. Schloss, MD Professor of Pediatrics, Professor of Biological Chemistry and Molecular Pharmacology Institution Boston Children's Hospital Address Children's Hospital
C L S B 3095
3 Blackfan Circle
Boston MA 02115
|
|
Title
Oscar M. Schloss, MD Professor of Pediatrics
Institution
Boston Children's Hospital
Overview
The Hur laboratory investigates molecular mechanisms of self and non-self discrimination by the immune systems. The lab currently focuses on two topics: (1) the innate immune receptors involved in antiviral immune response, and (2) the transcription factors involved in T cell development of self tolerance. The lab uses a combination of structural biology, biochemistry and cell biology to identify molecular principles governing these key immunological processes. Visit http://hurlab.tch.harvard.edu/
Research
The research activities and funding listed below are automatically derived from
NIH ExPORTER and other sources, which might result in incorrect or missing items.
Faculty can
login
to make corrections and additions.
-
R01AI154653
(HUR, SUN)
Jul 1, 2020 - Jun 30, 2025
Molecular mechanisms for antiviral signaling and regulation by MDA5 and TRIM65
Role: Principal Investigator
-
DP1AI152074
(HUR, SUN)
Sep 30, 2019 - Jul 31, 2024
Resolving functional aggregates: A new perspective on innate immune control
Role: Principal Investigator
-
R21AI147099
(HUR, SUN)
Jun 10, 2019 - May 31, 2021
Defining the molecular mechanism of Aire in T-cell tolerance
Role: Principal Investigator
-
R21AI130791
(HUR, SUN)
Jan 20, 2017 - Dec 31, 2018
Re-defining RIG-I-like helicases as viral RNA receptors with effector functions
Role: Principal Investigator
-
R21AI119880
(HUR, SUN)
Jun 26, 2015 - May 31, 2017
Interplays between ADAR1 and MDA5 in the pathogenesis of Aicardi-Goutière Syndrome
Role: Principal Investigator
-
R01AI111784
(HUR, SUN)
Sep 17, 2014 - Aug 31, 2024
Molecular mechanism of RIG-I and RIPLET in antiviral signaling
Role: Principal Investigator
-
R01AI106912
(HUR, SUN)
May 15, 2014 - Apr 30, 2019
Molecular Mechanisms for Antiviral Signal Activation by MDA5 and RIG-I
Role: Principal Investigator
Bibliographic
Local representatives can answer questions about the Profiles website or help with editing a profile or issues with profile data. For assistance with this profile: HMS/HSDM faculty should contact contactcatalyst.harvard.edu. For faculty or fellow appointment updates and changes, please ask your appointing department to contact HMS. For fellow personal and demographic information, contact HMS Human Resources at human_resourceshms.harvard.edu. For faculty personal and demographic information, contact HMS Office for Faculty Affairs at facappthms.harvard.edu.