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Jonathan Zheng Li, M.D.

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Research
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. R01AI150396 (LI, JONATHAN) Jan 7, 2020 - Dec 31, 2024
    NIH
    HIV Reservoir Ecology of Viral Remission
    Role: Principal Investigator
  2. R01AI138801 (LI, JONATHAN) Jul 6, 2018 - Jun 30, 2022
    NIH
    Novel virologic and pharmacologic assays to predict clinical outcomes after first-line ART failure in sub-Saharan Africa
    Role: Principal Investigator
  3. R56AI125109 (LI, JONATHAN) Aug 1, 2016 - Jul 31, 2018
    NIH
    Viral and Immune Determinants of HIV Rebound
    Role: Principal Investigator
  4. R21AI127079 (LI, JONATHAN) Jun 20, 2016 - May 31, 2019
    NIH
    Single-Cell Analysis of HIV Latency Reversal
    Role: Principal Investigator
  5. R21AI124859 (CASTILLO-MANCILLA, JOSE RAMON) Mar 15, 2016 - Feb 28, 2018
    NIH
    Impact of ART Adherence on HIV Persistence and Inflammation
    Role: Co-Principal Investigator

Featured Content

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Li Y, Etemad B, Dele-Oni R, Sharaf R, Gao C, Lichterfeld M, Li JZ. Drug resistance mutations in HIV provirus are associated with defective proviral genomes with hypermutation. AIDS. 2021 Jun 01; 35(7):1015-1020. PMID: 33635848.
    Citations:    Fields:    
  2. Ramirez JA, Maddali MV, Nematollahi S, Li JZ, Shah M. New Strategies in Clinical Guideline Delivery: Randomized Trial of Online, Interactive Decision Support Versus Guidelines for Human Immunodeficiency Virus Treatment Selection by Trainees. Clin Infect Dis. 2021 May 04; 72(9):1608-1614. PMID: 32211758.
    Citations:    Fields:    
  3. Choudhary MC, Crain CR, Qiu X, Hanage W, Li JZ. SARS-CoV-2 Sequence Characteristics of COVID-19 Persistence and Reinfection. Clin Infect Dis. 2021 Apr 27. PMID: 33906227.
    Citations:    Fields:    
  4. Harb H, Benamar M, Lai PS, Contini P, Griffith JW, Crestani E, Schmitz-Abe K, Chen Q, Fong J, Marri L, Filaci G, Del Zotto G, Pishesha N, Kolifrath S, Broggi A, Ghosh S, Gelmez MY, Oktelik FB, Cetin EA, Kiykim A, Kose M, Wang Z, Cui Y, Yu XG, Li JZ, Berra L, Stephen-Victor E, Charbonnier LM, Zanoni I, Ploegh H, Deniz G, De Palma R, Chatila TA. Notch4 signaling limits regulatory T-cell-mediated tissue repair and promotes severe lung inflammation in viral infections. Immunity. 2021 Apr 22. PMID: 33915108.
    Citations:    Fields:    
  5. Conway JM, Meily P, Li JZ, Perelson AS. Unified model of short- and long-term HIV viral rebound for clinical trial planning. J R Soc Interface. 2021 04; 18(177):20201015. PMID: 33849338.
    Citations:    Fields:    
  6. Bordt EA, Shook LL, Atyeo C, Pullen KM, De Guzman RM, Meinsohn MC, Chauvin M, Fischinger S, Yockey LJ, James K, Lima R, Yonker LM, Fasano A, Brigida S, Bebell LM, Roberts DJ, Pépin D, Huh JR, Bilbo SD, Li JZ, Kaimal A, Schust D, Gray KJ, Lauffenburger D, Alter G, Edlow AG. Sexually dimorphic placental responses to maternal SARS-CoV-2 infection. bioRxiv. 2021 Mar 29. PMID: 33821279.
    Citations:    
  7. Kaneko N, Boucau J, Kuo HH, Perugino C, Mahajan VS, Farmer JR, Liu H, Diefenbach TJ, Piechocka-Trocha A, Lefteri K, Waring MT, Premo KR, Walker BD, Li JZ, Gaiha G, Yu XG, Lichterfeld M, Padera RF, Pillai S. Expansion of Cytotoxic CD4+ T cells in the lungs in severe COVID-19. medRxiv. 2021 Mar 26. PMID: 33791730.
    Citations:    
  8. Ter-Ovanesyan D, Gilboa T, Lazarovits R, Rosenthal A, Yu X, Li JZ, Church GM, Walt DR. Ultrasensitive Measurement of Both SARS-CoV-2 RNA and Antibodies from Saliva. Anal Chem. 2021 04 06; 93(13):5365-5370. PMID: 33755419.
    Citations:    Fields:    Translation:Humans
  9. Clark SA, Clark LE, Pan J, Coscia A, McKay LGA, Shankar S, Johnson RI, Brusic V, Choudhary MC, Regan J, Li JZ, Griffiths A, Abraham J. SARS-CoV-2 evolution in an immunocompromised host reveals shared neutralization escape mechanisms. Cell. 2021 Mar 16. PMID: 33831372.
    Citations:    Fields:    
  10. Kim MH, Salloum S, Wang JY, Wong LP, Regan J, Lefteri K, Manickas-Hill Z, Li JZ, Sadreyev RI, Yu XG, Chung RT. Type I, II, and III interferon signatures correspond to COVID-19 disease severity. medRxiv. 2021 Mar 12. PMID: 33758894.
    Citations:    
  11. Li JZ, Stella N, Choudhary MC, Javed A, Rodriguez K, Ribaudo H, Moosa MY, Brijkumar J, Pillay S, Sunpath H, Noguera-Julian M, Paredes R, Johnson B, Edwards A, Marconi VC, Kuritzkes DR. Impact of pre-existing drug resistance on risk of virological failure in South Africa. J Antimicrob Chemother. 2021 Mar 10. PMID: 33693678.
    Citations:    Fields:    
  12. Bartsch YC, Loos C, Rossignol E, Fajnzylber JM, Yuan D, Avihingsanon A, Ubolyam S, Jupimai T, Hirschel B, Ananworanich J, Lauffenburger DA, Li JZ, Alter G, Julg B. Viral Rebound Kinetics Correlate with Distinct HIV Antibody Features. mBio. 2021 03 09; 12(2). PMID: 33688003.
    Citations:    Fields:    
  13. Li Y, Schneider AM, Mehta A, Sade-Feldman M, Kays KR, Gentili M, Charland NC, Gonye ALK, Gushterova I, Khanna HK, LaSalle TJ, Lavin-Parsons KM, Lilly BM, Lodenstein CL, Manakongtreecheep K, Margolin JD, McKaig BN, Parry BA, Rojas-Lopez M, Russo BC, Sharma N, Tantivit J, Thomas MF, Regan J, Flynn JP, Villani AC, Hacohen N, Goldberg MB, Filbin MR, Li JZ. SARS-CoV-2 Viremia is Associated with Distinct Proteomic Pathways and Predicts COVID-19 Outcomes. medRxiv. 2021 Feb 26. PMID: 33655257.
    Citations:    
  14. Giron LB, Papasavvas E, Yin X, Goldman AR, Tang HY, Palmer CS, Landay AL, Li JZ, Koethe JR, Mounzer K, Kostman JR, Liu Q, Montaner LJ, Abdel-Mohsen M. Phospholipid Metabolism Is Associated with Time to HIV Rebound upon Treatment Interruption. mBio. 2021 02 23; 12(1). PMID: 33622719.
    Citations:    Fields:    
  15. Diepstra KL, Barr L, Palm D, Hogg E, Mollan KR, Henley L, Stover AM, Simoni JM, Sugarman J, Brown B, Sauceda JA, Deeks S, Fox L, Gandhi RT, Smith D, Li JZ, Dubé K. Participant Perspectives and Experiences Entering an Intensively Monitored Antiretroviral Pause: Results from the AIDS Clinical Trials Group A5345 Biomarker Study. AIDS Res Hum Retroviruses. 2021 Feb 16. PMID: 33472545.
    Citations:    Fields:    
  16. Li Y, Mohammadi A, Li JZ. Challenges and Promise of Human Immunodeficiency Virus Remission. J Infect Dis. 2021 Feb 15; 223(Supplement_1):4-12. PMID: 33586773.
    Citations:    Fields:    
  17. Li JZ, Gandhi RT. The Search for an HIV Cure: Where Do We Go From Here? J Infect Dis. 2021 Feb 15; 223(Supplement_1):1-3. PMID: 33586774.
    Citations:    Fields:    
  18. Lemieux JE, Li JZ. Uncovering Ways that Emerging SARS-CoV-2 Lineages May Increase Transmissibility. J Infect Dis. 2021 Feb 13. PMID: 33580264.
    Citations:    Fields:    
  19. Starr TN, Greaney AJ, Addetia A, Hannon WW, Choudhary MC, Dingens AS, Li JZ, Bloom JD. Prospective mapping of viral mutations that escape antibodies used to treat COVID-19. Science. 2021 02 19; 371(6531):850-854. PMID: 33495308.
    Citations: 28     Fields:    Translation:HumansCells
  20. Silverstein NJ, Wang Y, Manickas-Hill Z, Carbone CC, Dauphin A, Li JZ, Walker BD, Yu XG, Luban J. Innate lymphoid cells and disease tolerance in SARS-CoV-2 infection. medRxiv. 2021 Jan 15. PMID: 33469605.
    Citations:    
  21. Li Y, Regan J, Fajnzylber J, Coxen K, Corry H, Wong C, Rosenthal A, Atyeo C, Fischinger S, Gillespie E, Chishti R, Baden L, Yu XG, Alter G, Kim A, Li JZ. Liver Fibrosis Index FIB-4 Is Associated With Mortality in COVID-19. Hepatol Commun. 2020 Dec 10. PMID: 33363264.
    Citations:    
  22. Starr TN, Greaney AJ, Addetia A, Hannon WW, Choudhary MC, Dingens AS, Li JZ, Bloom JD. Prospective mapping of viral mutations that escape antibodies used to treat COVID-19. bioRxiv. 2020 Dec 01. PMID: 33299993.
    Citations:    
  23. Edlow AG, Li JZ, Collier AY, Atyeo C, James KE, Boatin AA, Gray KJ, Bordt EA, Shook LL, Yonker LM, Fasano A, Diouf K, Croul N, Devane S, Yockey LJ, Lima R, Shui J, Matute JD, Lerou PH, Akinwunmi BO, Schmidt A, Feldman J, Hauser BM, Caradonna TM, De la Flor D, D'Avino P, Regan J, Corry H, Coxen K, Fajnzylber J, Pepin D, Seaman MS, Barouch DH, Walker BD, Yu XG, Kaimal AJ, Roberts DJ, Alter G. Assessment of Maternal and Neonatal SARS-CoV-2 Viral Load, Transplacental Antibody Transfer, and Placental Pathology in Pregnancies During the COVID-19 Pandemic. JAMA Netw Open. 2020 12 01; 3(12):e2030455. PMID: 33351086.
    Citations: 15     Fields:    Translation:HumansCells
  24. Shokr A, Pacheco LGC, Thirumalaraju P, Kanakasabapathy MK, Gandhi J, Kartik D, Silva FSR, Erdogmus E, Kandula H, Luo S, Yu XG, Chung RT, Li JZ, Kuritzkes DR, Shafiee H. Mobile Health (mHealth) Viral Diagnostics Enabled with Adaptive Adversarial Learning. ACS Nano. 2021 01 26; 15(1):665-673. PMID: 33226787.
    Citations:    Fields:    Translation:HumansPHPublic Health
  25. Qian J, Boswell SA, Chidley C, Lu ZX, Pettit ME, Gaudio BL, Fajnzylber JM, Ingram RT, Ward RH, Li JZ, Springer M. An enhanced isothermal amplification assay for viral detection. Nat Commun. 2020 11 20; 11(1):5920. PMID: 33219228.
    Citations: 6     Fields:    Translation:HumansCells
  26. Choi B, Choudhary MC, Regan J, Sparks JA, Padera RF, Qiu X, Solomon IH, Kuo HH, Boucau J, Bowman K, Adhikari UD, Winkler ML, Mueller AA, Hsu TY, Desjardins M, Baden LR, Chan BT, Walker BD, Lichterfeld M, Brigl M, Kwon DS, Kanjilal S, Richardson ET, Jonsson AH, Alter G, Barczak AK, Hanage WP, Yu XG, Gaiha GD, Seaman MS, Cernadas M, Li JZ. Persistence and Evolution of SARS-CoV-2 in an Immunocompromised Host. N Engl J Med. 2020 12 03; 383(23):2291-2293. PMID: 33176080.
    Citations: 48     Fields:    Translation:Humans
  27. Siddiqi HK, Weber B, Zhou G, Regan J, Fajnzylber J, Coxen K, Corry H, Yu XG, DiCarli M, Li JZ, Bhatt DL. Increased Prevalence of Myocardial Injury in Patients with SARS-CoV-2 Viremia. Am J Med. 2021 04; 134(4):542-546. PMID: 33181107.
    Citations:    Fields:    
  28. Jilg N, Garcia-Broncano P, Peluso M, Segal FP, Bosch RJ, Roberts-Toler C, Chen SMY, Van Dam CN, Keefer MC, Kuritzkes DR, Landay AL, Deeks S, Yu XG, Sax PE, Li JZ. Maintenance of Viral Suppression in Human Immunodeficiency Virus Controllers Despite Waning T-Cell Responses During Antiretroviral Therapy. J Infect Dis. 2020 11 09; 222(11):1837-1842. PMID: 32496516.
    Citations:    Fields:    Translation:HumansCells
  29. Fajnzylber J, Regan J, Coxen K, Corry H, Wong C, Rosenthal A, Worrall D, Giguel F, Piechocka-Trocha A, Atyeo C, Fischinger S, Chan A, Flaherty KT, Hall K, Dougan M, Ryan ET, Gillespie E, Chishti R, Li Y, Jilg N, Hanidziar D, Baron RM, Baden L, Tsibris AM, Armstrong KA, Kuritzkes DR, Alter G, Walker BD, Yu X, Li JZ. SARS-CoV-2 viral load is associated with increased disease severity and mortality. Nat Commun. 2020 10 30; 11(1):5493. PMID: 33127906.
    Citations: 32     Fields:    Translation:HumansCellsPHPublic Health
  30. Shrock E, Fujimura E, Kula T, Timms RT, Lee IH, Leng Y, Robinson ML, Sie BM, Li MZ, Chen Y, Logue J, Zuiani A, McCulloch D, Lelis FJN, Henson S, Monaco DR, Travers M, Habibi S, Clarke WA, Caturegli P, Laeyendecker O, Piechocka-Trocha A, Li JZ, Khatri A, Chu HY, Villani AC, Kays K, Goldberg MB, Hacohen N, Filbin MR, Yu XG, Walker BD, Wesemann DR, Larman HB, Lederer JA, Elledge SJ. Viral epitope profiling of COVID-19 patients reveals cross-reactivity and correlates of severity. Science. 2020 11 27; 370(6520). PMID: 32994364.
    Citations: 38     Fields:    Translation:HumansCells
  31. Yonker LM, Neilan AM, Bartsch Y, Patel AB, Regan J, Arya P, Gootkind E, Park G, Hardcastle M, St John A, Appleman L, Chiu ML, Fialkowski A, De La Flor D, Lima R, Bordt EA, Yockey LJ, D'Avino P, Fischinger S, Shui JE, Lerou PH, Bonventre JV, Yu XG, Ryan ET, Bassett IV, Irimia D, Edlow AG, Alter G, Li JZ, Fasano A. Reply. J Pediatr. 2021 01; 228:317-319. PMID: 32971143.
    Citations:    Fields:    
  32. Yonker LM, Neilan AM, Bartsch Y, Patel AB, Regan J, Arya P, Gootkind E, Park G, Hardcastle M, St John A, Appleman L, Chiu ML, Fialkowski A, De la Flor D, Lima R, Bordt EA, Yockey LJ, D'Avino P, Fischinger S, Shui JE, Lerou PH, Bonventre JV, Yu XG, Ryan ET, Bassett IV, Irimia D, Edlow AG, Alter G, Li JZ, Fasano A. Reply. J Pediatr. 2021 01; 228:320-323. PMID: 32956696.
    Citations:    Fields:    
  33. Joung J, Ladha A, Saito M, Kim NG, Woolley AE, Segel M, Barretto RPJ, Ranu A, Macrae RK, Faure G, Ioannidi EI, Krajeski RN, Bruneau R, Huang MW, Yu XG, Li JZ, Walker BD, Hung DT, Greninger AL, Jerome KR, Gootenberg JS, Abudayyeh OO, Zhang F. Detection of SARS-CoV-2 with SHERLOCK One-Pot Testing. N Engl J Med. 2020 10 08; 383(15):1492-1494. PMID: 32937062.
    Citations: 34     Fields:    Translation:HumansCellsPHPublic Health
  34. Li JZ, Sears CL, Chatterjee A. Empowering Inclusion and Diversity in the Field of Infectious Diseases. J Infect Dis. 2020 09 14; 222(Suppl 6):S521-S522. PMID: 32926741.
    Citations:    Fields:    Translation:Humans
  35. Li JZ, Yu XG. Overcoming Challenges in Coronavirus Disease 19 Translational Research. J Infect Dis. 2020 09 14; 222(8):1254-1255. PMID: 32772113.
    Citations:    Fields:    Translation:HumansCellsPHPublic Health
  36. Yue H, Nowak RP, Overwijn D, Payne NC, Fischinger S, Atyeo C, Baden LR, Nilles EJ, Karlson EW, Yu XG, Li JZ, Alter G, Mazitschek R, Fischer ES. Rapid 'mix and read' assay for scalable detection of SARS-CoV-2 antibodies in patient plasma. medRxiv. 2020 Sep 03. PMID: 32909004.
    Citations:    
  37. Shook LL, Shui JE, Boatin AA, Devane S, Croul N, Yonker LM, Matute JD, Lima RS, Schwinn M, Cvrk D, Gardner L, Azevedo R, Stanton S, Bordt EA, Yockey LJ, Fasano A, Li JZ, Yu XG, Kaimal AJ, Lerou PH, Edlow AG. Rapid establishment of a COVID-19 perinatal biorepository: early lessons from the first 100 women enrolled. BMC Med Res Methodol. 2020 08 26; 20(1):215. PMID: 32842979.
    Citations: 2     Fields:    Translation:HumansCellsPHPublic Health
  38. Yonker LM, Neilan AM, Bartsch Y, Patel AB, Regan J, Arya P, Gootkind E, Park G, Hardcastle M, St John A, Appleman L, Chiu ML, Fialkowski A, De la Flor D, Lima R, Bordt EA, Yockey LJ, D'Avino P, Fischinger S, Shui JE, Lerou PH, Bonventre JV, Yu XG, Ryan ET, Bassett IV, Irimia D, Edlow AG, Alter G, Li JZ, Fasano A. Pediatric Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2): Clinical Presentation, Infectivity, and Immune Responses. J Pediatr. 2020 12; 227:45-52.e5. PMID: 32827525.
    Citations: 41     Fields:    Translation:HumansPHPublic Health
  39. Kaneko N, Kuo HH, Boucau J, Farmer JR, Allard-Chamard H, Mahajan VS, Piechocka-Trocha A, Lefteri K, Osborn M, Bals J, Bartsch YC, Bonheur N, Caradonna TM, Chevalier J, Chowdhury F, Diefenbach TJ, Einkauf K, Fallon J, Feldman J, Finn KK, Garcia-Broncano P, Hartana CA, Hauser BM, Jiang C, Kaplonek P, Karpell M, Koscher EC, Lian X, Liu H, Liu J, Ly NL, Michell AR, Rassadkina Y, Seiger K, Sessa L, Shin S, Singh N, Sun W, Sun X, Ticheli HJ, Waring MT, Zhu AL, Alter G, Li JZ, Lingwood D, Schmidt AG, Lichterfeld M, Walker BD, Yu XG, Padera RF, Pillai S. Loss of Bcl-6-Expressing T Follicular Helper Cells and Germinal Centers in COVID-19. Cell. 2020 10 01; 183(1):143-157.e13. PMID: 32877699.
    Citations: 75     Fields:    Translation:HumansCellsPHPublic Health
  40. Mohammadi A, Esmaeilzadeh E, Li Y, Bosch RJ, Li JZ. SARS-CoV-2 detection in different respiratory sites: A systematic review and meta-analysis. EBioMedicine. 2020 Sep; 59:102903. PMID: 32718896.
    Citations: 36     Fields:    Translation:HumansCellsPHPublic Health
  41. Qian J, Boswell SA, Chidley C, Lu ZX, Pettit ME, Gaudio BL, Fajnzylber JM, Ingram RT, Ward RH, Li JZ, Springer M. An enhanced isothermal amplification assay for viral detection. bioRxiv. 2020 May 29. PMID: 32577657.
    Citations: 1     
  42. Andrade VM, Mavian C, Babic D, Cordeiro T, Sharkey M, Barrios L, Brander C, Martinez-Picado J, Dalmau J, Llano A, Li JZ, Jacobson J, Lavine CL, Seaman MS, Salemi M, Stevenson M. A minor population of macrophage-tropic HIV-1 variants is identified in recrudescing viremia following analytic treatment interruption. Proc Natl Acad Sci U S A. 2020 05 05; 117(18):9981-9990. PMID: 32300019.
    Citations: 9     Fields:    Translation:HumansCells
  43. Li JZ, Segal FP, Bosch RJ, Lalama CM, Roberts-Toler C, Delagreverie H, Getz R, Garcia-Broncano P, Kinslow J, Tressler R, Van Dam CN, Keefer M, Carrington M, Lichterfeld M, Kuritzkes D, Yu XG, Landay A, Sax PE. Antiretroviral Therapy Reduces T-cell Activation and Immune Exhaustion Markers in Human Immunodeficiency Virus Controllers. Clin Infect Dis. 2020 04 10; 70(8):1636-1642. PMID: 31131858.
    Citations: 7     Fields:    Translation:HumansCellsCTClinical Trials
  44. Ramirez JA, Maddali MV, Budak JZ, Li JZ, Lampiris H, Shah M. Evaluating the Concordance of Clinician Antiretroviral Prescribing Practices and HIV-ASSIST, an Online Clinical Decision Support Tool. J Gen Intern Med. 2020 05; 35(5):1498-1503. PMID: 31792870.
    Citations:    Fields:    
  45. Le CN, Britto P, Brummel SS, Hoffman RM, Li JZ, Flynn PM, Taha TE, Coletti A, Fowler MG, Bosch RJ, Gandhi RT, Klingman KL, McIntyre JA, Currier JS. Time to viral rebound and safety after antiretroviral treatment interruption in postpartum women compared with men. AIDS. 2019 11 15; 33(14):2149-2156. PMID: 31373919.
    Citations: 2     Fields:    Translation:HumansCells
  46. Maddali MV, Mehtani NJ, Converse C, Kapoor S, Pham P, Li JZ, Shah M. Development and Validation of HIV-ASSIST, an Online, Educational, Clinical Decision Support Tool to Guide Patient-Centered ARV Regimen Selection. . 2019 10 01; 82(2):188-194. PMID: 31513553.
    Citations: 2     Translation:Humans
  47. Jilg N, Li JZ. On the Road to a HIV Cure: Moving Beyond Berlin and London. Infect Dis Clin North Am. 2019 09; 33(3):857-868. PMID: 31395147.
    Citations: 2     Fields:    Translation:HumansCells
  48. Etemad B, Esmaeilzadeh E, Li JZ. Learning From the Exceptions: HIV Remission in Post-treatment Controllers. Front Immunol. 2019; 10:1749. PMID: 31396237.
    Citations: 4     Fields:    Translation:HumansCells
  49. Conway JM, Perelson AS, Li JZ. Predictions of time to HIV viral rebound following ART suspension that incorporate personal biomarkers. PLoS Comput Biol. 2019 07; 15(7):e1007229. PMID: 31339888.
    Citations: 7     Fields:    Translation:HumansCells
  50. Julg B, Dee L, Ananworanich J, Barouch DH, Bar K, Caskey M, Colby DJ, Dawson L, Dong KL, Dubé K, Eron J, Frater J, Gandhi RT, Geleziunas R, Goulder P, Hanna GJ, Jefferys R, Johnston R, Kuritzkes D, Li JZ, Likhitwonnawut U, van Lunzen J, Martinez-Picado J, Miller V, Montaner LJ, Nixon DF, Palm D, Pantaleo G, Peay H, Persaud D, Salzwedel J, Salzwedel K, Schacker T, Sheikh V, Søgaard OS, Spudich S, Stephenson K, Sugarman J, Taylor J, Tebas P, Tiemessen CT, Tressler R, Weiss CD, Zheng L, Robb ML, Michael NL, Mellors JW, Deeks SG, Walker BD. Recommendations for analytical antiretroviral treatment interruptions in HIV research trials-report of a consensus meeting. Lancet HIV. 2019 04; 6(4):e259-e268. PMID: 30885693.
    Citations: 43     Fields:    Translation:Humans
  51. Li JZ, Sax PE, Marconi VC, Fajnzylber J, Berzins B, Nyaku AN, Fichtenbaum CJ, Wilkin T, Benson CA, Koletar SL, Lorenzo-Redondo R, Taiwo BO. No Significant Changes to Residual Viremia After Switch to Dolutegravir and Lamivudine in a Randomized Trial. Open Forum Infect Dis. 2019 Mar; 6(3):ofz056. PMID: 30895201.
    Citations: 2     
  52. Einkauf KB, Lee GQ, Gao C, Sharaf R, Sun X, Hua S, Chen SM, Jiang C, Lian X, Chowdhury FZ, Rosenberg ES, Chun TW, Li JZ, Yu XG, Lichterfeld M. Intact HIV-1 proviruses accumulate at distinct chromosomal positions during prolonged antiretroviral therapy. J Clin Invest. 2019 03 01; 129(3):988-998. PMID: 30688658.
    Citations: 48     Fields:    Translation:HumansCellsCTClinical Trials
  53. Namazi G, Fajnzylber JM, Aga E, Bosch RJ, Acosta EP, Sharaf R, Hartogensis W, Jacobson JM, Connick E, Volberding P, Skiest D, Margolis D, Sneller MC, Little SJ, Gianella S, Smith DM, Kuritzkes DR, Gulick RM, Mellors JW, Mehraj V, Gandhi RT, Mitsuyasu R, Schooley RT, Henry K, Tebas P, Deeks SG, Chun TW, Collier AC, Routy JP, Hecht FM, Walker BD, Li JZ. The Control of HIV After Antiretroviral Medication Pause (CHAMP) Study: Posttreatment Controllers Identified From 14 Clinical Studies. J Infect Dis. 2018 11 05; 218(12):1954-1963. PMID: 30085241.
    Citations: 40     Fields:    Translation:HumansCells
  54. Wen Y, Bar KJ, Li JZ. Lessons learned from HIV antiretroviral treatment interruption trials. Curr Opin HIV AIDS. 2018 09; 13(5):416-421. PMID: 29878912.
    Citations: 13     Fields:    Translation:HumansCells
  55. Sharaf R, Lee GQ, Sun X, Etemad B, Aboukhater LM, Hu Z, Brumme ZL, Aga E, Bosch RJ, Wen Y, Namazi G, Gao C, Acosta EP, Gandhi RT, Jacobson JM, Skiest D, Margolis DM, Mitsuyasu R, Volberding P, Connick E, Kuritzkes DR, Lederman MM, Yu XG, Lichterfeld M, Li JZ. HIV-1 proviral landscapes distinguish posttreatment controllers from noncontrollers. J Clin Invest. 2018 08 31; 128(9):4074-4085. PMID: 30024859.
    Citations: 23     Fields:    Translation:HumansCells
  56. Salantes DB, Zheng Y, Mampe F, Srivastava T, Beg S, Lai J, Li JZ, Tressler RL, Koup RA, Hoxie J, Abdel-Mohsen M, Sherrill-Mix S, McCormick K, Overton ET, Bushman FD, Learn GH, Siliciano RF, Siliciano JM, Tebas P, Bar KJ. HIV-1 latent reservoir size and diversity are stable following brief treatment interruption. J Clin Invest. 2018 07 02; 128(7):3102-3115. PMID: 29911997.
    Citations: 33     Fields:    Translation:HumansCellsCTClinical Trials
  57. Strongin Z, Sharaf R, VanBelzen DJ, Jacobson JM, Connick E, Volberding P, Skiest DJ, Gandhi RT, Kuritzkes DR, O'Doherty U, Li JZ. Effect of Short-Term Antiretroviral Therapy Interruption on Levels of Integrated HIV DNA. J Virol. 2018 06 15; 92(12). PMID: 29593048.
    Citations: 12     Fields:    Translation:HumansCells
  58. Taiwo BO, Marconi VC, Berzins B, Moser CB, Nyaku AN, Fichtenbaum CJ, Benson CA, Wilkin T, Koletar SL, Colasanti J, Acosta EP, Li JZ, Sax PE. Dolutegravir Plus Lamivudine Maintains Human Immunodeficiency Virus-1 Suppression Through Week 48 in a Pilot Randomized Trial. Clin Infect Dis. 2018 05 17; 66(11):1794-1797. PMID: 29293895.
    Citations: 18     Fields:    Translation:HumansCells
  59. Stella-Ascariz N, Arribas JR, Paredes R, Li JZ. The Role of HIV-1 Drug-Resistant Minority Variants in Treatment Failure. J Infect Dis. 2017 12 01; 216(suppl_9):S847-S850. PMID: 29207001.
    Citations: 16     Fields:    Translation:HumansCells
  60. Park YJ, Etemad B, Ahmed H, Naranbhai V, Aga E, Bosch RJ, Mellors JW, Kuritzkes DR, Para M, Gandhi RT, Carrington M, Li JZ. Impact of HLA Class I Alleles on Timing of HIV Rebound After Antiretroviral Treatment Interruption. Pathog Immun. 2017; 2(3):431-445. PMID: 29333522.
    Citations: 2     
  61. Kanakasabapathy MK, Pandya HJ, Draz MS, Chug MK, Sadasivam M, Kumar S, Etemad B, Yogesh V, Safavieh M, Asghar W, Li JZ, Tsibris AM, Kuritzkes DR, Shafiee H. Rapid, label-free CD4 testing using a smartphone compatible device. Lab Chip. 2017 08 22; 17(17):2910-2919. PMID: 28702612.
    Citations: 15     Fields:    Translation:Humans
  62. Henrich TJ, Hobbs KS, Hanhauser E, Scully E, Hogan LE, Robles YP, Leadabrand KS, Marty FM, Palmer CD, Jost S, Körner C, Li JZ, Gandhi RT, Hamdan A, Abramson J, LaCasce AS, Kuritzkes DR. Human Immunodeficiency Virus Type 1 Persistence Following Systemic Chemotherapy for Malignancy. J Infect Dis. 2017 07 15; 216(2):254-262. PMID: 28838149.
    Citations: 19     Fields:    Translation:HumansCells
  63. Sharaf RR, Li JZ. The Alphabet Soup of HIV Reservoir Markers. Curr HIV/AIDS Rep. 2017 04; 14(2):72-81. PMID: 28401492.
    Citations: 10     Fields:    Translation:HumansAnimalsCells
  64. Jumare J, Sunshine S, Ahmed H, El-Kamary SS, Magder L, Hungerford L, Burdo T, Eyzaguirre LM, Umlauf A, Cherner M, Abimiku A, Charurat M, Li JZ, Blattner WA, Royal W. Peripheral blood lymphocyte HIV DNA levels correlate with HIV associated neurocognitive disorders in Nigeria. J Neurovirol. 2017 06; 23(3):474-482. PMID: 28243867.
    Citations: 4     Fields:    Translation:HumansCells
  65. Wen Y, Li JZ. Post-treatment HIV controllers or spontaneous controllers in disguise? AIDS. 2017 02 20; 31(4):587-589. PMID: 28118234.
    Citations: 3     Fields:    Translation:HumansCells
  66. Delagrèverie HM, Delaugerre C, Lewin SR, Deeks SG, Li JZ. Ongoing Clinical Trials of Human Immunodeficiency Virus Latency-Reversing and Immunomodulatory Agents. Open Forum Infect Dis. 2016 Oct; 3(4):ofw189. PMID: 27757411.
    Citations: 32     
  67. Treasure GC, Aga E, Bosch RJ, Mellors JW, Kuritzkes DR, Para M, Gandhi RT, Li JZ. Brief Report: Relationship Among Viral Load Outcomes in HIV Treatment Interruption Trials. . 2016 07 01; 72(3):310-3. PMID: 26910502.
    Citations: 7     Translation:HumansCells
  68. Tang JC, Drokhlyansky E, Etemad B, Rudolph S, Guo B, Wang S, Ellis EG, Li JZ, Cepko CL. Detection and manipulation of live antigen-expressing cells using conditionally stable nanobodies. Elife. 2016 05 20; 5. PMID: 27205882.
    Citations: 22     Fields:    Translation:HumansAnimalsCells
  69. Sunshine S, Kirchner R, Amr SS, Mansur L, Shakhbatyan R, Kim M, Bosque A, Siliciano RF, Planelles V, Hofmann O, Ho Sui S, Li JZ. HIV Integration Site Analysis of Cellular Models of HIV Latency with a Probe-Enriched Next-Generation Sequencing Assay. J Virol. 2016 May; 90(9):4511-4519. PMID: 26912621.
    Citations: 15     Fields:    Translation:HumansCells
  70. Li JZ, Etemad B, Ahmed H, Aga E, Bosch RJ, Mellors JW, Kuritzkes DR, Lederman MM, Para M, Gandhi RT. The size of the expressed HIV reservoir predicts timing of viral rebound after treatment interruption. AIDS. 2016 Jan 28; 30(3):343-53. PMID: 26588174.
    Citations: 101     Fields:    Translation:HumansCells
  71. Kearney MF, Wiegand A, Shao W, Coffin JM, Mellors JW, Lederman M, Gandhi RT, Keele BF, Li JZ. Origin of Rebound Plasma HIV Includes Cells with Identical Proviruses That Are Transcriptionally Active before Stopping of Antiretroviral Therapy. J Virol. 2016 02 01; 90(3):1369-76. PMID: 26581989.
    Citations: 55     Fields:    Translation:HumansCells
  72. Ndhlovu ZM, Stampouloglou E, Cesa K, Mavrothalassitis O, Alvino DM, Li JZ, Wilton S, Karel D, Piechocka-Trocha A, Chen H, Pereyra F, Walker BD. The Breadth of Expandable Memory CD8+ T Cells Inversely Correlates with Residual Viral Loads in HIV Elite Controllers. J Virol. 2015 Nov; 89(21):10735-47. PMID: 26269189.
    Citations: 18     Fields:    Translation:HumansCells
  73. Li JZ, Smith DM, Mellors JW. The need for treatment interruption studies and biomarker identification in the search for an HIV cure. AIDS. 2015 Jul 31; 29(12):1429-32. PMID: 25870989.
    Citations: 26     Fields:    Translation:Humans
  74. Konstantopoulos C, Ribaudo H, Ragland K, Bangsberg DR, Li JZ. Antiretroviral regimen and suboptimal medication adherence are associated with low-level human immunodeficiency virus viremia. Open Forum Infect Dis. 2015 Jan; 2(1):ofu119. PMID: 25884007.
    Citations: 9     
  75. Li JZ, Arnold KB, Lo J, Dugast AS, Plants J, Ribaudo HJ, Cesa K, Heisey A, Kuritzkes DR, Lauffenburger DA, Alter G, Landay A, Grinspoon S, Pereyra F. Differential levels of soluble inflammatory markers by human immunodeficiency virus controller status and demographics. Open Forum Infect Dis. 2015 Jan; 2(1):ofu117. PMID: 25884005.
    Citations: 24     
  76. Li JZ, Heisey A, Ahmed H, Wang H, Zheng L, Carrington M, Wrin T, Schooley RT, Lederman MM, Kuritzkes DR. Relationship of HIV reservoir characteristics with immune status and viral rebound kinetics in an HIV therapeutic vaccine study. AIDS. 2014 Nov 28; 28(18):2649-57. PMID: 25254301.
    Citations: 18     Fields:    Translation:HumansCells
  77. Henrich TJ, Hanhauser E, Marty FM, Sirignano MN, Keating S, Lee TH, Robles YP, Davis BT, Li JZ, Heisey A, Hill AL, Busch MP, Armand P, Soiffer RJ, Altfeld M, Kuritzkes DR. Antiretroviral-free HIV-1 remission and viral rebound after allogeneic stem cell transplantation: report of 2 cases. Ann Intern Med. 2014 Sep 02; 161(5):319-27. PMID: 25047577.
    Citations: 194     Fields:    Translation:HumansCells
  78. Buzon MJ, Martin-Gayo E, Pereyra F, Ouyang Z, Sun H, Li JZ, Piovoso M, Shaw A, Dalmau J, Zangger N, Martinez-Picado J, Zurakowski R, Yu XG, Telenti A, Walker BD, Rosenberg ES, Lichterfeld M. Long-term antiretroviral treatment initiated at primary HIV-1 infection affects the size, composition, and decay kinetics of the reservoir of HIV-1-infected CD4 T cells. J Virol. 2014 Sep 01; 88(17):10056-65. PMID: 24965451.
    Citations: 112     Fields:    Translation:HumansCells
  79. Al-Hajjar SH, Frayha HH, Al-Hazmi M, Batawi R, McIntosh K, Sax PE, Al-Thawadi S, Al-Jumaah S, Busch MP, Hanhauser E, Kuritzkes DR, Li JZ, Henrich TJ. Prevention of HIV-1 transmission with postexposure prophylaxis after inadvertent infected blood transfusion. AIDS. 2014 Jun 19; 28(10):1539-41. PMID: 24896805.
    Citations: 1     Fields:    Translation:HumansCells
  80. Li JZ, Gandhi RT. The sooner, the better: more evidence that early antiretroviral therapy lowers viral reservoirs in HIV-infected infants. J Infect Dis. 2014 Nov 15; 210(10):1519-22. PMID: 24850791.
    Citations: 2     Fields:    Translation:HumansCellsPHPublic Health
  81. Swenson LC, Min JE, Woods CK, Cai E, Li JZ, Montaner JS, Harrigan PR, Gonzalez-Serna A. HIV drug resistance detected during low-level viraemia is associated with subsequent virologic failure. AIDS. 2014 May 15; 28(8):1125-34. PMID: 24451160.
    Citations: 16     Fields:    Translation:HumansCells
  82. Ryscavage P, Kelly S, Li JZ, Harrigan PR, Taiwo B. Significance and clinical management of persistent low-level viremia and very-low-level viremia in HIV-1-infected patients. Antimicrob Agents Chemother. 2014 Jul; 58(7):3585-98. PMID: 24733471.
    Citations: 25     Fields:    Translation:HumansCells
  83. Li JZ, Chapman B, Charlebois P, Hofmann O, Weiner B, Porter AJ, Samuel R, Vardhanabhuti S, Zheng L, Eron J, Taiwo B, Zody MC, Henn MR, Kuritzkes DR, Hide W, Wilson CC, Berzins BI, Acosta EP, Bastow B, Kim PS, Read SW, Janik J, Meres DS, Lederman MM, Mong-Kryspin L, Shaw KE, Zimmerman LG, Leavitt R, De La Rosa G, Jennings A. Comparison of illumina and 454 deep sequencing in participants failing raltegravir-based antiretroviral therapy. PLoS One. 2014; 9(3):e90485. PMID: 24603872.
    Citations: 11     Fields:    Translation:HumansCellsCTClinical Trials
  84. Li JZ, Gallien S, Ribaudo H, Heisey A, Bangsberg DR, Kuritzkes DR. Incomplete adherence to antiretroviral therapy is associated with higher levels of residual HIV-1 viremia. AIDS. 2014 Jan 14; 28(2):181-186. PMID: 24361679.
    Citations: 34     Fields:    Translation:HumansCells
  85. Buzon MJ, Sun H, Li C, Shaw A, Seiss K, Ouyang Z, Martin-Gayo E, Leng J, Henrich TJ, Li JZ, Pereyra F, Zurakowski R, Walker BD, Rosenberg ES, Yu XG, Lichterfeld M. HIV-1 persistence in CD4+ T cells with stem cell-like properties. Nat Med. 2014 Feb; 20(2):139-42. PMID: 24412925.
    Citations: 188     Fields:    Translation:HumansCells
  86. Li JZ. HIV-1 drug-resistant minority variants: sweating the small stuff. J Infect Dis. 2014 Mar 01; 209(5):639-41. PMID: 24273184.
    Citations: 5     Fields:    Translation:HumansCells
  87. Henrich TJ, Hu Z, Li JZ, Sciaranghella G, Busch MP, Keating SM, Gallien S, Lin NH, Giguel FF, Lavoie L, Ho VT, Armand P, Soiffer RJ, Sagar M, Lacasce AS, Kuritzkes DR. Long-term reduction in peripheral blood HIV type 1 reservoirs following reduced-intensity conditioning allogeneic stem cell transplantation. J Infect Dis. 2013 Jun 01; 207(11):1694-702. PMID: 23460751.
    Citations: 134     Fields:    Translation:HumansCells
  88. Li JZ, Kuritzkes DR. Clinical implications of HIV-1 minority variants. Clin Infect Dis. 2013 Jun; 56(11):1667-74. PMID: 23446628.
    Citations: 25     Fields:    Translation:HumansCells
  89. Huang J, Jiang J, Li JZ, Yang X, Deng W, Abdullah AS, Qin B, Upur H, Zhong C, Wang Q, Wang Q, Ruan Y, Zou Y, Ye L, Xie P, Wei F, Xu N, Wei B, Liang H. Prevalence and correlates of sexual risk behaviors among drug users in western China: implications for HIV transmission. AIDS Res Hum Retroviruses. 2013 Apr; 29(4):673-80. PMID: 23210514.
    Citations: 5     Fields:    Translation:Humans
  90. Li JZ, Paredes R, Ribaudo HJ, Kozal MJ, Svarovskaia ES, Johnson JA, Geretti AM, Metzner KJ, Jakobsen MR, Hullsiek KH, Ostergaard L, Miller MD, Kuritzkes DR. Impact of minority nonnucleoside reverse transcriptase inhibitor resistance mutations on resistance genotype after virologic failure. J Infect Dis. 2013 Mar 15; 207(6):893-7. PMID: 23264671.
    Citations: 24     Fields:    Translation:HumansCells
  91. Henrich TJ, Gallien S, Li JZ, Pereyra F, Kuritzkes DR. Low-level detection and quantitation of cellular HIV-1 DNA and 2-LTR circles using droplet digital PCR. J Virol Methods. 2012 Dec; 186(1-2):68-72. PMID: 22974526.
    Citations: 56     Fields:    Translation:HumansCells
  92. Li JZ, Christensen JA, Wang H, Spritzler J, Kuritzkes DR. Evaluation of HIV-1 ambiguous nucleotide frequency during antiretroviral treatment interruption. . 2012 Sep 01; 61(1):19-22. PMID: 22732468.
    Citations: 1     Translation:HumansCells
  93. Li JZ, Gallien S, Do TD, Martin JN, Deeks S, Kuritzkes DR, Hatano H. Prevalence and significance of HIV-1 drug resistance mutations among patients on antiretroviral therapy with detectable low-level viremia. Antimicrob Agents Chemother. 2012 Nov; 56(11):5998-6000. PMID: 22890763.
    Citations: 18     Fields:    Translation:HumansCells
  94. Li JZ, Brumme CJ, Lederman MM, Brumme ZL, Wang H, Spritzler J, Carrington M, Medvik K, Walker BD, Schooley RT, Kuritzkes DR. Characteristics and outcomes of initial virologic suppressors during analytic treatment interruption in a therapeutic HIV-1 gag vaccine trial. PLoS One. 2012; 7(3):e34134. PMID: 22479542.
    Citations: 4     Fields:    Translation:HumansCells
  95. Li JZ, Paredes R, Ribaudo HJ, Svarovskaia ES, Kozal MJ, Hullsiek KH, Miller MD, Bangsberg DR, Kuritzkes DR. Relationship between minority nonnucleoside reverse transcriptase inhibitor resistance mutations, adherence, and the risk of virologic failure. AIDS. 2012 Jan 14; 26(2):185-92. PMID: 22179227.
    Citations: 42     Fields:    Translation:HumansCells
  96. Chew KW, Yen IH, Li JZ, Winston LG. Predictors of pneumonia severity in HIV-infected adults admitted to an Urban public hospital. AIDS Patient Care STDS. 2011 May; 25(5):273-7. PMID: 21488749.
    Citations: 8     Fields:    Translation:Humans
  97. Li JZ, Paredes R, Ribaudo HJ, Svarovskaia ES, Metzner KJ, Kozal MJ, Hullsiek KH, Balduin M, Jakobsen MR, Geretti AM, Thiebaut R, Ostergaard L, Masquelier B, Johnson JA, Miller MD, Kuritzkes DR. Low-frequency HIV-1 drug resistance mutations and risk of NNRTI-based antiretroviral treatment failure: a systematic review and pooled analysis. JAMA. 2011 Apr 06; 305(13):1327-35. PMID: 21467286.
    Citations: 146     Fields:    Translation:HumansCells
  98. Li JZ, Brumme ZL, Brumme CJ, Wang H, Spritzler J, Robertson MN, Lederman MM, Carrington M, Walker BD, Schooley RT, Kuritzkes DR. Factors associated with viral rebound in HIV-1-infected individuals enrolled in a therapeutic HIV-1 gag vaccine trial. J Infect Dis. 2011 Apr 01; 203(7):976-83. PMID: 21402549.
    Citations: 13     Fields:    Translation:HumansCellsPHPublic Health
  99. Henrich TJ, Li JZ, Felsenstein D, Kotton CN, Plenge RM, Pereyra F, Marty FM, Lin NH, Grazioso P, Crochiere DM, Eggers D, Kuritzkes DR, Tsibris AM. Xenotropic murine leukemia virus-related virus prevalence in patients with chronic fatigue syndrome or chronic immunomodulatory conditions. J Infect Dis. 2010 Nov 15; 202(10):1478-81. PMID: 20936980.
    Citations: 36     Fields:    Translation:HumansCells
  100. Tucker JD, Li JZ, Robbins GK, Davis BT, Lobo AM, Kunkel J, Papaliodis GN, Durand ML, Felsenstein D. Ocular syphilis among HIV-infected patients: a systematic analysis of the literature. Sex Transm Infect. 2011 Feb; 87(1):4-8. PMID: 20798396.
    Citations: 25     Fields:    Translation:HumansCells
  101. Li JZ, Tucker JD, Lobo AM, Marra CM, Davis BT, Papaliodis GN, Felsenstein D, Durand ML, Yawetz S, Robbins GK. Ocular syphilis among HIV-infected individuals. Clin Infect Dis. 2010 Aug 15; 51(4):468-71. PMID: 20604717.
    Citations: 12     Fields:    Translation:Humans
  102. Li JZ, Sax PE. AZT or tenofovir for patients with the K65R mutation? J Watch AIDS Clin Care. 2010 Jun; 22(6):51-2. PMID: 20648965.
    Citations:    Fields:    Translation:HumansCells
  103. Li JZ, Sax PE. HSV-1 encephalitis complicated by cerebral hemorrhage in an HIV-positive person. AIDS Read. 2009 Apr; 19(4):153-5. PMID: 19388182.
    Citations: 6     Fields:    Translation:HumansCells
  104. Li JZ, Huen W. Images in clinical medicine. Calciphylaxis with arterial calcification. N Engl J Med. 2007 Sep 27; 357(13):1326. PMID: 17898102.
    Citations: 2     Fields:    Translation:Humans
  105. Li JZ, Winston LG, Moore DH, Bent S. Efficacy of short-course antibiotic regimens for community-acquired pneumonia: a meta-analysis. Am J Med. 2007 Sep; 120(9):783-90. PMID: 17765048.
    Citations: 26     Fields:    Translation:Humans
  106. Li JZ, Mack EC, Levy JA. Virucidal efficacy of soap and water against human immunodeficiency virus in genital secretions. Antimicrob Agents Chemother. 2003 Oct; 47(10):3321-2. PMID: 14506048.
    Citations: 2     Fields:    Translation:HumansCells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.