Harvard Catalyst Profiles

Contact, publication, and social network information about Harvard faculty and fellows.

James Francis Riordan, Ph.D.


The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. R01HL034704 (RIORDAN, JAMES F.) Sep 1, 1985 - Dec 31, 1996
    Role: Principal Investigator

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Acharya KR, Sturrock ED, Riordan JF, Ehlers MR. Ace revisited: a new target for structure-based drug design. Nat Rev Drug Discov. 2003 Nov; 2(11):891-902. PMID: 14668810.
    Citations: 72     Fields:    Translation:HumansCells
  2. Riordan JF. Angiotensin-I-converting enzyme and its relatives. Genome Biol. 2003; 4(8):225. PMID: 12914653; PMCID: PMC193637.
    Citations: 87     Fields:    Translation:HumansAnimals
  3. Xu ZP, Tsuji T, Riordan JF, Hu GF. Identification and characterization of an angiogenin-binding DNA sequence that stimulates luciferase reporter gene expression. Biochemistry. 2003 Jan 14; 42(1):121-8. PMID: 12515546.
    Citations: 54     Fields:    Translation:HumansCells
  4. Xu ZP, Tsuji T, Riordan JF, Hu GF. The nuclear function of angiogenin in endothelial cells is related to rRNA production. Biochem Biophys Res Commun. 2002 Jun 07; 294(2):287-92. PMID: 12051708.
    Citations: 54     Fields:    Translation:Cells
  5. Liu S, Yu D, Xu ZP, Riordan JF, Hu GF. Angiogenin activates Erk1/2 in human umbilical vein endothelial cells. Biochem Biophys Res Commun. 2001 Sep 14; 287(1):305-10. PMID: 11549292.
    Citations: 31     Fields:    Translation:HumansCells
  6. Riordan JF, Shapiro R. Isolation and enzymatic activity of angiogenin. Methods Mol Biol. 2001; 160:375-85. PMID: 11265298.
    Citations: 2     Fields:    Translation:HumansAnimals
  7. Riordan JF. Angiogenin. Methods Enzymol. 2001; 341:263-73. PMID: 11582782.
    Citations: 18     Fields:    Translation:HumansAnimalsCells
  8. Hu Gf, Kim Hj, Xu Cj, Riordan JF. Fibroblast growth factors are translocated to the nucleus of human endothelial cells in a microtubule- and lysosome-independent pathway. Biochem Biophys Res Commun. 2000 Jul 05; 273(2):551-6. PMID: 10873643.
    Citations: 2     Fields:    Translation:HumansCells
  9. Hu Gf, Xu Cj, Riordan JF. Human angiogenin is rapidly translocated to the nucleus of human umbilical vein endothelial cells and binds to DNA. J Cell Biochem. 2000 Jan; 76(3):452-62. PMID: 10649442.
    Citations: 34     Fields:    Translation:HumansCells
  10. Schwager SL, Chubb AJ, Scholle RR, Brandt WF, Mentele R, Riordan JF, Sturrock ED, Ehlers MR. Modulation of juxtamembrane cleavage ("shedding") of angiotensin-converting enzyme by stalk glycosylation: evidence for an alternative shedding protease. Biochemistry. 1999 Aug 10; 38(32):10388-97. PMID: 10441133.
    Citations: 8     Fields:    Translation:HumansAnimalsCells
  11. Nobile V, Russo N, Hu Gf, Riordan JF. Inhibition of human angiogenin by DNA aptamers: nuclear colocalization of an angiogenin-inhibitor complex. Biochemistry. 1998 May 12; 37(19):6857-63. PMID: 9578572.
    Citations: 7     Fields:    Translation:HumansCells
  12. Vallee BL, Riordan JF. Organogenesis and angiogenin. Cell Mol Life Sci. 1997 Oct; 53(10):803-15. PMID: 9413551.
    Citations: 9     Fields:    Translation:HumansAnimalsCells
  13. Li R, Riordan JF, Hu G. Nuclear translocation of human angiogenin in cultured human umbilical artery endothelial cells is microtubule and lysosome independent. Biochem Biophys Res Commun. 1997 Sep 18; 238(2):305-12. PMID: 9299500.
    Citations: 15     Fields:    Translation:HumansCells
  14. Sturrock ED, Danilov SM, Riordan JF. Limited proteolysis of human kidney angiotensin-converting enzyme and generation of catalytically active N- and C-terminal domains. Biochem Biophys Res Commun. 1997 Jul 09; 236(1):16-9. PMID: 9223417.
    Citations: 6     Fields:    Translation:HumansCells
  15. Ehlers MR, Schwager SL, Chubb AJ, Scholle RR, Brandt WF, Riordan JF. Proteolytic release of membrane proteins: studies on a membrane-protein-solubilizing activity in CHO cells. Immunopharmacology. 1997 Jun; 36(2-3):271-8. PMID: 9228557.
    Citations:    Fields:    Translation:HumansAnimalsCells
  16. Hu GF, Riordan JF, Vallee BL. A putative angiogenin receptor in angiogenin-responsive human endothelial cells. Proc Natl Acad Sci U S A. 1997 Mar 18; 94(6):2204-9. PMID: 9122172; PMCID: PMC20065.
    Citations: 54     Fields:    Translation:Humans
  17. Yu XC, Sturrock ED, Wu Z, Biemann K, Ehlers MR, Riordan JF. Identification of N-linked glycosylation sites in human testis angiotensin-converting enzyme and expression of an active deglycosylated form. J Biol Chem. 1997 Feb 07; 272(6):3511-9. PMID: 9013598.
    Citations: 18     Fields:    Translation:HumansAnimalsCells
  18. Sturrock ED, Yu XC, Wu Z, Biemann K, Riordan JF. Assignment of free and disulfide-bonded cysteine residues in testis angiotensin-converting enzyme: functional implications. Biochemistry. 1996 Jul 23; 35(29):9560-6. PMID: 8755737.
    Citations: 3     Fields:    Translation:HumansCells
  19. Ehlers MR, Schwager SL, Scholle RR, Manji GA, Brandt WF, Riordan JF. Proteolytic release of membrane-bound angiotensin-converting enzyme: role of the juxtamembrane stalk sequence. Biochemistry. 1996 Jul 23; 35(29):9549-59. PMID: 8755736.
    Citations: 22     Fields:    Translation:AnimalsCells
  20. Russo N, Nobile V, Di Donato A, Riordan JF, Vallee BL. The C-terminal region of human angiogenin has a dual role in enzymatic activity. Proc Natl Acad Sci U S A. 1996 Apr 16; 93(8):3243-7. PMID: 8622921; PMCID: PMC39590.
    Citations: 7     Fields:    Translation:HumansCells
  21. Riordan JF. Angiotensin II: biosynthesis, molecular recognition, and signal transduction. Cell Mol Neurobiol. 1995 Dec; 15(6):637-51. PMID: 8719034.
    Citations: 1     Fields:    Translation:HumansAnimalsCells
  22. Shapiro R, Riordan JF, Vallee BL. LRRning the RIte of springs. Nat Struct Biol. 1995 May; 2(5):350-4. PMID: 7664088.
    Citations: 4     Fields:    Translation:HumansAnimalsCells
  23. Acharya KR, Shapiro R, Riordan JF, Vallee BL. Crystal structure of bovine angiogenin at 1.5-A resolution. Proc Natl Acad Sci U S A. 1995 Mar 28; 92(7):2949-53. PMID: 7708754; PMCID: PMC42336.
    Citations: 12     Fields:    Translation:HumansAnimalsCells
  24. Ehlers MR, Scholle RR, Riordan JF. Proteolytic release of human angiotensin-converting enzyme expressed in Chinese hamster ovary cells is enhanced by phorbol ester. Biochem Biophys Res Commun. 1995 Jan 17; 206(2):541-7. PMID: 7826370.
    Citations: 3     Fields:    Translation:HumansAnimalsCells
  25. Coker RJ, Desmond N, Poznansky M, Smith C, Shafi MS, Bell D, Riordan JF, Murphy S. Experience of HIV disease in a London District General Hospital. Int J STD AIDS. 1995 Jan-Feb; 6(1):47-9. PMID: 7727583.
    Citations: 1     Fields:    Translation:Humans
  26. Hu G, Riordan JF, Vallee BL. Angiogenin promotes invasiveness of cultured endothelial cells by stimulation of cell-associated proteolytic activities. Proc Natl Acad Sci U S A. 1994 Dec 06; 91(25):12096-100. PMID: 7991590; PMCID: PMC45383.
    Citations: 46     Fields:    Translation:AnimalsCells
  27. Moroianu J, Riordan JF. Nuclear translocation of angiogenic proteins in endothelial cells: an essential step in angiogenesis. Biochemistry. 1994 Oct 25; 33(42):12535-9. PMID: 7522560.
    Citations: 7     Fields:    Translation:HumansAnimalsCells
  28. Moroianu J, Riordan JF. Identification of the nucleolar targeting signal of human angiogenin. Biochem Biophys Res Commun. 1994 Sep 30; 203(3):1765-72. PMID: 7945327.
    Citations: 43     Fields:    Translation:HumansAnimalsCells
  29. Acharya KR, Shapiro R, Allen SC, Riordan JF, Vallee BL. Crystal structure of human angiogenin reveals the structural basis for its functional divergence from ribonuclease. Proc Natl Acad Sci U S A. 1994 Apr 12; 91(8):2915-9. PMID: 8159679; PMCID: PMC43485.
    Citations: 49     Fields:    Translation:HumansCells
  30. Russo N, Shapiro R, Acharya KR, Riordan JF, Vallee BL. Role of glutamine-117 in the ribonucleolytic activity of human angiogenin. Proc Natl Acad Sci U S A. 1994 Apr 12; 91(8):2920-4. PMID: 8159680; PMCID: PMC43486.
    Citations: 36     Fields:    Translation:HumansCells
  31. Moroianu J, Riordan JF. Nuclear translocation of angiogenin in proliferating endothelial cells is essential to its angiogenic activity. Proc Natl Acad Sci U S A. 1994 Mar 01; 91(5):1677-81. PMID: 8127865; PMCID: PMC43226.
    Citations: 104     Fields:    Translation:HumansAnimalsCells
  32. Riordan JF. Angiotensin converting enzyme inhibitors and alcohol abuse. EXS. 1994; 71:323-31. PMID: 8032163.
    Citations: 1     Fields:    Translation:HumansAnimalsCells
  33. Hu GF, Riordan JF. Angiogenin enhances actin acceleration of plasminogen activation. Biochem Biophys Res Commun. 1993 Dec 15; 197(2):682-7. PMID: 8267604.
    Citations: 23     Fields:    Translation:Animals
  34. Curran TP, Shapiro R, Riordan JF, Vallee BL. Modulation of the activity of angiogenin by mutagenesis at Asp-116. Biochim Biophys Acta. 1993 Oct 06; 1202(2):281-6. PMID: 7691185.
    Citations: 8     Fields:    Translation:HumansAnimalsCells
  35. Moroianu J, Fett JW, Riordan JF, Vallee BL. Actin is a surface component of calf pulmonary artery endothelial cells in culture. Proc Natl Acad Sci U S A. 1993 May 01; 90(9):3815-9. PMID: 8483899; PMCID: PMC46396.
    Citations: 18     Fields:    Translation:AnimalsCells
  36. Curran TP, Shapiro R, Riordan JF. Alteration of the enzymatic specificity of human angiogenin by site-directed mutagenesis. Biochemistry. 1993 Mar 09; 32(9):2307-13. PMID: 8095159.
    Citations: 25     Fields:    Translation:HumansAnimalsCells
  37. Hu GF, Strydom DJ, Fett JW, Riordan JF, Vallee BL. Actin is a binding protein for angiogenin. Proc Natl Acad Sci U S A. 1993 Feb 15; 90(4):1217-21. PMID: 7679494; PMCID: PMC45843.
    Citations: 42     Fields:    Translation:HumansAnimalsCells
  38. Acharya KR, Subramanian V, Shapiro R, Riordan JF, Vallee BL. Crystallization and preliminary X-ray analysis of human angiogenin. J Mol Biol. 1992 Dec 20; 228(4):1269-70. PMID: 1474591.
    Citations: 3     Fields:    Translation:HumansCells
  39. Chen YN, Ehlers MR, Riordan JF. The functional role of tyrosine-200 in human testis angiotensin-converting enzyme. Biochem Biophys Res Commun. 1992 Apr 15; 184(1):306-9. PMID: 1314588.
    Citations:    Fields:    Translation:HumansAnimalsCells
  40. Ehlers MR, Chen YN, Riordan JF. The unique N-terminal sequence of testis angiotensin-converting enzyme is heavily O-glycosylated and unessential for activity or stability. Biochem Biophys Res Commun. 1992 Feb 28; 183(1):199-205. PMID: 1311921.
    Citations: 12     Fields:    Translation:HumansAnimalsCells
  41. Ehlers MR, Riordan JF. Membrane proteins with soluble counterparts: role of proteolysis in the release of transmembrane proteins. Biochemistry. 1991 Oct 22; 30(42):10065-74. PMID: 1931937.
    Citations: 83     Fields:    Translation:AnimalsCells
  42. Ehlers MR, Riordan JF. Angiotensin-converting enzyme: zinc- and inhibitor-binding stoichiometries of the somatic and testis isozymes. Biochemistry. 1991 Jul 23; 30(29):7118-26. PMID: 1649623.
    Citations: 29     Fields:    Translation:HumansAnimalsCells
  43. Hu GF, Chang SI, Riordan JF, Vallee BL. An angiogenin-binding protein from endothelial cells. Proc Natl Acad Sci U S A. 1991 Mar 15; 88(6):2227-31. PMID: 2006162; PMCID: PMC51203.
    Citations: 30     Fields:    Translation:AnimalsCells
  44. Ehlers MR, Chen YN, Riordan JF. Spontaneous solubilization of membrane-bound human testis angiotensin-converting enzyme expressed in Chinese hamster ovary cells. Proc Natl Acad Sci U S A. 1991 Feb 01; 88(3):1009-13. PMID: 1846959; PMCID: PMC50944.
    Citations: 21     Fields:    Translation:HumansAnimalsCells
  45. Ehlers MR, Chen YN, Riordan JF. Purification and characterization of recombinant human testis angiotensin-converting enzyme expressed in Chinese hamster ovary cells. Protein Expr Purif. 1991 Feb; 2(1):1-9. PMID: 1668266.
    Citations: 8     Fields:    Translation:HumansAnimalsCells
  46. Riordan JF, Chen YN, Kleemann SG, Bünning P. Peptide inhibitors and the active site(s) of angiotensin converting enzyme. Biomed Biochim Acta. 1991; 50(4-6):809-14. PMID: 1666286.
    Citations:    Fields:    Translation:HumansAnimalsCells
  47. Chen YN, Riordan JF. Identification of essential tyrosine and lysine residues in angiotensin converting enzyme: evidence for a single active site. Biochemistry. 1990 Nov 20; 29(46):10493-8. PMID: 2176870.
    Citations: 5     Fields:    Translation:AnimalsCells
  48. Bünning P, Kleemann SG, Riordan JF. Essential residues in angiotensin converting enzyme: modification with 1-fluoro-2,4-dinitrobenzene. Biochemistry. 1990 Nov 20; 29(46):10488-92. PMID: 2176869.
    Citations: 1     Fields:    Translation:AnimalsCells
  49. Solomon BM, Larsen KS, Riordan JF. Catalytic and conformational changes induced by limited subtilisin cleavage of bovine carboxypeptidase A. Biochemistry. 1990 Aug 07; 29(31):7303-9. PMID: 1698455.
    Citations:    Fields:    Translation:AnimalsCells
  50. Moore F, Riordan JF. Angiogenin activates phospholipase C and elicits a rapid incorporation of fatty acid into cholesterol esters in vascular smooth muscle cells. Biochemistry. 1990 Jan 09; 29(1):228-33. PMID: 2322543.
    Citations: 7     Fields:    Translation:AnimalsCells
  51. Solomon B, Larsen K, Riordan JF. A neoisoform of carboxypeptidase A produced by a single proteolytic cleavage. Ann N Y Acad Sci. 1990; 613:594-9. PMID: 2076008.
    Citations:    Fields:    Translation:AnimalsCells
  52. Strydom DJ, Fett JW, Riordan JF. The odyssey of angiogenin: a protein that induces blood vessel growth. Anal Chem. 1989 Oct 15; 61(20):1173A-1179A. PMID: 2480723.
    Citations: 1     Fields:    Translation:AnimalsCells
  53. Ehlers MR, Fox EA, Strydom DJ, Riordan JF. Molecular cloning of human testicular angiotensin-converting enzyme: the testis isozyme is identical to the C-terminal half of endothelial angiotensin-converting enzyme. Proc Natl Acad Sci U S A. 1989 Oct; 86(20):7741-5. PMID: 2554286; PMCID: PMC298146.
    Citations: 59     Fields:    Translation:HumansCells
  54. Ehlers MR, Riordan JF. Angiotensin-converting enzyme: new concepts concerning its biological role. Biochemistry. 1989 Jun 27; 28(13):5311-8. PMID: 2476171.
    Citations: 81     Fields:    Translation:HumansAnimalsCells
  55. Martin MT, Holmquist B, Riordan JF. Effects of mechanism-based reversible inhibitors on the metal environment of cobalt(II)carboxypeptidase A: an electronic spectral study. J Inorg Biochem. 1989 May; 36(1):27-37. PMID: 2746219.
    Citations:    Fields:    Translation:Cells
  56. Martin MT, Holmquist B, Riordan JF. An angiotensin converting enzyme inhibitor is a tight-binding slow substrate of carboxypeptidase A. J Inorg Biochem. 1989 May; 36(1):39-50. PMID: 2746220.
    Citations: 4     Fields:    Translation:Cells
  57. Shapiro R, Fox EA, Riordan JF. Role of lysines in human angiogenin: chemical modification and site-directed mutagenesis. Biochemistry. 1989 Feb 21; 28(4):1726-32. PMID: 2497770.
    Citations: 48     Fields:    Translation:HumansCells
  58. Bertini I, Luchinat C, Messori L, Monnanni R, Auld DS, Riordan JF. 1H NMR spectroscopic characterization of binary and ternary complexes of cobalt(II) carboxypeptidase A with inhibitors. Biochemistry. 1988 Nov 01; 27(22):8318-25. PMID: 3242589.
    Citations: 2     Fields:    Translation:AnimalsCells
  59. St Clair DK, Rybak SM, Riordan JF, Vallee BL. Angiogenin abolishes cell-free protein synthesis by specific ribonucleolytic inactivation of 40S ribosomes. Biochemistry. 1988 Sep 20; 27(19):7263-8. PMID: 3207674.
    Citations: 9     Fields:    Translation:HumansAnimalsCells
  60. Kurachi K, Rybak SM, Fett JW, Shapiro R, Strydom DJ, Olson KA, Riordan JF, Davie EW, Vallee BL. Expression of human angiogenin in cultured baby hamster kidney cells. Biochemistry. 1988 Aug 23; 27(17):6557-62. PMID: 3219353.
    Citations: 4     Fields:    Translation:HumansAnimalsCells
  61. Riordan JF, Vallee BL. Human angiogenin, an organogenic protein. Br J Cancer. 1988 Jun; 57(6):587-90. PMID: 2457389; PMCID: PMC2246469.
    Citations: 3     Fields:    Translation:HumansAnimalsCells
  62. Halperin JA, Riordan JF, Tosteson DC. Characteristics of an inhibitor of the Na+/K+ pump in human cerebrospinal fluid. J Biol Chem. 1988 Jan 15; 263(2):646-51. PMID: 2826458.
    Citations: 4     Fields:    Translation:HumansCells
  63. Harper JW, Auld DS, Riordan JF, Vallee BL. Enzymatically active angiogenin/ribonuclease A hybrids formed by peptide interchange. Biochemistry. 1988 Jan 12; 27(1):219-26. PMID: 3349027.
    Citations: 4     Fields:    Translation:HumansCells
  64. Vallee BL, Riordan JF. Chemical and biochemical properties of human angiogenin. Adv Exp Med Biol. 1988; 234:41-53. PMID: 3063088.
    Citations: 3     Fields:    Translation:HumansAnimalsCells
  65. Riordan JF, Vallee BL. Preparation of metal-free water. Methods Enzymol. 1988; 158:3-6. PMID: 3374380.
    Citations: 3     Fields:    
  66. Shapiro R, Weremowicz S, Riordan JF, Vallee BL. Ribonucleolytic activity of angiogenin: essential histidine, lysine, and arginine residues. Proc Natl Acad Sci U S A. 1987 Dec; 84(24):8783-7. PMID: 3122207; PMCID: PMC299634.
    Citations: 27     Fields:    Translation:HumansCells
  67. St Clair DK, Rybak SM, Riordan JF, Vallee BL. Angiogenin abolishes cell-free protein synthesis by specific ribonucleolytic inactivation of ribosomes. Proc Natl Acad Sci U S A. 1987 Dec; 84(23):8330-4. PMID: 3479795; PMCID: PMC299536.
    Citations: 23     Fields:    Translation:HumansCells
  68. Bicknell R, Holmquist B, Lee FS, Martin MT, Riordan JF. Electronic spectroscopy of cobalt angiotensin converting enzyme and its inhibitor complexes. Biochemistry. 1987 Nov 17; 26(23):7291-7. PMID: 2827750.
    Citations: 2     Fields:    Translation:AnimalsCells
  69. Bünning P, Riordan JF. Sulfate potentiation of the chloride activation of angiotensin converting enzyme. Biochemistry. 1987 Jun 16; 26(12):3374-7. PMID: 2820467.
    Citations:    Fields:    Translation:AnimalsCells
  70. Harper JW, Shapiro R, Riordan JF. Observation of a chloride-dependent intermediate during catalysis by angiotensin converting enzyme using radiationless energy transfer. Biochemistry. 1987 Mar 10; 26(5):1284-8. PMID: 3032249.
    Citations:    Fields:    Translation:AnimalsCells
  71. Martin M, Vallee BL, Riordan JF. Fluorescent inhibitor probes of enzyme active site conformation: anion binding to angiotensin-converting enzyme. Anal Biochem. 1987 Mar; 161(2):341-7. PMID: 3034100.
    Citations:    Fields:    Translation:Cells
  72. Shapiro R, Riordan JF, Vallee BL. Characteristic ribonucleolytic activity of human angiogenin. Biochemistry. 1986 Jun 17; 25(12):3527-32. PMID: 2424496.
    Citations: 96     Fields:    Translation:HumansCells
  73. Palmer KA, Scheraga HA, Riordan JF, Vallee BL. A preliminary three-dimensional structure of angiogenin. Proc Natl Acad Sci U S A. 1986 Apr; 83(7):1965-9. PMID: 3457369; PMCID: PMC323210.
    Citations: 17     Fields:    Translation:HumansCells
  74. Kleemann SG, Keung WM, Riordan JF. Metal binding to angiotensin converting enzyme: implications for the metal binding site. J Inorg Biochem. 1986 Feb; 26(2):93-106. PMID: 3007669.
    Citations: 1     Fields:    Translation:Cells
  75. Riordan JF, Harper JW, Martin M. The catalytic mechanism of angiotensin converting enzyme and related zinc enzymes. J Cardiovasc Pharmacol. 1986; 8 Suppl 10:S29-34. PMID: 2438487.
    Citations: 1     Fields:    Translation:AnimalsCells
  76. Alderman EM, Lobb RR, Fett JW, Riordan JF, Bethune JL, Vallee BL. Angiogenic activity of human tumor plasma membrane components. Biochemistry. 1985 Dec 31; 24(27):7866-71. PMID: 2418873.
    Citations: 1     Fields:    Translation:HumansAnimalsCells
  77. Bicknell R, Schaeffer A, Auld DS, Riordan JF, Monnanni R, Bertini I. Protease susceptibility of zinc- and apo-carboxypeptidase A. Biochem Biophys Res Commun. 1985 Dec 17; 133(2):787-93. PMID: 3910041.
    Citations:    Fields:    Translation:Cells
  78. Strydom DJ, Fett JW, Lobb RR, Alderman EM, Bethune JL, Riordan JF, Vallee BL. Amino acid sequence of human tumor derived angiogenin. Biochemistry. 1985 Sep 24; 24(20):5486-94. PMID: 2866794.
    Citations: 94     Fields:    Translation:HumansAnimalsCells
  79. Fett JW, Strydom DJ, Lobb RR, Alderman EM, Bethune JL, Riordan JF, Vallee BL. Isolation and characterization of angiogenin, an angiogenic protein from human carcinoma cells. Biochemistry. 1985 Sep 24; 24(20):5480-6. PMID: 4074709.
    Citations: 252     Fields:    Translation:HumansAnimalsCells
  80. Kurachi K, Davie EW, Strydom DJ, Riordan JF, Vallee BL. Sequence of the cDNA and gene for angiogenin, a human angiogenesis factor. Biochemistry. 1985 Sep 24; 24(20):5494-9. PMID: 2866795.
    Citations: 60     Fields:    Translation:HumansCells
  81. Bünning P, Riordan JF. The functional role of zinc in angiotensin converting enzyme: implications for the enzyme mechanism. J Inorg Biochem. 1985 Jul; 24(3):183-98. PMID: 2995578.
    Citations: 13     Fields:    Translation:Animals
  82. Vallee BL, Riordan JF, Lobb RR, Higachi N, Fett JW, Crossley G, Bühler R, Budzik G, Breddam K, Bethune JL, et al. Tumor-derived angiogenesis factors from rat Walker 256 carcinoma: an experimental investigation and review. Experientia. 1985 Jan 15; 41(1):1-15. PMID: 2578407.
    Citations: 16     Fields:    Translation:AnimalsCells
  83. Shapiro R, Riordan JF. Inhibition of angiotensin converting enzyme: dependence on chloride. Biochemistry. 1984 Oct 23; 23(22):5234-40. PMID: 6095894.
    Citations: 10     Fields:    Translation:Animals
  84. Shapiro R, Riordan JF. Inhibition of angiotensin converting enzyme: mechanism and substrate dependence. Biochemistry. 1984 Oct 23; 23(22):5225-33. PMID: 6095893.
    Citations: 9     Fields:    Translation:AnimalsCells
  85. Pantoliano MW, Holmquist B, Riordan JF. Affinity chromatographic purification of angiotensin converting enzyme. Biochemistry. 1984 Feb 28; 23(5):1037-42. PMID: 6324855.
    Citations: 12     Fields:    Translation:Animals
  86. Shapiro R, Riordan JF. Critical lysine residue at the chloride binding site of angiotensin converting enzyme. Biochemistry. 1983 Nov 08; 22(23):5315-21. PMID: 6317019.
    Citations: 4     Fields:    Translation:AnimalsCells
  87. Shapiro R, Holmquist B, Riordan JF. Anion activation of angiotensin converting enzyme: dependence on nature of substrate. Biochemistry. 1983 Aug 02; 22(16):3850-7. PMID: 6311253.
    Citations: 12     Fields:    Translation:AnimalsCells
  88. Bünning P, Holmquist B, Riordan JF. Substrate specificity and kinetic characteristics of angiotensin converting enzyme. Biochemistry. 1983 Jan 04; 22(1):103-10. PMID: 6299330.
    Citations: 11     Fields:    Translation:AnimalsCells
  89. Bünning P, Riordan JF. Activation of angiotensin converting enzyme by monovalent anions. Biochemistry. 1983 Jan 04; 22(1):110-6. PMID: 6299331.
    Citations: 18     Fields:    Translation:AnimalsCells
  90. Kumamaru T, Riordan JF, Vallee BL. Determination of picogram quantities of zinc in zinc metalloproteins by atomic absorption spectrometry using a graphite furnace atomizer. Anal Biochem. 1982 Oct; 126(1):214-21. PMID: 7181113.
    Citations: 1     Fields:    Translation:Animals
  91. Kumamaru T, Riordan JF, Vallee BL. Low-pressure microwave-induced helium plasma emission spectrometry: determination of subnanogram quantities of zinc by use of a tungsten filament vaporization system. Anal Biochem. 1982 Oct; 126(1):208-13. PMID: 7181112.
    Citations:    Fields:    Translation:AnimalsCells
  92. Keung WM, Holmquist B, Riordan JF. Esterase activity of rabbit pulmonary angiotensin converting enzyme. Biochem Biophys Res Commun. 1980 Sep 16; 96(1):506-13. PMID: 6254517.
    Citations: 2     Fields:    Translation:Animals
  93. Cueni LB, Bazzone TJ, Riordan JF, Vallee BL. Affinity chromatographic sorting of carboxypeptidase A and its chemically modified derivatives. Anal Biochem. 1980 Sep 15; 107(2):341-9. PMID: 7435967.
    Citations: 2     Fields:    Translation:Cells
  94. Holmquist B, Bünning P, Riordan JF. A continuous spectrophotometric assay for angiotensin converting enzyme. Anal Biochem. 1979 Jun; 95(2):540-8. PMID: 222167.
    Citations: 45     Fields:    Translation:Cells
  95. Lee HM, Riordan JF. Does carboxypeptidase Y have intrinsic endopeptidase activity? Biochem Biophys Res Commun. 1978 Dec 14; 85(3):1135-42. PMID: 367372.
    Citations: 5     Fields:    Translation:Animals
  96. Bünning P, Holmquist B, Riordan JF. Functional residues at the active site of angiotensin converting enzyme. Biochem Biophys Res Commun. 1978 Aug 29; 83(4):1442-9. PMID: 212066.
    Citations: 6     Fields:    Translation:Cells
  97. Cueni L, Riordan JF. Functional tyrosyl residues of carboxypeptidase A. The effect of protein structure on the reactivity of tyrosine-198. Biochemistry. 1978 May 16; 17(10):1834-42. PMID: 566110.
    Citations: 1     Fields:    Translation:AnimalsCells
  98. Jörnvall H, Lange LG, Riordan JF, Vallee BL. Identification of a reactive arginyl residue in horse liver alcohol dehydrogenase. Biochem Biophys Res Commun. 1977 Jul 11; 77(1):73-8. PMID: 560849.
    Citations: 3     Fields:    Translation:AnimalsCells
  99. Riordan JF. The role of metals in enzyme activity. Ann Clin Lab Sci. 1977 Mar-Apr; 7(2):119-29. PMID: 192123.
    Citations: 19     Fields:    Translation:AnimalsCells
  100. Vallee BL, Riordan JF. Dynamics of local conformation and enzyme function. Ciba Found Symp. 1977; (60):197-223. PMID: 252452.
    Citations:    Fields:    Translation:Cells
  101. Riordan JF, Giese RW. Internal standards for amino acid analysis. Methods Enzymol. 1977; 47:31-40. PMID: 927189.
    Citations:    Fields:    
  102. Lobb RR, Stokes AM, Hill HA, Riordan JF. A functional arginine residue in rabbit-muscle aldolase. Eur J Biochem. 1976 Nov 15; 70(2):517-22. PMID: 1034558.
    Citations: 4     Fields:    Translation:AnimalsCells
  103. Muszynska G, Riordan JF. Chemical modification of carboxypeptidase A crystals. Nitration of tyrosine-248. Biochemistry. 1976 Jan 13; 15(1):46-51. PMID: 942853.
    Citations: 2     Fields:    Translation:AnimalsCells
  104. Nau H, Riordan JF. Gas chromatography-mass spectrometry for probing the structure and mechanism of action of enzyme active sites. The role of Glu-270 in carboxypeptidase A. Biochemistry. 1975 Dec 02; 14(24):5285-94. PMID: 1191637.
    Citations: 4     Fields:    Translation:Cells
  105. Borders CL, Riordan JF. An essential arginyl residue at the nucleotide binding site of creatine kinase. Biochemistry. 1975 Oct 21; 14(21):4699-704. PMID: 1237312.
    Citations: 23     Fields:    Translation:AnimalsCells
  106. Borders CL, Riordan JF, Auld DS. Essential arginyl residues in reverse transcriptase. Biochem Biophys Res Commun. 1975 Sep 16; 66(2):490-5. PMID: 52361.
    Citations: 6     Fields:    Translation:Cells
  107. Riordan JF, Scandurra R. Essential arginyl residues in aspartate aminotransferases. Biochem Biophys Res Commun. 1975 Sep 02; 66(1):417-24. PMID: 1164432.
    Citations: 7     Fields:    Translation:AnimalsCells
  108. Scandurra R, Polidoro G, Di Cola D, Politi L, Riordan JF. Role of tyrosine residues in mitochondrial aspartate aminotransferase from beef kidney. Biochemistry. 1975 Aug 12; 14(16):3701-6. PMID: 1172445.
    Citations: 3     Fields:    Translation:AnimalsCells
  109. Lange LG, Riordan JF, Vallee BL, Brändén CI. The role of arginyl residues in directing carboxymethylation of horse liver alcohol dehydrogenase. Biochemistry. 1975 Jul 29; 14(15):3497-502. PMID: 167828.
    Citations: 3     Fields:    Translation:AnimalsCells
  110. Lange LG, Riordan JF, Vallee BL. Functional arginyl residues as NADH binding sites of alcohol dehydrogenases. Biochemistry. 1974 Oct 08; 13(21):4361-70. PMID: 4370030.
    Citations: 14     Fields:    Translation:HumansAnimalsCells
  111. Daemen FJ, Riordan JF. Essential arginyl residues in Escherichia coli alkaline phosphatase. Biochemistry. 1974 Jul 02; 13(14):2865-71. PMID: 4601722.
    Citations: 15     Fields:    Translation:Cells
  112. Lange LG, Auld DS, Riordan JF. Substrate enantiomers. Modifiers of carboxypeptidase A activity. Biochemistry. 1974 Apr 23; 13(9):1983-6. PMID: 4858174.
    Citations:    Fields:    Translation:AnimalsCells
  113. Riordan JF, Muszynska G. Differences between the conformations of nitrotyrosyl-248 carboxypeptidase A in the crystalline state and in solution. Biochem Biophys Res Commun. 1974 Mar 25; 57(2):447-51. PMID: 4829403.
    Citations: 4     Fields:    Translation:Cells
  114. Riordan JF, Vallee BL. The functional roles of metals in metalloenzymes. Adv Exp Med Biol. 1974; 48(0):33-57. PMID: 4215300.
    Citations: 3     Fields:    Translation:HumansAnimalsCells
  115. Riordan JF. Functional arginyl residues in carboxypeptidase A. Modification with butanedione. Biochemistry. 1973 Sep 25; 12(20):3915-23. PMID: 4355543.
    Citations: 44     Fields:    Translation:AnimalsCells
  116. Wacker WE, Riordan JF, Snodgrass PJ, Chang LW, Morse LJ, O'Brien TF, Reddy WJ. The Holy Cross hepatitis outbreak: clinical and chemical abnormalities. Arch Intern Med. 1972 Sep; 130(3):357-60. PMID: 5055691.
    Citations: 2     Fields:    Translation:HumansPHPublic Health
  117. Riordan JF, Vallee BL. [36] Reactions with N-ethylmaleimide and p-mercuribenzoate. Methods Enzymol. 1972; 25:449-56. PMID: 23014425.
    Citations: 8     Fields:    Translation:Cells
  118. Riordan JF, Vallee BL. [44] Nitration with tetranitromethane. Methods Enzymol. 1972; 25:515-21. PMID: 23014433.
    Citations: 7     Fields:    
  119. Vallee BL, Riordan JF, Johansen JT, Livingston DM. Spectro-chemical probes for protein conformation and function. Cold Spring Harb Symp Quant Biol. 1972; 36:517-31. PMID: 4563862.
    Citations: 9     Fields:    Translation:Cells
  120. Riordan JF, Vallee BL. [41] acetylation. Methods Enzymol. 1972; 25:494-9. PMID: 23014430.
    Citations: 8     Fields:    Translation:Cells
  121. Riordan JF, Vallee BL. [45] Diazonium salts as specific reagents and probes of protein conformation. Methods Enzymol. 1972; 25:521-31. PMID: 23014434.
    Citations: 3     Fields:    Translation:Cells
  122. Riordan JF, Vallee BL. [42] o-acetyltyrosine. Methods Enzymol. 1972; 25:500-6. PMID: 23014431.
    Citations: 8     Fields:    
  123. Riordan JF, Livingston DM. Conformational and activity changes on subtilisin cleavage of carboxypeptidase A. Biochem Biophys Res Commun. 1971 Aug 06; 44(3):695-701. PMID: 5123207.
    Citations:    Fields:    Translation:Cells
  124. Riordan JF, Hayashida H. Chemical evidence for a functional carboxyl group in carboxypeptidase A. Biochem Biophys Res Commun. 1970 Oct 09; 41(1):122-7. PMID: 5459114.
    Citations: 3     Fields:    Translation:Cells
  125. Christen P, Riordan JF. Syncatalytic modification of a functional tyrosyl residue in aspartate aminotransferase. Biochemistry. 1970 Jul 21; 9(15):3025-34. PMID: 5529033.
    Citations: 8     Fields:    Translation:AnimalsCells
  126. Vallee BL, Riordan JF, Auld DS, Latt SA. Chemical approaches to the mode of action of carboxypeptidase A. Philos Trans R Soc Lond B Biol Sci. 1970 Feb 12; 257(813):215-30. PMID: 4399046.
    Citations: 1     Fields:    Translation:Cells
  127. Sokolovsky M, Harell D, Riordan JF. Reaction of tetranitromethane with sulfhydryl groups in proteins. Biochemistry. 1969 Dec; 8(12):4740-5. PMID: 4904041.
    Citations: 8     Fields:    Translation:Animals
  128. Riordan JF, Christen P. Carbanion intermediates in the reaction of yeast and muscle aldolase. Biochemistry. 1969 Jun; 8(6):2381-6. PMID: 5799131.
    Citations: 4     Fields:    Translation:AnimalsCells
  129. Vallee BL, Riordan JF. Chemical approaches to the properties of active sites of enzymes. Annu Rev Biochem. 1969; 38:733-94. PMID: 4896248.
    Citations: 27     Fields:    Translation:HumansAnimalsCells
  130. Vallee BL, Riordan JF, Bethune JL, Coombs TL, Auld DS, Sokolovsky M. A model for substrate binding and kinetics of carboxypeptidase A. Biochemistry. 1968 Oct; 7(10):3547-56. PMID: 5681464.
    Citations: 5     Fields:    Translation:Cells
  131. Vallee BL, Riordan JF. Chemical approaches to the mode of action of carboxypeptidase A. Brookhaven Symp Biol. 1968 Jun; 21(1):91-119. PMID: 5721305.
    Citations: 4     Fields:    Translation:Cells
  132. Christen P, Riordan JF. Reaction of an aldolase-substrate intermediate with tetranitromethane. Biochemistry. 1968 Apr; 7(4):1531-8. PMID: 5677840.
    Citations: 2     Fields:    Translation:Animals
  133. Riordan JF, Christen P. Reaction of tetranitromethane with protein sulfhydryl groups. Inactivation of aldolase. Biochemistry. 1968 Apr; 7(4):1525-30. PMID: 5677839.
    Citations: 4     Fields:    Translation:Animals
  134. Davies RC, Riordan JF, Auld DS, Vallee BL. Kinetics of carboxypeptidase A. I. Hydrolysis of carbobenzoxyglycyl-l-phenylalanine, benzoylglycyl-l-phenylalanine, and hippuryl-dl-beta-phenyllactic acid by metal-substituted and acetylated carboxypeptidases. Biochemistry. 1968 Mar; 7(3):1090-9. PMID: 5690560.
    Citations: 8     Fields:    Translation:Animals
  135. Riordan JF, Sokolovsky M, Vallee BL. The functional tyrosyl residues of carboxypeptidase A. Nitration with tetranitromethane. Biochemistry. 1967 Nov; 6(11):3609-17. PMID: 6073043.
    Citations: 5     Fields:    Translation:Cells
  136. Sokolovsky M, Riordan JF, Vallee BL. Conversion of 3-nitrotyrosine to 3-aminotyrosine in peptides and proteins. Biochem Biophys Res Commun. 1967 Apr 07; 27(1):20-5. PMID: 6048236.
    Citations: 35     Fields:    
  137. Riordan JF, Sokolovsky M, Vallee BL. Environmentally sensitive tyrosyl residues. Nitration with tetranitromethane. Biochemistry. 1967 Jan; 6(1):358-61. PMID: 6030334.
    Citations: 21     Fields:    
  138. Sokolovsky M, Riordan JF, Vallee BL. Tetranitromethane. A reagent for the nitration of tyrosyl residues in proteins. Biochemistry. 1966 Nov; 5(11):3582-9. PMID: 5339594.
    Citations: 79     Fields:    
  139. Riordan JF, Wacker WE, Vallee BL. "Buried" tyrosyl residues and the activity of trypsin. Nature. 1965 Dec 18; 208(5016):1209-11. PMID: 5870321.
    Citations: 2     Fields:    Translation:Cells
  140. RIORDAN JF, VALLEE BL. SUCCINYLCARBOXYPEPTIDASE. Biochemistry. 1964 Nov; 3:1768-74. PMID: 14235346.
    Citations: 9     Fields:    Translation:Cells
  141. RIORDAN JF, VALLEE BL. ACETYLCARBOXYPEPTIDASE. Biochemistry. 1963 Nov-Dec; 2:1460-8. PMID: 14093927.
    Citations: 7     Fields:    Translation:Animals
    Citations: 22     Fields:    Translation:Animals
  143. VALLEE BL, RIORDAN JF, COLEMAN JE. Carboxypeptidase A: approaches to the chemical nature of the active center and the mechanisms of action. Proc Natl Acad Sci U S A. 1963 Jan 15; 49:109-16. PMID: 13995911; PMCID: PMC300637.
    Citations: 9     Fields:    Translation:Humans
Local representatives can answer questions about the Profiles website or help with editing a profile or issues with profile data. For assistance with this profile: HMS/HSDM faculty should contact contactcatalyst.harvard.edu. For faculty or fellow appointment updates and changes, please ask your appointing department to contact HMS. For fellow personal and demographic information, contact HMS Human Resources at human_resourceshms.harvard.edu. For faculty personal and demographic information, contact HMS Office for Faculty Affairs at facappthms.harvard.edu.
Riordan's Networks
Click the
buttons for more information and interactive visualizations!
Concepts (511)
Co-Authors (5)
Similar People (60)
Same Department 
Physical Neighbors
Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.