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Joseph J Locascio, PH.D.

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Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Szabari MV, Takahashi K, Feng Y, Locascio JJ, Chao W, Carter EA, Vidal Melo MF, Musch G. Relation between Respiratory Mechanics, Inflammation, and Survival in Experimental Mechanical Ventilation. Am J Respir Cell Mol Biol. 2019 Feb; 60(2):179-188. PMID: 30199644.
    Citations:    Fields:    
  2. Marshall GA, Aghjayan SL, Dekhtyar M, Locascio JJ, Jethwani K, Amariglio RE, Czaja SJ, Loewenstein DA, Johnson KA, Sperling RA, Rentz DM. Measuring instrumental activities of daily living in non-demented elderly: a comparison of the new performance-based Harvard Automated Phone Task with other functional assessments. Alzheimers Res Ther. 2019 Jan 10; 11(1):4. PMID: 30630529.
    Citations:    Fields:    
  3. Dong X, Liao Z, Gritsch D, Hadzhiev Y, Bai Y, Locascio JJ, Guennewig B, Liu G, Blauwendraat C, Wang T, Adler CH, Hedreen JC, Faull RLM, Frosch MP, Nelson PT, Rizzu P, Cooper AA, Heutink P, Beach TG, Mattick JS, Müller F, Scherzer CR. Publisher Correction: Enhancers active in dopamine neurons are a primary link between genetic variation and neuropsychiatric disease. Nat Neurosci. 2019 Jan; 22(1):144-147. PMID: 30482917.
    Citations:    Fields:    
  4. Kimizuka Y, Katagiri W, Locascio JJ, Shigeta A, Sasaki Y, Shibata M, Morse K, Sîrbulescu RF, Miyatake M, Reeves P, Suematsu M, Gelfand J, Brauns T, Poznansky MC, Tsukada K, Kashiwagi S. Brief Exposure of Skin to Near-Infrared Laser Modulates Mast Cell Function and Augments the Immune Response. J Immunol. 2018 Dec 15; 201(12):3587-3603. PMID: 30420435.
    Citations:    
  5. Erler KS, Juengst SB, Whiteneck GG, Locascio JJ, Bogner JA, Kaminski J, Giacino JT. The Association of Rehospitalization With Participation 5 Years After Traumatic Brain Injury. J Head Trauma Rehabil. 2018 Nov/Dec; 33(6):E77-E84. PMID: 29601342.
    Citations:    Fields:    
  6. Dong X, Liao Z, Gritsch D, Hadzhiev Y, Bai Y, Locascio JJ, Guennewig B, Liu G, Blauwendraat C, Wang T, Adler CH, Hedreen JC, Faull RLM, Frosch MP, Nelson PT, Rizzu P, Cooper AA, Heutink P, Beach TG, Mattick JS, Müller F, Scherzer CR. Enhancers active in dopamine neurons are a primary link between genetic variation and neuropsychiatric disease. Nat Neurosci. 2018 Oct; 21(10):1482-1492. PMID: 30224808.
    Citations:    Fields:    
  7. Gelfand JA, Nazarian RM, Kashiwagi S, Brauns T, Martin B, Kimizuka Y, Korek S, Botvinick E, Elkins K, Thomas L, Locascio J, Parry B, Kelly KM, Poznansky MC. A pilot clinical trial of a near-infrared laser vaccine adjuvant: safety, tolerability, and cutaneous immune cell trafficking. FASEB J. 2019 Feb; 33(2):3074-3081. PMID: 30192655.
    Citations:    Fields:    
  8. Erler KS, Whiteneck GG, Juengst SB, Locascio JJ, Bogner JA, Kaminski J, Giacino JT. Predicting the Trajectory of Participation After Traumatic Brain Injury: A Longitudinal Analysis. J Head Trauma Rehabil. 2018 Jul/Aug; 33(4):257-265. PMID: 29385019.
    Citations:    Fields:    
  9. Hariton E, Locascio JJ. Randomised controlled trials - the gold standard for effectiveness research: Study design: randomised controlled trials. BJOG. 2018 12; 125(13):1716. PMID: 29916205.
    Citations:    Fields:    
  10. Munro CE, Donovan NJ, Amariglio RE, Papp KV, Marshall GA, Rentz DM, Pascual-Leone A, Sperling RA, Locascio JJ, Vannini P. The Impact of Awareness of and Concern About Memory Performance on the Prediction of Progression From Mild Cognitive Impairment to Alzheimer Disease Dementia. Am J Geriatr Psychiatry. 2018 Aug; 26(8):896-904. PMID: 29866588.
    Citations:    Fields:    
  11. Trombetta BA, Carlyle BC, Koenig AM, Shaw LM, Trojanowski JQ, Wolk DA, Locascio JJ, Arnold SE. The technical reliability and biotemporal stability of cerebrospinal fluid biomarkers for profiling multiple pathophysiologies in Alzheimer's disease. PLoS One. 2018; 13(3):e0193707. PMID: 29505610.
    Citations: 2     Fields:    Translation:Humans
  12. Donovan NJ, Locascio JJ, Marshall GA, Gatchel J, Hanseeuw BJ, Rentz DM, Johnson KA, Sperling RA. Longitudinal Association of Amyloid Beta and Anxious-Depressive Symptoms in Cognitively Normal Older Adults. Am J Psychiatry. 2018 Jun 01; 175(6):530-537. PMID: 29325447.
    Citations: 2     Fields:    
  13. Fiechtner L, Perkins M, Biggs V, Langhans N, Sharifi M, O'Connor G, Price S, Locascio J, Kuhlthau K, Kwass JA, Nelson C, Land T, Longjohn M, Lawson V, Hohman K, Taveras EM. Rationale and design of the Clinic and Community Approaches to Healthy Weight Randomized Trial. Contemp Clin Trials. 2018 Apr; 67:16-22. PMID: 29330083.
    Citations:    Fields:    
  14. Locascio JJ. Rejoinder to Responses to "Results-Blind Publishing". Basic Appl Soc Psych. 2017; 39(5):258-261. PMID: 30135613.
    Citations:    
  15. Locascio JJ. Results Blind Science Publishing. Basic Appl Soc Psych. 2017; 39(5):239-246. PMID: 29780193.
    Citations:    
  16. Mittal S, Bjørnevik K, Im DS, Flierl A, Dong X, Locascio JJ, Abo KM, Long E, Jin M, Xu B, Xiang YK, Rochet JC, Engeland A, Rizzu P, Heutink P, Bartels T, Selkoe DJ, Caldarone BJ, Glicksman MA, Khurana V, Schüle B, Park DS, Riise T, Scherzer CR. ß2-Adrenoreceptor is a regulator of the a-synuclein gene driving risk of Parkinson's disease. Science. 2017 09 01; 357(6354):891-898. PMID: 28860381.
    Citations: 25     Fields:    Translation:HumansAnimalsCells
  17. Morse K, Kimizuka Y, Chan MPK, Shibata M, Shimaoka Y, Takeuchi S, Forbes B, Nirschl C, Li B, Zeng Y, Bronson RT, Katagiri W, Shigeta A, Sîrbulescu RF, Chen H, Tan RYY, Tsukada K, Brauns T, Gelfand J, Sluder A, Locascio JJ, Poznansky MC, Anandasabapathy N, Kashiwagi S. Near-Infrared 1064 nm Laser Modulates Migratory Dendritic Cells To Augment the Immune Response to Intradermal Influenza Vaccine. J Immunol. 2017 08 15; 199(4):1319-1332. PMID: 28710250.
    Citations: 1     Fields:    Translation:AnimalsCellsPHPublic Health
  18. Liu G, Locascio JJ, Corvol JC, Boot B, Liao Z, Page K, Franco D, Burke K, Jansen IE, Trisini-Lipsanopoulos A, Winder-Rhodes S, Tanner CM, Lang AE, Eberly S, Elbaz A, Brice A, Mangone G, Ravina B, Shoulson I, Cormier-Dequaire F, Heutink P, van Hilten JJ, Barker RA, Williams-Gray CH, Marinus J, Scherzer CR. Prediction of cognition in Parkinson's disease with a clinical-genetic score: a longitudinal analysis of nine cohorts. Lancet Neurol. 2017 08; 16(8):620-629. PMID: 28629879.
    Citations: 7     Fields:    Translation:Humans
  19. Gatchel JR, Donovan NJ, Locascio JJ, Becker JA, Rentz DM, Sperling RA, Johnson KA, Marshall GA. Regional 18F-Fluorodeoxyglucose Hypometabolism is Associated with Higher Apathy Scores Over Time in Early Alzheimer Disease. Am J Geriatr Psychiatry. 2017 Jul; 25(7):683-693. PMID: 28410856.
    Citations: 2     Fields:    Translation:Humans
  20. Gatchel JR, Donovan NJ, Locascio JJ, Schultz AP, Becker JA, Chhatwal J, Papp KV, Amariglio RE, Rentz DM, Blacker D, Sperling RA, Johnson KA, Marshall GA. Depressive Symptoms and Tau Accumulation in the Inferior Temporal Lobe and Entorhinal Cortex in Cognitively Normal Older Adults: A Pilot Study. J Alzheimers Dis. 2017; 59(3):975-985. PMID: 28697559.
    Citations: 2     Fields:    Translation:Humans
  21. Marshall GA, Aghjayan SL, Dekhtyar M, Locascio JJ, Jethwani K, Amariglio RE, Johnson KA, Sperling RA, Rentz DM. Activities of daily living measured by the Harvard Automated Phone Task track with cognitive decline over time in non-demented elderly. J Prev Alzheimers Dis. 2017; 4(2):81-86. PMID: 29124043.
    Citations: 2     Fields:    
  22. Liu G, Boot B, Locascio JJ, Jansen IE, Winder-Rhodes S, Eberly S, Elbaz A, Brice A, Ravina B, van Hilten JJ, Cormier-Dequaire F, Corvol JC, Barker RA, Heutink P, Marinus J, Williams-Gray CH, Scherzer CR. Specifically neuropathic Gaucher's mutations accelerate cognitive decline in Parkinson's. Ann Neurol. 2016 Nov; 80(5):674-685. PMID: 27717005.
    Citations: 14     Fields:    Translation:Humans
  23. Gomperts SN, Locascio JJ, Makaretz SJ, Schultz A, Caso C, Vasdev N, Sperling R, Growdon JH, Dickerson BC, Johnson K. Tau Positron Emission Tomographic Imaging in the Lewy Body Diseases. JAMA Neurol. 2016 Nov 01; 73(11):1334-1341. PMID: 27654968.
    Citations: 29     Fields:    Translation:Humans
  24. Mukerji SS, Locascio JJ, Misra V, Lorenz DR, Holman A, Dutta A, Penugonda S, Wolinsky SM, Gabuzda D. Lipid Profiles and APOE4 Allele Impact Midlife Cognitive Decline in HIV-Infected Men on Antiretroviral Therapy. Clin Infect Dis. 2016 10 15; 63(8):1130-1139. PMID: 27448678.
    Citations: 2     Fields:    Translation:Humans
  25. Maye JE, Betensky RA, Gidicsin CM, Locascio J, Becker JA, Pepin L, Carmasin J, Rentz DM, Marshall GA, Blacker D, Sperling RA, Johnson KA. Maternal dementia age at onset in relation to amyloid burden in non-demented elderly offspring. Neurobiol Aging. 2016 Apr; 40:61-67. PMID: 26973104.
    Citations: 2     Fields:    Translation:Humans
  26. Gomperts SN, Marquie M, Locascio JJ, Bayer S, Johnson KA, Growdon JH. PET Radioligands Reveal the Basis of Dementia in Parkinson's Disease and Dementia with Lewy Bodies. Neurodegener Dis. 2016; 16(1-2):118-24. PMID: 26655867.
    Citations: 9     Fields:    
  27. Locascio JJ, Eberly S, Liao Z, Liu G, Hoesing AN, Duong K, Trisini-Lipsanopoulos A, Dhima K, Hung AY, Flaherty AW, Schwarzschild MA, Hayes MT, Wills AM, Shivraj Sohur U, Mejia NI, Selkoe DJ, Oakes D, Shoulson I, Dong X, Marek K, Zheng B, Ivinson A, Hyman BT, Growdon JH, Sudarsky LR, Schlossmacher MG, Ravina B, Scherzer CR. Association between a-synuclein blood transcripts and early, neuroimaging-supported Parkinson's disease. Brain. 2015 Sep; 138(Pt 9):2659-71. PMID: 26220939; PMCID: PMC4643625.
    Citations: 16     Fields:    Translation:Humans
  28. Gidicsin CM, Maye JE, Locascio JJ, Pepin LC, Philiossaint M, Becker JA, Younger AP, Dekhtyar M, Schultz AP, Amariglio RE, Marshall GA, Rentz DM, Hedden T, Sperling RA, Johnson KA. Cognitive activity relates to cognitive performance but not to Alzheimer disease biomarkers. Neurology. 2015 Jul 07; 85(1):48-55. PMID: 26062627; PMCID: PMC4501938.
    Citations: 5     Fields:    Translation:Humans
  29. Oreskovic NM, Perrin JM, Robinson AI, Locascio JJ, Blossom J, Chen ML, Winickoff JP, Field AE, Green C, Goodman E. Adolescents' use of the built environment for physical activity. BMC Public Health. 2015 Mar 15; 15:251. PMID: 25880654; PMCID: PMC4369364.
    Citations: 13     Fields:    Translation:Humans
  30. Lorius N, Locascio JJ, Rentz DM, Johnson KA, Sperling RA, Viswanathan A, Marshall GA. Vascular disease and risk factors are associated with cognitive decline in the alzheimer disease spectrum. Alzheimer Dis Assoc Disord. 2015 Jan-Mar; 29(1):18-25. PMID: 24787033; PMCID: PMC4366000.
    Citations: 6     Fields:    Translation:Humans
  31. Marshall GA, Zoller AS, Lorius N, Amariglio RE, Locascio JJ, Johnson KA, Sperling RA, Rentz DM. Functional Activities Questionnaire Items that Best Discriminate and Predict Progression from Clinically Normal to Mild Cognitive Impairment. Curr Alzheimer Res. 2015; 12(5):493-502. PMID: 26017560; PMCID: PMC4448081.
    Citations: 3     Fields:    Translation:Humans
  32. Guercio BJ, Donovan NJ, Munro CE, Aghjayan SL, Wigman SE, Locascio JJ, Amariglio RE, Rentz DM, Johnson KA, Sperling RA, Marshall GA. The Apathy Evaluation Scale: A Comparison of Subject, Informant, and Clinician Report in Cognitively Normal Elderly and Mild Cognitive Impairment. J Alzheimers Dis. 2015; 47(2):421-32. PMID: 26401564; PMCID: PMC4602169.
    Citations: 5     Fields:    Translation:Humans
  33. Marquie M, Locascio JJ, Rentz DM, Becker JA, Hedden T, Johnson KA, Growdon JH, Gomperts SN. Striatal and extrastriatal dopamine transporter levels relate to cognition in Lewy body diseases: an (11)C altropane positron emission tomography study. Alzheimers Res Ther. 2014; 6(5-8):52. PMID: 25429309; PMCID: PMC4245149.
    Citations: 9     Fields:    
  34. Mehanna R, Scherzer CR, Ding H, Locascio JJ. Unrecognized vitamin D3 deficiency is common in Parkinson disease: Harvard Biomarker study. Neurology. 2014 May 06; 82(18):1666; discussion 1666. PMID: 24799519.
    Citations: 4     Fields:    Translation:Humans
  35. Locascio JJ. The reality of racism based on the illusion of "race". Am Psychol. 2014 Apr; 69(3):310-1. PMID: 24750090.
    Citations:    Fields:    Translation:Humans
  36. Donovan NJ, Amariglio RE, Zoller AS, Rudel RK, Gomez-Isla T, Blacker D, Hyman BT, Locascio JJ, Johnson KA, Sperling RA, Marshall GA, Rentz DM. Subjective cognitive concerns and neuropsychiatric predictors of progression to the early clinical stages of Alzheimer disease. Am J Geriatr Psychiatry. 2014 Dec; 22(12):1642-51. PMID: 24698445; PMCID: PMC4145054.
    Citations: 25     Fields:    Translation:Humans
  37. Marshall GA, Zoller AS, Kelly KE, Amariglio RE, Locascio JJ, Johnson KA, Sperling RA, Rentz DM. Everyday cognition scale items that best discriminate between and predict progression from clinically normal to mild cognitive impairment. Curr Alzheimer Res. 2014; 11(9):853-61. PMID: 25274110; PMCID: PMC4247808.
    Citations: 6     Fields:    Translation:Humans
  38. Roy K, Pepin LC, Philiossaint M, Lorius N, Becker JA, Locascio JJ, Rentz DM, Sperling RA, Johnson KA, Marshall GA. Regional fluorodeoxyglucose metabolism and instrumental activities of daily living across the Alzheimer's disease spectrum. J Alzheimers Dis. 2014; 42(1):291-300. PMID: 24898635; PMCID: PMC4133312.
    Citations: 11     Fields:    Translation:Humans
  39. Marshall GA, Lorius N, Locascio JJ, Hyman BT, Rentz DM, Johnson KA, Sperling RA. Regional cortical thinning and cerebrospinal biomarkers predict worsening daily functioning across the Alzheimer's disease spectrum. J Alzheimers Dis. 2014; 41(3):719-28. PMID: 24685624; PMCID: PMC4111766.
    Citations: 14     Fields:    Translation:Humans
  40. Zoller AS, Gaal IM, Royer CA, Locascio JJ, Amariglio RE, Blacker D, Okereke OI, Johnson KA, Sperling RA, Rentz DM, Marshall GA. SIST-M-IR activities of daily living items that best discriminate clinically normal elderly from those with mild cognitive impairment. Curr Alzheimer Res. 2014; 11(8):785-91. PMID: 25212917; PMCID: PMC4163929.
    Citations: 4     Fields:    Translation:Humans
  41. Ding H, Dhima K, Lockhart KC, Locascio JJ, Hoesing AN, Duong K, Trisini-Lipsanopoulos A, Hayes MT, Sohur US, Wills AM, Mollenhauer B, Flaherty AW, Hung AY, Mejia N, Khurana V, Gomperts SN, Selkoe DJ, Schwarzschild MA, Schlossmacher MG, Hyman BT, Sudarsky LR, Growdon JH, Scherzer CR. Unrecognized vitamin D3 deficiency is common in Parkinson disease: Harvard Biomarker Study. Neurology. 2013 Oct 22; 81(17):1531-7. PMID: 24068787; PMCID: PMC3888173.
    Citations: 22     Fields:    Translation:Humans
  42. Donovan NJ, Wadsworth LP, Lorius N, Locascio JJ, Rentz DM, Johnson KA, Sperling RA, Marshall GA. Regional cortical thinning predicts worsening apathy and hallucinations across the Alzheimer disease spectrum. Am J Geriatr Psychiatry. 2014 Nov; 22(11):1168-79. PMID: 23890751; PMCID: PMC3960369.
    Citations: 18     Fields:    Translation:Humans
  43. Herskovits AZ, Locascio JJ, Peskind ER, Li G, Hyman BT. A Luminex assay detects amyloid ß oligomers in Alzheimer's disease cerebrospinal fluid. PLoS One. 2013; 8(7):e67898. PMID: 23844122; PMCID: PMC3699502.
    Citations: 20     Fields:    Translation:HumansCells
  44. Gomperts SN, Locascio JJ, Rentz D, Santarlasci A, Marquie M, Johnson KA, Growdon JH. Amyloid is linked to cognitive decline in patients with Parkinson disease without dementia. Neurology. 2013 Jan 01; 80(1):85-91. PMID: 23243071; PMCID: PMC3589197.
    Citations: 48     Fields:    Translation:Humans
  45. Wadsworth LP, Lorius N, Donovan NJ, Locascio JJ, Rentz DM, Johnson KA, Sperling RA, Marshall GA. Neuropsychiatric symptoms and global functional impairment along the Alzheimer's continuum. Dement Geriatr Cogn Disord. 2012; 34(2):96-111. PMID: 22922821; PMCID: PMC3549662.
    Citations: 25     Fields:    Translation:Humans
  46. Gomperts SN, Locascio JJ, Marquie M, Santarlasci AL, Rentz DM, Maye J, Johnson KA, Growdon JH. Brain amyloid and cognition in Lewy body diseases. Mov Disord. 2012 Jul; 27(8):965-73. PMID: 22693110; PMCID: PMC3725259.
    Citations: 38     Fields:    Translation:Humans
  47. Shirk SD, Mitchell MB, Shaughnessy LW, Sherman JC, Locascio JJ, Weintraub S, Atri A. A web-based normative calculator for the uniform data set (UDS) neuropsychological test battery. Alzheimers Res Ther. 2011 Nov 11; 3(6):32. PMID: 22078663; PMCID: PMC3308021.
    Citations: 40     Fields:    
  48. Locascio JJ, Atri A. An overview of longitudinal data analysis methods for neurological research. Dement Geriatr Cogn Dis Extra. 2011 Jan; 1(1):330-57. PMID: 22203825; PMCID: PMC3243635.
    Citations: 25     
  49. Hu Y, Chopra V, Chopra R, Locascio JJ, Liao Z, Ding H, Zheng B, Matson WR, Ferrante RJ, Rosas HD, Hersch SM, Scherzer CR. Transcriptional modulator H2A histone family, member Y (H2AFY) marks Huntington disease activity in man and mouse. Proc Natl Acad Sci U S A. 2011 Oct 11; 108(41):17141-6. PMID: 21969577; PMCID: PMC3193232.
    Citations: 28     Fields:    Translation:HumansAnimalsCTClinical Trials
  50. O'Brien LM, Ziegler DA, Deutsch CK, Frazier JA, Herbert MR, Locascio JJ. Statistical adjustments for brain size in volumetric neuroimaging studies: some practical implications in methods. Psychiatry Res. 2011 Aug 30; 193(2):113-22. PMID: 21684724; PMCID: PMC3510982.
    Citations: 20     Fields:    Translation:Humans
  51. Farabaugh AH, Locascio JJ, Yap L, Fava M, Bitran S, Sousa JL, Growdon JH. Assessing depression and factors possibly associated with depression during the course of Parkinson's disease. Ann Clin Psychiatry. 2011 Aug; 23(3):171-7. PMID: 21808748; PMCID: PMC3164778.
    Citations:    Fields:    Translation:Humans
  52. Atri A, O'Brien JL, Sreenivasan A, Rastegar S, Salisbury S, DeLuca AN, O'Keefe KM, LaViolette PS, Rentz DM, Locascio JJ, Sperling RA. Test-retest reliability of memory task functional magnetic resonance imaging in Alzheimer disease clinical trials. Arch Neurol. 2011 May; 68(5):599-606. PMID: 21555634; PMCID: PMC3291175.
    Citations: 14     Fields:    Translation:Humans
  53. Marshall GA, Rentz DM, Frey MT, Locascio JJ, Johnson KA, Sperling RA. Executive function and instrumental activities of daily living in mild cognitive impairment and Alzheimer's disease. Alzheimers Dement. 2011 May; 7(3):300-8. PMID: 21575871; PMCID: PMC3096844.
    Citations: 53     Fields:    Translation:Humans
  54. Mollenhauer B, Locascio JJ, Schulz-Schaeffer W, Sixel-Döring F, Trenkwalder C, Schlossmacher MG. a-Synuclein and tau concentrations in cerebrospinal fluid of patients presenting with parkinsonism: a cohort study. Lancet Neurol. 2011 Mar; 10(3):230-40. PMID: 21317042.
    Citations: 140     Fields:    Translation:Humans
  55. Putcha D, O'Keefe K, LaViolette P, O'Brien J, Greve D, Rentz DM, Locascio J, Atri A, Sperling R. Reliability of functional magnetic resonance imaging associative encoding memory paradigms in non-demented elderly adults. Hum Brain Mapp. 2011 Dec; 32(12):2027-44. PMID: 21259385; PMCID: PMC3551453.
    Citations: 16     Fields:    Translation:Humans
  56. Zheng B, Liao Z, Locascio JJ, Lesniak KA, Roderick SS, Watt ML, Eklund AC, Zhang-James Y, Kim PD, Hauser MA, Grünblatt E, Moran LB, Mandel SA, Riederer P, Miller RM, Federoff HJ, Wüllner U, Papapetropoulos S, Youdim MB, Cantuti-Castelvetri I, Young AB, Vance JM, Davis RL, Hedreen JC, Adler CH, Beach TG, Graeber MB, Middleton FA, Rochet JC, Scherzer CR. PGC-1a, a potential therapeutic target for early intervention in Parkinson's disease. Sci Transl Med. 2010 Oct 06; 2(52):52ra73. PMID: 20926834; PMCID: PMC3129986.
    Citations: 212     Fields:    Translation:HumansCells
  57. Serrano-Pozo A, Vega GL, Lütjohann D, Locascio JJ, Tennis MK, Deng A, Atri A, Hyman BT, Irizarry MC, Growdon JH. Effects of simvastatin on cholesterol metabolism and Alzheimer disease biomarkers. Alzheimer Dis Assoc Disord. 2010 Jul-Sep; 24(3):220-6. PMID: 20473136; PMCID: PMC3694274.
    Citations: 13     Fields:    Translation:HumansCTClinical Trials
  58. Rentz DM, Locascio JJ, Becker JA, Moran EK, Eng E, Buckner RL, Sperling RA, Johnson KA. Cognition, reserve, and amyloid deposition in normal aging. Ann Neurol. 2010 Mar; 67(3):353-64. PMID: 20373347.
    Citations: 133     Fields:    Translation:Humans
  59. Farabaugh A, Locascio JJ, Yap L, Growdon J, Fava M, Crawford C, Matthews J, McCutchen J, Buchin J, Pava J, Alpert JE. Cognitive-behavioral therapy for patients with Parkinson's disease and comorbid major depressive disorder. Psychosomatics. 2010 Mar-Apr; 51(2):124-9. PMID: 20332287.
    Citations: 14     Fields:    Translation:Humans
  60. Farabaugh AH, Locascio JJ, Yap L, Weintraub D, McDonald WM, Agoston M, Alpert JE, Growdon J, Fava M. Pattern of depressive symptoms in Parkinson's disease. Psychosomatics. 2009 Sep-Oct; 50(5):448-54. PMID: 19855029; PMCID: PMC3529169.
    Citations: 3     Fields:    Translation:Humans
  61. Freeman SH, Kandel R, Cruz L, Rozkalne A, Newell K, Frosch MP, Hedley-Whyte ET, Locascio JJ, Lipsitz LA, Hyman BT. Preservation of neuronal number despite age-related cortical brain atrophy in elderly subjects without Alzheimer disease. J Neuropathol Exp Neurol. 2008 Dec; 67(12):1205-12. PMID: 19018241; PMCID: PMC2734185.
    Citations: 47     Fields:    Translation:HumansCells
  62. Wonderlick JS, Ziegler DA, Hosseini-Varnamkhasti P, Locascio JJ, Bakkour A, van der Kouwe A, Triantafyllou C, Corkin S, Dickerson BC. Reliability of MRI-derived cortical and subcortical morphometric measures: effects of pulse sequence, voxel geometry, and parallel imaging. Neuroimage. 2009 Feb 15; 44(4):1324-33. PMID: 19038349; PMCID: PMC2739882.
    Citations: 67     Fields:    Translation:Humans
  63. Gomperts SN, Rentz DM, Moran E, Becker JA, Locascio JJ, Klunk WE, Mathis CA, Elmaleh DR, Shoup T, Fischman AJ, Hyman BT, Growdon JH, Johnson KA. Imaging amyloid deposition in Lewy body diseases. Neurology. 2008 Sep 16; 71(12):903-10. PMID: 18794492; PMCID: PMC2637553.
    Citations: 120     Fields:    Translation:Humans
  64. Atri A, Shaughnessy LW, Locascio JJ, Growdon JH. Long-term course and effectiveness of combination therapy in Alzheimer disease. Alzheimer Dis Assoc Disord. 2008 Jul-Sep; 22(3):209-21. PMID: 18580597; PMCID: PMC2718545.
    Citations: 66     Fields:    Translation:HumansCTClinical Trials
  65. Mollenhauer B, Cullen V, Kahn I, Krastins B, Outeiro TF, Pepivani I, Ng J, Schulz-Schaeffer W, Kretzschmar HA, McLean PJ, Trenkwalder C, Sarracino DA, Vonsattel JP, Locascio JJ, El-Agnaf OM, Schlossmacher MG. Direct quantification of CSF alpha-synuclein by ELISA and first cross-sectional study in patients with neurodegeneration. Exp Neurol. 2008 Oct; 213(2):315-25. PMID: 18625222.
    Citations: 103     Fields:    Translation:HumansAnimalsCells
  66. Locascio JJ, Fukumoto H, Yap L, Bottiglieri T, Growdon JH, Hyman BT, Irizarry MC. Plasma amyloid beta-protein and C-reactive protein in relation to the rate of progression of Alzheimer disease. Arch Neurol. 2008 Jun; 65(6):776-85. PMID: 18541797; PMCID: PMC2662621.
    Citations: 28     Fields:    Translation:Humans
  67. Mollenhauer B, Steinacker P, Bahn E, Bibl M, Brechlin P, Schlossmacher MG, Locascio JJ, Wiltfang J, Kretzschmar HA, Poser S, Trenkwalder C, Otto M. Serum heart-type fatty acid-binding protein and cerebrospinal fluid tau: marker candidates for dementia with Lewy bodies. Neurodegener Dis. 2007; 4(5):366-75. PMID: 17622779.
    Citations: 15     Fields:    Translation:Humans
  68. Scherzer CR, Eklund AC, Morse LJ, Liao Z, Locascio JJ, Fefer D, Schwarzschild MA, Schlossmacher MG, Hauser MA, Vance JM, Sudarsky LR, Standaert DG, Growdon JH, Jensen RV, Gullans SR. Molecular markers of early Parkinson's disease based on gene expression in blood. Proc Natl Acad Sci U S A. 2007 Jan 16; 104(3):955-60. PMID: 17215369; PMCID: PMC1766335.
    Citations: 138     Fields:    Translation:Humans
  69. Tokuda T, Salem SA, Allsop D, Mizuno T, Nakagawa M, Qureshi MM, Locascio JJ, Schlossmacher MG, El-Agnaf OM. Decreased alpha-synuclein in cerebrospinal fluid of aged individuals and subjects with Parkinson's disease. Biochem Biophys Res Commun. 2006 Oct 13; 349(1):162-6. PMID: 16930553.
    Citations: 104     Fields:    Translation:Humans
  70. Irizarry MC, Gurol ME, Raju S, Diaz-Arrastia R, Locascio JJ, Tennis M, Hyman BT, Growdon JH, Greenberg SM, Bottiglieri T. Association of homocysteine with plasma amyloid beta protein in aging and neurodegenerative disease. Neurology. 2005 Nov 08; 65(9):1402-8. PMID: 16275827.
    Citations: 28     Fields:    Translation:Humans
  71. Atri A, Locascio JJ, Lin JM, Yap L, Dickerson BC, Grodstein F, Irizarry MC, Growdon JH, Greenberg SM. Prevalence and effects of lobar microhemorrhages in early-stage dementia. Neurodegener Dis. 2005; 2(6):305-12. PMID: 16909013.
    Citations: 7     Fields:    Translation:Humans
  72. Skotko BG, Kensinger EA, Locascio JJ, Einstein G, Rubin DC, Tupler LA, Krendl A, Corkin S. Puzzling thoughts for H. M.: can new semantic information be anchored to old semantic memories? Neuropsychology. 2004 Oct; 18(4):756-69. PMID: 15506844.
    Citations: 13     Fields:    Translation:Humans
  73. Fukumoto H, Tennis M, Locascio JJ, Hyman BT, Growdon JH, Irizarry MC. Age but not diagnosis is the main predictor of plasma amyloid beta-protein levels. Arch Neurol. 2003 Jul; 60(7):958-64. PMID: 12873852.
    Citations: 74     Fields:    Translation:Humans
  74. Kensinger EA, Shearer DK, Locascio JJ, Growdon JH, Corkin S. Working memory in mild Alzheimer's disease and early Parkinson's disease. Neuropsychology. 2003 Apr; 17(2):230-9. PMID: 12803428.
    Citations: 23     Fields:    Translation:HumansCTClinical Trials
  75. Locascio JJ, Corkin S, Growdon JH. Relation between clinical characteristics of Parkinson's disease and cognitive decline. J Clin Exp Neuropsychol. 2003 Feb; 25(1):94-109. PMID: 12607175.
    Citations: 20     Fields:    Translation:Humans
  76. Cha JH, Farrell LA, Ahmed SF, Frey A, Hsiao-Ashe KK, Young AB, Penney JB, Locascio JJ, Hyman BT, Irizarry MC. Glutamate receptor dysregulation in the hippocampus of transgenic mice carrying mutated human amyloid precursor protein. Neurobiol Dis. 2001 Feb; 8(1):90-102. PMID: 11162243.
    Citations: 4     Fields:    Translation:HumansAnimals
  77. Irizarry MC, Locascio JJ, Hyman BT. beta-site APP cleaving enzyme mRNA expression in APP transgenic mice: anatomical overlap with transgene expression and static levels with aging. Am J Pathol. 2001 Jan; 158(1):173-7. PMID: 11141490; PMCID: PMC1850271.
    Citations: 19     Fields:    Translation:HumansAnimalsCells
  78. Binetti G, Locascio JJ, Corkin S, Vonsattel JP, Growdon JH. Differences between Pick disease and Alzheimer disease in clinical appearance and rate of cognitive decline. Arch Neurol. 2000 Feb; 57(2):225-32. PMID: 10681082.
    Citations: 16     Fields:    Translation:HumansCTClinical Trials
  79. Rebeck GW, Cheung BS, Growdon WB, Deng A, Akuthota P, Locascio J, Greenberg SM, Hyman BT. Lack of independent associations of apolipoprotein E promoter and intron 1 polymorphisms with Alzheimer's disease. Neurosci Lett. 1999 Sep 17; 272(3):155-8. PMID: 10505604.
    Citations: 2     Fields:    Translation:HumansCells
  80. Postle BR, Locascio JJ, Corkin S, Growdon JH. The time course of spatial and object learning in Parkinson's disease. Neuropsychologia. 1997 Oct; 35(10):1413-22. PMID: 9347488.
    Citations: 14     Fields:    Translation:Humans
  81. Locascio JJ, Jennings PJ, Moore CI, Corkin S. Time series analysis in the time domain and resampling methods for studies of functional magnetic resonance brain imaging. Hum Brain Mapp. 1997; 5(3):168-93. PMID: 20408214.
    Citations: 15     Fields:    
  82. Growdon JH, Locascio JJ, Corkin S, Gomez-Isla T, Hyman BT. Apolipoprotein E genotype does not influence rates of cognitive decline in Alzheimer's disease. Neurology. 1996 Aug; 47(2):444-8. PMID: 8757018.
    Citations: 28     Fields:    Translation:Humans
  83. Gomez-Isla T, West HL, Rebeck GW, Harr SD, Growdon JH, Locascio JJ, Perls TT, Lipsitz LA, Hyman BT. Clinical and pathological correlates of apolipoprotein E epsilon 4 in Alzheimer's disease. Ann Neurol. 1996 Jan; 39(1):62-70. PMID: 8572669.
    Citations: 70     Fields:    Translation:HumansCells
  84. Locascio JJ, Growdon JH, Corkin S. Cognitive test performance in detecting, staging, and tracking Alzheimer's disease. Arch Neurol. 1995 Nov; 52(11):1087-99. PMID: 7487561.
    Citations: 32     Fields:    Translation:Humans
  85. Harris DT, LoCascio J, Acevedo A, Olson GB, Bard J, Boyse EA. Analysis of the hairless mouse as a model for the effects of aging on the immune system. Immunol Lett. 1993 Apr; 36(1):19-26. PMID: 8344713.
    Citations:    Fields:    Translation:AnimalsCells
  86. Locascio JJ, Lee J, Meltzer HY. Importance of adjusting for correlated concomitant variables in psychiatric research. Psychiatry Res. 1988 Mar; 23(3):311-27. PMID: 3387503.
    Citations: 2     Fields:    Translation:Humans
  87. Arora RC, Locascio JJ, Meltzer HY. 3H-imipramine binding in blood platelets of schizophrenic patients. Psychiatry Res. 1986 Nov; 19(3):215-24. PMID: 3797548.
    Citations:    Fields:    Translation:HumansCells
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Funded by the NIH/NCATS Clinical and Translational Science Award (CTSA) program, grant number UL1TR001102, and through institutional support from Harvard University, Harvard Medical School, Harvard T.H. Chan School of Public Health, Beth Israel Deaconess Medical Center, Boston Children's Hospital, Brigham and Women's Hospital, Massachusetts General Hospital and the Dana Farber Cancer Institute.