Harvard Catalyst Profiles

Contact, publication, and social network information about Harvard faculty and fellows.

Michael Costigan, Ph.D.

Co-Author

This page shows the publications co-authored by Michael Costigan and Clifford Woolf.
Connection Strength

5.606
  1. Analgesia by inhibiting tetrahydrobiopterin synthesis. Curr Opin Pharmacol. 2012 Feb; 12(1):92-9.
    View in: PubMed
    Score: 0.509
  2. Multiple chronic pain states are associated with a common amino acid-changing allele in KCNS1. Brain. 2010 Sep; 133(9):2519-27.
    View in: PubMed
    Score: 0.464
  3. Neuropathic pain: a maladaptive response of the nervous system to damage. Annu Rev Neurosci. 2009; 32:1-32.
    View in: PubMed
    Score: 0.415
  4. High basal expression and injury-induced down regulation of two regulator of G-protein signaling transcripts, RGS3 and RGS4 in primary sensory neurons. Mol Cell Neurosci. 2003 Sep; 24(1):106-16.
    View in: PubMed
    Score: 0.286
  5. Replicate high-density rat genome oligonucleotide microarrays reveal hundreds of regulated genes in the dorsal root ganglion after peripheral nerve injury. BMC Neurosci. 2002 Oct 25; 3:16.
    View in: PubMed
    Score: 0.270
  6. No DREAM, No pain. Closing the spinal gate. Cell. 2002 Feb 08; 108(3):297-300.
    View in: PubMed
    Score: 0.257
  7. Pain: molecular mechanisms. J Pain. 2000 Sep; 1(3 Suppl):35-44.
    View in: PubMed
    Score: 0.233
  8. Transcriptional and posttranslational plasticity and the generation of inflammatory pain. Proc Natl Acad Sci U S A. 1999 Jul 06; 96(14):7723-30.
    View in: PubMed
    Score: 0.215
  9. Diltiazem Promotes Regenerative Axon Growth. Mol Neurobiol. 2019 Jun; 56(6):3948-3957.
    View in: PubMed
    Score: 0.203
  10. Heat shock protein 27: developmental regulation and expression after peripheral nerve injury. J Neurosci. 1998 Aug 01; 18(15):5891-900.
    View in: PubMed
    Score: 0.201
  11. Mechanistic Differences in Neuropathic Pain Modalities Revealed by Correlating Behavior with Global Expression Profiling. Cell Rep. 2018 01 30; 22(5):1301-1312.
    View in: PubMed
    Score: 0.195
  12. Time-Resolved Fast Mammalian Behavior Reveals the Complexity of Protective Pain Responses. Cell Rep. 2017 07 05; 20(1):89-98.
    View in: PubMed
    Score: 0.187
  13. Robust Axonal Regeneration Occurs in the Injured CAST/Ei Mouse CNS. Neuron. 2016 May 04; 90(3):662.
    View in: PubMed
    Score: 0.172
  14. Reduction of Neuropathic and Inflammatory Pain through Inhibition of the Tetrahydrobiopterin Pathway. Neuron. 2015 Jun 17; 86(6):1393-406.
    View in: PubMed
    Score: 0.162
  15. Robust Axonal Regeneration Occurs in the Injured CAST/Ei Mouse CNS. Neuron. 2015 Jun 03; 86(5):1215-27.
    View in: PubMed
    Score: 0.161
  16. Accelerating axonal growth promotes motor recovery after peripheral nerve injury in mice. J Clin Invest. 2011 Nov; 121(11):4332-47.
    View in: PubMed
    Score: 0.125
  17. T-cell infiltration and signaling in the adult dorsal spinal cord is a major contributor to neuropathic pain-like hypersensitivity. J Neurosci. 2009 Nov 18; 29(46):14415-22.
    View in: PubMed
    Score: 0.110
  18. Ro5-4864 promotes neonatal motor neuron survival and nerve regeneration in adult rats. Eur J Neurosci. 2008 Feb; 27(4):937-46.
    View in: PubMed
    Score: 0.097
  19. Complement induction in spinal cord microglia results in anaphylatoxin C5a-mediated pain hypersensitivity. J Neurosci. 2007 Aug 08; 27(32):8699-708.
    View in: PubMed
    Score: 0.094
  20. GDNF selectively promotes regeneration of injury-primed sensory neurons in the lesioned spinal cord. Mol Cell Neurosci. 2007 Oct; 36(2):185-94.
    View in: PubMed
    Score: 0.094
  21. The voltage-gated sodium channel Na(v)1.9 is an effector of peripheral inflammatory pain hypersensitivity. J Neurosci. 2006 Dec 13; 26(50):12852-60.
    View in: PubMed
    Score: 0.090
  22. GTP cyclohydrolase and tetrahydrobiopterin regulate pain sensitivity and persistence. Nat Med. 2006 Nov; 12(11):1269-77.
    View in: PubMed
    Score: 0.089
  23. Exploiting microarrays to reveal differential gene expression in the nervous system. Genome Biol. 2003; 4(2):105.
    View in: PubMed
    Score: 0.069
  24. Developmental expression of the TTX-resistant voltage-gated sodium channels Nav1.8 (SNS) and Nav1.9 (SNS2) in primary sensory neurons. J Neurosci. 2001 Aug 15; 21(16):6077-85.
    View in: PubMed
    Score: 0.062
  25. Differential gene expression--how to find new analgesic targets. Curr Opin Investig Drugs. 2001 Mar; 2(3):396-8.
    View in: PubMed
    Score: 0.060
  26. Diversity of expression of the sensory neuron-specific TTX-resistant voltage-gated sodium ion channels SNS and SNS2. Mol Cell Neurosci. 2000 Apr; 15(4):331-42.
    View in: PubMed
    Score: 0.057
  27. Sepiapterin Reductase Inhibition Leading to Selective Reduction of Inflammatory Joint Pain in Mice and Increased Urinary Sepiapterin Levels in Humans and Mice. Arthritis Rheumatol. 2020 01; 72(1):57-66.
    View in: PubMed
    Score: 0.055
  28. A role for HSP27 in sensory neuron survival. J Neurosci. 1999 Oct 15; 19(20):8945-53.
    View in: PubMed
    Score: 0.055
  29. Neurotrophins: peripherally and centrally acting modulators of tactile stimulus-induced inflammatory pain hypersensitivity. Proc Natl Acad Sci U S A. 1999 Aug 03; 96(16):9385-90.
    View in: PubMed
    Score: 0.054
  30. Publisher Correction: The metabolite BH4 controls T cell proliferation in autoimmunity and cancer. Nature. 2019 Aug; 572(7769):E18.
    View in: PubMed
    Score: 0.054
  31. Two sodium channels contribute to the TTX-R sodium current in primary sensory neurons. Nat Neurosci. 1998 Dec; 1(8):653-5.
    View in: PubMed
    Score: 0.052
  32. The metabolite BH4 controls T cell proliferation in autoimmunity and cancer. Nature. 2018 11; 563(7732):564-568.
    View in: PubMed
    Score: 0.051
  33. Enhanced Neuronal Regeneration in the CAST/Ei Mouse Strain Is Linked to Expression of Differentiation Markers after Injury. Cell Rep. 2017 08 01; 20(5):1136-1147.
    View in: PubMed
    Score: 0.047
  34. A Systems-Level Analysis of the Peripheral Nerve Intrinsic Axonal Growth Program. Neuron. 2016 Mar 02; 89(5):956-70.
    View in: PubMed
    Score: 0.042
  35. The serine protease inhibitor SerpinA3N attenuates neuropathic pain by inhibiting T cell-derived leukocyte elastase. Nat Med. 2015 May; 21(5):518-23.
    View in: PubMed
    Score: 0.040
  36. Construction of a global pain systems network highlights phospholipid signaling as a regulator of heat nociception. PLoS Genet. 2012; 8(12):e1003071.
    View in: PubMed
    Score: 0.034
  37. Genetically determined P2X7 receptor pore formation regulates variability in chronic pain sensitivity. Nat Med. 2012 Mar 25; 18(4):595-9.
    View in: PubMed
    Score: 0.032
  38. The BMP coreceptor RGMb promotes while the endogenous BMP antagonist noggin reduces neurite outgrowth and peripheral nerve regeneration by modulating BMP signaling. J Neurosci. 2011 Dec 14; 31(50):18391-400.
    View in: PubMed
    Score: 0.032
  39. TrpA1 regulates thermal nociception in Drosophila. PLoS One. 2011; 6(8):e24343.
    View in: PubMed
    Score: 0.031
  40. A genome-wide Drosophila screen for heat nociception identifies a2d3 as an evolutionarily conserved pain gene. Cell. 2010 Nov 12; 143(4):628-38.
    View in: PubMed
    Score: 0.029
  41. TRPA1 contributes to cold hypersensitivity. J Neurosci. 2010 Nov 10; 30(45):15165-74.
    View in: PubMed
    Score: 0.029
  42. COX2 in CNS neural cells mediates mechanical inflammatory pain hypersensitivity in mice. J Clin Invest. 2009 Feb; 119(2):287-94.
    View in: PubMed
    Score: 0.026
  43. GCH1 haplotype determines vascular and plasma biopterin availability in coronary artery disease effects on vascular superoxide production and endothelial function. J Am Coll Cardiol. 2008 Jul 08; 52(2):158-65.
    View in: PubMed
    Score: 0.025
  44. Reliable screening for a pain-protective haplotype in the GTP cyclohydrolase 1 gene (GCH1) through the use of 3 or fewer single nucleotide polymorphisms. Clin Chem. 2007 Jun; 53(6):1010-5.
    View in: PubMed
    Score: 0.023
  45. Identification and characterization of a novel human vanilloid receptor-like protein, VRL-2. Physiol Genomics. 2001 Jan 19; 4(3):165-74.
    View in: PubMed
    Score: 0.015
Connection Strength
The connection strength for co-authors is the sum of the scores for each of their shared publications.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.
Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.