Harvard Catalyst Profiles

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Rajeev Indrajit Desai, Ph.D.

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research activities and funding
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
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  1. K01DA031231 (DESAI, RAJEEV INDRAJIT) Mar 1, 2012 - Feb 29, 2016
    NIH/NIDA
    Drug Abuse Methodology: Training and Interdisciplinary Application
    Role: Principal Investigator
  2. R21DA026548 (DESAI, RAJEEV INDRAJIT) Jun 20, 2009 - May 31, 2011
    NIH/NIDA
    Nicotinic Modulation of Methamphetamine's Behavioral and Neurochemical Effects
    Role: Principal Investigator

Bibliographic
selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Robble MA, Holloway IL, Ridener E, Webber CJ, Caine SB, Meloni E, Desai RI, Carlezon WA. Differential effects of nicotine and nicotine withdrawal on fear conditioning in male rats. Int J Neuropsychopharmacol. 2020 Apr 02. PMID: 32242615.
    Citations:    
  2. Withey SL, Doyle MR, Bergman J, Desai RI. Involvement of Nicotinic Receptor Subtypes in the Behavioral Effects of Nicotinic Drugs in Squirrel Monkeys. J Pharmacol Exp Ther. 2018 08; 366(2):397-409. PMID: 29784663.
    Citations:    Fields:    
  3. Fischer KD, Houston ACW, Desai RI, Doyle MR, Bergman J, Mian M, Mannix R, Sulzer DL, Choi SJ, Mosharov EV, Hodgson NW, Bechtholt A, Miczek KA, Rosenberg PA. Behavioral phenotyping and dopamine dynamics in mice with conditional deletion of the glutamate transporter GLT-1 in neurons: resistance to the acute locomotor effects of amphetamine. Psychopharmacology (Berl). 2018 05; 235(5):1371-1387. PMID: 29468294.
    Citations:    Fields:    
  4. Puhl MD, Desai RI, Takagi S, Presti KT, Doyle MR, Donahue RJ, Landino SM, Bergman J, Carlezon WA, Coyle JT. N-Methyl-d-aspartate receptor co-agonist availability affects behavioral and neurochemical responses to cocaine: insights into comorbid schizophrenia and substance abuse. Addict Biol. 2019 01; 24(1):40-50. PMID: 29168271.
    Citations:    Fields:    
  5. Slezak JM, Desai RI, Katz JL. Further delineation between typical and atypical dopamine uptake inhibitors: effects on food-maintained behavior and food consumption. Behav Pharmacol. 2017 02; 28(1):74-82. PMID: 27926573.
    Citations:    Fields:    Translation:Animals
  6. Desai RI, Sullivan KA, Kohut SJ, Bergman J. Influence of experimental history on nicotine self-administration in squirrel monkeys. Psychopharmacology (Berl). 2016 06; 233(12):2253-63. PMID: 27040402.
    Citations: 3     Fields:    Translation:Animals
  7. Desai RI, Doyle MR, Withey SL, Bergman J. Nicotinic effects of tobacco smoke constituents in nonhuman primates. Psychopharmacology (Berl). 2016 05; 233(10):1779-89. PMID: 26892379.
    Citations: 3     Fields:    Translation:Animals
  8. Desai RI, Bergman J. Nicotine-Targeting Nano-Vaccines for Smoking Cessation. Neuropsychopharmacology. 2016 Jan; 41(1):377-8. PMID: 26657956.
    Citations: 3     Fields:    Translation:HumansAnimals
  9. Desai RI, Bergman J. Effects of the Nanoparticle-Based Vaccine, SEL-068, on Nicotine Discrimination in Squirrel Monkeys. Neuropsychopharmacology. 2015 Aug; 40(9):2207-16. PMID: 25742871.
    Citations: 10     Fields:    Translation:AnimalsPHPublic Health
  10. Desai RI, Bergman J. Methamphetamine-like discriminative-stimulus effects of nicotinic agonists. J Pharmacol Exp Ther. 2014 Mar; 348(3):478-88. PMID: 24389640.
    Citations: 8     Fields:    Translation:Animals
  11. Desai RI, Grandy DK, Lupica CR, Katz JL. Pharmacological characterization of a dopamine transporter ligand that functions as a cocaine antagonist. J Pharmacol Exp Ther. 2014 Jan; 348(1):106-15. PMID: 24194528.
    Citations: 5     Fields:    Translation:Animals
  12. Desai RI, Thakur GA, Vemuri VK, Bajaj S, Makriyannis A, Bergman J. Analysis of tolerance and behavioral/physical dependence during chronic CB1 agonist treatment: effects of CB1 agonists, antagonists, and noncannabinoid drugs. J Pharmacol Exp Ther. 2013 Feb; 344(2):319-28. PMID: 23197773.
    Citations: 7     Fields:    Translation:Animals
  13. Desai RI, Bergman J. Drug discrimination in methamphetamine-trained rats: effects of cholinergic nicotinic compounds. J Pharmacol Exp Ther. 2010 Dec; 335(3):807-16. PMID: 20847037.
    Citations: 22     Fields:    Translation:Animals
  14. Desai RI, Paronis CA, Martin J, Desai R, Bergman J. Monoaminergic psychomotor stimulants: discriminative stimulus effects and dopamine efflux. J Pharmacol Exp Ther. 2010 Jun; 333(3):834-43. PMID: 20190012.
    Citations: 18     Fields:    Translation:AnimalsCells
  15. Terry P, Doumas M, Desai RI, Wing AM. Dissociations between motor timing, motor coordination, and time perception after the administration of alcohol or caffeine. Psychopharmacology (Berl). 2009 Mar; 202(4):719-29. PMID: 18846366.
    Citations: 3     Fields:    Translation:Humans
  16. Desai RI, Neumeyer JL, Bergman J, Paronis CA. Pharmacological characterization of the effects of dopamine D(1) agonists on eye blinking in rats. Behav Pharmacol. 2007 Dec; 18(8):745-54. PMID: 17989512.
    Citations: 2     Fields:    Translation:Animals
  17. Loland CJ, Desai RI, Zou MF, Cao J, Grundt P, Gerstbrein K, Sitte HH, Newman AH, Katz JL, Gether U. Relationship between conformational changes in the dopamine transporter and cocaine-like subjective effects of uptake inhibitors. Mol Pharmacol. 2008 Mar; 73(3):813-23. PMID: 17978168.
    Citations: 66     Fields:    Translation:AnimalsCells
  18. Desai RI, Neumeyer JL, Paronis CA, Nguyen P, Bergman J. Behavioral effects of the R-(+)- and S-(-)-enantiomers of the dopamine D(1)-like partial receptor agonist SKF 83959 in monkeys. Eur J Pharmacol. 2007 Mar 08; 558(1-3):98-106. PMID: 17207791.
    Citations: 2     Fields:    Translation:Animals
  19. Zou MF, Cao J, Kopajtic T, Desai RI, Katz JL, Newman AH. Structure-activity relationship studies on a novel series of (S)-2beta-substituted 3alpha-[bis(4-fluoro- or 4-chlorophenyl)methoxy]tropane analogues for in vivo investigation. J Med Chem. 2006 Oct 19; 49(21):6391-9. PMID: 17034144.
    Citations: 5     Fields:    Translation:AnimalsCells
  20. Desai RI, Neumeyer JL, Nguyen P, Bergman J. Behavioral Effects of the R-(+)- and S-(-) Enantiomers of the D1-like partial agonist SKF 83959 in squirrel monkeys. European Journal of Pharmacology, Submitted September. 2006.
  21. Desai RI, Newman AH, Katz JL. Antagonism of cocaine’s stimulant effects by a dopamine transporter ligand, JHW 007. Presented at the European Behavioral Pharmacology Society, Barcelona, Spain, Sepember 9-12, Behavioral Pharmacology. 2005; 16(1):B39.
  22. Desai RI, Terry P, Katz JL. A comparison of the locomotor stimulant effects of D1-like receptor agonists in mice. Pharmacol Biochem Behav. 2005 Aug; 81(4):843-8. PMID: 16000217.
    Citations: 19     Fields:    Translation:AnimalsCells
  23. Desai RI, Kopajtic TA, French D, Newman AH, Katz JL. Relationship between in vivo occupancy at the dopamine transporter and behavioral effects of cocaine, GBR 12909 [1-{2-[bis-(4-fluorophenyl)methoxy]ethyl}-4-(3-phenylpropyl)piperazine], and benztropine analogs. J Pharmacol Exp Ther. 2005 Oct; 315(1):397-404. PMID: 16014753.
    Citations: 25     Fields:    Translation:Animals
  24. Desai RI, Kopajtic TA, Koffarnus M, Newman AH, Katz JL. Identification of a dopamine transporter ligand that blocks the stimulant effects of cocaine. J Neurosci. 2005 Feb 23; 25(8):1889-93. PMID: 15728828.
    Citations: 43     Fields:    Translation:Animals
  25. Desai RI, Katz JL. Relationship between locomotor stimulant effects of dopamine D1-like receptor agonists and their efficacy in stimulating adenylyl cyclase. Presented at the Society for Neuroscience 34th Annual Meeting, San Diego, USA, October 23-27, Washington DC: Society for Neuroscience. 2004; Program No. 122.19.
  26. Desai RI, Katz JL. Discriminative stimulus effects of SKF 82958. Presented at the Experimental Biology 2004 Meeting, Washington DC, USA, April 17-21,. 2004; Program 160.3(Serial No. 160).
  27. Desai RI, M-F Zou M-F, Kopajtic TA, Newman AH, Katz JL. Cocaine-like discriminative stimulus (DS) effects of novel benztropine (BZT) analogs that have low affinity for muscarinic M1 receptors. Presented at the Society for Neuroscience 33rd Annual Meeting, New Orleans, USA, November 8-12, Washington DC: Society for Neuroscience. 2003.
  28. Desai RI, Kopajtic TA, Newman AH, Katz JL. Relationship between in vivo occupancy at the dopamine transporter and behavioral effects of cocaine and analogs of benztropine (BZT). Presented at the European Behavioural Pharmacology Society, Antwerp, Belgium, September 6-9, Behavioral Pharmacology. 2003; 14(1):S54.
  29. Desai RI, Terry P, Katz JL. Comparison of the discriminative-stimulus effects of SKF 38393 with those of other dopamine receptor agonists. Behav Pharmacol. 2003 May; 14(3):223-8. PMID: 12799524.
    Citations: 2     Fields:    Translation:HumansAnimals
  30. Desai RI, Kopajtic TA, Newman AH, Katz JL. In vivo binding and behavioral effects of benztropine analogs. Presented at the Experimental Biology 2003 Meeting, San Diego, USA, April 11-15. 2003; Program 140.2(Serial No. 140).
  31. Desai RI, Barber DJ, Terry P. Dopaminergic and cholinergic involvement in the discriminative stimulus effects of nicotine and cocaine in rats. Psychopharmacology (Berl). 2003 Jun; 167(4):335-43. PMID: 12684733.
    Citations: 30     Fields:    Translation:Animals
  32. Desai RI, Terry P. Evidence of cross-tolerance between behavioural effects of nicotine and cocaine in mice. Psychopharmacology (Berl). 2003 Mar; 166(2):111-9. PMID: 12545328.
    Citations: 9     Fields:    Translation:Animals
  33. Desai RI, Terry P. Evidence of cross-tolerance between selective behavioural effects of nicotine and cocaine in mice. Presented at the joint meeting of European Behavioural Pharmacology Society and British Association of Psychopharmacology, Brighton, UK, September 19-21,. 2002; 13(5 & 6 ):481.
  34. Desai RI, Terry P, Katz JL, Schindler CW. Comparison of the discriminative stimulus effects of SKF 38393 with those of other direct dopamine receptor agonists. Presented at the Society for Neuroscience 32nd Annual Meeting, Orlando, USA, November 2-7, Washington, DC: Society for Neuroscience. 2002; Program No. 782.13.
  35. Rajeev I. Desai. Similarites and Difference Between the Behavioral Effects of Nicotine and Cocaine: An Investigation Using Drug Discrimination and Analysis of Motor Behaviour. 2001.
  36. Desai RI, Barber DJ, Terry P. Behavioural interactions between cocaine and nicotine: A drug discrimination analysis. Presented at the joint meeting of European Behavioural Pharmacology Society and European Brain and Behaviour Society, Marseille, France, September 8-12, Behavioral Pharmacology. 2001; 12(1):S28.
  37. Desai RI, Barber DJ, Terry P. Chronic nicotine treatment alters the responsiveness of specific behaviours to a challenge dose of cocaine. Presented at the British Association for Psychopharmacology, Cambridge, UK, July 16-19, Journal of Psychopharmacology. 2000; 14(3):A20.
  38. Desai RI, Barber DJ, Terry P. The contributions of dopaminergic and nicotinic cholinergic mechanisms to the discriminative stimulus effects of cocaine and nicotine. Presented at the British Association for Psychopharmacology, Cambridge, UK, July 16-19, Journal of Psychopharmacology. 2000; 14(3):A20.
  39. Desai RI, Barber DJ, Terry P. Asymmetric generalization between the discriminative stimulus effects of nicotine and cocaine. Behav Pharmacol. 1999 Nov; 10(6-7):647-56. PMID: 10780506.
    Citations: 17     Fields:    Translation:AnimalsCells
  40. Desai RI, Barber DJ, Terry P. Absence of interactive effects between nicotine and cocaine on various unconditioned motor behaviours. Presented at the joint meeting of Behavioral Pharmacology Society and the European Behavioural Pharmacology Society, Boston, USA, September 1-5, Behavioral Pharmacology. 1999; 10(1):S24.
  41. Desai RI, Barber DJ, Terry P. Asymmetrical generalization between the discriminative stimulus effects of nicotine and cocaine. Presented at the European Behavioural Pharmacology Society, Brno, Czech Republic, September 2-6, Behavioral Pharmacology. 1998; 9(1):S31.
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.