Harvard Catalyst Profiles

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A. Thomas Look, M.D.

Co-Author

This page shows the publications co-authored by A. Look and Shuning He.
Connection Strength

3.190
  1. Synergistic melanoma cell death mediated by inhibition of both MCL1 and BCL2 in high-risk tumors driven by NF1/PTEN loss. Oncogene. 2021 Sep; 40(38):5718-5729.
    View in: PubMed
    Score: 0.978
  2. Synergy between loss of NF1 and overexpression of MYCN in neuroblastoma is mediated by the GAP-related domain. Elife. 2016 04 27; 5.
    View in: PubMed
    Score: 0.679
  3. The MCL1-specific inhibitor S63845 acts synergistically with venetoclax/ABT-199 to induce apoptosis in T-cell acute lymphoblastic leukemia cells. Leukemia. 2019 01; 33(1):262-266.
    View in: PubMed
    Score: 0.198
  4. JDP2: An oncogenic bZIP transcription factor in T cell acute lymphoblastic leukemia. J Exp Med. 2018 07 02; 215(7):1929-1945.
    View in: PubMed
    Score: 0.197
  5. MYC Drives a Subset of High-Risk Pediatric Neuroblastomas and Is Activated through Mechanisms Including Enhancer Hijacking and Focal Enhancer Amplification. Cancer Discov. 2018 03; 8(3):320-335.
    View in: PubMed
    Score: 0.191
  6. LMO1 Synergizes with MYCN to Promote Neuroblastoma Initiation and Metastasis. Cancer Cell. 2017 09 11; 32(3):310-323.e5.
    View in: PubMed
    Score: 0.186
  7. Overexpression of PDGFRA cooperates with loss of NF1 and p53 to accelerate the molecular pathogenesis of malignant peripheral nerve sheath tumors. Oncogene. 2017 02 23; 36(8):1058-1068.
    View in: PubMed
    Score: 0.173
  8. Malignant Peripheral Nerve Sheath Tumors. Adv Exp Med Biol. 2016; 916:495-530.
    View in: PubMed
    Score: 0.166
  9. A zebrafish model of myelodysplastic syndrome produced through tet2 genomic editing. Mol Cell Biol. 2015 Mar; 35(5):789-804.
    View in: PubMed
    Score: 0.154
  10. Zebrafish neurofibromatosis type 1 genes have redundant functions in tumorigenesis and embryonic development. Dis Model Mech. 2012 Nov; 5(6):881-94.
    View in: PubMed
    Score: 0.130
  11. Selective gene dependencies in MYCN-amplified neuroblastoma include the core transcriptional regulatory circuitry. Nat Genet. 2018 09; 50(9):1240-1246.
    View in: PubMed
    Score: 0.050
  12. Critical Role for GAB2 in Neuroblastoma Pathogenesis through the Promotion of SHP2/MYCN Cooperation. Cell Rep. 2017 03 21; 18(12):2932-2942.
    View in: PubMed
    Score: 0.045
  13. Imaging tumour cell heterogeneity following cell transplantation into optically clear immune-deficient zebrafish. Nat Commun. 2016 Jan 21; 7:10358.
    View in: PubMed
    Score: 0.042
Connection Strength
The connection strength for co-authors is the sum of the scores for each of their shared publications.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.
Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.