Harvard Catalyst Profiles

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Kiyoshi Itagaki, Ph.D.

Concepts

This page shows the publications Kiyoshi Itagaki has written about Humans.
Connection Strength

0.097
  1. Formyl Peptide Receptor-1 Blockade Prevents Receptor Regulation by Mitochondrial Danger-Associated Molecular Patterns and Preserves Neutrophil Function After Trauma. Crit Care Med. 2020 02; 48(2):e123-e132.
    View in: PubMed
    Score: 0.010
  2. A subset of five human mitochondrial formyl peptides mimics bacterial peptides and functionally deactivates human neutrophils. J Trauma Acute Care Surg. 2018 11; 85(5):936-943.
    View in: PubMed
    Score: 0.010
  3. Mitochondrial DNA released by trauma induces neutrophil extracellular traps. PLoS One. 2015; 10(3):e0120549.
    View in: PubMed
    Score: 0.007
  4. Mitochondrial DAMPs increase endothelial permeability through neutrophil dependent and independent pathways. PLoS One. 2013; 8(3):e59989.
    View in: PubMed
    Score: 0.007
  5. Bacterial DNA induces pulmonary damage via TLR-9 through cross-talk with neutrophils. Shock. 2011 Dec; 36(6):548-52.
    View in: PubMed
    Score: 0.006
  6. Mitochondrial damage associated molecular patterns from femoral reamings activate neutrophils through formyl peptide receptors and P44/42 MAP kinase. J Orthop Trauma. 2010 Sep; 24(9):534-8.
    View in: PubMed
    Score: 0.005
  7. Sphingosine kinase inhibition alleviates endothelial permeability induced by thrombin and activated neutrophils. Shock. 2010 Apr; 33(4):381-6.
    View in: PubMed
    Score: 0.005
  8. Sphingosine 1-phosphate has dual functions in the regulation of endothelial cell permeability and Ca2+ metabolism. J Pharmacol Exp Ther. 2007 Oct; 323(1):186-91.
    View in: PubMed
    Score: 0.004
  9. Non-specific effects of 4-chloro-m-cresol may cause calcium flux and respiratory burst in human neutrophils. Biochem Biophys Res Commun. 2005 Nov 04; 336(4):1087-95.
    View in: PubMed
    Score: 0.004
  10. Lysophosphatidic acid triggers calcium entry through a non-store-operated pathway in human neutrophils. J Leukoc Biol. 2005 Feb; 77(2):181-9.
    View in: PubMed
    Score: 0.004
  11. Cytoskeletal reorganization internalizes multiple transient receptor potential channels and blocks calcium entry into human neutrophils. J Immunol. 2004 Jan 01; 172(1):601-7.
    View in: PubMed
    Score: 0.003
  12. Sphingosine 1-phosphate, a diffusible calcium influx factor mediating store-operated calcium entry. J Biol Chem. 2003 Jul 25; 278(30):27540-7.
    View in: PubMed
    Score: 0.003
  13. Store-operated calcium entry in human neutrophils reflects multiple contributions from independently regulated pathways. J Immunol. 2002 Apr 15; 168(8):4063-9.
    View in: PubMed
    Score: 0.003
  14. Monocyte exocytosis of mitochondrial danger-associated molecular patterns in sepsis suppresses neutrophil chemotaxis. J Trauma Acute Care Surg. 2021 01 01; 90(1):46-53.
    View in: PubMed
    Score: 0.003
  15. Multiplexed Plasma Immune Mediator Signatures Can Differentiate Sepsis From NonInfective SIRS: American Surgical Association 2020 Annual Meeting Paper. Ann Surg. 2020 10; 272(4):604-610.
    View in: PubMed
    Score: 0.003
  16. Mitochondrial DNA in the tumour microenvironment activates neutrophils and is associated with worse outcomes in patients with advanced epithelial ovarian cancer. Br J Cancer. 2019 01; 120(2):207-217.
    View in: PubMed
    Score: 0.002
  17. Scavenging Circulating Mitochondrial DNA as a Potential Therapeutic Option for Multiple Organ Dysfunction in Trauma Hemorrhage. Front Immunol. 2018; 9:891.
    View in: PubMed
    Score: 0.002
  18. Mitochondrial DAMPs Are Released During Cardiopulmonary Bypass Surgery and Are Associated With Postoperative Atrial Fibrillation. Heart Lung Circ. 2018 Jan; 27(1):122-129.
    View in: PubMed
    Score: 0.002
  19. Mitochondrial damage-associated molecular patterns from fractures suppress pulmonary immune responses via formyl peptide receptors 1 and 2. J Trauma Acute Care Surg. 2015 Feb; 78(2):272-9; discussion 279-81.
    View in: PubMed
    Score: 0.002
  20. NADPH oxidase and Nrf2 regulate gastric aspiration-induced inflammation and acute lung injury. J Immunol. 2013 Feb 15; 190(4):1714-24.
    View in: PubMed
    Score: 0.002
  21. ETS-related gene (ERG) controls endothelial cell permeability via transcriptional regulation of the claudin 5 (CLDN5) gene. J Biol Chem. 2012 Feb 24; 287(9):6582-91.
    View in: PubMed
    Score: 0.002
  22. Mitochondrial DNA is released by shock and activates neutrophils via p38 map kinase. Shock. 2010 Jul; 34(1):55-9.
    View in: PubMed
    Score: 0.001
  23. Mitochondrial peptides are potent immune activators that activate human neutrophils via FPR-1. J Trauma. 2010 Jun; 68(6):1328-32; discussion 1332-4.
    View in: PubMed
    Score: 0.001
  24. Circulating mitochondrial DAMPs cause inflammatory responses to injury. Nature. 2010 Mar 04; 464(7285):104-7.
    View in: PubMed
    Score: 0.001
  25. Lymph from a primate baboon trauma hemorrhagic shock model activates human neutrophils. Shock. 2006 May; 25(5):460-3.
    View in: PubMed
    Score: 0.001
  26. Prospective study of neutrophil chemokine responses in trauma patients at risk for pneumonia. Am J Respir Crit Care Med. 2005 Apr 01; 171(7):753-9.
    View in: PubMed
    Score: 0.001
  27. Inflammatory chemoreceptor cross-talk suppresses leukotriene B4 receptor 1-mediated neutrophil calcium mobilization and chemotaxis after trauma. J Immunol. 2003 Aug 15; 171(4):2066-73.
    View in: PubMed
    Score: 0.001
  28. Resolution of the identity of the Ca2(+)-antagonist receptor in skeletal muscle. Trends Pharmacol Sci. 1988 Nov; 9(11):398-402.
    View in: PubMed
    Score: 0.000
Connection Strength

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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.