Harvard Catalyst Profiles

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Philip K. Demokritou, Ph.D.

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Research
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. U24ES026946 (DEMOKRITOU, PHILIP) Jul 15, 2016 - Jun 30, 2021
    NIH/NIEHS
    Engineered Nanomaterial Synthesis, Characterization and Method Development Center for Nano-safety Research
    Role: Principal Investigator
  2. R21AI119481 (DEMOKRITOU, PHILIP) Jun 15, 2015 - May 31, 2017
    NIH/NIAID
    Inactivation of ambient virues using Engineered Water Nanostructures
    Role: Principal Investigator

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Yang Q, Keerthisinghe TP, Tan TRJ, Cao X, Setyawati MI, DeLoid G, Ng KW, Loo SCJ, Demokritou P, Fang M. A high-throughput method to characterize the gut bacteria growth upon engineered nanomaterial treatment. Environ Sci Nano. 2020 Oct 01; 7(10):3155-3166. PMID: 33101690.
    Citations:    
  2. Coyle JP, Derk RC, Kornberg TG, Singh D, Jensen J, Friend S, Mercer R, Stueckle TA, Demokritou P, Rojanasakul Y, Rojanasakul LW. Carbon nanotube filler enhances incinerated thermoplastics-induced cytotoxicity and metabolic disruption in vitro. Part Fibre Toxicol. 2020 08 12; 17(1):40. PMID: 32787867.
    Citations:    Fields:    
  3. Wu Z, Shi P, Lim HK, Ma Y, Setyawati MI, Bitounis D, Demokritou P, Ng KW, Tay CY. Inflammation Increases Susceptibility of Human Small Airway Epithelial Cells to Pneumonic Nanotoxicity. Small. 2020 May; 16(21):e2000963. PMID: 32338442.
    Citations:    Fields:    
  4. Parviz D, Bitounis D, Demokritou P, Strano M. Engineering Two-dimensional Nanomaterials to Enable Structure-Activity Relationship Studies in Nanosafety Research. NanoImpact. 2020 Apr; 18. PMID: 32617436.
    Citations:    
  5. O'Connor BB, Grevesse T, Zimmerman JF, Ardoña HAM, Jimenez JA, Bitounis D, Demokritou P, Parker KK. Human brain microvascular endothelial cell pairs model tissue-level blood-brain barrier function. Integr Biol (Camb). 2020 04 14; 12(3):64-79. PMID: 32195539.
    Citations:    Fields:    
  6. Bitounis D, Parviz D, Cao X, Amadei CA, Vecitis CD, Sunderland EM, Thrall BD, Fang M, Strano MS, Demokritou P. Synthesis and Physicochemical Transformations of Size-Sorted Graphene Oxide during Simulated Digestion and Its Toxicological Assessment against an In Vitro Model of the Human Intestinal Epithelium. Small. 2020 May; 16(21):e1907640. PMID: 32196921.
    Citations:    Fields:    
  7. Heller DA, Jena PV, Pasquali M, Kostarelos K, Delogu LG, Meidl RE, Rotkin SV, Scheinberg DA, Schwartz RE, Terrones M, Wang Y, Bianco A, Boghossian AA, Cambré S, Cognet L, Corrie SR, Demokritou P, Giordani S, Hertel T, Ignatova T, Islam MF, Iverson NM, Jagota A, Janas D, Kono J, Kruss S, Landry MP, Li Y, Martel R, Maruyama S, Naumov AV, Prato M, Quinn SJ, Roxbury D, Strano MS, Tour JM, Weisman RB, Wenseleers W, Yudasaka M. Banning carbon nanotubes would be scientifically unjustified and damaging to innovation. Nat Nanotechnol. 2020 03; 15(3):164-166. PMID: 32157238.
    Citations: 1     Fields:    
  8. Khare S, DeLoid GM, Molina RM, Gokulan K, Couvillion SP, Bloodsworth KJ, Eder EK, Wong AR, Hoyt DW, Bramer LM, Metz TO, Thrall BD, Brain JD, Demokritou P. Effects of ingested nanocellulose on intestinal microbiota and homeostasis in Wistar Han rats. NanoImpact. 2020 Apr; 18. PMID: 32190784.
    Citations:    
  9. Setyawati MI, Singh D, Krishnan SPR, Huang X, Wang M, Jia S, Goh BHR, Ho CG, Yusoff R, Kathawala MH, Poh TY, Ali NABM, Chotirmall SH, Aitken RJ, Riediker M, Christiani DC, Fang M, Bello D, Demokritou P, Ng KW. Occupational Inhalation Exposures to Nanoparticles at Six Singapore Printing Centers. Environ Sci Technol. 2020 02 18; 54(4):2389-2400. PMID: 31967798.
    Citations:    Fields:    Translation:PHPublic Health
  10. Carll AP, Salatini R, Pirela SV, Wang Y, Xie Z, Lorkiewicz P, Naeem N, Qian Y, Castranova V, Godleski JJ, Demokritou P. Inhalation of printer-emitted particles impairs cardiac conduction, hemodynamics, and autonomic regulation and induces arrhythmia and electrical remodeling in rats. Part Fibre Toxicol. 2020 01 29; 17(1):7. PMID: 31996220.
    Citations: 1     Fields:    
  11. Duan Y, Coreas R, Liu Y, Bitounis D, Zhang Z, Parviz D, Strano M, Demokritou P, Zhong W. Prediction of protein corona on nanomaterials by machine learning using novel descriptors. NanoImpact. 2020 Jan; 17. PMID: 32104746.
    Citations: 1     
  12. Dong J, Carpinone PL, Pyrgiotakis G, Demokritou P, Moudgil BM. Synthesis of Precision Gold Nanoparticles Using Turkevich Method. Kona. 2020 Jan 10; 37:224-232. PMID: 32153313.
    Citations: 3     
  13. Cao X, Zhang T, DeLoid GM, Gaffrey MJ, Weitz KK, Thrall BD, Qian WJ, Demokritou P. Evaluation of the cytotoxic and cellular proteome impacts of food-grade TiO2 (E171) using simulated gastrointestinal digestions and a tri-culture small intestinal epithelial model. NanoImpact. 2020 Jan; 17. PMID: 32133427.
    Citations: 1     
  14. Guo Z, Cao X, DeLoid GM, Sampathkumar K, Ng KW, Loo SCJ, Demokritou P. Physicochemical and Morphological Transformations of Chitosan Nanoparticles across the Gastrointestinal Tract and Cellular Toxicity in an In Vitro Model of the Small Intestinal Epithelium. J Agric Food Chem. 2020 Jan 08; 68(1):358-368. PMID: 31815446.
    Citations:    Fields:    Translation:HumansCells
  15. Guo NL, Poh TY, Pirela S, Farcas MT, Chotirmall SH, Tham WK, Adav SS, Ye Q, Wei Y, Shen S, Christiani DC, Ng KW, Thomas T, Qian Y, Demokritou P. Integrated Transcriptomics, Metabolomics, and Lipidomics Profiling in Rat Lung, Blood, and Serum for Assessment of Laser Printer-Emitted Nanoparticle Inhalation Exposure-Induced Disease Risks. Int J Mol Sci. 2019 Dec 16; 20(24). PMID: 31888290.
    Citations: 1     Fields:    Translation:AnimalsCellsPHPublic Health
  16. Kim S, Gates B, Leonard BC, Gragg M, Pinkerton KE, Winkle LV, Murphy CJ, Pyrgiotakis G, Zhang Z, Demokritou P, Thomasy SM. Engineered metal oxide nanomaterials inhibit corneal epithelial wound healing in vitro and in vivo. NanoImpact. 2020 Jan; 17. PMID: 32154443.
    Citations:    
  17. Kornberg TG, Stueckle TA, Coyle J, Derk R, Demokritou P, Rojanasakul Y, Rojanasakul LW. Iron Oxide Nanoparticle-Induced Neoplastic-Like Cell Transformation in Vitro Is Reduced with a Protective Amorphous Silica Coating. Chem Res Toxicol. 2019 12 16; 32(12):2382-2397. PMID: 31657553.
    Citations:    Fields:    Translation:HumansCells
  18. Rubio L, Pyrgiotakis G, Beltran-Huarac J, Zhang Y, Gaurav J, Deloid G, Spyrogianni A, Sarosiek KA, Bello D, Demokritou P. Safer-by-design flame-sprayed silicon dioxide nanoparticles: the role of silanol content on ROS generation, surface activity and cytotoxicity. Part Fibre Toxicol. 2019 10 29; 16(1):40. PMID: 31665028.
    Citations: 5     Fields:    Translation:AnimalsCells
  19. Eweje F, Ardoña HAM, Zimmerman JF, O'Connor BB, Ahn S, Grevesse T, Rivera KN, Bitounis D, Demokritou P, Parker KK. Quantifying the effects of engineered nanomaterials on endothelial cell architecture and vascular barrier integrity using a cell pair model. Nanoscale. 2019 Oct 03; 11(38):17878-17893. PMID: 31553035.
    Citations: 2     Fields:    Translation:HumansCells
  20. Tsuda A, Donaghey TC, Konduru NV, Pyrgiotakis G, Van Winkle LS, Zhang Z, Edwards P, Bustamante JM, Brain JD, Demokritou P. Age-Dependent Translocation of Gold Nanoparticles across the Air-Blood Barrier. ACS Nano. 2019 09 24; 13(9):10095-10102. PMID: 31397554.
    Citations:    Fields:    Translation:Animals
  21. Cao X, DeLoid GM, Bitounis D, De La Torre-Roche R, White JC, Zhang Z, Ho CG, Ng KW, Eitzer BD, Demokritou P. Co-exposure to the food additives SiO2 (E551) or TiO2 (E171) and the pesticide boscalid increases cytotoxicity and bioavailability of the pesticide in a tri-culture small intestinal epithelium model: Potential health implications. Environ Sci Nano. 2019 Sep 01; 6(9):2786-2800. PMID: 32133147.
    Citations: 6     
  22. Sampathkumar K, Riyajan S, Tan CK, Demokritou P, Chudapongse N, Loo SCJ. Small-Intestine-Specific Delivery of Antidiabetic Extracts from Withania coagulans Using Polysaccharide-Based Enteric-Coated Nanoparticles. ACS Omega. 2019 Jul 31; 4(7):12049-12057. PMID: 31460318.
    Citations: 2     
  23. DeLoid GM, Cao X, Molina RM, Silva DI, Bhattacharya K, Ng KW, Loo SCJ, Brain JD, Demokritou P. Toxicological effects of ingested nanocellulose in in vitro intestinal epithelium and in vivo rat models. Environ Sci Nano. 2019 Jul 01; 6(7):2105-2115. PMID: 32133146.
    Citations: 5     
  24. Zhang Y, Demokritou P, Ryan DK, Bello D. Comprehensive Assessment of Short-Lived ROS and H2O2 in Laser Printer Emissions: Assessing the Relative Contribution of Metal Oxides and Organic Constituents. Environ Sci Technol. 2019 07 02; 53(13):7574-7583. PMID: 31120250.
    Citations: 1     Fields:    Translation:Humans
  25. Bitounis D, Pyrgiotakis G, Bousfield D, Demokritou P. Dispersion preparation, characterization, and dosimetric analysis of cellulose nano-fibrils and nano-crystals: Implications for cellular toxicological studies. NanoImpact. 2019 Mar; 15. PMID: 32133424.
    Citations: 1     
  26. Salari M, Bitounis D, Bhattacharya K, Pyrgiotakis G, Zhang Z, Purington E, Gramlich W, Grondin Y, Rogers R, Bousfield D, Demokritou P. Development & Characterization of Fluorescently Tagged Nanocellulose for Nanotoxicological Studies. Environ Sci Nano. 2019 May 01; 6(5):1516-1526. PMID: 31844523.
    Citations: 2     
  27. Vaze N, Pyrgiotakis G, McDevitt J, Mena L, Melo A, Bedugnis A, Kobzik L, Eleftheriadou M, Demokritou P. Inactivation of common hospital acquired pathogens on surfaces and in air utilizing engineered water nanostructures (EWNS) based nano-sanitizers. Nanomedicine. 2019 06; 18:234-242. PMID: 30904585.
    Citations: 2     Fields:    
  28. Zimmerman JF, Ardoña HAM, Pyrgiotakis G, Dong J, Moudgil B, Demokritou P, Parker KK. Scatter Enhanced Phase Contrast Microscopy for Discriminating Mechanisms of Active Nanoparticle Transport in Living Cells. . 2019 02 13; 19(2):793-804. PMID: 30616354.
    Citations: 6     Translation:HumansCells
  29. Zhang Z, Zhang R, Xiao H, Bhattacharya K, Bitounis D, Demokritou P, McClements DJ. Development of a standardized food model for studying the impact of food matrix effects on the gastrointestinal fate and toxicity of ingested nanomaterials. NanoImpact. 2019 Jan; 13:13-25. PMID: 31093583.
    Citations: 10     
  30. Vaze N, Pyrgiotakis G, Mena L, Baumann R, Demokritou A, Ericsson M, Zhang Y, Bello D, Eleftheriadou M, Demokritou P. A nano-carrier platform for the targeted delivery of nature-inspired antimicrobials using Engineered Water Nanostructures for food safety applications. Food Control. 2019 Feb; 96:365-374. PMID: 32132770.
    Citations: 1     
  31. Sohal IS, Cho YK, O'Fallon KS, Gaines P, Demokritou P, Bello D. Dissolution Behavior and Biodurability of Ingested Engineered Nanomaterials in the Gastrointestinal Environment. ACS Nano. 2018 08 28; 12(8):8115-8128. PMID: 30021067.
    Citations: 8     Fields:    Translation:Humans
  32. Sohal IS, O'Fallon KS, Gaines P, Demokritou P, Bello D. Ingested engineered nanomaterials: state of science in nanotoxicity testing and future research needs. Part Fibre Toxicol. 2018 07 03; 15(1):29. PMID: 29970114.
    Citations: 17     Fields:    Translation:HumansAnimalsPHPublic Health
  33. Setyawati MI, Sevencan C, Bay BH, Xie J, Zhang Y, Demokritou P, Leong DT. Nano-TiO2 Drives Epithelial-Mesenchymal Transition in Intestinal Epithelial Cancer Cells. Small. 2018 07; 14(30):e1800922. PMID: 29968352.
    Citations: 9     Fields:    Translation:HumansCells
  34. DeLoid GM, Sohal IS, Lorente LR, Molina RM, Pyrgiotakis G, Stevanovic A, Zhang R, McClements DJ, Geitner NK, Bousfield DW, Ng KW, Loo SCJ, Bell DC, Brain J, Demokritou P. Reducing Intestinal Digestion and Absorption of Fat Using a Nature-Derived Biopolymer: Interference of Triglyceride Hydrolysis by Nanocellulose. ACS Nano. 2018 07 24; 12(7):6469-6479. PMID: 29874029.
    Citations: 13     Fields:    Translation:HumansAnimalsCells
  35. Lee JY, Wang H, Pyrgiotakis G, DeLoid GM, Zhang Z, Beltran-Huarac J, Demokritou P, Zhong W. Analysis of lipid adsorption on nanoparticles by nanoflow liquid chromatography-tandem mass spectrometry. Anal Bioanal Chem. 2018 Sep; 410(24):6155-6164. PMID: 29845324.
    Citations: 8     Fields:    Translation:HumansCells
  36. Konduru NV, Damiani F, Stoilova-McPhie S, Tresback JS, Pyrgiotakis G, Donaghey TC, Demokritou P, Brain JD, Molina RM. Nanoparticle Wettability Influences Nanoparticle-Phospholipid Interactions. Langmuir. 2018 06 05; 34(22):6454-6461. PMID: 29754486.
    Citations: 1     Fields:    Translation:Animals
  37. Ahn S, Ardoña HAM, Lind JU, Eweje F, Kim SL, Gonzalez GM, Liu Q, Zimmerman JF, Pyrgiotakis G, Zhang Z, Beltran-Huarac J, Carpinone P, Moudgil BM, Demokritou P, Parker KK. Mussel-inspired 3D fiber scaffolds for heart-on-a-chip toxicity studies of engineered nanomaterials. Anal Bioanal Chem. 2018 Sep; 410(24):6141-6154. PMID: 29744562.
    Citations: 12     Fields:    Translation:AnimalsCells
  38. Zhao J, Nelson J, Dada O, Pyrgiotakis G, Kavouras IG, Demokritou P. Assessing electronic cigarette emissions: linking physico-chemical properties to product brand, e-liquid flavoring additives, operational voltage and user puffing patterns. Inhal Toxicol. 2018 02; 30(2):78-88. PMID: 29564955.
    Citations: 11     Fields:    Translation:Animals
  39. Pyrgiotakis G, Luu W, Zhang Z, Vaze N, DeLoid G, Rubio L, Graham WAC, Bell DC, Bousfield D, Demokritou P. Development of high throughput, high precision synthesis platforms and characterization methodologies for toxicological studies of nanocellulose. Cellulose (Lond). 2018 Mar 03; 25:2303-2319. PMID: 31839698.
    Citations: 6     
  40. Thomas DG, Smith JN, Thrall BD, Baer DR, Jolley H, Munusamy P, Kodali V, Demokritou P, Cohen J, Teeguarden JG. ISD3: a particokinetic model for predicting the combined effects of particle sedimentation, diffusion and dissolution on cellular dosimetry for in vitro systems. Part Fibre Toxicol. 2018 01 25; 15(1):6. PMID: 29368623.
    Citations: 14     Fields:    Translation:AnimalsCells
  41. Cohen JM, Beltran-Huarac J, Pyrgiotakis G, Demokritou P. Effective delivery of sonication energy to fast settling and agglomerating nanomaterial suspensions for cellular studies: Implications for stability, particle kinetics, dosimetry and toxicity. NanoImpact. 2018 Apr; 10:81-86. PMID: 29479575.
    Citations: 16     
  42. Beltran-Huarac J, Zhang Z, Pyrgiotakis G, DeLoid G, Vaze N, Hussain SM, Demokritou P. Development of reference metal and metal oxide engineered nanomaterials for nanotoxicology research using high throughput and precision flame spray synthesis approaches. NanoImpact. 2018 Apr; 10:26-37. PMID: 30035243.
    Citations: 16     
  43. Li Q, Li T, Liu C, DeLoid G, Pyrgiotakis G, Demokritou P, Zhang R, Xiao H, McClements DJ. Potential impact of inorganic nanoparticles on macronutrient digestion: titanium dioxide nanoparticles slightly reduce lipid digestion under simulated gastrointestinal conditions. Nanotoxicology. 2017 Nov - Dec; 11(9-10):1087-1101. PMID: 29160733.
    Citations: 1     Fields:    Translation:Cells
  44. Konduru NV, Molina RM, Swami A, Damiani F, Pyrgiotakis G, Lin P, Andreozzi P, Donaghey TC, Demokritou P, Krol S, Kreyling W, Brain JD. Protein corona: implications for nanoparticle interactions with pulmonary cells. Part Fibre Toxicol. 2017 10 30; 14(1):42. PMID: 29084556.
    Citations: 12     Fields:    Translation:AnimalsCells
  45. Zhao J, Zhang Y, Sisler JD, Shaffer J, Leonard SS, Morris AM, Qian Y, Bello D, Demokritou P. Assessment of reactive oxygen species generated by electronic cigarettes using acellular and cellular approaches. J Hazard Mater. 2018 Feb 15; 344:549-557. PMID: 29102637.
    Citations: 8     Fields:    Translation:HumansCells
  46. DeLoid GM, Wang Y, Kapronezai K, Lorente LR, Zhang R, Pyrgiotakis G, Konduru NV, Ericsson M, White JC, De La Torre-Roche R, Xiao H, McClements DJ, Demokritou P. An integrated methodology for assessing the impact of food matrix and gastrointestinal effects on the biokinetics and cellular toxicity of ingested engineered nanomaterials. Part Fibre Toxicol. 2017 10 13; 14(1):40. PMID: 29029643.
    Citations: 22     Fields:    Translation:HumansCells
  47. Vaze N, Jiang Y, Mena L, Zhang Y, Bello D, Leonard SS, Morris AM, Eleftheriadou M, Pyrgiotakis G, Demokritou P. An integrated electrolysis - electrospray - ionization antimicrobial platform using Engineered Water Nanostructures (EWNS) for food safety applications. Food Control. 2018 Mar; 85:151-160. PMID: 29332999.
    Citations: 6     
  48. Chalbot MG, Pirela SV, Schifman L, Kasaraneni V, Oyanedel-Craver V, Bello D, Castranova V, Qian Y, Thomas T, Kavouras IG, Demokritou P. Synergistic effects of engineered nanoparticles and organics released from laser printers using nano-enabled toners: potential health implications from exposures to the emitted organic aerosol. Environ Sci Nano. 2017 Nov 01; 4(11):2144-2156. PMID: 30197786.
    Citations: 1     
  49. Pirela SV, Martin J, Bello D, Demokritou P. Nanoparticle exposures from nano-enabled toner-based printing equipment and human health: state of science and future research needs. Crit Rev Toxicol. 2017 Sep; 47(8):678-704. PMID: 28524743.
    Citations: 9     Fields:    Translation:HumansAnimalsPHPublic Health
  50. McClements DJ, Xiao H, Demokritou P. Physicochemical and colloidal aspects of food matrix effects on gastrointestinal fate of ingested inorganic nanoparticles. Adv Colloid Interface Sci. 2017 Aug; 246:165-180. PMID: 28552424.
    Citations: 12     Fields:    
  51. Singh D, Schifman LA, Watson-Wright C, Sotiriou GA, Oyanedel-Craver V, Wohlleben W, Demokritou P. Nanofiller Presence Enhances Polycyclic Aromatic Hydrocarbon (PAH) Profile on Nanoparticles Released during Thermal Decomposition of Nano-enabled Thermoplastics: Potential Environmental Health Implications. Environ Sci Technol. 2017 May 02; 51(9):5222-5232. PMID: 28397486.
    Citations: 4     Fields:    Translation:PHPublic Health
  52. Jiang Y, Sokorai K, Pyrgiotakis G, Demokritou P, Li X, Mukhopadhyay S, Jin T, Fan X. Cold plasma-activated hydrogen peroxide aerosol inactivates Escherichia coli O157:H7, Salmonella Typhimurium, and Listeria innocua and maintains quality of grape tomato, spinach and cantaloupe. Int J Food Microbiol. 2017 May 16; 249:53-60. PMID: 28319798.
    Citations: 3     Fields:    Translation:HumansAnimalsCellsPHPublic Health
  53. DeLoid GM, Cohen JM, Pyrgiotakis G, Demokritou P. Preparation, characterization, and in vitro dosimetry of dispersed, engineered nanomaterials. Nat Protoc. 2017 02; 12(2):355-371. PMID: 28102836.
    Citations: 46     Fields:    Translation:HumansAnimalsCells
  54. Martin J, Demokritou P, Woskie S, Bello D. Indoor Air Quality in Photocopy Centers, Nanoparticle Exposures at Photocopy Workstations, and the Need for Exposure Controls. Ann Work Expo Health. 2017 01 01; 61(1):110-122. PMID: 28395317.
    Citations: 4     Fields:    Translation:HumansPHPublic Health
  55. Watson-Wright C, Singh D, Demokritou P. Toxicological Implications of Released Particulate Matter during Thermal Decomposition of Nano-Enabled Thermoplastics. NanoImpact. 2017 Jan; 5:29-40. PMID: 29333505.
    Citations: 6     
  56. Eleftheriadou M, Pyrgiotakis G, Demokritou P. Nanotechnology to the rescue: using nano-enabled approaches in microbiological food safety and quality. Curr Opin Biotechnol. 2017 04; 44:87-93. PMID: 27992831.
    Citations: 16     Fields:    Translation:HumansPHPublic Health
  57. Stueckle TA, Davidson DC, Derk R, Kornberg TG, Schwegler-Berry D, Pirela SV, Deloid G, Demokritou P, Luanpitpong S, Rojanasakul Y, Wang L. Evaluation of tumorigenic potential of CeO2 and Fe2O3 engineered nanoparticles by a human cell in vitro screening model. NanoImpact. 2017 Apr; 6:39-54. PMID: 28367517.
    Citations: 6     
  58. Zhao J, Pyrgiotakis G, Demokritou P. Development and characterization of electronic-cigarette exposure generation system (Ecig-EGS) for the physico-chemical and toxicological assessment of electronic cigarette emissions. Inhal Toxicol. 2016 12; 28(14):658-669. PMID: 27829296.
    Citations: 8     Fields:    Translation:HumansPHPublic Health
  59. McClements DJ, DeLoid G, Pyrgiotakis G, Shatkin JA, Xiao H, Demokritou P. The Role of the Food Matrix and Gastrointestinal Tract in the assessment of biological properties of ingested engineered nanomaterials (iENMs): State of the science and knowledge gaps. NanoImpact. 2016 Jul; 3-4:47-57. PMID: 29568810.
    Citations: 20     
  60. DeLoid G, Casella B, Pirela S, Filoramo R, Pyrgiotakis G, Demokritou P, Kobzik L. Effects of engineered nanomaterial exposure on macrophage innate immune function. NanoImpact. 2016 Apr; 2:70-81. PMID: 29568809.
    Citations: 8     
  61. Konduru NV, Jimenez RJ, Swami A, Friend S, Castranova V, Demokritou P, Brain JD, Molina RM. Erratum to: Silica coating influences the corona and biokinetics of cerium oxide nanoparticles. Part Fibre Toxicol. 2016 06 22; 13(1):35. PMID: 27334863.
    Citations: 1     Fields:    
  62. Davidson DC, Derk R, He X, Stueckle TA, Cohen J, Pirela SV, Demokritou P, Rojanasakul Y, Wang L. Direct stimulation of human fibroblasts by nCeO2 in vitro is attenuated with an amorphous silica coating. Part Fibre Toxicol. 2016 05 04; 13(1):23. PMID: 27142434.
    Citations: 5     Fields:    Translation:HumansCells
  63. Watson CY, DeLoid GM, Pal A, Demokritou P. Buoyant Nanoparticles: Implications for Nano-Biointeractions in Cellular Studies. Small. 2016 Jun; 12(23):3172-3180. PMID: 27135209.
    Citations: 7     Fields:    
  64. Pyrgiotakis G, Vedantam P, Cirenza C, McDevitt J, Eleftheriadou M, Leonard SS, Demokritou P. Optimization of a nanotechnology based antimicrobial platform for food safety applications using Engineered Water Nanostructures (EWNS). Sci Rep. 2016 Feb 15; 6:21073. PMID: 26875817.
    Citations: 16     Fields:    Translation:AnimalsCellsPHPublic Health
  65. Pirela SV, Lu X, Miousse I, Sisler JD, Qian Y, Guo N, Koturbash I, Castranova V, Thomas T, Godleski J, Demokritou P. Effects of intratracheally instilled laser printer-emitted engineered nanoparticles in a mouse model: A case study of toxicological implications from nanomaterials released during consumer use. NanoImpact. 2016 Jan; 1:1-8. PMID: 26989787.
    Citations: 21     
  66. Sisler JD, Pirela SV, Shaffer J, Mihalchik AL, Chisholm WP, Andrew ME, Schwegler-Berry D, Castranova V, Demokritou P, Qian Y. Toxicological Assessment of CoO and La2O3 Metal Oxide Nanoparticles in Human Small Airway Epithelial Cells. Toxicol Sci. 2016 Apr; 150(2):418-28. PMID: 26769336.
    Citations: 5     Fields:    Translation:HumansCells
  67. Konduru NV, Murdaugh KM, Swami A, Jimenez RJ, Donaghey TC, Demokritou P, Brain JD, Molina RM. Surface modification of zinc oxide nanoparticles with amorphous silica alters their fate in the circulation. Nanotoxicology. 2016 08; 10(6):720-7. PMID: 26581431.
    Citations: 11     Fields:    Translation:Animals
  68. Sotiriou GA, Singh D, Zhang F, Chalbot MG, Spielman-Sun E, Hoering L, Kavouras IG, Lowry GV, Wohlleben W, Demokritou P. Thermal decomposition of nano-enabled thermoplastics: Possible environmental health and safety implications. J Hazard Mater. 2016 Mar 15; 305:87-95. PMID: 26642449.
    Citations: 12     Fields:    Translation:PHPublic Health
  69. Lu X, Miousse IR, Pirela SV, Moore JK, Melnyk S, Koturbash I, Demokritou P. In vivo epigenetic effects induced by engineered nanomaterials: A case study of copper oxide and laser printer-emitted engineered nanoparticles. Nanotoxicology. 2016; 10(5):629-39. PMID: 26559097.
    Citations: 21     Fields:    Translation:HumansAnimalsCells
  70. DeLoid GM, Cohen JM, Pyrgiotakis G, Pirela SV, Pal A, Liu J, Srebric J, Demokritou P. Advanced computational modeling for in vitro nanomaterial dosimetry. Part Fibre Toxicol. 2015 Oct 24; 12:32. PMID: 26497802.
    Citations: 40     Fields:    
  71. Konduru NV, Jimenez RJ, Swami A, Friend S, Castranova V, Demokritou P, Brain JD, Molina RM. Silica coating influences the corona and biokinetics of cerium oxide nanoparticles. Part Fibre Toxicol. 2015 Oct 12; 12:31. PMID: 26458946.
    Citations: 15     Fields:    Translation:Animals
  72. Cohen JM, DeLoid GM, Demokritou P. A critical review of in vitro dosimetry for engineered nanomaterials. Nanomedicine (Lond). 2015 Oct; 10(19):3015-3032. PMID: 26419834.
    Citations: 24     Fields:    
  73. Miousse IR, Chalbot MC, Pathak R, Lu X, Nzabarushimana E, Krager K, Aykin-Burns N, Hauer-Jensen M, Demokritou P, Kavouras IG, Koturbash I. In Vitro Toxicity and Epigenotoxicity of Different Types of Ambient Particulate Matter. Toxicol Sci. 2015 Dec; 148(2):473-87. PMID: 26342214.
    Citations: 8     Fields:    Translation:AnimalsCells
  74. Pal AK, Bello D, Cohen J, Demokritou P. Implications of in vitro dosimetry on toxicological ranking of low aspect ratio engineered nanomaterials. Nanotoxicology. 2015; 9(7):871-85. PMID: 25672815.
    Citations: 26     Fields:    Translation:HumansCells
  75. Ma J, Mercer RR, Barger M, Schwegler-Berry D, Cohen JM, Demokritou P, Castranova V. Effects of amorphous silica coating on cerium oxide nanoparticles induced pulmonary responses. Toxicol Appl Pharmacol. 2015 Oct 01; 288(1):63-73. PMID: 26210349.
    Citations: 15     Fields:    Translation:Animals
  76. Martin J, Bello D, Bunker K, Shafer M, Christiani D, Woskie S, Demokritou P. Occupational exposure to nanoparticles at commercial photocopy centers. J Hazard Mater. 2015 Nov 15; 298:351-60. PMID: 26148960.
    Citations: 7     Fields:    Translation:HumansPHPublic Health
  77. Pirela SV, Miousse IR, Lu X, Castranova V, Thomas T, Qian Y, Bello D, Kobzik L, Koturbash I, Demokritou P. Effects of Laser Printer-Emitted Engineered Nanoparticles on Cytotoxicity, Chemokine Expression, Reactive Oxygen Species, DNA Methylation, and DNA Damage: A Comprehensive in Vitro Analysis in Human Small Airway Epithelial Cells, Macrophages, and Lymphoblasts. Environ Health Perspect. 2016 Feb; 124(2):210-9. PMID: 26080392.
    Citations: 15     Fields:    Translation:HumansCells
  78. Sotiriou GA, Singh D, Zhang F, Wohlleben W, Chalbot MG, Kavouras IG, Demokritou P. An integrated methodology for the assessment of environmental health implications during thermal decomposition of nano-enabled products. Environ Sci Nano. 2015 Jun 01; 2(3):262-272. PMID: 26200119.
    Citations: 9     
  79. Pal AK, Watson CY, Pirela SV, Singh D, Chalbot MC, Kavouras I, Demokritou P. Linking Exposures of Particles Released From Nano-Enabled Products to Toxicology: An Integrated Methodology for Particle Sampling, Extraction, Dispersion, and Dosing. Toxicol Sci. 2015 Aug; 146(2):321-33. PMID: 25997654.
    Citations: 15     Fields:    Translation:HumansPHPublic Health
  80. Lu X, Miousse IR, Pirela SV, Melnyk S, Koturbash I, Demokritou P. Short-term exposure to engineered nanomaterials affects cellular epigenome. Nanotoxicology. 2016; 10(2):140-50. PMID: 25938281.
    Citations: 23     Fields:    Translation:HumansAnimalsCellsPHPublic Health
  81. Pyrgiotakis G, Vasanthakumar A, Gao Y, Eleftheriadou M, Toledo E, DeAraujo A, McDevitt J, Han T, Mainelis G, Mitchell R, Demokritou P. Inactivation of foodborne microorganisms using engineered water nanostructures (EWNS). Environ Sci Technol. 2015 Mar 17; 49(6):3737-45. PMID: 25695127.
    Citations: 14     Fields:    Translation:AnimalsCellsPHPublic Health
  82. Zhou EH, Watson C, Pizzo R, Cohen J, Dang Q, Ferreira de Barros PM, Park CY, Chen C, Brain JD, Butler JP, Ruberti JW, Fredberg JJ, Demokritou P. Assessing the impact of engineered nanoparticles on wound healing using a novel in vitro bioassay. Nanomedicine (Lond). 2014 Dec; 9(18):2803-15. PMID: 24823434.
    Citations: 12     Fields:    Translation:HumansAnimalsCells
  83. Sisler JD, Pirela SV, Friend S, Farcas M, Schwegler-Berry D, Shvedova A, Castranova V, Demokritou P, Qian Y. Small airway epithelial cells exposure to printer-emitted engineered nanoparticles induces cellular effects on human microvascular endothelial cells in an alveolar-capillary co-culture model. Nanotoxicology. 2015; 9(6):769-79. PMID: 25387250.
    Citations: 19     Fields:    Translation:HumansCells
  84. Pirela SV, Sotiriou GA, Bello D, Shafer M, Bunker KL, Castranova V, Thomas T, Demokritou P. Consumer exposures to laser printer-emitted engineered nanoparticles: A case study of life-cycle implications from nano-enabled products. Nanotoxicology. 2015; 9(6):760-8. PMID: 25387251.
    Citations: 18     Fields:    Translation:HumansPHPublic Health
  85. Yokel RA, Hussain S, Garantziotis S, Demokritou P, Castranova V, Cassee FR. The Yin: An adverse health perspective of nanoceria: uptake, distribution, accumulation, and mechanisms of its toxicity. Environ Sci Nano. 2014 Oct 01; 1(5):406-428. PMID: 25243070.
    Citations: 22     
  86. Konduru NV, Murdaugh KM, Sotiriou GA, Donaghey TC, Demokritou P, Brain JD, Molina RM. Bioavailability, distribution and clearance of tracheally-instilled and gavaged uncoated or silica-coated zinc oxide nanoparticles. Part Fibre Toxicol. 2014 Sep 03; 11:44. PMID: 25183210.
    Citations: 19     Fields:    Translation:AnimalsPHPublic Health
  87. Pal AK, Aalaei I, Gadde S, Gaines P, Schmidt D, Demokritou P, Bello D. High resolution characterization of engineered nanomaterial dispersions in complex media using tunable resistive pulse sensing technology. ACS Nano. 2014 Sep 23; 8(9):9003-15. PMID: 25093451.
    Citations: 12     Fields:    Translation:HumansCells
  88. Okello VA, Gass S, Pyrgiotakis G, Du N, Lake A, Kariuki V, Sotiriou GA, Addolorato J, Demokritou P, Sadik OA. Capture, isolation and electrochemical detection of industrially-relevant engineered aerosol nanoparticles using poly (amic) acid, phase-inverted, nano-membranes. J Hazard Mater. 2014 Aug 30; 279:365-74. PMID: 25080157.
    Citations:    Fields:    Translation:Cells
  89. Pyrgiotakis G, Blattmann CO, Demokritou P. Real-Time Nanoparticle-Cell Interactions in Physiological Media by Atomic Force Microscopy. ACS Sustain Chem Eng. 2014 Jul 07; 2(7):1681-1690. PMID: 25068097.
    Citations: 13     
  90. Pirela SV, Pyrgiotakis G, Bello D, Thomas T, Castranova V, Demokritou P. Development and characterization of an exposure platform suitable for physico-chemical, morphological and toxicological characterization of printer-emitted particles (PEPs). Inhal Toxicol. 2014 Jun; 26(7):400-8. PMID: 24862974.
    Citations: 16     Fields:    Translation:HumansAnimalsPHPublic Health
  91. Cohen JM, Teeguarden JG, Demokritou P. An integrated approach for the in vitro dosimetry of engineered nanomaterials. Part Fibre Toxicol. 2014 May 01; 11:20. PMID: 24885440.
    Citations: 59     Fields:    Translation:HumansAnimals
  92. Sotiriou GA, Watson C, Murdaugh KM, Darrah TH, Pyrgiotakis G, Elder A, Brain JD, Demokritou P. Engineering safer-by-design, transparent, silica-coated ZnO nanorods with reduced DNA damage potential. Environ Sci Nano. 2014 Apr; 1(2):144-153. PMID: 24955241.
    Citations: 28     
  93. DeLoid G, Cohen JM, Darrah T, Derk R, Rojanasakul L, Pyrgiotakis G, Wohlleben W, Demokritou P. Estimating the effective density of engineered nanomaterials for in vitro dosimetry. Nat Commun. 2014 Mar 28; 5:3514. PMID: 24675174.
    Citations: 75     Fields:    Translation:HumansCells
  94. Pyrgiotakis G, McDevitt J, Gao Y, Branco A, Eleftheriadou M, Lemos B, Nardell E, Demokritou P. Mycobacteria inactivation using Engineered Water Nanostructures (EWNS). Nanomedicine. 2014 Aug; 10(6):1175-83. PMID: 24632246.
    Citations: 11     Fields:    Translation:CellsPHPublic Health
  95. Watson C, Ge J, Cohen J, Pyrgiotakis G, Engelward BP, Demokritou P. High-throughput screening platform for engineered nanoparticle-mediated genotoxicity using CometChip technology. ACS Nano. 2014 Mar 25; 8(3):2118-33. PMID: 24617523.
    Citations: 37     Fields:    Translation:HumansAnimalsCells
  96. Cohen JM, Derk R, Wang L, Godleski J, Kobzik L, Brain J, Demokritou P. Tracking translocation of industrially relevant engineered nanomaterials (ENMs) across alveolar epithelial monolayers in vitro. Nanotoxicology. 2014 Aug; 8 Suppl 1:216-25. PMID: 24479615.
    Citations: 30     Fields:    Translation:HumansCells
  97. Pyrgiotakis G, McDevitt J, Bordini A, Diaz E, Molina R, Watson C, Deloid G, Lenard S, Fix N, Mizuyama Y, Yamauchi T, Brain J, Demokritou P. A chemical free, nanotechnology-based method for airborne bacterial inactivation using engineered water nanostructures. Environ Sci Nano. 2014; 2014(1):15-26. PMID: 26180637.
    Citations: 14     
  98. Khatri M, Bello D, Pal AK, Woskie S, Gassert TH, Demokritou P, Gaines P. Toxicological effects of PM0.25-2.0 particles collected from a photocopy center in three human cell lines. Inhal Toxicol. 2013 Sep; 25(11):621-32. PMID: 24044678.
    Citations: 6     Fields:    Translation:HumansCells
  99. Pyrgiotakis G, Blattmann CO, Pratsinis S, Demokritou P. Nanoparticle-nanoparticle interactions in biological media by atomic force microscopy. Langmuir. 2013 Sep 10; 29(36):11385-95. PMID: 23978039.
    Citations: 18     Fields:    Translation:Animals
  100. Khatri M, Bello D, Pal AK, Cohen JM, Woskie S, Gassert T, Lan J, Gu AZ, Demokritou P, Gaines P. Evaluation of cytotoxic, genotoxic and inflammatory responses of nanoparticles from photocopiers in three human cell lines. Part Fibre Toxicol. 2013 Aug 22; 10:42. PMID: 23968360.
    Citations: 24     Fields:    Translation:HumansCells
  101. Pirela S, Molina R, Watson C, Cohen JM, Bello D, Demokritou P, Brain J. Effects of copy center particles on the lungs: a toxicological characterization using a Balb/c mouse model. Inhal Toxicol. 2013 Aug; 25(9):498-508. PMID: 23895351.
    Citations: 24     Fields:    Translation:Animals
  102. Gass S, Cohen JM, Pyrgiotakis G, Sotiriou GA, Pratsinis SE, Demokritou P. A Safer Formulation Concept for Flame-Generated Engineered Nanomaterials. ACS Sustain Chem Eng. 2013 Jul 01; 1(7):843-857. PMID: 23961338.
    Citations: 29     
  103. Chang C, Demokritou P, Shafer M, Christiani D. Physicochemical and toxicological characteristics of welding fume derived particles generated from real time welding processes. Environ Sci Process Impacts. 2013 Jan; 15(1):214-24. PMID: 24592438.
    Citations: 18     Fields:    Translation:HumansPHPublic Health
  104. Demokritou P, Gass S, Pyrgiotakis G, Cohen JM, Goldsmith W, McKinney W, Frazer D, Ma J, Schwegler-Berry D, Brain J, Castranova V. An in vivo and in vitro toxicological characterisation of realistic nanoscale CeO2 inhalation exposures. Nanotoxicology. 2013 Dec; 7(8):1338-50. PMID: 23061914.
    Citations: 57     Fields:    Translation:HumansAnimalsCellsPHPublic Health
  105. Bello D, Martin J, Santeufemio C, Sun Q, Lee Bunker K, Shafer M, Demokritou P. Physicochemical and morphological characterisation of nanoparticles from photocopiers: implications for environmental health. Nanotoxicology. 2013 Aug; 7(5):989-1003. PMID: 22551088.
    Citations: 26     Fields:    Translation:PHPublic Health
  106. Tsai CS, Echevarría-Vega ME, Sotiriou GA, Santeufemio C, Schmidt D, Demokritou P, Ellenbecker M. Evaluation of environmental filtration control of engineered nanoparticles using the Harvard Versatile Engineered Nanomaterial Generation System (VENGES). J Nanopart Res. 2012 May; 14(5). PMID: 23412707.
    Citations: 2     
  107. Cohen J, Deloid G, Pyrgiotakis G, Demokritou P. Interactions of engineered nanomaterials in physiological media and implications for in vitro dosimetry. Nanotoxicology. 2013 Jun; 7(4):417-31. PMID: 22393878.
    Citations: 74     Fields:    Translation:HumansCells
  108. Sotiriou GA, Diaz E, Long MS, Godleski J, Brain J, Pratsinis SE, Demokritou P. A novel platform for pulmonary and cardiovascular toxicological characterization of inhaled engineered nanomaterials. Nanotoxicology. 2012 Sep; 6(6):680-90. PMID: 21809902.
    Citations: 28     Fields:    Translation:AnimalsPHPublic Health
  109. Zhu S, Srebric J, Spengler JD, Demokritou P. An advanced numerical model for the assessment of airborne transmission of influenza in bus microenvironments. Build Environ. 2012 Jan; 47:67-75. PMID: 32288019.
    Citations: 2     
  110. Demokritou P, Büchel R, Molina RM, Deloid GM, Brain JD, Pratsinis SE. Development and characterization of a Versatile Engineered Nanomaterial Generation System (VENGES) suitable for toxicological studies. Inhal Toxicol. 2010 Dec; 22 Suppl 2:107-16. PMID: 20701428.
    Citations: 34     Fields:    Translation:HumansAnimalsCells
  111. Middleton N, Yiallouros P, Nicolaou N, Kleanthous S, Pipis S, Zeniou M, Demokritou P, Koutrakis P. Residential exposure to motor vehicle emissions and the risk of wheezing among 7-8 year-old schoolchildren: a city-wide cross-sectional study in Nicosia, Cyprus. Environ Health. 2010 Jun 18; 9:28. PMID: 20565827.
    Citations: 3     Fields:    Translation:HumansPHPublic Health
  112. Zhu S, Demokritou P, Spengler J. Experimental and numerical investigation of micro-environmental conditions in public transportation buses. Build Environ. 2010 Oct; 45(10):2077-2088. PMID: 32288006.
    Citations: 2     
  113. Christophi CA, Savvides EC, Warren CW, Demokritou P, Connolly GN. Main determinants of cigarette smoking in youth based on the 2006 Cyprus GYTS. Prev Med. 2009 Mar; 48(3):232-6. PMID: 19272301.
    Citations: 8     Fields:    Translation:Humans
  114. Middleton N, Yiallouros P, Kleanthous S, Kolokotroni O, Schwartz J, Dockery DW, Demokritou P, Koutrakis P. A 10-year time-series analysis of respiratory and cardiovascular morbidity in Nicosia, Cyprus: the effect of short-term changes in air pollution and dust storms. Environ Health. 2008 Jul 22; 7:39. PMID: 18647382.
    Citations: 48     Fields:    Translation:Humans
  115. Christophi CA, Kolokotroni O, Alpert HR, Warren CW, Jones NR, Demokritou P, Connolly GN. Prevalence and social environment of cigarette smoking in Cyprus youth. BMC Public Health. 2008 Jun 02; 8:190. PMID: 18518947.
    Citations: 11     Fields:    Translation:Humans
  116. Sotiriou M, Ferguson SF, Davey M, Wolfson JM, Demokritou P, Lawrence J, Sax SN, Koutrakis P. Measurement of particle concentrations in a dental office. Environ Monit Assess. 2008 Feb; 137(1-3):351-61. PMID: 17505900.
    Citations: 4     Fields:    Translation:PHPublic Health
  117. Koutrakis P, Sax SN, Sarnat JA, Coull B, Demokritou P, Oyola P, Garcia J, Gramsch E. Analysis of PM10, PM2.5, and PM2 5-10 concentrations in Santiago, Chile, from 1989 to 2001. J Air Waste Manag Assoc. 2005 Mar; 55(3):342-51. PMID: 15828676.
    Citations: 9     Fields:    Translation:PHPublic Health
  118. Gupta T, Demokritou P, Koutrakis P. Development and performance evaluation of a high-volume ultrafine particle concentrator for inhalation toxicological studies. Inhal Toxicol. 2004 Dec 01; 16(13):851-62. PMID: 15513817.
    Citations: 9     Fields:    Translation:PHPublic Health
  119. Demokritou P, Gupta T, Ferguson S, Koutrakis P. Development of a high-volume concentrated ambient particles system (CAPS) for human and animal inhalation toxicological studies. Inhal Toxicol. 2003 Feb; 15(2):111-29. PMID: 12528042.
    Citations: 7     Fields:    Translation:HumansAnimals
  120. Sarnat JA, Demokritou P, Koutrakis P. Measurement of fine, coarse and ultrafine particles. Ann Ist Super Sanita. 2003; 39(3):351-5. PMID: 15098555.
    Citations: 1     Fields:    Translation:PHPublic Health
  121. Demokritou P, Gupta T, Ferguson S, Koutrakis P. Development and laboratory performance evaluation of a personal cascade impactor. J Air Waste Manag Assoc. 2002 Oct; 52(10):1230-7. PMID: 12418733.
    Citations: 5     Fields:    Translation:CellsPHPublic Health
  122. Yang C, Demokritou P, Chen Q, Spengler J. Experimental validation of a computational fluid dynamics model for IAQ applications in ice rink arenas. Indoor Air. 2001 Jun; 11(2):120-6. PMID: 11394010.
    Citations: 1     Fields:    Translation:HumansPHPublic Health
  123. Demokritou P, Kavouras IG, Harrison D, Koutrakis P. Development and evaluation of an impactor for a PM2.5 speciation sampler. J Air Waste Manag Assoc. 2001 Apr; 51(4):514-23. PMID: 11321908.
    Citations: 6     Fields:    Translation:PHPublic Health
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.