David Allan Williams, M.D.
Title Leland Fikes Professor of Pediatrics Institution Boston Children's Hospital Address Childrens Hospital Karp Family Research Bldg, 8th floor 300 Longwood Ave Boston MA 02115
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Research
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OT2HL154815
(WILLIAMS, DAVID A)
Jul 22, 2020 - Aug 31, 2021
Gene therapy targeting BCL11A to induce fetal hemoglobin and reduce sickle hemoglobin in patients with Sickle Cell Disease
Role: Principal Investigator
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OT2HL152639
(WILLIAMS, DAVID A)
Sep 20, 2019 - Apr 17, 2020
Boston Consortium to Cure SCD - Williams/John Higgins
Role: Principal Investigator
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OT2HL152640
(WILLIAMS, DAVID A)
Sep 20, 2019 - Feb 17, 2020
Boston Consortium to Cure SCD - Williams/Ellen Grant
Role: Principal Investigator
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R01HL137848
(WILLIAMS, DAVID A)
Sep 5, 2017 - Jun 30, 2022
Gene therapy targeting BCL11A to induce fetal hemoglobin and reduce sickle hemoglobin in patients with Sickle Cell Disease
Role: Principal Investigator
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R56AI125766
(SNAPPER, SCOTT B)
Aug 8, 2017 - Jul 31, 2019
Employing novel humanized murine strains to develop hematopoietic stem cell gene therapeutic approaches for very early-onset inflammatory bowel disease due to IL10-receptor deficiency.
Role: Co-Principal Investigator
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R34HL133384
(WILLIAMS, DAVID A)
Apr 10, 2017 - Mar 31, 2021
Feasibility study randomizing IST vs URD BMT for children with aplastic anemia
Role: Principal Investigator
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U01TR001814
(WILLIAMS, DAVID A)
Sep 16, 2016 - Jun 30, 2021
Disseminating Curative Biological Therapies for Rare Pediatric Diseases
Role: Co-Principal Investigator
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R01CA202756
(WILLIAMS, DAVID A)
Jul 20, 2016 - Jun 30, 2021
Development of novel selective Rac inhibitors for refractory leukemias
Role: Principal Investigator
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U01AI125051
(WILLIAMS, DAVID A)
Jul 7, 2016 - Jun 30, 2022
Gene therapy for SCID-X1 with low dose busulfan and a SIN-lentiviral vector
Role: Principal Investigator
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R24DK099808
(SHIMAMURA, AKIKO)
Sep 29, 2013 - Aug 31, 2019
Translational Studies of Inherited Marrow Failure and Myelodysplastic Syndromes
Role: Co-Principal Investigator
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U01HL117720
(SANKARAN, VIJAY GANESH)
Aug 15, 2013 - May 31, 2019
Translational and clinical studies targeting y-globin modulation
Role: Principal Investigator
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R24DK094746
(WILLIAMS, DAVID A)
Aug 1, 2012 - Feb 28, 2014
Molecular Genetic Investigation of Pediatric Myelodysplastic Syndrome
Role: Co-Principal Investigator
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RC4DK090913
(WILLIAMS, DAVID A)
Sep 23, 2010 - Aug 31, 2013
Novel therapies for Fanconi anemia
Role: Co-Principal Investigator
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U01AI087628
(WILLIAMS, DAVID A)
Sep 1, 2010 - Aug 31, 2017
Gene Therapy for SCID-X1 using a self-inactivating (SIN) gammaretroviral vector
Role: Principal Investigator
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RC1DK086861
(WILLIAMS, DAVID A)
Sep 21, 2009 - Jul 31, 2012
Development of a Pediatric Mylelodysplastic Syndrome Patient Registry
Role: Co-Principal Investigator
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U01DK082345
(CLAUW, DANIEL J)
Sep 15, 2008 - Jun 30, 2019
University of Michigan MAPP Research Network Discovery Site
Role: Co-Principal Investigator
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R01HL081499
(WILLIAMS, DAVID A)
Apr 1, 2006 - Mar 31, 2010
Novel Molecular and Cellular Therapies in Fanconi Anemia
Role: Principal Investigator
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R01DK074310
(WILLIAMS, DAVID A)
Jan 1, 2006 - Dec 31, 2010
Chemoresistance and Stem Cell Selection
Role: Principal Investigator
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R01CA113969
(WILLIAMS, DAVID A)
May 20, 2005 - Jun 30, 2015
RhoH GTPase in Hematopoiesis and Cancer
Role: Principal Investigator
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P01HL069974
(SKALNIK, DAVID G)
Apr 22, 2002 - Mar 31, 2008
Role of Rac2 in Development and Function of Blood Cells
Role: Co-Principal Investigator
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R01DK062757
(WILLIAMS, DAVID A)
Apr 1, 2002 - Dec 31, 2017
Rac proteins in hematopoietic cell survival and function
Role: Principal Investigator
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P30CA082709
(LOEHRER, PATRICK J.)
Sep 22, 1999 - Aug 31, 2019
Indiana University Melvin and Bren Simon Cancer Center Support Grant
Role: Co-Principal Investigator
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P30DK049218
(SROUR, EDWARD F)
Sep 15, 1999 - Aug 31, 2006
CORE CENTERS OF EXCELLENCE IN MOLECULAR HEMATOLOGY
Role: Co-Principal Investigator
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P01CA075426
(ERICKSON, LEONARD C)
May 11, 1998 - Feb 28, 2006
DOSE INTENSIFICATION BY GENE TRANSDUCTION IN CANCER
Role: Co-Principal Investigator
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P50DK049218
(WILLIAMS, DAVID A)
Sep 30, 1994 - Aug 31, 1999
GENETIC MODIFICATION/ALTERNATIVE SOURCES OF STEM CELL
Role: Co-Principal Investigator
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R01DK048605
(WILLIAMS, DAVID A)
Aug 1, 1994 - Jul 31, 2003
STEEL GENE PRODUCT AND STEM CELL PROLIFERATION
Role: Principal Investigator
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M01RR008084
(STRAUSS, ARNOLD W)
Dec 30, 1993 - Nov 30, 2011
General Clinical Research Center
Role: Co-Principal Investigator
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P20DK047468
(WILLIAMS, DAVID A)
Sep 30, 1993 - Oct 31, 1994
GENETIC MODIFICATIONS/ALTERNATIVE SOURCES OF STEM CELLS
Role: Principal Investigator
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R01HL046528
(WILLIAMS, DAVID A)
Nov 1, 1991 - May 31, 1996
ADHESION AND STEM CELL SURVIVAL AND ENGRAFTMENT
Role: Principal Investigator
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K08HL001554
(WILLIAMS, DAVID A)
Jul 1, 1985 - Jun 30, 1990
RETROVIRAL MEDIATED GENE TRANSFER INTO BONE MARROW CELLS
Role: Principal Investigator
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M01RR000042
(KELCH, ROBERT P)
Dec 1, 1977 - Feb 28, 2011
General Clinical Research Center
Role: Co-Principal Investigator
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T32HL007574
(WILLIAMS, DAVID A)
Jul 1, 1975 - Jun 30, 2025
Pathophysiology of Human Blood Cells
Role: Principal Investigator
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P01CA059348
Sep 29, 1996
RETROVIRAL VECTOR APPLICATION TO CHILDHOOD BRAIN TUMOR TREATMENT
Role: Co-Principal Investigator

Bibliographic
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