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Indranil Sinha, M.D.

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Research
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. R21EB026824 (SHIN, SU RYON) Sep 20, 2018 - Jun 30, 2021
    NIH
    Programmable multimaterial bioprinting of 3D vascularized tissue constructs
    Role: Co-Investigator
  2. R01AR073822 (TAMAYOL, ALI) Sep 1, 2018 - Aug 31, 2023
    NIH
    Microengineered scaffolds carrying patient-specific cells and growth factors for treatment of volumetric muscle loss
    Role: Co-Investigator
  3. K76AG059996 (SINHA, INDRANIL) Aug 1, 2018 - May 31, 2023
    NIH/NIA
    Aging-associated dysregulation of the hypoxia pathway limits skeletal muscle regeneration
    Role: Principal Investigator
  4. R01AR073135 (KHADEMHOSSEINI, ALI) May 1, 2018 - Mar 31, 2023
    NIH/NIAMS
    3D printed muscle-bone organ implant for treating large injuries
    Role: Co-Investigator
  5. F32AG034703 (SINHA, INDRANIL) Jul 1, 2009 - Jun 30, 2011
    NIH/NIA
    Reversing age-related dysfunction of skeletal muscle stem cells
    Role: Principal Investigator

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Roh DS, Panayi AC, Bhasin S, Orgill DP, Sinha I. Implications of Aging in Plastic Surgery. Plast Reconstr Surg Glob Open. 2019 Jan; 7(1):e2085. PMID: 30859042.
    Citations:    
  2. Rhodius P, Haddad A, Matsumine H, Sakthivel D, Ackermann M, Sinha I, Orgill DP, Giatsidis G. Noninvasive Flap Preconditioning by Foam-Mediated External Suction Improves the Survival of Fasciocutaneous Axial-Pattern Flaps in a Type 2 Diabetic Murine Model. Plast Reconstr Surg. 2018 12; 142(6):872e-883e. PMID: 30188471.
    Citations:    Fields:    
  3. Serebrakian AT, Pickrell BB, Varon DE, Mohamadi A, Grinstaff MW, Rodriguez EK, Nazarian A, Halvorson EG, Sinha I. Meta-analysis and Systematic Review of Skin Graft Donor-site Dressings with Future Guidelines. Plast Reconstr Surg Glob Open. 2018 Sep; 6(9):e1928. PMID: 30349793.
    Citations:    
  4. Krezdorn N, Sakthivel D, Turk M, Aycart MA, Tasigiorgos S, Bueno EM, Sinha I, Pomahac B. Reduced Hypoxia-Related Genes in Porcine Limbs in Ex Vivo Hypothermic Perfusion Versus Cold Storage. J Surg Res. 2018 12; 232:137-145. PMID: 30463709.
    Citations:    Fields:    
  5. Varon DE, Smith JD, Bharadia DR, Shafique N, Sakthivel D, Halvorson EG, Nuutila K, Sinha I. Use of a novel chitosan-based dressing on split-thickness skin graft donor sites: a pilot study. J Wound Care. 2018 Jul 01; 27(Sup7):S12-S18. PMID: 30008255.
    Citations:    Fields:    
  6. Faramarzi N, Yazdi IK, Nabavinia M, Gemma A, Fanelli A, Caizzone A, Ptaszek LM, Sinha I, Khademhosseini A, Ruskin JN, Tamayol A. Patient-Specific Bioinks for 3D Bioprinting of Tissue Engineering Scaffolds. Adv Healthc Mater. 2018 Jun; 7(11):e1701347. PMID: 29663706.
    Citations: 1     Fields:    
  7. Kruse CR, Sakthivel D, Sinha I, Helm D, Sørensen JA, Eriksson E, Nuutila K. Evaluation of the efficacy of cell and micrograft transplantation for full-thickness wound healing. J Surg Res. 2018 07; 227:35-43. PMID: 29804860.
    Citations:    Fields:    
  8. Sinha I, Giatsidis G, Orgill DP. Discussion: Protective Effect of Hydrogen Gas Inhalation on Muscular Damage Using a Mouse Hindlimb Ischemia-Reperfusion Injury Model. Plast Reconstr Surg. 2017 12; 140(6):1207-1208. PMID: 29176415.
    Citations:    Fields:    
  9. Sinha I, Chun YS. Reply: Late Surgical-Site Infection in Immediate Implant-Based Breast Reconstruction. Plast Reconstr Surg. 2017 11; 140(5):750e. PMID: 29068952.
    Citations:    Fields:    Translation:Humans
  10. Varon DE, Freitas G, Goel N, Wall J, Bharadia D, Sisk E, Vacanti JC, Pomahac B, Sinha I, Patel VM. Intraoperative Feeding Improves Calorie and Protein Delivery in Acute Burn Patients. J Burn Care Res. 2017 Sep/Oct; 38(5):299-303. PMID: 28296670.
    Citations:    Fields:    Translation:Humans
  11. Bharadia D, Sinha I, Pomahac B. Role of Facial Vascularized Composite Allotransplantation in Burn Patients. Clin Plast Surg. 2017 Oct; 44(4):857-864. PMID: 28888310.
    Citations:    Fields:    Translation:Humans
  12. Sinha I, Sakthivel D, Olenchock BA, Kruse CR, Williams J, Varon DE, Smith JD, Madenci AL, Nuutila K, Wagers AJ. Prolyl Hydroxylase Domain-2 Inhibition Improves Skeletal Muscle Regeneration in a Male Murine Model of Obesity. Front Endocrinol (Lausanne). 2017; 8:153. PMID: 28725215.
    Citations: 1     
  13. Nuutila K, Sakthivel D, Kruse C, Tran P, Giatsidis G, Sinha I. Gene expression profiling of skeletal muscle after volumetric muscle loss. Wound Repair Regen. 2017 05; 25(3):408-413. PMID: 28494512.
    Citations:    Fields:    Translation:Animals
  14. Kruse CR, Singh M, Targosinski S, Sinha I, Sørensen JA, Eriksson E, Nuutila K. The effect of pH on cell viability, cell migration, cell proliferation, wound closure, and wound reepithelialization: In vitro and in vivo study. Wound Repair Regen. 2017 04; 25(2):260-269. PMID: 28370923.
    Citations: 1     Fields:    Translation:AnimalsCells
  15. Giatsidis G, Sinha I, Pomahac B. Reflections on a Decade of Face Transplantation. Ann Surg. 2017 04; 265(4):841-846. PMID: 28032849.
    Citations: 2     Fields:    Translation:Humans
  16. Sinha I, Sakthivel D, Varon DE. Systemic Regulators of Skeletal Muscle Regeneration in Obesity. Front Endocrinol (Lausanne). 2017; 8:29. PMID: 28261159.
    Citations: 6     
  17. Sinha I, Pusic AL, Wilkins EG, Hamill JB, Chen X, Kim HM, Guldbrandsen G, Chun YS. Late Surgical-Site Infection in Immediate Implant-Based Breast Reconstruction. Plast Reconstr Surg. 2017 Jan; 139(1):20-28. PMID: 28027221.
    Citations: 4     Fields:    Translation:Humans
  18. Oh J, Sinha I, Tan KY, Rosner B, Dreyfuss JM, Gjata O, Tran P, Shoelson SE, Wagers AJ. Age-associated NF-?B signaling in myofibers alters the satellite cell niche and re-strains muscle stem cell function. Aging (Albany NY). 2016 11 14; 8(11):2871-2896. PMID: 27852976.
    Citations: 7     Fields:    Translation:HumansAnimalsCells
  19. Cossette SM, Bhute VJ, Bao X, Harmann LM, Horswill MA, Sinha I, Gastonguay A, Pooya S, Bordas M, Kumar SN, Mirza SP, Palecek SP, Strande JL, Ramchandran R. Sucrose Nonfermenting-Related Kinase Enzyme-Mediated Rho-Associated Kinase Signaling is Responsible for Cardiac Function. Circ Cardiovasc Genet. 2016 Dec; 9(6):474-486. PMID: 27780848.
    Citations: 2     Fields:    Translation:AnimalsCells
  20. Pollock M, Sinha IP, Hartling L, Rowe BH, Schreiber S, Fernandes RM. Inhaled short-acting bronchodilators for managing emergency childhood asthma: an overview of reviews. Allergy. 2017 Feb; 72(2):183-200. PMID: 27588581.
    Citations: 1     Fields:    Translation:Humans
  21. Singh M, Nuutila K, Sinha I, Eriksson E. Endotoxin-induced inflammation in a rodent model up-regulates IL-1a expression and CD45+ leukocyte recruitment and increases the rate of reepithelialization and wound closure. Wound Repair Regen. 2016 Sep; 24(5):820-828. PMID: 27387834.
    Citations: 2     Fields:    
  22. Martínez-Redondo V, Jannig PR, Correia JC, Ferreira DM, Cervenka I, Lindvall JM, Sinha I, Izadi M, Pettersson-Klein AT, Agudelo LZ, Gimenez-Cassina A, Brum PC, Dahlman-Wright K, Ruas JL. Peroxisome Proliferator-activated Receptor ? Coactivator-1 a Isoforms Selectively Regulate Multiple Splicing Events on Target Genes. J Biol Chem. 2016 07 15; 291(29):15169-84. PMID: 27231350.
    Citations: 8     Fields:    Translation:AnimalsCells
  23. Fukudome EY, Bharadia DR, Helm DL, Sinha I. Extended V-Y Advancement Flap Reconstruction of a Large Posterior Upper Midline Trunk Defect. Plast Reconstr Surg Glob Open. 2016 May; 4(5):e713. PMID: 27579237.
    Citations:    
  24. Lau FH, Sinha I, Jiang W, Lipsitz SR, Eriksson E. A Time Study of Plastic Surgery Residents. Ann Plast Surg. 2016 May; 76(5):541-4. PMID: 26954746.
    Citations:    Fields:    Translation:Humans
  25. Sinha I, Orgill DP. Discussion: Opposite Effects of Soluble Factors Secreted by Adipose Tissue on Proliferating and Quiescent Osteosarcoma Cells. Plast Reconstr Surg. 2016 Mar; 137(3):876-7. PMID: 26910667.
    Citations:    Fields:    Translation:HumansAnimals
  26. Wang Y, Fisahn A, Sinha I, Nguyen DP, Sterzenbach U, Lallemend F, Hadjab S. Hippocampal Transcriptome Profile of Persistent Memory Rescue in a Mouse Model of THRA1 Mutation-Mediated Resistance to Thyroid Hormone. Sci Rep. 2016 Jan 08; 6:18617. PMID: 26743578.
    Citations: 1     Fields:    Translation:HumansAnimalsCells
  27. Sinha I, Zhu D, Ojomo K, Gfrerer L, Sawh-Martinez R, Patel A, Chan RK, Watkins JF. Functional and subjective assessment of burn contracture release in a mission setting. Burns. 2016 Mar; 42(2):466-70. PMID: 26778704.
    Citations:    Fields:    Translation:Humans
  28. Berglind D, Müller P, Willmer M, Sinha I, Tynelius P, Näslund E, Dahlman-Wright K, Rasmussen F. Differential methylation in inflammation and type 2 diabetes genes in siblings born before and after maternal bariatric surgery. Obesity (Silver Spring). 2016 Jan; 24(1):250-61. PMID: 26637991.
    Citations:    
  29. Baylan JM, Chambers JA, McMullin N, Fletcher JL, Sinha I, Lundy J, King BT, Chan RK. Reverse posterior interosseous flap for defects of the dorsal ulnar wrist using previously burned and recently grafted skin. Burns. 2016 Mar; 42(2):e24-30. PMID: 26652146.
    Citations:    Fields:    Translation:Humans
  30. Fletcher JL, Cancio LC, Sinha I, Leung KP, Renz EM, Chan RK. Inability to determine tissue health is main indication of allograft use in intermediate extent burns. Burns. 2015 Dec; 41(8):1862-1867. PMID: 26471053.
    Citations:    Fields:    Translation:Humans
  31. Caterson SA, Carty MJ, Helliwell LA, Hergrueter CA, Pribaz JJ, Sinha I. Evolving options for breast reconstruction. Curr Probl Surg. 2015 May; 52(5):192-224. PMID: 26058793.
    Citations: 1     Fields:    Translation:Humans
  32. Rahman N, Sinha I, Husain F, Shah A, Patel A. The incidence of burns among sex-trafficking victims in India. Yale J Biol Med. 2014 Sep; 87(3):263-7. PMID: 25191142.
    Citations:    Fields:    Translation:Humans
  33. Sinha I, Sinha-Hikim AP, Wagers AJ, Sinha-Hikim I. Testosterone is essential for skeletal muscle growth in aged mice in a heterochronic parabiosis model. Cell Tissue Res. 2014 Sep; 357(3):815-21. PMID: 24859218.
    Citations: 8     Fields:    Translation:AnimalsCells
  34. Lau FH, Sinha I, Eriksson E. Abstract 41: High Efficiency Allows Plastic Surgery Trainees to Maintain Operative Experience within the Limitations of an 80-Hour Work Week. Plast Reconstr Surg. 2014 Apr; 133(4 Suppl):1005. PMID: 24675334.
    Citations:    
  35. Castiglioni A, Hettmer S, Lynes MD, Rao TN, Tchessalova D, Sinha I, Lee BT, Tseng YH, Wagers AJ. Isolation of progenitors that exhibit myogenic/osteogenic bipotency in vitro by fluorescence-activated cell sorting from human fetal muscle. Stem Cell Reports. 2014 Jan 14; 2(1):92-106. PMID: 24678452.
    Citations: 17     Fields:    Translation:HumansAnimalsCells
  36. Castiglioni A, Hettmer S, Lynes MD, Rao TN, Tchessalova D, Sinha I, Lee BT, Tseng YH, Wagers AJ. Isolation of Progenitors that Exhibit Myogenic/Osteogenic Bipotency In Vitro by Fluorescence-Activated Cell Sorting from Human Fetal Muscle. Stem Cell Reports. 2014 Jan 14; 2(1):92-106. PMID: 28039752.
    Citations:    
  37. Sinha I, Pomahac B. Split rejection in vascularized composite allotransplantation. Eplasty. 2013 Oct 08; 13:e53. PMID: 24244785.
    Citations: 2     
  38. Chun YS, Verma K, Sinha I, Rosen H, Hergrueter C, Wong J, Pribaz JJ. Impact of prior ipsilateral chest wall radiation on pedicled TRAM flap breast reconstruction. Ann Plast Surg. 2013 Jul; 71(1):16-9. PMID: 23123615.
    Citations: 3     Fields:    Translation:Humans
  39. Patel A, Sawh-Martinez RF, Sinha I, Watkins JF, Magee WP, Persing JA. Establishing sustainable international burn missions: lessons from India. Ann Plast Surg. 2013 Jul; 71(1):31-3. PMID: 23788123.
    Citations: 2     Fields:    Translation:Humans
  40. Kim FS, Tran HH, Sinha I, Patel A, Nelson RA, Pandya AN, Keswani S, Watkins JF. Experience with corrective surgery for postburn contractures in Mumbai, India. J Burn Care Res. 2012 May-Jun; 33(3):e120-6. PMID: 22210060.
    Citations: 3     Fields:    Translation:Humans
  41. Sinha I, Patel A, Kim FS, Maccorkle ML, Watkins JF. Comic books can educate children about burn safety in developing countries. J Burn Care Res. 2011 Jul-Aug; 32(4):e112-7. PMID: 21593680.
    Citations: 6     Fields:    Translation:Humans
  42. Pomahac B, Nowinski D, Diaz-Siso JR, Bueno EM, Talbot SG, Sinha I, Westvik TS, Vyas R, Singhal D. Face transplantation. Curr Probl Surg. 2011 May; 48(5):293-357. PMID: 21463717.
    Citations: 12     Fields:    Translation:Humans
  43. Patel A, Sinha I, McRae M, Broer N, Watkins J, Persing JA. The role of academic plastic surgery institutions in addressing the global burden of surgical disease. Plast Reconstr Surg. 2011 Feb; 127(2):1019-20. PMID: 21285845.
    Citations: 3     Fields:    Translation:Humans
  44. Chun YS, Sinha I, Turko A, Yueh JH, Lipsitz S, Pribaz JJ, Lee BT. Comparison of morbidity, functional outcome, and satisfaction following bilateral TRAM versus bilateral DIEP flap breast reconstruction. Plast Reconstr Surg. 2010 Oct; 126(4):1133-41. PMID: 20555301.
    Citations: 9     Fields:    Translation:Humans
  45. Patel A, McRae M, McRae M, Sinha I, Persing J. Plastic surgery during natural disasters: lessons from Haiti. Plast Reconstr Surg. 2010 Aug; 126(2):111e. PMID: 20679815.
    Citations: 1     Fields:    Translation:Humans
  46. Chun YS, Sinha I, Turko A, Lipsitz S, Pribaz JJ. Outcomes and patient satisfaction following breast reconstruction with bilateral pedicled TRAM flaps in 105 consecutive patients. Plast Reconstr Surg. 2010 Jan; 125(1):1-9. PMID: 19910856.
    Citations: 7     Fields:    Translation:Humans
  47. Kovacheva EL, Hikim AP, Shen R, Sinha I, Sinha-Hikim I. Testosterone supplementation reverses sarcopenia in aging through regulation of myostatin, c-Jun NH2-terminal kinase, Notch, and Akt signaling pathways. Endocrinology. 2010 Feb; 151(2):628-38. PMID: 20022929.
    Citations: 36     Fields:    Translation:HumansAnimalsCells
  48. Theman TA, Hartzell TL, Sinha I, Polson K, Morgan J, Demetri GD, Orgill DP, George S. Recognition of a new chemotherapeutic vesicant: trabectedin (ecteinascidin-743) extravasation with skin and soft tissue damage. J Clin Oncol. 2009 Nov 20; 27(33):e198-200. PMID: 19805684.
    Citations: 8     Fields:    Translation:Humans
  49. Sinha I, Pearce CG, Cho BS, Hannawa KK, Roelofs KJ, Stanley JC, Henke PK, Upchurch GR. Differential regulation of the superoxide dismutase family in experimental aortic aneurysms and rat aortic explants. J Surg Res. 2007 Apr; 138(2):156-62. PMID: 17196988.
    Citations: 3     Fields:    Translation:AnimalsCells
  50. Hannawa KK, Cho BS, Sinha I, Roelofs KJ, Myers DD, Wakefield TJ, Stanley JC, Henke PK, Upchurch GR. Attenuation of experimental aortic aneurysm formation in P-selectin knockout mice. Ann N Y Acad Sci. 2006 Nov; 1085:353-9. PMID: 17182955.
    Citations: 8     Fields:    Translation:Animals
  51. Sinha I, Cho BS, Roelofs KJ, Stanley JC, Henke PK, Upchurch GR. Female gender attenuates cytokine and chemokine expression and leukocyte recruitment in experimental rodent abdominal aortic aneurysms. Ann N Y Acad Sci. 2006 Nov; 1085:367-79. PMID: 17182958.
    Citations: 22     Fields:    Translation:AnimalsCells
  52. Sinha I, Bethi S, Cronin P, Williams DM, Roelofs K, Ailawadi G, Henke PK, Eagleton MJ, Deeb GM, Patel HJ, Berguer R, Stanley JC, Upchurch GR. A biologic basis for asymmetric growth in descending thoracic aortic aneurysms: a role for matrix metalloproteinase 9 and 2. J Vasc Surg. 2006 Feb; 43(2):342-8. PMID: 16476613.
    Citations: 11     Fields:    Translation:Humans
  53. Sinha I, Hannawa KK, Ailawadi G, Woodrum DT, Ford JW, Henke PK, Stanley JC, Eagleton MJ, Upchurch GR. The nitric oxide donor DETA-NONOate decreases matrix metalloproteinase-9 expression and activity in rat aortic smooth muscle and abdominal aortic explants. Ann Vasc Surg. 2006 Jan; 20(1):92-8. PMID: 16378139.
    Citations: 5     Fields:    Translation:AnimalsCells
  54. Sinha I, Sinha-Hikim AP, Hannawa KK, Henke PK, Eagleton MJ, Stanley JC, Upchurch GR. Mitochondrial-dependent apoptosis in experimental rodent abdominal aortic aneurysms. Surgery. 2005 Oct; 138(4):806-11. PMID: 16269312.
    Citations: 5     Fields:    Translation:AnimalsCells
  55. Woodrum DT, Ford JW, Ailawadi G, Pearce CG, Sinha I, Eagleton MJ, Henke PK, Stanley JC, Upchurch GR. Gender differences in rat aortic smooth muscle cell matrix metalloproteinase-9. J Am Coll Surg. 2005 Sep; 201(3):398-404. PMID: 16125073.
    Citations: 6     Fields:    Translation:AnimalsCells
  56. Eliason JL, Hannawa KK, Ailawadi G, Sinha I, Ford JW, Deogracias MP, Roelofs KJ, Woodrum DT, Ennis TL, Henke PK, Stanley JC, Thompson RW, Upchurch GR. Neutrophil depletion inhibits experimental abdominal aortic aneurysm formation. Circulation. 2005 Jul 12; 112(2):232-40. PMID: 16009808.
    Citations: 58     Fields:    Translation:AnimalsCells
  57. Grigoryants V, Hannawa KK, Pearce CG, Sinha I, Roelofs KJ, Ailawadi G, Deatrick KB, Woodrum DT, Cho BS, Henke PK, Stanley JC, Eagleton MJ, Upchurch GR. Tamoxifen up-regulates catalase production, inhibits vessel wall neutrophil infiltration, and attenuates development of experimental abdominal aortic aneurysms. J Vasc Surg. 2005 Jan; 41(1):108-14. PMID: 15696052.
    Citations: 13     Fields:    Translation:AnimalsCells
  58. Ailawadi G, Eliason JL, Roelofs KJ, Sinha I, Hannawa KK, Kaldjian EP, Lu G, Henke PK, Stanley JC, Weiss SJ, Thompson RW, Upchurch GR. Gender differences in experimental aortic aneurysm formation. Arterioscler Thromb Vasc Biol. 2004 Nov; 24(11):2116-22. PMID: 15331435.
    Citations: 36     Fields:    Translation:AnimalsCells
  59. Sinha I, Hannawa KK, Eliason JL, Ailawadi G, Deogracias MP, Bethi S, Ford JW, Roelofs KJ, Grigoryants V, Henke PK, Stanley JC, Upchurch GR. Early MT-1 MMP expression following elastase exposure is associated with increased cleaved MMP-2 activity in experimental rodent aortic aneurysms. Surgery. 2004 Aug; 136(2):176-82. PMID: 15300177.
    Citations: 11     Fields:    Translation:Animals
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.