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Joan Whitten Miller, M.D.

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Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Laíns I, Duarte D, Barros AS, Martins AS, Carneiro TJ, Gil JQ, Miller JB, Marques M, Mesquita TS, Barreto P, Kim IK, da Luz Cachulo M, Vavvas DG, Carreira IM, Murta JN, Silva R, Miller JW, Husain D, Gil AM. Urine Nuclear Magnetic Resonance (NMR) Metabolomics in Age-Related Macular Degeneration. J Proteome Res. 2019 Mar 01; 18(3):1278-1288. PMID: 30672297.
    Citations:    Fields:    
  2. Roh M, Laíns I, Shin HJ, Park DH, Mach S, Vavvas DG, Kim IK, Miller JW, Husain D, Miller JB. Microperimetry in age-related macular degeneration: association with macular morphology assessed by optical coherence tomography. Br J Ophthalmol. 2019 Feb 01. PMID: 30709810.
    Citations:    Fields:    
  3. Tsoka P, Barbisan PR, Kataoka K, Chen XN, Tian B, Bouzika P, Miller JW, Paschalis EI, Vavvas DG. NLRP3 inflammasome in NMDA-induced retinal excitotoxicity. Exp Eye Res. 2019 Jan 29; 181:136-144. PMID: 30707890.
    Citations:    Fields:    
  4. Al-Moujahed A, Tian B, Efstathiou NE, Konstantinou EK, Hoang M, Lin H, Miller JW, Vavvas DG. Receptor interacting protein kinase 3 (RIP3) regulates iPSCs generation through modulating cell cycle progression genes. Stem Cell Res. 2019 Mar; 35:101387. PMID: 30703581.
    Citations:    Fields:    
  5. Mukai R, Park DH, Okunuki Y, Hasegawa E, Klokman G, Kim CB, Krishnan A, Gregory-Ksander M, Husain D, Miller JW, Connor KM. Mouse model of ocular hypertension with retinal ganglion cell degeneration. PLoS One. 2019; 14(1):e0208713. PMID: 30640920.
    Citations:    Fields:    
  6. Wang JC, Laíns I, Oellers P, Kim IK, Miller JW, Miller JB. Choroidal thickness and vascular density in macular telangiectasia type 2 using enface swept-source optical coherence tomography. Br J Ophthalmol. 2019 Jan 02. PMID: 30602449.
    Citations:    Fields:    
  7. Wang JC, Laíns I, Silverman RF, Sobrin L, Vavvas DG, Miller JW, Miller JB. Visualization of Choriocapillaris and Choroidal Vasculature in Healthy Eyes With En Face Swept-Source Optical Coherence Tomography Versus Angiography. Transl Vis Sci Technol. 2018 Nov; 7(6):25. PMID: 30598856.
    Citations:    
  8. Laíns I, Gantner M, Murinello S, Lasky-Su JA, Miller JW, Friedlander M, Husain D. Metabolomics in the study of retinal health and disease. Prog Retin Eye Res. 2018 Nov 10. PMID: 30423446.
    Citations:    Fields:    
  9. Borboli-Gerogiannis S, Jeng-Miller KW, Koulisis N, Moustafa GA, Chang KK, Chen SH, Gardiner MF, Greenstein SH, Luo Z, Chen TC, Loewenstein JI, Miller JW, Haviland MJ, Kloek CE. A Comprehensive Surgical Curriculum Reduced Intra-operative Complication Rates of Resident-performed Cataract Surgeries. J Surg Educ. 2019 Jan - Feb; 76(1):150-157. PMID: 30131282.
    Citations:    Fields:    
  10. Miller JW, Vandenberghe LH. Breaking and Sealing Barriers in Retinal Gene Therapy. Mol Ther. 2018 Sep 05; 26(9):2081-2082. PMID: 30107998.
    Citations:    Fields:    
  11. Laíns I, Kelly RS, Miller JB, Vavvas DG, Kim IK, Lasky-Su J, Miller JW, Husain D. Reply. Ophthalmology. 2018 Jul; 125(7):e46-e47. PMID: 29935675.
    Citations:    Fields:    
  12. Okunuki Y, Mukai R, Pearsall EA, Klokman G, Husain D, Park DH, Korobkina E, Weiner HL, Butovsky O, Ksander BR, Miller JW, Connor KM. Microglia inhibit photoreceptor cell death and regulate immune cell infiltration in response to retinal detachment. Proc Natl Acad Sci U S A. 2018 07 03; 115(27):E6264-E6273. PMID: 29915052.
    Citations: 1     Fields:    Translation:AnimalsCells
  13. Laíns I, Miller JB, Mukai R, Mach S, Vavvas D, Kim IK, Miller JW, Husain D. HEALTH CONDITIONS LINKED TO AGE-RELATED MACULAR DEGENERATION ASSOCIATED WITH DARK ADAPTATION. Retina. 2018 Jun; 38(6):1145-1155. PMID: 28452839.
    Citations:    Fields:    Translation:Humans
  14. Roh M, Selivanova A, Shin HJ, Miller JW, Jackson ML. Visual acuity and contrast sensitivity are two important factors affecting vision-related quality of life in advanced age-related macular degeneration. PLoS One. 2018; 13(5):e0196481. PMID: 29746512.
    Citations:    Fields:    Translation:HumansCells
  15. Diaz JD, Wang JC, Oellers P, Lains I, Sobrin L, Husain D, Miller JW, Vavvas DG, Miller JB. Imaging the Deep Choroidal Vasculature Using Spectral Domain and Swept Source Optical Coherence Tomography Angiography. J Vitreoretin Dis. 2018 May-Jun; 2(3):146-154. PMID: 29930992.
    Citations:    
  16. Vavvas DG, Dryja TP, Wilson ME, Olsen TW, Shah A, Jurkunas U, Pineda R, Poulaki V, Palioura S, Veldman P, Moreno-Montañés J, Pinazo-Duran MD, Pastor JC, Tsilimbaris M, Rhee D, Colby K, Hunter DG, Thanos S, Sakamoto T, Pasquale LR, Miller JW, VanderVeen D, Lambert SR. Lens regeneration in children. Nature. 2018 04 04; 556(7699):E2-E3. PMID: 29620729.
    Citations: 1     Fields:    
  17. Laíns I, Park DH, Mukai R, Silverman R, Oellers P, Mach S, Kim IK, Vavvas DG, Miller JW, Miller JB, Husain D. Peripheral Changes Associated With Delayed Dark Adaptation in Age-related Macular Degeneration. Am J Ophthalmol. 2018 Jun; 190:113-124. PMID: 29621510.
    Citations:    Fields:    
  18. Ung C, Laíns I, Silverman RF, Woods R, Lane AM, Papakostas TD, Husain D, Miller JW, Gragoudas ES, Kim IK, Miller JB. Evaluation of choroidal lesions with swept-source optical coherence tomography. Br J Ophthalmol. 2019 Jan; 103(1):88-93. PMID: 29605814.
    Citations:    Fields:    
  19. Perlman EM, Greenberg PB, Browning D, Friday RP, Miller JW. Solving the Hydroxychloroquine Dosing Dilemma With a Smartphone App. JAMA Ophthalmol. 2018 Feb 01; 136(2):218-219. PMID: 29302689.
    Citations: 1     Fields:    
  20. Kosmidou C, Efstathiou NE, Hoang MV, Notomi S, Konstantinou EK, Hirano M, Takahashi K, Maidana DE, Tsoka P, Young L, Gragoudas ES, Olsen TW, Morizane Y, Miller JW, Vavvas DG. Issues with the Specificity of Immunological Reagents for NLRP3: Implications for Age-related Macular Degeneration. Sci Rep. 2018 01 11; 8(1):461. PMID: 29323137.
    Citations: 3     Fields:    Translation:HumansAnimalsCells
  21. Laíns I, Talcott KE, Santos AR, Marques JH, Gil P, Gil J, Figueira J, Husain D, Kim IK, Miller JW, Silva R, Miller JB. CHOROIDAL THICKNESS IN DIABETIC RETINOPATHY ASSESSED WITH SWEPT-SOURCE OPTICAL COHERENCE TOMOGRAPHY. Retina. 2018 Jan; 38(1):173-182. PMID: 28196053.
    Citations: 3     Fields:    Translation:Humans
  22. Chung EJ, Efstathiou NE, Konstantinou EK, Maidana DE, Miller JW, Young LH, Vavvas DG. AICAR suppresses TNF-a-induced complement factor B in RPE cells. Sci Rep. 2017 Dec 15; 7(1):17651. PMID: 29247196.
    Citations:    Fields:    
  23. Oellers P, Laíns I, Mach S, Garas S, Kim IK, Vavvas DG, Miller JW, Husain D, Miller JB. Novel grid combined with peripheral distortion correction for ultra-widefield image grading of age-related macular degeneration. Clin Ophthalmol. 2017; 11:1967-1974. PMID: 29184386.
    Citations:    
  24. Wang JC, Laíns I, Providência J, Armstrong GW, Santos AR, Gil P, Gil J, Talcott KE, Marques JH, Figueira J, Vavvas DG, Kim IK, Miller JW, Husain D, Silva R, Miller JB. Diabetic Choroidopathy: Choroidal Vascular Density and Volume in Diabetic Retinopathy With Swept-Source Optical Coherence Tomography. Am J Ophthalmol. 2017 Dec; 184:75-83. PMID: 28988899.
    Citations: 1     Fields:    Translation:Humans
  25. Laíns I, Kelly RS, Miller JB, Silva R, Vavvas DG, Kim IK, Murta JN, Lasky-Su J, Miller JW, Husain D. Human Plasma Metabolomics Study across All Stages of Age-Related Macular Degeneration Identifies Potential Lipid Biomarkers. Ophthalmology. 2018 02; 125(2):245-254. PMID: 28916333.
    Citations: 3     Fields:    Translation:Humans
  26. Hasegawa E, Inafuku S, Mulki L, Okunuki Y, Yanai R, Smith KE, Kim CB, Klokman G, Bielenberg DR, Puli N, Falck JR, Husain D, Miller JW, Edin ML, Zeldin DC, Lee KSS, Hammock BD, Schunck WH, Connor KM. Cytochrome P450 monooxygenase lipid metabolites are significant second messengers in the resolution of choroidal neovascularization. Proc Natl Acad Sci U S A. 2017 09 05; 114(36):E7545-E7553. PMID: 28827330.
    Citations:    Fields:    Translation:AnimalsCells
  27. Al-Moujahed A, Brodowska K, Stryjewski TP, Efstathiou NE, Vasilikos I, Cichy J, Miller JW, Gragoudas E, Vavvas DG. Verteporfin inhibits growth of human glioma in vitro without light activation. Sci Rep. 2017 08 08; 7(1):7602. PMID: 28790340.
    Citations: 8     Fields:    
  28. Laíns I, Wang J, Providência J, Mach S, Gil P, Gil J, Marques M, Armstrong G, Garas S, Barreto P, Kim IK, Vavvas DG, Miller JW, Husain D, Silva R, Miller JB. Choroidal Changes Associated With Subretinal Drusenoid Deposits in Age-related Macular Degeneration Using Swept-source Optical Coherence Tomography. Am J Ophthalmol. 2017 Aug; 180:55-63. PMID: 28579063.
    Citations:    Fields:    Translation:Humans
  29. Tian B, Al-Moujahed A, Bouzika P, Hu Y, Notomi S, Tsoka P, Miller JW, Lin H, Vavvas DG. Atorvastatin Promotes Phagocytosis and Attenuates Pro-Inflammatory Response in Human Retinal Pigment Epithelial Cells. Sci Rep. 2017 05 24; 7(1):2329. PMID: 28539592.
    Citations: 1     Fields:    Translation:HumansCells
  30. Laíns I, Duarte D, Barros AS, Martins AS, Gil J, Miller JB, Marques M, Mesquita T, Kim IK, Cachulo MDL, Vavvas D, Carreira IM, Murta JN, Silva R, Miller JW, Husain D, Gil AM. Human plasma metabolomics in age-related macular degeneration (AMD) using nuclear magnetic resonance spectroscopy. PLoS One. 2017; 12(5):e0177749. PMID: 28542375.
    Citations: 3     Fields:    Translation:Humans
  31. Laíns I, Miller JB, Park DH, Tsikata E, Davoudi S, Rahmani S, Pierce J, Silva R, Chen TC, Kim IK, Vavvas D, Miller JW, Husain D. Structural Changes Associated with Delayed Dark Adaptation in Age-Related Macular Degeneration. Ophthalmology. 2017 09; 124(9):1340-1352. PMID: 28501377.
    Citations: 2     Fields:    Translation:Humans
  32. Konstantinou EK, Notomi S, Kosmidou C, Brodowska K, Al-Moujahed A, Nicolaou F, Tsoka P, Gragoudas E, Miller JW, Young LH, Vavvas DG. Verteporfin-induced formation of protein cross-linked oligomers and high molecular weight complexes is mediated by light and leads to cell toxicity. Sci Rep. 2017 Apr 21; 7:46581. PMID: 28429726.
    Citations: 8     Fields:    
  33. Levin LA, Miller JW, Zack DJ, Friedlander M, Smith LEH. Special Commentary: Early Clinical Development of Cell Replacement Therapy: Considerations for the National Eye Institute Audacious Goals Initiative. Ophthalmology. 2017 07; 124(7):926-934. PMID: 28365209.
    Citations: 1     Fields:    Translation:HumansAnimals
  34. Tsikata E, Laíns I, Gil J, Marques M, Brown K, Mesquita T, Melo P, da Luz Cachulo M, Kim IK, Vavvas D, Murta JN, Miller JB, Silva R, Miller JW, Chen TC, Husain D. Automated Brightness and Contrast Adjustment of Color Fundus Photographs for the Grading of Age-Related Macular Degeneration. Transl Vis Sci Technol. 2017 Mar; 6(2):3. PMID: 28316876.
    Citations: 1     
  35. Miller JW, Bagheri S, Vavvas DG. Advances in Age-related Macular Degeneration Understanding and Therapy. US Ophthalmic Rev. 2017; 10(2):119-130. PMID: 29142592.
    Citations:    
  36. Miller JW. Beyond VEGF-The Weisenfeld Lecture. Invest Ophthalmol Vis Sci. 2016 12 01; 57(15):6911-6918. PMID: 28027565.
    Citations: 1     Fields:    Translation:HumansAnimals
  37. Tian B, Maidana DE, Dib B, Miller JB, Bouzika P, Miller JW, Vavvas DG, Lin H. miR-17-3p Exacerbates Oxidative Damage in Human Retinal Pigment Epithelial Cells. PLoS One. 2016; 11(8):e0160887. PMID: 27505139; PMCID: PMC4978424.
    Citations: 2     Fields:    Translation:Humans
  38. Cho H, Shin YU, Siegel NH, Yu HG, Sobrin L, Patel A, Durand ML, Miller JW, Husain D. Endogenous Endophthalmitis in the American and Korean Population: An 8-year Retrospective Study. Ocul Immunol Inflamm. 2018; 26(4):496-503. PMID: 27459423.
    Citations: 4     Fields:    Translation:HumansAnimalsCells
  39. Finn AP, Borboli-Gerogiannis S, Brauner S, Peggy Chang HY, Chen S, Gardiner M, Greenstein SH, Kloek C, Miller JW, Chen TC. Assessing Resident Cataract Surgery Outcomes Using Medicare Physician Quality Reporting System Measures. J Surg Educ. 2016 Sep-Oct; 73(5):774-9. PMID: 27211876.
    Citations: 1     Fields:    Translation:Humans
  40. Mantopoulos D, Bouzika P, Tsakris A, Pawlyk BS, Sandberg MA, Miller JW, Rizzo Iii JF, Vavvas DG, Cestari DM. An Experimental Animal Model of Photodynamic Optic Nerve Head Injury (PONHI). Curr Eye Res. 2016 11; 41(11):1498-1506. PMID: 27158920.
    Citations:    Fields:    Translation:AnimalsCells
  41. Miller JW. VEGF: From Discovery to Therapy: The Champalimaud Award Lecture. Transl Vis Sci Technol. 2016 Mar; 5(2):9. PMID: 26981331.
    Citations: 6     
  42. Laíns I, Bartosch C, Mondim V, Healy B, Kim IK, Husain D, Miller JW. Second Primary Neoplasms in Patients With Uveal Melanoma: A SEER Database Analysis. Am J Ophthalmol. 2016 05; 165:54-64. PMID: 26940164.
    Citations: 1     Fields:    Translation:Humans
  43. Vavvas DG, Daniels AB, Kapsala ZG, Goldfarb JW, Ganotakis E, Loewenstein JI, Young LH, Gragoudas ES, Eliott D, Kim IK, Tsilimbaris MK, Miller JW. Regression of Some High-risk Features of Age-related Macular Degeneration (AMD) in Patients Receiving Intensive Statin Treatment. EBioMedicine. 2016 Mar; 5:198-203. PMID: 27077128; PMCID: PMC4816836.
    Citations: 14     Fields:    Translation:HumansCTClinical Trials
  44. Kumase F, Takeuchi K, Morizane Y, Suzuki J, Matsumoto H, Kataoka K, Al-Moujahed A, Maidana DE, Miller JW, Vavvas DG. AMPK-Activated Protein Kinase Suppresses Ccr2 Expression by Inhibiting the NF-?B Pathway in RAW264.7 Macrophages. PLoS One. 2016; 11(1):e0147279. PMID: 26799633.
    Citations: 2     Fields:    Translation:AnimalsCells
  45. Lin H, Yue Y, Maidana DE, Bouzika P, Atik A, Matsumoto H, Miller JW, Vavvas DG. Drug Delivery Nanoparticles: Toxicity Comparison in Retinal Pigment Epithelium and Retinal Vascular Endothelial Cells. Semin Ophthalmol. 2016; 31(1-2):1-9. PMID: 26959123.
    Citations: 1     Fields:    Translation:HumansCells
  46. Maidana DE, Tsoka P, Tian B, Dib B, Matsumoto H, Kataoka K, Lin H, Miller JW, Vavvas DG. A Novel ImageJ Macro for Automated Cell Death Quantitation in the Retina. Invest Ophthalmol Vis Sci. 2015 Oct; 56(11):6701-8. PMID: 26469755; PMCID: PMC4611955.
    Citations: 2     Fields:    Translation:Animals
  47. Dib B, Lin H, Maidana DE, Tian B, Miller JB, Bouzika P, Miller JW, Vavvas DG. Mitochondrial DNA has a pro-inflammatory role in AMD. Biochim Biophys Acta. 2015 Nov; 1853(11 Pt A):2897-906. PMID: 26305120.
    Citations: 6     Fields:    Translation:HumansCells
  48. Sweigard JH, Matsumoto H, Smith KE, Kim LA, Paschalis EI, Okonuki Y, Castillejos A, Kataoka K, Hasegawa E, Yanai R, Husain D, Lambris JD, Vavvas D, Miller JW, Connor KM. Inhibition of the alternative complement pathway preserves photoreceptors after retinal injury. Sci Transl Med. 2015 Jul 22; 7(297):297ra116. PMID: 26203084; PMCID: PMC4779952.
    Citations: 9     Fields:    Translation:HumansAnimalsCells
  49. Morrison MA, Magalhaes TR, Ramke J, Smith SE, Ennis S, Simpson CL, Portas L, Murgia F, Ahn J, Dardenne C, Mayne K, Robinson R, Morgan DJ, Brian G, Lee L, Woo SJ, Zacharaki F, Tsironi EE, Miller JW, Kim IK, Park KH, Bailey-Wilson JE, Farrer LA, Stambolian D, DeAngelis MM. Ancestry of the Timorese: age-related macular degeneration associated genotype and allele sharing among human populations from throughout the world. Front Genet. 2015; 6:238. PMID: 26217379; PMCID: PMC4496576.
    Citations: 1     
  50. Chen TC, Schein OD, Miller JW. Sentinel Events, Serious Reportable Events, and Root Cause Analysis. JAMA Ophthalmol. 2015 Jun; 133(6):631-2. PMID: 25742139.
    Citations:    Fields:    Translation:HumansPHPublic Health
  51. Yonekawa Y, Miller JW, Kim IK. Age-Related Macular Degeneration: Advances in Management and Diagnosis. J Clin Med. 2015 Feb 12; 4(2):343-59. PMID: 26239130; PMCID: PMC4470128.
    Citations: 18     
  52. Brodowska K, Theodoropoulou S, Meyer Zu Hörste M, Paschalis EI, Takeuchi K, Scott G, Ramsey DJ, Kiernan E, Hoang M, Cichy J, Miller JW, Gragoudas ES, Vavvas DG. Effects of metformin on retinoblastoma growth in vitro and in vivo. Int J Oncol. 2014 Dec; 45(6):2311-24. PMID: 25215935; PMCID: PMC4215581.
    Citations: 5     Fields:    Translation:HumansAnimals
  53. Hasegawa E, Sweigard H, Husain D, Olivares AM, Chang B, Smith KE, Birsner AE, D'Amato RJ, Michaud NA, Han Y, Vavvas DG, Miller JW, Haider NB, Connor KM. Characterization of a spontaneous retinal neovascular mouse model. PLoS One. 2014; 9(9):e106507. PMID: 25188381; PMCID: PMC4154693.
    Citations: 8     Fields:    Translation:Animals
  54. Hu Y, Lin H, Dib B, Atik A, Bouzika P, Lin C, Yan Y, Tang S, Miller JW, Vavvas DG. Cholesterol crystals induce inflammatory cytokines expression in a human retinal pigment epithelium cell line by activating the NF-?B pathway. Discov Med. 2014 Jul-Aug; 18(97):7-14. PMID: 25091484.
    Citations: 2     Fields:    Translation:HumansCells
  55. Yanai R, Mulki L, Hasegawa E, Takeuchi K, Sweigard H, Suzuki J, Gaissert P, Vavvas DG, Sonoda KH, Rothe M, Schunck WH, Miller JW, Connor KM. Cytochrome P450-generated metabolites derived from ?-3 fatty acids attenuate neovascularization. Proc Natl Acad Sci U S A. 2014 Jul 01; 111(26):9603-8. PMID: 24979774; PMCID: PMC4084420.
    Citations: 13     Fields:    Translation:Animals
  56. Matsumoto H, Kataoka K, Tsoka P, Connor KM, Miller JW, Vavvas DG. Strain difference in photoreceptor cell death after retinal detachment in mice. Invest Ophthalmol Vis Sci. 2014 May 22; 55(7):4165-74. PMID: 24854853; PMCID: PMC4089419.
    Citations: 15     Fields:    Translation:AnimalsCells
  57. Yonekawa Y, Hacker HD, Lehman RE, Beal CJ, Veldman PB, Vyas NM, Shah AS, Wu D, Eliott D, Gardiner MF, Kuperwaser MC, Rosa RH, Ramsey JE, Miller JW, Mazzoli RA, Lawrence MG, Arroyo JG. Ocular blast injuries in mass-casualty incidents: the marathon bombing in Boston, Massachusetts, and the fertilizer plant explosion in West, Texas. Ophthalmology. 2014 Sep; 121(9):1670-6.e1. PMID: 24841363.
    Citations: 4     Fields:    Translation:Humans
  58. Brodowska K, Al-Moujahed A, Marmalidou A, Meyer Zu Horste M, Cichy J, Miller JW, Gragoudas E, Vavvas DG. The clinically used photosensitizer Verteporfin (VP) inhibits YAP-TEAD and human retinoblastoma cell growth in vitro without light activation. Exp Eye Res. 2014 Jul; 124:67-73. PMID: 24837142; PMCID: PMC4135181.
    Citations: 40     Fields:    Translation:HumansCells
  59. Chen L, Kim IK, Lane AM, Gauthier D, Munzenrider JE, Gragoudas ES, Miller JW. Proton beam irradiation for non-AMD CNV: 2-year results of a randomised clinical trial. Br J Ophthalmol. 2014 Sep; 98(9):1212-7. PMID: 24820046.
    Citations: 1     Fields:    Translation:HumansPHPublic Health
  60. Owen LA, Morrison MA, Ahn J, Woo SJ, Sato H, Robinson R, Morgan DJ, Zacharaki F, Simeonova M, Uehara H, Chakravarthy U, Hogg RE, Ambati BK, Kotoula M, Baehr W, Haider NB, Silvestri G, Miller JW, Tsironi EE, Farrer LA, Kim IK, Park KH, DeAngelis MM. FLT1 genetic variation predisposes to neovascular AMD in ethnically diverse populations and alters systemic FLT1 expression. Invest Ophthalmol Vis Sci. 2014 May 08; 55(6):3543-54. PMID: 24812550; PMCID: PMC4073997.
    Citations: 4     Fields:    Translation:HumansAnimals
  61. Al-Moujahed A, Nicolaou F, Brodowska K, Papakostas TD, Marmalidou A, Ksander BR, Miller JW, Gragoudas E, Vavvas DG. Uveal melanoma cell growth is inhibited by aminoimidazole carboxamide ribonucleotide (AICAR) partially through activation of AMP-dependent kinase. Invest Ophthalmol Vis Sci. 2014 Apr 29; 55(7):4175-85. PMID: 24781943; PMCID: PMC4089421.
    Citations:    Fields:    Translation:HumansCells
  62. Takeuchi K, Yanai R, Kumase F, Morizane Y, Suzuki J, Kayama M, Brodowska K, Nakazawa M, Miller JW, Connor KM, Vavvas DG. EGF-like-domain-7 is required for VEGF-induced Akt/ERK activation and vascular tube formation in an ex vivo angiogenesis assay. PLoS One. 2014; 9(3):e91849. PMID: 24647208; PMCID: PMC3960138.
    Citations: 7     Fields:    Translation:AnimalsCells
  63. Wiggs JL, Pawlyk B, Connolly E, Adamian M, Miller JW, Pasquale LR, Haddadin RI, Grosskreutz CL, Rhee DJ, Li T. Disruption of the blood-aqueous barrier and lens abnormalities in mice lacking lysyl oxidase-like 1 (LOXL1). Invest Ophthalmol Vis Sci. 2014 Feb 10; 55(2):856-64. PMID: 24425853; PMCID: PMC3920824.
    Citations: 11     Fields:    Translation:Animals
  64. Dana R, Miller JW. On the edge: the clinician-scientist in ophthalmology. JAMA Ophthalmol. 2013 Nov; 131(11):1401-2. PMID: 24077531.
    Citations: 1     Fields:    Translation:Humans
  65. Miller JW. The Harvard angiogenesis story. Surv Ophthalmol. 2014 May-Jun; 59(3):361-4. PMID: 24138892.
    Citations:    Fields:    Translation:Humans
  66. Matsumoto H, Miller JW, Vavvas DG. Retinal detachment model in rodents by subretinal injection of sodium hyaluronate. J Vis Exp. 2013 Sep 11; (79). PMID: 24056325; PMCID: PMC3864357.
    Citations: 11     Fields:    Translation:Animals
  67. Murakami Y, Notomi S, Hisatomi T, Nakazawa T, Ishibashi T, Miller JW, Vavvas DG. Photoreceptor cell death and rescue in retinal detachment and degenerations. Prog Retin Eye Res. 2013 Nov; 37:114-40. PMID: 23994436; PMCID: PMC3871865.
    Citations: 30     Fields:    Translation:HumansAnimalsCells
  68. Takeuchi K, Morizane Y, Kamami-Levy C, Suzuki J, Kayama M, Cai W, Miller JW, Vavvas DG. AMP-dependent kinase inhibits oxidative stress-induced caveolin-1 phosphorylation and endocytosis by suppressing the dissociation between c-Abl and Prdx1 proteins in endothelial cells. J Biol Chem. 2013 Jul 12; 288(28):20581-91. PMID: 23723070; PMCID: PMC3711322.
    Citations: 8     Fields:    Translation:HumansCells
  69. Yonekawa Y, Andreoli C, Miller JB, Loewenstein JI, Sobrin L, Eliott D, Vavvas DG, Miller JW, Kim IK. Conversion to aflibercept for chronic refractory or recurrent neovascular age-related macular degeneration. Am J Ophthalmol. 2013 Jul; 156(1):29-35.e2. PMID: 23668679.
    Citations: 53     Fields:    Translation:Humans
  70. Englander M, Chen TC, Paschalis EI, Miller JW, Kim IK. Intravitreal injections at the Massachusetts Eye and Ear Infirmary: analysis of treatment indications and postinjection endophthalmitis rates. Br J Ophthalmol. 2013 Apr; 97(4):460-5. PMID: 23390167.
    Citations: 15     Fields:    Translation:Humans
  71. Theodoropoulou S, Brodowska K, Kayama M, Morizane Y, Miller JW, Gragoudas ES, Vavvas DG. Aminoimidazole carboxamide ribonucleotide (AICAR) inhibits the growth of retinoblastoma in vivo by decreasing angiogenesis and inducing apoptosis. PLoS One. 2013; 8(1):e52852. PMID: 23300996; PMCID: PMC3536763.
    Citations: 16     Fields:    Translation:AnimalsCells
  72. Veldman PB, Miller JW. Subspecialties of ophthalmic practice. Int Ophthalmol Clin. 2013; 53(4):xi. PMID: 24088947.
    Citations:    Fields:    Translation:Humans
  73. Miller JW. Age-related macular degeneration revisited--piecing the puzzle: the LXIX Edward Jackson memorial lecture. Am J Ophthalmol. 2013 Jan; 155(1):1-35.e13. PMID: 23245386.
    Citations: 56     Fields:    Translation:Humans
  74. Miller JW, Le Couter J, Strauss EC, Ferrara N. Vascular endothelial growth factor a in intraocular vascular disease. Ophthalmology. 2013 Jan; 120(1):106-14. PMID: 23031671.
    Citations: 77     Fields:    Translation:Humans
  75. Murakami Y, Matsumoto H, Roh M, Suzuki J, Hisatomi T, Ikeda Y, Miller JW, Vavvas DG. Receptor interacting protein kinase mediates necrotic cone but not rod cell death in a mouse model of inherited degeneration. Proc Natl Acad Sci U S A. 2012 Sep 04; 109(36):14598-603. PMID: 22908283; PMCID: PMC3437885.
    Citations: 45     Fields:    Translation:AnimalsCells
  76. Roh M, Zhang Y, Murakami Y, Thanos A, Lee SC, Vavvas DG, Benowitz LI, Miller JW. Etanercept, a widely used inhibitor of tumor necrosis factor-a (TNF-a), prevents retinal ganglion cell loss in a rat model of glaucoma. PLoS One. 2012; 7(7):e40065. PMID: 22802951; PMCID: PMC3388998.
    Citations: 56     Fields:    Translation:AnimalsCells
  77. Suzuki J, Yoshimura T, Simeonova M, Takeuchi K, Murakami Y, Morizane Y, Miller JW, Sobrin L, Vavvas DG. Aminoimidazole carboxamide ribonucleotide ameliorates experimental autoimmune uveitis. Invest Ophthalmol Vis Sci. 2012 Jun 28; 53(7):4158-69. PMID: 22562518; PMCID: PMC3392008.
    Citations: 11     Fields:    Translation:AnimalsCells
  78. Hisatomi T, Nakao S, Murakami Y, Noda K, Nakazawa T, Notomi S, Connolly E, She H, Almulki L, Ito Y, Vavvas DG, Ishibashi T, Miller JW. The regulatory roles of apoptosis-inducing factor in the formation and regression processes of ocular neovascularization. Am J Pathol. 2012 Jul; 181(1):53-61. PMID: 22613025; PMCID: PMC3388154.
    Citations: 5     Fields:    Translation:AnimalsCells
  79. Thanos A, Morizane Y, Murakami Y, Giani A, Mantopoulos D, Kayama M, Roh MI, Michaud N, Pawlyk B, Sandberg M, Young LH, Miller JW, Vavvas DG. Evidence for baseline retinal pigment epithelium pathology in the Trp1-Cre mouse. Am J Pathol. 2012 May; 180(5):1917-27. PMID: 22429967; PMCID: PMC3349832.
    Citations: 15     Fields:    Translation:AnimalsCells
  80. Cohen SJ, Chan RV, Keegan M, Andreoli CM, Borenstein JT, Miller JW, Gragoudas ES. Evaluation of tissue interactions with mechanical elements of a transscleral drug delivery device. Pharmaceutics. 2012 Mar 12; 4(1):212-29. PMID: 24300189; PMCID: PMC3834904.
    Citations:    
  81. Sekiyama E, Saint-Geniez M, Yoneda K, Hisatomi T, Nakao S, Walshe TE, Maruyama K, Hafezi-Moghadam A, Miller JW, Kinoshita S, D'Amore PA. Heat treatment of retinal pigment epithelium induces production of elastic lamina components and antiangiogenic activity. FASEB J. 2012 Feb; 26(2):567-75. PMID: 22067481; PMCID: PMC4090388.
    Citations: 8     Fields:    Translation:HumansAnimalsCells
  82. Chen L, Miller JW, Vavvas D, Kim IK. Anti-vascular endothelial growth factor monotherapy versus combination treatment with photodynamic therapy for subfoveal choroidal neovascularization secondary to causes other than age-related macular degeneration. Retina. 2011 Nov; 31(10):2078-83. PMID: 21691258.
    Citations: 1     Fields:    Translation:Humans
  83. Jun G, Nicolaou M, Morrison MA, Buros J, Morgan DJ, Radeke MJ, Yonekawa Y, Tsironi EE, Kotoula MG, Zacharaki F, Mollema N, Yuan Y, Miller JW, Haider NB, Hageman GS, Kim IK, Schaumberg DA, Farrer LA, DeAngelis MM. Influence of ROBO1 and RORA on risk of age-related macular degeneration reveals genetically distinct phenotypes in disease pathophysiology. PLoS One. 2011; 6(10):e25775. PMID: 21998696; PMCID: PMC3188561.
    Citations: 10     Fields:    Translation:HumansAnimalsCells
  84. Morrison MA, Silveira AC, Huynh N, Jun G, Smith SE, Zacharaki F, Sato H, Loomis S, Andreoli MT, Adams SM, Radeke MJ, Jelcick AS, Yuan Y, Tsiloulis AN, Chatzoulis DZ, Silvestri G, Kotoula MG, Tsironi EE, Hollis BW, Chen R, Haider NB, Miller JW, Farrer LA, Hageman GS, Kim IK, Schaumberg DA, DeAngelis MM. Systems biology-based analysis implicates a novel role for vitamin D metabolism in the pathogenesis of age-related macular degeneration. Hum Genomics. 2011 Oct; 5(6):538-68. PMID: 22155603; PMCID: PMC3525248.
    Citations: 20     Fields:    Translation:Humans
  85. Mantopoulos D, Murakami Y, Comander J, Thanos A, Roh M, Miller JW, Vavvas DG. Tauroursodeoxycholic acid (TUDCA) protects photoreceptors from cell death after experimental retinal detachment. PLoS One. 2011; 6(9):e24245. PMID: 21961034; PMCID: PMC3178513.
    Citations: 22     Fields:    Translation:AnimalsCells
  86. Suzuki J, Manola A, Murakami Y, Morizane Y, Takeuchi K, Kayama M, Miller JW, Sobrin L, Vavvas DG. Inhibitory effect of aminoimidazole carboxamide ribonucleotide (AICAR) on endotoxin-induced uveitis in rats. Invest Ophthalmol Vis Sci. 2011 Aug 22; 52(9):6565-71. PMID: 21775660.
    Citations: 12     Fields:    Translation:AnimalsCells
  87. Giani A, Luiselli C, Esmaili DD, Salvetti P, Cigada M, Miller JW, Staurenghi G. Spectral-domain optical coherence tomography as an indicator of fluorescein angiography leakage from choroidal neovascularization. Invest Ophthalmol Vis Sci. 2011 Jul 29; 52(8):5579-86. PMID: 21693602.
    Citations: 11     Fields:    Translation:Humans
  88. Feehan M, Hartman J, Durante R, Morrison MA, Miller JW, Kim IK, DeAngelis MM. Identifying subtypes of patients with neovascular age-related macular degeneration by genotypic and cardiovascular risk characteristics. BMC Med Genet. 2011 Jun 17; 12:83. PMID: 21682878; PMCID: PMC3141628.
    Citations: 4     Fields:    Translation:HumansCells
  89. Giani A, Thanos A, Roh MI, Connolly E, Trichonas G, Kim I, Gragoudas E, Vavvas D, Miller JW. In vivo evaluation of laser-induced choroidal neovascularization using spectral-domain optical coherence tomography. Invest Ophthalmol Vis Sci. 2011 Jun 01; 52(6):3880-7. PMID: 21296820.
    Citations: 37     Fields:    Translation:Animals
  90. Roh MI, Murakami Y, Thanos A, Vavvas DG, Miller JW. Edaravone, an ROS scavenger, ameliorates photoreceptor cell death after experimental retinal detachment. Invest Ophthalmol Vis Sci. 2011 Jun 01; 52(6):3825-31. PMID: 21310909; PMCID: PMC3109058.
    Citations: 16     Fields:    Translation:AnimalsCells
  91. Murakami Y, Miller JW, Vavvas DG. RIP kinase-mediated necrosis as an alternative mechanisms of photoreceptor death. Oncotarget. 2011 Jun; 2(6):497-509. PMID: 21670490; PMCID: PMC3248194.
    Citations: 13     Fields:    Translation:HumansAnimalsCells
  92. Giani A, Esmaili DD, Luiselli C, Cigada M, Salvetti P, Miller JW, Staurenghi G. Displayed reflectivity of choroidal neovascular membranes by optical coherence tomography correlates with presence of leakage by fluorescein angiography. Retina. 2011 May; 31(5):942-8. PMID: 21358457.
    Citations: 5     Fields:    Translation:Humans
  93. Salehi-Had H, Roh MI, Giani A, Hisatomi T, Nakao S, Kim IK, Gragoudas ES, Vavvas D, Guccione S, Miller JW. Utilizing targeted gene therapy with nanoparticles binding alpha v beta 3 for imaging and treating choroidal neovascularization. PLoS One. 2011 Apr 29; 6(4):e18864. PMID: 21559527; PMCID: PMC3084713.
    Citations: 7     Fields:    Translation:AnimalsCells
  94. Nakazawa T, Kayama M, Ryu M, Kunikata H, Watanabe R, Yasuda M, Kinugawa J, Vavvas D, Miller JW. Tumor necrosis factor-alpha mediates photoreceptor death in a rodent model of retinal detachment. Invest Ophthalmol Vis Sci. 2011 Mar; 52(3):1384-91. PMID: 21402953; PMCID: PMC3101673.
    Citations: 26     Fields:    Translation:AnimalsCells
  95. Kayama M, Nakazawa T, Thanos A, Morizane Y, Murakami Y, Theodoropoulou S, Abe T, Vavvas D, Miller JW. Heat shock protein 70 (HSP70) is critical for the photoreceptor stress response after retinal detachment via modulating anti-apoptotic Akt kinase. Am J Pathol. 2011 Mar; 178(3):1080-91. PMID: 21356360; PMCID: PMC3069883.
    Citations: 15     Fields:    Translation:AnimalsCells
  96. Rao RC, Chen DF, Miller JW. An epigenetic approach toward understanding ocular a-herpesvirus pathogenesis and treatment. Int Ophthalmol Clin. 2011; 51(4):117-33. PMID: 21897145.
    Citations: 2     Fields:    Translation:HumansCells
  97. Miller JW. Treatment of age-related macular degeneration: beyond VEGF. Jpn J Ophthalmol. 2010 Nov; 54(6):523-8. PMID: 21191711.
    Citations: 10     Fields:    Translation:Humans
  98. Trichonas G, Murakami Y, Thanos A, Morizane Y, Kayama M, Debouck CM, Hisatomi T, Miller JW, Vavvas DG. Receptor interacting protein kinases mediate retinal detachment-induced photoreceptor necrosis and compensate for inhibition of apoptosis. Proc Natl Acad Sci U S A. 2010 Dec 14; 107(50):21695-700. PMID: 21098270; PMCID: PMC3003048.
    Citations: 108     Fields:    Translation:AnimalsCells
  99. Giani A, Cigada M, Choudhry N, Deiro AP, Oldani M, Pellegrini M, Invernizzi A, Duca P, Miller JW, Staurenghi G. Reproducibility of retinal thickness measurements on normal and pathologic eyes by different optical coherence tomography instruments. Am J Ophthalmol. 2010 Dec; 150(6):815-24. PMID: 20965494.
    Citations: 44     Fields:    Translation:Humans
  100. Choudhry N, Giani A, Miller JW. Fundus autofluorescence in geographic atrophy: a review. Semin Ophthalmol. 2010 Sep-Nov; 25(5-6):206-13. PMID: 21091001.
    Citations: 6     Fields:    Translation:Humans
  101. Chen W, Stambolian D, Edwards AO, Branham KE, Othman M, Jakobsdottir J, Tosakulwong N, Pericak-Vance MA, Campochiaro PA, Klein ML, Tan PL, Conley YP, Kanda A, Kopplin L, Li Y, Augustaitis KJ, Karoukis AJ, Scott WK, Agarwal A, Kovach JL, Schwartz SG, Postel EA, Brooks M, Baratz KH, Brown WL, Brucker AJ, Orlin A, Brown G, Ho A, Regillo C, Donoso L, Tian L, Kaderli B, Hadley D, Hagstrom SA, Peachey NS, Klein R, Klein BE, Gotoh N, Yamashiro K, Ferris Iii F, Fagerness JA, Reynolds R, Farrer LA, Kim IK, Miller JW, Cortón M, Carracedo A, Sanchez-Salorio M, Pugh EW, Doheny KF, Brion M, Deangelis MM, Weeks DE, Zack DJ, Chew EY, Heckenlively JR, Yoshimura N, Iyengar SK, Francis PJ, Katsanis N, Seddon JM, Haines JL, Gorin MB, Abecasis GR, Swaroop A. Genetic variants near TIMP3 and high-density lipoprotein-associated loci influence susceptibility to age-related macular degeneration. Proc Natl Acad Sci U S A. 2010 Apr 20; 107(16):7401-6. PMID: 20385819.
    Citations: 217     Fields:    Translation:Humans
  102. Theodoropoulou S, Kolovou PE, Morizane Y, Kayama M, Nicolaou F, Miller JW, Gragoudas E, Ksander BR, Vavvas DG. Retinoblastoma cells are inhibited by aminoimidazole carboxamide ribonucleotide (AICAR) partially through activation of AMP-dependent kinase. FASEB J. 2010 Aug; 24(8):2620-30. PMID: 20371623; PMCID: PMC2909289.
    Citations: 15     Fields:    Translation:HumansCells
  103. Miller JW, Turalba AV. Significant advances in cataract and refractive surgery over the last decade. Preface. Int Ophthalmol Clin. 2010; 50(1):xv. PMID: 20057290.
    Citations:    Fields:    Translation:Humans
  104. Miller JW. Legacy of the age-related eye disease [corrected] study. Arch Ophthalmol. 2009 Dec; 127(12):1680-5. PMID: 20008728.
    Citations: 1     Fields:    Translation:Humans
  105. Trichonas G, Manola A, Morizane Y, Thanos A, Koufomichali X, Papakostas TD, Montezuma S, Young L, Miller JW, Gragoudas E, Vavvas D. A novel nonradioactive method to evaluate vascular barrier breakdown and leakage. Invest Ophthalmol Vis Sci. 2010 Mar; 51(3):1677-82. PMID: 19875655.
    Citations: 8     Fields:    Translation:AnimalsCells
  106. Andreoli MT, Morrison MA, Kim BJ, Chen L, Adams SM, Miller JW, DeAngelis MM, Kim IK. Comprehensive analysis of complement factor H and LOC387715/ARMS2/HTRA1 variants with respect to phenotype in advanced age-related macular degeneration. Am J Ophthalmol. 2009 Dec; 148(6):869-74. PMID: 19796758; PMCID: PMC2787659.
    Citations: 17     Fields:    Translation:HumansCells
  107. Silveira AC, Morrison MA, Ji F, Xu H, Reinecke JB, Adams SM, Arneberg TM, Janssian M, Lee JE, Yuan Y, Schaumberg DA, Kotoula MG, Tsironi EE, Tsiloulis AN, Chatzoulis DZ, Miller JW, Kim IK, Hageman GS, Farrer LA, Haider NB, DeAngelis MM. Convergence of linkage, gene expression and association data demonstrates the influence of the RAR-related orphan receptor alpha (RORA) gene on neovascular AMD: a systems biology based approach. Vision Res. 2010 Mar 31; 50(7):698-715. PMID: 19786043; PMCID: PMC2884392.
    Citations: 25     Fields:    Translation:Humans
  108. Iliaki E, Poulaki V, Mitsiades N, Mitsiades CS, Miller JW, Gragoudas ES. Role of alpha 4 integrin (CD49d) in the pathogenesis of diabetic retinopathy. Invest Ophthalmol Vis Sci. 2009 Oct; 50(10):4898-904. PMID: 19553613.
    Citations: 18     Fields:    Translation:AnimalsCells
  109. Adamis AP, Miller JW. Judah Folkman. Semin Ophthalmol. 2009 May-Jun; 24(3):128-9. PMID: 19437346.
    Citations:    Fields:    Translation:Humans
  110. Turalba AV, Miller JW. Introduction. Semin Ophthalmol. 2009 May-Jun; 24(3):127. PMID: 19437345.
    Citations:    Fields:    Translation:Humans
  111. Poulaki V, Mitsiades CS, Kotoula V, Negri J, McMullan C, Miller JW, Marks PA, Mitsiades N. Molecular sequelae of histone deacetylase inhibition in human retinoblastoma cell lines: clinical implications. Invest Ophthalmol Vis Sci. 2009 Sep; 50(9):4072-9. PMID: 19387079.
    Citations: 4     Fields:    Translation:HumansCells
  112. Hisatomi T, Ishibashi T, Miller JW, Kroemer G. Pharmacological inhibition of mitochondrial membrane permeabilization for neuroprotection. Exp Neurol. 2009 Aug; 218(2):347-52. PMID: 19303007.
    Citations: 6     Fields:    Translation:HumansAnimalsCells
  113. Montezuma SR, Vavvas D, Miller JW. Review of the ocular angiogenesis animal models. Semin Ophthalmol. 2009 Mar-Apr; 24(2):52-61. PMID: 19373687.
    Citations: 15     Fields:    Translation:Animals
  114. Leiderman YI, Miller JW. Proliferative vitreoretinopathy: pathobiology and therapeutic targets. Semin Ophthalmol. 2009 Mar-Apr; 24(2):62-9. PMID: 19373688.
    Citations: 11     Fields:    Translation:HumansAnimals
  115. Jardeleza MS, Miller JW. Review of anti-VEGF therapy in proliferative diabetic retinopathy. Semin Ophthalmol. 2009 Mar-Apr; 24(2):87-92. PMID: 19373692.
    Citations: 31     Fields:    Translation:Humans
  116. Turalba AV, Miller JW. Seminars in Ophthalmology. Introduction. Semin Ophthalmol. 2009 Mar-Apr; 24(2):49. PMID: 19373685.
    Citations:    Fields:    Translation:Humans
  117. Miller JW, Wee R. Ocular pathology. Preface. Int Ophthalmol Clin. 2009; 49(1):xv. PMID: 19125058.
    Citations:    Fields:    Translation:Humans
  118. Kim IK, Ji F, Morrison MA, Adams S, Zhang Q, Lane AM, Capone A, Dryja TP, Ott J, Miller JW, DeAngelis MM. Comprehensive analysis of CRP, CFH Y402H and environmental risk factors on risk of neovascular age-related macular degeneration. Mol Vis. 2008 Aug 11; 14:1487-95. PMID: 18704199; PMCID: PMC2515825.
    Citations: 13     Fields:    Translation:HumansCells
  119. Jager RD, Mieler WF, Miller JW. Age-related macular degeneration. N Engl J Med. 2008 Jun 12; 358(24):2606-17. PMID: 18550876.
    Citations: 359     Fields:    Translation:Humans
  120. Zhang H, Morrison MA, Dewan A, Adams S, Andreoli M, Huynh N, Regan M, Brown A, Miller JW, Kim IK, Hoh J, Deangelis MM. The NEI/NCBI dbGAP database: genotypes and haplotypes that may specifically predispose to risk of neovascular age-related macular degeneration. BMC Med Genet. 2008 Jun 09; 9:51. PMID: 18541031; PMCID: PMC2441616.
    Citations: 32     Fields:    Translation:Humans
  121. Hisatomi T, Nakazawa T, Noda K, Almulki L, Miyahara S, Nakao S, Ito Y, She H, Kohno R, Michaud N, Ishibashi T, Hafezi-Moghadam A, Badley AD, Kroemer G, Miller JW. HIV protease inhibitors provide neuroprotection through inhibition of mitochondrial apoptosis in mice. J Clin Invest. 2008 Jun; 118(6):2025-38. PMID: 18497877; PMCID: PMC2391064.
    Citations: 25     Fields:    Translation:HumansAnimalsCells
  122. Noda K, She H, Nakazawa T, Hisatomi T, Nakao S, Almulki L, Zandi S, Miyahara S, Ito Y, Thomas KL, Garland RC, Miller JW, Gragoudas ES, Mashima Y, Hafezi-Moghadam A. Vascular adhesion protein-1 blockade suppresses choroidal neovascularization. FASEB J. 2008 Aug; 22(8):2928-35. PMID: 18436961; PMCID: PMC2493453.
    Citations: 27     Fields:    Translation:HumansAnimalsCells
  123. She H, Nakazawa T, Matsubara A, Connolly E, Hisatomi T, Noda K, Kim I, Gragoudas ES, Miller JW. Photoreceptor protection after photodynamic therapy using dexamethasone in a rat model of choroidal neovascularization. Invest Ophthalmol Vis Sci. 2008 Nov; 49(11):5008-14. PMID: 18421085.
    Citations: 7     Fields:    Translation:AnimalsCells
  124. Yu HG, Liu X, Kiss S, Connolly E, Gragoudas ES, Michaud NA, Bulgakov OV, Adamian M, DeAngelis MM, Miller JW, Li T, Kim IK. Increased choroidal neovascularization following laser induction in mice lacking lysyl oxidase-like 1. Invest Ophthalmol Vis Sci. 2008 Jun; 49(6):2599-605. PMID: 18296663; PMCID: PMC2770799.
    Citations: 18     Fields:    Translation:Animals
  125. Fan BJ, Pasquale L, Grosskreutz CL, Rhee D, Chen T, DeAngelis MM, Kim I, del Bono E, Miller JW, Li T, Haines JL, Wiggs JL. DNA sequence variants in the LOXL1 gene are associated with pseudoexfoliation glaucoma in a U.S. clinic-based population with broad ethnic diversity. BMC Med Genet. 2008 Feb 06; 9:5. PMID: 18254956; PMCID: PMC2270804.
    Citations: 53     Fields:    Translation:HumansCells
  126. Skondra D, Noda K, Almulki L, Tayyari F, Frimmel S, Nakazawa T, Kim IK, Zandi S, Thomas KL, Miller JW, Gragoudas ES, Hafezi-Moghadam A. Characterization of azurocidin as a permeability factor in the retina: involvement in VEGF-induced and early diabetic blood-retinal barrier breakdown. Invest Ophthalmol Vis Sci. 2008 Feb; 49(2):726-31. PMID: 18235021.
    Citations: 13     Fields:    Translation:Animals
  127. Miyahara S, Almulki L, Noda K, Nakazawa T, Hisatomi T, Nakao S, Thomas KL, Schering A, Zandi S, Frimmel S, Tayyari F, Garland RC, Miller JW, Gragoudas ES, Masli S, Hafezi-Moghadam A. In vivo imaging of endothelial injury in choriocapillaris during endotoxin-induced uveitis. FASEB J. 2008 Jun; 22(6):1973-80. PMID: 18216288.
    Citations: 8     Fields:    Translation:Animals
  128. Kloek CE, Miller JW. Pediatric ophthalmology. Preface. Int Ophthalmol Clin. 2008; 48(2):xvii. PMID: 18427254.
    Citations:    Fields:    Translation:Humans
  129. Miller JW. Higher irradiance and photodynamic therapy for age-related macular degeneration (an AOS thesis). Trans Am Ophthalmol Soc. 2008; 106:357-82. PMID: 19277246; PMCID: PMC2646424.
    Citations: 3     Fields:    Translation:AnimalsCells
  130. Deangelis MM, Ji F, Adams S, Morrison MA, Harring AJ, Sweeney MO, Capone A, Miller JW, Dryja TP, Ott J, Kim IK. Alleles in the HtrA serine peptidase 1 gene alter the risk of neovascular age-related macular degeneration. Ophthalmology. 2008 Jul; 115(7):1209-1215.e7. PMID: 18164066; PMCID: PMC4242506.
    Citations: 37     Fields:    Translation:HumansCells
  131. Noda K, Miyahara S, Nakazawa T, Almulki L, Nakao S, Hisatomi T, She H, Thomas KL, Garland RC, Miller JW, Gragoudas ES, Kawai Y, Mashima Y, Hafezi-Moghadam A. Inhibition of vascular adhesion protein-1 suppresses endotoxin-induced uveitis. FASEB J. 2008 Apr; 22(4):1094-103. PMID: 18032635.
    Citations: 16     Fields:    Translation:HumansAnimalsCells
  132. Andreoli CM, Miller JW. Anti-vascular endothelial growth factor therapy for ocular neovascular disease. Curr Opin Ophthalmol. 2007 Nov; 18(6):502-8. PMID: 18163003.
    Citations: 70     Fields:    Translation:Humans
  133. Matsubara A, Nakazawa T, Noda K, She H, Connolly E, Young TA, Ogura Y, Gragoudas ES, Miller JW. Photodynamic therapy induces caspase-dependent apoptosis in rat CNV model. Invest Ophthalmol Vis Sci. 2007 Oct; 48(10):4741-7. PMID: 17898299.
    Citations: 4     Fields:    Translation:AnimalsCells
  134. Poulaki V, Mitsiades CS, Kotoula V, Negri J, McMillin D, Miller JW, Mitsiades N. The proteasome inhibitor bortezomib induces apoptosis in human retinoblastoma cell lines in vitro. Invest Ophthalmol Vis Sci. 2007 Oct; 48(10):4706-19. PMID: 17898295.
    Citations: 13     Fields:    Translation:HumansCells
  135. Nakazawa T, Takeda M, Lewis GP, Cho KS, Jiao J, Wilhelmsson U, Fisher SK, Pekny M, Chen DF, Miller JW. Attenuated glial reactions and photoreceptor degeneration after retinal detachment in mice deficient in glial fibrillary acidic protein and vimentin. Invest Ophthalmol Vis Sci. 2007 Jun; 48(6):2760-8. PMID: 17525210; PMCID: PMC2613948.
    Citations: 54     Fields:    Translation:AnimalsCells
  136. Marneros AG, She H, Zambarakji H, Hashizume H, Connolly EJ, Kim I, Gragoudas ES, Miller JW, Olsen BR. Endogenous endostatin inhibits choroidal neovascularization. FASEB J. 2007 Dec; 21(14):3809-18. PMID: 17526870.
    Citations: 18     Fields:    Translation:HumansAnimals
  137. She H, Nakazawa T, Matsubara A, Hisatomi T, Young TA, Michaud N, Connolly E, Hafezi-Moghadam A, Gragoudas ES, Miller JW. Reduced photoreceptor damage after photodynamic therapy through blockade of nitric oxide synthase in a model of choroidal neovascularization. Invest Ophthalmol Vis Sci. 2007 May; 48(5):2268-77. PMID: 17460290.
    Citations: 13     Fields:    Translation:AnimalsCells
  138. Poulaki V, Iliaki E, Mitsiades N, Mitsiades CS, Paulus YN, Bula DV, Gragoudas ES, Miller JW. Inhibition of Hsp90 attenuates inflammation in endotoxin-induced uveitis. FASEB J. 2007 Jul; 21(9):2113-23. PMID: 17400913.
    Citations: 27     Fields:    Translation:AnimalsCells
  139. Nakazawa T, Hisatomi T, Nakazawa C, Noda K, Maruyama K, She H, Matsubara A, Miyahara S, Nakao S, Yin Y, Benowitz L, Hafezi-Moghadam A, Miller JW. Monocyte chemoattractant protein 1 mediates retinal detachment-induced photoreceptor apoptosis. Proc Natl Acad Sci U S A. 2007 Feb 13; 104(7):2425-30. PMID: 17284607; PMCID: PMC1892947.
    Citations: 103     Fields:    Translation:HumansCells
  140. Hafezi-Moghadam A, Noda K, Almulki L, Iliaki EF, Poulaki V, Thomas KL, Nakazawa T, Hisatomi T, Miller JW, Gragoudas ES. VLA-4 blockade suppresses endotoxin-induced uveitis: in vivo evidence for functional integrin up-regulation. FASEB J. 2007 Feb; 21(2):464-74. PMID: 17202250.
    Citations: 14     Fields:    Translation:AnimalsCells
  141. Kalayoglu MV, Miller JW. Infection, inflammation and age-related macular degeneration. Clin Exp Ophthalmol. 2007 Jan-Feb; 35(1):3-4. PMID: 17300563.
    Citations: 2     Fields:    Translation:HumansCells
  142. Barouch FC, Miller JW. The role of inflammation and infection in age-related macular degeneration. Int Ophthalmol Clin. 2007; 47(2):185-97. PMID: 17450018.
    Citations: 7     Fields:    Translation:Humans
  143. DeAngelis MM, Ji F, Kim IK, Adams S, Capone A, Ott J, Miller JW, Dryja TP. Cigarette smoking, CFH, APOE, ELOVL4, and risk of neovascular age-related macular degeneration. Arch Ophthalmol. 2007 Jan; 125(1):49-54. PMID: 17210851.
    Citations: 40     Fields:    Translation:Humans
  144. Pachydaki S, Sobrin L, Miller JW. Photodynamic therapy and combination treatments. Int Ophthalmol Clin. 2007; 47(1):95-115. PMID: 17237676.
    Citations: 1     Fields:    Translation:HumansAnimals
  145. Miller JW, Andreoli CM. Preface. Int Ophthalmol Clin. 2007; 47(2):xv. PMID: 29664437.
    Citations:    Fields:    
  146. Nakazawa T, Nakazawa C, Matsubara A, Noda K, Hisatomi T, She H, Michaud N, Hafezi-Moghadam A, Miller JW, Benowitz LI. Tumor necrosis factor-alpha mediates oligodendrocyte death and delayed retinal ganglion cell loss in a mouse model of glaucoma. J Neurosci. 2006 Dec 06; 26(49):12633-41. PMID: 17151265.
    Citations: 125     Fields:    Translation:AnimalsCells
  147. Sobrin L, Miller JW. Optical coherence tomography pseudo-macular hole appearance after photodynamic therapy. Br J Ophthalmol. 2006 Nov; 90(11):1434-5. PMID: 17057177; PMCID: PMC1857485.
    Citations:    Fields:    Translation:Humans
  148. Miller JW. Introducing Evangelos S. Gragoudas, the 2006 recipient of the Weisenfeld Award. Invest Ophthalmol Vis Sci. 2006 Nov; 47(11):4665. PMID: 17065471.
    Citations: 2     Fields:    Translation:Humans
  149. Hisatomi T, Sonoda KH, Ishikawa F, Qiao H, Nakazawa T, Fukata M, Nakamura T, Noda K, Miyahara S, Harada M, Kinoshita S, Hafezi-Moghadam A, Ishibashi T, Miller JW. Identification of resident and inflammatory bone marrow derived cells in the sclera by bone marrow and haematopoietic stem cell transplantation. Br J Ophthalmol. 2007 Apr; 91(4):520-6. PMID: 17035278; PMCID: PMC1994730.
    Citations: 3     Fields:    Translation:AnimalsCells
  150. Barouch FC, Miller JW. Potential future targets for treating ocular neovascularization. Ophthalmol Clin North Am. 2006 Sep; 19(3):401-9. PMID: 16935215.
    Citations: 1     Fields:    Translation:HumansAnimals
  151. Zambarakji HJ, Lane AM, Ezra E, Gauthier D, Goitein M, Adams JA, Munzenrider JE, Miller JW, Gragoudas ES. Proton beam irradiation for neovascular age-related macular degeneration. Ophthalmology. 2006 Nov; 113(11):2012-9. PMID: 16935343.
    Citations: 9     Fields:    Translation:Humans
  152. Nakazawa T, Matsubara A, Noda K, Hisatomi T, She H, Skondra D, Miyahara S, Sobrin L, Thomas KL, Chen DF, Grosskreutz CL, Hafezi-Moghadam A, Miller JW. Characterization of cytokine responses to retinal detachment in rats. Mol Vis. 2006 Aug 07; 12:867-78. PMID: 16917487.
    Citations: 48     Fields:    Translation:AnimalsCells
  153. Ament CS, Zacks DN, Lane AM, Krzystolik M, D'Amico DJ, Mukai S, Young LH, Loewenstein J, Arroyo J, Miller JW. Predictors of visual outcome and choroidal neovascular membrane formation after traumatic choroidal rupture. Arch Ophthalmol. 2006 Jul; 124(7):957-66. PMID: 16832018.
    Citations: 11     Fields:    Translation:Humans
  154. Miller JW. Using a drug before the risks and benefits are known from a phase 3 clinical trial: thoughts on compassion. Arch Ophthalmol. 2006 Jul; 124(7):1029-31. PMID: 16832027.
    Citations: 1     Fields:    Translation:Humans
  155. Matsubara A, Nakazawa T, Husain D, Iliaki E, Connolly E, Michaud NA, Gragoudas ES, Miller JW. Investigating the effect of ciliary body photodynamic therapy in a glaucoma mouse model. Invest Ophthalmol Vis Sci. 2006 Jun; 47(6):2498-507. PMID: 16723462.
    Citations: 9     Fields:    Translation:AnimalsCells
  156. Chen TC, Cense B, Miller JW, Rubin PA, Deschler DG, Gragoudas ES, de Boer JF. Histologic correlation of in vivo optical coherence tomography images of the human retina. Am J Ophthalmol. 2006 Jun; 141(6):1165-8. PMID: 16765704.
    Citations: 33     Fields:    Translation:Humans
  157. Zambarakji HJ, Nakazawa T, Connolly E, Lane AM, Mallemadugula S, Kaplan M, Michaud N, Hafezi-Moghadam A, Gragoudas ES, Miller JW. Dose-dependent effect of pitavastatin on VEGF and angiogenesis in a mouse model of choroidal neovascularization. Invest Ophthalmol Vis Sci. 2006 Jun; 47(6):2623-31. PMID: 16723479.
    Citations: 4     Fields:    Translation:Animals
  158. Filippopoulos T, Matsubara A, Danias J, Huang W, Dobberfuhl A, Ren L, Mittag T, Miller JW, Grosskreutz CL. Predictability and limitations of non-invasive murine tonometry: comparison of two devices. Exp Eye Res. 2006 Jul; 83(1):194-201. PMID: 16564045.
    Citations: 14     Fields:    Translation:Animals
  159. Kim IK, Husain D, Michaud N, Connolly E, Lane AM, Durrani K, Hafezi-Moghadam A, Gragoudas ES, O'Neill CA, Beyer JC, Miller JW. Effect of intravitreal injection of ranibizumab in combination with verteporfin PDT on normal primate retina and choroid. Invest Ophthalmol Vis Sci. 2006 Jan; 47(1):357-63. PMID: 16384985.
    Citations: 11     Fields:    Translation:Animals
  160. Bressler NM, Bressler SB, Haynes LA, Hao Y, Kaiser PK, Miller JW, Naor J, Potter MJ, Pournaras CJ, Reaves A, Rosenfeld PJ, Schmidt-Erfurth U, Slakter JS, Strong A, Vannier S. Verteporfin therapy for subfoveal choroidal neovascularization in age-related macular degeneration: four-year results of an open-label extension of 2 randomized clinical trials: TAP Report No. 7. Arch Ophthalmol. 2005 Sep; 123(9):1283-5. PMID: 16157822.
    Citations: 9     Fields:    Translation:HumansCTClinical Trials
  161. Durand ML, Kim IK, D'Amico DJ, Loewenstein JI, Tobin EH, Kieval SJ, Martin SS, Azar DT, Miller FS, Lujan BJ, Miller JW. Successful treatment of Fusarium endophthalmitis with voriconazole and Aspergillus endophthalmitis with voriconazole plus caspofungin. Am J Ophthalmol. 2005 Sep; 140(3):552-4. PMID: 16139017.
    Citations: 22     Fields:    Translation:HumansAnimals
  162. Rosenfeld PJ, Schwartz SD, Blumenkranz MS, Miller JW, Haller JA, Reimann JD, Greene WL, Shams N. Maximum tolerated dose of a humanized anti-vascular endothelial growth factor antibody fragment for treating neovascular age-related macular degeneration. Ophthalmology. 2005 Jun; 112(6):1048-53. PMID: 15885778.
    Citations: 44     Fields:    Translation:HumansCTClinical Trials
  163. Kalayoglu MV, Bula D, Arroyo J, Gragoudas ES, D'Amico D, Miller JW. Identification of Chlamydia pneumoniae within human choroidal neovascular membranes secondary to age-related macular degeneration. Graefes Arch Clin Exp Ophthalmol. 2005 Nov; 243(11):1080-90. PMID: 15909160.
    Citations: 27     Fields:    Translation:HumansCells
  164. Husain D, Kim I, Gauthier D, Lane AM, Tsilimbaris MK, Ezra E, Connolly EJ, Michaud N, Gragoudas ES, O'Neill CA, Beyer JC, Miller JW. Safety and efficacy of intravitreal injection of ranibizumab in combination with verteporfin PDT on experimental choroidal neovascularization in the monkey. Arch Ophthalmol. 2005 Apr; 123(4):509-16. PMID: 15824225.
    Citations: 22     Fields:    Translation:Animals
  165. Bhisitkul RB, Robinson GS, Moulton RS, Claffey KP, Gragoudas ES, Miller JW. An antisense oligodeoxynucleotide against vascular endothelial growth factor in a nonhuman primate model of iris neovascularization. Arch Ophthalmol. 2005 Feb; 123(2):214-9. PMID: 15710818.
    Citations: 5     Fields:    Translation:Animals
  166. Sun JK, Miller JW. Medical treatment of choroidal neovascularization secondary to age-related macular degeneration. Int Ophthalmol Clin. 2005; 45(4):115-32. PMID: 16199971.
    Citations:    Fields:    Translation:Humans
  167. Poulaki V, Mitsiades CS, McMullan C, Fanourakis G, Negri J, Goudopoulou A, Halikias IX, Voutsinas G, Tseleni-Balafouta S, Miller JW, Mitsiades N. Human retinoblastoma cells are resistant to apoptosis induced by death receptors: role of caspase-8 gene silencing. Invest Ophthalmol Vis Sci. 2005 Jan; 46(1):358-66. PMID: 15623796.
    Citations: 7     Fields:    Translation:HumansCells
  168. Zacks DN, Zheng QD, Han Y, Bakhru R, Miller JW. FAS-mediated apoptosis and its relation to intrinsic pathway activation in an experimental model of retinal detachment. Invest Ophthalmol Vis Sci. 2004 Dec; 45(12):4563-9. PMID: 15557468.
    Citations: 37     Fields:    Translation:Animals
  169. Bandello F, Blinder K, Bressler NM, Brown AL, Miller JW, Potter MJ, Pournaras C, Reaves A, Rosenfeld PJ, Slakter JS, Soubrane G, Strong HA, Stur M. Verteporfin in Photodynamic Therapy: report no. 5. Ophthalmology. 2004 Nov; 111(11):2144. PMID: 15522385.
    Citations: 1     Fields:    Translation:Humans
  170. Renno RZ, Terada Y, Haddadin MJ, Michaud NA, Gragoudas ES, Miller JW. Selective photodynamic therapy by targeted verteporfin delivery to experimental choroidal neovascularization mediated by a homing peptide to vascular endothelial growth factor receptor-2. Arch Ophthalmol. 2004 Jul; 122(7):1002-11. PMID: 15249365.
    Citations: 15     Fields:    Translation:Animals
  171. Yeh DC, Bula DV, Miller JW, Gragoudas ES, Arroyo JG. Expression of leukocyte adhesion molecules in human subfoveal choroidal neovascular membranes treated with and without photodynamic therapy. Invest Ophthalmol Vis Sci. 2004 Jul; 45(7):2368-73. PMID: 15223819.
    Citations: 13     Fields:    Translation:Humans
  172. DeAngelis MM, Lane AM, Shah CP, Ott J, Dryja TP, Miller JW. Extremely discordant sib-pair study design to determine risk factors for neovascular age-related macular degeneration. Arch Ophthalmol. 2004 Apr; 122(4):575-80. PMID: 15078676.
    Citations: 15     Fields:    Translation:Humans
  173. Arnold JJ, Blinder KJ, Bressler NM, Bressler SB, Burdan A, Haynes L, Lim JI, Miller JW, Potter MJ, Reaves A, Rosenfeld PJ, Sickenberg M, Slakter JS, Soubrane G, Strong HA, Stur M. Acute severe visual acuity decrease after photodynamic therapy with verteporfin: case reports from randomized clinical trials-TAP and VIP report no. 3. Am J Ophthalmol. 2004 Apr; 137(4):683-96. PMID: 15059708.
    Citations: 20     Fields:    Translation:Humans
  174. Azab M, Benchaboune M, Blinder KJ, Bressler NM, Bressler SB, Gragoudas ES, Fish GE, Hao Y, Haynes L, Lim JI, Menchini U, Miller JW, Mones J, Potter MJ, Reaves A, Rosenfeld PJ, Strong A, Su XY, Slakter JS, Schmidt-Erfurth U, Sorenson JA. Verteporfin therapy of subfoveal choroidal neovascularization in age-related macular degeneration: meta-analysis of 2-year safety results in three randomized clinical trials: Treatment Of Age-Related Macular Degeneration With Photodynamic Therapy and Verteporfin In Photodynamic Therapy Study Report no. 4. Retina. 2004 Feb; 24(1):1-12. PMID: 15076937.
    Citations: 12     Fields:    Translation:Humans
  175. Kalayoglu MV, Pavan-Langston D, Miller JW. Treatment of chlamydial eye infections. Int Ophthalmol Clin. 2004; 44(3):135-46. PMID: 15211182.
    Citations: 1     Fields:    Translation:Humans
  176. Barouch FC, Miller JW. Anti-vascular endothelial growth factor strategies for the treatment of choroidal neovascularization from age-related macular degeneration. Int Ophthalmol Clin. 2004; 44(3):23-32. PMID: 15211174.
    Citations: 9     Fields:    Translation:HumansAnimals
  177. Waheed NK, Miller JW. Aptamers, intramers, and vascular endothelial growth factor. Int Ophthalmol Clin. 2004; 44(3):11-22. PMID: 15211173.
    Citations: 3     Fields:    Translation:HumansAnimals
  178. Ufret-Vincenty RL, Miller JW, Gragoudas ES. Photosensitizers in photodynamic therapy of choroidal neovascularization. Int Ophthalmol Clin. 2004; 44(3):63-80. PMID: 15211178.
    Citations:    Fields:    Translation:Humans