Contact, publication, and social network information about Harvard faculty and fellows. Harvard Catalyst Profiles
Last Name

profileDmitry Gerashchenko, Ph.D.

TitleAssistant Professor of Psychiatry
InstitutionVeterans Affairs Boston Healthcare System
AddressBoston Va Med Ctr-W Roxbury
2 A -107
1400 VFW Pkwy
West Roxbury MA 02132
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Collapse Research 
Collapse research activities and funding
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
R43OD023231     (GERASHCHENKO, LUDMILA)Aug 12, 2017 - Aug 11, 2018
System for providing an interface for interacting with an animal
Role: Principal Investigator

R43AG056250     (GARTENBERG, DANIEL)May 1, 2017 - Apr 30, 2019
Non-pharmacological improvement of sleep structure in older people
Role: Co-Principal Investigator

R21NS092926     (GERASHCHENKO, DMITRY)Sep 1, 2015 - Aug 31, 2017
Role of nNOS cortical neurons in slow wave activity production and cognition
Role: Principal Investigator

R43NS077514     (GERASHCHENKO, LUDMILA)Apr 1, 2012 - Mar 31, 2014
AAV-based toolkit for targeting specific cell types
Role: Principal Investigator

R01NS064193     (GERASHCHENKO, DMITRY)May 1, 2010 - Apr 30, 2014
Role of cortical interneurons in synchronization of brain electroencephalogram
Role: Principal Investigator

Collapse Bibliographic 
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Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Zielinski MR, Gerashchenko D. Sleep-inducing effect of substance P-cholera toxin A subunit in mice. Neurosci Lett. 2017 10 17; 659:44-47. PMID: 28866052.
    View in: PubMed
  2. Gerashchenko D, Pasumarthi RK, Kilduff TS. Plasticity-Related Gene Expression During Eszopiclone-Induced Sleep. Sleep. 2017 Jul 01; 40(7). PMID: 28605546.
    View in: PubMed
  3. Zielinski MR, Gerashchenko D, Karpova SA, Konanki V, McCarley RW, Sutterwala FS, Strecker RE, Basheer R. The NLRP3 inflammasome modulates sleep and NREM sleep delta power induced by spontaneous wakefulness, sleep deprivation and lipopolysaccharide. Brain Behav Immun. 2017 May; 62:137-150. PMID: 28109896.
    View in: PubMed
  4. Zielinski MR, Kim Y, Karpova SA, McCarley RW, Strecker RE, Gerashchenko D. Chronic sleep restriction elevates brain interleukin-1 beta and tumor necrosis factor-alpha and attenuates brain-derived neurotrophic factor expression. Neurosci Lett. 2014 Sep 19; 580:27-31. PMID: 25093703; PMCID: PMC4162816.
  5. Morairty SR, Dittrich L, Pasumarthi RK, Valladao D, Heiss JE, Gerashchenko D, Kilduff TS. A role for cortical nNOS/NK1 neurons in coupling homeostatic sleep drive to EEG slow wave activity. Proc Natl Acad Sci U S A. 2013 Dec 10; 110(50):20272-7. PMID: 24191004; PMCID: PMC3864296.
  6. Zielinski MR, Gerashchenko L, Karpova SA, Gerashchenko D. A novel telemetric system to measure polysomnographic biopotentials in freely moving animals. J Neurosci Methods. 2013 Jun 15; 216(2):79-86. PMID: 23563323; PMCID: PMC3679249.
  7. Liu M, Blanco-Centurion C, Konadhode R, Begum S, Pelluru D, Gerashchenko D, Sakurai T, Yanagisawa M, van den Pol AN, Shiromani PJ. Orexin gene transfer into zona incerta neurons suppresses muscle paralysis in narcoleptic mice. J Neurosci. 2011 Apr 20; 31(16):6028-40. PMID: 21508228; PMCID: PMC3634582.
  8. Wisor JP, Gerashchenko D, Kilduff TS. Sleep-active neuronal nitric oxide synthase-positive cells of the cerebral cortex: a local regulator of sleep? Curr Top Med Chem. 2011; 11(19):2483-9. PMID: 21906016; PMCID: PMC3899842.
  9. Gerashchenko D, Wisor JP, Kilduff TS. Sleep-active cells in the cerebral cortex and their role in slow-wave activity. Sleep Biol Rhythms. 2011 Jan; 9(s1):71-77. PMID: 21625335.
    View in: PubMed
  10. Gerashchenko D, Horvath TL, Xie XS. Direct inhibition of hypocretin/orexin neurons in the lateral hypothalamus by nociceptin/orphanin FQ blocks stress-induced analgesia in rats. Neuropharmacology. 2011 Mar; 60(4):543-9. PMID: 21195099; PMCID: PMC3031765.
  11. Kilduff TS, Cauli B, Gerashchenko D. Activation of cortical interneurons during sleep: an anatomical link to homeostatic sleep regulation? Trends Neurosci. 2011 Jan; 34(1):10-9. PMID: 21030095; PMCID: PMC3014438.
  12. Thompson CL, Wisor JP, Lee CK, Pathak SD, Gerashchenko D, Smith KA, Fischer SR, Kuan CL, Sunkin SM, Ng LL, Lau C, Hawrylycz M, Jones AR, Kilduff TS, Lein ES. Molecular and anatomical signatures of sleep deprivation in the mouse brain. Front Neurosci. 2010; 4:165. PMID: 21088695; PMCID: PMC2981377.
  13. Hara J, Gerashchenko D, Wisor JP, Sakurai T, Xie X, Kilduff TS. Thyrotropin-releasing hormone increases behavioral arousal through modulation of hypocretin/orexin neurons. J Neurosci. 2009 Mar 25; 29(12):3705-14. PMID: 19321767; PMCID: PMC2712668.
  14. Gerashchenko D, Wisor JP, Burns D, Reh RK, Shiromani PJ, Sakurai T, de la Iglesia HO, Kilduff TS. Identification of a population of sleep-active cerebral cortex neurons. Proc Natl Acad Sci U S A. 2008 Jul 22; 105(29):10227-32. PMID: 18645184; PMCID: PMC2481371.
  15. Wisor JP, Pasumarthi RK, Gerashchenko D, Thompson CL, Pathak S, Sancar A, Franken P, Lein ES, Kilduff TS. Sleep deprivation effects on circadian clock gene expression in the cerebral cortex parallel electroencephalographic differences among mouse strains. J Neurosci. 2008 Jul 09; 28(28):7193-201. PMID: 18614689; PMCID: PMC2603080.
  16. Terao A, Huang ZL, Wisor JP, Mochizuki T, Gerashchenko D, Urade Y, Kilduff TS. Gene expression in the rat brain during prostaglandin D2 and adenosinergically-induced sleep. J Neurochem. 2008 May; 105(4):1480-98. PMID: 18331290; PMCID: PMC2590502.
  17. Blanco-Centurion C, Gerashchenko D, Shiromani PJ. Effects of saporin-induced lesions of three arousal populations on daily levels of sleep and wake. J Neurosci. 2007 Dec 19; 27(51):14041-8. PMID: 18094243; PMCID: PMC2975593.
  18. Blanco-Centurion C, Xu M, Murillo-Rodriguez E, Gerashchenko D, Shiromani AM, Salin-Pascual RJ, Hof PR, Shiromani PJ. Adenosine and sleep homeostasis in the Basal forebrain. J Neurosci. 2006 Aug 02; 26(31):8092-100. PMID: 16885223.
    View in: PubMed
  19. Gerashchenko D, Chou TC, Blanco-Centurion CA, Saper CB, Shiromani PJ. Effects of lesions of the histaminergic tuberomammillary nucleus on spontaneous sleep in rats. Sleep. 2004 Nov 01; 27(7):1275-81. PMID: 15586780; PMCID: PMC1249486.
  20. Gerashchenko D, Shiromani PJ. Effects of inflammation produced by chronic lipopolysaccharide administration on the survival of hypocretin neurons and sleep. Brain Res. 2004 Sep 03; 1019(1-2):162-9. PMID: 15306250.
    View in: PubMed
  21. Desarnaud F, Murillo-Rodriguez E, Lin L, Xu M, Gerashchenko D, Shiromani SN, Nishino S, Mignot E, Shiromani PJ. The diurnal rhythm of hypocretin in young and old F344 rats. Sleep. 2004 Aug 01; 27(5):851-6. PMID: 15453542; PMCID: PMC1201560.
  22. Blanco-Centurion C, Gerashchenko D, Salin-Pascual RJ, Shiromani PJ. Effects of hypocretin2-saporin and antidopamine-beta-hydroxylase-saporin neurotoxic lesions of the dorsolateral pons on sleep and muscle tone. Eur J Neurosci. 2004 May; 19(10):2741-52. PMID: 15147308; PMCID: PMC1201541.
  23. Shiromani PJ, Xu M, Winston EM, Shiromani SN, Gerashchenko D, Weaver DR. Sleep rhythmicity and homeostasis in mice with targeted disruption of mPeriod genes. Am J Physiol Regul Integr Comp Physiol. 2004 Jul; 287(1):R47-57. PMID: 15031135.
    View in: PubMed
  24. Gerashchenko D, Shiromani PJ. Different neuronal phenotypes in the lateral hypothalamus and their role in sleep and wakefulness. Mol Neurobiol. 2004 Feb; 29(1):41-59. PMID: 15034222.
    View in: PubMed
  25. Gerashchenko D, Murillo-Rodriguez E, Lin L, Xu M, Hallett L, Nishino S, Mignot E, Shiromani PJ. Relationship between CSF hypocretin levels and hypocretin neuronal loss. Exp Neurol. 2003 Dec; 184(2):1010-6. PMID: 14769395.
    View in: PubMed
  26. Scammell TE, Gerashchenko DY, Mochizuki T, McCarthy MT, Estabrooke IV, Sears CA, Saper CB, Urade Y, Hayaishi O. An adenosine A2a agonist increases sleep and induces Fos in ventrolateral preoptic neurons. Neuroscience. 2001; 107(4):653-63. PMID: 11720788.
    View in: PubMed
  27. Gerashchenko DY, Beuckmann CT, Marcheselli VL, Gordon WC, Kanaoka Y, Eguchi N, Urade Y, Hayaishi O, Bazan NG. Localization of lipocalin-type prostaglandin D synthase (beta-trace) in iris, ciliary body, and eye fluids. Invest Ophthalmol Vis Sci. 1998 Jan; 39(1):198-203. PMID: 9430563.
    View in: PubMed
  28. Beuckmann CT, Gordon WC, Kanaoka Y, Eguchi N, Marcheselli VL, Gerashchenko DY, Urade Y, Hayaishi O, Bazan NG. Lipocalin-type prostaglandin D synthase (beta-trace) is located in pigment epithelial cells of rat retina and accumulates within interphotoreceptor matrix. J Neurosci. 1996 Oct 01; 16(19):6119-24. PMID: 8815894.
    View in: PubMed
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