Harvard Catalyst Profiles

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Michael J Duggan, D.V.M.


Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Naar L, Dorken Gallastegi A, Dowling M, Mashbari HNA, Wallace B, Bankhead-Kendall B, Beagle J, Pallotta JB, Breen K, Velmahos GC, Duggan MJ, King CDR. Chitosan-based lifefoam improves survival in lethal noncompressible abdominal bleeding in swine. Surgery. 2022 07; 172(1):421-426. PMID: 35184891.
    Citations:    Fields:    Translation:HumansAnimals
  2. Gruionu G, Gruionu LG, Duggan M, Surlin V, Patrascu S, Velmahos G. Feasibility of a Portable Abdominal Insufflation Device for Controlling Intraperitoneal Bleeding After Abdominal Blunt Trauma. Surg Innov. 2019 Dec; 26(6):662-667. PMID: 31418332.
    Citations:    Fields:    Translation:Animals
  3. Sreeram G, Hyatt D, Fischer S, Thourani VH, Duggan M. Atrioventricular Disruption After Aortic Valve Surgery: Early Detection by Intraoperative Echocardiography: A Case Report. A A Pract. 2018 Jun 01; 10(11):302-306. PMID: 29634563.
    Citations:    Fields:    
  4. Vishwanath K, Gurjar R, Wolf D, Riccardi S, Duggan M, King D. Diffuse optical monitoring of peripheral tissues during uncontrolled internal hemorrhage in a porcine model. Biomed Opt Express. 2018 Feb 01; 9(2):569-580. PMID: 29552394; PMCID: PMC5854059.
    Citations: 3     
  5. Nikolian VC, Pan B, Mesar T, Dennahy IS, Georgoff PE, Duan X, Liu B, Wu X, Duggan MJ, Alam HB, Li Y. Lung Protective Effects of Low-Volume Resuscitation and Pharmacologic Treatment of Swine Subjected to Polytrauma and Hemorrhagic Shock. Inflammation. 2017 Aug; 40(4):1264-1274. PMID: 28493077.
    Citations: 1     Fields:    Translation:HumansAnimalsCells
  6. Shi W, McIver BV, Kalra K, Sarin EL, Schmarkey S, Duggan M, Thourani VH, Guyton RA, Padala M. A Swine Model of Percutaneous Intracoronary Ethanol Induced Acute Myocardial Infarction and Ischemic Mitral Regurgitation. J Cardiovasc Transl Res. 2017 Aug; 10(4):391-400. PMID: 28577038.
    Citations: 8     Fields:    Translation:Animals
  7. Avery RK, Albadawi H, Akbari M, Zhang YS, Duggan MJ, Sahani DV, Olsen BD, Khademhosseini A, Oklu R. An injectable shear-thinning biomaterial for endovascular embolization. Sci Transl Med. 2016 11 16; 8(365):365ra156. PMID: 27856795.
    Citations: 42     Fields:    Translation:HumansAnimals
  8. Oto J, Su Z, Duggan M, Wang J, King DR, Kacmarek RM, Jiang Y. Efficacy of coaxial ventilation with a novel endotracheal catheter equipped with a functional cuff: A swine model study. Eur J Anaesthesiol. 2016 Apr; 33(4):250-6. PMID: 26479512.
    Citations: 1     Fields:    Translation:Animals
  9. Rago AP, Duggan MJ, Hannett P, Brennecke LH, LaRochelle A, Khatri C, Zugates GT, Chang Y, Sharma U, King DR. Chronic safety assessment of hemostatic self-expanding foam: 90-day survival study and intramuscular biocompatibility. J Trauma Acute Care Surg. 2015 Oct; 79(4 Suppl 2):S78-84. PMID: 26131784.
    Citations: 1     Fields:    Translation:Animals
  10. Navarro Alvarez N, Zhu A, Arellano RS, Randolph MA, Duggan M, Scott Arn J, Huang CA, Sachs DH, Vagefi PA. Postnatal xenogeneic B-cell tolerance in swine following in utero intraportal antigen exposure. Xenotransplantation. 2015 Sep-Oct; 22(5):368-78. PMID: 26314946.
    Citations:    Fields:    Translation:AnimalsCells
  11. Su Z, Oto J, Wang J, Kimball WR, Chenelle CT, Kacmarek RM, King DR, Jiang Y, Duggan MJ. Validation of Respiratory Inductance Plethysmography for Measuring Tidal Volume in Swine. Comp Med. 2015 Jun; 65(3):225-31. PMID: 26141447; PMCID: PMC4485631.
    Citations:    Fields:    Translation:Animals
  12. Dowling MB, MacIntire IC, White JC, Narayan M, Duggan MJ, King DR, Raghavan SR. Sprayable Foams Based on an Amphiphilic Biopolymer for Control of Hemorrhage Without Compression. ACS Biomater Sci Eng. 2015 Jun 08; 1(6):440-447. PMID: 33445247.
    Citations: 2     Fields:    
  13. Rago AP, Marini J, Duggan MJ, Beagle J, Runyan G, Sharma U, Peev M, King DR. Diagnosis and deployment of a self-expanding foam for abdominal exsanguination: Translational questions for human use. J Trauma Acute Care Surg. 2015 Mar; 78(3):607-13. PMID: 25710434.
    Citations: 3     Fields:    Translation:HumansAnimals
  14. Rago AP, Larentzakis A, Marini J, Picard A, Duggan MJ, Busold R, Helmick M, Zugates G, Beagle J, Sharma U, King DR. Efficacy of a prehospital self-expanding polyurethane foam for noncompressible hemorrhage under extreme operational conditions. J Trauma Acute Care Surg. 2015 Feb; 78(2):324-9. PMID: 25757118.
    Citations: 6     Fields:    Translation:Animals
  15. Rago AP, Duggan MJ, Beagle J, Peev MP, Marini J, Hwabejire JO, Hannett P, Zugates G, Busold R, Helmick M, Velmahos G, Demoya MA, Yeh DD, Fagenholz PJ, Sharma U, King DR. Self-expanding foam for prehospital treatment of intra-abdominal hemorrhage: 28-day survival and safety. J Trauma Acute Care Surg. 2014 Sep; 77(3 Suppl 2):S127-33. PMID: 25159345.
    Citations: 6     Fields:    Translation:AnimalsCells
  16. Rago A, Duggan MJ, Marini J, Beagle J, Velmahos G, De Moya MA, Sharma U, Hwabejire J, King DR. Self-expanding foam improves survival following a lethal, exsanguinating iliac artery injury. J Trauma Acute Care Surg. 2014 Jul; 77(1):73-7. PMID: 24977758.
    Citations: 7     Fields:    Translation:Animals
  17. Dowling MB, Smith W, Balogh P, Duggan MJ, MacIntire IC, Harris E, Mesar T, Raghavan SR, King DR. Hydrophobically-modified chitosan foam: description and hemostatic efficacy. J Surg Res. 2015 Jan; 193(1):316-23. PMID: 25016441.
    Citations: 12     Fields:    Translation:HumansAnimalsCells
  18. Sillesen M, Johansson PI, Rasmussen LS, Jin G, Jepsen CH, Imam A, Hwabejire JO, Deperalta D, Duggan M, DeMoya M, Velmahos GC, Alam HB. Fresh frozen plasma resuscitation attenuates platelet dysfunction compared with normal saline in a large animal model of multisystem trauma. J Trauma Acute Care Surg. 2014 Apr; 76(4):998-1007. PMID: 24662863.
    Citations: 12     Fields:    Translation:AnimalsCells
  19. Peev MP, Rago A, Hwabejire JO, Duggan MJ, Beagle J, Marini J, Zugates G, Busold R, Freyman T, Velmahos GS, Demoya MA, Yeh DD, Fagenholz PJ, Sharma U, King DR. Self-expanding foam for prehospital treatment of severe intra-abdominal hemorrhage: dose finding study. J Trauma Acute Care Surg. 2014 Mar; 76(3):619-23; discussion 623-4. PMID: 24553527.
    Citations: 7     Fields:    Translation:Animals
  20. Duggan MJ, Rago A, Marini J, Beagle J, Peev M, Velmahos G, Sharma U, King DR. Development of a lethal, closed-abdomen, arterial hemorrhage model in noncoagulopathic swine. J Surg Res. 2014 Apr; 187(2):536-41. PMID: 24398305.
    Citations: 3     Fields:    Translation:Animals
  21. Imam AM, Jin G, Sillesen M, Duggan M, Jepsen CH, Hwabejire JO, Lu J, Liu B, DeMoya MA, Velmahos GC, Alam HB. Early treatment with lyophilized plasma protects the brain in a large animal model of combined traumatic brain injury and hemorrhagic shock. J Trauma Acute Care Surg. 2013 Dec; 75(6):976-83. PMID: 24256669.
    Citations: 10     Fields:    Translation:Animals
  22. Hwabejire JO, Jin G, Imam AM, Duggan M, Sillesen M, Deperalta D, Jepsen CH, Lu J, Li Y, deMoya MA, Alam HB. Pharmacologic modulation of cerebral metabolic derangement and excitotoxicity in a porcine model of traumatic brain injury and hemorrhagic shock. Surgery. 2013 Aug; 154(2):234-43. PMID: 23889951.
    Citations: 16     Fields:    Translation:Animals
  23. Imam AM, Jin G, Duggan M, Sillesen M, Hwabejire JO, Jepsen CH, DePeralta D, Liu B, Lu J, deMoya MA, Socrate S, Alam HB. Synergistic effects of fresh frozen plasma and valproic acid treatment in a combined model of traumatic brain injury and hemorrhagic shock. Surgery. 2013 Aug; 154(2):388-96. PMID: 23889966.
    Citations: 16     Fields:    Translation:Animals
  24. Duggan M, Rago A, Sharma U, Zugates G, Freyman T, Busold R, Caulkins J, Pham Q, Chang Y, Mejaddam A, Beagle J, Velmahos G, deMoya M, Zukerberg L, Ng TF, King DR. Self-expanding polyurethane polymer improves survival in a model of noncompressible massive abdominal hemorrhage. J Trauma Acute Care Surg. 2013 Jun; 74(6):1462-7. PMID: 23694873.
    Citations: 13     Fields:    Translation:Animals
  25. Sillesen M, Johansson PI, Rasmussen LS, Jin G, Jepsen CH, Imam AM, Hwabejire J, Lu J, Duggan M, Velmahos G, deMoya M, Alam HB. Platelet activation and dysfunction in a large-animal model of traumatic brain injury and hemorrhage. J Trauma Acute Care Surg. 2013 May; 74(5):1252-9. PMID: 23609275.
    Citations: 25     Fields:    Translation:AnimalsCells
  26. Kasotakis G, Duggan M, Li Y, O'Dowd D, Baldwin K, de Moya MA, King DR, Alam HB, Velmahos G. Optimal pressure of abdominal gas insufflation for bleeding control in a severe swine splenic injury model. J Surg Res. 2013 Oct; 184(2):931-6. PMID: 23545409.
    Citations: 1     Fields:    Translation:Animals
  27. Jin G, Duggan M, Imam A, Demoya MA, Sillesen M, Hwabejire J, Jepsen CH, Liu B, Mejaddam AY, Lu J, Smith WM, Velmahos GC, Socrate S, Alam HB. Pharmacologic resuscitation for hemorrhagic shock combined with traumatic brain injury. J Trauma Acute Care Surg. 2012 Dec; 73(6):1461-70. PMID: 23188239.
    Citations: 22     Fields:    Translation:Animals
  28. Duggan MJ, Mejaddam AY, Beagle J, Demoya MA, Velmahosa GC, Alam HB, Rago A, Zugates G, Busold R, Freyman T, Sharma U, King DR. Development of a lethal, closed-abdomen grade V hepato-portal injury model in non-coagulopathic swine. J Surg Res. 2013 Jun 01; 182(1):101-7. PMID: 22921917.
    Citations: 6     Fields:    Translation:Animals
  29. Jin G, DeMoya MA, Duggan M, Knightly T, Mejaddam AY, Hwabejire J, Lu J, Smith WM, Kasotakis G, Velmahos GC, Socrate S, Alam HB. Traumatic brain injury and hemorrhagic shock: evaluation of different resuscitation strategies in a large animal model of combined insults. Shock. 2012 Jul; 38(1):49-56. PMID: 22575994.
    Citations: 28     Fields:    Translation:Animals
  30. Shuja F, Finkelstein RA, Fukudome E, Duggan M, Kheirbek T, Hamwi K, Fischer TH, Fikry K, deMoya M, Velmahos GC, Alam HB. Development and testing of low-volume hyperoncotic, hyperosmotic spray-dried plasma for the treatment of trauma-associated coagulopathy. J Trauma. 2011 Mar; 70(3):664-71. PMID: 21610357.
    Citations: 6     Fields:    Translation:Animals
  31. Alam HB, Hamwi KB, Duggan M, Fikry K, Lu J, Fukudome EY, Chong W, Bramos A, Kim K, Velmahos G. Hemostatic and pharmacologic resuscitation: results of a long-term survival study in a swine polytrauma model. J Trauma. 2011 Mar; 70(3):636-45. PMID: 21610354.
    Citations: 15     Fields:    Translation:Animals
  32. Duran-Struuck R, Cho PS, Teague AG, Fishman B, Fishman AS, Hanekamp JS, Moran SG, Wikiel KJ, Ferguson KK, Lo DP, Duggan M, Arn JS, Billiter B, Horner B, Houser S, Yeap BY, Westmoreland SV, Spitzer TR, McMorrow IM, Sachs DH, Bronson RT, Huang CA. Myelogenous leukemia in adult inbred MHC-defined miniature swine: a model for human myeloid leukemias. Vet Immunol Immunopathol. 2010 Jun 15; 135(3-4):243-56. PMID: 20079939.
    Citations: 10     Fields:    Translation:HumansAnimalsCells
  33. Alam HB, Bice LM, Butt MU, Cho SD, Dubick MA, Duggan M, Englehart MS, Holcomb JB, Morris MS, Prince MD, Schreiber MA, Shults C, Sondeen JL, Tabbara M, Tieu BH, Underwood SA. Testing of blood products in a polytrauma model: results of a multi-institutional randomized preclinical trial. J Trauma. 2009 Oct; 67(4):856-64. PMID: 19820596.
    Citations: 10     Fields:    Translation:Animals
  34. Alam HB, Shuja F, Butt MU, Duggan M, Li Y, Zacharias N, Fukudome EY, Liu B, Demoya M, Velmahos GC. Surviving blood loss without blood transfusion in a swine poly-trauma model. Surgery. 2009 Aug; 146(2):325-33. PMID: 19628092.
    Citations: 39     Fields:    Translation:AnimalsCells
  35. Velmahos GC, Tabbara M, Spaniolas K, Duggan M, Alam HB, Serra M, Sun L, de Luis J. Self-expanding hemostatic polymer for control of exsanguinating extremity bleeding. J Trauma. 2009 Apr; 66(4):984-8. PMID: 19359903.
    Citations: 1     Fields:    Translation:Animals
  36. Cho SD, Holcomb JB, Tieu BH, Englehart MS, Morris MS, Karahan ZA, Underwood SA, Muller PJ, Prince MD, Medina L, Sondeen J, Shults C, Duggan M, Tabbara M, Alam HB, Schreiber MA. Reproducibility of an animal model simulating complex combat-related injury in a multiple-institution format. Shock. 2009 Jan; 31(1):87-96. PMID: 18497710.
    Citations: 19     Fields:    Translation:HumansAnimals
  37. Shuja F, Shults C, Duggan M, Tabbara M, Butt MU, Fischer TH, Schreiber MA, Tieu B, Holcomb JB, Sondeen JL, Demoya M, Velmahos GC, Alam HB. Development and testing of freeze-dried plasma for the treatment of trauma-associated coagulopathy. J Trauma. 2008 Nov; 65(5):975-85. PMID: 19001961.
    Citations: 11     Fields:    Translation:Animals
  38. Alam HB, Duggan M, Li Y, Spaniolas K, Liu B, Tabbara M, Demoya M, Sailhamer EA, Shults C, Velmahos GC. Putting life on hold-for how long? Profound hypothermic cardiopulmonary bypass in a Swine model of complex vascular injuries. J Trauma. 2008 Apr; 64(4):912-22. PMID: 18404056.
    Citations: 11     Fields:    Translation:Animals
  39. Velmahos GC, Spaniolas K, Tabbara M, Duggan M, Li Y, De Moya M, Alam HB. Abdominal insufflation decreases blood loss without worsening the inflammatory response: implications for prehospital control of internal bleeding. Am Surg. 2008 Apr; 74(4):297-301. PMID: 18453291.
    Citations: 3     Fields:    Translation:Animals
  40. Pryor J, D'Arceuil H, Phil M, Liu J, He J, Gonzalez RG, Duggan M, De Crespigny A. Superselective intracerebral catheterization of a branch of the internal carotid artery coupled with magnetic resonance imaging. Interv Neuroradiol. 2007 Sep; 13(3):277-80. PMID: 20566119.
    Citations: 1     Fields:    
  41. Velmahos GC, Spaniolas K, Duggan M, Alam HB, Tabbara M, de Moya M, Vosburgh K. Abdominal insufflation for control of bleeding after severe splenic injury. J Trauma. 2007 Aug; 63(2):285-8; discussion 288-90. PMID: 17693825.
    Citations: 5     Fields:    Translation:Animals
  42. Liu Y, D'Arceuil HE, Westmoreland S, He J, Duggan M, Gonzalez RG, Pryor J, de Crespigny AJ. Serial diffusion tensor MRI after transient and permanent cerebral ischemia in nonhuman primates. Stroke. 2007 Jan; 38(1):138-45. PMID: 17122422.
    Citations: 47     Fields:    Translation:AnimalsCells
  43. D'Arceuil HE, Duggan M, He J, Pryor J, de Crespigny A. Middle cerebral artery occlusion in Macaca fascicularis: acute and chronic stroke evolution. J Med Primatol. 2006 Apr; 35(2):78-86. PMID: 16556294.
    Citations: 20     Fields:    Translation:Animals
  44. Chaddock JA, Purkiss JR, Alexander FC, Doward S, Fooks SJ, Friis LM, Hall YH, Kirby ER, Leeds N, Moulsdale HJ, Dickenson A, Green GM, Rahman W, Suzuki R, Duggan MJ, Quinn CP, Shone CC, Foster KA. Retargeted clostridial endopeptidases: inhibition of nociceptive neurotransmitter release in vitro, and antinociceptive activity in in vivo models of pain. Mov Disord. 2004 Mar; 19 Suppl 8:S42-7. PMID: 15027053.
    Citations: 18     Fields:    Translation:AnimalsCells
  45. Gollackner B, Dor FJ, Knosalla C, Buhler L, Duggan M, Huang CA, Houser SL, Sachs DH, Kawai T, Ko DS, Cooper DK. Spleen transplantation in miniature swine: surgical technique and results in major histocompatibility complex-matched donor and recipient pairs. Transplantation. 2003 Jun 15; 75(11):1799-806. PMID: 12811237.
    Citations: 4     Fields:    Translation:HumansAnimalsCells
  46. Duggan MJ, Quinn CP, Chaddock JA, Purkiss JR, Alexander FC, Doward S, Fooks SJ, Friis LM, Hall YH, Kirby ER, Leeds N, Moulsdale HJ, Dickenson A, Green GM, Rahman W, Suzuki R, Shone CC, Foster KA. Inhibition of release of neurotransmitters from rat dorsal root ganglia by a novel conjugate of a Clostridium botulinum toxin A endopeptidase fragment and Erythrina cristagalli lectin. J Biol Chem. 2002 Sep 20; 277(38):34846-52. PMID: 12105193.
    Citations: 38     Fields:    Translation:AnimalsCells
  47. Chaddock JA, Purkiss JR, Friis LM, Broadbridge JD, Duggan MJ, Fooks SJ, Shone CC, Quinn CP, Foster KA. Inhibition of vesicular secretion in both neuronal and nonneuronal cells by a retargeted endopeptidase derivative of Clostridium botulinum neurotoxin type A. Infect Immun. 2000 May; 68(5):2587-93. PMID: 10768948.
    Citations: 18     Fields:    Translation:AnimalsCells
  48. Chaddock JA, Purkiss JR, Duggan MJ, Quinn CP, Shone CC, Foster KA. A conjugate composed of nerve growth factor coupled to a non-toxic derivative of Clostridium botulinum neurotoxin type A can inhibit neurotransmitter release in vitro. Growth Factors. 2000; 18(2):147-55. PMID: 11019785.
    Citations: 17     Fields:    Translation:AnimalsCells
  49. Snook B, Duggan M, Birkett D. Sarcoidosis of the pancreas: a case report. Am Surg. 1996 Nov; 62(11):947-8. PMID: 8895719.
    Citations: 2     Fields:    Translation:Humans
  50. Boyd RS, Duggan MJ, Shone CC, Foster KA. The effect of botulinum neurotoxins on the release of insulin from the insulinoma cell lines HIT-15 and RINm5F. J Biol Chem. 1995 Aug 04; 270(31):18216-8. PMID: 7629139.
    Citations: 11     Fields:    Translation:Cells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.