Harvard Catalyst Profiles

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Susan N. Chi, M.D.


Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Blandin AF, Giglio R, Graham MS, Garcia G, Malinowski S, Woods JK, Ramkissoon S, Ramkissoon L, Dubois F, Schoolcraft K, Tsai J, Wang D, Jones R, Vogelzang J, Pelton K, Becker S, Watkinson F, Sinai C, Cohen EF, Booker MA, Tolstorukov MY, Haemels V, Goumnerova L, Wright K, Kieran M, Fehnel K, Reardon D, Tauziède-Espariat A, Lulla R, Carcamo B, Chaleff S, Charest A, De Smet F, Ligon AH, Dubuc A, Pages M, Varlet P, Wen PY, Alexander BM, Chi S, Alexandrescu S, Kittler R, Bachoo R, Bandopadhayay P, Beroukhim R, Ligon KL. ALK amplification and rearrangements are recurrent targetable events in congenital and adult glioblastoma. Clin Cancer Res. 2023 Feb 13. PMID: 36780194.
    Citations:    Fields:    
  2. Alva E, Rubens J, Chi S, Rosenberg T, Reddy A, Raabe EH, Margol A. Recent progress and novel approaches to treating atypical teratoid rhabdoid tumor. Neoplasia. 2023 03; 37:100880. PMID: 36773516; PMCID: PMC9929860.
    Citations:    Fields:    
  3. Oppel F, Shao S, Gendreizig S, Zimmerman MW, Schürmann M, Flavian VF, Goon P, Chi SN, Aster JC, Sudhoff H, Look AT. p53 Pathway Inactivation Drives SMARCB1-deficient p53-wildtype Epithelioid Sarcoma Onset Indicating Therapeutic Vulnerability Through MDM2 Inhibition. Mol Cancer Ther. 2022 11 03; 21(11):1689-1700. PMID: 36099437.
    Citations:    Fields:    Translation:HumansAnimals
  4. Rosenberg T, Yeo KK, Mauguen A, Alexandrescu S, Prabhu SP, Tsai JW, Malinowski S, Joshirao M, Parikh K, Farouk Sait S, Rosenblum MK, Benhamida JK, Michaiel G, Tran HN, Dahiya S, Kachurak K, Friedman GK, Krystal JI, Huang MA, Margol AS, Wright KD, Aguilera D, MacDonald TJ, Chi SN, Karajannis MA. Upfront molecular targeted therapy for the treatment of BRAF-mutant pediatric high-grade glioma. Neuro Oncol. 2022 11 02; 24(11):1964-1975. PMID: 35397478; PMCID: PMC9629451.
    Citations:    Fields:    
  5. Woods JK, Lidov HG, Ligon KL, Santagata S, Chi SN, Yeo KK, Alexandrescu S. PD-L1 and PD-1 expression in pediatric central nervous system germ cell tumors. Mod Pathol. 2022 12; 35(12):1770-1774. PMID: 36057740.
    Citations:    Fields:    Translation:Humans
  6. Plant-Fox AS, Suzuki T, Diaz Coronado RY, Epelman S, Sakamoto L, Cheng S, Yanagisawa T, Rosner B, Chi SN, Kieran MW. An international study evaluating the epidemiology of intracranial germ cell tumors in the native versus immigrant Japanese populations: the need for an international registry. J Neurooncol. 2022 Sep; 159(3):563-570. PMID: 35918506.
    Citations:    Fields:    Translation:Humans
  7. Dubois FPB, Shapira O, Greenwald NF, Zack T, Wala J, Tsai JW, Crane A, Baguette A, Hadjadj D, Harutyunyan AS, Kumar KH, Blattner-Johnson M, Vogelzang J, Sousa C, Kang KS, Sinai C, Wang DK, Khadka P, Lewis K, Nguyen L, Malkin H, Ho P, O'Rourke R, Zhang S, Gold R, Deng D, Serrano J, Snuderl M, Jones C, Wright KD, Chi SN, Grill J, Kleinman CL, Goumnerova LC, Jabado N, Jones DTW, Kieran MW, Ligon KL, Beroukhim R, Bandopadhayay P. Structural variants shape driver combinations and outcomes in pediatric high-grade glioma. Nat Cancer. 2022 08; 3(8):994-1011. PMID: 35788723.
    Citations: 1     
  8. Mueller S, Taitt JM, Villanueva-Meyer JE, Bonner ER, Nejo T, Lulla RR, Goldman S, Banerjee A, Chi SN, Whipple NS, Crawford JR, Gauvain K, Nazemi KJ, Watchmaker PB, Almeida ND, Okada K, Salazar AM, Gilbert RD, Nazarian J, Molinaro AM, Butterfield LH, Prados MD, Okada H. Mass cytometry detects H3.3K27M-specific vaccine responses in diffuse midline glioma. J Clin Invest. 2022 06 15; 132(12). PMID: 35703183; PMCID: PMC9203080.
    Citations:    Fields:    Translation:Humans
  9. Liu KX, Shang HH, Cacciotti C, Everdell E, Aizer AA, Rahman R, Malinowski S, Meredith DM, Kamihara J, Wen PY, Ligon KL, Chi SN, Marcus KJ, Yeo KK, Alexandrescu S, Haas-Kogan DA. DICER1 mutations in primary central nervous system tumors: new insights into histologies, mutations, and prognosis. J Neurooncol. 2022 May; 157(3):499-510. PMID: 35384518.
    Citations:    Fields:    Translation:Humans
  10. Rao R, Koehler A, Rothman Y, Turner B, Denlinger J, Erickson M, Hagen M, Braverman TS, Mahammedi A, Golnik K, Zuccarello M, Gozal YM, Broun ER, Chi SN, Sengupta S. Pearls & Oy-sters: Pivoting Treatment Regimens of Pediatric Atypical Teratoid Rhabdoid Tumors to Optimize Care in Adult ATRT: A Case Report. Neurology. 2022 04 26; 98(17):726-730. PMID: 35256482.
    Citations:    Fields:    Translation:Humans
  11. Plant-Fox AS, Ma C, Al-Sayegh H, Shyr D, Lee MA, Lehmann LE, Chi SN. Comparison of toxicity following single versus tandem autologous transplant regimens for pediatric medulloblastoma. Pediatr Transplant. 2022 06; 26(4):e14229. PMID: 35083822.
    Citations:    Fields:    Translation:Humans
  12. Bandopadhayay P, Chi SN. The challenges in treating embryonal tumors with multilayered rosettes (ETMR) and other infant brain tumors. Neuro Oncol. 2022 01 05; 24(1):138-140. PMID: 34477207; PMCID: PMC8730765.
    Citations:    Fields:    Translation:Humans
  13. Graham RT, Abu-Arja MH, Stanek JR, Cappellano A, Coleman C, Chi S, Cooney T, Dhall G, Ellen JG, Finlay JL, Fisher MJ, Friedman GK, Gajjar A, Gauvain K, Hoffman LM, Hukin J, Lucas JT, Mueller S, Navalkele P, Ronsley R, Tinkle C, Villeneuve S, Yeo KK, Su JM, Margol A, Gottardo NG, Allen J, Packer R, Bartels U, Abdelbaki MS. Multi-institutional analysis of treatment modalities in basal ganglia and thalamic germinoma. Pediatr Blood Cancer. 2021 10; 68(10):e29172. PMID: 34125480; PMCID: PMC9639702.
    Citations:    Fields:    Translation:Humans
  14. Levy AS, Krailo M, Chi S, Villaluna D, Springer L, Williams-Hughes C, Fouladi M, Gajjar A. Temozolomide with irinotecan versus temozolomide, irinotecan plus bevacizumab for recurrent medulloblastoma of childhood: Report of a COG randomized Phase II screening trial. Pediatr Blood Cancer. 2021 08; 68(8):e29031. PMID: 33844469; PMCID: PMC8764558.
    Citations: 7     Fields:    Translation:HumansCTClinical Trials
  15. Shulman DS, Kiwinda LV, Edwards S, Clinton CM, Hunt S, Greenspan L, Lawler KD, Reaman G, Al-Sayegh H, Bona K, O'Neill AF, Shusterman S, Janeway KA, Place AE, Chi SN, Ma C, DuBois SG. Retrospective evaluation of single patient investigational new drug (IND) requests in pediatric oncology. Cancer Med. 2021 Apr; 10(7):2310-2318. PMID: 33751835; PMCID: PMC7982629.
    Citations:    Fields:    
  16. Tsai JW, Manoharan N, Alexandrescu S, Zimmerman MA, Scully J, Chordas C, Clymer J, Wright KD, Filbin M, Ullrich NJ, Marcus KJ, Haas-Kogan D, Chi SN, Bandopadhayay P, Yeo KK. Outcomes after first relapse of childhood intracranial ependymoma. Pediatr Blood Cancer. 2021 08; 68(8):e28930. PMID: 33565268.
    Citations: 4     Fields:    Translation:Humans
  17. Mueller S, Taitt JM, Villanueva-Meyer JE, Bonner ER, Nejo T, Lulla RR, Goldman S, Banerjee A, Chi SN, Whipple NS, Crawford JR, Gauvain K, Nazemi KJ, Watchmaker PB, Almeida ND, Okada K, Salazar AM, Gilbert RD, Nazarian J, Molinaro AM, Butterfield LH, Prados MD, Okada H. Mass cytometry detects H3.3K27M-specific vaccine responses in diffuse midline glioma. J Clin Invest. 2020 12 01; 130(12):6325-6337. PMID: 32817593; PMCID: PMC7685729.
    Citations: 19     Fields:    Translation:HumansCellsCTClinical Trials
  18. Wright KD, Yao X, London WB, Kao PC, Gore L, Hunger S, Geyer R, Cohen KJ, Allen JC, Katzenstein HM, Smith A, Boklan J, Nazemi K, Trippett T, Karajannis M, Herzog C, Destefano J, Direnzo J, Pietrantonio J, Greenspan L, Cassidy D, Schissel D, Perentesis J, Basu M, Mizuno T, Vinks AA, Prabhu SP, Chi SN, Kieran MW. A POETIC Phase II study of continuous oral everolimus in recurrent, radiographically progressive pediatric low-grade glioma. Pediatr Blood Cancer. 2021 02; 68(2):e28787. PMID: 33140540; PMCID: PMC9161236.
    Citations: 1     Fields:    Translation:HumansCTClinical Trials
  19. Ullrich NJ, Prabhu SP, Reddy AT, Fisher MJ, Packer R, Goldman S, Robison NJ, Gutmann DH, Viskochil DH, Allen JC, Korf B, Cantor A, Cutter G, Thomas C, Perentesis JP, Mizuno T, Vinks AA, Manley PE, Chi SN, Kieran MW. A phase II study of continuous oral mTOR inhibitor everolimus for recurrent, radiographic-progressive neurofibromatosis type 1-associated pediatric low-grade glioma: a Neurofibromatosis Clinical Trials Consortium study. Neuro Oncol. 2020 10 14; 22(10):1527-1535. PMID: 32236425; PMCID: PMC7566451.
    Citations: 10     Fields:    Translation:HumansCTClinical Trials
  20. Hanson D, Hoffman LM, Nagabushan S, Goumnerova LC, Rathmann A, Vogel T, Ziegler DS, Chi S. A modified IRS-III chemotherapy regimen leads to prolonged survival in children with embryonal tumor with multilayer rosettes. Neurooncol Adv. 2020 Jan-Dec; 2(1):vdaa120. PMID: 33196040; PMCID: PMC7648589.
    Citations: 2     
  21. Manoharan N, Choi J, Chordas C, Zimmerman MA, Scully J, Clymer J, Filbin M, Ullrich NJ, Bandopadhayay P, Chi SN, Yeo KK. Trametinib for the treatment of recurrent/progressive pediatric low-grade glioma. J Neurooncol. 2020 Sep; 149(2):253-262. PMID: 32780261.
    Citations: 9     Fields:    Translation:Humans
  22. Hoffman LM, Richardson EA, Ho B, Margol A, Reddy A, Lafay-Cousin L, Chi S, Slavc I, Judkins A, Hasselblatt M, Bourdeaut F, Frühwald MC, Vibhakar R, Bouffet E, Huang A. Advancing biology-based therapeutic approaches for atypical teratoid rhabdoid tumors. Neuro Oncol. 2020 07 07; 22(7):944-954. PMID: 32129445.
    Citations: 7     Fields:    Translation:Humans
  23. Cacciotti C, Choi J, Alexandrescu S, Zimmerman MA, Cooney TM, Chordas C, Clymer J, Chi S, Yeo KK. Immune checkpoint inhibition for pediatric patients with recurrent/refractory CNS tumors: a single institution experience. J Neurooncol. 2020 Aug; 149(1):113-122. PMID: 32627129.
    Citations: 7     Fields:    Translation:HumansCTClinical Trials
  24. Touat M, Li YY, Boynton AN, Spurr LF, Iorgulescu JB, Bohrson CL, Cortes-Ciriano I, Birzu C, Geduldig JE, Pelton K, Lim-Fat MJ, Pal S, Ferrer-Luna R, Ramkissoon SH, Dubois F, Bellamy C, Currimjee N, Bonardi J, Qian K, Ho P, Malinowski S, Taquet L, Jones RE, Shetty A, Chow KH, Sharaf R, Pavlick D, Albacker LA, Younan N, Baldini C, Verreault M, Giry M, Guillerm E, Ammari S, Beuvon F, Mokhtari K, Alentorn A, Dehais C, Houillier C, Laigle-Donadey F, Psimaras D, Lee EQ, Nayak L, McFaline-Figueroa JR, Carpentier A, Cornu P, Capelle L, Mathon B, Barnholtz-Sloan JS, Chakravarti A, Bi WL, Chiocca EA, Fehnel KP, Alexandrescu S, Chi SN, Haas-Kogan D, Batchelor TT, Frampton GM, Alexander BM, Huang RY, Ligon AH, Coulet F, Delattre JY, Hoang-Xuan K, Meredith DM, Santagata S, Duval A, Sanson M, Cherniack AD, Wen PY, Reardon DA, Marabelle A, Park PJ, Idbaih A, Beroukhim R, Bandopadhayay P, Bielle F, Ligon KL. Mechanisms and therapeutic implications of hypermutation in gliomas. Nature. 2020 04; 580(7804):517-523. PMID: 32322066; PMCID: PMC8235024.
    Citations: 130     Fields:    Translation:HumansAnimalsCells
  25. Forrest SJ, Al-Ibraheemi A, Doan D, Ward A, Clinton CM, Putra J, Pinches RS, Kadoch C, Chi SN, DuBois SG, Leavey PJ, LeBoeuf NR, Mullen E, Collins N, Church AJ, Janeway KA. Genomic and Immunologic Characterization of INI1-Deficient Pediatric Cancers. Clin Cancer Res. 2020 06 15; 26(12):2882-2890. PMID: 32122923.
    Citations: 6     Fields:    Translation:Humans
  26. Ahrendsen JT, Filbin MG, Chi SN, Manley PE, Wright KD, Bandopadhayay P, Clymer JR, Yeo KK, Kieran MW, Jones R, Lidov HG, Ligon KL, Alexandrescu S. Increasing value of autopsies in patients with brain tumors in the molecular era. J Neurooncol. 2019 Nov; 145(2):349-355. PMID: 31571114.
    Citations: 1     Fields:    Translation:Humans
  27. Bitterman DS, MacDonald SM, Yock TI, Tarbell NJ, Wright KD, Chi SN, Marcus KJ, Haas-Kogan DA. Revisiting the Role of Radiation Therapy for Pediatric Low-Grade Glioma. J Clin Oncol. 2019 12 10; 37(35):3335-3339. PMID: 31498029; PMCID: PMC9798905.
    Citations: 9     Fields:    Translation:Humans
  28. Cooney T, Yeo KK, Kline C, Prados M, Haas-Kogan D, Chi S, Mueller S. Neuro-Oncology Practice Clinical Debate: targeted therapy vs conventional chemotherapy in pediatric low-grade glioma. Neurooncol Pract. 2020 Jan; 7(1):4-10. PMID: 32257279.
    Citations: 5     
  29. Miklja Z, Pasternak A, Stallard S, Nicolaides T, Kline-Nunnally C, Cole B, Beroukhim R, Bandopadhayay P, Chi S, Ramkissoon SH, Mullan B, Bruzek AK, Gauthier A, Garcia T, Atchison C, Marini B, Fouladi M, Parsons DW, Leary S, Mueller S, Ligon KL, Koschmann C. Molecular profiling and targeted therapy in pediatric gliomas: review and consensus recommendations. Neuro Oncol. 2019 08 05; 21(8):968-980. PMID: 30805642.
    Citations: 22     Fields:    Translation:Humans
  30. Bitterman DS, Chi SN, Haas-Kogan DA. A Central Role of Radiation Therapy in Central Nervous System Germinoma. Int J Radiat Oncol Biol Phys. 2019 08 01; 104(5):970-971. PMID: 31327428.
    Citations:    Fields:    Translation:Humans
  31. Kieran MW, Goumnerova L, Manley P, Chi SN, Marcus KJ, Manzanera AG, Polanco MLS, Guzik BW, Aguilar-Cordova E, Diaz-Montero CM, DiPatri AJ, Tomita T, Lulla R, Greenspan L, Aguilar LK, Goldman S. Phase I study of gene-mediated cytotoxic immunotherapy with AdV-tk as adjuvant to surgery and radiation for pediatric malignant glioma and recurrent ependymoma. Neuro Oncol. 2019 03 18; 21(4):537-546. PMID: 30883662; PMCID: PMC6422437.
    Citations: 28     Fields:    Translation:HumansCellsCTClinical Trials
  32. Hong AL, Tseng YY, Wala JA, Kim WJ, Kynnap BD, Doshi MB, Kugener G, Sandoval GJ, Howard TP, Li J, Yang X, Tillgren M, Ghandi M, Sayeed A, Deasy R, Ward A, McSteen B, Labella KM, Keskula P, Tracy A, Connor C, Clinton CM, Church AJ, Crompton BD, Janeway KA, Van Hare B, Sandak D, Gjoerup O, Bandopadhayay P, Clemons PA, Schreiber SL, Root DE, Gokhale PC, Chi SN, Mullen EA, Roberts CW, Kadoch C, Beroukhim R, Ligon KL, Boehm JS, Hahn WC. Renal medullary carcinomas depend upon SMARCB1 loss and are sensitive to proteasome inhibition. Elife. 2019 03 12; 8. PMID: 30860482.
    Citations: 19     Fields:    Translation:HumansAnimalsCells
  33. Song H, Zhong CS, Kieran MW, Chi SN, Wright KD, Huang JT. Cutaneous reactions to targeted therapies in children with CNS tumors: A cross-sectional study. Pediatr Blood Cancer. 2019 06; 66(6):e27682. PMID: 30821092.
    Citations:    Fields:    Translation:Humans
  34. Song H, Dzuali F, Chi SN, Treat JR, Huang JT. Improvement of hereditary palmoplantar keratoderma with oral trametinib. Pediatr Dermatol. 2019 Jan; 36(1):e48-e49. PMID: 30548577.
    Citations: 1     Fields:    Translation:Humans
  35. Gupta N, Goumnerova LC, Manley P, Chi SN, Neuberg D, Puligandla M, Fangusaro J, Goldman S, Tomita T, Alden T, DiPatri A, Rubin JB, Gauvain K, Limbrick D, Leonard J, Geyer JR, Leary S, Browd S, Wang Z, Sood S, Bendel A, Nagib M, Gardner S, Karajannis MA, Harter D, Ayyanar K, Gump W, Bowers DC, Weprin B, MacDonald TJ, Aguilera D, Brahma B, Robison NJ, Kiehna E, Krieger M, Sandler E, Aldana P, Khatib Z, Ragheb J, Bhatia S, Mueller S, Banerjee A, Bredlau AL, Gururangan S, Fuchs H, Cohen KJ, Jallo G, Dorris K, Handler M, Comito M, Dias M, Nazemi K, Baird L, Murray J, Lindeman N, Hornick JL, Malkin H, Sinai C, Greenspan L, Wright KD, Prados M, Bandopadhayay P, Ligon KL, Kieran MW. Prospective feasibility and safety assessment of surgical biopsy for patients with newly diagnosed diffuse intrinsic pontine glioma. Neuro Oncol. 2018 10 09; 20(11):1547-1555. PMID: 29741745; PMCID: PMC6176802.
    Citations: 38     Fields:    Translation:Humans
  36. Manley PE, Trippett T, Smith AA, Macy ME, Leary SES, Boklan J, Cohen KJ, Goldman S, Kilburn LB, Dhall G, Devin J, Herzog CE, Partap S, Fauchet F, Badreddine E, Bernard JP, Chi SN. A phase 1/2 dose-finding, safety, and activity study of cabazitaxel in pediatric patients with refractory solid tumors including tumors of the central nervous system. Pediatr Blood Cancer. 2018 09; 65(9):e27217. PMID: 29750396.
    Citations: 2     Fields:    Translation:HumansCTClinical Trials
  37. Marinoff AE, Ma C, Guo D, Snuderl M, Wright KD, Manley PE, Al-Sayegh H, Sinai CE, Ullrich NJ, Marcus K, Haas-Kogan D, Goumnerova L, London WB, Kieran MW, Chi SN, Fangusaro J, Bandopadhayay P. Rethinking childhood ependymoma: a retrospective, multi-center analysis reveals poor long-term overall survival. J Neurooncol. 2017 Oct; 135(1):201-211. PMID: 28733870; PMCID: PMC5658456.
    Citations: 32     Fields:    Translation:Humans
  38. Ramkissoon SH, Bandopadhayay P, Hwang J, Ramkissoon LA, Greenwald NF, Schumacher SE, O'Rourke R, Pinches N, Ho P, Malkin H, Sinai C, Filbin M, Plant A, Bi WL, Chang MS, Yang E, Wright KD, Manley PE, Ducar M, Alexandrescu S, Lidov H, Delalle I, Goumnerova LC, Church AJ, Janeway KA, Harris MH, MacConaill LE, Folkerth RD, Lindeman NI, Stiles CD, Kieran MW, Ligon AH, Santagata S, Dubuc AM, Chi SN, Beroukhim R, Ligon KL. Clinical targeted exome-based sequencing in combination with genome-wide copy number profiling: precision medicine analysis of 203 pediatric brain tumors. Neuro Oncol. 2017 Jul 01; 19(7):986-996. PMID: 28104717; PMCID: PMC5570190.
    Citations: 36     Fields:    Translation:Humans
  39. Macy ME, Kieran MW, Chi SN, Cohen KJ, MacDonald TJ, Smith AA, Etzl MM, Kuei MC, Donson AM, Gore L, DiRenzo J, Trippett TM, Ostrovnaya I, Narendran A, Foreman NK, Dunkel IJ. A pediatric trial of radiation/cetuximab followed by irinotecan/cetuximab in newly diagnosed diffuse pontine gliomas and high-grade astrocytomas: A Pediatric Oncology Experimental Therapeutics Investigators' Consortium study. Pediatr Blood Cancer. 2017 Nov; 64(11). PMID: 28544128; PMCID: PMC5605460.
    Citations: 2     Fields:    Translation:Humans
  40. Geoerger B, Bourdeaut F, DuBois SG, Fischer M, Geller JI, Gottardo NG, Marabelle A, Pearson ADJ, Modak S, Cash T, Robinson GW, Motta M, Matano A, Bhansali SG, Dobson JR, Parasuraman S, Chi SN. A Phase I Study of the CDK4/6 Inhibitor Ribociclib (LEE011) in Pediatric Patients with Malignant Rhabdoid Tumors, Neuroblastoma, and Other Solid Tumors. Clin Cancer Res. 2017 May 15; 23(10):2433-2441. PMID: 28432176.
    Citations: 48     Fields:    Translation:HumansCTClinical Trials
  41. Fay-McClymont TB, Ploetz DM, Mabbott D, Walsh K, Smith A, Chi SN, Wells E, Madden J, Margol A, Finlay J, Kieran MW, Strother D, Dhall G, Packer RJ, Foreman NK, Bouffet E, Lafay-Cousin L. Long-term neuropsychological follow-up of young children with medulloblastoma treated with sequential high-dose chemotherapy and irradiation sparing approach. J Neurooncol. 2017 05; 133(1):119-128. PMID: 28405869.
    Citations: 12     Fields:    Translation:Humans
  42. Seibel NL, Janeway K, Allen CE, Chi SN, Cho YJ, Glade Bender JL, Kim A, Laetsch TW, Irwin MS, Takebe N, Tricoli JV, Parsons DW. Pediatric oncology enters an era of precision medicine. Curr Probl Cancer. 2017 May - Jun; 41(3):194-200. PMID: 28343740.
    Citations: 16     Fields:    Translation:Humans
  43. Plant AS, Chi SN, Frazier L. Pediatric malignant germ cell tumors: A comparison of the neuro-oncology and solid tumor experience. Pediatr Blood Cancer. 2016 12; 63(12):2086-2095. PMID: 27554756.
    Citations: 1     Fields:    Translation:Humans
  44. Zacharoulis S, Morales La Madrid A, Bandopadhayay P, Chi SN, Manley P, Ullrich NN, Marcus K, Goumnerova L, Scott RM, Proctor M, Young-Poussaint T, De Girolami U, Kieran MW. Central Versus Extraventricular Neurocytoma in Children: A Clinicopathologic Comparison and Review of the Literature. J Pediatr Hematol Oncol. 2016 08; 38(6):479-85. PMID: 27438020.
    Citations: 3     Fields:    Translation:Humans
  45. Lafay-Cousin L, Smith A, Chi SN, Wells E, Madden J, Margol A, Ramaswamy V, Finlay J, Taylor MD, Dhall G, Strother D, Kieran MW, Foreman NK, Packer RJ, Bouffet E. Clinical, Pathological, and Molecular Characterization of Infant Medulloblastomas Treated with Sequential High-Dose Chemotherapy. Pediatr Blood Cancer. 2016 09; 63(9):1527-34. PMID: 27145464.
    Citations: 35     Fields:    Translation:Humans
  46. Dodgshun AJ, SantaCruz N, Hwang J, Ramkissoon SH, Malkin H, Bergthold G, Manley P, Chi S, MacGregor D, Goumnerova L, Sullivan M, Ligon K, Beroukhim R, Herrington B, Kieran MW, Hansford JR, Bandopadhayay P. Disseminated glioneuronal tumors occurring in childhood: treatment outcomes and BRAF alterations including V600E mutation. J Neurooncol. 2016 06; 128(2):293-302. PMID: 26994902.
    Citations: 22     Fields:    Translation:Humans
  47. Santacroce E, Zimmerman MA, Freeman M, Lau Greenberg T, Nguyen P, Chi SN, Bandopadhayay P, Lane S, Szabatura A, Houlahan K, Billett A. Building a new process: Nursing verification of pediatric oral chemotherapy. J Clin Oncol. 2016 Mar; 34(7_suppl):199. PMID: 28152843.
  48. Frühwald MC, Biegel JA, Bourdeaut F, Roberts CW, Chi SN. Atypical teratoid/rhabdoid tumors-current concepts, advances in biology, and potential future therapies. Neuro Oncol. 2016 06; 18(6):764-78. PMID: 26755072; PMCID: PMC4864253.
    Citations: 61     Fields:    Translation:Humans
  49. Bandopadhayay P, Silvera VM, Ciarlini PDSC, Malkin H, Bi WL, Bergthold G, Faisal AM, Ullrich NJ, Marcus K, Scott RM, Beroukhim R, Manley PE, Chi SN, Ligon KL, Goumnerova LC, Kieran MW. Myxopapillary ependymomas in children: imaging, treatment and outcomes. J Neurooncol. 2016 Jan; 126(1):165-174. PMID: 26468139.
    Citations: 9     Fields:    Translation:Humans
  50. Alexander S, Pole JD, Gibson P, Lee M, Hesser T, Chi SN, Dvorak CC, Fisher B, Hasle H, Kanerva J, Möricke A, Phillips B, Raetz E, Rodriguez-Galindo C, Samarasinghe S, Schmiegelow K, Tissing W, Lehrnbecher T, Sung L. Classification of treatment-related mortality in children with cancer: a systematic assessment. Lancet Oncol. 2015 Dec; 16(16):e604-10. PMID: 26678213.
    Citations: 19     Fields:    Translation:Humans
  51. Kieran MW, Chi S, Goldman S, Onar-Thomas A, Poussaint TY, Vajapeyam S, Fahey F, Wu S, Turner DC, Stewart CF, Moses M, Packer RJ, Jakacki R, Banerjee A, Boyett JM, Fouladi M, Kun L. A phase I trial and PK study of cediranib (AZD2171), an orally bioavailable pan-VEGFR inhibitor, in children with recurrent or refractory primary CNS tumors. Childs Nerv Syst. 2015 Sep; 31(9):1433-45. PMID: 26188774.
    Citations: 8     Fields:    Translation:HumansCTClinical Trials
  52. Bourdeaut F, Chi SN, Frühwald MC. Rhabdoid tumors: integrating biological insights with clinical success: a report from the SMARCB1 and Rhabdoid Tumor Symposium, Paris, December 12-14, 2013. Cancer Genet. 2014 Sep; 207(9):346-51. PMID: 25468731.
    Citations: 5     Fields:    Translation:Humans
  53. Kim AH, Thompson EA, Governale LS, Santa C, Cahll K, Kieran MW, Chi SN, Ullrich NJ, Scott RM, Goumnerova LC. Recurrence after gross-total resection of low-grade pediatric brain tumors: the frequency and timing of postoperative imaging. J Neurosurg Pediatr. 2014 Oct; 14(4):356-64. PMID: 25062303.
    Citations: 9     Fields:    Translation:Humans
  54. Goldman S, Fangusaro J, Lulla R, Chi S, Manley P, Robison N, Kroon HA, Kieran M. Phase I individual dose titration trial of the human corticotropin-releasing factor (hcrf), corticorelin acetate injection (xerecept) in pediatric patients with peritumoral edema of the brain. Neuro Oncol. 2014 Jul; 16 Suppl 3:iii23. PMID: 25165250.
  55. Bandopadhayay P, Bergthold G, London WB, Goumnerova LC, Morales La Madrid A, Marcus KJ, Guo D, Ullrich NJ, Robison NJ, Chi SN, Beroukhim R, Kieran MW, Manley PE. Long-term outcome of 4,040 children diagnosed with pediatric low-grade gliomas: an analysis of the Surveillance Epidemiology and End Results (SEER) database. Pediatr Blood Cancer. 2014 Jul; 61(7):1173-9. PMID: 24482038.
    Citations: 83     Fields:    Translation:HumansCTClinical Trials
  56. Robison NJ, Campigotto F, Chi SN, Manley PE, Turner CD, Zimmerman MA, Chordas CA, Werger AM, Allen JC, Goldman S, Rubin JB, Isakoff MS, Pan WJ, Khatib ZA, Comito MA, Bendel AE, Pietrantonio JB, Kondrat L, Hubbs SM, Neuberg DS, Kieran MW. A phase II trial of a multi-agent oral antiangiogenic (metronomic) regimen in children with recurrent or progressive cancer. Pediatr Blood Cancer. 2014 Apr; 61(4):636-42. PMID: 24123865.
    Citations: 55     Fields:    Translation:HumansCTClinical Trials
  57. Robison NJ, Prabhu SP, Sun P, Chi SN, Kieran MW, Manley PE, Cohen LE, Goumnerova L, Smith ER, Scott RM, London WB, Ullrich NJ. Predictors of neoplastic disease in children with isolated pituitary stalk thickening. Pediatr Blood Cancer. 2013 Oct; 60(10):1630-5. PMID: 23670879.
    Citations: 6     Fields:    Translation:HumansCTClinical Trials
  58. Singh A, Lun X, Jayanthan A, Obaid H, Ruan Y, Strother D, Chi SN, Smith A, Forsyth P, Narendran A. Profiling pathway-specific novel therapeutics in preclinical assessment for central nervous system atypical teratoid rhabdoid tumors (CNS ATRT): favorable activity of targeting EGFR- ErbB2 signaling with lapatinib. Mol Oncol. 2013 Jun; 7(3):497-512. PMID: 23375777.
    Citations: 21     Fields:    Translation:HumansAnimalsCells
  59. Kieran MW, Roberts CW, Chi SN, Ligon KL, Rich BE, Macconaill LE, Garraway LA, Biegel JA. Absence of oncogenic canonical pathway mutations in aggressive pediatric rhabdoid tumors. Pediatr Blood Cancer. 2012 Dec 15; 59(7):1155-7. PMID: 22997201.
    Citations: 31     Fields:    Translation:HumansCells
  60. Manley PE, McKendrick K, McGillicudy M, Chi SN, Kieran MW, Cohen LE, Kothare S, Michael Scott R, Goumnerova LC, Sun P, London W, Marcus KJ, Pomeroy SL, Ullrich NJ. Sleep dysfunction in long term survivors of craniopharyngioma. J Neurooncol. 2012 Jul; 108(3):543-9. PMID: 22528788.
    Citations: 17     Fields:    Translation:Humans
  61. Fleming AJ, Chi SN. Brain tumors in children. Curr Probl Pediatr Adolesc Health Care. 2012 Apr; 42(4):80-103. PMID: 22433905.
    Citations: 20     Fields:    Translation:Humans
  62. Paugh BS, Broniscer A, Qu C, Miller CP, Zhang J, Tatevossian RG, Olson JM, Geyer JR, Chi SN, da Silva NS, Onar-Thomas A, Baker JN, Gajjar A, Ellison DW, Baker SJ. Genome-wide analyses identify recurrent amplifications of receptor tyrosine kinases and cell-cycle regulatory genes in diffuse intrinsic pontine glioma. J Clin Oncol. 2011 Oct 20; 29(30):3999-4006. PMID: 21931021.
    Citations: 159     Fields:    Translation:Humans
  63. Broniscer A, Baker JN, Baker SJ, Chi SN, Geyer JR, Morris EB, Gajjar A. Prospective collection of tissue samples at autopsy in children with diffuse intrinsic pontine glioma. Cancer. 2010 Oct 01; 116(19):4632-7. PMID: 20589749; PMCID: PMC2989604.
    Citations: 47     Fields:    Translation:HumansCTClinical Trials
  64. Wong JM, Chi SN, Marcus KJ, Levine BS, Ullrich NJ, MacDonald S, Lechpammer M, Goumnerova LC. Germinoma with malignant transformation to nongerminomatous germ cell tumor. J Neurosurg Pediatr. 2010 Sep; 6(3):295-8. PMID: 20809716.
    Citations: 4     Fields:    Translation:Humans
  65. Gururangan S, Chi SN, Young Poussaint T, Onar-Thomas A, Gilbertson RJ, Vajapeyam S, Friedman HS, Packer RJ, Rood BN, Boyett JM, Kun LE. Lack of efficacy of bevacizumab plus irinotecan in children with recurrent malignant glioma and diffuse brainstem glioma: a Pediatric Brain Tumor Consortium study. J Clin Oncol. 2010 Jun 20; 28(18):3069-75. PMID: 20479404.
    Citations: 89     Fields:    Translation:HumansCellsCTClinical Trials
  66. Zacharoulis S, Chi S, Kadota R, Kieran M. Biological modification strategies following marrow ablative, high-dose chemotherapy (HDCT) with autologous hematopoietic stem cell rescue (AHSCR) for pediatric brain tumors. Pediatr Blood Cancer. 2010 Apr; 54(4):654-6. PMID: 20146216.
    Citations: 1     Fields:    Translation:Humans
  67. Fangusaro J, Chi S. Introduction to a special issue on pediatric neuro-oncology. J Child Neurol. 2009 Nov; 24(11):1341-2. PMID: 19841423.
    Citations: 2     Fields:    Translation:Humans
  68. Manley P, Li X, Turner C, Chi S, Zimmerman MA, Chordas C, Gordon A, Baker A, Ullrich NJ, Goumnerova L, Marcus K, Hoffman K, Kieran MW. A prospective, blinded analysis of A-PROTEIN (recoverin or CAR protein) levels in pediatric patients with central nervous system tumors. Pediatr Blood Cancer. 2009 Sep; 53(3):343-7. PMID: 19422022.
    Citations: 1     Fields:    Translation:Humans
  69. Turner CD, Chordas CA, Liptak CC, Rey-Casserly C, Delaney BL, Ullrich NJ, Goumnerova LC, Scott RM, Begley HC, Fletcher WJ, Yao X, Chi S, Kieran MW. Medical, psychological, cognitive and educational late-effects in pediatric low-grade glioma survivors treated with surgery only. Pediatr Blood Cancer. 2009 Sep; 53(3):417-23. PMID: 19479971.
    Citations: 29     Fields:    Translation:Humans
  70. Jason Fangusaro and Susan N Chi, co-directors. Pediatric Neuro-Oncology: Back to the Basics. 2009.
  71. Mark W Kieran, Susan N Chi, David Samuel, Mirna Lechpammer, Samuel Blackman, Sanjay P Prabhu, Betsy Herrington, Christopher Turner, Karen J. Marcus and Roaslind Segal. Tumors of the Brain and Spinal Cord. Oncology of Infancy and Childhood (Orkin, Fisher, Look, Lux, Ginsbrug, Nathan, eds). 2009; 601-720.
  72. Chi SN, Zimmerman MA, Yao X, Cohen KJ, Burger P, Biegel JA, Rorke-Adams LB, Fisher MJ, Janss A, Mazewski C, Goldman S, Manley PE, Bowers DC, Bendel A, Rubin J, Turner CD, Marcus KJ, Goumnerova L, Ullrich NJ, Kieran MW. Intensive multimodality treatment for children with newly diagnosed CNS atypical teratoid rhabdoid tumor. J Clin Oncol. 2009 Jan 20; 27(3):385-9. PMID: 19064966.
    Citations: 131     Fields:    Translation:Humans
  73. Snuderl M, Chi SN, De Santis SM, Stemmer-Rachamimov AO, Betensky RA, De Girolami U, Kieran MW. Prognostic value of tumor microinvasion and metalloproteinases expression in intracranial pediatric ependymomas. J Neuropathol Exp Neurol. 2008 Sep; 67(9):911-20. PMID: 18716553.
    Citations: 10     Fields:    Translation:Humans
  74. Gilheeney SW, Saad A, Chi S, Turner C, Ullrich NJ, Goumnerova L, Scott RM, Marcus K, Lehman L, De Girolami U, Kieran MW. Outcome of pediatric pineoblastoma after surgery, radiation and chemotherapy. J Neurooncol. 2008 Aug; 89(1):89-95. PMID: 18415046.
    Citations: 15     Fields:    Translation:HumansPHPublic Health
  75. Susan N. Chi MD; William Fletcher; Xiaopan Yao PhD, Kenneth Cohen MD; Michael Fisher MD, Jacklyn Biegel PhD; Anna Janss MD; Stewart Goldman MD; Daniel Bowers MD; Peter Manley MD; Claire Mazewski MD; Anne Bendel MD; Joshua Rubin, MD PhD; Christopher D. Turner MD; Charles Roberts MD PhD; Karen Marcus MD; Liliana Goumnerova MD; Nicole Ullrich MD PhD; Christine Chordas PNP; Mary Ann Zimmerman PNP; Mark W. Kieran MD PhD. Results from a single-arm, multi-institutional Phase II study Of multi-agent intrathecal and systemic Cchemotherapy with age- and risk-adapted radiation therapy for children with newly diagnosed CNS Atypical Teratoid/Rhabdoid Tumor. Neuro-oncol. 2008; 10(3):373.
  76. Turner C, Begley H, Chordas C, Cieurzo C, Rey-Casserly C, Delaney B, Kim CUnningham L, Pomeroy S, Ullrich N, Goumnerova L, Scott RM, Marcus K, Fletcher W, Chi S, Kieran M. Long-term medical, psychologicak and educational isues in pediatric low-grade gliomas treated with surgery only. Neuro-Oncol. 2007.
  77. Zacharoulis S, Levy A, Chi SN, Gardner S, Rosenblum M, Miller DC, Dunkel I, Diez B, Sposto R, Ji L, Asgharzadeh S, Hukin J, Belasco J, Dubowy R, Kellie S, Termuhlen A, Finlay J. Outcome for young children newly diagnosed with ependymoma, treated with intensive induction chemotherapy followed by myeloablative chemotherapy and autologous stem cell rescue. Pediatr Blood Cancer. 2007 Jul; 49(1):34-40. PMID: 16874765.
    Citations: 35     Fields:    Translation:Humans
  78. Ullrich NJ, Robertson R, Kinnamon DD, Scott RM, Kieran MW, Turner CD, Chi SN, Goumnerova L, Proctor M, Tarbell NJ, Marcus KJ, Pomeroy SL. Moyamoya following cranial irradiation for primary brain tumors in children. Neurology. 2007 Mar 20; 68(12):932-8. PMID: 17372129.
    Citations: 69     Fields:    Translation:HumansPHPublic Health
  79. Gilheeney SW, Williams C, DeGirolami U, Chi S, Turner C, Ullrich N, Goumnerova L, Scott RM, Marcus K, Lehmann L and Kieran M. Pineoblastoma in the pediatric population: Review of a single institution’s experience. Neuro-Oncol. 2007; 9:201.
  80. Zimmerman MA, Turner C, Chi S, Chordas C, Scott RM, Goumnerova L, Proctor M, Marcus K, Pomeroy S, Ullrich N, Kieran . Glomerular filtration rate in comparison to serum creatinine and audiologic results in predicting toxicity in pediatric patients receiving vincristine and carboplatin. Neuro-Oncol. 2007; 9:175.
  81. Chi SN, Gardner S, Ji L, Sposto R, Dhall G, and Finlay JL. Newly diagnosed high-risk malignant brain tumors with leptomeningeal dissemination in young children: a final update on “Head Start” induction chemotherapy intensified with high-dose methotrexate. Proceedings of ASCO. 2007.
  82. Snuderl M M, Chi SN, Chan JA, Hladikova M, Rubin MA, Kieran MW and Ligon KL. Oligodendroglial lineage marker expression in ependymal tumors. Neuro-Oncol. 2007; 9:218.
  83. Chi SN, Snuderl M, DeGirolami U, Goumnerova L, Gordon A, Thomas A, Turner CD, Zimmerman MA, Chordas C, Ullrich N and Kieran MW. Does histologic grade correlate with clinical outcome in pediatric intracranial ependymoma?. Neuro-Oncol. 2007; 9:217.
  84. Fangusaro J, Gardner S, Abromowitch M, Allen J, Atlas M, Asgharzadeh S, Chi S, Comito M, Cornelius A, Diez B, Dubowy R, Garvin J, Halpern S, Hom B, Hukin J, Hurwitz C, Kellie S, Saly M, Termuhlen A, Zacharoulis S and Finla. Supratentorial primitive neuroectodermal tumors: Final outcome for children enrolled on Head Start I and II. Neuro-Oncol. 2007; 9:192.
  85. Turner CD, Chi S, Marcus KJ, MacDonald T, Packer RJ, Poussaint TY, Vajapeyam S, Ullrich N, Goumnerova LC, Scott RM, Briody C, Chordas C, Zimmerman MA, Kieran MW. Phase II study of thalidomide and radiation in children with newly diagnosed brain stem gliomas and glioblastoma multiforme. J Neurooncol. 2007 Mar; 82(1):95-101. PMID: 17031553.
    Citations: 22     Fields:    Translation:HumansCTClinical Trials
  86. Ullrich NJ, Marcus K, Pomeroy SL, Turner CD, Zimmerman M, Lehmann LE, Scott RM, Goumnerova L, Gillan E, Kieran MW, Chi SN. Transverse myelitis after therapy for primitive neuroectodermal tumors. Pediatr Neurol. 2006 Aug; 35(2):122-5. PMID: 16876009.
    Citations: 1     Fields:    Translation:Humans
  87. Kieran MW, Turner CD, Rubin JB, Chi SN, Zimmerman MA, Chordas C, Klement G, Laforme A, Gordon A, Thomas A, Neuberg D, Browder T, Folkman J. A feasibility trial of antiangiogenic (metronomic) chemotherapy in pediatric patients with recurrent or progressive cancer. J Pediatr Hematol Oncol. 2005 Nov; 27(11):573-81. PMID: 16282886.
    Citations: 57     Fields:    Translation:HumansCTClinical Trials
  88. Zimmerman MA, Goumnerova LC, Proctor M, Scott RM, Marcus K, Pomeroy SL, Turner CD, Chi SN, Chordas C, Kieran MW. Continuous remission of newly diagnosed and relapsed central nervous system atypical teratoid/rhabdoid tumor. J Neurooncol. 2005 Mar; 72(1):77-84. PMID: 15803379.
    Citations: 29     Fields:    Translation:Humans
  89. Chi SN, Gardner SL, Levy AS, Knopp EA, Miller DC, Wisoff JH, Weiner HL, Finlay JL. Feasibility and response to induction chemotherapy intensified with high-dose methotrexate for young children with newly diagnosed high-risk disseminated medulloblastoma. J Clin Oncol. 2004 Dec 15; 22(24):4881-7. PMID: 15611503.
    Citations: 53     Fields:    Translation:HumansCTClinical Trials
  90. Chi SN, Conklin LS, Qin J, Meyers PA, Huvos AG, Healey JH, Gorlick R. The patterns of relapse in osteosarcoma: the Memorial Sloan-Kettering experience. Pediatr Blood Cancer. 2004 Jan; 42(1):46-51. PMID: 14752794.
    Citations: 18     Fields:    Translation:Humans
  91. Chi S. Pediatric Neuro-Oncology Program Fellows Manual. 2004.
  92. Chi SN, Cheung NK, Cheung IY. Expression of SSX-2 and SSX-4 genes in neuroblastoma. Int J Biol Markers. 2002 Oct-Dec; 17(4):219-23. PMID: 12521124.
    Citations: 5     Fields:    Translation:Humans
  93. Mora J, Cheung NK, Juan G, Illei P, Cheung I, Akram M, Chi S, Ladanyi M, Cordon-Cardo C, Gerald WL. Neuroblastic and Schwannian stromal cells of neuroblastoma are derived from a tumoral progenitor cell. Cancer Res. 2001 Sep 15; 61(18):6892-8. PMID: 11559566.
    Citations: 32     Fields:    Translation:HumansCells
  94. Cheung IY, Chi SN, Cheung NK. Prognostic significance of GAGE detection in bone marrows on survival of patients with metastatic neuroblastoma. Med Pediatr Oncol. 2000 Dec; 35(6):632-4. PMID: 11107134.
    Citations: 5     Fields:    Translation:Humans
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.