Harvard Catalyst Profiles

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Zhongcong Xie, Ph.D., M.D.

Co-Author

This page shows the publications co-authored by Zhongcong Xie and Rudolph Tanzi.
Connection Strength

5.255
  1. RNAi-mediated knock-down of Dab and Numb attenuate Aß levels via ?-secretase mediated APP processing. Transl Neurodegener. 2012 Mar 22; 1(1):8.
    View in: PubMed
    Score: 0.497
  2. The common inhalation anesthetic isoflurane induces caspase activation and increases amyloid beta-protein level in vivo. Ann Neurol. 2008 Dec; 64(6):618-27.
    View in: PubMed
    Score: 0.395
  3. RNA interference silencing of the adaptor molecules ShcC and Fe65 differentially affect amyloid precursor protein processing and Abeta generation. J Biol Chem. 2007 Feb 16; 282(7):4318-4325.
    View in: PubMed
    Score: 0.345
  4. Isoflurane-induced apoptosis: a potential pathogenic link between delirium and dementia. J Gerontol A Biol Sci Med Sci. 2006 Dec; 61(12):1300-6.
    View in: PubMed
    Score: 0.344
  5. The common inhalation anesthetic isoflurane induces apoptosis and increases amyloid beta protein levels. Anesthesiology. 2006 May; 104(5):988-94.
    View in: PubMed
    Score: 0.330
  6. Alzheimer's disease and post-operative cognitive dysfunction. Exp Gerontol. 2006 Apr; 41(4):346-59.
    View in: PubMed
    Score: 0.328
  7. RNA interference-mediated silencing of X11alpha and X11beta attenuates amyloid beta-protein levels via differential effects on beta-amyloid precursor protein processing. J Biol Chem. 2005 Apr 15; 280(15):15413-21.
    View in: PubMed
    Score: 0.303
  8. Effects of RNAi-mediated silencing of PEN-2, APH-1a, and nicastrin on wild-type vs FAD mutant forms of presenilin 1. J Mol Neurosci. 2005; 25(1):67-77.
    View in: PubMed
    Score: 0.301
  9. Effects of RNA interference-mediated silencing of gamma-secretase complex components on cell sensitivity to caspase-3 activation. J Biol Chem. 2004 Aug 13; 279(33):34130-7.
    View in: PubMed
    Score: 0.290
  10. Hypocapnia induces caspase-3 activation and increases Abeta production. Neurodegener Dis. 2004; 1(1):29-37.
    View in: PubMed
    Score: 0.281
  11. The anesthetic sevoflurane induces tau trafficking from neurons to microglia. Commun Biol. 2021 05 12; 4(1):560.
    View in: PubMed
    Score: 0.234
  12. Peripheral surgical wounding and age-dependent neuroinflammation in mice. PLoS One. 2014; 9(5):e96752.
    View in: PubMed
    Score: 0.144
  13. Age-dependent postoperative cognitive impairment and Alzheimer-related neuropathology in mice. Sci Rep. 2014 Jan 20; 4:3766.
    View in: PubMed
    Score: 0.141
  14. Cerebrospinal fluid aß to tau ratio and postoperative cognitive change. Ann Surg. 2013 Aug; 258(2):364-9.
    View in: PubMed
    Score: 0.136
  15. Anesthetics isoflurane and desflurane differently affect mitochondrial function, learning, and memory. Ann Neurol. 2012 May; 71(5):687-98.
    View in: PubMed
    Score: 0.124
  16. The effects of isoflurane and desflurane on cognitive function in humans. Anesth Analg. 2012 Feb; 114(2):410-5.
    View in: PubMed
    Score: 0.121
  17. Anesthetic propofol attenuates the isoflurane-induced caspase-3 activation and Aß oligomerization. PLoS One. 2011; 6(11):e27019.
    View in: PubMed
    Score: 0.121
  18. The inhalation anesthetic isoflurane increases levels of proinflammatory TNF-a, IL-6, and IL-1ß. Neurobiol Aging. 2012 Jul; 33(7):1364-78.
    View in: PubMed
    Score: 0.114
  19. Amyloid-ß production via cleavage of amyloid-ß protein precursor is modulated by cell density. J Alzheimers Dis. 2010; 22(2):683-984.
    View in: PubMed
    Score: 0.106
  20. The common inhalational anesthetic sevoflurane induces apoptosis and increases beta-amyloid protein levels. Arch Neurol. 2009 May; 66(5):620-31.
    View in: PubMed
    Score: 0.102
  21. Isoflurane-induced caspase-3 activation is dependent on cytosolic calcium and can be attenuated by memantine. J Neurosci. 2008 Apr 23; 28(17):4551-60.
    View in: PubMed
    Score: 0.095
  22. The inhalation anesthetic desflurane induces caspase activation and increases amyloid beta-protein levels under hypoxic conditions. J Biol Chem. 2008 May 02; 283(18):11866-75.
    View in: PubMed
    Score: 0.094
  23. Isolation and characterization of the Drosophila ubiquilin ortholog dUbqln: in vivo interaction with early-onset Alzheimer disease genes. Hum Mol Genet. 2007 Nov 01; 16(21):2626-39.
    View in: PubMed
    Score: 0.090
  24. Ubiquilin 1 modulates amyloid precursor protein trafficking and Abeta secretion. J Biol Chem. 2006 Oct 27; 281(43):32240-53.
    View in: PubMed
    Score: 0.084
  25. Artefactual effects of lipid-based cell transfection reagents on AbetaPP processing and Abeta production. Amyloid. 2006 Jun; 13(2):86-92.
    View in: PubMed
    Score: 0.083
  26. Isoflurane decreases self-renewal capacity of rat cultured neural stem cells. Anesthesiology. 2011 Oct; 115(4):754-63.
    View in: PubMed
    Score: 0.030
  27. Altered hippocampal gene expression 2 days after general anesthesia in rats. Eur J Pharmacol. 2006 Nov 07; 549(1-3):71-8.
    View in: PubMed
    Score: 0.021
Connection Strength
The connection strength for co-authors is the sum of the scores for each of their shared publications.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.
Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.