Harvard Catalyst Profiles

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Olivier Nicolas Kocher, Ph.D., M.D.


The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. R01HL077780 (KOCHER, OLIVIER N.) Jul 1, 2004 - Dec 31, 2017
    Role of PDZK1 in lipid metabolism and atherosclerosis
    Role: Principal Investigator

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Brophy ML, Dong Y, Tao H, Yancey PG, Song K, Zhang K, Wen A, Wu H, Lee Y, Malovichko MV, Sithu SD, Wong S, Yu L, Kocher O, Bischoff J, Srivastava S, Linton MF, Ley K, Chen H. Myeloid-Specific Deletion of Epsins 1 and 2 Reduces Atherosclerosis by Preventing LRP-1 Downregulation. Circ Res. 2019 02 15; 124(4):e6-e19. PMID: 30595089.
    Citations: 7     Fields:    Translation:HumansAnimalsCells
  2. Ali A, Levantini E, Teo JT, Goggi J, Clohessy JG, Wu CS, Chen L, Yang H, Krishnan I, Kocher O, Zhang J, Soo RA, Bhakoo K, Chin TM, Tenen DG. Fatty acid synthase mediates EGFR palmitoylation in EGFR mutated non-small cell lung cancer. EMBO Mol Med. 2018 03; 10(3). PMID: 29449326.
    Citations: 19     Fields:    Translation:AnimalsCells
  3. Nishino M, Ashiku SK, Kocher ON, Thurer RL, Boiselle PM, Hatabu H. The Thymus: A Comprehensive Review-Erratum. Radiographics. 2017 May-Jun; 37(3):1004. PMID: 28493794.
    Citations: 5     Fields:    
  4. Pal R, Ke Q, Pihan GA, Yesilaltay A, Penman ML, Wang L, Chitraju C, Kang PM, Krieger M, Kocher O. Carboxy-terminal deletion of the HDL receptor reduces receptor levels in liver and steroidogenic tissues, induces hypercholesterolemia, and causes fatal heart disease. . 2016 12 01; 311(6):H1392-H1408. PMID: 27694217.
    Citations: 2     Translation:AnimalsCells
  5. Yong KJ, Basseres DS, Welner RS, Zhang WC, Yang H, Yan B, Alberich-Jorda M, Zhang J, de Figueiredo-Pontes LL, Battelli C, Hetherington CJ, Ye M, Zhang H, Maroni G, O'Brien K, Magli MC, Borczuk AC, Varticovski L, Kocher O, Zhang P, Moon YC, Sydorenko N, Cao L, Davis TW, Thakkar BM, Soo RA, Iwama A, Lim B, Halmos B, Neuberg D, Tenen DG, Levantini E. Targeted BMI1 inhibition impairs tumor growth in lung adenocarcinomas with low CEBPa expression. Sci Transl Med. 2016 08 03; 8(350):350ra104. PMID: 27488898.
    Citations: 16     Fields:    Translation:HumansAnimals
  6. Tsukada H, Seward KP, Rafeq S, Kocher O, Ernst A. Experimental Pilot Study of a Novel Endobronchial Drug Delivery Catheter. J Bronchology Interv Pulmonol. 2015 Oct; 22(4):312-8. PMID: 26492604.
    Citations: 1     Fields:    Translation:Animals
  7. Vanderlaan PA, Yamaguchi N, Folch E, Boucher DH, Kent MS, Gangadharan SP, Majid A, Goldstein MA, Huberman MS, Kocher ON, Costa DB. Success and failure rates of tumor genotyping techniques in routine pathological samples with non-small-cell lung cancer. Lung Cancer. 2014 Apr; 84(1):39-44. PMID: 24513263.
    Citations: 43     Fields:    Translation:Humans
  8. Folch E, Yamaguchi N, VanderLaan PA, Kocher ON, Boucher DH, Goldstein MA, Huberman MS, Kent MS, Gangadharan SP, Costa DB, Majid A. Adequacy of lymph node transbronchial needle aspirates using convex probe endobronchial ultrasound for multiple tumor genotyping techniques in non-small-cell lung cancer. J Thorac Oncol. 2013 Nov; 8(11):1438-1444. PMID: 24128714.
    Citations: 16     Fields:    Translation:Humans
  9. Yamaguchi N, Vanderlaan PA, Folch E, Boucher DH, Canepa HM, Kent MS, Gangadharan SP, Majid A, Kocher ON, Goldstein MA, Huberman MS, Costa DB. Smoking status and self-reported race affect the frequency of clinically relevant oncogenic alterations in non-small-cell lung cancers at a United States-based academic medical practice. Lung Cancer. 2013 Oct; 82(1):31-7. PMID: 23932486.
    Citations: 23     Fields:    Translation:Humans
  10. Kaczmarek E, Bakker JP, Clarke DN, Csizmadia E, Kocher O, Veves A, Tecilazich F, O'Donnell CP, Ferran C, Malhotra A. Molecular biomarkers of vascular dysfunction in obstructive sleep apnea. PLoS One. 2013; 8(7):e70559. PMID: 23923005.
    Citations: 27     Fields:    Translation:HumansAnimalsCells
  11. Tsukamoto K, Buck L, Inman W, Griffith L, Kocher O, Krieger M. Challenges in using cultured primary rodent hepatocytes or cell lines to study hepatic HDL receptor SR-BI regulation by its cytoplasmic adaptor PDZK1. PLoS One. 2013; 8(7):e69725. PMID: 23936087.
    Citations: 4     Fields:    Translation:HumansAnimalsCells
  12. Tsukamoto K, Wales TE, Daniels K, Pal R, Sheng R, Cho W, Stafford W, Engen JR, Krieger M, Kocher O. Noncanonical role of the PDZ4 domain of the adaptor protein PDZK1 in the regulation of the hepatic high density lipoprotein receptor scavenger receptor class B, type I (SR-BI). J Biol Chem. 2013 Jul 05; 288(27):19845-60. PMID: 23720744.
    Citations: 7     Fields:    Translation:HumansAnimalsCells
  13. Birrane G, Mulvaney EP, Pal R, Kinsella BT, Kocher O. Molecular analysis of the prostacyclin receptor's interaction with the PDZ1 domain of its adaptor protein PDZK1. PLoS One. 2013; 8(2):e53819. PMID: 23457445.
    Citations: 2     Fields:    Translation:Cells
  14. Amabile G, Welner RS, Nombela-Arrieta C, D'Alise AM, Di Ruscio A, Ebralidze AK, Kraytsberg Y, Ye M, Kocher O, Neuberg DS, Khrapko K, Silberstein LE, Tenen DG. In vivo generation of transplantable human hematopoietic cells from induced pluripotent stem cells. Blood. 2013 Feb 21; 121(8):1255-64. PMID: 23212524.
    Citations: 89     Fields:    Translation:HumansAnimalsCells
  15. Kazerounian S, Gerald D, Huang M, Chin YR, Udayakumar D, Zheng N, O'Donnell RK, Perruzzi C, Mangiante L, Pourat J, Phung TL, Bravo-Nuevo A, Shechter S, McNamara S, Duhadaway JB, Kocher ON, Brown LF, Toker A, Prendergast GC, Benjamin LE. RhoB differentially controls Akt function in tumor cells and stromal endothelial cells during breast tumorigenesis. Cancer Res. 2013 Jan 01; 73(1):50-61. PMID: 23135917.
    Citations: 20     Fields:    Translation:HumansAnimalsCells
  16. Bhasin M, Huang Z, Pradhan-Nabzdyk L, Malek JY, LoGerfo PJ, Contreras M, Guthrie P, Csizmadia E, Andersen N, Kocher O, Ferran C, LoGerfo FW. Temporal network based analysis of cell specific vein graft transcriptome defines key pathways and hub genes in implantation injury. PLoS One. 2012; 7(6):e39123. PMID: 22720046.
    Citations: 16     Fields:    Translation:AnimalsCells
  17. Brill A, Yesilaltay A, De Meyer SF, Kisucka J, Fuchs TA, Kocher O, Krieger M, Wagner DD. Extrahepatic high-density lipoprotein receptor SR-BI and apoA-I protect against deep vein thrombosis in mice. Arterioscler Thromb Vasc Biol. 2012 Aug; 32(8):1841-7. PMID: 22652597.
    Citations: 19     Fields:    Translation:AnimalsCells
  18. Basseres DS, D'Alò F, Yeap BY, Löwenberg EC, Gonzalez DA, Yasuda H, Dayaram T, Kocher ON, Godleski JJ, Richards WG, Meyerson M, Kobayashi S, Tenen DG, Halmos B, Costa DB. Frequent downregulation of the transcription factor Foxa2 in lung cancer through epigenetic silencing. Lung Cancer. 2012 Jul; 77(1):31-7. PMID: 22341411.
    Citations: 16     Fields:    Translation:HumansCells
  19. Kocher O, Birrane G, Yesilaltay A, Shechter S, Pal R, Daniels K, Krieger M. Identification of the PDZ3 domain of the adaptor protein PDZK1 as a second, physiologically functional binding site for the C terminus of the high density lipoprotein receptor scavenger receptor class B type I. J Biol Chem. 2011 Jul 15; 286(28):25171-86. PMID: 21602281.
    Citations: 9     Fields:    Translation:AnimalsCells
  20. Shrikhande GV, Scali ST, da Silva CG, Damrauer SM, Csizmadia E, Putheti P, Matthey M, Arjoon R, Patel R, Siracuse JJ, Maccariello ER, Andersen ND, Monahan T, Peterson C, Essayagh S, Studer P, Guedes RP, Kocher O, Usheva A, Veves A, Kaczmarek E, Ferran C. O-glycosylation regulates ubiquitination and degradation of the anti-inflammatory protein A20 to accelerate atherosclerosis in diabetic ApoE-null mice. PLoS One. 2010 Dec 06; 5(12):e14240. PMID: 21151899.
    Citations: 31     Fields:    Translation:AnimalsCells
  21. Kocher O, Birrane G, Tsukamoto K, Fenske S, Yesilaltay A, Pal R, Daniels K, Ladias JA, Krieger M. In vitro and in vivo analysis of the binding of the C terminus of the HDL receptor scavenger receptor class B, type I (SR-BI), to the PDZ1 domain of its adaptor protein PDZK1. J Biol Chem. 2010 Nov 05; 285(45):34999-5010. PMID: 20739281.
    Citations: 10     Fields:    Translation:AnimalsCells
  22. O'Brien KB, Alberich-Jordà M, Yadav N, Kocher O, Diruscio A, Ebralidze A, Levantini E, Sng NJ, Bhasin M, Caron T, Kim D, Steidl U, Huang G, Halmos B, Rodig SJ, Bedford MT, Tenen DG, Kobayashi S. CARM1 is required for proper control of proliferation and differentiation of pulmonary epithelial cells. Development. 2010 Jul; 137(13):2147-56. PMID: 20530543.
    Citations: 29     Fields:    Translation:AnimalsCells
  23. Yesilaltay A, Daniels K, Pal R, Krieger M, Kocher O. Loss of PDZK1 causes coronary artery occlusion and myocardial infarction in Paigen diet-fed apolipoprotein E deficient mice. PLoS One. 2009 Dec 01; 4(12):e8103. PMID: 19956623.
    Citations: 15     Fields:    Translation:Animals
  24. Kocher O, Krieger M. Role of the adaptor protein PDZK1 in controlling the HDL receptor SR-BI. Curr Opin Lipidol. 2009 Jun; 20(3):236-41. PMID: 19421056.
    Citations: 39     Fields:    Translation:HumansAnimalsCells
  25. Cheng J, Ke Q, Jin Z, Wang H, Kocher O, Morgan JP, Zhang J, Crumpacker CS. Cytomegalovirus infection causes an increase of arterial blood pressure. PLoS Pathog. 2009 May; 5(5):e1000427. PMID: 19436702.
    Citations: 52     Fields:    Translation:HumansAnimalsCells
  26. Singh AK, Riederer B, Krabbenhöft A, Rausch B, Bonhagen J, Lehmann U, de Jonge HR, Donowitz M, Yun C, Weinman EJ, Kocher O, Hogema BM, Seidler U. Differential roles of NHERF1, NHERF2, and PDZK1 in regulating CFTR-mediated intestinal anion secretion in mice. J Clin Invest. 2009 Mar; 119(3):540-50. PMID: 19221439.
    Citations: 39     Fields:    Translation:AnimalsCells
  27. Fenske SA, Yesilaltay A, Pal R, Daniels K, Barker C, Quiñones V, Rigotti A, Krieger M, Kocher O. Normal hepatic cell surface localization of the high density lipoprotein receptor, scavenger receptor class B, type I, depends on all four PDZ domains of PDZK1. J Biol Chem. 2009 Feb 27; 284(9):5797-806. PMID: 19116202.
    Citations: 19     Fields:    Translation:AnimalsCells
  28. Broere N, Chen M, Cinar A, Singh AK, Hillesheim J, Riederer B, Lünnemann M, Rottinghaus I, Krabbenhöft A, Engelhardt R, Rausch B, Weinman EJ, Donowitz M, Hubbard A, Kocher O, de Jonge HR, Hogema BM, Seidler U. Defective jejunal and colonic salt absorption and alteredNa(+)/H (+) exchanger 3 (NHE3) activity in NHE regulatory factor 1 (NHERF1) adaptor protein-deficient mice. Pflugers Arch. 2009 Mar; 457(5):1079-91. PMID: 18758809.
    Citations: 41     Fields:    Translation:AnimalsCells
  29. Fenske SA, Yesilaltay A, Pal R, Daniels K, Rigotti A, Krieger M, Kocher O. Overexpression of the PDZ1 domain of PDZK1 blocks the activity of hepatic scavenger receptor, class B, type I by altering its abundance and cellular localization. J Biol Chem. 2008 Aug 08; 283(32):22097-104. PMID: 18544532.
    Citations: 18     Fields:    Translation:AnimalsCells
  30. Kocher O, Yesilaltay A, Shen CH, Zhang S, Daniels K, Pal R, Chen J, Krieger M. Influence of PDZK1 on lipoprotein metabolism and atherosclerosis. Biochim Biophys Acta. 2008 May; 1782(5):310-6. PMID: 18342019.
    Citations: 21     Fields:    Translation:AnimalsCells
  31. Cinar A, Chen M, Riederer B, Bachmann O, Wiemann M, Manns M, Kocher O, Seidler U. NHE3 inhibition by cAMP and Ca2+ is abolished in PDZ-domain protein PDZK1-deficient murine enterocytes. J Physiol. 2007 Jun 15; 581(Pt 3):1235-46. PMID: 17395628.
    Citations: 35     Fields:    Translation:AnimalsCells
  32. Hillesheim J, Riederer B, Tuo B, Chen M, Manns M, Biber J, Yun C, Kocher O, Seidler U. Down regulation of small intestinal ion transport in PDZK1- (CAP70/NHERF3) deficient mice. Pflugers Arch. 2007 Jul; 454(4):575-86. PMID: 17347851.
    Citations: 28     Fields:    Translation:AnimalsCells
  33. Costa DB, Li S, Kocher O, Feins RH, Keller SM, Schiller JH, Johnson DH, Tenen DG, Halmos B. Immunohistochemical analysis of C/EBPalpha in non-small cell lung cancer reveals frequent down-regulation in stage II and IIIA tumors: a correlative study of E3590. Lung Cancer. 2007 Apr; 56(1):97-103. PMID: 17239984.
    Citations: 10     Fields:    Translation:HumansCells
  34. Kocher O, Cirovic C, Malynn E, Rowland CM, Bare LA, Young BA, Henslee JG, Laffler TG, Huff JB, Kruskall MS, Wong G, Bauer KA. Obstetric complications in patients with hereditary thrombophilia identified using the LCx microparticle enzyme immunoassay: a controlled study of 5,000 patients. Am J Clin Pathol. 2007 Jan; 127(1):68-75. PMID: 17145624.
    Citations: 8     Fields:    Translation:Humans
  35. Kubo S, Levantini E, Kobayashi S, Kocher O, Halmos B, Tenen DG, Takahashi M. Three-dimensional magnetic resonance microscopy of pulmonary solitary tumors in transgenic mice. Magn Reson Med. 2006 Sep; 56(3):698-703. PMID: 16902979.
    Citations: 5     Fields:    Translation:Animals
  36. Yesilaltay A, Kocher O, Pal R, Leiva A, Quiñones V, Rigotti A, Krieger M. PDZK1 is required for maintaining hepatic scavenger receptor, class B, type I (SR-BI) steady state levels but not its surface localization or function. J Biol Chem. 2006 Sep 29; 281(39):28975-80. PMID: 16867981.
    Citations: 22     Fields:    Translation:AnimalsCells
  37. Costa DB, Stephenson P, Kocher O, Tenen DG, Feins RH, Keller SM, Schiller JH, Johnson DH, Halmos B. C/EBPa expression by immunohistochemistry lacks prognostic or predictive significance in primary resected non-small cell lung cancer. J Clin Oncol. 2006 Jun 20; 24(18_suppl):7202. PMID: 27954067.
  38. Nishino M, Ashiku SK, Kocher ON, Thurer RL, Boiselle PM, Hatabu H. The thymus: a comprehensive review. Radiographics. 2006 Mar-Apr; 26(2):335-48. PMID: 16549602.
    Citations: 47     Fields:    Translation:Humans
  39. Cho D, Kocher O, Parker JA, Halmos B. Multiple positron-emission tomography false positives in a patient with malignant melanoma. Clin Oncol (R Coll Radiol). 2006 Feb; 18(1):87-8. PMID: 16477930.
    Citations:    Fields:    Translation:Humans
  40. Bassères DS, Levantini E, Ji H, Monti S, Elf S, Dayaram T, Fenyus M, Kocher O, Golub T, Wong KK, Halmos B, Tenen DG. Respiratory failure due to differentiation arrest and expansion of alveolar cells following lung-specific loss of the transcription factor C/EBPalpha in mice. Mol Cell Biol. 2006 Feb; 26(3):1109-23. PMID: 16428462.
    Citations: 32     Fields:    Translation:Animals
  41. Thomson RB, Wang T, Thomson BR, Tarrats L, Girardi A, Mentone S, Soleimani M, Kocher O, Aronson PS. Role of PDZK1 in membrane expression of renal brush border ion exchangers. Proc Natl Acad Sci U S A. 2005 Sep 13; 102(37):13331-6. PMID: 16141316.
    Citations: 24     Fields:    Translation:AnimalsCells
  42. Yesilaltay A, Kocher O, Rigotti A, Krieger M. Regulation of SR-BI-mediated high-density lipoprotein metabolism by the tissue-specific adaptor protein PDZK1. Curr Opin Lipidol. 2005 Apr; 16(2):147-52. PMID: 15767854.
    Citations: 18     Fields:    Translation:AnimalsCells
  43. Kobayashi S, Boggon TJ, Dayaram T, Jänne PA, Kocher O, Meyerson M, Johnson BE, Eck MJ, Tenen DG, Halmos B. EGFR mutation and resistance of non-small-cell lung cancer to gefitinib. N Engl J Med. 2005 Feb 24; 352(8):786-92. PMID: 15728811.
    Citations: 1296     Fields:    Translation:HumansCells
  44. Mayer S, Cypess AM, Kocher ON, Berman SM, Huberman MS, Hartzband PI, Halmos B. Uncommon presentations of some common malignancies: Case 1. Sequential paraneoplastic endocrine syndromes in small-cell lung cancer. J Clin Oncol. 2005 Feb 20; 23(6):1312-4. PMID: 15718329.
    Citations: 8     Fields:    Translation:Humans
  45. Cho D, Kocher O, Lee JC, Tenen DG, Meyerson ML, Janne PA, Halmos B. Unusual cases in multiple myeloma and a dramatic response in metastatic lung cancer: case 4. Mutation of the epidermal growth factor receptor in an elderly man with advanced, gefitinib-responsive, non-small-cell lung cancer. J Clin Oncol. 2005 Jan 01; 23(1):235-7. PMID: 15625379.
    Citations: 2     Fields:    Translation:Humans
  46. Djalilvand A, Pal R, Goldman H, Antonioli D, Kocher O. Evaluation of p53 mutations in premalignant esophageal lesions and esophageal adenocarcinoma using laser capture microdissection. Mod Pathol. 2004 Nov; 17(11):1323-7. PMID: 15257314.
    Citations: 1     Fields:    Translation:HumansCells
  47. Capuano P, Bacic D, Stange G, Hernando N, Kaissling B, Pal R, Kocher O, Biber J, Wagner CA, Murer H. Expression and regulation of the renal Na/phosphate cotransporter NaPi-IIa in a mouse model deficient for the PDZ protein PDZK1. Pflugers Arch. 2005 Jan; 449(4):392-402. PMID: 15517343.
    Citations: 25     Fields:    Translation:AnimalsCells
  48. Chen Y, Sharp PM, Fowkes M, Kocher O, Joseph JT, Koralnik IJ. Analysis of 15 novel full-length BK virus sequences from three individuals: evidence of a high intra-strain genetic diversity. J Gen Virol. 2004 Sep; 85(Pt 9):2651-2663. PMID: 15302959.
    Citations: 22     Fields:    Translation:HumansCells
  49. Pantanowitz L, Bauer K, Tefs K, Schuster V, Balogh K, Pilch BZ, Adcock D, Cirovic C, Kocher O. Ligneous (pseudomembranous) inflammation involving the female genital tract associated with type-1 plasminogen deficiency. Int J Gynecol Pathol. 2004 Jul; 23(3):292-5. PMID: 15213608.
    Citations: 5     Fields:    Translation:Humans
  50. Kocher O, Yesilaltay A, Cirovic C, Pal R, Rigotti A, Krieger M. Targeted disruption of the PDZK1 gene in mice causes tissue-specific depletion of the high density lipoprotein receptor scavenger receptor class B type I and altered lipoprotein metabolism. J Biol Chem. 2003 Dec 26; 278(52):52820-5. PMID: 14551195.
    Citations: 63     Fields:    Translation:AnimalsCells
  51. Sussman LK, Upalakalin JN, Roberts MJ, Kocher O, Benjamin LE. Blood markers for vasculogenesis increase with tumor progression in patients with breast carcinoma. . 2003 May-Jun; 2(3):255-6. PMID: 12878859.
    Citations: 9     Translation:Humans
  52. Kocher O, Pal R, Roberts M, Cirovic C, Gilchrist A. Targeted disruption of the PDZK1 gene by homologous recombination. Mol Cell Biol. 2003 Feb; 23(4):1175-80. PMID: 12556478.
    Citations: 40     Fields:    Translation:AnimalsCells
  53. Halmos B, Huettner CS, Kocher O, Ferenczi K, Karp DD, Tenen DG. Down-regulation and antiproliferative role of C/EBPalpha in lung cancer. Cancer Res. 2002 Jan 15; 62(2):528-34. PMID: 11809705.
    Citations: 48     Fields:    Translation:HumansCells
  54. Gilchrist A, Solomon N, Erickson D, Sikand A, Bauer KA, Kruskall MS, Kocher O. Automated detection of the G20210A prothrombin mutation using the LCx microparticle enzyme immunoassay. Clin Chim Acta. 2001 Dec; 314(1-2):249-54. PMID: 11718704.
    Citations: 1     Fields:    Translation:HumansCTClinical Trials
  55. Kadin ME, Drews R, Samel A, Gilchrist A, Kocher O. Hodgkin's lymphoma of T-cell type: clonal association with a CD30+ cutaneous lymphoma. Hum Pathol. 2001 Nov; 32(11):1269-72. PMID: 11727269.
    Citations: 3     Fields:    Translation:HumansCells
  56. Vasile E, Tomita Y, Brown LF, Kocher O, Dvorak HF. Differential expression of thymosin beta-10 by early passage and senescent vascular endothelium is modulated by VPF/VEGF: evidence for senescent endothelial cells in vivo at sites of atherosclerosis. FASEB J. 2001 Feb; 15(2):458-66. PMID: 11156961.
    Citations: 55     Fields:    Translation:HumansCells
  57. Fu Y, Comella N, Tognazzi K, Brown LF, Dvorak HF, Kocher O. Cloning of DLM-1, a novel gene that is up-regulated in activated macrophages, using RNA differential display. Gene. 1999 Nov 15; 240(1):157-63. PMID: 10564822.
    Citations: 40     Fields:    Translation:HumansAnimalsCells
  58. Kocher O, Comella N, Gilchrist A, Pal R, Tognazzi K, Brown LF, Knoll JH. PDZK1, a novel PDZ domain-containing protein up-regulated in carcinomas and mapped to chromosome 1q21, interacts with cMOAT (MRP2), the multidrug resistance-associated protein. Lab Invest. 1999 Sep; 79(9):1161-70. PMID: 10496535.
    Citations: 34     Fields:    Translation:HumansCells
  59. Kim E, Arnould T, Sellin L, Benzing T, Comella N, Kocher O, Tsiokas L, Sukhatme VP, Walz G. Interaction between RGS7 and polycystin. Proc Natl Acad Sci U S A. 1999 May 25; 96(11):6371-6. PMID: 10339594.
    Citations: 31     Fields:    Translation:HumansAnimalsCells
  60. Abu-Jawdeh G, Comella N, Tomita Y, Brown LF, Tognazzi K, Sokol SY, Kocher O. Differential expression of frpHE: a novel human stromal protein of the secreted frizzled gene family, during the endometrial cycle and malignancy. Lab Invest. 1999 Apr; 79(4):439-47. PMID: 10211996.
    Citations: 14     Fields:    Translation:HumansAnimalsCells
  61. Lee SW, Reimer CL, Campbell DB, Cheresh P, Duda RB, Kocher O. H-cadherin expression inhibits in vitro invasiveness and tumor formation in vivo. Carcinogenesis. 1998 Jun; 19(6):1157-9. PMID: 9667758.
    Citations: 14     Fields:    Translation:HumansAnimalsCells
  62. Wechsler ME, Garpestad E, Flier SR, Kocher O, Weiland DA, Polito AJ, Klinek MM, Bigby TD, Wong GA, Helmers RA, Drazen JM. Pulmonary infiltrates, eosinophilia, and cardiomyopathy following corticosteroid withdrawal in patients with asthma receiving zafirlukast. JAMA. 1998 Feb 11; 279(6):455-7. PMID: 9466639.
    Citations: 35     Fields:    Translation:Humans
  63. Kocher O, Comella N, Tognazzi K, Brown LF. Identification and partial characterization of PDZK1: a novel protein containing PDZ interaction domains. Lab Invest. 1998 Jan; 78(1):117-25. PMID: 9461128.
    Citations: 50     Fields:    Translation:HumansCells
  64. Park KW, Dai HB, Lowenstein E, Kocher ON, Sellke FW. Isoflurane- and halothane-mediated dilation of distal bronchi in the rat depends on the epithelium. Anesthesiology. 1997 May; 86(5):1078-87; discussion 23A-24A. PMID: 9158357.
    Citations:    Fields:    Translation:Animals
  65. Kocher O, Cheresh P, Lee SW. Identification and partial characterization of a novel membrane-associated protein (MAP17) up-regulated in human carcinomas and modulating cell replication and tumor growth. Am J Pathol. 1996 Aug; 149(2):493-500. PMID: 8701988.
    Citations: 18     Fields:    Translation:HumansAnimalsCells
  66. Kocher O, Cheresh P, Brown LF, Lee SW. Identification of a novel gene, selectively up-regulated in human carcinomas, using the differential display technique. Clin Cancer Res. 1995 Oct; 1(10):1209-15. PMID: 9815914.
    Citations: 13     Fields:    Translation:HumansCells
  67. Detmar M, Brown LF, Claffey KP, Yeo KT, Kocher O, Jackman RW, Berse B, Dvorak HF. Overexpression of vascular permeability factor/vascular endothelial growth factor and its receptors in psoriasis. J Exp Med. 1994 Sep 01; 180(3):1141-6. PMID: 8064230.
    Citations: 134     Fields:    Translation:HumansCells
  68. Basson CT, Kocher O, Basson MD, Asis A, Madri JA. Differential modulation of vascular cell integrin and extracellular matrix expression in vitro by TGF-beta 1 correlates with reciprocal effects on cell migration. J Cell Physiol. 1992 Oct; 153(1):118-28. PMID: 1522126.
    Citations: 27     Fields:    Translation:AnimalsCells
  69. Kocher O, Gabbiani F, Gabbiani G, Reidy MA, Cokay MS, Peters H, Hüttner I. Phenotypic features of smooth muscle cells during the evolution of experimental carotid artery intimal thickening. Biochemical and morphologic studies. Lab Invest. 1991 Oct; 65(4):459-70. PMID: 1921335.
    Citations: 35     Fields:    Translation:Animals
  70. Amberger A, Bauer H, Tontsch U, Gabbiani G, Kocher O, Bauer HC. Reversible expression of sm alpha-actin protein and sm alpha-actin mRNA in cloned cerebral endothelial cells. FEBS Lett. 1991 Aug 05; 287(1-2):223-5. PMID: 1879532.
    Citations: 4     Fields:    Translation:AnimalsCells
  71. Kocher O, Kennedy SP, Madri JA. Alternative splicing of endothelial cell fibronectin mRNA in the IIICS region. Functional significance. Am J Pathol. 1990 Dec; 137(6):1509-24. PMID: 2260635.
    Citations: 15     Fields:    Translation:AnimalsCells
  72. Chaponnier C, Kocher O, Gabbiani G. Modulation of gelsolin content in rat aortic smooth muscle cells during development, experimental intimal thickening and culture. An immunohistochemical and biochemical study. Eur J Biochem. 1990 Jul 05; 190(3):559-65. PMID: 2164930.
    Citations: 5     Fields:    Translation:AnimalsCells
  73. Madri JA, Kocher O, Merwin JR, Bell L, Tucker A, Basson CT. Interactions of vascular cells with transforming growth factors-beta. Ann N Y Acad Sci. 1990; 593:243-58. PMID: 1695825.
    Citations: 5     Fields:    Translation:AnimalsCells
  74. Merwin JR, Anderson JM, Kocher O, Van Itallie CM, Madri JA. Transforming growth factor beta 1 modulates extracellular matrix organization and cell-cell junctional complex formation during in vitro angiogenesis. J Cell Physiol. 1990 Jan; 142(1):117-28. PMID: 1688859.
    Citations: 30     Fields:    Translation:AnimalsCells
  75. Campbell JH, Kocher O, Skalli O, Gabbiani G, Campbell GR. Cytodifferentiation and expression of alpha-smooth muscle actin mRNA and protein during primary culture of aortic smooth muscle cells. Correlation with cell density and proliferative state. Arteriosclerosis. 1989 Sep-Oct; 9(5):633-43. PMID: 2675809.
    Citations: 34     Fields:    Translation:AnimalsCells
  76. Madri JA, Reidy MA, Kocher O, Bell L. Endothelial cell behavior after denudation injury is modulated by transforming growth factor-beta1 and fibronectin. Lab Invest. 1989 Jun; 60(6):755-65. PMID: 2659888.
    Citations: 28     Fields:    Translation:AnimalsCells
  77. Kocher O, Madri JA. Modulation of actin mRNAs in cultured vascular cells by matrix components and TGF-beta 1. In Vitro Cell Dev Biol. 1989 May; 25(5):424-34. PMID: 2659578.
    Citations: 14     Fields:    Translation:AnimalsCells
  78. Madri JA, Kocher O, Merwin JR, Bell L, Yannariello-Brown J. The interactions of vascular cells with solid phase (matrix) and soluble factors. J Cardiovasc Pharmacol. 1989; 14 Suppl 6:S70-5. PMID: 2478828.
    Citations: 5     Fields:    Translation:HumansAnimals
  79. Clowes AW, Clowes MM, Kocher O, Ropraz P, Chaponnier C, Gabbiani G. Arterial smooth muscle cells in vivo: relationship between actin isoform expression and mitogenesis and their modulation by heparin. J Cell Biol. 1988 Nov; 107(5):1939-45. PMID: 2460473.
    Citations: 19     Fields:    Translation:Animals
  80. Hansson GK, Jonasson L, Lojsthed B, Stemme S, Kocher O, Gabbiani G. Localization of T lymphocytes and macrophages in fibrous and complicated human atherosclerotic plaques. Atherosclerosis. 1988 Aug; 72(2-3):135-41. PMID: 3063267.
    Citations: 36     Fields:    Translation:HumansCells
  81. Campbell JH, Campbell GR, Kocher O, Gabbiani G. Cell biology of smooth muscle in culture: implications for atherogenesis. Int Angiol. 1987 Jan-Mar; 6(1):73-9. PMID: 3624951.
    Citations:    Fields:    Translation:HumansAnimalsCells
  82. Kocher O, Gabbiani G. Analysis of alpha-smooth-muscle actin mRNA expression in rat aortic smooth-muscle cells using a specific cDNA probe. Differentiation. 1987; 34(3):201-9. PMID: 3428507.
    Citations: 19     Fields:    Translation:AnimalsCells
  83. Kocher O, Gabbiani G. Cytoskeletal features of normal and atheromatous human arterial smooth muscle cells. Hum Pathol. 1986 Sep; 17(9):875-80. PMID: 3759072.
    Citations: 30     Fields:    Translation:HumansCells
  84. Kocher O, Gabbiani G. Expression of actin mRNAs in rat aortic smooth muscle cells during development, experimental intimal thickening, and culture. Differentiation. 1986; 32(3):245-51. PMID: 3792709.
    Citations: 19     Fields:    Translation:AnimalsCells
  85. Kocher O, Skalli O, Cerutti D, Gabbiani F, Gabbiani G. Cytoskeletal features of rat aortic cells during development. An electron microscopic, immunohistochemical, and biochemical study. Circ Res. 1985 Jun; 56(6):829-38. PMID: 3891126.
    Citations: 27     Fields:    Translation:AnimalsCells
  86. Kocher O, Skalli O, Bloom WS, Gabbiani G. Cytoskeleton of rat aortic smooth muscle cells. Normal conditions and experimental intimal thickening. Lab Invest. 1984 Jun; 50(6):645-52. PMID: 6727297.
    Citations: 52     Fields:    Translation:Animals
  87. Targett RC, Kocher O, Muramatsu K, McIlroy MB. Skin gas tensions and resistances measured by mass spectrometry in adults. J Appl Physiol Respir Environ Exerc Physiol. 1984 May; 56(5):1431-5. PMID: 6427157.
    Citations:    Fields:    Translation:Humans
  88. Gabbiani G, Kocher O, Bloom WS, Vandekerckhove J, Weber K. Actin expression in smooth muscle cells of rat aortic intimal thickening, human atheromatous plaque, and cultured rat aortic media. J Clin Invest. 1984 Jan; 73(1):148-52. PMID: 6690475.
    Citations: 64     Fields:    Translation:HumansAnimals
  89. Gabbiani G, Kocher O. Cytocontractile and cytoskeletal elements in pathologic processes. Pathogenetic role and diagnostic value. Arch Pathol Lab Med. 1983 Dec; 107(12):622-5. PMID: 6357140.
    Citations: 1     Fields:    Translation:HumansCells
  90. Schindler AM, Amaudruz MA, Kocher O, Riotton G, Gabbiani G. Desmosomes and gap-junctions in various epidermoid preneoplastic and neoplastic lesions of the cervix uteri. Acta Cytol. 1982 Jul-Aug; 26(4):466-70. PMID: 6957099.
    Citations: 7     Fields:    Translation:HumansCells
  91. Montandon D, Kocher O, Gabbiani G. Cancer invasiveness: immunofluorescent and ultrastructural methods of assessment. Plast Reconstr Surg. 1982 Feb; 69(2):365-71. PMID: 7034017.
    Citations:    Fields:    Translation:HumansCells
  92. Kocher O, Amaudruz M, Schindler AM, Gabbiani G. Desmosomes and gap junctions in precarcinomatous and carcinomatous conditions of squamous epithelia. An electron microscopic and morphometrical study. J Submicrosc Cytol. 1981 Apr; 13(2):267-81. PMID: 7338968.
    Citations: 4     Fields:    Translation:HumansCells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.