Concepts
This page shows the publications Philip Larsen has written about Molecular Sequence Data.
Connection Strength
0.530
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Cellular and structural biology of the deiodinases. Thyroid. 2005 Aug; 15(8):777-86.
Score: 0.027
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The mRNA structure has potent regulatory effects on type 2 iodothyronine deiodinase expression. Mol Endocrinol. 2002 Jul; 16(7):1667-79.
Score: 0.022
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Biochemistry, cellular and molecular biology, and physiological roles of the iodothyronine selenodeiodinases. Endocr Rev. 2002 Feb; 23(1):38-89.
Score: 0.021
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The human, but not rat, dio2 gene is stimulated by thyroid transcription factor-1 (TTF-1). Mol Endocrinol. 2001 Jan; 15(1):112-24.
Score: 0.020
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Substrate-induced down-regulation of human type 2 deiodinase (hD2) is mediated through proteasomal degradation and requires interaction with the enzyme's active center. Endocrinology. 2000 Mar; 141(3):1127-35.
Score: 0.019
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Characterization of the 5'-flanking and 5'-untranslated regions of the cyclic adenosine 3',5'-monophosphate-responsive human type 2 iodothyronine deiodinase gene. Endocrinology. 2000 Jan; 141(1):229-37.
Score: 0.019
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Cloning and expression of the chicken type 2 iodothyronine 5'-deiodinase. J Biol Chem. 1999 May 14; 274(20):13768-76.
Score: 0.018
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The 3'-untranslated region of human type 2 iodothyronine deiodinase mRNA contains a functional selenocysteine insertion sequence element. J Biol Chem. 1998 Dec 11; 273(50):33374-8.
Score: 0.017
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The guanosine monophosphate reductase gene is conserved in rats and its expression increases rapidly in brown adipose tissue during cold exposure. J Biol Chem. 1998 Nov 20; 273(47):31092-6.
Score: 0.017
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Further characterization of thyroid hormone response elements in the human type 1 iodothyronine deiodinase gene. Endocrinology. 1998 Mar; 139(3):1156-63.
Score: 0.016
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The role of the active site cysteine in catalysis by type 1 iodothyronine deiodinase. Endocrinology. 1997 Dec; 138(12):5452-8.
Score: 0.016
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Update on the human iodothyronine selenodeiodinases, the enzymes regulating the activation and inactivation of thyroid hormone. Biochem Soc Trans. 1997 May; 25(2):588-92.
Score: 0.015
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Molecular biological and biochemical characterization of the human type 2 selenodeiodinase. Endocrinology. 1996 Aug; 137(8):3308-15.
Score: 0.015
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In vivo genomic footprinting of thyroid hormone-responsive genes in pituitary tumor cell lines. Mol Cell Biol. 1996 Aug; 16(8):4465-77.
Score: 0.015
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Structural features of thyroid hormone response elements that increase susceptibility to inhibition by an RTH mutant thyroid hormone receptor. Endocrinology. 1996 Jul; 137(7):2833-41.
Score: 0.015
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The structure of the coding and 5'-flanking region of the type 1 iodothyronine deiodinase (dio1) gene is normal in a patient with suspected congenital dio1 deficiency. J Clin Endocrinol Metab. 1996 Jun; 81(6):2121-4.
Score: 0.014
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Enhancement of thyroid hormone receptor isoform specificity by insertion of a distant half-site into a thyroid hormone response element. Endocrinology. 1996 Apr; 137(4):1438-46.
Score: 0.014
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Type 3 lodothyronine deiodinase: cloning, in vitro expression, and functional analysis of the placental selenoenzyme. J Clin Invest. 1995 Nov; 96(5):2421-30.
Score: 0.014
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A novel retinoid X receptor-independent thyroid hormone response element is present in the human type 1 deiodinase gene. Mol Cell Biol. 1995 Sep; 15(9):5100-12.
Score: 0.014
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Structural and functional differences in the dio1 gene in mice with inherited type 1 deiodinase deficiency. Mol Endocrinol. 1995 Aug; 9(8):969-80.
Score: 0.014
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Topological analysis of the integral membrane protein, type 1 iodothyronine deiodinase (D1). J Biol Chem. 1995 May 19; 270(20):12310-8.
Score: 0.013
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Nutritional and hormonal regulation of thyroid hormone deiodinases. Annu Rev Nutr. 1995; 15:323-52.
Score: 0.013
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Identification of critical amino acids for 3,5,3'-triiodothyronine deiodination by human type 1 deiodinase based on comparative functional-structural analyses of the human, dog, and rat enzymes. J Biol Chem. 1994 Aug 12; 269(32):20329-34.
Score: 0.013
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Type I iodothyronine deiodinase: unexpected complexities in a simple deiodination reaction. Thyroid. 1994; 4(3):357-62.
Score: 0.012
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Recognition of UGA as a selenocysteine codon in eukaryotes: a review of recent progress. Biochem Soc Trans. 1993 Nov; 21(4):827-32.
Score: 0.012
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Dominant negative inhibition by mutant thyroid hormone receptors is thyroid hormone response element and receptor isoform specific. Mol Endocrinol. 1993 Oct; 7(10):1319-30.
Score: 0.012
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Functional characterization of the eukaryotic SECIS elements which direct selenocysteine insertion at UGA codons. EMBO J. 1993 Aug; 12(8):3315-22.
Score: 0.012
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Cloning and in vitro expression of the human selenoprotein, type I iodothyronine deiodinase. J Clin Endocrinol Metab. 1992 Oct; 75(4):1133-9.
Score: 0.011
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Capacity for cooperative binding of thyroid hormone (T3) receptor dimers defines wild type T3 response elements. Mol Endocrinol. 1992 Apr; 6(4):502-14.
Score: 0.011
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Recognition of UGA as a selenocysteine codon in type I deiodinase requires sequences in the 3' untranslated region. Nature. 1991 Sep 19; 353(6341):273-6.
Score: 0.010
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Effects of varying the position of thyroid hormone response elements within the rat growth hormone promoter: implications for positive and negative regulation by 3,5,3'-triiodothyronine. Mol Endocrinol. 1991 Apr; 5(4):542-8.
Score: 0.010
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Type I iodothyronine deiodinase is a selenocysteine-containing enzyme. Nature. 1991 Jan 31; 349(6308):438-40.
Score: 0.010
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Mutations of the rat growth hormone promoter which increase and decrease response to thyroid hormone define a consensus thyroid hormone response element. Mol Endocrinol. 1989 Dec; 3(12):1996-2004.
Score: 0.009
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The thyroid hormone-inactivating deiodinase functions as a homodimer. Mol Endocrinol. 2008 Jun; 22(6):1382-93.
Score: 0.008
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The iodothyronine selenodeiodinases are thioredoxin-fold family proteins containing a glycoside hydrolase clan GH-A-like structure. J Biol Chem. 2003 Sep 19; 278(38):36887-96.
Score: 0.006
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Selective proteolysis of human type 2 deiodinase: a novel ubiquitin-proteasomal mediated mechanism for regulation of hormone activation. Mol Endocrinol. 2000 Nov; 14(11):1697-708.
Score: 0.005
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Structure-activity relationships for thyroid hormone deiodination by mammalian type I iodothyronine deiodinases. Endocrinology. 1997 Jan; 138(1):213-9.
Score: 0.004
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Characterization of the promoter of the rat sarcoplasmic endoplasmic reticulum Ca2+-ATPase 1 gene and analysis of thyroid hormone responsiveness. J Biol Chem. 1996 Dec 13; 271(50):32048-56.
Score: 0.004
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Differential capacity of wild type promoter elements for binding and trans-activation by retinoic acid and thyroid hormone receptors. Mol Endocrinol. 1992 Oct; 6(10):1527-37.
Score: 0.003
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Thyroid hormone aporeceptor represses T3-inducible promoters and blocks activity of the retinoic acid receptor. New Biol. 1989 Dec; 1(3):329-36.
Score: 0.002
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Identification of a thyroid hormone receptor that is pituitary-specific. Science. 1989 Apr 07; 244(4900):76-9.
Score: 0.002
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Functional characterization of the rat growth hormone promoter elements required for induction by thyroid hormone with and without a co-transfected beta type thyroid hormone receptor. J Biol Chem. 1989 Jan 05; 264(1):178-82.
Score: 0.002
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Isolation of a cDNA clone encoding a biologically active thyroid hormone receptor. Proc Natl Acad Sci U S A. 1988 Jul; 85(14):5031-5.
Score: 0.002
Connection Strength
The connection strength for concepts is the sum of the scores for each matching publication.
Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.