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profileJoseph Frank Merola, M.D.

TitleAssistant Professor of Dermatology
InstitutionBrigham and Women's Hospital
DepartmentDermatology
AddressBrigham and Women's Hospital
Rheumatology
75 Francis St
Boston MA 02115
Phone6172645943
Fax6172643021
vCardDownload vCard (login for email)

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Clinically trained in internal medicine (board certified - ABIM), dermatology (board certified- ABD) and rheumatology (active fellow); interest in rhematology-dermatology overlap diseases (lupus, dermatomyositis, scleroderma, psoriasis/psoriatic arthritis, vasculitis).
Clinical translational research interest in autoimmunity broadly and in the diseases listed above; current MMSc student in the Harvard Clinical Scholars Program.


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Collapse selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Thorlacius L, Garg A, Ingram JR, Villumsen B, Theut Riis P, Gottlieb AB, Merola JF, Dellavalle R, Ardon C, Baba R, Bechara FG, Cohen AD, Daham N, Davis M, Emtestam L, Fernandez-Penas P, Filippelli M, Gibbons A, Grant T, Guilbault S, Gulliver S, Harris C, Harvent C, Houston K, Kirby JS, Matusiak L, Mehdizadeh A, Mojica T, Okun M, Orgill D, Pallack L, Parks-Miller A, Prens EP, Randell S, Rogers C, Rosen CF, Choon SE, van der Zee HH, Christensen R, Jemec GBE. Towards global consensus on core outcomes for Hidradenitis Suppurativa research: An update from the HISTORIC consensus meetings I and II. Br J Dermatol. 2017 Oct 28. PMID: 29080368.
    View in: PubMed
  2. Mease P, Hall S, FitzGerald O, van der Heijde D, Merola JF, Avila-Zapata F, Cieslak D, Graham D, Wang C, Menon S, Hendrikx T, Kanik KS. Tofacitinib or Adalimumab versus Placebo for Psoriatic Arthritis. N Engl J Med. 2017 10 19; 377(16):1537-1550. PMID: 29045212.
    View in: PubMed
  3. Gunasekera NS, Maniar LEG, Lezcano C, Laga AC, Merola JF. Intralesional Sodium Thiosulfate Treatment for Calcinosis Cutis in the Setting of Lupus Panniculitis. JAMA Dermatol. 2017 Sep 01; 153(9):944-945. PMID: 28564698.
    View in: PubMed
  4. Fruchter R, Kurtzman DJB, Patel M, Merola J, Franks AG, Vleugels RA, Femia AN. Characteristics and Alternative Treatment Outcomes of Antimalarial-Refractory Cutaneous Lupus Erythematosus. JAMA Dermatol. 2017 Sep 01; 153(9):937-939. PMID: 28636714.
    View in: PubMed
  5. Schneeweiss M, Merola JF, Karlson EW, Solomon DH. Rationale and Design of the Brigham Cohort for psoriasis and psoriatic arthritis registry (COPPAR). BMC Dermatol. 2017 Aug 16; 17(1):11. PMID: 28814312.
    View in: PubMed
  6. Lee MP, Lii J, Jin Y, Desai RJ, Solomon DH, Merola JF, Kim SC. Patterns of Systemic Treatment for Psoriatic Arthritis in the United States: 2004-2015. Arthritis Care Res (Hoboken). 2017 Aug 13. PMID: 28804988.
    View in: PubMed
  7. Perez-Chada LM, Singh S, Callis-Duffin K, Garg A, Gottlieb AB, Latella J, Armstrong AW, Merola JF. International Dermatology Outcome Measures (IDEOM) Group 2016 New York Meeting: Meeting Summary and Data from the Psoriasis Working Group. J Drugs Dermatol. 2017 Aug 01; 16(8):770-777. PMID: 28809992.
    View in: PubMed
  8. Merola JF, Bleakman AP, Gottlieb AB, Menter A, Naegeli AN, Bissonnette R, Guenther L, Sullivan J, Meeuwis K, See K, Duffin KC. The Static Physician's Global Assessment of Genitalia: A Clinical Outcome Measure for the Severity of Genital Psoriasis. J Drugs Dermatol. 2017 Aug 01; 16(8):793-799. PMID: 28809994.
    View in: PubMed
  9. Khosravi H, Siegel MP, Van Voorhees AS, Merola JF. Treatment of Inverse/Intertriginous Psoriasis: Updated Guidelines from the Medical Board of the National Psoriasis Foundation. J Drugs Dermatol. 2017 Aug 01; 16(8):760-766. PMID: 28809991.
    View in: PubMed
  10. Song P, Fett NM, Lin J, Merola JF, Costner M, Vleugels RA. Lack of Response to Intravenous Sodium Thiosulfate in Three Cases of Extensive Connective Tissue Disease-Associated Calcinosis Cutis. Br J Dermatol. 2017 Jul 01. PMID: 28667747.
    View in: PubMed
  11. Elman SA, Joyce C, Nyberg F, Furukawa F, Goodfield M, Hasegawa M, Marinovic B, Szepietowski JC, Dutz J, Werth VP, Merola JF. Development of classification criteria for discoid lupus erythematosus: Results of a Delphi exercise. J Am Acad Dermatol. 2017 Aug; 77(2):261-267. PMID: 28606712.
    View in: PubMed
  12. Husni ME, Merola JF, Davin S. The psychosocial burden of psoriatic arthritis. Semin Arthritis Rheum. 2017 Dec; 47(3):351-360. PMID: 28802776.
    View in: PubMed
  13. Menter A, Warren RB, Langley RG, Merola JF, Kerr LN, Dennehy EB, Shrom D, Amato D, Okubo Y, Reich K. Efficacy of ixekizumab compared to etanercept and placebo in patients with moderate-to-severe plaque psoriasis and non-pustular palmoplantar involvement: results from three phase 3 trials (UNCOVER-1, UNCOVER-2 and UNCOVER-3). J Eur Acad Dermatol Venereol. 2017 Oct; 31(10):1686-1692. PMID: 28322474.
    View in: PubMed
  14. Merola JF, Elewski B, Tatulych S, Lan S, Tallman A, Kaur M. Efficacy of tofacitinib for the treatment of nail psoriasis: Two 52-week, randomized, controlled phase 3 studies in patients with moderate-to-severe plaque psoriasis. J Am Acad Dermatol. 2017 Jul; 77(1):79-87.e1. PMID: 28396102.
    View in: PubMed
  15. Thorlacius L, Ingram JR, Garg A, Villumsen B, Esmann S, Kirby JS, Gottlieb AB, Merola JF, Dellavalle R, Christensen R, Jemec GB. Protocol for the development of a core domain set for hidradenitis suppurativa trial outcomes. BMJ Open. 2017 Feb 20; 7(2):e014733. PMID: 28219961.
    View in: PubMed
  16. Haber JS, Merola JF, Werth VP. Classifying discoid lupus erythematosus: background, gaps, and difficulties. Int J Womens Dermatol. 2017 Mar; 3(1 Suppl):S62-S66. PMID: 28492042.
    View in: PubMed
  17. Merola JF, Lockshin B, Mody EA. Switching biologics in the treatment of psoriatic arthritis. Semin Arthritis Rheum. 2017 Aug; 47(1):29-37. PMID: 28363434.
    View in: PubMed
  18. Elman SA, Merola JF, Armstrong AW, Duffin KC, Latella J, Garg A, Gottlieb AB. The International Dermatology Outcome Measures (IDEOM) Initiative: A Review and Update. J Drugs Dermatol. 2017 Feb 01; 16(2):119-124. PMID: 28300853.
    View in: PubMed
  19. Armstrong AW, Siegel MP, Bagel J, Boh EE, Buell M, Cooper KD, Callis Duffin K, Eichenfield LF, Garg A, Gelfand JM, Gottlieb AB, Koo JY, Korman NJ, Krueger GG, Lebwohl MG, Leonardi CL, Mandelin AM, Menter MA, Merola JF, Pariser DM, Prussick RB, Ryan C, Shah KN, Weinberg JM, Williams MO, Wu JJ, Yamauchi PS, Van Voorhees AS. From the Medical Board of the National Psoriasis Foundation: Treatment targets for plaque psoriasis. J Am Acad Dermatol. 2017 Feb; 76(2):290-298. PMID: 27908543.
    View in: PubMed
  20. Merola J, Yoo PS, Schaub J, Smith JD, Rodriguez-Davalos MI, Tichy E, Mulligan DC, Asch W, Formica R, Kashgarian M, Kulkarni S. Belatacept and Eculizumab for Treatment of Calcineurin Inhibitor-induced Thrombotic Microangiopathy After Kidney Transplantation: Case Report. Transplant Proc. 2016 Nov; 48(9):3106-3108. PMID: 27932157.
    View in: PubMed
  21. Kurtzman DJ, Wright NA, Lin J, Femia AN, Merola JF, Patel M, Vleugels RA. Tofacitinib Citrate for Refractory Cutaneous Dermatomyositis: An Alternative Treatment. JAMA Dermatol. 2016 Aug 01; 152(8):944-5. PMID: 27120749.
    View in: PubMed
  22. Cohen JM, Halim K, Joyce CJ, Patel M, Qureshi AA, Merola JF. Shedding Light on the "Hidden Psoriasis": A Pilot Study of the Inverse Psoriasis Burden of Disease (IPBOD) Questionnaire. J Drugs Dermatol. 2016 Aug 01; 15(8):1011-6. PMID: 27538004.
    View in: PubMed
  23. Elman SA, Ware JH, Gottlieb AB, Merola JF. Adaptive Clinical Trial Design: An Overview and Potential Applications in Dermatology. J Invest Dermatol. 2016 Jul; 136(7):1325-1329. PMID: 27157773.
    View in: PubMed
  24. Merola JF, Armstrong AW, Saraiya A, Latella J, Garg A, Callis Duffin K, Gottlieb AB. International Dermatology Outcome Measures Initiative as Applied to Psoriatic Disease Outcomes: An Update. J Rheumatol. 2016 May; 43(5):959-60. PMID: 27134269.
    View in: PubMed
  25. Paek SY, Thompson JM, Qureshi AA, Merola JF, Husni ME. Comprehensive Assessment of the Psoriasis Patient (CAPP): A Report from the GRAPPA 2015 Annual Meeting. J Rheumatol. 2016 May; 43(5):961-4. PMID: 27134270.
    View in: PubMed
  26. Greb JE, Merola J, Garg A, Latella J, Howard L, Acharya N, Gottlieb AB. The Psoriatic Disease Payer Advisory Panel. J Drugs Dermatol. 2016 May 01; 15(5):641-4. PMID: 27168273.
    View in: PubMed
  27. Xue Y, Cohen JM, Wright NA, Merola JF. Skin Signs of Rheumatoid Arthritis and its Therapy-Induced Cutaneous Side Effects. Am J Clin Dermatol. 2016 Apr; 17(2):147-62. PMID: 26649439.
    View in: PubMed
  28. Haber JS, Merola JF, Werth VP. Classifying discoid lupus erythematosus: background, gaps, and difficulties. Int J Womens Dermatol. 2016 Mar; 2(1):8-12. PMID: 28491994.
    View in: PubMed
  29. Elman SA, Nyberg F, Furukawa F, Goodfield M, Hasegawa M, Marinovic B, Szepietowski J, Dutz J, Werth VP, Merola JF. Developing classification criteria for discoid lupus erythematosus: an update from the World Congress of Dermatology 2015 meeting. Int J Womens Dermatol. 2016 Jun; 2(2):44-45. PMID: 28492003.
    View in: PubMed
  30. Merola JF, Li T, Li WQ, Cho E, Qureshi AA. Prevalence of psoriasis phenotypes among men and women in the USA. Clin Exp Dermatol. 2016 Jul; 41(5):486-9. PMID: 26890045; PMCID: PMC4915990 [Available on 07/01/17].
  31. Song JS, Halim K, Vleugels RA, Merola JF. Dapsone for treatment of erythema nodosum. Dermatol Online J. 2016 Feb 17; 22(2). PMID: 27267197.
    View in: PubMed
  32. Timerman D, Devlin PM, Nambudiri VE, Wright NA, Vleugels RA, Clark RA, Kupper TS, Merola JF, Patel M. Novel application of high-dose rate brachytherapy for severe, recalcitrant palmoplantar pustulosis. Clin Exp Dermatol. 2016 Jul; 41(5):498-501. PMID: 26848819.
    View in: PubMed
  33. Wright NA, Mazori DR, Patel M, Merola JF, Femia AN, Vleugels RA. Epidemiology and Treatment of Eosinophilic Fasciitis: An Analysis of 63 Patients From 3 Tertiary Care Centers. JAMA Dermatol. 2016 Jan; 152(1):97-9. PMID: 26559760.
    View in: PubMed
  34. Sheu JS, Divito SJ, Enamandram M, Merola JF. Dapsone Therapy for Pustular Psoriasis: Case Series and Review of the Literature. Dermatology. 2016; 232(1):97-101. PMID: 26465742.
    View in: PubMed
  35. Patel M, Cohen JM, Wright NA, Merola JF, Qureshi AA, Vleugels RA. Epidemiology of concomitant psoriasis and hidradenitis suppurativa (HS): experience of a tertiary medical center. J Am Acad Dermatol. 2015 Oct; 73(4):701-2. PMID: 26369843.
    View in: PubMed
  36. Jung DH, Nadol JB, Folkerth RD, Merola JF. Histopathology of the Inner Ear in a Case With Recent Onset of Cogan's Syndrome: Evidence for Vasculitis. Ann Otol Rhinol Laryngol. 2016 Jan; 125(1):20-4. PMID: 26195577.
    View in: PubMed
  37. Geller BJ, Stone RM, Merola JF, Levy BD, Loscalzo J. CLINICAL PROBLEM-SOLVING. A Man with Fever, Cough, and Rash. N Engl J Med. 2015 Jul 02; 373(1):74-80. PMID: 26132944.
    View in: PubMed
  38. Sheu J, Divito SJ, Hoffman EP, Frank NY, Merola JF. Mosaic focal dermal hypoplasia caused by a novel somatic mutation in PORCN detected in affected skin. Br J Dermatol. 2015 Aug; 173(2):568-70. PMID: 25640089.
    View in: PubMed
  39. Goyal A, Goyal K, Merola JF. Screening and vaccinations in patients requiring systemic immunosuppression: an update for dermatologists. Am J Clin Dermatol. 2015 Jun; 16(3):179-95. PMID: 25854805.
    View in: PubMed
  40. Cohen JM, Husni ME, Qureshi AA, Merola JF. Psoriatic arthritis: it's as easy as "PSA". J Am Acad Dermatol. 2015 May; 72(5):905-6. PMID: 25890458.
    View in: PubMed
  41. Rao DA, Wei K, Merola JF, O'Brien WR, Takvorian SU, Dellaripa PF, Schur PH. Myeloperoxidase-antineutrophil Cytoplasmic Antibodies (MPO-ANCA) and Proteinase 3-ANCA without Immunofluorescent ANCA Found by Routine Clinical Testing. J Rheumatol. 2015 May; 42(5):847-52. PMID: 25834211.
    View in: PubMed
  42. Merola JF, Nyberg F, Furukawa F, Goodfield MJ, Hasegawa M, Marinovic B, Szepietowski J, Dutz J, Werth VP. Redefining cutaneous lupus erythematosus: a proposed international consensus approach and results of a preliminary questionnaire. Lupus Sci Med. 2015; 2(1):e000085. PMID: 25861460; PMCID: PMC4379883.
  43. Varada S, Gottlieb AB, Merola JF, Saraiya AR, Tintle SJ. Treatment of coexistent psoriasis and lupus erythematosus. J Am Acad Dermatol. 2015 Feb; 72(2):253-60. PMID: 25486913.
    View in: PubMed
  44. Gottlieb AB, Levin AA, Armstrong AW, Abernethy A, Duffin KC, Bhushan R, Garg A, Merola JF, Maccarone M, Christensen R. The International Dermatology Outcome Measures Group: formation of patient-centered outcome measures in dermatology. J Am Acad Dermatol. 2015 Feb; 72(2):345-8. PMID: 25486914.
    View in: PubMed
  45. Sheu J, Kattapuram SV, Stankiewicz JM, Merola JF. Eosinophilic fasciitis-like disorder developing in the setting of multiple sclerosis therapy. J Drugs Dermatol. 2014 Sep; 13(9):1144-7. PMID: 25226017.
    View in: PubMed
  46. Patel M, Liu SW, Qureshi A, Merola JF. The Brigham Scalp Nail Inverse Palmoplantar Psoriasis Composite Index (B-SNIPI): a novel index to measure all non-plaque psoriasis subsets. J Rheumatol. 2014 Jun; 41(6):1230-2. PMID: 24882859.
    View in: PubMed
  47. Gottlieb AB, Armstrong AW, Christensen R, Garg A, Duffin KC, Boehncke WH, Merola JF, Gladman DD, Mease PJ, Swerlick RA, Rosen CF, Abernethy A. The International Dermatology Outcome Measures initiative as applied to psoriatic disease outcomes: a report from the GRAPPA 2013 meeting. J Rheumatol. 2014 Jun; 41(6):1227-9. PMID: 24882858.
    View in: PubMed
  48. Takvorian SU, Merola JF, Costenbader KH. Cigarette smoking, alcohol consumption and risk of systemic lupus erythematosus. Lupus. 2014 May; 23(6):537-44. PMID: 24763538.
    View in: PubMed
  49. Boehncke WH, Qureshi A, Merola JF, Tha├ži D, Krueger GG, Walsh J, Kim N, Gottlieb AB. Diagnosing and treating psoriatic arthritis: an update. Br J Dermatol. 2014 Apr; 170(4):772-86. PMID: 24266754.
    View in: PubMed
  50. Merola JF, Husni ME, Qureshi AA. Psoriatic arthritis screening tools: study design and methodological challenges. Br J Dermatol. 2014 Apr; 170(4):994-5. PMID: 24400947.
    View in: PubMed
  51. Merola JF, Han J, Li T, Qureshi AA. No association between vitamin D intake and incident psoriasis among US women. Arch Dermatol Res. 2014 Apr; 306(3):305-7. PMID: 24232773.
    View in: PubMed
  52. Merola JF, Wu S, Han J, Choi HK, Qureshi AA. Psoriasis, psoriatic arthritis and risk of gout in US men and women. Ann Rheum Dis. 2015 Aug; 74(8):1495-500. PMID: 24651620; PMCID: PMC4224633.
  53. Merola JF, Bermas B, Lu B, Karlson EW, Massarotti E, Schur PH, Costenbader KH. Clinical manifestations and survival among adults with (SLE) according to age at diagnosis. Lupus. 2014 Jul; 23(8):778-84. PMID: 24608964; PMCID: PMC4157121.
  54. Eastham AB, Liang CA, Femia AN, Lee TC, Vleugels RA, Merola JF. Lupus erythematosus panniculitis-induced facial atrophy: effective treatment with poly-L-lactic acid and hyaluronic acid dermal fillers. J Am Acad Dermatol. 2013 Nov; 69(5):e260-2. PMID: 24124855.
    View in: PubMed
  55. Frankel HC, Sharon VR, Vleugels RA, Merola JF, Qureshi AA. Lower-dose thalidomide therapy effectively treats cutaneous lupus erythematosus but is limited by neuropathic toxicity. Int J Dermatol. 2013 Nov; 52(11):1407-9. PMID: 24164159.
    View in: PubMed
  56. Femia AN, Eastham AB, Lam C, Merola JF, Qureshi AA, Vleugels RA. Intravenous immunoglobulin for refractory cutaneous dermatomyositis: a retrospective analysis from an academic medical center. J Am Acad Dermatol. 2013 Oct; 69(4):654-7. PMID: 24034377.
    View in: PubMed
  57. Nguyen K, Vleugels RA, Velez NF, Merola JF, Qureshi AA. Psoriasiform reactions to anti-tumor necrosis factor a therapy. J Clin Rheumatol. 2013 Oct; 19(7):377-81. PMID: 24048106.
    View in: PubMed
  58. Merola JF, Husni ME, Qureshi AA. Screening instruments for psoriatic arthritis. J Rheumatol. 2013 Sep; 40(9):1623. PMID: 23997000.
    View in: PubMed
  59. Merola JF, Prystowsky SD, Iversen C, Gomez-Puerta JA, Norton T, Tsao P, Massarotti E, Schur P, Bermas B, Costenbader KH. Association of discoid lupus erythematosus with other clinical manifestations among patients with systemic lupus erythematosus. J Am Acad Dermatol. 2013 Jul; 69(1):19-24. PMID: 23541758; PMCID: PMC3686921.
  60. De Souza A, Strober BE, Merola JF, Oliver S, Franks AG. Apremilast for discoid lupus erythematosus: results of a phase 2, open-label, single-arm, pilot study. J Drugs Dermatol. 2012 Oct; 11(10):1224-6. PMID: 23134988.
    View in: PubMed
  61. Merola JF, Ghoroghchian PP, Samuels MA, Levy BD, Loscalzo J. Clinical problem-solving. At a loss. N Engl J Med. 2012 Jul 05; 367(1):67-72. PMID: 22762321.
    View in: PubMed
  62. Vaidya A, Ghoroghchian PP, Merola JF, Samuels MA. Interactive medical case. At a loss. N Engl J Med. 2012 Jun 14; 366(24):e37. PMID: 22694019.
    View in: PubMed
  63. Girouard SD, Falk RH, Rennke HG, Merola JF. Hidradenitis suppurativa resulting in systemic amyloid A amyloidosis: a case report and review of the literature. Dermatol Online J. 2012 Jan 15; 18(1):2. PMID: 22301039.
    View in: PubMed
  64. Merola JF, Chang CA, Sanchez MR, Prystowsky SD. Is chronic cutaneous discoid lupus protective against severe renal disease in patients with systemic lupus erythematosus? J Drugs Dermatol. 2011 Dec; 10(12):1413-20. PMID: 22134565.
    View in: PubMed
  65. Click J, Gee S, Cortes R, Gedmintas L, Merola JF, Bykerk V, Saveedra A. Levamisole-induced retiform purpura. J Drugs Dermatol. 2011 Feb; 10(2):217. PMID: 21361080.
    View in: PubMed
  66. Farley-Loftus R, Mahlberg M, Merola JF, Votava HJ, Meehan S, Stein J, Shupack JL. Generalized discoid lupus erythematosus. Dermatol Online J. 2009 Aug 15; 15(8):18. PMID: 19891926.
    View in: PubMed
  67. Warycha M, Patel R, Meehan S, Merola JF. Familial benign chronic pemphigus (Hailey-Hailey disease). Dermatol Online J. 2009 Aug 15; 15(8):15. PMID: 19891923.
    View in: PubMed
  68. Merola JF, Meehan S, Walters RF, Brown L. Exogenous ochronosis. Dermatol Online J. 2008 Oct 15; 14(10):6. PMID: 19061605.
    View in: PubMed
  69. Bakst R, Merola JF, Franks AG, Sanchez M. Raynaud's phenomenon: pathogenesis and management. J Am Acad Dermatol. 2008 Oct; 59(4):633-53. PMID: 18656283.
    View in: PubMed
  70. Merola JF, Pulitzer M, Rosenman K, Brownell I. Cutaneous Rosai-Dorfman disease. Dermatol Online J. 2008 May 15; 14(5):8. PMID: 18627744.
    View in: PubMed
  71. Merola JF, Mengden SJ, Soldano A, Rosenman K. Eruptive xanthomas. Dermatol Online J. 2008 May 15; 14(5):10. PMID: 18627746.
    View in: PubMed
  72. Hatsell S, Medina L, Merola J, Haltiwanger R, Cowin P. Plakoglobin is O-glycosylated close to the N-terminal destruction box. J Biol Chem. 2003 Sep 26; 278(39):37745-52. PMID: 12847106.
    View in: PubMed
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