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Keywords
Last Name
Institution

profileLori Michelle Burtz Laffel, M.D.

TitleProfessor of Pediatrics
InstitutionJoslin Diabetes Center
DepartmentPediatrics
AddressJoslin Diabetes Center
One Joslin Place
Boston MA 02215
Phone617/732-2603
Fax617/732-2451
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The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
R01DK095273     (ANDERSON, BARBARA JANE)Aug 1, 2012 - May 31, 2016
NIH/NIDDK
Optimizing Self-Management Adherence and Glycemic Control in Older Teens with T1D
Role: Co-Principal Investigator

K12DK094721     (LAFFEL, LORI M)Sep 16, 2011 - Jun 30, 2021
NIH/NIDDK
CAREER DEVELOPMENT IN DIABETES RESEARCH FOR PEDIATRIC ENDOCRINOLOGISTS
Role: Principal Investigator

R01DK089349     (LAFFEL, LORI M)Sep 30, 2010 - Aug 31, 2014
NIH/NIDDK
Optimizing CGM Use and Metabolic Outcomes in Youth with Type 1 Diabetes
Role: Principal Investigator

K12DK063696     (LAFFEL, LORI M)Sep 30, 2002 - Jun 30, 2010
NIH/NIDDK
Career Development in Diabetes for Pediatric Endocrinolo
Role: Principal Investigator

T32DK063702     (LAFFEL, LORI M)Sep 30, 2002 - Jun 30, 2008
NIH/NIDDK
Training Grant in Diabetes for Pediatric Endocrinologis*
Role: Principal Investigator
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in the eagle-i Network. To update or add resource records, contact
eagle-i@hms.harvard.edu.

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Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Boot M, Volkening LK, Butler DA, Laffel LM. The impact of blood glucose and HbA(1c) goals on glycaemic control in children and adolescents with Type 1 diabetes. Diabet Med. 2013 Mar; 30(3):333-7. PMID: 23190135; PMCID: PMC3614346.
  2. Sands AL, Higgins LA, Mehta SN, Nansel TR, Lipsky LM, Laffel LM. Associations of youth and parent weight status with reported versus predicted daily energy intake and hemoglobin A1c in youth with type 1 diabetes mellitus. J Diabetes Sci Technol. 2013 Jan 01; 7(1):263-70. PMID: 23439184; PMCID: PMC3692240.
  3. Mehta SN, Goldfine AB, Abrahamson MJ, DiVincenzo R, Laffel LM. Changing prescribing patterns of type 2 diabetes medications from 2002-2010: an electronic health record-based evaluation. J Diabetes Sci Technol. 2013; 7(1):119-22. PMID: 23439167; PMCID: PMC3692223.
  4. Garvey KC, Markowitz JT, Laffel LM. Transition to adult care for youth with type 1 diabetes. Curr Diab Rep. 2012 Oct; 12(5):533-41. PMID: 22922877; PMCID: PMC4080881.
  5. Katz ML, Volkening LK, Anderson BJ, Laffel LM. Contemporary rates of severe hypoglycaemia in youth with type 1 diabetes: variability by insulin regimen. Diabet Med. 2012 Jul; 29(7):926-32. PMID: 22417321; PMCID: PMC3597100.
  6. Garvey KC, Wolpert HA, Rhodes ET, Laffel LM, Kleinman K, Beste MG, Wolfsdorf JI, Finkelstein JA. Health care transition in patients with type 1 diabetes: young adult experiences and relationship to glycemic control. Diabetes Care. 2012 Aug; 35(8):1716-22. PMID: 22699289; PMCID: PMC3402251.
  7. Rovner AJ, Nansel TR, Mehta SN, Higgins LA, Haynie DL, Laffel LM. Development and validation of the type 1 diabetes nutrition knowledge survey. Diabetes Care. 2012 Aug; 35(8):1643-7. PMID: 22665217; PMCID: PMC3402267.
  8. Markowitz JT, Pratt K, Aggarwal J, Volkening LK, Laffel LM. Psychosocial correlates of continuous glucose monitoring use in youth and adults with type 1 diabetes and parents of youth. Diabetes Technol Ther. 2012 Jun; 14(6):523-6. PMID: 22524590; PMCID: PMC3359621.
  9. Markowitz JT, Volkening LK, Butler DA, Antisdel-Lomaglio J, Anderson BJ, Laffel LM. Re-examining a measure of diabetes-related burden in parents of young people with Type 1 diabetes: the Problem Areas in Diabetes Survey - Parent Revised version (PAID-PR). Diabet Med. 2012 Apr; 29(4):526-30. PMID: 21883443; PMCID: PMC3510480.
  10. Markowitz JT, Laffel LM. Transitions in care: support group for young adults with Type 1 diabetes. Diabet Med. 2012 Apr; 29(4):522-5. PMID: 22150392; PMCID: PMC3509361.
  11. Rhodes ET, Prosser LA, Hoerger TJ, Lieu T, Ludwig DS, Laffel LM. Estimated morbidity and mortality in adolescents and young adults diagnosed with Type 2 diabetes mellitus. Diabet Med. 2012 Apr; 29(4):453-63. PMID: 22150528.
    View in: PubMed
  12. Laffel L, Chang N, Grey M, Hale D, Higgins L, Hirst K, Izquierdo R, Larkin M, Macha C, Pham T, Wauters A, Weinstock RS. Metformin monotherapy in youth with recent onset type 2 diabetes: experience from the prerandomization run-in phase of the TODAY study. Pediatr Diabetes. 2012 Aug; 13(5):369-75. PMID: 22369102; PMCID: PMC3371323.
  13. Phillip M, Danne T, Shalitin S, Buckingham B, Laffel L, Tamborlane W, Battelino T. Use of continuous glucose monitoring in children and adolescents (*). Pediatr Diabetes. 2012 May; 13(3):215-28. PMID: 22284160.
    View in: PubMed
  14. Rhodes ET, Goran MI, Lieu TA, Lustig RH, Prosser LA, Songer TJ, Weigensberg MJ, Weinstock RS, Gonzalez T, Rawluk K, Zoghbi RM, Ludwig DS, Laffel LM. Health-related quality of life in adolescents with or at risk for type 2 diabetes mellitus. J Pediatr. 2012 Jun; 160(6):911-7. PMID: 22217471.
    View in: PubMed
  15. Alleyn CR, Laffel LM, Volkening LK, Anderson BJ, Nansel TR, Wysocki T, Weissberg-Benchell J. Comparison of longitudinal point-of-care and high-performance liquid chromatography HbA1c measurements in a multi-centre trial. Diabet Med. 2011 Dec; 28(12):1525-9. PMID: 21824185; PMCID: PMC3220776.
  16. Katz ML, Laffel LM, Perrin JM, Kuhlthau K. Impact of type 1 diabetes mellitus on the family is reduced with the medical home, care coordination, and family-centered care. J Pediatr. 2012 May; 160(5):861-7. PMID: 22133424; PMCID: PMC3328639.
  17. Peters A, Laffel L. Diabetes care for emerging adults: recommendations for transition from pediatric to adult diabetes care systems: a position statement of the American Diabetes Association, with representation by the American College of Osteopathic Family Physicians, the American Academy of Pediatrics, the American Association of Clinical Endocrinologists, the American Osteopathic Association, the Centers for Disease Control and Prevention, Children with Diabetes, The Endocrine Society, the International Society for Pediatric and Adolescent Diabetes, Juvenile Diabetes Research Foundation International, the National Diabetes Education Program, and the Pediatric Endocrine Society (formerly Lawson Wilkins Pediatric Endocrine Society). Diabetes Care. 2011 Nov; 34(11):2477-85. PMID: 22025785; PMCID: PMC3198284.
  18. Tansey M, Laffel L, Cheng J, Beck R, Coffey J, Huang E, Kollman C, Lawrence J, Lee J, Ruedy K, Tamborlane W, Wysocki T, Xing D. Satisfaction with continuous glucose monitoring in adults and youths with Type 1 diabetes. Diabet Med. 2011 Sep; 28(9):1118-22. PMID: 21692844.
    View in: PubMed
  19. Markowitz JT, Laffel LM, Volkening LK, Anderson BJ, Nansel TR, Weissberg-Benchell J, Wysocki T. Validation of an abbreviated adherence measure for young people with Type 1 diabetes. Diabet Med. 2011 Sep; 28(9):1113-7. PMID: 21843307; PMCID: PMC3300068.
  20. Wilson DM, Xing D, Cheng J, Beck RW, Hirsch I, Kollman C, Laffel L, Lawrence JM, Mauras N, Ruedy KJ, Tsalikian E, Wolpert H. Persistence of individual variations in glycated hemoglobin: analysis of data from the Juvenile Diabetes Research Foundation Continuous Glucose Monitoring Randomized Trial. Diabetes Care. 2011 Jun; 34(6):1315-7. PMID: 21505208; PMCID: PMC3114360.
  21. Rhodes ET, Prosser LA, Lieu TA, Songer TJ, Ludwig DS, Laffel LM. Preferences for type 2 diabetes health states among adolescents with or at risk of type 2 diabetes mellitus. Pediatr Diabetes. 2011 Dec; 12(8):724-32. PMID: 21489091.
    View in: PubMed
  22. Xing D, Kollman C, Beck RW, Tamborlane WV, Laffel L, Buckingham BA, Wilson DM, Weinzimer S, Fiallo-Scharer R, Ruedy KJ. Optimal sampling intervals to assess long-term glycemic control using continuous glucose monitoring. Diabetes Technol Ther. 2011 Mar; 13(3):351-8. PMID: 21299401.
    View in: PubMed
  23. Fiallo-Scharer R, Cheng J, Beck RW, Buckingham BA, Chase HP, Kollman C, Laffel L, Lawrence JM, Mauras N, Tamborlane WV, Wilson DM, Wolpert H. Factors predictive of severe hypoglycemia in type 1 diabetes: analysis from the Juvenile Diabetes Research Foundation continuous glucose monitoring randomized control trial dataset. Diabetes Care. 2011 Mar; 34(3):586-90. PMID: 21266651; PMCID: PMC3041185.
  24. Wilson DM, Xing D, Beck RW, Block J, Bode B, Fox LA, Hirsch I, Kollman C, Laffel L, Ruedy KJ, Steffes M, Tamborlane WV. Hemoglobin A1c and mean glucose in patients with type 1 diabetes: analysis of data from the Juvenile Diabetes Research Foundation continuous glucose monitoring randomized trial. Diabetes Care. 2011 Mar; 34(3):540-4. PMID: 21266647; PMCID: PMC3041177.
  25. Ingerski LM, Laffel L, Drotar D, Repaske D, Hood KK. Correlates of glycemic control and quality of life outcomes in adolescents with type 1 diabetes. Pediatr Diabetes. 2010 Dec; 11(8):563-71. PMID: 20149122.
    View in: PubMed
  26. Laffel L. Exercise: it isn't just child's play when it comes to managing type 1 diabetes. J Pediatr. 2010 Nov; 157(5):701-3. PMID: 20850760.
    View in: PubMed
  27. Rovner AJ, Mehta SN, Haynie DL, Robinson EM, Pound HJ, Butler DA, Laffel LM, Nansel TR. Perceived benefits, barriers, and strategies of family meals among children with type 1 diabetes mellitus and their parents: focus-group findings. J Am Diet Assoc. 2010 Sep; 110(9):1302-6. PMID: 20800121; PMCID: PMC2930892.
  28. Beck RW, Lawrence JM, Laffel L, Wysocki T, Xing D, Huang ES, Ives B, Kollman C, Lee J, Ruedy KJ, Tamborlane WV. Quality-of-life measures in children and adults with type 1 diabetes: Juvenile Diabetes Research Foundation Continuous Glucose Monitoring randomized trial. Diabetes Care. 2010 Oct; 33(10):2175-7. PMID: 20696865; PMCID: PMC2945155.
  29. Chase HP, Beck RW, Xing D, Tamborlane WV, Coffey J, Fox LA, Ives B, Keady J, Kollman C, Laffel L, Ruedy KJ. Continuous glucose monitoring in youth with type 1 diabetes: 12-month follow-up of the Juvenile Diabetes Research Foundation continuous glucose monitoring randomized trial. Diabetes Technol Ther. 2010 Jul; 12(7):507-15. PMID: 20597824.
    View in: PubMed
  30. Klingensmith GJ, Pyle L, Arslanian S, Copeland KC, Cuttler L, Kaufman F, Laffel L, Marcovina S, Tollefsen SE, Weinstock RS, Linder B. The presence of GAD and IA-2 antibodies in youth with a type 2 diabetes phenotype: results from the TODAY study. Diabetes Care. 2010 Sep; 33(9):1970-5. PMID: 20519658; PMCID: PMC2928346.
  31. Vesco AT, Anderson BJ, Laffel LM, Dolan LM, Ingerski LM, Hood KK. Responsibility sharing between adolescents with type 1 diabetes and their caregivers: importance of adolescent perceptions on diabetes management and control. J Pediatr Psychol. 2010 Nov; 35(10):1168-77. PMID: 20444852; PMCID: PMC2955833.
  32. Huang ES, O'Grady M, Basu A, Winn A, John P, Lee J, Meltzer D, Kollman C, Laffel L, Tamborlane W, Weinzimer S, Wysocki T. The cost-effectiveness of continuous glucose monitoring in type 1 diabetes. Diabetes Care. 2010 Jun; 33(6):1269-74. PMID: 20332354; PMCID: PMC2875436.
  33. Markowitz JT, Butler DA, Volkening LK, Antisdel JE, Anderson BJ, Laffel LM. Brief screening tool for disordered eating in diabetes: internal consistency and external validity in a contemporary sample of pediatric patients with type 1 diabetes. Diabetes Care. 2010 Mar; 33(3):495-500. PMID: 20032278; PMCID: PMC2827495.
  34. Markowitz JT, Lowe MR, Volkening LK, Laffel LM. Self-reported history of overweight and its relationship to disordered eating in adolescent girls with Type 1 diabetes. Diabet Med. 2009 Nov; 26(11):1165-71. PMID: 19929996; PMCID: PMC2840636.
  35. Brink S, Laffel L, Likitmaskul S, Liu L, Maguire AM, Olsen B, Silink M, Hanas R. Sick day management in children and adolescents with diabetes. Pediatr Diabetes. 2009 Sep; 10 Suppl 12:146-53. PMID: 19754625.
    View in: PubMed
  36. Williams LB, Laffel LM, Hood KK. Diabetes-specific family conflict and psychological distress in paediatric Type 1 diabetes. Diabet Med. 2009 Sep; 26(9):908-14. PMID: 19719712.
    View in: PubMed
  37. Beck RW, Buckingham B, Miller K, Wolpert H, Xing D, Block JM, Chase HP, Hirsch I, Kollman C, Laffel L, Lawrence JM, Milaszewski K, Ruedy KJ, Tamborlane WV. Factors predictive of use and of benefit from continuous glucose monitoring in type 1 diabetes. Diabetes Care. 2009 Nov; 32(11):1947-53. PMID: 19675206; PMCID: PMC2768196.
  38. Bode B, Beck RW, Xing D, Gilliam L, Hirsch I, Kollman C, Laffel L, Ruedy KJ, Tamborlane WV, Weinzimer S, Wolpert H. Sustained benefit of continuous glucose monitoring on A1C, glucose profiles, and hypoglycemia in adults with type 1 diabetes. Diabetes Care. 2009 Nov; 32(11):2047-9. PMID: 19675193; PMCID: PMC2768224.
  39. Anderson BJ, Holmbeck G, Iannotti RJ, McKay SV, Lochrie A, Volkening LK, Laffel L. Dyadic measures of the parent-child relationship during the transition to adolescence and glycemic control in children with type 1 diabetes. Fam Syst Health. 2009 Jun; 27(2):141-52. PMID: 19630455; PMCID: PMC2843423.
  40. Beck RW, Hirsch IB, Laffel L, Tamborlane WV, Bode BW, Buckingham B, Chase P, Clemons R, Fiallo-Scharer R, Fox LA, Gilliam LK, Huang ES, Kollman C, Kowalski AJ, Lawrence JM, Lee J, Mauras N, O'Grady M, Ruedy KJ, Tansey M, Tsalikian E, Weinzimer SA, Wilson DM, Wolpert H, Wysocki T, Xing D. The effect of continuous glucose monitoring in well-controlled type 1 diabetes. Diabetes Care. 2009 Aug; 32(8):1378-83. PMID: 19429875; PMCID: PMC2713649.
  41. Weissberg-Benchell J, Nansel T, Holmbeck G, Chen R, Anderson B, Wysocki T, Laffel L. Generic and diabetes-specific parent-child behaviors and quality of life among youth with type 1 diabetes. J Pediatr Psychol. 2009 Oct; 34(9):977-88. PMID: 19270028; PMCID: PMC2782249.
  42. Mehta SN, Quinn N, Volkening LK, Laffel LM. Impact of carbohydrate counting on glycemic control in children with type 1 diabetes. Diabetes Care. 2009 Jun; 32(6):1014-6. PMID: 19244089; PMCID: PMC2681033.
  43. McGrady ME, Laffel L, Drotar D, Repaske D, Hood KK. Depressive symptoms and glycemic control in adolescents with type 1 diabetes: mediational role of blood glucose monitoring. Diabetes Care. 2009 May; 32(5):804-6. PMID: 19228870; PMCID: PMC2671131.
  44. Hanauer DA, Wentzell K, Laffel N, Laffel LM. Computerized Automated Reminder Diabetes System (CARDS): e-mail and SMS cell phone text messaging reminders to support diabetes management. Diabetes Technol Ther. 2009 Feb; 11(2):99-106. PMID: 19848576; PMCID: PMC4504120.
  45. Wysocki T, Nansel TR, Holmbeck GN, Chen R, Laffel L, Anderson BJ, Weissberg-Benchell J. Collaborative involvement of primary and secondary caregivers: associations with youths' diabetes outcomes. J Pediatr Psychol. 2009 Sep; 34(8):869-81. PMID: 19112077; PMCID: PMC2729681.
  46. Nansel TR, Weisberg-Benchell J, Wysocki T, Laffel L, Anderson B. Quality of life in children with Type 1 diabetes: a comparison of general and diabetes-specific measures and support for a unitary diabetes quality-of-life construct. Diabet Med. 2008 Nov; 25(11):1316-23. PMID: 19046222; PMCID: PMC2597420.
  47. Tamborlane WV, Beck RW, Bode BW, Buckingham B, Chase HP, Clemons R, Fiallo-Scharer R, Fox LA, Gilliam LK, Hirsch IB, Huang ES, Kollman C, Kowalski AJ, Laffel L, Lawrence JM, Lee J, Mauras N, O'Grady M, Ruedy KJ, Tansey M, Tsalikian E, Weinzimer S, Wilson DM, Wolpert H, Wysocki T, Xing D. Continuous glucose monitoring and intensive treatment of type 1 diabetes. N Engl J Med. 2008 Oct 2; 359(14):1464-76. PMID: 18779236.
    View in: PubMed
  48. Nansel TR, Anderson BJ, Laffel LM, Simons-Morton BG, Weissberg-Benchell J, Wysocki T, Iannotti RJ, Holmbeck GN, Hood KK, Lochrie AS. A multisite trial of a clinic-integrated intervention for promoting family management of pediatric type 1 diabetes: feasibility and design. Pediatr Diabetes. 2009 Apr; 10(2):105-15. PMID: 18721167; PMCID: PMC2843426.
  49. Butler DA, Zuehlke JB, Tovar A, Volkening LK, Anderson BJ, Laffel LM. The impact of modifiable family factors on glycemic control among youth with type 1 diabetes. Pediatr Diabetes. 2008 Aug; 9(4 Pt 2):373-81. PMID: 18774997.
    View in: PubMed
  50. Nansel TR, Rovner AJ, Haynie D, Iannotti RJ, Simons-Morton B, Wysocki T, Anderson B, Weissberg-Benchell J, Laffel L. Development and validation of the collaborative parent involvement scale for youths with type 1 diabetes. J Pediatr Psychol. 2009 Jan-Feb; 34(1):30-40. PMID: 18567926; PMCID: PMC2626144.
  51. Mehta SN, Volkening LK, Anderson BJ, Nansel T, Weissberg-Benchell J, Wysocki T, Laffel LM. Dietary behaviors predict glycemic control in youth with type 1 diabetes. Diabetes Care. 2008 Jul; 31(7):1318-20. PMID: 18390798; PMCID: PMC2453641.
  52. Wysocki T, Iannotti R, Weissberg-Benchell J, Laffel L, Hood K, Anderson B, Chen R. Diabetes problem solving by youths with type 1 diabetes and their caregivers: measurement, validation, and longitudinal associations with glycemic control. J Pediatr Psychol. 2008 Sep; 33(8):875-84. PMID: 18346973; PMCID: PMC2493510.
  53. Brink S, Laffel L, Likitmaskul S, Liu L, Maguire AM, Olsen B, Silink M, Hanas R. Sick day management in children and adolescents with diabetes. Pediatr Diabetes. 2007 Dec; 8(6):401-7. PMID: 18036069.
    View in: PubMed
  54. Weinzimer SA, Ternand C, Howard C, Chang CT, Becker DJ, Laffel LM. A randomized trial comparing continuous subcutaneous insulin infusion of insulin aspart versus insulin lispro in children and adolescents with type 1 diabetes. Diabetes Care. 2008 Feb; 31(2):210-5. PMID: 17989308.
    View in: PubMed
  55. Bismuth E, Laffel L. Can we prevent diabetic ketoacidosis in children? Pediatr Diabetes. 2007 Oct; 8 Suppl 6:24-33. PMID: 17727382.
    View in: PubMed
  56. Chan YM, Laffel LM. Transition from insulin to glyburide in a 4-month-old girl with neonatal diabetes mellitus caused by a mutation in KCNJ11. Pediatr Diabetes. 2007 Aug; 8(4):235-8. PMID: 17659066.
    View in: PubMed
  57. Laffel LM, Hsu WC, McGill JB, Meneghini L, Volkening LK. Continued use of an integrated meter with electronic logbook maintains improvements in glycemic control beyond a randomized, controlled trial. Diabetes Technol Ther. 2007 Jun; 9(3):254-64. PMID: 17561796.
    View in: PubMed
  58. Wood JR, Laffel LM. Technology and intensive management in youth with type 1 diabetes: state of the art. Curr Diab Rep. 2007 Apr; 7(2):104-13. PMID: 17425914.
    View in: PubMed
  59. Hood KK, Butler DA, Anderson BJ, Laffel LM. Updated and revised Diabetes Family Conflict Scale. Diabetes Care. 2007 Jul; 30(7):1764-9. PMID: 17372149.
    View in: PubMed
  60. Svoren BM, Volkening LK, Butler DA, Moreland EC, Anderson BJ, Laffel LM. Temporal trends in the treatment of pediatric type 1 diabetes and impact on acute outcomes. J Pediatr. 2007 Mar; 150(3):279-85. PMID: 17307546; PMCID: PMC1857326.
  61. Rodacki M, Svoren B, Butty V, Besse W, Laffel L, Benoist C, Mathis D. Altered natural killer cells in type 1 diabetic patients. Diabetes. 2007 Jan; 56(1):177-85. PMID: 17192480.
    View in: PubMed
  62. Laffel L. Improving outcomes with POCT for HbA1c and blood ketone testing. J Diabetes Sci Technol. 2007 Jan; 1(1):133-6. PMID: 19888393; PMCID: PMC2769605.
  63. Wood JR, Moreland EC, Volkening LK, Svoren BM, Butler DA, Laffel LM. Durability of insulin pump use in pediatric patients with type 1 diabetes. Diabetes Care. 2006 Nov; 29(11):2355-60. PMID: 17065667.
    View in: PubMed
  64. Goodwin G, Volkening LK, Laffel LM. Younger age at onset of type 1 diabetes in concordant sibling pairs is associated with increased risk for autoimmune thyroid disease. Diabetes Care. 2006 Jun; 29(6):1397-8. PMID: 16732031.
    View in: PubMed
  65. Hood KK, Huestis S, Maher A, Butler D, Volkening L, Laffel LM. Depressive symptoms in children and adolescents with type 1 diabetes: association with diabetes-specific characteristics. Diabetes Care. 2006 Jun; 29(6):1389-91. PMID: 16732028.
    View in: PubMed
  66. Moreland EC, Volkening LK, Lawlor MT, Chalmers KA, Anderson BJ, Laffel LM. Use of a blood glucose monitoring manual to enhance monitoring adherence in adults with diabetes: a randomized controlled trial. Arch Intern Med. 2006 Mar 27; 166(6):689-95. PMID: 16567610.
    View in: PubMed
  67. Laffel LM, Wentzell K, Loughlin C, Tovar A, Moltz K, Brink S. Sick day management using blood 3-hydroxybutyrate (3-OHB) compared with urine ketone monitoring reduces hospital visits in young people with T1DM: a randomized clinical trial. Diabet Med. 2006 Mar; 23(3):278-84. PMID: 16492211.
    View in: PubMed
  68. Hanauer DA, Wentzell K, Tovar A, Zeuhlke J, Kumar V, Laffel LM. Parent and youth assessments of a handheld wireless device to enhance diabetes mellitus management. Arch Pediatr Adolesc Med. 2006 Mar; 160(3):321. PMID: 16520456.
    View in: PubMed
  69. Stevanovic RD, Price DA, Lansang MC, Fisher ND, Laffel LM, Hollenberg NK. Renin release in response to Renin system blockade: activation of the Renin system in type 1 diabetes mellitus. J Renin Angiotensin Aldosterone Syst. 2005 Sep; 6(2):78-83. PMID: 16470486.
    View in: PubMed
  70. Hood KK, Bennett Johnson S, Carmichael SK, Laffel LM, She JX, Schatz DA. Depressive symptoms in mothers of infants identified as genetically at risk for type 1 diabetes. Diabetes Care. 2005 Aug; 28(8):1898-903. PMID: 16043729.
    View in: PubMed
  71. Ahmed SB, Hovind P, Parving HH, Rossing P, Price DA, Laffel LM, Lansang MC, Stevanovic R, Fisher ND, Hollenberg NK. Oral contraceptives, angiotensin-dependent renal vasoconstriction, and risk of diabetic nephropathy. Diabetes Care. 2005 Aug; 28(8):1988-94. PMID: 16043743.
    View in: PubMed
  72. Lansang MC, Stevanovic R, Price DA, Laffel LM, Hollenberg NK. ACE and non-ACE pathways in the renal vascular response to RAS interruption in type 1 diabetes mellitus. Kidney Int. 2005 Mar; 67(3):1033-7. PMID: 15698442.
    View in: PubMed
  73. Silverstein J, Klingensmith G, Copeland K, Plotnick L, Kaufman F, Laffel L, Deeb L, Grey M, Anderson B, Holzmeister LA, Clark N. Care of children and adolescents with type 1 diabetes: a statement of the American Diabetes Association. Diabetes Care. 2005 Jan; 28(1):186-212. PMID: 15616254.
    View in: PubMed
  74. Hood KK, Butler DA, Volkening LK, Anderson BJ, Laffel LM. The Blood Glucose Monitoring Communication questionnaire: an instrument to measure affect specific to blood glucose monitoring. Diabetes Care. 2004 Nov; 27(11):2610-5. PMID: 15504994.
    View in: PubMed
  75. Moreland EC, Tovar A, Zuehlke JB, Butler DA, Milaszewski K, Laffel LM. The impact of physiological, therapeutic and psychosocial variables on glycemic control in youth with type 1 diabetes mellitus. J Pediatr Endocrinol Metab. 2004 Nov; 17(11):1533-44. PMID: 15570991.
    View in: PubMed
  76. Kumar VS, Wentzell KJ, Mikkelsen T, Pentland A, Laffel LM. The DAILY (Daily Automated Intensive Log for Youth) trial: a wireless, portable system to improve adherence and glycemic control in youth with diabetes. Diabetes Technol Ther. 2004 Aug; 6(4):445-53. PMID: 15320998.
    View in: PubMed
  77. Laffel LM. Challenges and opportunities in diabetes care: improving outcomes with education, disease management, and new technologies. Manag Care. 2004 Apr; 13(4 Suppl):15-8; discussion 19-21. PMID: 15156716.
    View in: PubMed
  78. Hollenberg NK, Stevanovic R, Agarwal A, Lansang MC, Price DA, Laffel LM, Williams GH, Fisher ND. Plasma aldosterone concentration in the patient with diabetes mellitus. Kidney Int. 2004 Apr; 65(4):1435-9. PMID: 15086486.
    View in: PubMed
  79. Laffel LM, Connell A, Vangsness L, Goebel-Fabbri A, Mansfield A, Anderson BJ. General quality of life in youth with type 1 diabetes: relationship to patient management and diabetes-specific family conflict. Diabetes Care. 2003 Nov; 26(11):3067-73. PMID: 14578241.
    View in: PubMed
  80. Svoren BM, Butler D, Levine BS, Anderson BJ, Laffel LM. Reducing acute adverse outcomes in youths with type 1 diabetes: a randomized, controlled trial. Pediatrics. 2003 Oct; 112(4):914-22. PMID: 14523186.
    View in: PubMed
  81. Laffel LM, Vangsness L, Connell A, Goebel-Fabbri A, Butler D, Anderson BJ. Impact of ambulatory, family-focused teamwork intervention on glycemic control in youth with type 1 diabetes. J Pediatr. 2003 Apr; 142(4):409-16. PMID: 12712059.
    View in: PubMed
  82. Hollenberg NK, Price DA, Fisher ND, Lansang MC, Perkins B, Gordon MS, Williams GH, Laffel LM. Glomerular hemodynamics and the renin-angiotensin system in patients with type 1 diabetes mellitus. Kidney Int. 2003 Jan; 63(1):172-8. PMID: 12472780.
    View in: PubMed
  83. Anderson BJ, Vangsness L, Connell A, Butler D, Goebel-Fabbri A, Laffel LM. Family conflict, adherence, and glycaemic control in youth with short duration Type 1 diabetes. Diabet Med. 2002 Aug; 19(8):635-42. PMID: 12147143.
    View in: PubMed
  84. Norris AW, Laffel LM. Avoiding nocturnal hypoglycemia: consideration of an extra injection at bedtime. Ann Intern Med. 2002 Apr 2; 136(7):547-9. PMID: 11926791.
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  85. Scott LJ, Warram JH, Hanna LS, Laffel LM, Ryan L, Krolewski AS. A nonlinear effect of hyperglycemia and current cigarette smoking are major determinants of the onset of microalbuminuria in type 1 diabetes. Diabetes. 2001 Dec; 50(12):2842-9. PMID: 11723069.
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  86. Levine BS, Anderson BJ, Butler DA, Antisdel JE, Brackett J, Laffel LM. Predictors of glycemic control and short-term adverse outcomes in youth with type 1 diabetes. J Pediatr. 2001 Aug; 139(2):197-203. PMID: 11487743.
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  87. Lawlor MT, Laffel LM. New technologies and therapeutic approaches for the management of pediatric diabetes. Curr Diab Rep. 2001 Aug; 1(1):56-66. PMID: 12762958.
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  88. Fineberg SE, Bergenstal RM, Bernstein RM, Laffel LM, Schwartz SL. Use of an automated device for alternative site blood glucose monitoring. Diabetes Care. 2001 Jul; 24(7):1217-20. PMID: 11423505.
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  89. Lansang MC, Price DA, Laffel LM, Osei SY, Fisher ND, Erani D, Hollenberg NK. Renal vascular responses to captopril and to candesartan in patients with type 1 diabetes mellitus. Kidney Int. 2001 Apr; 59(4):1432-8. PMID: 11260405.
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  90. Laffel L. Sick-day management in type 1 diabetes. Endocrinol Metab Clin North Am. 2000 Dec; 29(4):707-23. PMID: 11149158.
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  91. Feng D, Bursell SE, Clermont AC, Lipinska I, Aiello LP, Laffel L, King GL, Tofler GH. von Willebrand factor and retinal circulation in early-stage retinopathy of type 1 diabetes. Diabetes Care. 2000 Nov; 23(11):1694-8. PMID: 11092294.
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  92. Osei SY, Price DA, Laffel LM, Lansang MC, Hollenberg NK. Effect of angiotensin II antagonist eprosartan on hyperglycemia-induced activation of intrarenal renin-angiotensin system in healthy humans. Hypertension. 2000 Jul; 36(1):122-6. PMID: 10904023.
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  93. Laffel L. Another diabetes dilemma. Health News. 2000 Mar; 6(3):3. PMID: 11019671.
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  94. Warram JH, Scott LJ, Hanna LS, Wantman M, Cohen SE, Laffel LM, Ryan L, Krolewski AS. Progression of microalbuminuria to proteinuria in type 1 diabetes: nonlinear relationship with hyperglycemia. Diabetes. 2000 Jan; 49(1):94-100. PMID: 10615955.
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  95. Laffel L. Ketone bodies: a review of physiology, pathophysiology and application of monitoring to diabetes. Diabetes Metab Res Rev. 1999 Nov-Dec; 15(6):412-26. PMID: 10634967.
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  96. Bursell SE, Clermont AC, Aiello LP, Aiello LM, Schlossman DK, Feener EP, Laffel L, King GL. High-dose vitamin E supplementation normalizes retinal blood flow and creatinine clearance in patients with type 1 diabetes. Diabetes Care. 1999 Aug; 22(8):1245-51. PMID: 10480765.
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  97. Anderson BJ, Brackett J, Ho J, Laffel LM. An office-based intervention to maintain parent-adolescent teamwork in diabetes management. Impact on parent involvement, family conflict, and subsequent glycemic control. Diabetes Care. 1999 May; 22(5):713-21. PMID: 10332671.
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  98. Osei SY, Price DA, Fisher ND, Porter L, Laffel LM, Hollenberg NK. Hyperglycemia and angiotensin-mediated control of the renal circulation in healthy humans. Hypertension. 1999 Jan; 33(1 Pt 2):559-64. PMID: 9931165.
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  99. Laffel LM, Brackett J, Ho J, Anderson BJ. Changing the process of diabetes care improves metabolic outcomes and reduces hospitalizations. Qual Manag Health Care. 1998 Sep; 6(4):53-62. PMID: 10339045.
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  100. Wolfsdorf JI, Laffel LM, Crigler JF. Metabolic control and renal dysfunction in type I glycogen storage disease. J Inherit Metab Dis. 1997 Aug; 20(4):559-68. PMID: 9266393.
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  101. Anderson B, Ho J, Brackett J, Finkelstein D, Laffel L. Parental involvement in diabetes management tasks: relationships to blood glucose monitoring adherence and metabolic control in young adolescents with insulin-dependent diabetes mellitus. J Pediatr. 1997 Feb; 130(2):257-65. PMID: 9042129.
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  102. Onuma T, Laffel LM, Angelico MC, Krolewski AS. Apolipoprotein E genotypes and risk of diabetic nephropathy. J Am Soc Nephrol. 1996 Jul; 7(7):1075-8. PMID: 8829124.
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  103. Warram JH, Gearin G, Laffel L, Krolewski AS. Effect of duration of type I diabetes on the prevalence of stages of diabetic nephropathy defined by urinary albumin/creatinine ratio. J Am Soc Nephrol. 1996 Jun; 7(6):930-7. PMID: 8793803.
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  104. Laffel LM, McGill JB, Gans DJ. The beneficial effect of angiotensin-converting enzyme inhibition with captopril on diabetic nephropathy in normotensive IDDM patients with microalbuminuria. North American Microalbuminuria Study Group. Am J Med. 1995 Nov; 99(5):497-504. PMID: 7485207.
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  105. Krolewski AS, Laffel LM, Krolewski M, Quinn M, Warram JH. Glycosylated hemoglobin and the risk of microalbuminuria in patients with insulin-dependent diabetes mellitus. N Engl J Med. 1995 May 11; 332(19):1251-5. PMID: 7708068.
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  106. Wolfsdorf JI, Laffel LM. Diabetes in childhood: predicting the future. Pediatr Ann. 1994 Jun; 23(6):306-12. PMID: 8078708.
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  107. Parker S, Angelico MC, Laffel L, Krolewski AS. Application of denaturing gradient gel electrophoresis to detect DNA sequence differences encoding apolipoprotein E isoforms. Genomics. 1993 Apr; 16(1):245-7. PMID: 8486365.
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  108. Canessa M, Zerbini G, Laffel LM. Sodium activation kinetics of red blood cell Na+/Li+ countertransport in diabetes: methodology and controversy. J Am Soc Nephrol. 1992 Oct; 3(4 Suppl):S41-9. PMID: 1457760.
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  109. Warram JH, Laffel LM, Ganda OP, Christlieb AR. Coronary artery disease is the major determinant of excess mortality in patients with insulin-dependent diabetes mellitus and persistent proteinuria. J Am Soc Nephrol. 1992 Oct; 3(4 Suppl):S104-10. PMID: 1457752.
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  110. Barzilay J, Warram JH, Bak M, Laffel LM, Canessa M, Krolewski AS. Predisposition to hypertension: risk factor for nephropathy and hypertension in IDDM. Kidney Int. 1992 Apr; 41(4):723-30. PMID: 1513093.
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  111. Krolewski AS, Warram JH, Laffel LM. Genetic susceptibility to diabetic nephropathy. Adv Nephrol Necker Hosp. 1992; 21:69-81. PMID: 1566654.
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  112. Wolfsdorf JI, Laffel LM, Pasquarello C, Vernon A, Herskowitz RD. Split-mixed insulin regimen with human ultralente before supper and NPH (isophane) before breakfast in children and adolescents with IDDM. Diabetes Care. 1991 Nov; 14(11):1100-6. PMID: 1797498.
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  113. Warram JH, Laffel LM, Valsania P, Christlieb AR, Krolewski AS. Excess mortality associated with diuretic therapy in diabetes mellitus. Arch Intern Med. 1991 Jul; 151(7):1350-6. PMID: 1823530.
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  114. Laffel L, Warram JH, Krolewski AS. Increased blood pressure and erythrocyte sodium/lithium countertransport activity are not inherited in diabetic nephropathy. Diabetologia. 1991 Jun; 34(6):452-4. PMID: 1884904.
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  115. Krolewski AS, Warram JH, Valsania P, Martin BC, Laffel LM, Christlieb AR. Evolving natural history of coronary artery disease in diabetes mellitus. Am J Med. 1991 Feb 21; 90(2A):56S-61S. PMID: 1994719.
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  116. Wolfsdorf JI, Plotkin RA, Laffel LM, Crigler JF. Continuous glucose for treatment of patients with type 1 glycogen-storage disease: comparison of the effects of dextrose and uncooked cornstarch on biochemical variables. Am J Clin Nutr. 1990 Dec; 52(6):1043-50. PMID: 2239779.
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  117. Derby L, Warram JH, Laffel LM, Krolewski AS. Elevated blood pressure predicts the development of persistent proteinuria in the presence of poor glycemic control, in patients with type I diabetes. Diabete Metab. 1989; 15(5 Pt 2):320-6. PMID: 2612716.
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  118. Krolewski AS, Canessa M, Warram JH, Laffel LM, Christlieb AR, Knowler WC, Rand LI. Predisposition to hypertension and susceptibility to renal disease in insulin-dependent diabetes mellitus. N Engl J Med. 1988 Jan 21; 318(3):140-5. PMID: 3336401.
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  119. Swartz LM, Laffel LM. A teenage girl with cystic fibrosis-related diabetes, diabetic ketoacidosis, and cerebral edema. Pediatr Diabetes. 2008 Aug; 9(4 Pt 2):426-30. PMID: 18775002.
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  120. Mehta SN, Haynie DL, Higgins LA, Bucey NN, Rovner AJ, Volkening LK, Nansel TR, Laffel LM. Emphasis on carbohydrates may negatively influence dietary patterns in youth with type 1 diabetes. Diabetes Care. 2009 Dec; 32(12):2174-6. PMID: 19741186; PMCID: PMC2782971.
  121. Nansel TR, Haynie DL, Lipsky LM, Laffel LM, Mehta SN. Multiple indicators of poor diet quality in children and adolescents with type 1 diabetes are associated with higher body mass index percentile but not glycemic control. J Acad Nutr Diet. 2012 Nov; 112(11):1728-35. PMID: 23102173; PMCID: PMC3985553.
  122. Tse J, Nansel TR, Haynie DL, Mehta SN, Laffel LM. Disordered eating behaviors are associated with poorer diet quality in adolescents with type 1 diabetes. J Acad Nutr Diet. 2012 Nov; 112(11):1810-4. PMID: 23102180; PMCID: PMC3483560.
  123. Lipsky LM, Nansel TR, Haynie DL, Mehta SN, Laffel LM. Associations of food preferences and household food availability with dietary intake and quality in youth with type 1 diabetes. Appetite. 2012 Oct; 59(2):218-23. PMID: 22595289; PMCID: PMC3428468.
  124. Borus JS, Laffel L. Adherence challenges in the management of type 1 diabetes in adolescents: prevention and intervention. Curr Opin Pediatr. 2010 Aug; 22(4):405-11. PMID: 20489639; PMCID: PMC3159529.
  125. Mehta SN, Schwartz N, Wood JR, Svoren BM, Laffel LM. Evaluation of 1,5-anhydroglucitol, hemoglobin A1c, and glucose levels in youth and young adults with type 1 diabetes and healthy controls. Pediatr Diabetes. 2012 May; 13(3):278-84. PMID: 22060802; PMCID: PMC3767297.
  126. Price DA, Porter LE, Gordon M, Fisher ND, De'Oliveira JM, Laffel LM, Passan DR, Williams GH, Hollenberg NK. The paradox of the low-renin state in diabetic nephropathy. J Am Soc Nephrol. 1999 Nov; 10(11):2382-91. PMID: 10541298.
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  127. Lee JM, Rhee K, O'grady MJ, Basu A, Winn A, John P, Meltzer DO, Kollman C, Laffel LM, Lawrence JM, Tamborlane WV, Wysocki T, Xing D, Huang ES. Health utilities for children and adults with type 1 diabetes. Med Care. 2011 Oct; 49(10):924-31. PMID: 21544001; PMCID: PMC3210197.
  128. Alleyn CR, Volkening LK, Wolfson J, Rodriguez-Ventura A, Wood JR, Laffel LM. Occurrence of microalbuminuria in young people with Type 1 diabetes: importance of age and diabetes duration. Diabet Med. 2010 May; 27(5):532-7. PMID: 20536948; PMCID: PMC2966306.
  129. Rhodes ET, Laffel LM, Gonzalez TV, Ludwig DS. Accuracy of administrative coding for type 2 diabetes in children, adolescents, and young adults. Diabetes Care. 2007 Jan; 30(1):141-3. PMID: 17192348.
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  130. Svoren BM, Volkening LK, Wood JR, Laffel LM. Significant vitamin D deficiency in youth with type 1 diabetes mellitus. J Pediatr. 2009 Jan; 154(1):132-4. PMID: 19187735; PMCID: PMC2635941.
  131. Price DA, Lansang MC, Osei SY, Fisher ND, Laffel LM, Hollenberg NK. Type 2 diabetes, obesity, and the renal response to blocking the renin system with irbesartan. Diabet Med. 2002 Oct; 19(10):858-61. PMID: 12358875.
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