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profileHajime Uno, Ph.D.

TitleAssistant Professor of Medicine
InstitutionDana-Farber Cancer Institute
DepartmentMedicine
AddressDana-Farber Cancer Institute
Population Sciences/Medical Oncology, D1112
450 Brookline Ave
Boston MA 02215
Phone6176326893
vCardDownload vCard (login for email)
Other Positions
TitleResearch Scientist
InstitutionHarvard T.H. Chan School of Public Health
DepartmentBiostatistics


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Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Kim DH, Uno H, Wei LJ. Restricted Mean Survival Time as a Measure to Interpret Clinical Trial Results. JAMA Cardiol. 2017 Sep 06. PMID: 28877311.
    View in: PubMed
  2. Horiguchi M, Uno H, Wei LJ. Overall Survival in the Randomized Phase II Study Investigating Pazopanib Versus Weekly Paclitaxel in Relapsed or Progressive Urothelial Cancer. J Clin Oncol. 2017 Aug 11; JCO2017738120. PMID: 28800271.
    View in: PubMed
  3. Ries M, Reynolds MR, Bashkueva K, Crosno K, Capuano S, Prall TM, Wiseman R, O'Connor DH, Rakasz EG, Uno H, Lifson JD, Evans DT. KIR3DL01 upregulation on gut natural killer cells in response to SIV infection of KIR- and MHC class I-defined rhesus macaques. PLoS Pathog. 2017 Jul; 13(7):e1006506. PMID: 28708886.
    View in: PubMed
  4. Dutta A, Uno H, Holman A, Lorenz DR, Wolinsky SM, Gabuzda D. Long-term nitrite inhalant exposure and cancer risk in MSM. AIDS. 2017 May 15; 31(8):1169-1180. PMID: 28441176.
    View in: PubMed
  5. Kastrinos F, Uno H, Ukaegbu C, Alvero C, McFarland A, Yurgelun MB, Kulke MH, Schrag D, Meyerhardt JA, Fuchs CS, Mayer RJ, Ng K, Steyerberg EW, Syngal S. Development and Validation of the PREMM5 Model for Comprehensive Risk Assessment of Lynch Syndrome. J Clin Oncol. 2017 Jul 01; 35(19):2165-2172. PMID: 28489507.
    View in: PubMed
  6. Dutta A, Uno H, Holman A, Lorenz DR, Gabuzda D. Racial differences in prostate cancer risk in young HIV-positive and HIV-negative men: a prospective cohort study. Cancer Causes Control. 2017 Jul; 28(7):767-777. PMID: 28451806.
    View in: PubMed
  7. Lorenz DR, Dutta A, Mukerji SS, Holman A, Uno H, Gabuzda D. Marijuana use impacts midlife cardiovascular events in HIV-infected men. Clin Infect Dis. 2017 Apr 25. PMID: 28449059.
    View in: PubMed
  8. Dutta A, Uno H, Holman A, Lorenz DR, Wolinsky SM, Gabuzda D. Long-term nitrite inhalant exposure and cancer risk in men who have sex with men: a prospective cohort study. AIDS. 2017 Mar 18. PMID: 28323751.
    View in: PubMed
  9. Yurgelun MB, Kulke MH, Fuchs CS, Allen BA, Uno H, Hornick JL, Ukaegbu CI, Brais LK, McNamara PG, Mayer RJ, Schrag D, Meyerhardt JA, Ng K, Kidd J, Singh N, Hartman AR, Wenstrup RJ, Syngal S. Cancer Susceptibility Gene Mutations in Individuals With Colorectal Cancer. J Clin Oncol. 2017 Apr 01; 35(10):1086-1095. PMID: 28135145.
    View in: PubMed
  10. Davoli T, Uno H, Wooten EC, Elledge SJ. Tumor aneuploidy correlates with markers of immune evasion and with reduced response to immunotherapy. Science. 2017 01 20; 355(6322). PMID: 28104840.
    View in: PubMed
  11. Punglia RS, Cronin AM, Uno H, Stout NK, Ozanne EM, Greenberg CC, Frank ES, Schrag D. Association of Regional Intensity of Ductal Carcinoma In Situ Treatment With Likelihood of Breast Preservation. JAMA Oncol. 2017 Jan 01; 3(1):101-104. PMID: 27442038.
    View in: PubMed
  12. Hasegawa T, Uno H, Wei LJ. Safety Study of Salmeterol in Asthma in Adults. N Engl J Med. 2016 Sep 15; 375(11):1097. PMID: 27626533.
    View in: PubMed
  13. Hasegawa T, Uno H, Wei LJ. How To Summarize the Safety Profile of Epoetin Alfa Versus Best Standard of Care in Anemic Patients With Metastatic Breast Cancer Receiving Standard Chemotherapy? J Clin Oncol. 2016 Aug 09. PMID: 27507875.
    View in: PubMed
  14. Halasz LM, Uno H, Punglia RS. Reply to comparative effectiveness of stereotactic radiosurgery versus whole-brain radiation therapy for patients with brain metastases from breast or non-small cell lung cancer. Cancer. 2016 Oct 15; 122(20):3244-3245. PMID: 27391929.
    View in: PubMed
  15. Hasegawa T, Uno H, Wei LJ. Neratinib after trastuzumab in patients with HER2-positive breast cancer. Lancet Oncol. 2016 May; 17(5):e176. PMID: 27301038.
    View in: PubMed
  16. Halasz LM, Uno H, Hughes M, D'Amico T, Dexter EU, Edge SB, Hayman JA, Niland JC, Otterson GA, Pisters KM, Theriault R, Weeks JC, Punglia RS. Comparative effectiveness of stereotactic radiosurgery versus whole-brain radiation therapy for patients with brain metastases from breast or non-small cell lung cancer. Cancer. 2016 Jul 01; 122(13):2091-100. PMID: 27088755; PMCID: PMC4911286 [Available on 07/01/17].
  17. Abel GA, Cronin AM, Odejide OO, Uno H, Stone RM, Steensma DP. Influence of patient and provider characteristics on quality of care for the myelodysplastic syndromes. Br J Haematol. 2016 Jun; 173(5):713-21. PMID: 26913376.
    View in: PubMed
  18. Hasegawa T, Uno H, Wei LJ. Nivolumab in Nonsquamous Non-Small-Cell Lung Cancer. N Engl J Med. 2016 Feb 04; 374(5):492-3. PMID: 26840145.
    View in: PubMed
  19. Platz E, Lewis EF, Uno H, Peck J, Pivetta E, Merz AA, Hempel D, Wilson C, Frasure SE, Jhund PS, Cheng S, Solomon SD. Detection and prognostic value of pulmonary congestion by lung ultrasound in ambulatory heart failure patients. Eur Heart J. 2016 Apr 14; 37(15):1244-51. PMID: 26819225; PMCID: PMC5006102 [Available on 04/14/17].
  20. Brooks GA, Cronin AM, Uno H, Schrag D, Keating NL, Mack JW. Intensity of Medical Interventions between Diagnosis and Death in Patients with Advanced Lung and Colorectal Cancer: A CanCORS Analysis. J Palliat Med. 2016 Jan; 19(1):42-50. PMID: 26600474; PMCID: PMC4692113 [Available on 01/01/17].
  21. Zhao L, Claggett B, Tian L, Uno H, Pfeffer MA, Solomon SD, Trippa L, Wei LJ. On the restricted mean survival time curve in survival analysis. Biometrics. 2016 Mar; 72(1):215-21. PMID: 26302239.
    View in: PubMed
  22. Hassett MJ, Uno H, Cronin AM, Carroll NM, Hornbrook MC, Ritzwoller D. Detecting Lung and Colorectal Cancer Recurrence Using Structured Clinical/Administrative Data to Enable Outcomes Research and Population Health Management. Med Care. 2015 Jul 29. PMID: 26225443.
    View in: PubMed
  23. Uno H, Wittes J, Fu H, Solomon SD, Claggett B, Tian L, Cai T, Pfeffer MA, Evans SR, Wei LJ. Alternatives to Hazard Ratios for Comparing the Efficacy or Safety of Therapies in Noninferiority Studies. Ann Intern Med. 2015 Jul 21; 163(2):127-34. PMID: 26054047; PMCID: PMC4510023.
  24. Uno H, Tian L, Claggett B, Wei LJ. A versatile test for equality of two survival functions based on weighted differences of Kaplan-Meier curves. Stat Med. 2015 Dec 10; 34(28):3680-95. PMID: 26194988; PMCID: PMC4626406 [Available on 12/10/16].
  25. Tseng YD, Uno H, Hughes ME, Niland JC, Wong YN, Theriault R, Blitzblau RC, Moy B, Breslin T, Edge SB, Hassett MJ, Punglia RS. Biological Subtype Predicts Risk of Locoregional Recurrence After Mastectomy and Impact of Postmastectomy Radiation in a Large National Database. Int J Radiat Oncol Biol Phys. 2015 Nov 01; 93(3):622-30. PMID: 26461004.
    View in: PubMed
  26. Lam TC, Uno H, Krishnan M, Lutz S, Groff M, Cheney M, Balboni T. Adverse Outcomes After Palliative Radiation Therapy for Uncomplicated Spine Metastases: Role of Spinal Instability and Single-Fraction Radiation Therapy. Int J Radiat Oncol Biol Phys. 2015 Oct 01; 93(2):373-81. PMID: 26279324.
    View in: PubMed
  27. Uno H, Jacobson JO, Schrag D. Clinician assessment of potentially avoidable hospitalization in patients with cancer. J Clin Oncol. 2014 Oct 20; 32(30_suppl):4. PMID: 28141275.
    View in: PubMed
  28. Brooks GA, Li L, Uno H, Hassett MJ, Landon BE, Schrag D. Acute hospital care is the chief driver of regional spending variation in Medicare patients with advanced cancer. Health Aff (Millwood). 2014 Oct; 33(10):1793-800. PMID: 25288424; PMCID: PMC4203442.
  29. Uno H, Cronin AM, Wadleigh M, Schrag D, Abel GA. Derivation and validation of the SEER-Medicare myelodysplastic syndromes risk score (SMMRS). Leuk Res. 2014 Dec; 38(12):1420-4. PMID: 25443886; PMCID: PMC4314368.
  30. Tucker-Seeley RD, Abel GA, Uno H, Prigerson H. Financial hardship and the intensity of medical care received near death. Psychooncology. 2015 May; 24(5):572-8. PMID: 25052138; PMCID: PMC4305037.
  31. Weeks JC, Uno H, Taback N, Ting G, Cronin A, D'Amico TA, Friedberg JW, Schrag D. Interinstitutional variation in management decisions for treatment of 4 common types of cancer: A multi-institutional cohort study. Ann Intern Med. 2014 Jul 01; 161(1):20-30. PMID: 24979447; PMCID: PMC4479196.
  32. Uno H, Claggett B, Tian L, Inoue E, Gallo P, Miyata T, Schrag D, Takeuchi M, Uyama Y, Zhao L, Skali H, Solomon S, Jacobus S, Hughes M, Packer M, Wei LJ. Moving beyond the hazard ratio in quantifying the between-group difference in survival analysis. J Clin Oncol. 2014 Aug 01; 32(22):2380-5. PMID: 24982461; PMCID: PMC4105489.
  33. Uno H, Wei LJ, Hughes M. Effects of bracing in adolescents with idiopathic scoliosis. N Engl J Med. 2014 Feb 13; 370(7):680. PMID: 24521129.
    View in: PubMed
  34. Brooks GA, Abrams TA, Meyerhardt JA, Enzinger PC, Sommer K, Dalby CK, Uno H, Jacobson JO, Fuchs CS, Schrag D. Identification of potentially avoidable hospitalizations in patients with GI cancer. J Clin Oncol. 2014 Feb 20; 32(6):496-503. PMID: 24419123; PMCID: PMC3918534.
  35. Skali H, Lin J, Pfeffer MA, Chen CY, Cooper ME, McMurray JJ, Nissenson AR, Remuzzi G, Rossert J, Parfrey PS, Scott-Douglas NW, Singh AK, Toto R, Uno H, Ivanovich P. Hemoglobin stability in patients with anemia, CKD, and type 2 diabetes: an analysis of the TREAT (Trial to Reduce Cardiovascular Events With Aranesp Therapy) placebo arm. Am J Kidney Dis. 2013 Feb; 61(2):238-46. PMID: 23159232.
    View in: PubMed
  36. Uno H, Tian L, Cai T, Kohane IS, Wei LJ. A unified inference procedure for a class of measures to assess improvement in risk prediction systems with survival data. Stat Med. 2013 Jun 30; 32(14):2430-42. PMID: 23037800; PMCID: PMC3734387.
  37. Zhao L, Tian L, Uno H, Solomon SD, Pfeffer MA, Schindler JS, Wei LJ. Utilizing the integrated difference of two survival functions to quantify the treatment contrast for designing, monitoring, and analyzing a comparative clinical study. Clin Trials. 2012 Oct; 9(5):570-7. PMID: 22914867; PMCID: PMC3705645.
  38. Kamat A, Lyons JL, Misra V, Uno H, Morgello S, Singer EJ, Gabuzda D. Monocyte activation markers in cerebrospinal fluid associated with impaired neurocognitive testing in advanced HIV infection. J Acquir Immune Defic Syndr. 2012 Jul 01; 60(3):234-43. PMID: 22569268; PMCID: PMC3383928.
  39. Barkoudah E, Skali H, Uno H, Solomon SD, Pfeffer MA. Mortality rates in trials of subjects with type 2 diabetes. J Am Heart Assoc. 2012 Feb; 1(1):8-15. PMID: 23130114; PMCID: PMC3487314.
  40. Cesano A, Rosen DB, O'Meara P, Putta S, Gayko U, Spellmeyer DC, Cripe LD, Sun Z, Uno H, Litzow MR, Tallman MS, Paietta E. Functional pathway analysis in acute myeloid leukemia using single cell network profiling assay: effect of specimen source (bone marrow or peripheral blood) on assay readouts. Cytometry B Clin Cytom. 2012 May; 82(3):158-72. PMID: 22334473; PMCID: PMC3632455.
  41. Skali H, Parving HH, Parfrey PS, Burdmann EA, Lewis EF, Ivanovich P, Keithi-Reddy SR, McGill JB, McMurray JJ, Singh AK, Solomon SD, Uno H, Pfeffer MA. Stroke in patients with type 2 diabetes mellitus, chronic kidney disease, and anemia treated with Darbepoetin Alfa: the trial to reduce cardiovascular events with Aranesp therapy (TREAT) experience. Circulation. 2011 Dec 20; 124(25):2903-8. PMID: 22104547.
    View in: PubMed
  42. McMurray JJ, Uno H, Jarolim P, Desai AS, de Zeeuw D, Eckardt KU, Ivanovich P, Levey AS, Lewis EF, McGill JB, Parfrey P, Parving HH, Toto RM, Solomon SD, Pfeffer MA. Predictors of fatal and nonfatal cardiovascular events in patients with type 2 diabetes mellitus, chronic kidney disease, and anemia: an analysis of the Trial to Reduce cardiovascular Events with Aranesp (darbepoetin-alfa) Therapy (TREAT). Am Heart J. 2011 Oct; 162(4):748-755.e3. PMID: 21982669.
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  43. Jacobus SJ, Kumar S, Uno H, Van Wier SA, Ahmann GJ, Henderson KJ, Callander NS, Williams ME, Siegel DS, Greipp PR, Rajkumar SV, Fonseca R. Impact of high-risk classification by FISH: an eastern cooperative oncology group (ECOG) study E4A03. Br J Haematol. 2011 Nov; 155(3):340-8. PMID: 21902684; PMCID: PMC3192237.
  44. Kumar SK, Uno H, Jacobus SJ, Van Wier SA, Ahmann GJ, Henderson KJ, Callander NS, Haug JL, Siegel DS, Greipp PR, Fonseca R, Rajkumar SV. Impact of gene expression profiling-based risk stratification in patients with myeloma receiving initial therapy with lenalidomide and dexamethasone. Blood. 2011 Oct 20; 118(16):4359-62. PMID: 21860025; PMCID: PMC3204907.
  45. Lyons JL, Uno H, Ancuta P, Kamat A, Moore DJ, Singer EJ, Morgello S, Gabuzda D. Plasma sCD14 is a biomarker associated with impaired neurocognitive test performance in attention and learning domains in HIV infection. J Acquir Immune Defic Syndr. 2011 Aug 15; 57(5):371-9. PMID: 21646912; PMCID: PMC3159710.
  46. Skali H, Uno H, Levey AS, Inker LA, Pfeffer MA, Solomon SD. Prognostic assessment of estimated glomerular filtration rate by the new Chronic Kidney Disease Epidemiology Collaboration equation in comparison with the Modification of Diet in Renal Disease Study equation. Am Heart J. 2011 Sep; 162(3):548-54. PMID: 21884875.
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  47. Desai AS, Toto R, Jarolim P, Uno H, Eckardt KU, Kewalramani R, Levey AS, Lewis EF, McMurray JJ, Parving HH, Solomon SD, Pfeffer MA. Association between cardiac biomarkers and the development of ESRD in patients with type 2 diabetes mellitus, anemia, and CKD. Am J Kidney Dis. 2011 Nov; 58(5):717-28. PMID: 21820220.
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  48. Pouleur AC, Uno H, Prescott MF, Desai A, Appelbaum E, Lukashevich V, Smith BA, Dahlöf B, Solomon SD. Suppression of aldosterone mediates regression of left ventricular hypertrophy in patients with hypertension. J Renin Angiotensin Aldosterone Syst. 2011 Dec; 12(4):483-90. PMID: 21746765.
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  49. Pouleur AC, Knappe D, Shah AM, Uno H, Bourgoun M, Foster E, McNitt S, Hall WJ, Zareba W, Goldenberg I, Moss AJ, Pfeffer MA, Solomon SD. Relationship between improvement in left ventricular dyssynchrony and contractile function and clinical outcome with cardiac resynchronization therapy: the MADIT-CRT trial. Eur Heart J. 2011 Jul; 32(14):1720-9. PMID: 21609974.
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  50. Ye S, Grunnert M, Thune JJ, Stephenson KM, Uno H, Finn PV, McMurray JJ, Velazquez EJ, Califf R, Pfeffer MA, Solomon SD. Circumstances and outcomes of sudden unexpected death in patients with high-risk myocardial infarction: implications for prevention. Circulation. 2011 Jun 14; 123(23):2674-80. PMID: 21606398.
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  51. Knappe D, Pouleur AC, Shah AM, Cheng S, Uno H, Hall WJ, Bourgoun M, Foster E, Zareba W, Goldenberg I, McNitt S, Pfeffer MA, Moss AJ, Solomon SD. Dyssynchrony, contractile function, and response to cardiac resynchronization therapy. Circ Heart Fail. 2011 Jul; 4(4):433-40. PMID: 21602574.
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  52. Campagnaro EL, Jacobus SJ, Uno H, Oken MM, Kyle RA, Rajkumar SV, Greipp PR, Vesole DH, Weiss M, Fonseca R, Lazarus HM. Survival outcomes in elderly patients with plasma cell myeloma: The three-decade Eastern Cooperative Oncology Group (ECOG) experience. J Clin Oncol. 2011 May 20; 29(15_suppl):8021. PMID: 28022965.
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  53. Uno H, Cai T, Tian L, Wei LJ. Graphical procedures for evaluating overall and subject-specific incremental values from new predictors with censored event time data. Biometrics. 2011 Dec; 67(4):1389-96. PMID: 21504421; PMCID: PMC3144297.
  54. Vardeny O, Uno H, Braunwald E, Rouleau JL, Gersh B, Maggioni AP, Domanski M, Pfeffer MA, Solomon SD. Opposing effects of ß blockers and angiotensin-converting enzyme inhibitors on development of new-onset diabetes mellitus in patients with stable coronary artery disease. Am J Cardiol. 2011 Jun 15; 107(12):1705-9. PMID: 21507365; PMCID: PMC3109120.
  55. Shimada T, Oda S, Sadahiro T, Nakamura M, Hirayama Y, Watanabe E, Abe R, Nakada TA, Tateishi Y, Otani S, Hirasawa H, Tokuhisa T, Uno H. Outcome prediction in sepsis combined use of genetic polymorphisms - A study in Japanese population. Cytokine. 2011 Apr; 54(1):79-84. PMID: 21282064.
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  56. Uno H, Cai T, Pencina MJ, D'Agostino RB, Wei LJ. On the C-statistics for evaluating overall adequacy of risk prediction procedures with censored survival data. Stat Med. 2011 May 10; 30(10):1105-17. PMID: 21484848; PMCID: PMC3079915.
  57. Lewis EF, Pfeffer MA, Feng A, Uno H, McMurray JJ, Toto R, Gandra SR, Solomon SD, Moustafa M, Macdougall IC, Locatelli F, Parfrey PS. Darbepoetin alfa impact on health status in diabetes patients with kidney disease: a randomized trial. Clin J Am Soc Nephrol. 2011 Apr; 6(4):845-55. PMID: 21212421; PMCID: PMC3069378.
  58. Hung CL, Verma A, Uno H, Shin SH, Bourgoun M, Hassanein AH, McMurray JJ, Velazquez EJ, Kober L, Pfeffer MA, Solomon SD. Longitudinal and circumferential strain rate, left ventricular remodeling, and prognosis after myocardial infarction. J Am Coll Cardiol. 2010 Nov 23; 56(22):1812-22. PMID: 21087709.
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  59. Shah AM, Uno H, Køber L, Velazquez EJ, Maggioni AP, MacDonald MR, Petrie MC, McMurray JJ, Califf RM, Pfeffer MA, Solomon SD. The inter-relationship of diabetes and left ventricular systolic function on outcome after high-risk myocardial infarction. Eur J Heart Fail. 2010 Nov; 12(11):1229-37. PMID: 20965879.
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  60. Solomon SD, Uno H, Lewis EF, Eckardt KU, Lin J, Burdmann EA, de Zeeuw D, Ivanovich P, Levey AS, Parfrey P, Remuzzi G, Singh AK, Toto R, Huang F, Rossert J, McMurray JJ, Pfeffer MA. Erythropoietic response and outcomes in kidney disease and type 2 diabetes. N Engl J Med. 2010 Sep 16; 363(12):1146-55. PMID: 20843249.
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  61. Cripe LD, Uno H, Paietta EM, Litzow MR, Ketterling RP, Bennett JM, Rowe JM, Lazarus HM, Luger S, Tallman MS. Zosuquidar, a novel modulator of P-glycoprotein, does not improve the outcome of older patients with newly diagnosed acute myeloid leukemia: a randomized, placebo-controlled trial of the Eastern Cooperative Oncology Group 3999. Blood. 2010 Nov 18; 116(20):4077-85. PMID: 20716770; PMCID: PMC2993615.
  62. Pouleur AC, Barkoudah E, Uno H, Skali H, Finn PV, Zelenkofske SL, Belenkov YN, Mareev V, Velazquez EJ, Rouleau JL, Maggioni AP, Køber L, Califf RM, McMurray JJ, Pfeffer MA, Solomon SD. Pathogenesis of sudden unexpected death in a clinical trial of patients with myocardial infarction and left ventricular dysfunction, heart failure, or both. Circulation. 2010 Aug 10; 122(6):597-602. PMID: 20660803.
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  63. Nagata T, Uno H, Perry MJ. Clinical consequences of road traffic injuries among the elderly in Japan. BMC Public Health. 2010 Jun 28; 10:375. PMID: 20584283; PMCID: PMC2903521.
  64. Cai T, Tian L, Uno H, Solomon SD, Wei LJ. Calibrating parametric subject-specific risk estimation. Biometrika. 2010 Jun; 97(2):389-404. PMID: 23049123.
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  65. Shin SH, Hung CL, Uno H, Hassanein AH, Verma A, Bourgoun M, Køber L, Ghali JK, Velazquez EJ, Califf RM, Pfeffer MA, Solomon SD. Mechanical dyssynchrony after myocardial infarction in patients with left ventricular dysfunction, heart failure, or both. Circulation. 2010 Mar 09; 121(9):1096-103. PMID: 20176989.
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  66. Richardson PG, Soiffer RJ, Antin JH, Uno H, Jin Z, Kurtzberg J, Martin PL, Steinbach G, Murray KF, Vogelsang GB, Chen AR, Krishnan A, Kernan NA, Avigan DE, Spitzer TR, Shulman HM, Di Salvo DN, Revta C, Warren D, Momtaz P, Bradwin G, Wei LJ, Iacobelli M, McDonald GB, Guinan EC. Defibrotide for the treatment of severe hepatic veno-occlusive disease and multiorgan failure after stem cell transplantation: a multicenter, randomized, dose-finding trial. Biol Blood Marrow Transplant. 2010 Jul; 16(7):1005-17. PMID: 20167278; PMCID: PMC2956581.
  67. Li L, Evans SR, Uno H, Wei LJ. Predicted Interval Plots (PIPS): A Graphical Tool for Data Monitoring of Clinical Trials. Stat Biopharm Res. 2009 Nov 01; 1(4):348-355. PMID: 21423789.
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  68. Gertz MA, Abonour R, Heffner LT, Greipp PR, Uno H, Rajkumar SV. Clinical value of minor responses after 4 doses of rituximab in Waldenström macroglobulinaemia: a follow-up of the Eastern Cooperative Oncology Group E3A98 trial. Br J Haematol. 2009 Dec; 147(5):677-80. PMID: 19751237; PMCID: PMC3548235.
  69. Pfeffer MA, Burdmann EA, Chen CY, Cooper ME, de Zeeuw D, Eckardt KU, Ivanovich P, Kewalramani R, Levey AS, Lewis EF, McGill J, McMurray JJ, Parfrey P, Parving HH, Remuzzi G, Singh AK, Solomon SD, Toto R, Uno H. Baseline characteristics in the Trial to Reduce Cardiovascular Events With Aranesp Therapy (TREAT). Am J Kidney Dis. 2009 Jul; 54(1):59-69. PMID: 19501439.
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  70. Gertz MA, Abonour R, Heffner LT, Greipp PR, Uno H, Rajkumar SV. Long-lasting responses after four doses of rituximab in Waldenström's macroglobulinemia: Clinical value of minor responses: A follow-up of the Eastern Cooperative Oncology Group E3A98 trial. J Clin Oncol. 2009 May 20; 27(15_suppl):8513. PMID: 27960876.
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  71. Meris A, Amigoni M, Uno H, Thune JJ, Verma A, Køber L, Bourgoun M, McMurray JJ, Velazquez EJ, Maggioni AP, Ghali J, Arnold JM, Zelenkofske S, Pfeffer MA, Solomon SD. Left atrial remodelling in patients with myocardial infarction complicated by heart failure, left ventricular dysfunction, or both: the VALIANT Echo study. Eur Heart J. 2009 Jan; 30(1):56-65. PMID: 19001474.
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  72. Sasamura H, Nakaya H, Julius S, Takebayashi T, Sato Y, Uno H, Takeuchi M, Ishiguro K, Murakami M, Ryuzaki M, Itoh H. The short treatment with the angiotensin receptor blocker candesartan surveyed by telemedicine (STAR CAST) study: rationale and study design. Hypertens Res. 2008 Oct; 31(10):1843-9. PMID: 19015590.
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  73. Tsushima Y, Tateishi U, Uno H, Takeuchi M, Terauchi T, Goya T, Kim EE. Diagnostic performance of PET/CT in differentiation of malignant and benign non-solid solitary pulmonary nodules. Ann Nucl Med. 2008 Aug; 22(7):571-7. PMID: 18756359.
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  74. Yonemori K, Katsumata N, Noda A, Uno H, Yunokawa M, Nakano E, Kouno T, Shimizu C, Ando M, Tamura K, Takeuchi M, Fujiwara Y. Development and verification of a prediction model using serum tumor markers to predict the response to chemotherapy of patients with metastatic or recurrent breast cancer. J Cancer Res Clin Oncol. 2008 Nov; 134(11):1199-206. PMID: 18528707.
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  75. Hashimoto K, Yonemori K, Katsumata N, Hotchi M, Uno H, Kouno T, Shimizu C, Tamura K, Ando M, Takeuchi M, Fujiwara Y. Which factors will make the duration short between last palliative chemotherapy and death? J Clin Oncol. 2008 May 20; 26(15_suppl):20575. PMID: 27949646.
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  76. Yonemori K, Tateishi U, Uno H, Yonemori Y, Tsuta K, Takeuchi M, Matsuno Y, Fujiwara Y, Asamura H, Kusumoto M. Development and validation of diagnostic prediction model for solitary pulmonary nodules. Respirology. 2007 Nov; 12(6):856-62. PMID: 17986114.
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  77. Yonemori K, Yamaguchi U, Kaneko M, Uno H, Takeuchi M, Ando M, Fujiwara Y, Hosono A, Makimoto A, Hasegawa T, Yokoyama R, Nakatani F, Kawai A, Beppu Y, Chuman H. Prediction of response and prognostic factors for Ewing family of tumors in a low incidence population. J Cancer Res Clin Oncol. 2008 Mar; 134(3):389-95. PMID: 17687565.
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  78. Yonemori K, Tateishi U, Tsuta K, Yonemori Y, Uno H, Asamura H, Kusumoto M. Solitary pulmonary granuloma caused by Mycobacterium avium-intracellulare complex. Int J Tuberc Lung Dis. 2007 Feb; 11(2):215-21. PMID: 17263294.
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  79. Matsui S, Ito M, Nishiyama H, Uno H, Kotani H, Watanabe J, Guilford P, Reeve A, Fukushima M, Ogawa O. Genomic characterization of multiple clinical phenotypes of cancer using multivariate linear regression models. Bioinformatics. 2007 Mar 15; 23(6):732-8. PMID: 17237045.
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  80. Yonemori K, Katsumata N, Kaneko M, Uno H, Matsumoto K, Kouno T, Shimizu C, Ando M, Takeuchi M, Fujiwara Y. Prediction of response to repeat utilization of anthracycline in recurrent breast cancer patients previously administered anthracycline-containing chemotherapeutic regimens as neoadjuvant or adjuvant chemotherapy. Breast Cancer Res Treat. 2007 Jul; 103(3):313-8. PMID: 17063267.
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  81. Yonemori K, Tsuta K, Tateishi U, Uno H, Asamura H, Matsuno Y, Kusumoto M. Diagnostic accuracy of CT-guided percutaneous cutting needle biopsy for thymic tumours. Clin Radiol. 2006 Sep; 61(9):771-5. PMID: 16905385.
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  82. Tateishi U, Uno H, Yonemori K, Satake M, Takeuchi M, Arai Y. Prediction of lung adenocarcinoma without vessel invasion: a CT scan volumetric analysis. Chest. 2005 Nov; 128(5):3276-83. PMID: 16304272.
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  83. Yonemori K, Katsumata N, Uno H, Matsumoto K, Kouno T, Tokunaga S, Yamanaka Y, Shimizu C, Ando M, Takeuchi M, Fujiwara Y. Efficacy of weekly paclitaxel in patients with docetaxel-resistant metastatic breast cancer. Breast Cancer Res Treat. 2005 Feb; 89(3):237-41. PMID: 15754121.
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  84. Okanoya K, Ikebuchi M, Uno H, Watanabe S. Left-side dominance for song discrimination in Bengalese finches (Lonchura striata var. domestica). Anim Cogn. 2001 Nov; 4(3-4):241-5. PMID: 24777514.
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  85. Schenkel AR, Uno H, Pauza CD. Asymptomatic simian immunodeficiency virus infection decreases blood CD4(+) T cells by accumulating recirculating lymphocytes in the lymphoid tissues. J Virol. 1999 Jan; 73(1):601-7. PMID: 9847365; PMCID: PMC103866.
  86. Matsuoka H, Uno H, Kawano K, Tsuda K, Tsubouchi H. MHC class II restriction for T cell proliferative response to mite antigen. Ann Allergy Asthma Immunol. 1996 Sep; 77(3):191-6. PMID: 8814043.
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  87. Shimizu M, Uno H, Ito T, Masuda Y, Kurokawa M. [Research and development of zonisamide, a new type of antiepileptic drug]. Yakugaku Zasshi. 1996 Jul; 116(7):533-47. PMID: 8831258.
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  88. Scharko AM, Perlman SB, Hanson JM, Uno H, Pauza CD. Whole body positron emission tomography imaging of simian immunodeficiency virus-infected rhesus macaques. Proc Natl Acad Sci U S A. 1996 Jun 25; 93(13):6425-30. PMID: 8692831; PMCID: PMC39039.
  89. Uno H, Matsuoka H, Suzuki M, Tsuda K, Tsubouchi H. Altered expression of class I HLA antigen on peripheral mononuclear cells in patients with adult T-cell leukemia: inverse relationship with natural killer susceptibility. Cancer Epidemiol Biomarkers Prev. 1995 Jun; 4(4):367-72. PMID: 7655332.
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  90. Toyama T, Uno H, Yamashita K, Kubuki Y, Suzuki M, Maeda K, Matsuoka H, Tsubouchi H. [Study on prognostic factors in twenty-five patients with myelodysplastic syndrome]. Gan To Kagaku Ryoho. 1995 Feb; 22(2):227-32. PMID: 7857097.
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  91. Pauza CD, Emau P, Salvato MS, Trivedi P, MacKenzie D, Malkovsky M, Uno H, Schultz KT. Pathogenesis of SIVmac251 after atraumatic inoculation of the rectal mucosa in rhesus monkeys. J Med Primatol. 1993 Feb-May; 22(2-3):154-61. PMID: 8411107.
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  92. Sun DY, Guo JZ, Hartmann HA, Uno H, Hokin LE. Differential expression of the alpha 2 and beta messenger RNAs of Na,K-ATPase in developing brine shrimp as measured by in situ hybridization. J Histochem Cytochem. 1992 Apr; 40(4):555-62. PMID: 1313064.
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  93. Sun DY, Guo JZ, Hartmann HA, Uno H, Hokin LE. Na,K-ATPase expression in the developing brine shrimp Artemia. Immunochemical localization of the alpha- and beta-subunits. J Histochem Cytochem. 1991 Nov; 39(11):1455-60. PMID: 1655875.
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  94. Kurokawa M, Sato F, Masuda Y, Yoshida T, Ochi Y, Zushi K, Fujiwara I, Naruto S, Uno H, Matsumoto J. Synthesis and biological activity of 11-[4-(cinnamyl)-1-piperazinyl]- 6,11-dihydrodibenz[b,e]oxepin derivatives, potential agents for the treatment of cerebrovascular disorders. Chem Pharm Bull (Tokyo). 1991 Oct; 39(10):2564-73. PMID: 1806275.
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  95. Kurokawa M, Sato F, Fujiwara I, Hatano N, Honda Y, Yoshida T, Naruto S, Mastumoto J, Uno H. A new class of calcium antagonists. 2. Synthesis and biological activity of 11-[[4-[4-(4-fluorophenyl)-1-piperazinyl]butyryl]amino]-6,11- dihydrodibenzo[b,e]-thiepin maleate and related compounds. J Med Chem. 1991 Mar; 34(3):927-34. PMID: 2002473.
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  96. Kurokawa M, Sato F, Hatano N, Honda Y, Uno H. A new class of calcium antagonists. Synthesis and biological activity of 11-[(omega-aminoalkanoyl)amino]-6,6a,7,8,9,10,10a,11-octahydrodibenzo [b,e]thiepin derivatives. J Med Chem. 1991 Feb; 34(2):593-9. PMID: 1995882.
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  97. Uno H, Lohmiller L, Thieme C, Kemnitz JW, Engle MJ, Roecker EB, Farrell PM. Brain damage induced by prenatal exposure to dexamethasone in fetal rhesus macaques. I. Hippocampus. Brain Res Dev Brain Res. 1990 May 01; 53(2):157-67. PMID: 2357788.
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  98. Kurokawa M, Uno H, Nakamura H, Sato F, Naruto S. Synthesis and antiinflammatory activity of cis- and trans-6,6a,7,8,9,10,10a,11-octahydro-11-oxodibenzo[b,e]thiepinacetic and -oxepinacetic acids. J Med Chem. 1990 Feb; 33(2):504-9. PMID: 2299620.
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  99. Nishikawa Y, Shindo T, Ishii K, Nakamura H, Kon T, Uno H. Acrylamide derivatives as antiallergic agents. 2. Synthesis and structure-activity relationships of N-[4-[4-(diphenylmethyl)-1-piperazinyl]butyl]-3-(3-pyridyl)acryl amides. J Med Chem. 1989 Mar; 32(3):583-93. PMID: 2465410.
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  100. Hino K, Nagai Y, Uno H, Masuda Y, Oka M, Karasawa T. A novel class of potential central nervous system agents. 3-Phenyl-2-(1-piperazinyl)-5H-1-benzazepines. J Med Chem. 1988 Jan; 31(1):107-17. PMID: 2891853.
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  101. Natsuka K, Nakamura H, Nishikawa Y, Negoro T, Uno H, Nishimura H. Synthesis and structure-activity relationships of 1-substituted 4-(1,2-diphenylethyl)piperazine derivatives having narcotic agonist and antagonist activity. J Med Chem. 1987 Oct; 30(10):1779-87. PMID: 3656354.
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  102. Uno H. The stumptailed macaque as a model for baldness: effects of minoxidil. Int J Cosmet Sci. 1986 Apr; 8(2):63-71. PMID: 19460042.
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  103. Warner TF, Uno H, Hafez GR, Burgess J, Bolles C, Lloyd RV, Oka M. Merkel cells and Merkel cell tumors. Ultrastructure, immunocytochemistry and review of the literature. Cancer. 1983 Jul 15; 52(2):238-45. PMID: 6344978.
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