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Rajeev Malhotra, M.D.

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Research
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. R01HL159514 (LEWIS, GREGORY DYER) Aug 15, 2021 - Jun 30, 2025
    NIH
    Characterization of Functional Iron Deficiency and Repletion in Heart Failure with Preserved Ejection Fraction
    Role: Co-Principal Investigator
  2. R01HL142809 (MALHOTRA, RAJEEV) Aug 10, 2018 - May 31, 2023
    NIH
    The Role of Histone Deacetylase 9 in Vascular Calcification
    Role: Principal Investigator
  3. 3R01HL142809-03S1 (MALHOTRA, RAJEEV) Aug 10, 2018 - May 30, 2023
    NIH
    The Role of Histone Deacetylase 9 in Vascular Calcification
    Role: Principal Investigator
  4. 18TPA34230025 (MALHOTRA, RAJEEV) Jul 1, 2018 - Jun 30, 2021
    American Heart Association Transformational Award
    A Novel Regulatory Pathway in Vascular Smooth Muscle Phenotypic Transition and Calcification
    Role: Principal Investigator
  5. K08HL111210 (MALHOTRA, RAJEEV) Feb 1, 2014 - Aug 31, 2019
    NIH
    The Role of Bone Morphogenetic Proteins in Vascular Calcification
    Role: Principal Investigator

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Signori D, Magliocca A, Hayashida K, Graw JA, Malhotra R, Bellani G, Berra L, Rezoagli E. Inhaled nitric oxide: role in the pathophysiology of cardio-cerebrovascular and respiratory diseases. Intensive Care Med Exp. 2022 Jun 27; 10(1):28. PMID: 35754072; PMCID: PMC9234017.
    Citations:    
  2. Nayor M, Chernofsky A, Miller PE, Spartano NL, Murthy VL, Malhotra R, Houstis NE, Murabito JM, Clish CB, Larson MG, Vasan RS, Shah RV, Lewis GD. Integrative Analysis of Circulating Metabolite Levels That Correlate With Physical Activity and Cardiorespiratory Fitness. Circ Genom Precis Med. 2022 06; 15(3):e003592. PMID: 35536222; PMCID: PMC9233103.
    Citations:    Fields:    Translation:Humans
  3. Wen W, Portales-Castillo I, Seethapathy R, Krinsky S, Kroshinsky D, Kalim S, Goverman J, Nazarian RM, Chitalia V, Malhotra R, Kramann R, Malhotra CK, Nigwekar SU. Intravenous sodium thiosulphate for vascular calcification of hemodialysis patients - a systematic review and meta-analysis. Nephrol Dial Transplant. 2022 May 06. PMID: 35521751.
    Citations:    Fields:    
  4. Namasivayam M, Lau ES, Zern EK, Schoenike MW, Hardin KM, Sbarbaro JA, Cunningham TF, Farrell RM, Rouvina J, Kowal A, Bhat RR, Brooks LC, Nayor M, Shah RV, Ho JE, Malhotra R, Lewis GD. Exercise Blood Pressure in Heart Failure With Preserved and Reduced Ejection Fraction. JACC Heart Fail. 2022 04; 10(4):278-286. PMID: 35361448.
    Citations:    Fields:    Translation:Humans
  5. Tian W, Cui L, Nicholson CJ, Malhotra R. Successful retrieval of an entrapped and uncoiled guide wire using a wire-cutting technique. Cardiovasc J Afr. 2022 May-Jun 23; 33(3):162-164. PMID: 35265957.
    Citations:    Fields:    
  6. Mohta M, Chilkoti GT, Malhotra RK, R L. Reply to: phenylephrine and norepinephrine for the management of spinal-induced hypotension in preeclamptic patients. Eur J Anaesthesiol. 2022 03 01; 39(3):292. PMID: 35115463.
    Citations:    Fields:    Translation:Humans
  7. Kulpanowski AM, Copen WA, Hancock BL, Rosenthal ES, Schoenfeld DA, Dodelson JA, Edlow BL, Kimberly WT, Amorim E, Westover MB, Ning MM, Schaefer PW, Malhotra R, Giacino JT, Greer DM, Wu O. Severe cerebral edema in substance-related cardiac arrest patients. Resuscitation. 2022 04; 173:103-111. PMID: 35149137; PMCID: PMC9282938.
    Citations:    Fields:    Translation:Humans
  8. Redaelli S, Magliocca A, Malhotra R, Ristagno G, Citerio G, Bellani G, Berra L, Rezoagli E. Nitric oxide: Clinical applications in critically ill patients. Nitric Oxide. 2022 04 01; 121:20-33. PMID: 35123061.
    Citations: 2     Fields:    Translation:HumansCells
  9. Traeger L, Wiegand SB, Sauer AJ, Corman BHP, Peneyra KM, Wunderer F, Fischbach A, Bagchi A, Malhotra R, Zapol WM, Bloch DB. UBA6 and NDFIP1 regulate the degradation of ferroportin. Haematologica. 2022 02 01; 107(2):478-488. PMID: 34320783; PMCID: PMC8804582.
    Citations: 1     Fields:    Translation:HumansAnimalsCells
  10. Lau ES, Panah LG, Zern EK, Liu EE, Farrell R, Schoenike MW, Namasivayam M, Churchill TW, Curreri L, Malhotra R, Nayor M, Lewis GD, Ho JE. Arterial Stiffness and Vascular Load in HFpEF: Differences Among Women and Men. J Card Fail. 2022 02; 28(2):202-211. PMID: 34955334; PMCID: PMC8840989.
    Citations:    Fields:    Translation:Humans
  11. Malhotra R, Nicholson CJ, Wang D, Bhambhani V, Paniagua S, Slocum C, Sigurslid HH, Lino Cardenas CL, Li R, Boerboom SL, Chen YC, Hwang SJ, Yao C, Ichinose F, Bloch DB, Lindsay ME, Lewis GD, Aragam JR, Hoffmann U, Mitchell GF, Hamburg NM, Vasan RS, Benjamin EJ, Larson MG, Zapol WM, Cheng S, Roh JD, O'Donnell CJ, Nguyen C, Levy D, Ho JE. Matrix Gla Protein Levels Are Associated With Arterial Stiffness and Incident Heart Failure With Preserved Ejection Fraction. Arterioscler Thromb Vasc Biol. 2022 02; 42(2):e61-e73. PMID: 34809448; PMCID: PMC8792238.
    Citations: 2     Fields:    Translation:HumansAnimals
  12. Nayor M, Chernofsky A, Spartano NL, Tanguay M, Blodgett JB, Murthy VL, Malhotra R, Houstis NE, Velagaleti RS, Murabito JM, Larson MG, Vasan RS, Shah RV, Lewis GD. Physical activity and fitness in the community: the Framingham Heart Study. Eur Heart J. 2021 11 21; 42(44):4565-4575. PMID: 34436560; PMCID: PMC8633734.
    Citations: 2     Fields:    Translation:Humans
  13. Börner K, Teichmann SA, Quardokus EM, Gee JC, Browne K, Osumi-Sutherland D, Herr BW, Bueckle A, Paul H, Haniffa M, Jardine L, Bernard A, Ding SL, Miller JA, Lin S, Halushka MK, Boppana A, Longacre TA, Hickey J, Lin Y, Valerius MT, He Y, Pryhuber G, Sun X, Jorgensen M, Radtke AJ, Wasserfall C, Ginty F, Ho J, Sunshine J, Beuschel RT, Brusko M, Lee S, Malhotra R, Jain S, Weber G. Anatomical structures, cell types and biomarkers of the Human Reference Atlas. Nat Cell Biol. 2021 11; 23(11):1117-1128. PMID: 34750582.
    Citations: 3     Fields:    Translation:HumansCells
  14. Aguilar-Pineda JA, Albaghdadi M, Jiang W, Vera-Lopez KJ, Nieto-Montesinos R, Alvarez KLF, Davila Del-Carpio G, Gómez B, Lindsay ME, Malhotra R, Lino Cardenas CL. Structural and Functional Analysis of Female Sex Hormones against SARS-CoV-2 Cell Entry. Int J Mol Sci. 2021 Oct 26; 22(21). PMID: 34768939.
    Citations: 6     Fields:    Translation:HumansAnimalsCells
  15. Aguilar-Pineda JA, Vera-Lopez KJ, Shrivastava P, Chávez-Fumagalli MA, Nieto-Montesinos R, Alvarez-Fernandez KL, Goyzueta Mamani LD, Davila Del-Carpio G, Gomez-Valdez B, Miller CL, Malhotra R, Lindsay ME, Lino Cardenas CL. Vascular smooth muscle cell dysfunction contribute to neuroinflammation and Tau hyperphosphorylation in Alzheimer disease. iScience. 2021 Sep 24; 24(9):102993. PMID: 34505007; PMCID: PMC8417400.
    Citations: 3     
  16. Nayor M, Shah RV, Tanguay M, Blodgett JB, Chernofsky A, Miller PE, Xanthakis V, Malhotra R, Houstis NE, Velagaleti RS, Larson MG, Vasan RS, Lewis GD. Feasibility, Methodology, and Interpretation of Broad-Scale Assessment of Cardiorespiratory Fitness in a Large Community-Based Sample. Am J Cardiol. 2021 10 15; 157:56-63. PMID: 34391575; PMCID: PMC9252421.
    Citations:    Fields:    Translation:Humans
  17. Shah RV, Schoenike MW, Armengol de la Hoz MÁ, Cunningham TF, Blodgett JB, Tanguay M, Sbarbaro JA, Nayor M, Rouvina J, Kowal A, Houstis N, Baggish AL, Ho JE, Hardin C, Malhotra R, Larson MG, Vasan RS, Lewis GD. Metabolic Cost of Exercise Initiation in Patients With Heart Failure With Preserved Ejection Fraction vs Community-Dwelling Adults. JAMA Cardiol. 2021 06 01; 6(6):653-660. PMID: 33729454; PMCID: PMC7970388.
    Citations: 3     Fields:    Translation:Humans
  18. Chen L, Luo S, Dupre A, Vasoya RP, Parthasarathy A, Aita R, Malhotra R, Hur J, Toke NH, Chiles E, Yang M, Cao W, Flores J, Ellison CE, Gao N, Sahota A, Su X, Bonder EM, Verzi MP. The nuclear receptor HNF4 drives a brush border gene program conserved across murine intestine, kidney, and embryonic yolk sac. Nat Commun. 2021 05 17; 12(1):2886. PMID: 34001900; PMCID: PMC8129143.
    Citations: 3     Fields:    Translation:HumansAnimalsCells
  19. McNeill JN, Lau ES, Zern EK, Nayor M, Malhotra R, Liu EE, Bhat RR, Brooks LC, Farrell R, Sbarbaro JA, Schoenike MW, Medoff BD, Lewis GD, Ho JE. Association of obesity-related inflammatory pathways with lung function and exercise capacity. Respir Med. 2021 07; 183:106434. PMID: 33964816; PMCID: PMC8144063.
    Citations: 1     Fields:    Translation:HumansCells
  20. Grange RMH, Sharma R, Shah H, Reinstadler B, Goldberger O, Cooper MK, Nakagawa A, Miyazaki Y, Hindle AG, Batten AJ, Wojtkiewicz GR, Schleifer G, Bagchi A, Marutani E, Malhotra R, Bloch DB, Ichinose F, Mootha VK, Zapol WM. Hypoxia ameliorates brain hyperoxia and NAD+ deficiency in a murine model of Leigh syndrome. Mol Genet Metab. 2021 05; 133(1):83-93. PMID: 33752971; PMCID: PMC8489256.
    Citations: 6     Fields:    Translation:HumansAnimalsCells
  21. Zern EK, Ho JE, Panah LG, Lau ES, Liu E, Farrell R, Sbarbaro JA, Schoenike MW, Pappagianopoulos PP, Namasivayam M, Malhotra R, Nayor M, Lewis GD. Exercise Intolerance in Heart Failure With Preserved Ejection Fraction: Arterial Stiffness and Aabnormal Left Ventricular Hemodynamic Responses During Exercise. J Card Fail. 2021 06; 27(6):625-634. PMID: 33647476; PMCID: PMC8180488.
    Citations: 2     Fields:    Translation:Humans
  22. Nicholson CJ, Wooster L, Sigurslid HH, Li RH, Jiang W, Tian W, Lino Cardenas CL, Malhotra R. Estimating risk of mechanical ventilation and in-hospital mortality among adult COVID-19 patients admitted to Mass General Brigham: The VICE and DICE scores. EClinicalMedicine. 2021 Mar; 33:100765. PMID: 33655204; PMCID: PMC7906522.
    Citations: 32     
  23. Nakajima A, Araki M, Kurihara O, Minami Y, Soeda T, Yonetsu T, Higuma T, Kakuta T, McNulty I, Lee H, Malhotra R, Nakamura S, Jang IK. Predictors for Rapid Progression of Coronary Calcification: An Optical Coherence Tomography Study. J Am Heart Assoc. 2021 02 02; 10(3):e019235. PMID: 33496191; PMCID: PMC7955445.
    Citations: 4     Fields:    Translation:Humans
  24. Churchill TW, Li SX, Curreri L, Zern EK, Lau ES, Liu EE, Farrell R, Shoenike MW, Sbarbaro J, Malhotra R, Nayor M, Tschöpe C, de Boer RA, Lewis GD, Ho JE. Evaluation of 2 Existing Diagnostic Scores for Heart Failure With Preserved Ejection Fraction Against a Comprehensively Phenotyped Cohort. Circulation. 2021 01 19; 143(3):289-291. PMID: 33464963; PMCID: PMC8059354.
    Citations: 2     Fields:    Translation:Humans
  25. Malhotra R, Namasivayam M, Ghoshhajra BB, Passeri JJ, Hoenig PA, Stone JR. Case 36-2020: A 72-Year-Old Woman with Dark Urine and Weakness. N Engl J Med. 2020 Nov 19; 383(21):2066-2076. PMID: 33207098.
    Citations:    Fields:    Translation:Humans
  26. Bhat RR, Schoenike MW, Kowal A, White C, Rouvina J, Hardin CC, Malhotra R, Lewis GD. Feasibility and Consistency of Results with Deployment of an In-Line Filter for Exercise-Based Evaluations of Patients With Heart Failure During the Novel Coronavirus Disease-2019 Pandemic. J Card Fail. 2021 01; 27(1):105-108. PMID: 33098974.
    Citations:    Fields:    Translation:HumansPHPublic Health
  27. Nicholson CJ, Wooster L, Sigurslid HH, Li RF, Jiang W, Tian W, Cardenas CLL, Malhotra R. Estimating Risk of Mechanical Ventilation and Mortality Among Adult COVID-19 patients Admitted to Mass General Brigham: The VICE and DICE Scores. medRxiv. 2020 Sep 16. PMID: 32995802; PMCID: PMC7523141.
    Citations: 4     
  28. Nayor M, Shah RV, Miller PE, Blodgett JB, Tanguay M, Pico AR, Murthy VL, Malhotra R, Houstis NE, Deik A, Pierce KA, Bullock K, Dailey L, Velagaleti RS, Moore SA, Ho JE, Baggish AL, Clish CB, Larson MG, Vasan RS, Lewis GD. Metabolic Architecture of Acute Exercise Response in Middle-Aged Adults in the Community. Circulation. 2020 11 17; 142(20):1905-1924. PMID: 32927962; PMCID: PMC8049528.
    Citations: 16     Fields:    Translation:Humans
  29. Aguilar-Pineda JA, Albaghdadi M, Jiang W, Lopez KJV, Del-Carpio GD, Valdez BG, Lindsay ME, Malhotra R, Lino Cardenas CL. Structural and functional analysis of female sex hormones against SARS-Cov2 cell entry. bioRxiv. 2020 Jul 29. PMID: 32766583.
    Citations:    
  30. Tian W, Jiang W, Yao J, Nicholson CJ, Li RH, Sigurslid HH, Wooster L, Rotter JI, Guo X, Malhotra R. Predictors of mortality in hospitalized COVID-19 patients: A systematic review and meta-analysis. J Med Virol. 2020 10; 92(10):1875-1883. PMID: 32441789; PMCID: PMC7280666.
    Citations: 193     Fields:    Translation:Humans
  31. Thayer TE, Lino Cardenas CL, Martyn T, Nicholson CJ, Traeger L, Wunderer F, Slocum C, Sigurslid H, Shakartzi HR, O'Rourke C, Shelton G, Buswell MD, Barnes H, Neitzel LR, Ledsky CD, Li JP, Burke MF, Farber-Eger E, Perrien DS, Kumar R, Corey KE, Wells QS, Bloch KD, Hong CC, Bloch DB, Malhotra R. The Role of Bone Morphogenetic Protein Signaling in Non-Alcoholic Fatty Liver Disease. Sci Rep. 2020 06 19; 10(1):9831. PMID: 32561790; PMCID: PMC7305229.
    Citations: 2     Fields:    Translation:AnimalsCells
  32. Nayor M, Houstis NE, Namasivayam M, Rouvina J, Hardin C, Shah RV, Ho JE, Malhotra R, Lewis GD. Impaired Exercise Tolerance in Heart Failure With Preserved Ejection Fraction: Quantification of Multiorgan System Reserve Capacity. JACC Heart Fail. 2020 08; 8(8):605-617. PMID: 32535122.
    Citations: 7     Fields:    Translation:Humans
  33. Puram RV, Erdil RM, Weber BN, Knelson EH, Van Beuningen AM, Wallwork R, Gilyard SN, Curtis BR, Ranganathan R, Leaf RK, Malhotra R. Thrombocytopenia and Thromboses in Myocardial Infarction Associated with Eptifibatide-Dependent Activating Antiplatelet Antibodies. Thromb Haemost. 2020 07; 120(7):1137-1141. PMID: 32483771.
    Citations:    Fields:    Translation:Humans
  34. Nayor M, Xanthakis V, Tanguay M, Blodgett JB, Shah RV, Schoenike M, Sbarbaro J, Farrell R, Malhotra R, Houstis NE, Velagaleti RS, Moore SA, Baggish AL, O'Connor GT, Ho JE, Larson MG, Vasan RS, Lewis GD. Clinical and Hemodynamic Associations and Prognostic Implications of Ventilatory Efficiency in Patients With Preserved Left Ventricular Systolic Function. Circ Heart Fail. 2020 05; 13(5):e006729. PMID: 32362167; PMCID: PMC7224335.
    Citations: 10     Fields:    Translation:Humans
  35. Wunderer F, Traeger L, Sigurslid HH, Meybohm P, Bloch DB, Malhotra R. The role of hepcidin and iron homeostasis in atherosclerosis. Pharmacol Res. 2020 03; 153:104664. PMID: 31991168.
    Citations: 15     Fields:    Translation:HumansAnimalsCells
  36. Kessler MD, Loesch DP, Perry JA, Heard-Costa NL, Taliun D, Cade BE, Wang H, Daya M, Ziniti J, Datta S, Celedón JC, Soto-Quiros ME, Avila L, Weiss ST, Barnes K, Redline SS, Vasan RS, Johnson AD, Mathias RA, Hernandez R, Wilson JG, Nickerson DA, Abecasis G, Browning SR, Zöllner S, O'Connell JR, Mitchell BD, O'Connor TD. De novo mutations across 1,465 diverse genomes reveal mutational insights and reductions in the Amish founder population. Proc Natl Acad Sci U S A. 2020 02 04; 117(5):2560-2569. PMID: 31964835; PMCID: PMC7007577.
    Citations: 20     Fields:    Translation:Humans
  37. Ho JE, Zern EK, Lau ES, Wooster L, Bailey CS, Cunningham T, Eisman AS, Hardin KM, Farrell R, Sbarbaro JA, Schoenike MW, Houstis NE, Baggish AL, Shah RV, Nayor M, Malhotra R, Lewis GD. Exercise Pulmonary Hypertension Predicts Clinical Outcomes in Patients With Dyspnea on Effort. J Am Coll Cardiol. 2020 01 07; 75(1):17-26. PMID: 31918830; PMCID: PMC7043927.
    Citations: 12     Fields:    Translation:Humans
  38. Lau ES, Cunningham T, Hardin KM, Liu E, Malhotra R, Nayor M, Lewis GD, Ho JE. Sex Differences in Cardiometabolic Traits and Determinants of Exercise Capacity in Heart Failure With Preserved Ejection Fraction. JAMA Cardiol. 2020 01 01; 5(1):30-37. PMID: 31664435.
    Citations: 8     Fields:    Translation:Humans
  39. Malhotra R, Mauer AC, Lino Cardenas CL, Guo X, Yao J, Zhang X, Wunderer F, Smith AV, Wong Q, Pechlivanis S, Hwang SJ, Wang J, Lu L, Nicholson CJ, Shelton G, Buswell MD, Barnes HJ, Sigurslid HH, Slocum C, Rourke CO, Rhee DK, Bagchi A, Nigwekar SU, Buys ES, Campbell CY, Harris T, Budoff M, Criqui MH, Rotter JI, Johnson AD, Song C, Franceschini N, Debette S, Hoffmann U, Kälsch H, Nöthen MM, Sigurdsson S, Freedman BI, Bowden DW, Jöckel KH, Moebus S, Erbel R, Feitosa MF, Gudnason V, Thanassoulis G, Zapol WM, Lindsay ME, Bloch DB, Post WS, O'Donnell CJ. HDAC9 is implicated in atherosclerotic aortic calcification and affects vascular smooth muscle cell phenotype. Nat Genet. 2019 11; 51(11):1580-1587. PMID: 31659325; PMCID: PMC6858575.
    Citations: 28     Fields:    Translation:HumansAnimals
  40. Hardin CC, Malhotra R, Petranovic M, Klassen S, Mihatov N, Oakley DH. Case 23-2019: A 52-Year-Old Man with Fever, Cough, and Hypoxemia. N Engl J Med. 2019 Jul 25; 381(4):359-369. PMID: 31340098.
    Citations:    Fields:    Translation:Humans
  41. Marrazzo F, Spina S, Zadek F, Lama T, Xu C, Larson G, Rezoagli E, Malhotra R, Zheng H, Bittner EA, Shelton K, Melnitchouk S, Roy N, Sundt TM, Riley WD, Williams P, Fisher D, Kacmarek RM, Thompson TB, Bonventre J, Zapol W, Ichinose F, Berra L. Protocol of a randomised controlled trial in cardiac surgical patients with endothelial dysfunction aimed to prevent postoperative acute kidney injury by administering nitric oxide gas. BMJ Open. 2019 07 04; 9(7):e026848. PMID: 31278097.
    Citations: 6     Fields:    Translation:Humans
  42. Ho JE, Zern EK, Wooster L, Bailey CS, Cunningham T, Eisman AS, Hardin KM, Zampierollo GA, Jarolim P, Pappagianopoulos PP, Malhotra R, Nayor M, Lewis GD. Differential Clinical Profiles, Exercise Responses, and Outcomes Associated With Existing HFpEF Definitions. Circulation. 2019 07 30; 140(5):353-365. PMID: 31132875; PMCID: PMC6684250.
    Citations: 21     Fields:    Translation:Humans
  43. Hayashida K, Miyazaki Y, Yu B, Silverman MG, Pinciroli R, Berra L, Malhotra R, Donnino MW, Ichinose F. Depletion of Vascular Nitric Oxide Contributes to Poor Outcomes after Cardiac Arrest. Am J Respir Crit Care Med. 2019 05 15; 199(10):1288-1290. PMID: 30785772; PMCID: PMC6519855.
    Citations: 2     Fields:    Translation:Humans
  44. Dewan P, Dixit A, Gomber S, Kotru M, Banerjee BD, Tyagi V, Malhotra RK. Serum and Urinary Hepcidin for Diagnosing Iron-deficiency Anemia in Under-5 Children. J Pediatr Hematol Oncol. 2019 May; 41(4):e216-e220. PMID: 30334902.
    Citations: 2     Fields:    Translation:Humans
  45. Ambrosy AP, Lewis GD, Malhotra R, Jones AD, Greene SJ, Fudim M, Coles A, Butler J, Sharma A, Hernandez AF, Mentz RJ. Identifying responders to oral iron supplementation in heart failure with a reduced ejection fraction: a post-hoc analysis of the IRONOUT-HF trial. J Cardiovasc Med (Hagerstown). 2019 Apr; 20(4):223-225. PMID: 30540649.
    Citations: 4     Fields:    Translation:Humans
  46. Nikolic I, Yung LM, Yang P, Malhotra R, Paskin-Flerlage SD, Dinter T, Bocobo GA, Tumelty KE, Faugno AJ, Troncone L, McNeil ME, Huang X, Coser KR, Lai CSC, Upton PD, Goumans MJ, Zamanian RT, Elliott CG, Lee A, Zheng W, Berasi SP, Huard C, Morrell NW, Chung RT, Channick RW, Roberts KE, Yu PB. Bone Morphogenetic Protein 9 Is a Mechanistic Biomarker of Portopulmonary Hypertension. Am J Respir Crit Care Med. 2019 04 01; 199(7):891-902. PMID: 30312106; PMCID: PMC6444661.
    Citations: 24     Fields:    Translation:Humans
  47. Hayashida K, Bagchi A, Miyazaki Y, Hirai S, Seth D, Silverman MG, Rezoagli E, Marutani E, Mori N, Magliocca A, Liu X, Berra L, Hindle AG, Donnino MW, Malhotra R, Bradley MO, Stamler JS, Ichinose F. Improvement in Outcomes After Cardiac Arrest and Resuscitation by Inhibition of S-Nitrosoglutathione Reductase. Circulation. 2019 02 05; 139(6):815-827. PMID: 30586713; PMCID: PMC6361681.
    Citations: 16     Fields:    Translation:HumansAnimalsCells
  48. Malhotra R, Wunderer F, Barnes HJ, Bagchi A, Buswell MD, O'Rourke CD, Slocum CL, Ledsky CD, Peneyra KM, Sigurslid H, Corman B, Johansson KB, Rhee DK, Bloch KD, Bloch DB. Hepcidin Deficiency Protects Against Atherosclerosis. Arterioscler Thromb Vasc Biol. 2019 02; 39(2):178-187. PMID: 30587002; PMCID: PMC6344241.
    Citations: 18     Fields:    Translation:AnimalsCells
  49. Lino Cardenas CL, Kessinger CW, Chou EL, Ghoshhajra B, Yeri AS, Das S, Weintraub NL, Malhotra R, Jaffer FA, Lindsay ME. HDAC9 complex inhibition improves smooth muscle-dependent stenotic vascular disease. JCI Insight. 2019 01 24; 4(2). PMID: 30674723.
    Citations: 10     Fields:    
  50. Hindle AG, Thoonen R, Jasien JV, Grange RMH, Amin K, Wise J, Ozaki M, Ritch R, Malhotra R, Buys ES. Identification of Candidate miRNA Biomarkers for Glaucoma. Invest Ophthalmol Vis Sci. 2019 01 02; 60(1):134-146. PMID: 30629727; PMCID: PMC6329203.
    Citations: 32     Fields:    Translation:Humans
  51. Portales-Castillo I, Kroshinsky D, Malhotra CK, Culber-Costley R, Cozzolino MG, Karparis S, Halasz CL, Goverman J, Manley HJ, Malhotra R, Nigwekar SU. Calciphylaxis-as a drug induced adverse event. Expert Opin Drug Saf. 2019 01; 18(1):29-35. PMID: 30574812.
    Citations: 3     Fields:    Translation:HumansAnimals
  52. Schleifer G, Marutani E, Ferrari M, Sharma R, Skinner O, Goldberger O, Grange RMH, Peneyra K, Malhotra R, Wepler M, Ichinose F, Bloch DB, Mootha VK, Zapol WM. Impaired hypoxic pulmonary vasoconstriction in a mouse model of Leigh syndrome. Am J Physiol Lung Cell Mol Physiol. 2019 02 01; 316(2):L391-L399. PMID: 30520688; PMCID: PMC6397345.
    Citations: 2     Fields:    Translation:AnimalsCells
  53. Fitzsimons MG, Baker K, Malhotra R, Gottlieb A, Lowenstein E, Zapol WM. Reducing the Incidence of Substance Use Disorders in Anesthesiology Residents: 13 Years of Comprehensive Urine Drug Screening. Anesthesiology. 2018 10; 129(4):821-828. PMID: 30020101.
    Citations: 2     Fields:    Translation:HumansPHPublic Health
  54. Nagasaka Y, Fernandez BO, Steinbicker AU, Spagnolli E, Malhotra R, Bloch DB, Bloch KD, Zapol WM, Feelisch M. Pharmacological preconditioning with inhaled nitric oxide (NO): Organ-specific differences in the lifetime of blood and tissue NO metabolites. Nitric Oxide. 2018 11 01; 80:52-60. PMID: 30114529.
    Citations: 9     Fields:    Translation:AnimalsCells
  55. Lin B, Srikanth P, Castle AC, Nigwekar S, Malhotra R, Galloway JL, Sykes DB, Rajagopal J. Modulating Cell Fate as a Therapeutic Strategy. Cell Stem Cell. 2018 09 06; 23(3):329-341. PMID: 29910150; PMCID: PMC6128730.
    Citations: 14     Fields:    Translation:HumansAnimals
  56. Eisman AS, Shah RV, Dhakal BP, Pappagianopoulos PP, Wooster L, Bailey C, Cunningham TF, Hardin KM, Baggish AL, Ho JE, Malhotra R, Lewis GD. Pulmonary Capillary Wedge Pressure Patterns During Exercise Predict Exercise Capacity and Incident Heart Failure. Circ Heart Fail. 2018 05; 11(5):e004750. PMID: 29695381.
    Citations: 39     Fields:    Translation:Humans
  57. Lino Cardenas CL, Kessinger CW, Cheng Y, MacDonald C, MacGillivray T, Ghoshhajra B, Huleihel L, Nuri S, Yeri AS, Jaffer FA, Kaminski N, Ellinor P, Weintraub NL, Malhotra R, Isselbacher EM, Lindsay ME. An HDAC9-MALAT1-BRG1 complex mediates smooth muscle dysfunction in thoracic aortic aneurysm. Nat Commun. 2018 03 08; 9(1):1009. PMID: 29520069.
    Citations: 49     Fields:    Translation:HumansAnimalsCells
  58. Bailey CS, Wooster LT, Buswell M, Patel S, Pappagianopoulos PP, Bakken K, White C, Tanguay M, Blodgett JB, Baggish AL, Malhotra R, Lewis GD. Post-Exercise Oxygen Uptake Recovery Delay: A Novel Index of Impaired Cardiac Reserve Capacity in Heart Failure. JACC Heart Fail. 2018 04; 6(4):329-339. PMID: 29525330.
    Citations: 8     Fields:    Translation:Humans
  59. Truong QA, Bhatia HS, Szymonifka J, Zhou Q, Lavender Z, Waxman AB, Semigran MJ, Malhotra R. A four-tier classification system of pulmonary artery metrics on computed tomography for the diagnosis and prognosis of pulmonary hypertension. J Cardiovasc Comput Tomogr. 2018 Jan - Feb; 12(1):60-66. PMID: 29254655; PMCID: PMC6934139.
    Citations: 4     Fields:    Translation:Humans
  60. Nigwekar SU, Jiramongkolchai P, Wunderer F, Bloch E, Ichinose R, Nazarian RM, Thadhani RI, Malhotra R, Bloch DB. Increased Bone Morphogenetic Protein Signaling in the Cutaneous Vasculature of Patients with Calciphylaxis. Am J Nephrol. 2017; 46(5):429-438. PMID: 29130990; PMCID: PMC5763243.
    Citations: 4     Fields:    Translation:HumansCells
  61. Muenster S, Lieb WS, Fabry G, Allen KN, Kamat SS, Guy AH, Dordea AC, Teixeira L, Tainsh RE, Yu B, Zhu W, Ashpole NE, Malhotra R, Brouckaert P, Bloch DB, Scherrer-Crosbie M, Stamer WD, Kuehn MH, Pasquale LR, Buys ES. The Ability of Nitric Oxide to Lower Intraocular Pressure Is Dependent on Guanylyl Cyclase. Invest Ophthalmol Vis Sci. 2017 09 01; 58(11):4826-4835. PMID: 28973329; PMCID: PMC5624778.
    Citations: 11     Fields:    Translation:Animals
  62. Hoeft K, Bloch DB, Graw JA, Malhotra R, Ichinose F, Bagchi A. Iron Loading Exaggerates the Inflammatory Response to the Toll-like Receptor 4 Ligand Lipopolysaccharide by Altering Mitochondrial Homeostasis. Anesthesiology. 2017 07; 127(1):121-135. PMID: 28430694; PMCID: PMC5478432.
    Citations: 12     Fields:    Translation:AnimalsCells
  63. Lewis GD, Malhotra R, Hernandez AF, McNulty SE, Smith A, Felker GM, Tang WHW, LaRue SJ, Redfield MM, Semigran MJ, Givertz MM, Van Buren P, Whellan D, Anstrom KJ, Shah MR, Desvigne-Nickens P, Butler J, Braunwald E. Effect of Oral Iron Repletion on Exercise Capacity in Patients With Heart Failure With Reduced Ejection Fraction and Iron Deficiency: The IRONOUT HF Randomized Clinical Trial. JAMA. 2017 May 16; 317(19):1958-1966. PMID: 28510680; PMCID: PMC5703044.
    Citations: 90     Fields:    Translation:HumansCTClinical Trials
  64. Nigwekar SU, Bloch DB, Nazarian RM, Vermeer C, Booth SL, Xu D, Thadhani RI, Malhotra R. Vitamin K-Dependent Carboxylation of Matrix Gla Protein Influences the Risk of Calciphylaxis. J Am Soc Nephrol. 2017 Jun; 28(6):1717-1722. PMID: 28049648; PMCID: PMC5461787.
    Citations: 43     Fields:    Translation:Humans
  65. Wepler M, Beloiartsev A, Buswell MD, Panigrahy D, Malhotra R, Buys ES, Radermacher P, Ichinose F, Bloch DB, Zapol WM. Soluble epoxide hydrolase deficiency or inhibition enhances murine hypoxic pulmonary vasoconstriction after lipopolysaccharide challenge. Am J Physiol Lung Cell Mol Physiol. 2016 Dec 01; 311(6):L1213-L1221. PMID: 27815261; PMCID: PMC5206400.
    Citations: 7     Fields:    Translation:Animals
  66. Muenster S, Beloiartsev A, Yu B, Du E, Abidi S, Dao M, Fabry G, Graw JA, Wepler M, Malhotra R, Fernandez BO, Feelisch M, Bloch KD, Bloch DB, Zapol WM. Exposure of Stored Packed Erythrocytes to Nitric Oxide Prevents Transfusion-associated Pulmonary Hypertension. Anesthesiology. 2016 11; 125(5):952-963. PMID: 27517645; PMCID: PMC5069190.
    Citations: 4     Fields:    Translation:AnimalsCells
  67. Yu B, Blaesi AH, Casey N, Raykhtsaum G, Zazzeron L, Jones R, Morrese A, Dobrynin D, Malhotra R, Bloch DB, Goldstein LE, Zapol WM. Detection and removal of impurities in nitric oxide generated from air by pulsed electrical discharge. Nitric Oxide. 2016 11 30; 60:16-23. PMID: 27592386.
    Citations: 5     Fields:    Translation:AnimalsCellsPHPublic Health
  68. Graw JA, Mayeur C, Rosales I, Liu Y, Sabbisetti VS, Riley FE, Rechester O, Malhotra R, Warren HS, Colvin RB, Bonventre JV, Bloch DB, Zapol WM. Haptoglobin or Hemopexin Therapy Prevents Acute Adverse Effects of Resuscitation After Prolonged Storage of Red Cells. Circulation. 2016 09 27; 134(13):945-60. PMID: 27515135; PMCID: PMC5039096.
    Citations: 30     Fields:    Translation:HumansAnimalsCells
  69. Malhotra R, Bakken K, D'Elia E, Lewis GD. Cardiopulmonary Exercise Testing in Heart Failure. JACC Heart Fail. 2016 08; 4(8):607-16. PMID: 27289406.
    Citations: 78     Fields:    Translation:Humans
  70. Malhotra R, Dhakal BP, Eisman AS, Pappagianopoulos PP, Dress A, Weiner RB, Baggish AL, Semigran MJ, Lewis GD. Pulmonary Vascular Distensibility Predicts Pulmonary Hypertension Severity, Exercise Capacity, and Survival in Heart Failure. Circ Heart Fail. 2016 06; 9(6). PMID: 27301469.
    Citations: 26     Fields:    Translation:Humans
  71. O'Rourke C, Shelton G, Hutcheson JD, Burke MF, Martyn T, Thayer TE, Shakartzi HR, Buswell MD, Tainsh RE, Yu B, Bagchi A, Rhee DK, Wu C, Derwall M, Buys ES, Yu PB, Bloch KD, Aikawa E, Bloch DB, Malhotra R. Calcification of Vascular Smooth Muscle Cells and Imaging of Aortic Calcification and Inflammation. J Vis Exp. 2016 05 31; (111). PMID: 27284788.
    Citations: 8     Fields:    Translation:HumansAnimals
  72. Dordea AC, Vandenwijngaert S, Garcia V, Tainsh RE, Nathan DI, Allen K, Raher MJ, Tainsh LT, Zhang F, Lieb WS, Mikelman S, Kirby A, Stevens C, Thoonen R, Hindle AG, Sips PY, Falck JR, Daly MJ, Brouckaert P, Bloch KD, Bloch DB, Malhotra R, Schwartzman ML, Buys ES. Androgen-sensitive hypertension associated with soluble guanylate cyclase-a1 deficiency is mediated by 20-HETE. Am J Physiol Heart Circ Physiol. 2016 06 01; 310(11):H1790-800. PMID: 27199131; PMCID: PMC4935526.
    Citations: 4     Fields:    Translation:Animals
  73. Lewis GD, Semigran MJ, Givertz MM, Malhotra R, Anstrom KJ, Hernandez AF, Shah MR, Braunwald E. Oral Iron Therapy for Heart Failure With Reduced Ejection Fraction: Design and Rationale for Oral Iron Repletion Effects on Oxygen Uptake in Heart Failure. Circ Heart Fail. 2016 05; 9(5). PMID: 27140203.
    Citations: 16     Fields:    Translation:Humans
  74. Dordea AC, Bray MA, Allen K, Logan DJ, Fei F, Malhotra R, Gregory MS, Carpenter AE, Buys ES. An open-source computational tool to automatically quantify immunolabeled retinal ganglion cells. Exp Eye Res. 2016 06; 147:50-56. PMID: 27119563; PMCID: PMC4903927.
    Citations: 11     Fields:    Translation:AnimalsCells
  75. Li X, Rhee DK, Malhotra R, Mayeur C, Hurst LA, Ager E, Shelton G, Kramer Y, McCulloh D, Keefe D, Bloch KD, Bloch DB, Peterson RT. Progesterone receptor membrane component-1 regulates hepcidin biosynthesis. J Clin Invest. 2016 Jan; 126(1):389-401. PMID: 26657863; PMCID: PMC4701562.
    Citations: 35     Fields:    Translation:HumansAnimalsCells
  76. Niehaus ED, Malhotra R, Cocca-Spofford D, Semigran M, Lewis GD. Repletion of Iron Stores With the Use of Oral Iron Supplementation in Patients With Systolic Heart Failure. J Card Fail. 2015 Aug; 21(8):694-7. PMID: 26028263.
    Citations: 10     Fields:    Translation:Humans
  77. Nigwekar SU, Kroshinsky D, Nazarian RM, Goverman J, Malhotra R, Jackson VA, Kamdar MM, Steele DJ, Thadhani RI. Calciphylaxis: risk factors, diagnosis, and treatment. Am J Kidney Dis. 2015 Jul; 66(1):133-46. PMID: 25960299; PMCID: PMC4696752.
    Citations: 93     Fields:    Translation:HumansAnimals
  78. Malhotra R, Burke MF, Martyn T, Shakartzi HR, Thayer TE, O'Rourke C, Li P, Derwall M, Spagnolli E, Kolodziej SA, Hoeft K, Mayeur C, Jiramongkolchai P, Kumar R, Buys ES, Yu PB, Bloch KD, Bloch DB. Inhibition of bone morphogenetic protein signal transduction prevents the medial vascular calcification associated with matrix Gla protein deficiency. PLoS One. 2015; 10(1):e0117098. PMID: 25603410.
    Citations: 38     Fields:    Translation:AnimalsCells
  79. Dhakal BP, Malhotra R, Murphy RM, Pappagianopoulos PP, Baggish AL, Weiner RB, Houstis NE, Eisman AS, Hough SS, Lewis GD. Mechanisms of exercise intolerance in heart failure with preserved ejection fraction: the role of abnormal peripheral oxygen extraction. Circ Heart Fail. 2015 Mar; 8(2):286-94. PMID: 25344549.
    Citations: 123     Fields:    Translation:Humans
  80. Bhatia RS, Dudzinski DM, Malhotra R, Milford CE, Yoerger Sanborn DM, Picard MH, Weiner RB. Educational intervention to reduce outpatient inappropriate echocardiograms: a randomized control trial. JACC Cardiovasc Imaging. 2014 Sep; 7(9):857-66. PMID: 25129520.
    Citations: 13     Fields:    Translation:Humans
  81. Nigwekar SU, Solid CA, Ankers E, Malhotra R, Eggert W, Turchin A, Thadhani RI, Herzog CA. Quantifying a rare disease in administrative data: the example of calciphylaxis. J Gen Intern Med. 2014 Aug; 29 Suppl 3:S724-31. PMID: 25029979.
    Citations: 26     Fields:    Translation:Humans
  82. Bloch DB, Li P, Bloch EG, Berenson DF, Galdos RL, Arora P, Malhotra R, Wu C, Yang W. LMKB/MARF1 localizes to mRNA processing bodies, interacts with Ge-1, and regulates IFI44L gene expression. PLoS One. 2014; 9(4):e94784. PMID: 24755989.
    Citations: 11     Fields:    Translation:HumansAnimalsCells
  83. Gray Gilstrap L, Niehaus E, Malhotra R, Ton VK, Watts J, Seldin DC, Madsen JC, Semigran MJ. Predictors of survival to orthotopic heart transplant in patients with light chain amyloidosis. J Heart Lung Transplant. 2014 Feb; 33(2):149-56. PMID: 24200511.
    Citations: 18     Fields:    Translation:Humans
  84. Baron DM, Beloiartsev A, Nakagawa A, Martyn T, Stowell CP, Malhotra R, Mayeur C, Bloch KD, Zapol WM. Adverse effects of hemorrhagic shock resuscitation with stored blood are ameliorated by inhaled nitric oxide in lambs*. Crit Care Med. 2013 Nov; 41(11):2492-501. PMID: 23887236; PMCID: PMC3812272.
    Citations: 17     Fields:    Translation:AnimalsCells
  85. Weiner RB, Wang F, Isaacs SK, Malhotra R, Berkstresser B, Kim JH, Hutter AM, Picard MH, Wang TJ, Baggish AL. Blood pressure and left ventricular hypertrophy during American-style football participation. Circulation. 2013 Jul 30; 128(5):524-31. PMID: 23897848.
    Citations: 25     Fields:    Translation:Humans
  86. Chatterjee NA, Murphy RM, Malhotra R, Dhakal BP, Baggish AL, Pappagianopoulos PP, Hough SS, Semigran MJ, Lewis GD. Prolonged mean VO2 response time in systolic heart failure: an indicator of impaired right ventricular-pulmonary vascular function. Circ Heart Fail. 2013 May; 6(3):499-507. PMID: 23572493.
    Citations: 8     Fields:    Translation:Humans
  87. Buys ES, Ko YC, Alt C, Hayton SR, Jones A, Tainsh LT, Ren R, Giani A, Clerte' M, Abernathy E, Tainsh RE, Oh DJ, Malhotra R, Arora P, de Waard N, Yu B, Turcotte R, Nathan D, Scherrer-Crosbie M, Loomis SJ, Kang JH, Lin CP, Gong H, Rhee DJ, Brouckaert P, Wiggs JL, Gregory MS, Pasquale LR, Bloch KD, Ksander BR. Soluble Guanylate Cyclase a1-Deficient Mice: a novel murine model for Primary Open Angle Glaucoma. Ann Neurosci. 2013 Apr; 20(2):65-6. PMID: 25206015.
    Citations: 1     
  88. Malhotra R, Paskin-Flerlage S, Zamanian RT, Zimmerman P, Schmidt JW, Deng DY, Southwood M, Spencer R, Lai CS, Parker W, Channick RN, Morrell NW, Elliott CG, Yu PB. Circulating angiogenic modulatory factors predict survival and functional class in pulmonary arterial hypertension. Pulm Circ. 2013 Apr; 3(2):369-80. PMID: 24015338; PMCID: PMC3757832.
    Citations: 21     
  89. Gilstrap LG, Malhotra R, Peltier-Saxe D, Slicas D, Pineda E, Culhane-Hermann C, Cook N, Fernandez-Golarz C, Wood M. Community-based primary prevention programs decrease the rate of metabolic syndrome among socioeconomically disadvantaged women. J Womens Health (Larchmt). 2013 Apr; 22(4):322-9. PMID: 23540328.
    Citations: 8     Fields:    Translation:HumansPHPublic Health
  90. Buys ES, Ko YC, Alt C, Hayton SR, Jones A, Tainsh LT, Ren R, Giani A, Clerté M, Abernathy E, Tainsh RE, Oh DJ, Malhotra R, Arora P, de Waard N, Yu B, Turcotte R, Nathan D, Scherrer-Crosbie M, Loomis SJ, Kang JH, Lin CP, Gong H, Rhee DJ, Brouckaert P, Wiggs JL, Gregory MS, Pasquale LR, Bloch KD, Ksander BR. Soluble guanylate cyclase a1-deficient mice: a novel murine model for primary open angle glaucoma. PLoS One. 2013; 8(3):e60156. PMID: 23527308.
    Citations: 31     Fields:    Translation:AnimalsCells
  91. Thanassoulis G, Campbell CY, Owens DS, Smith JG, Smith AV, Peloso GM, Kerr KF, Pechlivanis S, Budoff MJ, Harris TB, Malhotra R, O'Brien KD, Kamstrup PR, Nordestgaard BG, Tybjaerg-Hansen A, Allison MA, Aspelund T, Criqui MH, Heckbert SR, Hwang SJ, Liu Y, Sjogren M, van der Pals J, Kälsch H, Mühleisen TW, Nöthen MM, Cupples LA, Caslake M, Di Angelantonio E, Danesh J, Rotter JI, Sigurdsson S, Wong Q, Erbel R, Kathiresan S, Melander O, Gudnason V, O'Donnell CJ, Post WS. Genetic associations with valvular calcification and aortic stenosis. N Engl J Med. 2013 Feb 07; 368(6):503-12. PMID: 23388002; PMCID: PMC3766627.
    Citations: 252     Fields:    Translation:Humans
  92. Buys ES, Raher MJ, Kirby A, Shahid M, Mohd S, Baron DM, Hayton SR, Tainsh LT, Sips PY, Rauwerdink KM, Yan Q, Tainsh RE, Shakartzi HR, Stevens C, Decaluwé K, Rodrigues-Machado Mda G, Malhotra R, Van de Voorde J, Wang T, Brouckaert P, Daly MJ, Bloch KD. Genetic modifiers of hypertension in soluble guanylate cyclase a1-deficient mice. J Clin Invest. 2012 Jun; 122(6):2316-25. PMID: 22565307; PMCID: PMC3366402.
    Citations: 18     Fields:    Translation:HumansAnimalsCells
  93. Hawthorne KM, Johri AM, Malhotra R, Hung J, Baggish A, Picard MH. Quality Assessment in Dobutamine Stress Echocardiography: What are the Clinical Predictors Associated With a Non-Diagnostic Test? Cardiol Res. 2012 Apr; 3(2):73-79. PMID: 28348675; PMCID: PMC5358144.
    Citations: 1     
  94. Baron DM, Yu B, Lei C, Bagchi A, Beloiartsev A, Stowell CP, Steinbicker AU, Malhotra R, Bloch KD, Zapol WM. Pulmonary hypertension in lambs transfused with stored blood is prevented by breathing nitric oxide. Anesthesiology. 2012 Mar; 116(3):637-47. PMID: 22293717; PMCID: PMC3293704.
    Citations: 32     Fields:    Translation:Animals
  95. Kim JH, Malhotra R, Chiampas G, d'Hemecourt P, Troyanos C, Cianca J, Smith RN, Wang TJ, Roberts WO, Thompson PD, Baggish AL. Cardiac arrest during long-distance running races. N Engl J Med. 2012 Jan 12; 366(2):130-40. PMID: 22236223.
    Citations: 136     Fields:    Translation:Humans
  96. Derwall M, Malhotra R, Lai CS, Beppu Y, Aikawa E, Seehra JS, Zapol WM, Bloch KD, Yu PB. Inhibition of bone morphogenetic protein signaling reduces vascular calcification and atherosclerosis. Arterioscler Thromb Vasc Biol. 2012 Mar; 32(3):613-22. PMID: 22223731.
    Citations: 109     Fields:    Translation:HumansAnimalsCells
  97. Murphy RM, Shah RV, Malhotra R, Pappagianopoulos PP, Hough SS, Systrom DM, Semigran MJ, Lewis GD. Exercise oscillatory ventilation in systolic heart failure: an indicator of impaired hemodynamic response to exercise. Circulation. 2011 Sep 27; 124(13):1442-51. PMID: 21875912; PMCID: PMC3415253.
    Citations: 25     Fields:    Translation:Humans
  98. Steinbicker AU, Liu H, Jiramongkolchai K, Malhotra R, Choe EY, Busch CJ, Graveline AR, Kao SM, Nagasaka Y, Ichinose F, Buys ES, Brouckaert P, Zapol WM, Bloch KD. Nitric oxide regulates pulmonary vascular smooth muscle cell expression of the inducible cAMP early repressor gene. Nitric Oxide. 2011 Oct 30; 25(3):294-302. PMID: 21642009.
    Citations: 6     Fields:    Translation:AnimalsCells
  99. Malhotra R, Hess D, Lewis GD, Bloch KD, Waxman AB, Semigran MJ. Vasoreactivity to inhaled nitric oxide with oxygen predicts long-term survival in pulmonary arterial hypertension. Pulm Circ. 2011 Apr; 1(2):250-258. PMID: 22020367.
    Citations: 18     
  100. Hartzell M, Malhotra R, Yared K, Rosenfield HR, Walker JD, Wood MJ. Effect of gender on treatment and outcomes in severe aortic stenosis. Am J Cardiol. 2011 Jun 01; 107(11):1681-6. PMID: 21440885; PMCID: PMC5758865.
    Citations: 7     Fields:    Translation:Humans
  101. Lewis GD, Murphy RM, Shah RV, Pappagianopoulos PP, Malhotra R, Bloch KD, Systrom DM, Semigran MJ. Pulmonary vascular response patterns during exercise in left ventricular systolic dysfunction predict exercise capacity and outcomes. Circ Heart Fail. 2011 May; 4(3):276-85. PMID: 21292991.
    Citations: 36     Fields:    Translation:Humans
  102. Atochin DN, Yuzawa I, Li Q, Rauwerdink KM, Malhotra R, Chang J, Brouckaert P, Ayata C, Moskowitz MA, Bloch KD, Huang PL, Buys ES. Soluble guanylate cyclase alpha1beta1 limits stroke size and attenuates neurological injury. Stroke. 2010 Aug; 41(8):1815-9. PMID: 20595671.
    Citations: 15     Fields:    Translation:Animals
  103. Beppu H, Malhotra R, Beppu Y, Lepore JJ, Parmacek MS, Bloch KD. BMP type II receptor regulates positioning of outflow tract and remodeling of atrioventricular cushion during cardiogenesis. Dev Biol. 2009 Jul 15; 331(2):167-75. PMID: 19409885.
    Citations: 35     Fields:    Translation:Animals
  104. Refaat M, Hyle E, Malhotra R, Seidman D, Dey B. Linezolid-induced lingua villosa nigra. Am J Med. 2008 Jun; 121(6):e1. PMID: 18501207.
    Citations: 5     Fields:    Translation:Humans
  105. Pocket Medicine 3rd edition (edited by Marc Sabatine). Cardiology. 2007.
  106. Malhotra R, Zhai GG, Delaney M, Latham D, Nestler U, Zhang M, Mukherjee N, Song Q, Robe P, Chakravarti A. J Neurooncol. Radiation enhances the invasive potential of primary glioblastoma cells via activation of the Rho signaling pathway. 2006; 76(3):227-37.
  107. Zhong X, Malhotra R, Guidotti G. A eukaryotic carboxyl-terminal signal sequence translocating large hydrophilic domains across membranes. FEBS Lett. 2005 Oct 24; 579(25):5643-50. PMID: 16214140.
    Citations: 1     Fields:    Translation:AnimalsCells
  108. Chakravarti A, Zhai GG, Zhang M, Malhotra R, Latham DE, Delaney MA, Robe P, Nestler U, Song Q, Loeffler J. Survivin enhances radiation resistance in primary human glioblastoma cells via caspase-independent mechanisms. Oncogene. 2004 Sep 30; 23(45):7494-506. PMID: 15326475.
    Citations: 83     Fields:    Translation:HumansCells
  109. Malhotra R. and Sabatine M.S. Heart and Metabolism. Risk Stratification and Outcome in Non-ST Segment Elevation Acute Coronary Syndromes. 2004; (23):13-18.
  110. Zhong X, Malhotra R, Guidotti G. ATP uptake in the Golgi and extracellular release require Mcd4 protein and the vacuolar H+-ATPase. J Biol Chem. 2003 Aug 29; 278(35):33436-44. PMID: 12807869.
    Citations: 15     Fields:    Translation:AnimalsCells
  111. Zhong X, Malhotra R, Woodruff R, Guidotti G. Mammalian plasma membrane ecto-nucleoside triphosphate diphosphohydrolase 1, CD39, is not active intracellularly. The N-glycosylation state of CD39 correlates with surface activity and localization. J Biol Chem. 2001 Nov 02; 276(44):41518-25. PMID: 11546800.
    Citations: 18     Fields:    Translation:AnimalsCells
  112. Zhong X, Malhotra R, Guidotti G. Regulation of yeast ectoapyrase ynd1p activity by activator subunit Vma13p of vacuolar H+-ATPase. J Biol Chem. 2000 Nov 10; 275(45):35592-9. PMID: 10954728.
    Citations: 9     Fields:    Translation:AnimalsCells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.