Harvard Catalyst Profiles

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Kristine N. Brazin, Ph.D.

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Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Mallis RJ, Brazin KN, Duke-Cohan JS, Hwang W, Wang JH, Wagner G, Arthanari H, Lang MJ, Reinherz EL. NMR: an essential structural tool for integrative studies of T cell development, pMHC ligand recognition and TCR mechanobiology. J Biomol NMR. 2019 Jul; 73(6-7):319-332. PMID: 30815789.
    Citations:    
  2. Brazin KN, Mallis RJ, Boeszoermenyi A, Feng Y, Yoshizawa A, Reche PA, Kaur P, Bi K, Hussey RE, Duke-Cohan JS, Song L, Wagner G, Arthanari H, Lang MJ, Reinherz EL. The T Cell Antigen Receptor a Transmembrane Domain Coordinates Triggering through Regulation of Bilayer Immersion and CD3 Subunit Associations. Immunity. 2018 11 20; 49(5):829-841.e6. PMID: 30389415.
    Citations:    Fields:    
  3. Feng Y, Brazin KN, Kobayashi E, Mallis RJ, Reinherz EL, Lang MJ. Mechanosensing drives acuity of aß T-cell recognition. Proc Natl Acad Sci U S A. 2017 09 26; 114(39):E8204-E8213. PMID: 28811364.
    Citations: 8     Fields:    Translation:AnimalsCells
  4. Brazin KN, Mallis RJ, Das DK, Feng Y, Hwang W, Wang JH, Wagner G, Lang MJ, Reinherz EL. Structural Features of the aßTCR Mechanotransduction Apparatus That Promote pMHC Discrimination. Front Immunol. 2015; 6:441. PMID: 26388869.
    Citations: 9     
  5. Brazin KN, Mallis RJ, Li C, Keskin DB, Arthanari H, Gao Y, Wu SL, Karger BL, Wagner G, Reinherz EL. Constitutively oxidized CXXC motifs within the CD3 heterodimeric ectodomains of the T cell receptor complex enforce the conformation of juxtaposed segments. J Biol Chem. 2015 Jan 2; 290(1):239. PMID: 25556239.
    Citations:    
  6. Brazin KN, Mallis RJ, Li C, Keskin DB, Arthanari H, Gao Y, Wu SL, Karger BL, Wagner G, Reinherz EL. Constitutively oxidized CXXC motifs within the CD3 heterodimeric ectodomains of the T cell receptor complex enforce the conformation of juxtaposed segments. J Biol Chem. 2014 Jul 04; 289(27):18880-92. PMID: 24849600.
    Citations: 8     Fields:    Translation:HumansAnimalsCells
  7. Kim ST, Shin Y, Brazin K, Mallis RJ, Sun ZY, Wagner G, Lang MJ, Reinherz EL. TCR Mechanobiology: Torques and Tunable Structures Linked to Early T Cell Signaling. Front Immunol. 2012; 3:76. PMID: 22566957.
    Citations: 26     
  8. Mallis RJ, Brazin KN, Fulton DB, Andreotti AH. Structural characterization of a proline-driven conformational switch within the Itk SH2 domain. Nat Struct Biol. 2002 Dec; 9(12):900-5. PMID: 12402030.
    Citations: 37     Fields:    Translation:AnimalsCells
  9. Brazin KN, Mallis RJ, Fulton DB, Andreotti AH. Regulation of the tyrosine kinase Itk by the peptidyl-prolyl isomerase cyclophilin A. Proc Natl Acad Sci U S A. 2002 Feb 19; 99(4):1899-904. PMID: 11830645.
    Citations: 76     Fields:    Translation:HumansCells
  10. Laederach A, Cradic KW, Brazin KN, Zamoon J, Fulton DB, Huang XY, Andreotti AH. Competing modes of self-association in the regulatory domains of Bruton's tyrosine kinase: intramolecular contact versus asymmetric homodimerization. Protein Sci. 2002 Jan; 11(1):36-45. PMID: 11742120.
    Citations: 13     Fields:    Translation:HumansCells
  11. Mallis RJ, Brazin K, Jez JM, Wilson EK, Dieckmann GR, Robic S, Harrahy J. Proteins: the complete works. Trends Biochem Sci. 2001 Nov; 26(11):642-3. PMID: 11701309.
    Citations:    Fields:    Translation:HumansAnimalsCells
  12. Brazin KN, Fulton DB, Andreotti AH. A specific intermolecular association between the regulatory domains of a Tec family kinase. J Mol Biol. 2000 Sep 22; 302(3):607-23. PMID: 10986122.
    Citations: 26     Fields:    Translation:Cells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.