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Peter Howard Stone, M.D.

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Mentoring
Vascular Basis for the Treatmnet of Myocardial Ischemia
Part Time/Continuation, 09/01/99 - 05/30/00
Vascular Basis for the Treatmnet of Myocardial Ischemia
Summer/Continuation, 06/01/99 - 08/31/99
Vascular Basis for the Treatmnet of Myocardial Ischemia
Part Time, 09/07/98 - 06/30/99

Research
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. R01HL140498 (TEARNEY, GUILLERMO J) Jan 1, 2018 - Dec 31, 2022
    NIH/NHLBI
    Unique value of real-time shear stress to enhance coronary disease management
    Role: Co-Principal Investigator
  2. P41RR013622 (GOLDBERGER, ARY LOUIS) Jul 1, 2000 - Jun 30, 2004
    NIH/NCRR
    Research Resource for Complex Physiologic Signals
    Role: Co-Principal Investigator
  3. P01ES009825 (GOLD, DIANE R) Sep 27, 1999 - Jul 31, 2012
    NIH/NIEHS
    AMBIENT PARTICLES AND CARDIAC VULNERABILITY IN HUMANS
    Role: Co-Principal Investigator
  4. R01HL038780 (STONE, PETER HOWARD) Aug 1, 1989 - Jul 31, 2001
    NIH/NHLBI
    VASCULAR BASIS FOR THE TREATMENT OF ISCHEMIA
    Role: Principal Investigator
  5. R01HL042419 (BRAUNWALD, EUGENE) Apr 1, 1989 - May 31, 1992
    NIH/NHLBI
    THROMBOLYSIS IN MYOCARDIAL ISCHEMIA-CORE APPLICATION
    Role: Co-Principal Investigator

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Ferraro RA, van Rosendael AR, Lu Y, Andreini D, Al-Mallah MH, Cademartiri F, Chinnaiyan K, Chow BJW, Conte E, Cury RC, Feuchtner G, de Araújo Gonçalves P, Hadamitzky M, Kim YJ, Leipsic J, Maffei E, Marques H, Plank F, Pontone G, Raff GL, Villines TC, Lee SE, Al'Aref SJ, Baskaran L, Cho I, Danad I, Gransar H, Budoff MJ, Samady H, Stone PH, Virmani R, Narula J, Berman DS, Chang HJ, Bax JJ, Min JK, Shaw LJ, Lin FY. Non-obstructive high-risk plaques increase the risk of future culprit lesions comparable to obstructive plaques without high-risk features: the ICONIC study. Eur Heart J Cardiovasc Imaging. 2020 Jun 13. PMID: 32535636.
    Citations:    
  2. Tomaniak M, Katagiri Y, Modolo R, Silva R, Khamis RY, Bourantas CV, Torii R, Wentzel JJ, Gijsen FJH, van Soest G, Stone PH, West NEJ, Maehara A, Lerman A, van der Steen AFW, Lüscher TF, Virmani R, Koenig W, Stone GW, Muller JE, Wijns W, Serruys PW, Onuma Y. Vulnerable plaques and patients: state-of-the-art. Eur Heart J. 2020 May 13. PMID: 32402086.
    Citations:    
  3. Bourantas CV, Zanchin T, Torii R, Serruys PW, Karagiannis A, Ramasamy A, Safi H, Coskun AU, Koning G, Onuma Y, Zanchin C, Krams R, Mathur A, Baumbach A, Mintz G, Windecker S, Lansky A, Maehara A, Stone PH, Raber L, Stone GW. Shear Stress Estimated by Quantitative Coronary Angiography Predicts Plaques Prone to Progress and Cause Events. JACC Cardiovasc Imaging. 2020 May 08. PMID: 32417338.
    Citations:    
  4. Baskaran L, Al'Aref SJ, Maliakal G, Lee BC, Xu Z, Choi JW, Lee SE, Sung JM, Lin FY, Dunham S, Mosadegh B, Kim YJ, Gottlieb I, Lee BK, Chun EJ, Cademartiri F, Maffei E, Marques H, Shin S, Choi JH, Chinnaiyan K, Hadamitzky M, Conte E, Andreini D, Pontone G, Budoff MJ, Leipsic JA, Raff GL, Virmani R, Samady H, Stone PH, Berman DS, Narula J, Bax JJ, Chang HJ, Min JK, Shaw LJ. Automatic segmentation of multiple cardiovascular structures from cardiac computed tomography angiography images using deep learning. PLoS One. 2020; 15(5):e0232573. PMID: 32374784.
    Citations:    
  5. Haemmig S, Yang D, Sun X, Das D, Ghaffari S, Molinaro R, Chen L, Deng Y, Freeman D, Moullan N, Tesmenitsky Y, Wara AKMK, Simion V, Shvartz E, Lee JF, Yang T, Sukova G, Marto JA, Stone PH, Lee WL, Auwerx J, Libby P, Feinberg MW. Long noncoding RNA SNHG12 integrates a DNA-PK-mediated DNA damage response and vascular senescence. Sci Transl Med. 2020 Feb 19; 12(531). PMID: 32075942.
    Citations:    
  6. van Rosendael AR, Lin FY, Ma X, van den Hoogen IJ, Gianni U, Al Hussein O, Al'Aref SJ, Peña JM, Andreini D, Al-Mallah MH, Budoff MJ, Cademartiri F, Chinnaiyan K, Choi JH, Conte E, Marques H, de Araújo Gonçalves P, Gottlieb I, Hadamitzky M, Leipsic JA, Maffei E, Pontone G, Raff GL, Shin S, Kim YJ, Lee BK, Chun EJ, Sung JM, Lee SE, Berman DS, Virmani R, Samady H, Stone PH, Narula J, Bax JJ, Shaw LJ, Min JK, Chang HJ. Percent atheroma volume: Optimal variable to report whole-heart atherosclerotic plaque burden with coronary CTA, the PARADIGM study. J Cardiovasc Comput Tomogr. 2020 Jan 30. PMID: 32063545.
    Citations:    
  7. van Rosendael AR, Narula J, Lin FY, van den Hoogen IJ, Gianni U, Al Hussein Alawamlh O, Dunham PC, Peña JM, Lee SE, Andreini D, Cademartiri F, Chinnaiyan K, Chow BJW, Conte E, Cury RC, Feuchtner G, Hadamitzky M, Kim YJ, Leipsic J, Maffei E, Marques H, de Araújo Gonçalves P, Plank F, Pontone G, Raff GL, Villines TC, Weirich HG, Al'Aref SJ, Baskaran L, Cho I, Danad I, Han D, Heo R, Lee JH, Rivzi A, Stuijfzand WJ, Gransar H, Lu Y, Sung JM, Park HB, Samady H, Stone PH, Virmani R, Budoff MJ, Berman DS, Chang HJ, Bax JJ, Min JK, Shaw LJ. Association of High-Density Calcified 1K Plaque With Risk of Acute Coronary Syndrome. JAMA Cardiol. 2020 Jan 22. PMID: 31968065.
    Citations:    
  8. Samady H, Molony DS, Coskun AU, Varshney AS, De Bruyne B, Stone PH. Risk stratification of coronary plaques using physiologic characteristics by CCTA: Focus on shear stress. J Cardiovasc Comput Tomogr. 2019 Dec 04. PMID: 31870744.
    Citations:    
  9. Newman JD, Alexander KP, Gu X, O'Brien SM, Boden WE, Govindan SC, Senior R, Moorthy N, Rezende PC, Demkow M, Lopez-Sendon JL, Bockeria O, Pandit N, Gosselin G, Stone PH, Spertus JA, Stone GW, Fleg JL, Hochman JS, Maron DJ. Baseline Predictors of Low-Density Lipoprotein Cholesterol and Systolic Blood Pressure Goal Attainment After 1 Year in the ISCHEMIA Trial. Circ Cardiovasc Qual Outcomes. 2019 11; 12(11):e006002. PMID: 31718297.
    Citations:    
  10. Lee SE, Sung JM, Andreini D, Al-Mallah MH, Budoff MJ, Cademartiri F, Chinnaiyan K, Choi JH, Chun EJ, Conte E, Gottlieb I, Hadamitzky M, Kim YJ, Lee BK, Leipsic JA, Maffei E, Marques H, de Araújo Gonçalves P, Pontone G, Raff GL, Shin S, Stone PH, Samady H, Virmani R, Narula J, Berman DS, Shaw LJ, Bax JJ, Lin FY, Min JK, Chang HJ. Differences in Progression to Obstructive Lesions per High-Risk Plaque Features and Plaque Volumes With CCTA. JACC Cardiovasc Imaging. 2020 Jun; 13(6):1409-1417. PMID: 31734214.
    Citations:    
  11. Lee SE, Sung JM, Andreini D, Budoff MJ, Cademartiri F, Chinnaiyan K, Choi JH, Chun EJ, Conte E, Gottlieb I, Hadamitzky M, Kim YJ, Kumar A, Lee BK, Leipsic JA, Maffei E, Marques H, Pontone G, Raff G, Shin S, Stone PH, Samady H, Virmani R, Narula J, Berman DS, Shaw LJ, Bax JJ, Lin FY, Min JK, Chang HJ. Differential association between the progression of coronary artery calcium score and coronary plaque volume progression according to statins: the Progression of AtheRosclerotic PlAque DetermIned by Computed TomoGraphic Angiography Imaging (PARADIGM) study. Eur Heart J Cardiovasc Imaging. 2019 Nov 01; 20(11):1307-1314. PMID: 30789215.
    Citations:    
  12. Stone PH, Coskun AU. The effect of multidirectional wall shear stress on plaque characteristics: delving deeper into local shear stress metrics. EuroIntervention. 2019 Oct 20; 15(8):656-658. PMID: 31625914.
    Citations:    
  13. Stone PH. The Hazardous Longitudinal Heterogeneity of Plaques: A Complex Mountain Range, Not a Single Volcano. JACC Cardiovasc Imaging. 2020 May; 13(5):1219-1220. PMID: 31326495.
    Citations:    
  14. Stone PH. Evaluation of individual plaque risk based on plaque anatomic and biomechanical characteristics: methodologies and clinical applications are approaching an inflection point. Eur Heart J. 2019 05 07; 40(18):1423-1425. PMID: 31005992.
    Citations:    
  15. Won KB, Lee SE, Lee BK, Park HB, Heo R, Rizvi A, Hadamitzky M, Kim YJ, Sung JM, Conte E, Andreini D, Pontone G, Budoff MJ, Gottlieb I, Chun EJ, Cademartiri F, Maffei E, Marques H, Leipsic JA, Shin S, Choi JH, Virmani R, Samady H, Stone PH, Berman DS, Narula J, Shaw LJ, Bax JJ, Min JK, Chang HJ. Longitudinal quantitative assessment of coronary plaque progression related to body mass index using serial coronary computed tomography angiography. Eur Heart J Cardiovasc Imaging. 2019 May 01; 20(5):591-599. PMID: 30657884.
    Citations:    Fields:    
  16. Andreou I, Stone PH, Ikonomidis I, Alexopoulos D, Sabaté M. Recurrent atherosclerosis complications as a mechanism for stent failure. Hellenic J Cardiol. 2019 Apr 26. PMID: 31034959.
    Citations:    
  17. Stone PH, Fotiadis DI. Enhanced Multifactorial Biomechanical Stress Metrics to Predict Plaque Rupture: Rapid Assessment of Morphology and Plaque Structural Stress. JACC Cardiovasc Imaging. 2020 Mar; 13(3):817-819. PMID: 31005526.
    Citations:    
  18. Won KB, Lee SE, Lee BK, Park HB, Heo R, Rizvi A, Lin FY, Kumar A, Hadamitzky M, Kim YJ, Sung JM, Conte E, Andreini D, Pontone G, Budoff MJ, Gottlieb I, Chun EJ, Cademartiri F, Maffei E, Marques H, Leipsic JA, Shin S, Choi JH, Virmani R, Samady H, Chinnaiyan K, Raff GL, Stone PH, Berman DS, Narula J, Shaw LJ, Bax JJ, Min JK, Chang HJ. Longitudinal assessment of coronary plaque volume change related to glycemic status using serial coronary computed tomography angiography: A PARADIGM (Progression of AtheRosclerotic PlAque DetermIned by Computed TomoGraphic Angiography Imaging) substudy. J Cardiovasc Comput Tomogr. 2019 Mar - Apr; 13(2):142-147. PMID: 30580992.
    Citations:    Fields:    
  19. Siasos G, Tsigkou V, Zaromytidou M, Sara JD, Varshney A, Coskun AU, Lerman A, Stone PH. Role of local coronary blood flow patterns and shear stress on the development of microvascular and epicardial endothelial dysfunction and coronary plaque. Curr Opin Cardiol. 2018 11; 33(6):638-644. PMID: 30303854.
    Citations:    Fields:    
  20. Stone PH, Coskun AU, Croce KJ. Evolving insights into the role of local shear stress in late stent failure from neoatherosclerosis formation and plaque destabilization. Int J Cardiol. 2018 12 01; 272:45-46. PMID: 30126653.
    Citations:    Fields:    Translation:Humans
  21. Lee SE, Sung JM, Rizvi A, Lin FY, Kumar A, Hadamitzky M, Kim YJ, Conte E, Andreini D, Pontone G, Budoff MJ, Gottlieb I, Lee BK, Chun EJ, Cademartiri F, Maffei E, Marques H, Leipsic JA, Shin S, Hyun Choi J, Chinnaiyan K, Raff G, Virmani R, Samady H, Stone PH, Berman DS, Narula J, Shaw LJ, Bax JJ, Min JK, Chang HJ. Quantification of Coronary Atherosclerosis in the Assessment of Coronary Artery Disease. Circ Cardiovasc Imaging. 2018 07; 11(7):e007562. PMID: 30012825.
    Citations:    Fields:    
  22. Lee SE, Chang HJ, Sung JM, Park HB, Heo R, Rizvi A, Lin FY, Kumar A, Hadamitzky M, Kim YJ, Conte E, Andreini D, Pontone G, Budoff MJ, Gottlieb I, Lee BK, Chun EJ, Cademartiri F, Maffei E, Marques H, Leipsic JA, Shin S, Choi JH, Chinnaiyan K, Raff G, Virmani R, Samady H, Stone PH, Berman DS, Narula J, Shaw LJ, Bax JJ, Min JK. Effects of Statins on Coronary Atherosclerotic Plaques: The PARADIGM Study. JACC Cardiovasc Imaging. 2018 10; 11(10):1475-1484. PMID: 29909109.
    Citations: 1     Fields:    
  23. Chang HJ, Lin FY, Lee SE, Andreini D, Bax J, Cademartiri F, Chinnaiyan K, Chow BJW, Conte E, Cury RC, Feuchtner G, Hadamitzky M, Kim YJ, Leipsic J, Maffei E, Marques H, Plank F, Pontone G, Raff GL, van Rosendael AR, Villines TC, Weirich HG, Al'Aref SJ, Baskaran L, Cho I, Danad I, Han D, Heo R, Lee JH, Rivzi A, Stuijfzand WJ, Gransar H, Lu Y, Sung JM, Park HB, Berman DS, Budoff MJ, Samady H, Shaw LJ, Stone PH, Virmani R, Narula J, Min JK. Coronary Atherosclerotic Precursors of Acute Coronary Syndromes. J Am Coll Cardiol. 2018 06 05; 71(22):2511-2522. PMID: 29852975.
    Citations: 1     Fields:    
  24. Weir-McCall JR, Blanke P, Sellers SL, Ahmadi AA, Andreini D, Budoff MJ, Cademartiri F, Chinnaiyan K, Choi JH, Chun EJ, Conte E, Gottlieb I, Hadamitzky M, Kim YJ, Lee BK, Lee SE, Maffei E, Marques H, Pontone G, Raff GL, Shin S, Sung JM, Stone P, Samady H, Virmani R, Narula J, Berman DS, Shaw LJ, Bax JJ, Lin FY, Min JK, Chang HJ, Leipsic JA. Impact of Non-obstructive left main disease on the progression of coronary artery disease: A PARADIGM substudy. J Cardiovasc Comput Tomogr. 2018 May - Jun; 12(3):231-237. PMID: 29802032.
    Citations:    Fields:    Translation:Humans
  25. Kim U, Leipsic JA, Sellers SL, Shao M, Blanke P, Hadamitzky M, Kim YJ, Conte E, Andreini D, Pontone G, Budoff MJ, Gottlieb I, Lee BK, Chun EJ, Cademartiri F, Maffei E, Marques H, Shin S, Choi JH, Virmani R, Samady H, Stone PH, Berman DS, Narula J, Shaw LJ, Bax JJ, Min JK, Chang HJ. Natural History of Diabetic Coronary Atherosclerosis by Quantitative Measurement of Serial Coronary Computed Tomographic Angiography: Results of the PARADIGM Study. JACC Cardiovasc Imaging. 2018 10; 11(10):1461-1471. PMID: 29778853.
    Citations:    Fields:    
  26. Siasos G, Sara JD, Zaromytidou M, Park KH, Coskun AU, Lerman LO, Oikonomou E, Maynard CC, Fotiadis D, Stefanou K, Papafaklis M, Michalis L, Feldman C, Lerman A, Stone PH. Local Low Shear Stress and Endothelial Dysfunction in Patients With Nonobstructive Coronary Atherosclerosis. J Am Coll Cardiol. 2018 05 15; 71(19):2092-2102. PMID: 29747829.
    Citations:    Fields:    
  27. Antoniadis AP, Stone PH. Evolving understanding of the heterogeneous natural history of individual coronary artery plaques and the role of local endothelial shear stress. Curr Opin Cardiol. 2017 11; 32(6):748-754. PMID: 28841637.
    Citations:    Fields:    Translation:Humans
  28. Stone PH, Maehara A, Coskun AU, Maynard CC, Zaromytidou M, Siasos G, Andreou I, Fotiadis D, Stefanou K, Papafaklis M, Michalis L, Lansky AJ, Mintz GS, Serruys PW, Feldman CL, Stone GW. Role of Low Endothelial Shear Stress and Plaque Characteristics in the Prediction of Nonculprit Major Adverse Cardiac Events: The PROSPECT Study. JACC Cardiovasc Imaging. 2018 03; 11(3):462-471. PMID: 28917684.
    Citations:    Fields:    
  29. Yamamoto E, Siasos G, Zaromytidou M, Coskun AU, Xing L, Bryniarski K, Zanchin T, Sugiyama T, Lee H, Stone PH, Jang IK. Low Endothelial Shear Stress Predicts Evolution to High-Risk Coronary Plaque Phenotype in the Future: A Serial Optical Coherence Tomography and Computational Fluid Dynamics Study. Circ Cardiovasc Interv. 2017 Aug; 10(8). PMID: 28768758.
    Citations:    Fields:    Translation:Humans
  30. Stone PH. Ranolazine in Diabetics With Stable Ischemic Heart Disease: Greatest Efficacy Related to Greatest Metabolic Stress. J Am Coll Cardiol. 2017 05 09; 69(18):2314-2316. PMID: 28473137.
    Citations:    Fields:    
  31. Steinberg JS, Varma N, Cygankiewicz I, Aziz P, Balsam P, Baranchuk A, Cantillon DJ, Dilaveris P, Dubner SJ, El-Sherif N, Krol J, Kurpesa M, La Rovere MT, Lobodzinski SS, Locati ET, Mittal S, Olshansky B, Piotrowicz E, Saxon L, Stone PH, Tereshchenko L, Turitto G, Wimmer NJ, Verrier RL, Zareba W, Piotrowicz R. 2017 ISHNE-HRS expert consensus statement on ambulatory ECG and external cardiac monitoring/telemetry. Heart Rhythm. 2017 07; 14(7):e55-e96. PMID: 28495301.
    Citations: 2     Fields:    
  32. Shah NR, Cheezum MK, Veeranna V, Horgan SJ, Taqueti VR, Murthy VL, Foster C, Hainer J, Daniels KM, Rivero J, Shah AM, Stone PH, Morrow DA, Steigner ML, Dorbala S, Blankstein R, Di Carli MF. Ranolazine in Symptomatic Diabetic Patients Without Obstructive Coronary Artery Disease: Impact on Microvascular and Diastolic Function. J Am Heart Assoc. 2017 May 04; 6(5). PMID: 28473401.
    Citations:    Fields:    Translation:Humans
  33. Steinberg JS, Varma N, Cygankiewicz I, Aziz P, Balsam P, Baranchuk A, Cantillon DJ, Dilaveris P, Dubner SJ, El-Sherif N, Krol J, Kurpesa M, La Rovere MT, Lobodzinski SS, Locati ET, Mittal S, Olshansky B, Piotrowicz E, Saxon L, Stone PH, Tereshchenko L, Turakhia MP, Turitto G, Wimmer NJ, Verrier RL, Zareba W, Piotrowicz R. 2017 ISHNE-HRS expert consensus statement on ambulatory ECG and external cardiac monitoring/telemetry. Ann Noninvasive Electrocardiol. 2017 05; 22(3). PMID: 28480632.
    Citations: 1     Fields:    Translation:Humans
  34. Bourantas CV, Jaffer FA, Gijsen FJ, van Soest G, Madden SP, Courtney BK, Fard AM, Tenekecioglu E, Zeng Y, van der Steen AFW, Emelianov S, Muller J, Stone PH, Marcu L, Tearney GJ, Serruys PW. Hybrid intravascular imaging: recent advances, technical considerations, and current applications in the study of plaque pathophysiology. Eur Heart J. 2017 02 07; 38(6):400-412. PMID: 27118197.
    Citations: 12     Fields:    Translation:Humans
  35. Zaromytidou M, Antoniadis AP, Siasos G, Coskun AU, Andreou I, Papafaklis MI, Lucier M, Feldman CL, Stone PH. Heterogeneity of Coronary Plaque Morphology and Natural History: Current Understanding and Clinical Significance. Curr Atheroscler Rep. 2016 Dec; 18(12):80. PMID: 27822680.
    Citations: 2     Fields:    Translation:HumansAnimals
  36. Zaromytidou M, Siasos G, Coskun AU, Lucier M, Antoniadis AP, Papafaklis MI, Koskinas KC, Andreou I, Feldman CL, Stone PH. Intravascular hemodynamics and coronary artery disease: New insights and clinical implications. Hellenic J Cardiol. 2016 Nov - Dec; 57(6):389-400. PMID: 27894949.
    Citations: 1     Fields:    Translation:Humans
  37. Andreou I, Stone PH. In-Stent Atherosclerosis at a Crossroads: Neoatherosclerosis … or Paleoatherosclerosis? Circulation. 2016 11 08; 134(19):1413-1415. PMID: 27821417.
    Citations: 1     Fields:    Translation:Humans
  38. Stone PH, Coskun AU. Asymmetric Longitudinal Lesion Geometry: Expanding Clinical Applications of Biomechanics. JACC Cardiovasc Imaging. 2017 06; 10(6):689-691. PMID: 27665161.
    Citations:    Fields:    Translation:Humans
  39. Shishido K, Antoniadis AP, Takahashi S, Tsuda M, Mizuno S, Andreou I, Papafaklis MI, Coskun AU, O'Brien C, Feldman CL, Saito S, Edelman ER, Stone PH. Effects of Low Endothelial Shear Stress After Stent Implantation on Subsequent Neointimal Hyperplasia and Clinical Outcomes in Humans. J Am Heart Assoc. 2016 09 14; 5(9). PMID: 27628570.
    Citations:    Fields:    Translation:Humans
  40. Verjans JW, Osborn EA, Ughi GJ, Calfon Press MA, Hamidi E, Antoniadis AP, Papafaklis MI, Conrad MF, Libby P, Stone PH, Cambria RP, Tearney GJ, Jaffer FA. Targeted Near-Infrared Fluorescence Imaging of Atherosclerosis: Clinical and Intracoronary Evaluation of Indocyanine Green. JACC Cardiovasc Imaging. 2016 09; 9(9):1087-1095. PMID: 27544892.
    Citations: 9     Fields:    Translation:HumansAnimals
  41. Antoniadis AP, Papafaklis MI, Takahashi S, Shishido K, Andreou I, Chatzizisis YS, Tsuda M, Mizuno S, Makita Y, Domei T, Ikemoto T, Coskun AU, Honye J, Nakamura S, Saito S, Edelman ER, Feldman CL, Stone PH. Arterial Remodeling and Endothelial Shear Stress Exhibit Significant Longitudinal Heterogeneity Along the Length of Coronary Plaques. JACC Cardiovasc Imaging. 2016 08; 9(8):1007-9. PMID: 27491487.
    Citations: 1     Fields:    Translation:Humans
  42. Andreou I, Takahashi S, Tsuda M, Shishido K, Antoniadis AP, Papafaklis MI, Mizuno S, Coskun AU, Saito S, Feldman CL, Edelman ER, Stone PH. Atherosclerotic plaque behind the stent changes after bare-metal and drug-eluting stent implantation in humans: Implications for late stent failure? Atherosclerosis. 2016 09; 252:9-14. PMID: 27494445.
    Citations:    Fields:    Translation:Humans
  43. Stone PH, Coskun AU. Structural Stress of Coronary Plaques to Predict Risk for Clinical Events: New Biomechanical Modeling Frontiers Derived From Plaque Anatomy. Circ Cardiovasc Imaging. 2016 06; 9(6). PMID: 27307556.
    Citations:    Fields:    Translation:Humans
  44. May AM, Blackwell T, Stone PH, Stone KL, Cawthon PM, Sauer WH, Varosy PD, Redline S, Mehra R. Central Sleep-disordered Breathing Predicts Incident Atrial Fibrillation in Older Men. Am J Respir Crit Care Med. 2016 Apr 01; 193(7):783-91. PMID: 26595380.
    Citations: 8     Fields:    Translation:Humans
  45. Morbiducci U, Kok AM, Kwak BR, Stone PH, Steinman DA, Wentzel JJ. Atherosclerosis at arterial bifurcations: evidence for the role of haemodynamics and geometry. Thromb Haemost. 2016 Mar; 115(3):484-92. PMID: 26740210.
    Citations: 8     Fields:    Translation:HumansAnimals
  46. Deedwania PC, Stone PH, Fayyad RS, Laskey RE, Wilson DJ. Improvement in Renal Function and Reduction in Serum Uric Acid with Intensive Statin Therapy in Older Patients: A Post Hoc Analysis of the SAGE Trial. Drugs Aging. 2015 Dec; 32(12):1055-65. PMID: 26625880.
    Citations: 1     Fields:    Translation:Humans
  47. Antoniadis AP, Stone PH, Chatzizisis YS. Foretelling plaque disruption: Is the journey to Ithaca reaching destination? Atherosclerosis. 2016 Jan; 244:147-8. PMID: 26630183.
    Citations:    Fields:    Translation:Humans
  48. Stone PH, Coskun AU. Conceptual New Biomechanical Approaches to Identify Coronary Plaques at Risk of Disruption. JACC Cardiovasc Imaging. 2015 Oct; 8(10):1167-9. PMID: 26481841.
    Citations:    Fields:    Translation:Humans
  49. Papafaklis MI, Mizuno S, Takahashi S, Coskun AU, Antoniadis AP, Tsuda M, Feldman CL, Saito S, Stone PH. Incremental predictive value of combined endothelial shear stress, plaque necrotic core, and plaque burden for future cardiac events: A post-hoc analysis of the PREDICTION study. Int J Cardiol. 2016 Jan 01; 202:64-6. PMID: 26386924.
    Citations: 1     Fields:    Translation:Humans
  50. Papafaklis MI, Bourantas CV, Yonetsu T, Vergallo R, Kotsia A, Nakatani S, Lakkas LS, Athanasiou LS, Naka KK, Fotiadis DI, Feldman CL, Stone PH, Serruys PW, Jang IK, Michalis LK. Anatomically correct three-dimensional coronary artery reconstruction using frequency domain optical coherence tomographic and angiographic data: head-to-head comparison with intravascular ultrasound for endothelial shear stress assessment in humans. EuroIntervention. 2015 Aug; 11(4):407-15. PMID: 24974809.
    Citations: 5     Fields:    Translation:Humans
  51. Stone PH, Coskun AU, Prati F. Ongoing Methodological Approaches to Improve the In Vivo Assessment of Local Coronary Blood Flow and Endothelial Shear Stress: The Devil Is in the Details. J Am Coll Cardiol. 2015 Jul 14; 66(2):136-8. PMID: 26160629.
    Citations: 2     Fields:    Translation:Humans
  52. Siasos G, Oikonomou E, Zaromitidou M, Kioufis S, Kokkou E, Mourouzis K, Vlasis K, Vavuranakis M, Stone PH, Papavassiliou AG, Tousoulis D. Clopidogrel response variability is associated with endothelial dysfunction in coronary artery disease patients receiving dual antiplatelet therapy. Atherosclerosis. 2015 Sep; 242(1):102-8. PMID: 26188531.
    Citations: 1     Fields:    Translation:Humans
  53. Papafaklis MI, Takahashi S, Antoniadis AP, Coskun AU, Tsuda M, Mizuno S, Andreou I, Nakamura S, Makita Y, Hirohata A, Saito S, Feldman CL, Stone PH. Effect of the local hemodynamic environment on the de novo development and progression of eccentric coronary atherosclerosis in humans: insights from PREDICTION. Atherosclerosis. 2015 May; 240(1):205-11. PMID: 25801012.
    Citations: 11     Fields:    Translation:Humans
  54. Andreou I, Sun X, Stone PH, Edelman ER, Feinberg MW. miRNAs in atherosclerotic plaque initiation, progression, and rupture. Trends Mol Med. 2015 May; 21(5):307-18. PMID: 25771097.
    Citations: 19     Fields:    Translation:Humans
  55. Jia H, Hu S, Uemura S, Park SJ, Jang Y, Prasad A, Lee S, Soeda T, Abtahian F, Vergallo R, Tian J, Lee H, Stone PH, Yu B, Jang IK. Insights into the spatial distribution of lipid-rich plaques in relation to coronary artery bifurcations: an in-vivo optical coherence tomography study. Coron Artery Dis. 2015 Mar; 26(2):133-41. PMID: 25356817.
    Citations: 1     Fields:    Translation:Humans
  56. Braverman AC, Mesana T, Stone PH. Editorial introductions. Curr Opin Cardiol. 2014 Nov; 29(6):v-vi. PMID: 25286375.
    Citations:    
  57. Andreou I, Antoniadis AP, Shishido K, Papafaklis MI, Koskinas KC, Chatzizisis YS, Coskun AU, Edelman ER, Feldman CL, Stone PH. How do we prevent the vulnerable atherosclerotic plaque from rupturing? Insights from in vivo assessments of plaque, vascular remodeling, and local endothelial shear stress. J Cardiovasc Pharmacol Ther. 2015 May; 20(3):261-75. PMID: 25336461.
    Citations: 7     Fields:    Translation:HumansCells
  58. Vergallo R, Papafaklis MI, Yonetsu T, Bourantas CV, Andreou I, Wang Z, Fujimoto JG, McNulty I, Lee H, Biasucci LM, Crea F, Feldman CL, Michalis LK, Stone PH, Jang IK. Endothelial shear stress and coronary plaque characteristics in humans: combined frequency-domain optical coherence tomography and computational fluid dynamics study. Circ Cardiovasc Imaging. 2014 Nov; 7(6):905-11. PMID: 25190591.
    Citations: 14     Fields:    Translation:Humans
  59. Zanobetti A, Luttmann-Gibson H, Horton ES, Cohen A, Coull BA, Hoffmann B, Schwartz JD, Mittleman MA, Li Y, Stone PH, de Souza C, Lamparello B, Koutrakis P, Gold DR. Brachial artery responses to ambient pollution, temperature, and humidity in people with type 2 diabetes: a repeated-measures study. Environ Health Perspect. 2014 Mar; 122(3):242-8. PMID: 24398072.
    Citations: 12     Fields:    Translation:HumansPHPublic Health
  60. Koskinas KC, Chatzizisis YS, Papafaklis MI, Coskun AU, Baker AB, Jarolim P, Antoniadis A, Edelman ER, Stone PH, Feldman CL. Synergistic effect of local endothelial shear stress and systemic hypercholesterolemia on coronary atherosclerotic plaque progression and composition in pigs. Int J Cardiol. 2013 Nov 30; 169(6):394-401. PMID: 24148915.
    Citations: 5     Fields:    Translation:Animals
  61. Bourantas CV, Papafaklis MI, Athanasiou L, Kalatzis FG, Naka KK, Siogkas PK, Takahashi S, Saito S, Fotiadis DI, Feldman CL, Stone PH, Michalis LK. A new methodology for accurate 3-dimensional coronary artery reconstruction using routine intravascular ultrasound and angiographic data: implications for widespread assessment of endothelial shear stress in humans. EuroIntervention. 2013 Sep; 9(5):582-93. PMID: 23608530.
    Citations: 8     Fields:    Translation:Humans
  62. Wimmer NJ, Scirica BM, Stone PH. The clinical significance of continuous ECG (ambulatory ECG or Holter) monitoring of the ST-segment to evaluate ischemia: a review. Prog Cardiovasc Dis. 2013 Sep-Oct; 56(2):195-202. PMID: 24215751.
    Citations: 1     Fields:    Translation:Humans
  63. Koskinas KC, Sukhova GK, Baker AB, Papafaklis MI, Chatzizisis YS, Coskun AU, Quillard T, Jonas M, Maynard C, Antoniadis AP, Shi GP, Libby P, Edelman ER, Feldman CL, Stone PH. Thin-capped atheromata with reduced collagen content in pigs develop in coronary arterial regions exposed to persistently low endothelial shear stress. Arterioscler Thromb Vasc Biol. 2013 Jul; 33(7):1494-504. PMID: 23640495.
    Citations: 13     Fields:    Translation:AnimalsCells
  64. Sakamoto S, Takahashi S, Coskun AU, Papafaklis MI, Takahashi A, Saito S, Stone PH, Feldman CL. Relation of distribution of coronary blood flow volume to coronary artery dominance. Am J Cardiol. 2013 May 15; 111(10):1420-4. PMID: 23540543.
    Citations: 6     Fields:    Translation:Humans
  65. Stone PH. Ischemia dictates outcome, not symptoms. J Am Coll Cardiol. 2013 Feb 19; 61(7):712-3. PMID: 23410542.
    Citations: 1     Fields:    Translation:Humans
  66. Wimmer NJ, Stone PH. Anti-anginal and anti-ischemic effects of late sodium current inhibition. Cardiovasc Drugs Ther. 2013 Feb; 27(1):69-77. PMID: 23247666.
    Citations: 2     Fields:    Translation:Humans
  67. Wentzel JJ, Chatzizisis YS, Gijsen FJ, Giannoglou GD, Feldman CL, Stone PH. Endothelial shear stress in the evolution of coronary atherosclerotic plaque and vascular remodelling: current understanding and remaining questions. Cardiovasc Res. 2012 Nov 01; 96(2):234-43. PMID: 22752349.
    Citations: 34     Fields:    Translation:HumansAnimals
  68. Stone PH, Saito S, Takahashi S, Makita Y, Nakamura S, Kawasaki T, Takahashi A, Katsuki T, Nakamura S, Namiki A, Hirohata A, Matsumura T, Yamazaki S, Yokoi H, Tanaka S, Otsuji S, Yoshimachi F, Honye J, Harwood D, Reitman M, Coskun AU, Papafaklis MI, Feldman CL. Prediction of progression of coronary artery disease and clinical outcomes using vascular profiling of endothelial shear stress and arterial plaque characteristics: the PREDICTION Study. Circulation. 2012 Jul 10; 126(2):172-81. PMID: 22723305.
    Citations: 67     Fields:    Translation:Humans
  69. Takahashi S, Papafaklis MI, Sakamoto S, Antoniadis AP, Coskun AU, Feldman CL, Stone PH. The effect of statins on high-risk atherosclerotic plaque associated with low endothelial shear stress. Curr Opin Lipidol. 2011 Oct; 22(5):358-64. PMID: 21841484.
    Citations: 1     Fields:    Translation:HumansAnimals
  70. Stone PH, Feldman CL. In vivo assessment of the risk profile of evolving individual coronary plaques: a step closer. Circulation. 2011 Aug 16; 124(7):763-5. PMID: 21844087.
    Citations:    Fields:    Translation:AnimalsCells
  71. Stone PH. Allopurinol a new anti-ischemic role for an old drug. J Am Coll Cardiol. 2011 Aug 16; 58(8):829-30. PMID: 21835318.
    Citations: 8     Fields:    Translation:Humans
  72. Doorey A, Denenberg B, Sagar V, Hanna T, Newman J, Stone PH. Comparison of myocardial ischemia during intense mental stress using flight simulation in airline pilots with coronary artery disease to that produced with conventional mental and treadmill exercise stress testing. Am J Cardiol. 2011 Sep 01; 108(5):651-7. PMID: 21723529.
    Citations: 1     Fields:    Translation:Humans
  73. Chatzizisis YS, Baker AB, Sukhova GK, Koskinas KC, Papafaklis MI, Beigel R, Jonas M, Coskun AU, Stone BV, Maynard C, Shi GP, Libby P, Feldman CL, Edelman ER, Stone PH. Augmented expression and activity of extracellular matrix-degrading enzymes in regions of low endothelial shear stress colocalize with coronary atheromata with thin fibrous caps in pigs. Circulation. 2011 Feb 15; 123(6):621-30. PMID: 21282495.
    Citations: 29     Fields:    Translation:AnimalsCells
  74. Szumita PM, Baroletti S, Avery KR, Massaro AF, Hou PC, Pierce CD, Henderson GV, Stone PH, Scirica BM. Implementation of a Hospital-wide Protocol for Induced Hypothermia Following Successfully Resuscitated Cardiac Arrest. Crit Pathw Cardiol. 2010 Dec; 9(4):216-20. PMID: 21119341.
    Citations: 3     Fields:    Translation:Humans
  75. Papafaklis MI, Koskinas KC, Chatzizisis YS, Stone PH, Feldman CL. In-vivo assessment of the natural history of coronary atherosclerosis: vascular remodeling and endothelial shear stress determine the complexity of atherosclerotic disease progression. Curr Opin Cardiol. 2010 Nov; 25(6):627-38. PMID: 20838338.
    Citations: 10     Fields:    Translation:Humans
  76. Stone PH, Feldman CL. In vivo assessment of local intravascular hemodynamics and arterial morphology to investigate vascular outcomes: a growing field coming of age. JACC Cardiovasc Interv. 2010 Nov; 3(11):1199-201. PMID: 21087757.
    Citations: 2     Fields:    Translation:Humans
  77. Baker AB, Chatzizisis YS, Beigel R, Jonas M, Stone BV, Coskun AU, Maynard C, Rogers C, Koskinas KC, Feldman CL, Stone PH, Edelman ER. Regulation of heparanase expression in coronary artery disease in diabetic, hyperlipidemic swine. Atherosclerosis. 2010 Dec; 213(2):436-42. PMID: 20950809.
    Citations: 16     Fields:    Translation:Animals
  78. Stone PH, Chaitman BR, Stocke K, Sano J, DeVault A, Koch GG. The anti-ischemic mechanism of action of ranolazine in stable ischemic heart disease. J Am Coll Cardiol. 2010 Sep 14; 56(12):934-42. PMID: 20828645.
    Citations: 14     Fields:    Translation:Humans
  79. Luttmann-Gibson H, Suh HH, Coull BA, Dockery DW, Sarnat SE, Schwartz J, Stone PH, Gold DR. Systemic inflammation, heart rate variability and air pollution in a cohort of senior adults. Occup Environ Med. 2010 Sep; 67(9):625-30. PMID: 20519749.
    Citations: 18     Fields:    Translation:HumansPHPublic Health
  80. Koskinas KC, Feldman CL, Chatzizisis YS, Coskun AU, Jonas M, Maynard C, Baker AB, Papafaklis MI, Edelman ER, Stone PH. Natural history of experimental coronary atherosclerosis and vascular remodeling in relation to endothelial shear stress: a serial, in vivo intravascular ultrasound study. Circulation. 2010 May 18; 121(19):2092-101. PMID: 20439786.
    Citations: 36     Fields:    Translation:Animals
  81. Zanobetti A, Gold DR, Stone PH, Suh HH, Schwartz J, Coull BA, Speizer FE. Reduction in heart rate variability with traffic and air pollution in patients with coronary artery disease. Environ Health Perspect. 2010 Mar; 118(3):324-30. PMID: 20064780.
    Citations: 34     Fields:    Translation:Humans
  82. Stone PH. Current selection of optimal prosthetic aortic valve replacement in middle-aged patients: still dealer's choice. J Am Coll Cardiol. 2009 Nov 10; 54(20):1869-71. PMID: 19892238.
    Citations:    Fields:    Translation:Humans
  83. Koskinas KC, Chatzizisis YS, Baker AB, Edelman ER, Stone PH, Feldman CL. The role of low endothelial shear stress in the conversion of atherosclerotic lesions from stable to unstable plaque. Curr Opin Cardiol. 2009 Nov; 24(6):580-90. PMID: 19809311.
    Citations: 13     Fields:    Translation:Humans
  84. Ramkumar PG, Mitsouras D, Feldman CL, Stone PH, Rybicki FJ. New advances in cardiac computed tomography. Curr Opin Cardiol. 2009 Nov; 24(6):596-603. PMID: 19752727.
    Citations: 8     Fields:    Translation:Humans
  85. Francis JL, Weinstein AA, Krantz DS, Haigney MC, Stein PK, Stone PH, Gottdiener JS, Kop WJ. Association between symptoms of depression and anxiety with heart rate variability in patients with implantable cardioverter defibrillators. Psychosom Med. 2009 Oct; 71(8):821-7. PMID: 19661191.
    Citations: 11     Fields:    Translation:Humans
  86. Zanobetti A, Stone PH, Speizer FE, Schwartz JD, Coull BA, Suh HH, Nearing BD, Mittleman MA, Verrier RL, Gold DR. T-wave alternans, air pollution and traffic in high-risk subjects. Am J Cardiol. 2009 Sep 01; 104(5):665-70. PMID: 19699342.
    Citations: 14     Fields:    Translation:HumansPHPublic Health
  87. Gibson CM, Pride YB, Buros JL, Ciaglo LN, Morrow DA, Scirica BM, Stone PH. Timing and duration of myocardial ischemia on Holter monitoring following percutaneous coronary intervention and their association with clinical outcomes (a PROTECT-TIMI 30 Substudy Analysis). Am J Cardiol. 2009 Jul 01; 104(1):36-40. PMID: 19576318.
    Citations: 1     Fields:    Translation:Humans
  88. Scirica BM, Morrow DA, Budaj A, Dalby AJ, Mohanavelu S, Qin J, Aroesty J, Hedgepeth CM, Stone PH, Braunwald E. Ischemia detected on continuous electrocardiography after acute coronary syndrome: observations from the MERLIN-TIMI 36 (Metabolic Efficiency With Ranolazine for Less Ischemia in Non-ST-Elevation Acute Coronary Syndrome-Thrombolysis In Myocardial Infarction 36) trial. J Am Coll Cardiol. 2009 Apr 21; 53(16):1411-21. PMID: 19371824.
    Citations: 6     Fields:    Translation:Humans
  89. Syed Z, Scirica BM, Mohanavelu S, Sung P, Michelson EL, Cannon CP, Stone PH, Stultz CM, Guttag JV. Relation of death within 90 days of non-ST-elevation acute coronary syndromes to variability in electrocardiographic morphology. Am J Cardiol. 2009 Feb 01; 103(3):307-11. PMID: 19166680.
    Citations: