Harvard Catalyst Profiles

Contact, publication, and social network information about Harvard faculty and fellows.

Frederick W. Alt, Ph.D.

Co-Author

This page shows the publications co-authored by Frederick Alt and Raul Mostoslavsky.
Connection Strength

1.500
  1. Genomic instability and aging-like phenotype in the absence of mammalian SIRT6. Cell. 2006 Jan 27; 124(2):315-29.
    View in: PubMed
    Score: 0.334
  2. Receptor revision in T cells: an open question? Trends Immunol. 2004 Jun; 25(6):276-9.
    View in: PubMed
    Score: 0.298
  3. Vbeta cluster sequences reduce the frequency of primary Vbeta2 and Vbeta14 rearrangements. Eur J Immunol. 2008 Sep; 38(9):2564-72.
    View in: PubMed
    Score: 0.100
  4. SIRT6 in DNA repair, metabolism and ageing. J Intern Med. 2008 Feb; 263(2):128-41.
    View in: PubMed
    Score: 0.096
  5. Mechanism and control of V(D)J recombination at the immunoglobulin heavy chain locus. Annu Rev Immunol. 2006; 24:541-70.
    View in: PubMed
    Score: 0.083
  6. Mammalian SIRT1 limits replicative life span in response to chronic genotoxic stress. Cell Metab. 2005 Jul; 2(1):67-76.
    View in: PubMed
    Score: 0.080
  7. DNA repair, genome stability, and aging. Cell. 2005 Feb 25; 120(4):497-512.
    View in: PubMed
    Score: 0.078
  8. The lingering enigma of the allelic exclusion mechanism. Cell. 2004 Sep 03; 118(5):539-44.
    View in: PubMed
    Score: 0.076
  9. Chromatin dynamics and locus accessibility in the immune system. Nat Immunol. 2003 Jul; 4(7):603-6.
    View in: PubMed
    Score: 0.070
  10. SIRT7 represses Myc activity to suppress ER stress and prevent fatty liver disease. Cell Rep. 2013 Nov 14; 5(3):654-665.
    View in: PubMed
    Score: 0.036
  11. Intracellular NAD levels regulate tumor necrosis factor protein synthesis in a sirtuin-dependent manner. Nat Med. 2009 Feb; 15(2):206-10.
    View in: PubMed
    Score: 0.026
  12. SIRT1 redistribution on chromatin promotes genomic stability but alters gene expression during aging. Cell. 2008 Nov 28; 135(5):907-18.
    View in: PubMed
    Score: 0.025
  13. SIRT1 regulates circadian clock gene expression through PER2 deacetylation. Cell. 2008 Jul 25; 134(2):317-28.
    View in: PubMed
    Score: 0.025
  14. A role for the NAD-dependent deacetylase Sirt1 in the regulation of autophagy. Proc Natl Acad Sci U S A. 2008 Mar 04; 105(9):3374-9.
    View in: PubMed
    Score: 0.024
  15. SIRT1 controls endothelial angiogenic functions during vascular growth. Genes Dev. 2007 Oct 15; 21(20):2644-58.
    View in: PubMed
    Score: 0.023
  16. Mammalian Sir2 homolog SIRT3 regulates global mitochondrial lysine acetylation. Mol Cell Biol. 2007 Dec; 27(24):8807-14.
    View in: PubMed
    Score: 0.023
  17. Allelic 'choice' governs somatic hypermutation in vivo at the immunoglobulin kappa-chain locus. Nat Immunol. 2007 Jul; 8(7):715-22.
    View in: PubMed
    Score: 0.023
  18. Metabolic control of muscle mitochondrial function and fatty acid oxidation through SIRT1/PGC-1alpha. EMBO J. 2007 Apr 04; 26(7):1913-23.
    View in: PubMed
    Score: 0.023
  19. SIRT4 inhibits glutamate dehydrogenase and opposes the effects of calorie restriction in pancreatic beta cells. Cell. 2006 Sep 08; 126(5):941-54.
    View in: PubMed
    Score: 0.022
  20. Stress-dependent regulation of FOXO transcription factors by the SIRT1 deacetylase. Science. 2004 Mar 26; 303(5666):2011-5.
    View in: PubMed
    Score: 0.018
  21. Developmental defects and p53 hyperacetylation in Sir2 homolog (SIRT1)-deficient mice. Proc Natl Acad Sci U S A. 2003 Sep 16; 100(19):10794-9.
    View in: PubMed
    Score: 0.018
Connection Strength
The connection strength for co-authors is the sum of the scores for each of their shared publications.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.
Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.