Victor H. Gerbaudo, Ph.D.
|Title||Assistant Professor of Radiology|
|Institution||Brigham and Women's Hospital|
|Address||Brigham and Women's Hospital|
75 Francis St
Boston MA 02115
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|2000||Madame Curie Radiologic Science Lecturer|
|2001||Partners in Excellence Award in Leadership and Innovation|
|2003||Radiology Department Team Award|
|2004||Award of Merit, American Roentgen Ray Society|
|2004||3rd Place, Best Paper of the Year Award, SNM|
|2007||Partners in Excellence Team Award: Cyclotron Project|
|2008||Partners in Excellence Team Award: Shapiro Cardiovascular Center Working Group|
|2008||Partners in Excellence Team Award: Electronic Signature Project|
|2012||Cum Laude Award, Radiological Society of North America |
|2013||One of 3 Best Papers of the Year Award, SNM|
|2014||Opening Plenary Speaker, World Federation of Nuclear Medicine & Biology Congress|
Dr Gerbaudo is the Senior Director of Nuclear Medicine, Molecular Imaging and Noninvasive Cardiovascular Imaging Administration, and the Associate Scientific Director of the Advanced Multimodality Image Guided Operating Suite (AMIGO) in the Department of Radiology at the Brigham and Women’s Hospital, Harvard Medical School. He is a clinical Nuclear Oncology scientist with more than 20 years of experience in the field. His clinical, teaching and research efforts focus on the in-vivo qualitative and quantitative monitoring of tumor biology, imaging, and response to therapy with PET/CT.
Specific Academic Interests:
• Molecular biomarkers as predictors of clinical outcome in cancer patients
• Correlation between molecular biomarkers and medical imaging signatures
• PET Imaging-based phenotyping of thoracic malignancies
• Molecular imaging as a biomarker to non-invasively direct and monitor response to cancer therapy
Gerbaudo's teaching integrates the application of basic concepts of tumor pathophysiology and molecular pathology to oncologic imaging, and to the interpretation and integration of imaging results into management decisions. Gerbaudo teaches Oncologic Nuclear Medicine, including both the clinical use of Gamma and Positron imaging (PET). Topics of interest include molecular imaging of tumor cell proliferation, perfusion, hypoxia and glycolytic metabolism. His audience is comprised of physician specialists, medical students, residents, research and clinical postdoctoral fellows, doctoral students, and technologists. His teaching topics include: 1) the application of basic concepts of tumor pathophysiology and molecular pathology to Oncologic imaging; 2) the review of the basic aspects of imaging instrumentation, and radiotracers used in Nuclear Oncology; 4) interpretation of imaging findings and their contribution to risk-adapted therapy and drug design; 5) the imaging and quantification of relevant tumoral processes such as proliferation, hypoxia, apoptosis and metabolism with PET/CT, and 6) research methodology, journal club, and the preparation of scholarly publication material.
Clinical and Research Interests:
Gerbaudo's clinical interests focus on the assessment and characterization of tumor invasion and metastasis with positron imaging of thoracic malignancies (i.e., malignant pleural mesothelioma, lung cancer), as well as esophageal cancer, brain and gastrointestinal tumors. His work in this area has expanded the use of clinical PET/CT for metabolically guided tumor biopsy and ablation, and for metabolic grading and staging of human tumors, as it relates to histological grade, molecular pathology, surgical stage and survival.
As a health care administrator, he is responsible for the overall operational effectiveness, patient experience, and financial health of the Brigham and Women’s Hospital Molecular Imaging service (Nuclear Medicine & PET, Radiopharmacy, Biomedical Imaging Core, AMIGO PET/CT), and of its Noninvasive Cardiovascular Imaging Program and the Cardiac Stress laboratory.
Gerbaudo's research activities include: 1) the anatomo-metabolic assessment of tumor aggressiveness in Malignant Pleural Mesothelioma, lung cancer, esophageal cancer and other thoracic tumors; 2) FDG and FLT imaging for the quantitative in-vivo functional characterization of tumor invasion and metastasis, and for the assessment of response early during the course of cancer therapy; 3) the study of the underlying molecular mechanisms associated with changes in dynamic properties of different PET probes with disease progression, and with the effect of chemotherapy on brain metabolism; 4) the use of PET/CT imaging for biopsy targeting in order to decrease sampling errors, for guiding tumor ablation, and to improve the accuracy of gross tumor volume definition during radiotherapy planning, and 5) in-vivo anatomo-metabolic tumor volume estimation as it relates to histological grade, proliferative potential, molecular pathology, surgical stage, response to cytotoxic and cytostatic therapies, and to survival.
o Nuclear Medicine Imaging Science, Nuclear Medicine Physics and Instrumentation,
Radioimmunoassay and Radiotracers, Los Angeles City College with clinical rotations at Holy
Cross Medical Center, VA West Los Angeles Medical Center and UCLA Medical Center, 1983
o Health Sciences, University of Redlands, 1984
o Clinical Nuclear Medicine and PET Imaging Science, UCLA School of Medicine, 1994
o Medicine, University of Buenos Aires School of Medicine, Argentina, 1995-1999
o Nuclear Oncology and Therapy, University of Miami School of Medicine, 2000
o Health Care Administration, University of Maryland University College, 2012
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