Harvard Catalyst Profiles

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Tianxi Cai

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Research
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. R01GM079330 (CAI, TIANXI) Jun 1, 2007 - Jun 30, 2015
    NIH/NIGMS
    Robust Approaches to the Development and Evaluation of Prognostic Classifiers
    Role: Principal Investigator

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Zhong QY, Gelaye B, Karlson EW, Avillach P, Smoller JW, Cai T, Williams MA. Associations of antepartum suicidal behaviour with adverse infant and obstetric outcomes. Paediatr Perinat Epidemiol. 2019 Feb 20. PMID: 30790331.
    Citations:    
  2. Ning W, Chan S, Beam A, Yu M, Geva A, Liao K, Mullen M, Mandl KD, Kohane I, Cai T, Yu S. Feature extraction for phenotyping from semantic and knowledge resources. J Biomed Inform. 2019 Mar; 91:103122. PMID: 30738949.
    Citations:    
  3. Hejblum BP, Weber GM, Liao KP, Palmer NP, Churchill S, Shadick NA, Szolovits P, Murphy SN, Kohane IS, Cai T. Probabilistic record linkage of de-identified research datasets with discrepancies using diagnosis codes. Sci Data. 2019 01 08; 6:180298. PMID: 30620344.
    Citations:    Fields:    
  4. Jorge A, Castro VM, Barnado A, Gainer V, Hong C, Cai T, Cai T, Carroll R, Denny JC, Crofford L, Costenbader KH, Liao KP, Karlson EW, Feldman CH. Identifying lupus patients in electronic health records: Development and validation of machine learning algorithms and application of rule-based algorithms. Semin Arthritis Rheum. 2019 Jan 04. PMID: 30665626.
    Citations:    Fields:    
  5. Zhong QY, Mittal LP, Nathan MD, Brown KM, Knudson González D, Cai T, Finan S, Gelaye B, Avillach P, Smoller JW, Karlson EW, Cai T, Williams MA. Use of natural language processing in electronic medical records to identify pregnant women with suicidal behavior: towards a solution to the complex classification problem. Eur J Epidemiol. 2019 Feb; 34(2):153-162. PMID: 30535584.
    Citations:    Fields:    
  6. Furtado JD, Yamamoto R, Melchior JT, Andraski AB, Gamez-Guerrero M, Mulcahy P, He Z, Cai T, Davidson WS, Sacks FM. Distinct Proteomic Signatures in 16 HDL (High-Density Lipoprotein) Subspecies. Arterioscler Thromb Vasc Biol. 2018 Dec; 38(12):2827-2842. PMID: 30571168.
    Citations:    Fields:    
  7. Goodman MO, Chibnik L, Cai T. Variance components genetic association test for zero-inflated count outcomes. Genet Epidemiol. 2019 02; 43(1):82-101. PMID: 30353568.
    Citations:    Fields:    
  8. Gronsbell J, Minnier J, Yu S, Liao K, Cai T. Automated Feature Selection of Predictors in Electronic Medical Records Data. Biometrics. 2018 Oct 24. PMID: 30353541.
    Citations:    Fields:    
  9. Imran TF, Posner D, Honerlaw J, Vassy JL, Song RJ, Ho YL, Kittner SJ, Liao KP, Cai T, O'Donnell CJ, Djousse L, Gagnon DR, Gaziano JM, Wilson PW, Cho K. A phenotyping algorithm to identify acute ischemic stroke accurately from a national biobank: the Million Veteran Program. Clin Epidemiol. 2018; 10:1509-1521. PMID: 30425582.
    Citations:    
  10. Hong C, Liao KP, Cai T. Semi-supervised validation of multiple surrogate outcomes with application to electronic medical records phenotyping. Biometrics. 2018 Sep 29. PMID: 30267536.
    Citations:    Fields:    
  11. Can A, Castro VM, Dligach D, Finan S, Yu S, Gainer V, Shadick NA, Savova G, Murphy S, Cai T, Weiss ST, Du R. Elevated International Normalized Ratio Is Associated With Ruptured Aneurysms. Stroke. 2018 Sep; 49(9):2046-2052. PMID: 30354989.
    Citations:    Fields:    
  12. Cai T, Zhang Y, Ho YL, Link N, Sun J, Huang J, Cai TA, Damrauer S, Ahuja Y, Honerlaw J, Huang J, Costa L, Schubert P, Hong C, Gagnon D, Sun YV, Gaziano JM, Wilson P, Cho K, Tsao P, O'Donnell CJ, Liao KP. Association of Interleukin 6 Receptor Variant With Cardiovascular Disease Effects of Interleukin 6 Receptor Blocking Therapy: A Phenome-Wide Association Study. JAMA Cardiol. 2018 Sep 01; 3(9):849-857. PMID: 30090940.
    Citations:    Fields:    
  13. Can A, Rudy RF, Castro VM, Yu S, Dligach D, Finan S, Gainer V, Shadick NA, Savova G, Murphy S, Cai T, Weiss ST, Du R. Association between aspirin dose and subarachnoid hemorrhage from saccular aneurysms: A case-control study. Neurology. 2018 Sep 18; 91(12):e1175-e1181. PMID: 30135253.
    Citations:    Fields:    
  14. Zhang J, Can A, Mukundan S, Steigner M, Castro VM, Dligach D, Finan S, Yu S, Gainer V, Shadick NA, Savova G, Murphy S, Cai T, Wang Z, Weiss ST, Du R. Morphological Variables Associated With Ruptured Middle Cerebral Artery Aneurysms. Neurosurgery. 2018 May 30. PMID: 29850834.
    Citations:    Fields:    
  15. Zhong QY, Karlson EW, Gelaye B, Finan S, Avillach P, Smoller JW, Cai T, Williams MA. Screening pregnant women for suicidal behavior in electronic medical records: diagnostic codes vs. clinical notes processed by natural language processing. BMC Med Inform Decis Mak. 2018 05 29; 18(1):30. PMID: 29843698.
    Citations:    Fields:    
  16. Can A, Rudy RF, Castro VM, Dligach D, Finan S, Yu S, Gainer V, Shadick NA, Savova G, Murphy S, Cai T, Weiss ST, Du R. Low Serum Calcium and Magnesium Levels and Rupture of Intracranial Aneurysms. Stroke. 2018 Jul; 49(7):1747-1750. PMID: 29844027.
    Citations: 1     Fields:    
  17. Hejblum BP, Cui J, Lahey LJ, Cagan A, Sparks JA, Sokolove J, Cai T, Liao KP. Association Between Anti-Citrullinated Fibrinogen Antibodies and Coronary Artery Disease in Rheumatoid Arthritis. Arthritis Care Res (Hoboken). 2018 Jul; 70(7):1113-1117. PMID: 28992379.
    Citations:    Fields:    
  18. Chen CY, Lee PH, Castro VM, Minnier J, Charney AW, Stahl EA, Ruderfer DM, Murphy SN, Gainer V, Cai T, Jones I, Pato CN, Pato MT, Landén M, Sklar P, Perlis RH, Smoller JW. Genetic validation of bipolar disorder identified by automated phenotyping using electronic health records. Transl Psychiatry. 2018 04 18; 8(1):86. PMID: 29666432.
    Citations: 1     Fields:    Translation:Humans
  19. Maziarz M, Cai T, Qi L, Lok AS, Zheng Y. Evaluating longitudinal markers under two-phase study designs. Biostatistics. 2018 Apr 18. PMID: 29912281.
    Citations:    Fields:    
  20. Sinnott JA, Cai T. Pathway aggregation for survival prediction via multiple kernel learning. Stat Med. 2018 Jul 20; 37(16):2501-2515. PMID: 29664143.
    Citations: 1     Fields:    
  21. Can A, Castro VM, Dligach D, Finan S, Yu S, Gainer V, Shadick NA, Savova G, Murphy S, Cai T, Weiss ST, Du R. Lipid-Lowering Agents and High HDL (High-Density Lipoprotein) Are Inversely Associated With Intracranial Aneurysm Rupture. Stroke. 2018 May; 49(5):1148-1154. PMID: 29622625.
    Citations:    Fields:    
  22. McCoy TH, Castro VM, Hart KL, Pellegrini AM, Yu S, Cai T, Perlis RH. Genome-wide Association Study of Dimensional Psychopathology Using Electronic Health Records. Biol Psychiatry. 2018 Jun 15; 83(12):1005-1011. PMID: 29496196.
    Citations: 1     Fields:    
  23. McCoy TH, Yu S, Hart KL, Castro VM, Brown HE, Rosenquist JN, Doyle AE, Vuijk PJ, Cai T, Perlis RH. High Throughput Phenotyping for Dimensional Psychopathology in Electronic Health Records. Biol Psychiatry. 2018 Jun 15; 83(12):997-1004. PMID: 29496195.
    Citations: 1     Fields:    
  24. Qian B, Rudy RF, Cai T, Du R. Cerebral Artery Diameter in Inbred Mice Varies as a Function of Strain. Front Neuroanat. 2018; 12:10. PMID: 29515376.
    Citations:    
  25. Zhong QY, Gelaye B, Smoller JW, Avillach P, Cai T, Williams MA. Adverse obstetric outcomes during delivery hospitalizations complicated by suicidal behavior among US pregnant women. PLoS One. 2018; 13(2):e0192943. PMID: 29447245.
    Citations:    Fields:    Translation:Humans
  26. Yu S, Ma Y, Gronsbell J, Cai T, Ananthakrishnan AN, Gainer VS, Churchill SE, Szolovits P, Murphy SN, Kohane IS, Liao KP, Cai T. Enabling phenotypic big data with PheNorm. J Am Med Inform Assoc. 2018 01 01; 25(1):54-60. PMID: 29126253.
    Citations: 2     Fields:    Translation:Humans
  27. Aghayev A, Giannopoulos AA, Gronsbell J, George E, Cai T, Steigner ML, Mitsouras D, Rybicki FJ. Common First-Pass CT Angiography Findings Associated With Rapid Growth Rate in Abdominal Aorta Aneurysms Between 3 and 5 cm in Largest Diameter. AJR Am J Roentgenol. 2018 Feb; 210(2):431-437. PMID: 29261347.
    Citations:    Fields:    Translation:Humans
  28. Can A, Castro VM, Yu S, Dligach D, Finan S, Gainer VS, Shadick NA, Savova G, Murphy S, Cai T, Weiss ST, Du R. Antihyperglycemic Agents Are Inversely Associated With Intracranial Aneurysm Rupture. Stroke. 2018 01; 49(1):34-39. PMID: 29203688.
    Citations:    Fields:    Translation:Humans
  29. Zhou QM, Dai W, Zheng Y, Cai T. Robust Dynamic Risk Prediction with Longitudinal Studies. Stat Theory Relat Fields. 2017; 1(2):159-170. PMID: 29335682.
    Citations:    
  30. Can A, Castro VM, Ozdemir YH, Dagen S, Dligach D, Finan S, Yu S, Gainer V, Shadick NA, Savova G, Murphy S, Cai T, Weiss ST, Du R. Heroin Use Is Associated with Ruptured Saccular Aneurysms. Transl Stroke Res. 2018 08; 9(4):340-346. PMID: 29103103.
    Citations: 3     Fields:    Translation:Humans
  31. Wang X, Zhang Z, Morris N, Cai T, Lee S, Wang C, Yu TW, Walsh CA, Lin X. Rare variant association test in family-based sequencing studies. Brief Bioinform. 2017 Nov 01; 18(6):954-961. PMID: 27677958.
    Citations: 1     Fields:    Translation:Humans
  32. Xia Y, Cai T, Cai TT. Multiple Testing of Submatrices of a Precision Matrix with Applications to Identification of Between Pathway Interactions. J Am Stat Assoc. 2018; 113(521):328-339. PMID: 29881130.
    Citations:    
  33. Aroner SA, Yang M, Li J, Furtado JD, Sacks FM, Tjønneland A, Overvad K, Cai T, Jensen MK. Apolipoprotein C-III and High-Density Lipoprotein Subspecies Defined by Apolipoprotein C-III in Relation to Diabetes Risk. Am J Epidemiol. 2017 Sep 15; 186(6):736-744. PMID: 28520887.
    Citations:    Fields:    Translation:Humans
  34. Stein MB, Ware EB, Mitchell C, Chen CY, Borja S, Cai T, Dempsey CL, Fullerton CS, Gelernter J, Heeringa SG, Jain S, Kessler RC, Naifeh JA, Nock MK, Ripke S, Sun X, Beckham JC, Kimbrel NA, Ursano RJ, Smoller JW. Genomewide association studies of suicide attempts in US soldiers. Am J Med Genet B Neuropsychiatr Genet. 2017 Dec; 174(8):786-797. PMID: 28902444.
    Citations: 2     Fields:    Translation:Humans
  35. Can A, Castro VM, Ozdemir YH, Dagen S, Yu S, Dligach D, Finan S, Gainer V, Shadick NA, Murphy S, Cai T, Savova G, Dammers R, Weiss ST, Du R. Association of intracranial aneurysm rupture with smoking duration, intensity, and cessation. Neurology. 2017 Sep 26; 89(13):1408-1415. PMID: 28855408.
    Citations: 5     Fields:    Translation:Humans
  36. Can A, Castro VM, Ozdemir YH, Dagen S, Dligach D, Finan S, Yu S, Gainer V, Shadick NA, Savova G, Murphy S, Cai T, Weiss ST, Du R. Alcohol Consumption and Aneurysmal Subarachnoid Hemorrhage. Transl Stroke Res. 2018 02; 9(1):13-19. PMID: 28752411.
    Citations: 2     Fields:    Translation:Humans
  37. Zheng Y, Brown M, Lok A, Cai T. IMPROVING EFFICIENCY IN BIOMARKER INCREMENTAL VALUE EVALUATION UNDER TWO-PHASE DESIGNS. Ann Appl Stat. 2017 Jun; 11(2):638-654. PMID: 28943991.
    Citations:    
  38. Naxerova K, Reiter JG, Brachtel E, Lennerz JK, van de Wetering M, Rowan A, Cai T, Clevers H, Swanton C, Nowak MA, Elledge SJ, Jain RK. Origins of lymphatic and distant metastases in human colorectal cancer. Science. 2017 Jul 07; 357(6346):55-60. PMID: 28684519.
    Citations: 24     Fields:    Translation:Humans
  39. Geva A, Gronsbell JL, Cai T, Cai T, Murphy SN, Lyons JC, Heinz MM, Natter MD, Patibandla N, Bickel J, Mullen MP, Mandl KD. A Computable Phenotype Improves Cohort Ascertainment in a Pediatric Pulmonary Hypertension Registry. J Pediatr. 2017 09; 188:224-231.e5. PMID: 28625502.
    Citations:    
  40. Ong MS, Mullen MP, Austin ED, Szolovits P, Natter MD, Geva A, Cai T, Kong SW, Mandl KD. Learning a Comorbidity-Driven Taxonomy of Pediatric Pulmonary Hypertension. Circ Res. 2017 Aug 04; 121(4):341-353. PMID: 28611076.
    Citations: 1     Fields:    Translation:Humans
  41. Agniel D, Cai T. Analysis of multiple diverse phenotypes via semiparametric canonical correlation analysis. Biometrics. 2017 12; 73(4):1254-1265. PMID: 28407213.
    Citations:    Fields:    Translation:Humans
  42. Xie W, Agniel D, Shevchenko A, Malov SV, Svitin A, Cherkasov N, Baum MK, Campa A, Gaseitsiwe S, Bussmann H, Makhema J, Marlink R, Novitsky V, Lee TH, Cai T, O'Brien SJ, Essex M. Genome-Wide Analyses Reveal Gene Influence on HIV Disease Progression and HIV-1C Acquisition in Southern Africa. AIDS Res Hum Retroviruses. 2017 06; 33(6):597-609. PMID: 28132517.
    Citations: 1     Fields:    Translation:HumansCells
  43. Yu S, Chakrabortty A, Liao KP, Cai T, Ananthakrishnan AN, Gainer VS, Churchill SE, Szolovits P, Murphy SN, Kohane IS, Cai T. Surrogate-assisted feature extraction for high-throughput phenotyping. J Am Med Inform Assoc. 2017 Apr 01; 24(e1):e143-e149. PMID: 27632993.
    Citations: 1     Fields:    Translation:Humans
  44. Liao KP, Sparks JA, Hejblum BP, Kuo IH, Cui J, Lahey LJ, Cagan A, Gainer VS, Liu W, Cai TT, Sokolove J, Cai T. Phenome-Wide Association Study of Autoantibodies to Citrullinated and Noncitrullinated Epitopes in Rheumatoid Arthritis. Arthritis Rheumatol. 2017 04; 69(4):742-749. PMID: 27792870.
    Citations: 5     Fields:    Translation:Humans
  45. Koch M, Furtado JD, Jiang GZ, Gray BE, Cai T, Sacks F, Tjønneland A, Overvad K, Jensen MK. Associations of anthropometry and lifestyle factors with HDL subspecies according to apolipoprotein C-III. J Lipid Res. 2017 06; 58(6):1196-1203. PMID: 28365588.
    Citations:    Fields:    Translation:Humans
  46. Zheng Y, Cai T. Augmented estimation for t-year survival with censored regression models. Biometrics. 2017 12; 73(4):1169-1178. PMID: 28294286.
    Citations:    Fields:    Translation:Humans
  47. Dai W, Yang M, Wang C, Cai T. Sequence robust association test for familial data. Biometrics. 2017 09; 73(3):876-884. PMID: 28273695.
    Citations:    Fields:    Translation:Humans
  48. Liu D, Cai T, Lok A, Zheng Y. Nonparametric Maximum Likelihood Estimators of Time-Dependent Accuracy Measures for Survival Outcome Under Two-Stage Sampling Designs. J Am Stat Assoc. 2018; 113(522):882-892. PMID: 30555194.
    Citations:    
  49. Chen S, Tian L, Cai T, Yu M. A general statistical framework for subgroup identification and comparative treatment scoring. Biometrics. 2017 12; 73(4):1199-1209. PMID: 28211943.
    Citations: 1     Fields:    Translation:Humans
  50. Parast L, Cai T, Tian L. Evaluating surrogate marker information using censored data. Stat Med. 2017 05 20; 36(11):1767-1782. PMID: 28088843.
    Citations:    Fields:    Translation:Humans
  51. Yong FH, Tian L, Yu S, Cai T, Wei LJ. Optimal stratification in outcome prediction using baseline information. Biometrika. 2016 12; 103(4):817-828. PMID: 29422691.
    Citations:    Fields:    
  52. Castro VM, Dligach D, Finan S, Yu S, Can A, Abd-El-Barr M, Gainer V, Shadick NA, Murphy S, Cai T, Savova G, Weiss ST, Du R. Large-scale identification of patients with cerebral aneurysms using natural language processing. Neurology. 2017 Jan 10; 88(2):164-168. PMID: 27927935.
    Citations: 12     Fields:    Translation:Humans
  53. Cai T, Cai TT, Zhang A. Structured Matrix Completion with Applications to Genomic Data Integration. J Am Stat Assoc. 2016; 111(514):621-633. PMID: 28042188.
    Citations:    
  54. He Q, Cai T, Liu Y, Zhao N, Harmon QE, Almli LM, Binder EB, Engel SM, Ressler KJ, Conneely KN, Lin X, Wu MC. Prioritizing individual genetic variants after kernel machine testing using variable selection. Genet Epidemiol. 2016 Dec; 40(8):722-731. PMID: 27488097.
    Citations: 1     Fields:    Translation:Humans
  55. Maziarz M, Heagerty P, Cai T, Zheng Y. On longitudinal prediction with time-to-event outcome: Comparison of modeling options. Biometrics. 2017 03; 73(1):83-93. PMID: 27438160.
    Citations: 1     Fields:    Translation:Humans
  56. Stein MB, Chen CY, Ursano RJ, Cai T, Gelernter J, Heeringa SG, Jain S, Jensen KP, Maihofer AX, Mitchell C, Nievergelt CM, Nock MK, Neale BM, Polimanti R, Ripke S, Sun X, Thomas ML, Wang Q, Ware EB, Borja S, Kessler RC, Smoller JW. Genome-wide Association Studies of Posttraumatic Stress Disorder in 2 Cohorts of US Army Soldiers. JAMA Psychiatry. 2016 07 01; 73(7):695-704. PMID: 27167565.
    Citations: 20     Fields:    Translation:HumansCells
  57. Kumamaru KK, Kumamaru H, Bateman BT, Gronsbell J, Cai T, Liu J, Higgins LD, Aoki S, Ohtomo K, Rybicki FJ, Patorno E. Limited Hospital Variation in the Use and Yield of CT for Pulmonary Embolism in Patients Undergoing Total Hip or Total Knee Replacement Surgery. Radiology. 2016 Dec; 281(3):826-834. PMID: 27228331.
    Citations: 2     Fields:    Translation:Humans
  58. Neykov M, Liu JS, Cai T. L1-Regularized Least Squares for Support Recovery of High Dimensional Single Index Models with Gaussian Designs. J Mach Learn Res. 2016 May; 17(1):2976-3012. PMID: 28503101.
    Citations:    
  59. Sinnott JA, Cai T. Inference for survival prediction under the regularized Cox model. Biostatistics. 2016 10; 17(4):692-707. PMID: 27107008.
    Citations: 2     Fields:    Translation:Humans
  60. Ananthakrishnan AN, Cagan A, Cai T, Gainer VS, Shaw SY, Savova G, Churchill S, Karlson EW, Kohane I, Liao KP, Murphy SN. Comparative Effectiveness of Infliximab and Adalimumab in Crohn's Disease and Ulcerative Colitis. Inflamm Bowel Dis. 2016 Apr; 22(4):880-5. PMID: 26933751.
    Citations: 5     Fields:    Translation:Humans
  61. Payne R, Yang M, Zheng Y, Jensen MK, Cai T. Robust risk prediction with biomarkers under two-phase stratified cohort design. Biometrics. 2016 12; 72(4):1037-1045. PMID: 27037494.
    Citations:    Fields:    Translation:Humans
  62. Shen Y, Cai T. Identifying predictive markers for personalized treatment selection. Biometrics. 2016 12; 72(4):1017-1025. PMID: 26999054.
    Citations: 2     Fields:    Translation:Humans
  63. Agniel D, Liao KP, Cai T. Estimation and testing for multiple regulation of multivariate mixed outcomes. Biometrics. 2016 12; 72(4):1194-1205. PMID: 26910481.
    Citations: 1     Fields:    Translation:Humans
  64. Ananthakrishnan AN, Cagan A, Cai T, Gainer VS, Shaw SY, Churchill S, Karlson EW, Murphy SN, Liao KP, Kohane I. Statin Use Is Associated With Reduced Risk of Colorectal Cancer in Patients With Inflammatory Bowel Diseases. Clin Gastroenterol Hepatol. 2016 07; 14(7):973-9. PMID: 26905907.
    Citations: 5     Fields:    Translation:Humans
  65. Ananthakrishnan AN, Cagan A, Cai T, Gainer VS, Shaw SY, Savova G, Churchill S, Karlson EW, Murphy SN, Liao KP, Kohane I. Identification of Nonresponse to Treatment Using Narrative Data in an Electronic Health Record Inflammatory Bowel Disease Cohort. Inflamm Bowel Dis. 2016 Jan; 22(1):151-8. PMID: 26332313.
    Citations: 4     Fields:    Translation:Humans
  66. Payne R, Neykov M, Jensen MK, Cai T. Kernel machine testing for risk prediction with stratified case cohort studies. Biometrics. 2016 06; 72(2):372-81. PMID: 26692376.
    Citations:    Fields:    Translation:Humans
  67. Li J, Zhao L, Tian L, Cai T, Claggett B, Callegaro A, Dizier B, Spiessens B, Ulloa-Montoya F, Wei LJ. A predictive enrichment procedure to identify potential responders to a new therapy for randomized, comparative controlled clinical studies. Biometrics. 2016 09; 72(3):877-87. PMID: 26689167.
    Citations: 6     Fields:    Translation:Humans
  68. Zhong QY, Gelaye B, Miller M, Fricchione GL, Cai T, Johnson PA, Henderson DC, Williams MA. Suicidal behavior-related hospitalizations among pregnant women in the USA, 2006-2012. Arch Womens Ment Health. 2016 06; 19(3):463-72. PMID: 26680447.
    Citations: 4     Fields:    Translation:Humans
  69. Huang YT, Cai T. Mediation analysis for survival data using semiparametric probit models. Biometrics. 2016 06; 72(2):563-74. PMID: 26618735.
    Citations: 2     Fields:    Translation:Humans
  70. Ananthakrishnan AN, Cagan A, Cai T, Gainer VS, Shaw SY, Churchill S, Karlson EW, Murphy SN, Kohane I, Liao KP, Xavier RJ. Common Genetic Variants Influence Circulating Vitamin D Levels in Inflammatory Bowel Diseases. Inflamm Bowel Dis. 2015 Nov; 21(11):2507-14. PMID: 26241000.
    Citations: 6     Fields:    Translation:Humans
  71. Castro V, Shen Y, Yu S, Finan S, Pau CT, Gainer V, Keefe CC, Savova G, Murphy SN, Cai T, Welt CK. Identification of subjects with polycystic ovary syndrome using electronic health records. Reprod Biol Endocrinol. 2015 Oct 29; 13:116. PMID: 26510685; PMCID: PMC4625743.
    Citations: 5     Fields:    Translation:Humans
  72. Liao KP, Ananthakrishnan AN, Kumar V, Xia Z, Cagan A, Gainer VS, Goryachev S, Chen P, Savova GK, Agniel D, Churchill S, Lee J, Murphy SN, Plenge RM, Szolovits P, Kohane I, Shaw SY, Karlson EW, Cai T. Methods to Develop an Electronic Medical Record Phenotype Algorithm to Compare the Risk of Coronary Artery Disease across 3 Chronic Disease Cohorts. PLoS One. 2015; 10(8):e0136651. PMID: 26301417.
    Citations: 10     Fields:    Translation:Humans
  73. Uno H, Wittes J, Fu H, Solomon SD, Claggett B, Tian L, Cai T, Pfeffer MA, Evans SR, Wei LJ. Alternatives to Hazard Ratios for Comparing the Efficacy or Safety of Therapies in Noninferiority Studies. Ann Intern Med. 2015 Jul 21; 163(2):127-34. PMID: 26054047; PMCID: PMC4510023.
    Citations: 13     Fields:    Translation:Humans
  74. Zhou QM, Zheng Y, Chibnik LB, Karlson EW, Cai T. Assessing incremental value of biomarkers with multi-phase nested case-control studies. Biometrics. 2015 Dec; 71(4):1139-49. PMID: 26195245.
    Citations:    Fields:    Translation:Humans
  75. Shen Y, Cai T, Chen Y, Yang Y, Chen J. Retrospective likelihood-based methods for analyzing case-cohort genetic association studies. Biometrics. 2015 Dec; 71(4):960-8. PMID: 26177343; PMCID: PMC4751872.
    Citations: 1     Fields:    Translation:Humans
  76. Yu S, Liao KP, Shaw SY, Gainer VS, Churchill SE, Szolovits P, Murphy SN, Kohane IS, Cai T. Toward high-throughput phenotyping: unbiased automated feature extraction and selection from knowledge sources. J Am Med Inform Assoc. 2015 Sep; 22(5):993-1000. PMID: 25929596; PMCID: PMC4986664.
    Citations: 27     Fields:    Translation:Humans
  77. Liao KP, Cai T, Savova GK, Murphy SN, Karlson EW, Ananthakrishnan AN, Gainer VS, Shaw SY, Xia Z, Szolovits P, Churchill S, Kohane I. Development of phenotype algorithms using electronic medical records and incorporating natural language processing. BMJ. 2015 Apr 24; 350:h1885. PMID: 25911572; PMCID: PMC4707569.
    Citations: 23     Fields:    Translation:Humans
  78. Minnier J, Yuan M, Liu JS, Cai T. Risk Classification with an Adaptive Naive Bayes Kernel Machine Model. J Am Stat Assoc. 2015 Apr 22; 110(509):393-404. PMID: 26236061.
    Citations: 2     
  79. Xia Y, Cai T, Cai TT. Testing Differential Networks with Applications to Detecting Gene-by-Gene Interactions. Biometrika. 2015 Jun; 102(2):247-266. PMID: 28502988.
    Citations: 2     Fields:    
  80. Kessler RC, Warner CH, Ivany C, Petukhova MV, Rose S, Bromet EJ, Brown M, Cai T, Colpe LJ, Cox KL, Fullerton CS, Gilman SE, Gruber MJ, Heeringa SG, Lewandowski-Romps L, Li J, Millikan-Bell AM, Naifeh JA, Nock MK, Rosellini AJ, Sampson NA, Schoenbaum M, Stein MB, Wessely S, Zaslavsky AM, Ursano RJ. Predicting suicides after psychiatric hospitalization in US Army soldiers: the Army Study To Assess Risk and rEsilience in Servicemembers (Army STARRS). JAMA Psychiatry. 2015 Jan; 72(1):49-57. PMID: 25390793; PMCID: PMC4286426.
    Citations: 37     Fields:    Translation:Humans
  81. Castro VM, Minnier J, Murphy SN, Kohane I, Churchill SE, Gainer V, Cai T, Hoffnagle AG, Dai Y, Block S, Weill SR, Nadal-Vicens M, Pollastri AR, Rosenquist JN, Goryachev S, Ongur D, Sklar P, Perlis RH, Smoller JW. Validation of electronic health record phenotyping of bipolar disorder cases and controls. Am J Psychiatry. 2015 Apr; 172(4):363-72. PMID: 25827034.
    Citations: 17     Fields:    Translation:Humans
  82. Ananthakrishnan AN, Cheng A, Cagan A, Cai T, Gainer VS, Shaw SY, Churchill S, Karlson EW, Murphy SN, Kohane I, Liao KP. Mode of childbirth and long-term outcomes in women with inflammatory bowel diseases. Dig Dis Sci. 2015 Feb; 60(2):471-7. PMID: 25213079; PMCID: PMC4304947.
    Citations: 2     Fields:    Translation:Humans
  83. Shen Y, Liao KP, Cai T. Sparse kernel machine regression for ordinal outcomes. Biometrics. 2015 Mar; 71(1):63-70. PMID: 25196727; PMCID: PMC4609171.
    Citations: 1     Fields:    Translation:Humans
  84. Yu S, Kumamaru KK, George E, Dunne RM, Bedayat A, Neykov M, Hunsaker AR, Dill KE, Cai T, Rybicki FJ. Classification of CT pulmonary angiography reports by presence, chronicity, and location of pulmonary embolism with natural language processing. J Biomed Inform. 2014 Dec; 52:386-93. PMID: 25117751; PMCID: PMC4261018.
    Citations: 4     Fields:    Translation:Humans
  85. Sinnott JA, Dai W, Liao KP, Shaw SY, Ananthakrishnan AN, Gainer VS, Karlson EW, Churchill S, Szolovits P, Murphy S, Kohane I, Plenge R, Cai T. Improving the power of genetic association tests with imperfect phenotype derived from electronic medical records. Hum Genet. 2014 Nov; 133(11):1369-82. PMID: 25062868; PMCID: PMC4185241.
    Citations: 7     Fields:    Translation:Humans
  86. Ananthakrishnan AN, Cagan A, Cai T, Gainer VS, Shaw SY, Churchill S, Karlson EW, Murphy SN, Kohane I, Liao KP. Colonoscopy is associated with a reduced risk for colon cancer and mortality in patients with inflammatory bowel diseases. Clin Gastroenterol Hepatol. 2015 Feb; 13(2):322-329.e1. PMID: 25041865.
    Citations: 15     Fields:    Translation:Humans
  87. Ong MS, Kohane IS, Cai T, Gorman MP, Mandl KD. Population-level evidence for an autoimmune etiology of epilepsy. JAMA Neurol. 2014 May; 71(5):569-74. PMID: 24687183; PMCID: PMC4324719.
    Citations: 23     Fields:    Translation:HumansPHPublic Health
  88. Matsouaka RA, Li J, Cai T. Evaluating marker-guided treatment selection strategies. Biometrics. 2014 Sep; 70(3):489-499. PMID: 24779731; PMCID: PMC4213325.
    Citations: 7     Fields:    Translation:Humans
  89. Ananthakrishnan AN, Cagan A, Gainer VS, Cheng SC, Cai T, Scoville E, Konijeti GG, Szolovits P, Shaw SY, Churchill S, Karlson EW, Murphy SN, Kohane I, Liao KP. Thromboprophylaxis is associated with reduced post-hospitalization venous thromboembolic events in patients with inflammatory bowel diseases. Clin Gastroenterol Hepatol. 2014 Nov; 12(11):1905-10. PMID: 24632349.
    Citations: 6     Fields:    Translation:Humans
  90. Ananthakrishnan AN, Cagan A, Gainer VS, Cheng SC, Cai T, Szolovits P, Shaw SY, Churchill S, Karlson EW, Murphy SN, Kohane I, Liao KP. Mortality and extraintestinal cancers in patients with primary sclerosing cholangitis and inflammatory bowel disease. J Crohns Colitis. 2014 Sep; 8(9):956-63. PMID: 24559536; PMCID: PMC4136996.
    Citations: 11     Fields:    Translation:Humans
  91. van Loo HM, Cai T, Gruber MJ, Li J, de Jonge P, Petukhova M, Rose S, Sampson NA, Schoevers RA, Wardenaar KJ, Wilcox MA, Al-Hamzawi AO, Andrade LH, Bromet EJ, Bunting B, Fayyad J, Florescu SE, Gureje O, Hu C, Huang Y, Levinson D, Medina-Mora ME, Nakane Y, Posada-Villa J, Scott KM, Xavier M, Zarkov Z, Kessler RC. Major depressive disorder subtypes to predict long-term course. Depress Anxiety. 2014 Sep; 31(9):765-77. PMID: 24425049.
    Citations: 7     Fields:    Translation:Humans
  92. Ananthakrishnan AN, Cheng SC, Cai T, Cagan A, Gainer VS, Szolovits P, Shaw SY, Churchill S, Karlson EW, Murphy SN, Kohane I, Liao KP. Serum inflammatory markers and risk of colorectal cancer in patients with inflammatory bowel diseases. Clin Gastroenterol Hepatol. 2014 Aug; 12(8):1342-8.e1. PMID: 24407106.
    Citations: 11     Fields:    Translation:Humans
  93. Parast L, Tian L, Cai T. Landmark Estimation of Survival and Treatment Effect in a Randomized Clinical Trial. J Am Stat Assoc. 2014 Jan 01; 109(505):384-394. PMID: 24659838.
    Citations: 4     
  94. Lai PS, Hang JQ, Zhang FY, Lin X, Zheng BY, Dai HL, Su L, Cai T, Christiani DC. Gender differences in the effect of occupational endotoxin exposure on impaired lung function and death: the Shanghai Textile Worker Study. Occup Environ Med. 2014 Feb; 71(2):118-125. PMID: 24297825; PMCID: PMC4033669.
    Citations: 3     Fields:    Translation:HumansPHPublic Health
  95. Liao KP, Cai T, Gainer VS, Cagan A, Murphy SN, Liu C, Churchill S, Shaw SY, Kohane I, Solomon DH, Plenge RM, Karlson EW. Lipid and lipoprotein levels and trend in rheumatoid arthritis compared to the general population. Arthritis Care Res (Hoboken). 2013 Dec; 65(12):2046-50. PMID: 23925980; PMCID: PMC4060244.
    Citations: 13     Fields:    Translation:Humans
  96. Xia Z, Secor E, Chibnik LB, Bove RM, Cheng S, Chitnis T, Cagan A, Gainer VS, Chen PJ, Liao KP, Shaw SY, Ananthakrishnan AN, Szolovits P, Weiner HL, Karlson EW, Murphy SN, Savova GK, Cai T, Churchill SE, Plenge RM, Kohane IS, De Jager PL. Modeling disease severity in multiple sclerosis using electronic health records. PLoS One. 2013; 8(11):e78927. PMID: 24244385; PMCID: PMC3823928.
    Citations: 19     Fields:    Translation:HumansCTClinical Trials
  97. Sinnott JA, Cai T. Omnibus risk assessment via accelerated failure time kernel machine modeling. Biometrics. 2013 Dec; 69(4):861-73. PMID: 24328713; PMCID: PMC3869038.
    Citations: 3     Fields:    Translation:Humans
  98. Ananthakrishnan AN, Cheng SC, Cai T, Cagan A, Gainer VS, Szolovits P, Shaw SY, Churchill S, Karlson EW, Murphy SN, Kohane I, Liao KP. Association between reduced plasma 25-hydroxy vitamin D and increased risk of cancer in patients with inflammatory bowel diseases. Clin Gastroenterol Hepatol. 2014 May; 12(5):821-7. PMID: 24161349.
    Citations: 26     Fields:    Translation:Humans
  99. Zhou QM, Zheng Y, Cai T. Assessment of biomarkers for risk prediction with nested case-control studies. Clin Trials. 2013 Oct; 10(5):677-9. PMID: 24013405; PMCID: PMC3800233.
    Citations:    Fields:    Translation:Humans
  100. Cai T, Betensky R. Reply to Sabanés Bové and Held's "comment on Cai and Betensky (2003), on the poisson approximation for hazard regression". Biometrics. 2013 Sep; 69(3):796. PMID: 24073867; PMCID: PMC4609170.
    Citations:    Fields:    Translation:Humans
  101. Ananthakrishnan AN, Cagan A, Gainer VS, Cai T, Cheng SC, Savova G, Chen P, Szolovits P, Xia Z, De Jager PL, Shaw SY, Churchill S, Karlson EW, Kohane I, Plenge RM, Murphy SN, Liao KP. Normalization of plasma 25-hydroxy vitamin D is associated with reduced risk of surgery in Crohn's disease. Inflamm Bowel Dis. 2013 Aug; 19(9):1921-7. PMID: 23751398.
    Citations: 50     Fields:    Translation:Humans
  102. Altschuler GM, Hofmann O, Kalatskaya I, Payne R, Ho Sui SJ, Saxena U, Krivtsov AV, Armstrong SA, Cai T, Stein L, Hide WA. Pathprinting: An integrative approach to understand the functional basis of disease. Genome Med. 2013; 5(7):68. PMID: 23890051; PMCID: PMC3971351.
    Citations: 4     Fields:    
  103. Zheng Y, Cai T, Pepe MS. Adopting nested case-control quota sampling designs for the evaluation of risk markers. Lifetime Data Anal. 2013 Oct; 19(4):568-88. PMID: 23807695; PMCID: PMC3903399.
    Citations: 1     Fields:    Translation:Humans
  104. Ananthakrishnan AN, Cai T, Savova G, Cheng SC, Chen P, Perez RG, Gainer VS, Murphy SN, Szolovits P, Xia Z, Shaw S, Churchill S, Karlson EW, Kohane I, Plenge RM, Liao KP. Improving case definition of Crohn's disease and ulcerative colitis in electronic medical records using natural language processing: a novel informatics approach. Inflamm Bowel Dis. 2013 Jun; 19(7):1411-20. PMID: 23567779.
    Citations: 40     Fields:    Translation:Humans
  105. Liao KP, Diogo D, Cui J, Cai T, Okada Y, Gainer VS, Murphy SN, Gupta N, Mirel D, Ananthakrishnan AN, Szolovits P, Shaw SY, Raychaudhuri S, Churchill S, Kohane I, Karlson EW, Plenge RM. Association between low density lipoprotein and rheumatoid arthritis genetic factors with low density lipoprotein levels in rheumatoid arthritis and non-rheumatoid arthritis controls. Ann Rheum Dis. 2014 Jun; 73(6):1170-5. PMID: 23716066; PMCID: PMC3815491.
    Citations: 8     Fields:    Translation:Humans
  106. Parast L, Cai T. Landmark risk prediction of residual life for breast cancer survival. Stat Med. 2013 Sep 10; 32(20):3459-71. PMID: 23494768.
    Citations: 1     Fields:    Translation:Humans
  107. Liao KP, Kurreeman F, Li G, Duclos G, Murphy S, Guzman R, Cai T, Gupta N, Gainer V, Schur P, Cui J, Denny JC, Szolovits P, Churchill S, Kohane I, Karlson EW, Plenge RM. Associations of autoantibodies, autoimmune risk alleles, and clinical diagnoses from the electronic medical records in rheumatoid arthritis cases and non-rheumatoid arthritis controls. Arthritis Rheum. 2013 Mar; 65(3):571-81. PMID: 23233247; PMCID: PMC3582761.
    Citations: 31     Fields:    Translation:Humans
  108. Ananthakrishnan AN, Gainer VS, Cai T, Perez RG, Cheng SC, Savova G, Chen P, Szolovits P, Xia Z, De Jager PL, Shaw S, Churchill S, Karlson EW, Kohane I, Perlis RH, Plenge RM, Murphy SN, Liao KP. Similar risk of depression and anxiety following surgery or hospitalization for Crohn's disease and ulcerative colitis. Am J Gastroenterol. 2013 Apr; 108(4):594-601. PMID: 23337479; PMCID: PMC3627544.
    Citations: 16     Fields:    Translation:Humans
  109. Ananthakrishnan AN, Gainer VS, Perez RG, Cai T, Cheng SC, Savova G, Chen P, Szolovits P, Xia Z, De Jager PL, Shaw SY, Churchill S, Karlson EW, Kohane I, Perlis RH, Plenge RM, Murphy SN, Liao KP. Psychiatric co-morbidity is associated with increased risk of surgery in Crohn's disease. Aliment Pharmacol Ther. 2013 Feb; 37(4):445-54. PMID: 23289600; PMCID: PMC3552092.
    Citations: 24     Fields:    Translation:Humans
  110. Cai T, Zheng Y. Resampling Procedures for Making Inference under Nested Case-control Studies. J Am Stat Assoc. 2013 Jan 01; 108(504):1532-1544. PMID: 24436503.
    Citations: 3     
  111. Zhao L, Tian L, Cai T, Claggett B, Wei LJ. EFFECTIVELY SELECTING A TARGET POPULATION FOR A FUTURE COMPARATIVE STUDY. J Am Stat Assoc. 2013 Jan 01; 108(502):527-539. PMID: 24058223.
    Citations: 24     
  112. Zhou QM, Zheng Y, Cai T. Subgroup specific incremental value of new markers for risk prediction. Lifetime Data Anal. 2013 Apr; 19(2):142-69. PMID: 23263882; PMCID: PMC3633735.
    Citations: 1     Fields:    Translation:Humans
  113. Zheng Y, Parast L, Cai T, Brown M. Evaluating incremental values from new predictors with net reclassification improvement in survival analysis. Lifetime Data Anal. 2013 Jul; 19(3):350-70. PMID: 23254468.
    Citations: 1     Fields:    Translation:Humans
  114. Liu D, Cai T, Zheng Y. Evaluating the predictive value of biomarkers with stratified case-cohort design. Biometrics. 2012 Dec; 68(4):1219-27. PMID: 23173848; PMCID: PMC3718317.
    Citations: 5     Fields:    Translation:Humans
  115. Uno H, Tian L, Cai T, Kohane IS, Wei LJ. A unified inference procedure for a class of measures to assess improvement in risk prediction systems with survival data. Stat Med. 2013 Jun 30; 32(14):2430-42. PMID: 23037800.
    Citations: 43     Fields:    Translation:Humans
  116. Parast L, Cheng SC, Cai T. Landmark Prediction of Long Term Survival Incorporating Short Term Event Time Information. J Am Stat Assoc. 2012; 107(500):1492-1501. PMID: 23293405.
    Citations: 5     
  117. Cai T, Lin X, Carroll RJ. Identifying genetic marker sets associated with phenotypes via an efficient adaptive score test. Biostatistics. 2012 Sep; 13(4):776-90. PMID: 22734045; PMCID: PMC3440238.
    Citations: 11     Fields:    Translation:Humans
  118. Lu MT, Demehri S, Cai T, Parast L, Hunsaker AR, Goldhaber SZ, Rybicki FJ. Axial and reformatted four-chamber right ventricle-to-left ventricle diameter ratios on pulmonary CT angiography as predictors of death after acute pulmonary embolism. AJR Am J Roentgenol. 2012 Jun; 198(6):1353-60. PMID: 22623548.
    Citations: 10     Fields:    Translation:Humans
  119. León LF, Cai T. Model Checking Techniques for Assessing Functional Form Specifications in Censored Linear Regression Models. Stat Sin. 2012 Apr 01; 22(2):509-530. PMID: 23825917.
    Citations:    
  120. Carroll RJ, Thompson WK, Eyler AE, Mandelin AM, Cai T, Zink RM, Pacheco JA, Boomershine CS, Lasko TA, Xu H, Karlson EW, Perez RG, Gainer VS, Murphy SN, Ruderman EM, Pope RM, Plenge RM, Kho AN, Liao KP, Denny JC. Portability of an algorithm to identify rheumatoid arthritis in electronic health records. J Am Med Inform Assoc. 2012 Jun; 19(e1):e162-9. PMID: 22374935; PMCID: PMC3392871.
    Citations: 81     Fields:    Translation:Humans
  121. Ananthakrishnan AN, Guzman-Perez R, Gainer V, Cai T, Churchill S, Kohane I, Plenge RM, Murphy S. Predictors of severe outcomes associated with Clostridium difficile infection in patients with inflammatory bowel disease. Aliment Pharmacol Ther. 2012 Apr; 35(7):789-95. PMID: 22360370; PMCID: PMC3716251.
    Citations: 20     Fields:    Translation:HumansCells
  122. Tian L, Cai T, Zhao L, Wei LJ. On the covariate-adjusted estimation for an overall treatment difference with data from a randomized comparative clinical trial. Biostatistics. 2012 Apr; 13(2):256-73. PMID: 22294672; PMCID: PMC3297822.
    Citations: 9     Fields:    Translation:Humans
  123. Qi L, Parast L, Cai T, Powers C, Gervino EV, Hauser TH, Hu FB, Doria A. Genetic susceptibility to coronary heart disease in type 2 diabetes: 3 independent studies. J Am Coll Cardiol. 2011 Dec 13; 58(25):2675-82. PMID: 22152955; PMCID: PMC3240896.
    Citations: 27     Fields:    Translation:Humans
  124. Zheng Y, Cai T, Jin Y, Feng Z. Evaluating prognostic accuracy of biomarkers under competing risk. Biometrics. 2012 Jun; 68(2):388-96. PMID: 22150576; PMCID: PMC3694786.
    Citations: 5     Fields:    Translation:Humans
  125. Cai T, Zheng Y. Evaluating prognostic accuracy of biomarkers in nested case-control studies. Biostatistics. 2012 Jan; 13(1):89-100. PMID: 21856652; PMCID: PMC3276269.
    Citations: 9     Fields:    Translation:Humans
  126. Lin X, Cai T, Wu MC, Zhou Q, Liu G, Christiani DC, Lin X. Kernel machine SNP-set analysis for censored survival outcomes in genome-wide association studies. Genet Epidemiol. 2011 Nov; 35(7):620-31. PMID: 21818772; PMCID: PMC3373190.
    Citations: 24     Fields:    Translation:Humans
  127. Wu MC, Lee S, Cai T, Li Y, Boehnke M, Lin X. Rare-variant association testing for sequencing data with the sequence kernel association test. Am J Hum Genet. 2011 Jul 15; 89(1):82-93. PMID: 21737059; PMCID: PMC3135811.
    Citations: 724     Fields:    Translation:Humans
  128. Perlis RH, Iosifescu DV, Castro VM, Murphy SN, Gainer VS, Minnier J, Cai T, Goryachev S, Zeng Q, Gallagher PJ, Fava M, Weilburg JB, Churchill SE, Kohane IS, Smoller JW. Using electronic medical records to enable large-scale studies in psychiatry: treatment resistant depression as a model. Psychol Med. 2012 Jan; 42(1):41-50. PMID: 21682950; PMCID: PMC3837420.
    Citations: 47     Fields:    Translation:Humans
  129. Uno H, Cai T, Tian L, Wei LJ. Graphical procedures for evaluating overall and subject-specific incremental values from new predictors with censored event time data. Biometrics. 2011 Dec; 67(4):1389-96. PMID: 21504421.
    Citations: 2     Fields:    Translation:Humans
  130. Cai T, Tian L, Lloyd-Jones DM. Comparing costs associated with risk stratification rules for t-year survival. Biostatistics. 2011 Oct; 12(4):597-609. PMID: 21415016; PMCID: PMC3169667.
    Citations: 1     Fields:    Translation:Humans
  131. Parast L, Cheng SC, Cai T. Incorporating short-term outcome information to predict long-term survival with discrete markers. Biom J. 2011 Mar; 53(2):294-307. PMID: 21337601.
    Citations: 4     Fields:    Translation:HumansPHPublic Health
  132. Cai T, Tonini G, Lin X. Kernel machine approach to testing the significance of multiple genetic markers for risk prediction. Biometrics. 2011 Sep; 67(3):975-86. PMID: 21281275; PMCID: PMC3165098.
    Citations: 21     Fields:    Translation:Humans
  133. Uno H, Cai T, Pencina MJ, D'Agostino RB, Wei LJ. On the C-statistics for evaluating overall adequacy of risk prediction procedures with censored survival data. Stat Med. 2011 May 10; 30(10):1105-17. PMID: 21484848; PMCID: PMC3079915.
    Citations: 127     Fields:    Translation:Humans
  134. Kurreeman F, Liao K, Chibnik L, Hickey B, Stahl E, Gainer V, Li G, Bry L, Mahan S, Ardlie K, Thomson B, Szolovits P, Churchill S, Murphy SN, Cai T, Raychaudhuri S, Kohane I, Karlson E, Plenge RM. Genetic basis of autoantibody positive and negative rheumatoid arthritis risk in a multi-ethnic cohort derived from electronic health records. Am J Hum Genet. 2011 Jan 07; 88(1):57-69. PMID: 21211616; PMCID: PMC3014362.
    Citations: 48     Fields:    Translation:Humans
  135. Minnier J, Tian L, Cai T. A Perturbation Method for Inference on Regularized Regression Estimates. J Am Stat Assoc. 2011 Jan 01; 106(496):1371-1382. PMID: 22844171.
    Citations: 10     
  136. Cai T, Zheng Y. Non-parametric Evaluation of Biomarker Accuracy under Nested Case-control Studies. J Am Stat Assoc. 2011 Jan 01; 106(494):569-580. PMID: 22844169.
    Citations: 6     
  137. McDaniel S, Minnier J, Betensky RA, Mohapatra G, Shen Y, Gusella JF, Louis DN, Cai T. Assessing Population Level Genetic Instability via Moving Average. Stat Biosci. 2010 Dec; 2(2):120-136. PMID: 22866169.
    Citations:    
  138. Cai T, Tian L, Wong PH, Wei LJ. Analysis of randomized comparative clinical trial data for personalized treatment selections. Biostatistics. 2011 Apr; 12(2):270-82. PMID: 20876663; PMCID: PMC3062150.
    Citations: 32     Fields:    Translation:HumansCells
  139. Cai T, Parast L, Ryan L. Meta-analysis for rare events. Stat Med. 2010 Sep 10; 29(20):2078-89. PMID: 20623822; PMCID: PMC2932857.
    Citations: 13     Fields:    Translation:Humans
  140. Tian L, Wang R, Cai T, Wei LJ. The highest confidence density region and its usage for joint inferences about constrained parameters. Biometrics. 2011 Jun; 67(2):604-10. PMID: 20825392.
    Citations: 1     Fields:    
  141. Love TJ, Cai T, Karlson EW. Validation of psoriatic arthritis diagnoses in electronic medical records using natural language processing. Semin Arthritis Rheum. 2011 Apr; 40(5):413-20. PMID: 20701955; PMCID: PMC3691811.
    Citations: 11     Fields:    Translation:Humans
  142. Hunsaker AR, Oliva IB, Cai T, Trotman-Dickenson B, Gill RR, Hatabu H, Rybicki FJ. Contrast opacification using a reduced volume of iodinated contrast material and low peak kilovoltage in pulmonary CT angiography: Objective and subjective evaluation. AJR Am J Roentgenol. 2010 Aug; 195(2):W118-24. PMID: 20651170.
    Citations: 11     Fields:    Translation:Humans
  143. Liao KP, Cai T, Gainer V, Goryachev S, Zeng-treitler Q, Raychaudhuri S, Szolovits P, Churchill S, Murphy S, Kohane I, Karlson EW, Plenge RM. Electronic medical records for discovery research in rheumatoid arthritis. Arthritis Care Res (Hoboken). 2010 Aug; 62(8):1120-7. PMID: 20235204; PMCID: PMC3121049.
    Citations: 99     Fields:    Translation:Humans
  144. Cai T, Gerds TA, Zheng Y, Chen J. Robust prediction of t-year survival with data from multiple studies. Biometrics. 2011 Jun; 67(2):436-44. PMID: 20670303; PMCID: PMC2987565.
    Citations: 3     Fields:    Translation:Humans
  145. Gao X, Lai CQ, Scott T, Shen J, Cai T, Ordovas JM, Tucker KL. Urinary 8-hydroxy-2-deoxyguanosine and cognitive function in Puerto Rican adults. Am J Epidemiol. 2010 Aug 01; 172(3):271-8. PMID: 20621990; PMCID: PMC3026653.
    Citations: 3     Fields:    Translation:Humans
  146. Wu C, Sodickson A, Cai T, Levit NA, Steigner ML, Rybicki FJ, Ledbetter SM. Comparison of respiratory motion artifact from craniocaudal versus caudocranial scanning with 64-MDCT pulmonary angiography. AJR Am J Roentgenol. 2010 Jul; 195(1):155-9. PMID: 20566810.
    Citations:    Fields:    Translation:Humans
  147. Cai T, Tian L, Uno H, Solomon SD, Wei LJ. Calibrating parametric subject-specific risk estimation. Biometrika. 2010 Jun; 97(2):389-404. PMID: 23049123.
    Citations: 18     Fields:    
  148. Rybicki FJ, Mitsouras D, Owens CD, Whitmore A, Gerhard-Herman M, Wake N, Cai T, Zhou Q, Conte MS, Creager MA, Mulkern RV. Multi-contrast high spatial resolution black blood inner volume three-dimensional fast spin echo MR imaging in peripheral vein bypass grafts. Int J Cardiovasc Imaging. 2010 Aug; 26(6):683-91. PMID: 20333469; PMCID: PMC4431652.
    Citations: 5     Fields:    Translation:Humans
  149. Wang R, Tian L, Cai T, Wei LJ. NONPARAMETRIC INFERENCE PROCEDURE FOR PERCENTILES OF THE RANDOM EFFECTS DISTRIBUTION IN META-ANALYSIS. Ann Appl Stat. 2010; 4(1):520-532. PMID: 25678939.
    Citations: 2     
  150. Steigner ML, Mitsouras D, Whitmore AG, Otero HJ, Wang C, Buckley O, Levit NA, Hussain AZ, Cai T, Mather RT, Smedby O, DiCarli MF, Rybicki FJ. Iodinated contrast opacification gradients in normal coronary arteries imaged with prospectively ECG-gated single heart beat 320-detector row computed tomography. Circ Cardiovasc Imaging. 2010 Mar; 3(2):179-86. PMID: 20044512; PMCID: PMC3063948.
    Citations: 49     Fields:    Translation:Humans
  151. Wu CJ, Cai T, Rikova K, Merberg D, Kasif S, Steffen M. A predictive phosphorylation signature of lung cancer. PLoS One. 2009 Nov 25; 4(11):e7994. PMID: 19946374; PMCID: PMC2777383.
    Citations: 6     Fields:    Translation:HumansCells
  152. Cai T, Huang J, Tian L. Regularized estimation for the accelerated failure time model. Biometrics. 2009 Jun; 65(2):394-404. PMID: 18573133; PMCID: PMC3073158.
    Citations: 24     Fields:    
  153. Cornelis MC, Qi L, Zhang C, Kraft P, Manson J, Cai T, Hunter DJ, Hu FB. Joint effects of common genetic variants on the risk for type 2 diabetes in U.S. men and women of European ancestry. Ann Intern Med. 2009 Apr 21; 150(8):541-50. PMID: 19380854; PMCID: PMC3825275.
    Citations: 97     Fields:    Translation:Humans
  154. Zheng Y, Cai T, Stanford JL, Feng Z. Semiparametric models of time-dependent predictive values of prognostic biomarkers. Biometrics. 2010 Mar; 66(1):50-60. PMID: 19397579; PMCID: PMC2875380.
    Citations: 6     Fields:    Translation:Humans
  155. Ren N, Kaplan R, Hernandez M, Cheng K, Jin L, Taggart AK, Zhu AY, Gan X, Wright SD, Cai TQ. Phenolic acids suppress adipocyte lipolysis via activation of the nicotinic acid receptor GPR109A (HM74a/PUMA-G). J Lipid Res. 2009 May; 50(5):908-14. PMID: 19136666.
    Citations: 5     Fields:    Translation:HumansAnimalsCells
  156. Chien K, Cai T, Hsu H, Su T, Chang W, Chen M, Lee Y, Hu FB. A prediction model for type 2 diabetes risk among Chinese people. Diabetologia. 2009 Mar; 52(3):443-50. PMID: 19057891.
    Citations: 36     Fields:    Translation:Humans
  157. Tian L, Cai T, Pfeffer MA, Piankov N, Cremieux PY, Wei LJ. Exact and efficient inference procedure for meta-analysis and its application to the analysis of independent 2 x 2 tables with all available data but without artificial continuity correction. Biostatistics. 2009 Apr; 10(2):275-81. PMID: 18922759; PMCID: PMC2648899.
    Citations: 11     Fields:    Translation:Humans
  158. Gerds TA, Cai T, Schumacher M. The performance of risk prediction models. Biom J. 2008 Aug; 50(4):457-79. PMID: 18663757.
    Citations: 45     Fields:    Translation:Humans
  159. Steigner ML, Otero HJ, Cai T, Mitsouras D, Nallamshetty L, Whitmore AG, Ersoy H, Levit NA, Di Carli MF, Rybicki FJ. Narrowing the phase window width in prospectively ECG-gated single heart beat 320-detector row coronary CT angiography. Int J Cardiovasc Imaging. 2009 Jan; 25(1):85-90. PMID: 18663599.
    Citations: 68     Fields:    Translation:Humans
  160. Lu MT, Cai T, Ersoy H, Whitmore AG, Levit NA, Goldhaber SZ, Rybicki FJ. Comparison of ECG-gated versus non-gated CT ventricular measurements in thirty patients with acute pulmonary embolism. Int J Cardiovasc Imaging. 2009 Jan; 25(1):101-7. PMID: 18626787.
    Citations: 14     Fields:    Translation:Humans
  161. Rybicki FJ, Otero HJ, Steigner ML, Vorobiof G, Nallamshetty L, Mitsouras D, Ersoy H, Mather RT, Judy PF, Cai T, Coyner K, Schultz K, Whitmore AG, Di Carli MF. Initial evaluation of coronary images from 320-detector row computed tomography. Int J Cardiovasc Imaging. 2008 Jun; 24(5):535-46. PMID: 18368512.
    Citations: 156     Fields:    Translation:Humans
  162. Ware JH, Cai T. Comments on 'Evaluating the added predictive ability of a new marker: From area under the ROC curve to reclassification and beyond' by M. J. Pencina et al., Statistics in Medicine (DOI: 10.1002/sim.2929). Stat Med. 2008 Jan 30; 27(2):185-7. PMID: 17668917.
    Citations: 1     Fields:    Translation:Humans
  163. Lu MT, Cai T, Ersoy H, Whitmore AG, Quiroz R, Goldhaber SZ, Rybicki FJ. Interval increase in right-left ventricular diameter ratios at CT as a predictor of 30-day mortality after acute pulmonary embolism: initial experience. Radiology. 2008 Jan; 246(1):281-7. PMID: 18096540.
    Citations: 10     Fields:    Translation:Humans
  164. Zheng Y, Cai T, Pepe MS, Levy WC. Time-dependent Predictive Values of Prognostic Biomarkers with Failure Time Outcome. J Am Stat Assoc. 2008; 103(481):362-368. PMID: 19655041.
    Citations: 17     
  165. Cai T, Cheng S. Robust combination of multiple diagnostic tests for classifying censored event times. Biostatistics. 2008 Apr; 9(2):216-33. PMID: 18056687.
    Citations: 9     Fields:    Translation:Humans
  166. MacKenzie JD, Nazario-Larrieu J, Cai T, Ledbetter MS, Duran-Mendicuti MA, Judy PF, Rybicki FJ. Reduced-dose CT: effect on reader evaluation in detection of pulmonary embolism. AJR Am J Roentgenol. 2007 Dec; 189(6):1371-9. PMID: 18029873.
    Citations: 10     Fields:    Translation:Humans
  167. Ersoy H, Goldhaber SZ, Cai T, Luu T, Rosebrook J, Mulkern R, Rybicki F. Time-resolved MR angiography: a primary screening examination of patients with suspected pulmonary embolism and contraindications to administration of iodinated contrast material. AJR Am J Roentgenol. 2007 May; 188(5):1246-54. PMID: 17449767.
    Citations: 16     Fields:    Translation:HumansPHPublic Health
  168. Cai T, Zheng Y. Model checking for ROC regression analysis. Biometrics. 2007 Mar; 63(1):152-63. PMID: 17447940.
    Citations: 4     Fields:    Translation:Humans
  169. Chuang SK, Cai T. Predicting clustered dental implant survival using frailty methods. J Dent Res. 2006 Dec; 85(12):1147-51. PMID: 17122171; PMCID: PMC2443684.
    Citations: 2     Fields:    Translation:Humans
  170. Pepe MS, Cai T, Longton G. Combining predictors for classification using the area under the receiver operating characteristic curve. Biometrics. 2006 Mar; 62(1):221-9. PMID: 16542249.
    Citations: 55     Fields:    Translation:Humans
  171. Zheng Y, Cai T, Feng Z. Application of the time-dependent ROC curves for prognostic accuracy with multiple biomarkers. Biometrics. 2006 Mar; 62(1):279-87. PMID: 16542256.
    Citations: 25     Fields:    Translation:Humans
  172. Cai T, Gilbert PB, Self SG. Joint inferences on vaccine efficacy against infection and disease with application to the first HIV vaccine efficacy trial. J Biopharm Stat. 2006; 16(4):517-38. PMID: 16892911.
    Citations:    Fields:    Translation:Humans
  173. Cai T, Pepe MS, Zheng Y, Lumley T, Jenny NS. The sensitivity and specificity of markers for event times. Biostatistics. 2006 Apr; 7(2):182-97. PMID: 16079162.
    Citations: 15     Fields:    Translation:Humans
  174. Chuang SK, Cai T, Douglass CW, Wei LJ, Dodson TB. Frailty approach for the analysis of clustered failure time observations in dental research. J Dent Res. 2005 Jan; 84(1):54-8. PMID: 15615876.
    Citations: 8     Fields:    Translation:Humans
  175. Cai T, Moskowitz CS. Semi-parametric estimation of the binormal ROC curve for a continuous diagnostic test. Biostatistics. 2004 Oct; 5(4):573-86. PMID: 15475420.
    Citations: 12     Fields:    Translation:Humans
  176. Pepe MS, Cai T. The analysis of placement values for evaluating discriminatory measures. Biometrics. 2004 Jun; 60(2):528-35. PMID: 15180681.
    Citations: 18     Fields:    Translation:Humans
  177. Cai T. Semi-parametric ROC regression analysis with placement values. Biostatistics. 2004 Jan; 5(1):45-60. PMID: 14744827.
    Citations: 6     Fields:    Translation:Humans
  178. Cai T, Betensky RA. Hazard regression for interval-censored data with penalized spline. Biometrics. 2003 Sep; 59(3):570-9. PMID: 14601758.
    Citations: 15     Fields:    Translation:Humans
  179. Kaplan R, Zhang T, Hernandez M, Gan FX, Wright SD, Waters MG, Cai TQ. Regulation of the angiopoietin-like protein 3 gene by LXR. J Lipid Res. 2003 Jan; 44(1):136-43. PMID: 12518032.
    Citations: 15     Fields:    Translation:HumansAnimalsCells
  180. Kaplan R, Gan X, Menke JG, Wright SD, Cai TQ. Bacterial lipopolysaccharide induces expression of ABCA1 but not ABCG1 via an LXR-independent pathway. J Lipid Res. 2002 Jun; 43(6):952-9. PMID: 12032171.
    Citations: 15     Fields:    Translation:HumansAnimalsCells
  181. Rogus JJ, Cai T, Wei LJ. Issues in genomic screening: critical values, sample sizes, and the ability to detect linkage. Genet Epidemiol. 1999; 17 Suppl 1:S697-701. PMID: 10597516.
    Citations:    Fields:    Translation:Humans
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Funded by the NIH/NCATS Clinical and Translational Science Award (CTSA) program, grant number UL1TR001102, and through institutional support from Harvard University, Harvard Medical School, Harvard T.H. Chan School of Public Health, Beth Israel Deaconess Medical Center, Boston Children's Hospital, Brigham and Women's Hospital, Massachusetts General Hospital and the Dana Farber Cancer Institute.