Contact, publication, and social network information about Harvard faculty and fellows. Harvard Catalyst Profiles
Last Name

profileJames Morgan Cunningham, M.D.

TitleAssociate Professor of Medicine (Microbiology and Molecular Genetics)
InstitutionBrigham and Women's Hospital
AddressChildren's Hospital
Hematology, Karp Bldg, Rm 5213
1 Blackfan Circle
Boston MA 02115
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Collapse Mentoring 
Collapse completed student projects
Role of Vitamin D Metabolism in the Pathophisiology of Rotator Cuff Arthropathy
Summer, 06/06/11 - 08/22/11

Collapse Research 
Collapse research activities and funding
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
U19AI109740     (WHELAN, SEAN PJ)Mar 1, 2014 - Feb 28, 2019
Small molecule inhibitors of enveloped virus entry
Role: Co-Principal Investigator

R01CA104266     (CUNNINGHAM, JAMES M)Sep 10, 2004 - Jun 30, 2010
Alternative Entry Mechanism for Pathogenic Retroviruses
Role: Principal Investigator

U54AI057159     (KASPER, DENNIS L.)Sep 4, 2003 - Feb 28, 2014
New England Regional Center of Excellence in Biodefense and Emerging Infectious D
Role: Co-Principal Investigator

R01CA061246     (CUNNINGHAM, JAMES M)Jul 1, 1993 - Apr 30, 2003
Role: Principal Investigator

R29CA047075     (CUNNINGHAM, JAMES M)Jul 8, 1988 - Jun 30, 1993
Role: Principal Investigator

Collapse Bibliographic 
Collapse selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
List All   |   Timeline
  1. Wang MK, Lim SY, Lee SM, Cunningham JM. Biochemical Basis for Increased Activity of Ebola Glycoprotein in the 2013-16 Epidemic. Cell Host Microbe. 2017 Mar 08; 21(3):367-375. PMID: 28238624.
    View in: PubMed
  2. Shedlock DJ, Bailey MA, Popernack PM, Cunningham JM, Burton DR, Sullivan NJ. Antibody-mediated neutralization of Ebola virus can occur by two distinct mechanisms. Virology. 2010 Jun 05; 401(2):228-35. PMID: 20304456; PMCID: PMC3351102.
  3. Smith JG, Cunningham JM. Receptor-induced thiolate couples Env activation to retrovirus fusion and infection. PLoS Pathog. 2007 Dec 21; 3(12):e198. PMID: 18260686; PMCID: PMC2151085.
  4. Chandran K, Sullivan NJ, Felbor U, Whelan SP, Cunningham JM. Endosomal proteolysis of the Ebola virus glycoprotein is necessary for infection. Science. 2005 Jun 10; 308(5728):1643-5. PMID: 15831716; PMCID: PMC4797943.
  5. Schuurmans C, Armant O, Nieto M, Stenman JM, Britz O, Klenin N, Brown C, Langevin LM, Seibt J, Tang H, Cunningham JM, Dyck R, Walsh C, Campbell K, Polleux F, Guillemot F. Sequential phases of cortical specification involve Neurogenin-dependent and -independent pathways. EMBO J. 2004 Jul 21; 23(14):2892-902. PMID: 15229646; PMCID: PMC514942.
  6. Smith JG, Mothes W, Blacklow SC, Cunningham JM. The mature avian leukosis virus subgroup A envelope glycoprotein is metastable, and refolding induced by the synergistic effects of receptor binding and low pH is coupled to infection. J Virol. 2004 Feb; 78(3):1403-10. PMID: 14722295; PMCID: PMC321377.
  7. Sherer NM, Lehmann MJ, Jimenez-Soto LF, Ingmundson A, Horner SM, Cicchetti G, Allen PG, Pypaert M, Cunningham JM, Mothes W. Visualization of retroviral replication in living cells reveals budding into multivesicular bodies. Traffic. 2003 Nov; 4(11):785-801. PMID: 14617360.
    View in: PubMed
  8. Wensel DL, Li W, Cunningham JM. A virus-virus interaction circumvents the virus receptor requirement for infection by pathogenic retroviruses. J Virol. 2003 Mar; 77(6):3460-9. PMID: 12610121; PMCID: PMC149514.
  9. Barnett AL, Wensel DL, Li W, Fass D, Cunningham JM. Structure and mechanism of a coreceptor for infection by a pathogenic feline retrovirus. J Virol. 2003 Feb; 77(4):2717-29. PMID: 12552012; PMCID: PMC141074.
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