Harvard Catalyst Profiles

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James Morgan Cunningham, M.D.


Role of Vitamin D Metabolism in the Pathophisiology of Rotator Cuff Arthropathy
Summer, 06/06/11 - 08/22/11

The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. U19AI109740 (WHELAN, SEAN PJ) Mar 1, 2014 - Feb 28, 2019
    Small molecule inhibitors of enveloped virus entry
    Role: Co-Principal Investigator
  2. R01CA104266 (CUNNINGHAM, JAMES M) Sep 10, 2004 - Jun 30, 2010
    Alternative Entry Mechanism for Pathogenic Retroviruses
    Role: Principal Investigator
  3. U54AI057159 (KASPER, DENNIS L.) Sep 4, 2003 - Feb 28, 2015
    New England Regional Center of Excellence in Biodefense and Emerging Infectious D
    Role: Co-Principal Investigator
  4. R01CA061246 (CUNNINGHAM, JAMES M) Jul 1, 1993 - Apr 30, 2003
    Role: Principal Investigator
  5. R29CA047075 (CUNNINGHAM, JAMES M) Jul 8, 1988 - Jun 30, 1993
    Role: Principal Investigator

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Sivakumaren SC, Shim H, Zhang T, Ferguson FM, Lundquist MR, Browne CM, Seo HS, Paddock MN, Manz TD, Jiang B, Hao MF, Krishnan P, Wang DG, Yang TJ, Kwiatkowski NP, Ficarro SB, Cunningham JM, Marto JA, Dhe-Paganon S, Cantley LC, Gray NS. Targeting the PI5P4K Lipid Kinase Family in Cancer Using Covalent Inhibitors. Cell Chem Biol. 2020 05 21; 27(5):525-537.e6. PMID: 32130941.
    Citations: 11     Fields:    Translation:HumansCells
  2. Wang MK, Ren T, Liu H, Lim SY, Lee K, Honko A, Zhou H, Dyall J, Hensley L, Gartin AK, Cunningham JM. Critical role for cholesterol in Lassa fever virus entry identified by a novel small molecule inhibitor targeting the viral receptor LAMP1. PLoS Pathog. 2018 09; 14(9):e1007322. PMID: 30265711; PMCID: PMC6179309.
    Citations: 5     Fields:    Translation:HumansAnimalsCells
  3. Liu H, Tian Y, Lee K, Krishnan P, Wang MK, Whelan S, Mevers E, Soloveva V, Dedic B, Liu X, Cunningham JM. Identification of Potent Ebola Virus Entry Inhibitors with Suitable Properties for in Vivo Studies. J Med Chem. 2018 Jul 26; 61(14):6293-6307. PMID: 29920098.
    Citations: 5     Fields:    Translation:HumansAnimalsCells
  4. Wang MK, Lim SY, Lee SM, Cunningham JM. Biochemical Basis for Increased Activity of Ebola Glycoprotein in the 2013-16 Epidemic. Cell Host Microbe. 2017 Mar 08; 21(3):367-375. PMID: 28238624; PMCID: PMC5735838.
    Citations: 29     Fields:    Translation:CellsPHPublic Health
  5. Côté M, Cunningham JM. L'entrée du virus Ébola et Marburg : interaction entre la glycoprotéine virale et les facteurs cellulaires. Virologie (Montrouge). 2012 Jun 01; 16(3):168-177. PMID: 33065873.
    Citations:    Fields:    
  6. Shedlock DJ, Bailey MA, Popernack PM, Cunningham JM, Burton DR, Sullivan NJ. Antibody-mediated neutralization of Ebola virus can occur by two distinct mechanisms. Virology. 2010 Jun 05; 401(2):228-35. PMID: 20304456.
    Citations: 51     Fields:    Translation:HumansAnimalsCells
  7. Smith JG, Cunningham JM. Receptor-induced thiolate couples Env activation to retrovirus fusion and infection. PLoS Pathog. 2007 Dec 21; 3(12):e198. PMID: 18260686.
    Citations: 19     Fields:    Translation:HumansCells
  8. Chandran K, Sullivan NJ, Felbor U, Whelan SP, Cunningham JM. Endosomal proteolysis of the Ebola virus glycoprotein is necessary for infection. Science. 2005 Jun 10; 308(5728):1643-5. PMID: 15831716.
    Citations: 494     Fields:    Translation:AnimalsCells
  9. Schuurmans C, Armant O, Nieto M, Stenman JM, Britz O, Klenin N, Brown C, Langevin LM, Seibt J, Tang H, Cunningham JM, Dyck R, Walsh C, Campbell K, Polleux F, Guillemot F. Sequential phases of cortical specification involve Neurogenin-dependent and -independent pathways. EMBO J. 2004 Jul 21; 23(14):2892-902. PMID: 15229646; PMCID: PMC514942.
    Citations: 166     Fields:    Translation:AnimalsCells
  10. Smith JG, Mothes W, Blacklow SC, Cunningham JM. The mature avian leukosis virus subgroup A envelope glycoprotein is metastable, and refolding induced by the synergistic effects of receptor binding and low pH is coupled to infection. J Virol. 2004 Feb; 78(3):1403-10. PMID: 14722295; PMCID: PMC321377.
    Citations: 41     Fields:    Translation:HumansAnimalsCells
  11. Sherer NM, Lehmann MJ, Jimenez-Soto LF, Ingmundson A, Horner SM, Cicchetti G, Allen PG, Pypaert M, Cunningham JM, Mothes W. Visualization of retroviral replication in living cells reveals budding into multivesicular bodies. Traffic. 2003 Nov; 4(11):785-801. PMID: 14617360.
    Citations: 228     Fields:    Translation:HumansAnimalsCells
  12. Wensel DL, Li W, Cunningham JM. A virus-virus interaction circumvents the virus receptor requirement for infection by pathogenic retroviruses. J Virol. 2003 Mar; 77(6):3460-9. PMID: 12610121; PMCID: PMC149514.
    Citations: 17     Fields:    Translation:HumansAnimalsCells
  13. Barnett AL, Wensel DL, Li W, Fass D, Cunningham JM. Structure and mechanism of a coreceptor for infection by a pathogenic feline retrovirus. J Virol. 2003 Feb; 77(4):2717-29. PMID: 12552012; PMCID: PMC141074.
    Citations: 23     Fields:    Translation:HumansAnimalsCells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.