Harvard Catalyst Profiles

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Marianne Wessling-resnick, Ph.D.


The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. R25ES020722 (WESSLING-RESNICK, MARIANNE) Aug 8, 2011 - Apr 30, 2016
    Summer Intern Program (SIP) in Environmental Health Sciences
    Role: Principal Investigator
  2. R03DA027030 (WESSLING-RESNICK, MARIANNE) Sep 30, 2009 - Aug 31, 2012
    HFE: A Genetic Determinant of Olfactory Mn Absorption and Toxicity
    Role: Principal Investigator
  3. RC1DK086774 (WESSLING-RESNICK, MARIANNE) Sep 30, 2009 - Jul 31, 2012
    Ferristatin: A New Small Molecule Inhibitor of Iron Transport
    Role: Principal Investigator
  4. T32ES016645 (WESSLING-RESNICK, MARIANNE) Jul 1, 2008 - Jun 30, 2019
    Interdisciplinary Training in Genes and the Environment
    Role: Principal Investigator
  5. R21DA025573 (WESSLING-RESNICK, MARIANNE) May 1, 2008 - Apr 30, 2012
    Cannabinoid Inhibition of Divalent Metal Transporter-1 Activity
    Role: Principal Investigator

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Nnah IC, Wessling-Resnick M. Brain Iron Homeostasis: A Focus on Microglial Iron. Pharmaceuticals (Basel). 2018 Nov 23; 11(4). PMID: 30477086.
  2. Wessling-Resnick M. Crossing the Iron Gate: Why and How Transferrin Receptors Mediate Viral Entry. Annu Rev Nutr. 2018 08 21; 38:431-458. PMID: 29852086.
    Citations:    Fields:    
  3. Thompson KJ, Hein J, Baez A, Sosa JC, Wessling-Resnick M. Manganese transport and toxicity in polarized WIF-B hepatocytes. Am J Physiol Gastrointest Liver Physiol. 2018 09 01; 315(3):G351-G363. PMID: 29792530.
    Citations:    Fields:    
  4. Rodan LH, Hauptman M, D'Gama AM, Qualls AE, Cao S, Tuschl K, Al-Jasmi F, Hertecant J, Hayflick SJ, Wessling-Resnick M, Yang ET, Berry GT, Gropman A, Woolf AD, Agrawal PB. Novel founder intronic variant in SLC39A14 in two families causing Manganism and potential treatment strategies. Mol Genet Metab. 2018 06; 124(2):161-167. PMID: 29685658.
    Citations: 1     Fields:    
  5. McCarthy RC, Sosa JC, Gardeck AM, Baez AS, Lee CH, Wessling-Resnick M. Inflammation-induced iron transport and metabolism by brain microglia. J Biol Chem. 2018 05 18; 293(20):7853-7863. PMID: 29610275.
    Citations: 2     Fields:    Translation:AnimalsCells
  6. Wessling-Resnick M. Excess iron: considerations related to development and early growth. Am J Clin Nutr. 2017 Dec; 106(Suppl 6):1600S-1605S. PMID: 29070548.
    Citations: 1     Fields:    Translation:HumansCells
  7. Grillo AS, SantaMaria AM, Kafina MD, Cioffi AG, Huston NC, Han M, Seo YA, Yien YY, Nardone C, Menon AV, Fan J, Svoboda DC, Anderson JB, Hong JD, Nicolau BG, Subedi K, Gewirth AA, Wessling-Resnick M, Kim J, Paw BH, Burke MD. Restored iron transport by a small molecule promotes absorption and hemoglobinization in animals. Science. 2017 05 12; 356(6338):608-616. PMID: 28495746.
    Citations: 9     Fields:    Translation:HumansAnimalsCells
  8. Seo YA, Kumara R, Wetli H, Wessling-Resnick M. Regulation of divalent metal transporter-1 by serine phosphorylation. Biochem J. 2016 11 15; 473(22):4243-4254. PMID: 27681840.
    Citations: 2     Fields:    Translation:HumansCells
  9. Patchen B, Koppe T, Cheng A, Seo YA, Wessling-Resnick M, Fraenkel PG. Dietary supplementation with ipriflavone decreases hepatic iron stores in wild type mice. Blood Cells Mol Dis. 2016 09; 60:36-43. PMID: 27519943.
    Citations: 2     Fields:    Translation:Animals
  10. McCarthy RC, Lu DY, Alkhateeb A, Gardeck AM, Lee CH, Wessling-Resnick M. Characterization of a novel adult murine immortalized microglial cell line and its activation by amyloid-beta. J Neuroinflammation. 2016 Jan 27; 13:21. PMID: 26819091.
    Citations: 9     Fields:    Translation:AnimalsCells
  11. Seo YA, Elkhader JA, Wessling-Resnick M. Distribution of manganese and other biometals in flatiron mice. Biometals. 2016 Feb; 29(1):147-55. PMID: 26693922.
    Citations: 4     Fields:    Translation:HumansAnimals
  12. Wessling-Resnick M. Nramp1 and Other Transporters Involved in Metal Withholding during Infection. J Biol Chem. 2015 Jul 31; 290(31):18984-90. PMID: 26055722.
    Citations: 15     Fields:    Translation:HumansAnimals
  13. Alkhateeb AA, Buckett PD, Gardeck AM, Kim J, Byrne SL, Fraenkel PG, Wessling-Resnick M. The small molecule ferristatin II induces hepatic hepcidin expression in vivo and in vitro. Am J Physiol Gastrointest Liver Physiol. 2015 Jun 15; 308(12):G1019-26. PMID: 25907691.
    Citations: 5     Fields:    Translation:HumansAnimalsCells
  14. Seo YA, Wessling-Resnick M. Ferroportin deficiency impairs manganese metabolism in flatiron mice. FASEB J. 2015 Jul; 29(7):2726-33. PMID: 25782988.
    Citations: 7     Fields:    Translation:HumansAnimalsCells
  15. Kim J, Wessling-Resnick M. Iron and mechanisms of emotional behavior. J Nutr Biochem. 2014 Nov; 25(11):1101-1107. PMID: 25154570.
    Citations: 23     Fields:    Translation:HumansAnimals
  16. Veuthey T, Wessling-Resnick M. Pathophysiology of the Belgrade rat. Front Pharmacol. 2014; 5:82. PMID: 24795636.
    Citations: 5     
  17. Veuthey T, Hoffmann D, Vaidya VS, Wessling-Resnick M. Impaired renal function and development in Belgrade rats. Am J Physiol Renal Physiol. 2014 Feb 01; 306(3):F333-43. PMID: 24226520.
    Citations: 6     Fields:    Translation:Animals
  18. Zhen AW, Nguyen NH, Gibert Y, Motola S, Buckett P, Wessling-Resnick M, Fraenkel E, Fraenkel PG. The small molecule, genistein, increases hepcidin expression in human hepatocytes. Hepatology. 2013 Oct; 58(4):1315-25. PMID: 23703590.
    Citations: 19     Fields:    Translation:HumansAnimalsCells
  19. Byrne SL, Buckett PD, Kim J, Luo F, Sanford J, Chen J, Enns C, Wessling-Resnick M. Ferristatin II promotes degradation of transferrin receptor-1 in vitro and in vivo. PLoS One. 2013; 8(7):e70199. PMID: 23894616.
    Citations: 9     Fields:    Translation:HumansAnimalsCells
  20. Seo YA, Li Y, Wessling-Resnick M. Iron depletion increases manganese uptake and potentiates apoptosis through ER stress. Neurotoxicology. 2013 Sep; 38:67-73. PMID: 23764342.
    Citations: 12     Fields:    Translation:HumansAnimalsCells
  21. Kim J, Buckett PD, Wessling-Resnick M. Absorption of manganese and iron in a mouse model of hemochromatosis. PLoS One. 2013; 8(5):e64944. PMID: 23705020.
    Citations: 17     Fields:    Translation:Animals
  22. Jia X, Kim J, Veuthey T, Lee CH, Wessling-Resnick M. Glucose metabolism in the Belgrade rat, a model of iron-loading anemia. Am J Physiol Gastrointest Liver Physiol. 2013 Jun 15; 304(12):G1095-102. PMID: 23599042.
    Citations: 3     Fields:    Translation:AnimalsCells
  23. Patterson RE, Colditz GA, Hu FB, Schmitz KH, Ahima RS, Brownson RC, Carson KR, Chavarro JE, Chodosh LA, Gehlert S, Gill J, Glanz K, Haire-Joshu D, Herbst KL, Hoehner CM, Hovmand PS, Irwin ML, Jacobs LA, James AS, Jones LW, Kerr J, Kibel AS, King IB, Ligibel JA, Meyerhardt JA, Natarajan L, Neuhouser ML, Olefsky JM, Proctor EK, Redline S, Rock CL, Rosner B, Sarwer DB, Schwartz JS, Sears DD, Sesso HD, Stampfer MJ, Subramanian SV, Taveras EM, Tchou J, Thompson B, Troxel AB, Wessling-Resnick M, Wolin KY, Thornquist MD. The 2011-2016 Transdisciplinary Research on Energetics and Cancer (TREC) initiative: rationale and design. Cancer Causes Control. 2013 Apr; 24(4):695-704. PMID: 23378138.
    Citations: 17     Fields:    Translation:Humans
  24. Kim J, Jia X, Buckett PD, Liu S, Lee CH, Wessling-Resnick M. Iron loading impairs lipoprotein lipase activity and promotes hypertriglyceridemia. FASEB J. 2013 Apr; 27(4):1657-63. PMID: 23241313.
    Citations: 8     Fields:    Translation:Animals
  25. Byrne SL, Krishnamurthy D, Wessling-Resnick M. Pharmacology of iron transport. Annu Rev Pharmacol Toxicol. 2013; 53:17-36. PMID: 23020294.
    Citations: 4     Fields:    Translation:HumansAnimals
  26. Ruvin Kumara VM, Wessling-Resnick M. Olfactory ferric and ferrous iron absorption in iron-deficient rats. Am J Physiol Lung Cell Mol Physiol. 2012 Jun 15; 302(12):L1280-6. PMID: 22492739.
    Citations: 2     Fields:    Translation:AnimalsCells
  27. Kim J, Li Y, Buckett PD, Böhlke M, Thompson KJ, Takahashi M, Maher TJ, Wessling-Resnick M. Iron-responsive olfactory uptake of manganese improves motor function deficits associated with iron deficiency. PLoS One. 2012; 7(3):e33533. PMID: 22479410.
    Citations: 11     Fields:    Translation:Animals
  28. Kim J, Wessling-Resnick M. The Role of Iron Metabolism in Lung Inflammation and Injury. J Allergy Ther. 2012; 3(Suppl 4). PMID: 29226014.
  29. Ruvin Kumara VM, Wessling-Resnick M. Influence of Iron Deficiency on Olfactory Behavior in Weanling Rats. J Behav Brain Sci. 2012; 2(2). PMID: 29520328.
  30. Claus Henn B, Kim J, Wessling-Resnick M, Téllez-Rojo MM, Jayawardene I, Ettinger AS, Hernández-Avila M, Schwartz J, Christiani DC, Hu H, Wright RO. Associations of iron metabolism genes with blood manganese levels: a population-based study with validation data from animal models. Environ Health. 2011 Nov 10; 10:97. PMID: 22074419.
    Citations: 26     Fields:    Translation:HumansAnimals
  31. Johnson EE, Wessling-Resnick M. Iron metabolism and the innate immune response to infection. Microbes Infect. 2012 Mar; 14(3):207-16. PMID: 22033148.
    Citations: 52     Fields:    Translation:HumansAnimalsCells
  32. Li Y, Kim J, Buckett PD, Böhlke M, Maher TJ, Wessling-Resnick M. Severe postnatal iron deficiency alters emotional behavior and dopamine levels in the prefrontal cortex of young male rats. J Nutr. 2011 Dec; 141(12):2133-8. PMID: 22013197.
    Citations: 6     Fields:    Translation:AnimalsCells
  33. Molina RM, Phattanarudee S, Kim J, Thompson K, Wessling-Resnick M, Maher TJ, Brain JD. Ingestion of Mn and Pb by rats during and after pregnancy alters iron metabolism and behavior in offspring. Neurotoxicology. 2011 Aug; 32(4):413-22. PMID: 21458486.
    Citations: 13     Fields:    Translation:AnimalsPHPublic Health
  34. Burpee T, Mitchell P, Fishman D, Islam S, Nemeth E, Westerman M, Wessling-Resnick M, Grand RJ. Intestinal ferroportin expression in pediatric Crohn's disease. Inflamm Bowel Dis. 2011 Feb; 17(2):524-31. PMID: 20564534.
    Citations: 2     Fields:    Translation:Humans
  35. Kim J, Molina RM, Donaghey TC, Buckett PD, Brain JD, Wessling-Resnick M. Influence of DMT1 and iron status on inflammatory responses in the lung. Am J Physiol Lung Cell Mol Physiol. 2011 Apr; 300(4):L659-65. PMID: 21278260.
    Citations: 11     Fields:    Translation:AnimalsCells
  36. Johnson EE, Sandgren A, Cherayil BJ, Murray M, Wessling-Resnick M. Role of ferroportin in macrophage-mediated immunity. Infect Immun. 2010 Dec; 78(12):5099-106. PMID: 20837712.
    Citations: 16     Fields:    Translation:AnimalsCells
  37. Wessling-Resnick M. Iron homeostasis and the inflammatory response. Annu Rev Nutr. 2010 Aug 21; 30:105-22. PMID: 20420524.
    Citations: 62     Fields:    Translation:Humans
  38. Deb S, Johnson EE, Robalinho-Teixeira RL, Wessling-Resnick M. Modulation of intracellular iron levels by oxidative stress implicates a novel role for iron in signal transduction. Biometals. 2009 Oct; 22(5):855-62. PMID: 19190985.
    Citations: 12     Fields:    Translation:HumansCells
  39. Buckett PD, Wessling-Resnick M. Small molecule inhibitors of divalent metal transporter-1. Am J Physiol Gastrointest Liver Physiol. 2009 Apr; 296(4):G798-804. PMID: 19179627.
    Citations: 14     Fields:    Translation:HumansCells
  40. Collins JF, Wessling-Resnick M, Knutson MD. Hepcidin regulation of iron transport. J Nutr. 2008 Nov; 138(11):2284-8. PMID: 18936232.
    Citations: 24     Fields:    Translation:Humans
  41. Wang L, Johnson EE, Shi HN, Walker WA, Wessling-Resnick M, Cherayil BJ. Attenuated inflammatory responses in hemochromatosis reveal a role for iron in the regulation of macrophage cytokine translation. J Immunol. 2008 Aug 15; 181(4):2723-31. PMID: 18684963.
    Citations: 51     Fields:    Translation:AnimalsCells
  42. Wessling-Resnick M. The irony of host defense. Blood. 2008 Aug 01; 112(3):460. PMID: 18650460.
    Citations:    Fields:    
  43. Horonchik L, Wessling-Resnick M. The small-molecule iron transport inhibitor ferristatin/NSC306711 promotes degradation of the transferrin receptor. Chem Biol. 2008 Jul 21; 15(7):647-53. PMID: 18635001.
    Citations: 14     Fields:    Translation:HumansCells
  44. Thompson K, Molina RM, Donaghey T, Brain JD, Wessling-Resnick M. Iron absorption by Belgrade rat pups during lactation. Am J Physiol Gastrointest Liver Physiol. 2007 Sep; 293(3):G640-4. PMID: 17640977.
    Citations: 7     Fields:    Translation:Animals
  45. Johnson EE, Wessling-Resnick M. Flatiron mice and ferroportin disease. Nutr Rev. 2007 Jul; 65(7):341-5. PMID: 17695375.
    Citations: 3     Fields:    Translation:HumansAnimals
  46. Thompson K, Molina RM, Brain JD, Wessling-Resnick M. Belgrade rats display liver iron loading. J Nutr. 2006 Dec; 136(12):3010-4. PMID: 17116712.
    Citations: 11     Fields:    Translation:Animals
  47. Thompson K, Molina RM, Donaghey T, Schwob JE, Brain JD, Wessling-Resnick M. Olfactory uptake of manganese requires DMT1 and is enhanced by anemia. FASEB J. 2007 Jan; 21(1):223-30. PMID: 17116743.
    Citations: 41     Fields:    Translation:Animals
  48. Wetli HA, Buckett PD, Wessling-Resnick M. Small-molecule screening identifies the selanazal drug ebselen as a potent inhibitor of DMT1-mediated iron uptake. Chem Biol. 2006 Sep; 13(9):965-72. PMID: 16984886.
    Citations: 18     Fields:    Translation:HumansCells
  49. Chlosta S, Fishman DS, Harrington L, Johnson EE, Knutson MD, Wessling-Resnick M, Cherayil BJ. The iron efflux protein ferroportin regulates the intracellular growth of Salmonella enterica. Infect Immun. 2006 May; 74(5):3065-7. PMID: 16622252.
    Citations: 51     Fields:    Translation:AnimalsCells
  50. Heilig EA, Thompson KJ, Molina RM, Ivanov AR, Brain JD, Wessling-Resnick M. Manganese and iron transport across pulmonary epithelium. Am J Physiol Lung Cell Mol Physiol. 2006 Jun; 290(6):L1247-59. PMID: 16428268.
    Citations: 16     Fields:    Translation:AnimalsCells
  51. Wessling-Resnick M. Iron imports. III. Transfer of iron from the mucosa into circulation. Am J Physiol Gastrointest Liver Physiol. 2006 Jan; 290(1):G1-6. PMID: 16354771.
    Citations: 19     Fields:    Translation:Humans
  52. Brain JD, Heilig E, Donaghey TC, Knutson MD, Wessling-Resnick M, Molina RM. Effects of iron status on transpulmonary transport and tissue distribution of Mn and Fe. Am J Respir Cell Mol Biol. 2006 Mar; 34(3):330-7. PMID: 16340001.
    Citations: 13     Fields:    Translation:AnimalsCells
  53. Yin J, Lin AJ, Buckett PD, Wessling-Resnick M, Golan DE, Walsh CT. Single-cell FRET imaging of transferrin receptor trafficking dynamics by Sfp-catalyzed, site-specific protein labeling. Chem Biol. 2005 Sep; 12(9):999-1006. PMID: 16183024.
    Citations: 11     Fields:    Translation:Cells
  54. Bergqvist SW, Sandberg AS, Andlid T, Wessling-Resnick M. Lactic acid decreases Fe(II) and Fe(III) retention but increases Fe(III) transepithelial transfer by Caco-2 cells. J Agric Food Chem. 2005 Aug 24; 53(17):6919-23. PMID: 16104821.
    Citations: 2     Fields:    Translation:HumansCells
  55. Thompson K, Molina R, Donaghey T, Brain JD, Wessling-Resnick M. The influence of high iron diet on rat lung manganese absorption. Toxicol Appl Pharmacol. 2006 Jan 01; 210(1-2):17-23. PMID: 15993455.
    Citations: 16     Fields:    Translation:AnimalsCells
  56. Knutson MD, Oukka M, Koss LM, Aydemir F, Wessling-Resnick M. Iron release from macrophages after erythrophagocytosis is up-regulated by ferroportin 1 overexpression and down-regulated by hepcidin. Proc Natl Acad Sci U S A. 2005 Feb 01; 102(5):1324-8. PMID: 15665091.
    Citations: 122     Fields:    Translation:HumansAnimalsCells
  57. Heilig E, Molina R, Donaghey T, Brain JD, Wessling-Resnick M. Pharmacokinetics of pulmonary manganese absorption: evidence for increased susceptibility to manganese loading in iron-deficient rats. Am J Physiol Lung Cell Mol Physiol. 2005 May; 288(5):L887-93. PMID: 15618452.
    Citations: 15     Fields:    Translation:Animals
  58. Simpson JC, Griffiths G, Wessling-Resnick M, Fransen JA, Bennett H, Jones AT. A role for the small GTPase Rab21 in the early endocytic pathway. J Cell Sci. 2004 Dec 15; 117(Pt 26):6297-311. PMID: 15561770.
    Citations: 49     Fields:    Translation:HumansCells
  59. Robb A, Wessling-Resnick M. Regulation of transferrin receptor 2 protein levels by transferrin. Blood. 2004 Dec 15; 104(13):4294-9. PMID: 15319276.
    Citations: 51     Fields:    Translation:HumansAnimalsCells
  60. Robb AD, Ericsson M, Wessling-Resnick M. Transferrin receptor 2 mediates a biphasic pattern of transferrin uptake associated with ligand delivery to multivesicular bodies. Am J Physiol Cell Physiol. 2004 Dec; 287(6):C1769-75. PMID: 15317665.
    Citations: 13     Fields:    Translation:HumansCells
  61. Nieland TJ, Feng Y, Brown JX, Chuang TD, Buckett PD, Wang J, Xie XS, McGraw TE, Kirchhausen T, Wessling-Resnick M. Chemical genetic screening identifies sulfonamides that raise organellar pH and interfere with membrane traffic. Traffic. 2004 Jul; 5(7):478-92. PMID: 15180825.
    Citations: 9     Fields:    Translation:HumansAnimalsCells
  62. Knutson M, Menzies S, Connor J, Wessling-Resnick M. Developmental, regional, and cellular expression of SFT/UbcH5A and DMT1 mRNA in brain. J Neurosci Res. 2004 Jun 01; 76(5):633-41. PMID: 15139022.
    Citations: 6     Fields:    Translation:HumansAnimals
  63. Brown JX, Buckett PD, Wessling-Resnick M. Identification of small molecule inhibitors that distinguish between non-transferrin bound iron uptake and transferrin-mediated iron transport. Chem Biol. 2004 Mar; 11(3):407-16. PMID: 15123270.
    Citations: 10     Fields:    Translation:HumansCells
  64. Chung J, Prohaska JR, Wessling-Resnick M. Ferroportin-1 is not upregulated in copper-deficient mice. J Nutr. 2004 Mar; 134(3):517-21. PMID: 14988440.
    Citations: 9     Fields:    Translation:AnimalsCells
  65. Chung J, Haile DJ, Wessling-Resnick M. Copper-induced ferroportin-1 expression in J774 macrophages is associated with increased iron efflux. Proc Natl Acad Sci U S A. 2004 Mar 02; 101(9):2700-5. PMID: 14973193.
    Citations: 16     Fields:    Translation:AnimalsCells
  66. Knutson MD, Vafa MR, Haile DJ, Wessling-Resnick M. Iron loading and erythrophagocytosis increase ferroportin 1 (FPN1) expression in J774 macrophages. Blood. 2003 Dec 01; 102(12):4191-7. PMID: 12907459.
    Citations: 63     Fields:    Translation:HumansAnimalsCells
  67. Chung J, Wessling-Resnick M. Molecular mechanisms and regulation of iron transport. Crit Rev Clin Lab Sci. 2003 Apr; 40(2):151-82. PMID: 12755454.
    Citations: 13     Fields:    Translation:HumansAnimalsCells
  68. Knutson M, Wessling-Resnick M. Iron metabolism in the reticuloendothelial system. Crit Rev Biochem Mol Biol. 2003; 38(1):61-88. PMID: 12641343.
    Citations: 71     Fields:    Translation:HumansAnimalsCells
  69. Wessling-Resnick M. A possible link between hepcidin and regulation of dietary iron absorption. Nutr Rev. 2002 Nov; 60(11):371-4. PMID: 12462520.
    Citations: 2     Fields:    Translation:HumansAnimalsCells
  70. Wessling-Resnick M. Understanding copper uptake at the molecular level. Nutr Rev. 2002 Jun; 60(6):177-9. PMID: 12078916.
    Citations:    Fields:    Translation:HumansAnimals
  71. Han O, Wessling-Resnick M. Copper repletion enhances apical iron uptake and transepithelial iron transport by Caco-2 cells. Am J Physiol Gastrointest Liver Physiol. 2002 Mar; 282(3):G527-33. PMID: 11842003.
    Citations: 12     Fields:    Translation:HumansCells
  72. Aisen P, Enns C, Wessling-Resnick M. Chemistry and biology of eukaryotic iron metabolism. Int J Biochem Cell Biol. 2001 Oct; 33(10):940-59. PMID: 11470229.
    Citations: 122     Fields:    Translation:HumansAnimalsCells
  73. Quellhorst GJ, Allen CM, Wessling-Resnick M. Modification of Rab5 with a photoactivatable analog of geranylgeranyl diphosphate. J Biol Chem. 2001 Nov 02; 276(44):40727-33. PMID: 11522782.
    Citations: 3     Fields:    Translation:AnimalsCells
  74. Knutson MD, Levy JE, Andrews NC, Wessling-Resnick M. Expression of stimulator of Fe transport is not enhanced in Hfe knockout mice. J Nutr. 2001 May; 131(5):1459-64. PMID: 11340100.
    Citations: 2     Fields:    Translation:Animals
  75. Wessling-Resnick M. Iron transport. Annu Rev Nutr. 2000; 20:129-51. PMID: 10940329.
    Citations: 14     Fields:    Translation:HumansCellsPHPublic Health
  76. Jones AT, Spiro DJ, Kirchhausen T, Melançon P, Wessling-Resnick M. Studies on the inhibition of endosome fusion by GTPgammaS-bound ARF. J Cell Sci. 1999 Oct; 112 ( Pt 20):3477-85. PMID: 10504296.
    Citations: 1     Fields:    Translation:HumansCells
  77. Akompong T, Ramm E, Chang C, Yu ZK, Wessling-Resnick M. Immunological analysis of beta-thalassemic mouse intestinal proteins reveals up-regulation of sucrase-isomaltase in response to iron overload. J Nutr. 1999 May; 129(5):949-52. PMID: 10222384.
    Citations: 1     Fields:    Translation:HumansAnimalsCells
  78. Aisen P, Wessling-Resnick M, Leibold EA. Iron metabolism. Curr Opin Chem Biol. 1999 Apr; 3(2):200-6. PMID: 10226041.
    Citations: 37     Fields:    Translation:HumansCells
  79. Wessling-Resnick M. Biochemistry of iron uptake. Crit Rev Biochem Mol Biol. 1999; 34(5):285-314. PMID: 10565676.
    Citations: 14     Fields:    Translation:HumansAnimals
  80. Gutierrez JA, Yu J, Wessling-Resnick M. Characterization and chromosomal mapping of the human gene for SFT, a stimulator of Fe transport. Biochem Biophys Res Commun. 1998 Dec 30; 253(3):739-42. PMID: 9918797.
    Citations: 4     Fields:    Translation:HumansCells
  81. Yu J, Yu ZK, Wessling-Resnick M. Expression of SFT (stimulator of Fe transport) is enhanced by iron chelation in HeLa cells and by hemochromatosis in liver. J Biol Chem. 1998 Dec 25; 273(52):34675-8. PMID: 9856986.
    Citations: 2     Fields:    Translation:HumansCells
  82. Gutierrez JA, Inman RS, Akompong T, Yu J, Wessling-Resnick M. Metabolic depletion inhibits the uptake of nontransferrin-bound iron by K562 cells. J Cell Physiol. 1998 Dec; 177(4):585-92. PMID: 10092211.
    Citations: 1     Fields:    Translation:HumansCells
  83. Jones AT, Wessling-Resnick M. Inhibition of in vitro endosomal vesicle fusion activity by aminoglycoside antibiotics. J Biol Chem. 1998 Sep 25; 273(39):25301-9. PMID: 9737996.
    Citations: 3     Fields:    Translation:Cells
  84. Yu J, Wessling-Resnick M. Structural and functional analysis of SFT, a stimulator of Fe Transport. J Biol Chem. 1998 Aug 14; 273(33):21380-5. PMID: 9694900.
    Citations: 3     Fields:    Translation:HumansAnimalsCells
  85. Pan JY, Wessling-Resnick M. GEF-mediated GDP/GTP exchange by monomeric GTPases: a regulatory role for Mg2+? Bioessays. 1998 Jun; 20(6):516-21. PMID: 9699463.
    Citations: 13     Fields:    Translation:Animals
  86. Yu J, Wessling-Resnick M. Influence of copper depletion on iron uptake mediated by SFT, a stimulator of Fe transport. J Biol Chem. 1998 Mar 20; 273(12):6909-15. PMID: 9506995.
    Citations: 2     Fields:    Translation:HumansCells
  87. Gutierrez JA, Yu J, Rivera S, Wessling-Resnick M. Functional expression cloning and characterization of SFT, a stimulator of Fe transport. J Cell Biol. 1997 Nov 17; 139(4):895-905. PMID: 9362508.
    Citations: 10     Fields:    Translation:HumansAnimalsCells
  88. Green EG, Ramm E, Riley NM, Spiro DJ, Goldenring JR, Wessling-Resnick M. Rab11 is associated with transferrin-containing recycling compartments in K562 cells. Biochem Biophys Res Commun. 1997 Oct 20; 239(2):612-6. PMID: 9344879.
    Citations: 34     Fields:    Translation:HumansCells
  89. Yanachkov I, Pan JY, Wessling-Resnick M, Wright GE. Synthesis and effect of nonhydrolyzable xanthosine triphosphate derivatives on prenylation of Rab5D136N. Mol Pharmacol. 1997 Jan; 51(1):47-51. PMID: 9016345.
    Citations: 2     Fields:    Translation:Cells
  90. Barisani D, Wessling-Resnick M. Fe-nitrilotriacetic acid--binding proteins associated with rat liver plasma membranes. Hepatology. 1996 Oct; 24(4):934-8. PMID: 8855201.
    Citations:    Fields:    Translation:Animals
  91. Spiro DJ, Boll W, Kirchhausen T, Wessling-Resnick M. Wortmannin alters the transferrin receptor endocytic pathway in vivo and in vitro. Mol Biol Cell. 1996 Mar; 7(3):355-67. PMID: 8868465.
    Citations: 58     Fields:    Translation:HumansCells
  92. Pan JY, Sanford JC, Wessling-Resnick M. Influence of Mg2+ on the structure and function of Rab5. J Biol Chem. 1996 Jan 19; 271(3):1322-8. PMID: 8576119.
    Citations: 7     Fields:    Translation:Cells
  93. Gutierrez JA, Wessling-Resnick M. Molecular mechanisms of iron transport. Crit Rev Eukaryot Gene Expr. 1996; 6(1):1-14. PMID: 8882304.
    Citations: 2     Fields:    Translation:HumansAnimals
  94. Sanford JC, Yu J, Pan JY, Wessling-Resnick M. GDP dissociation inhibitor serves as a cytosolic acceptor for newly synthesized and prenylated Rab5. J Biol Chem. 1995 Nov 10; 270(45):26904-9. PMID: 7592935.
    Citations: 5     Fields:    Translation:HumansAnimalsCells
  95. Pan JY, Sanford JC, Wessling-Resnick M. Effect of guanine nucleotide binding on the intrinsic tryptophan fluorescence properties of Rab5. J Biol Chem. 1995 Oct 13; 270(41):24204-8. PMID: 7592625.
    Citations: 8     Fields:    Translation:Cells
  96. Hoffenberg S, Nikolova L, Pan JY, Daniel DS, Wessling-Resnick M, Knoll BJ, Dickey BF. Functional and structural interactions of the Rab5 D136N mutant with xanthine nucleotides. Biochem Biophys Res Commun. 1995 Oct 04; 215(1):241-9. PMID: 7575598.
    Citations: 9     Fields:    Translation:HumansCells
  97. Barisani D, Berg CL, Wessling-Resnick M, Gollan JL. Evidence for a low Km transporter for non-transferrin-bound iron in isolated rat hepatocytes. Am J Physiol. 1995 Oct; 269(4 Pt 1):G570-6. PMID: 7485509.
    Citations: 6     Fields:    Translation:Animals
  98. Akompong T, Inman RS, Wessling-Resnick M. Phorbol esters stimulate non-transferrin iron uptake by K562 cells. J Biol Chem. 1995 Sep 08; 270(36):20937-41. PMID: 7673117.
    Citations: 2     Fields:    Translation:HumansCells
  99. Spiro DJ, Taylor TC, Melançon P, Wessling-Resnick M. Cytosolic ADP-ribosylation factors are not required for endosome-endosome fusion but are necessary for GTP gamma S inhibition of fusion. J Biol Chem. 1995 Jun 09; 270(23):13693-7. PMID: 7775422.
    Citations: 1     Fields:    Translation:AnimalsCells
  100. Hoffenberg S, Sanford JC, Liu S, Daniel DS, Tuvin M, Knoll BJ, Wessling-Resnick M, Dickey BF. Biochemical and functional characterization of a recombinant GTPase, Rab5, and two of its mutants. J Biol Chem. 1995 Mar 10; 270(10):5048-56. PMID: 7890612.
    Citations: 19     Fields:    Translation:HumansCells
  101. Schonhorn JE, Akompong T, Wessling-Resnick M. Mechanism of transferrin receptor down-regulation in K562 cells in response to protein kinase C activation. J Biol Chem. 1995 Feb 24; 270(8):3698-705. PMID: 7876109.
    Citations: 3     Fields:    Translation:HumansCells
  102. Sanford JC, Foster L, Kapadia Z, Wessling-Resnick M. Analysis of the stoichiometry of Rab protein prenylation. Anal Biochem. 1995 Jan 20; 224(2):547-56. PMID: 7733457.
    Citations: 5     Fields:    Translation:HumansAnimalsCells
  103. Sanford JC, Pan Y, Wessling-Resnick M. Properties of Rab5 N-terminal domain dictate prenylation of C-terminal cysteines. Mol Biol Cell. 1995 Jan; 6(1):71-85. PMID: 7749197.
    Citations: 9     Fields:    Translation:HumansCells
  104. Wolf G, Wessling-Resnick M. An integrin-mobilferrin iron transport pathway in intestine and hematopoietic cells. Nutr Rev. 1994 Nov; 52(11):387-9. PMID: 7854652.
    Citations:    Fields:    Translation:HumansAnimals
  105. Inman RS, Coughlan MM, Wessling-Resnick M. Extracellular ferrireductase activity of K562 cells is coupled to transferrin-independent iron transport. Biochemistry. 1994 Oct 04; 33(39):11850-7. PMID: 7918403.
    Citations: 11     Fields:    Translation:HumansCells
  106. Schonhorn JE, Wessling-Resnick M. Brefeldin A down-regulates the transferrin receptor in K562 cells. Mol Cell Biochem. 1994 Jun 29; 135(2):159-69. PMID: 7838144.
    Citations: 10     Fields:    Translation:HumansCells
  107. Sanford JC, Pan Y, Wessling-Resnick M. Prenylation of Rab5 is dependent on guanine nucleotide binding. J Biol Chem. 1993 Nov 15; 268(32):23773-6. PMID: 8226909.
    Citations: 13     Fields:    Translation:AnimalsCells
  108. Inman RS, Wessling-Resnick M. Characterization of transferrin-independent iron transport in K562 cells. Unique properties provide evidence for multiple pathways of iron uptake. J Biol Chem. 1993 Apr 25; 268(12):8521-8. PMID: 8473296.
    Citations: 20     Fields:    Translation:HumansCells
  109. Wessling-Resnick M, Braell WA. Characterization of the mechanism of endocytic vesicle fusion in vitro. J Biol Chem. 1990 Oct 05; 265(28):16751-9. PMID: 2120206.
    Citations: 11     Fields:    Translation:HumansAnimalsCells
  110. Wessling-Resnick M, Braell WA. The sorting and segregation mechanism of the endocytic pathway is functional in a cell-free system. J Biol Chem. 1990 Jan 15; 265(2):690-9. PMID: 2153110.
    Citations: 5     Fields:    Translation:Cells
  111. Wessling-Resnick M, Johnson GL. Evidence for oligomeric forms of transducins alpha subunit: formation of intermolecular alpha-alpha disulfide linkages. Biochem Biophys Res Commun. 1989 Mar 15; 159(2):651-7. PMID: 2494995.
    Citations: 4     Fields:    Translation:AnimalsCells
  112. Dhanasekaran N, Wessling-Resnick M, Kelleher DJ, Johnson GL, Ruoho AE. Mapping of the carboxyl terminus within the tertiary structure of transducin's alpha subunit using the heterobifunctional cross-linking reagent, 125I-N-(3-iodo-4-azidophenylpropionamido-S-(2-thiopyridyl) cysteine. J Biol Chem. 1988 Dec 05; 263(34):17942-50. PMID: 3192520.
    Citations: 10     Fields:    Translation:Cells
  113. Wessling-Resnick M, Johnson GL. Transducin interactions with rhodopsin. Evidence for positive cooperative behavior. J Biol Chem. 1987 Sep 15; 262(26):12444-7. PMID: 3114258.
    Citations: 11     Fields:    Translation:Cells
  114. Wessling-Resnick M, Johnson GL. Kinetic and hydrodynamic properties of transducin: comparison of physical and structural parameters for GTP-binding regulatory proteins. Biochemistry. 1987 Jul 14; 26(14):4316-23. PMID: 3117101.
    Citations: 6     Fields:    Translation:AnimalsCells
  115. Wessling-Resnick M, Johnson GL. Allosteric behavior in transducin activation mediated by rhodopsin. Initial rate analysis of guanine nucleotide exchange. J Biol Chem. 1987 Mar 15; 262(8):3697-705. PMID: 3102494.
    Citations: 28     Fields:    Translation:AnimalsCells
  116. Aiello LP, Wessling-Resnick M, Pilch PF. Dipeptide metalloendoprotease substrates are glucose transport inhibitors and membrane structure perturbants. Biochemistry. 1986 Jul 01; 25(13):3944-50. PMID: 3527260.
    Citations: 3     Fields:    Translation:HumansAnimalsCells
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