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profileMarianne Wessling-resnick, Ph.D.

TitleProfessor of Nutritional Biochemistry
InstitutionHarvard T.H. Chan School of Public Health
DepartmentGenetics and Complex Diseases
AddressHarvard School of Public Health
Genetics & Complex Diseases, Bldg 2-123
655 Huntington Ave
Boston MA 02115
Phone617/432-3267
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Other Positions
TitleTutor in Biochemical Sciences
InstitutionFaculty of Arts & Sciences
DepartmentMCB Board of Tutor

TitleDirector of the Division of Biological Sciences
InstitutionHarvard T.H. Chan School of Public Health
DepartmentGenetics and Complex Diseases


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Collapse research activities and funding
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
R25ES020722     (WESSLING-RESNICK, MARIANNE)Aug 8, 2011 - Apr 30, 2016
NIH/NIEHS
Summer Intern Program (SIP) in Environmental Health Sciences
Role: Principal Investigator

R03DA027030     (WESSLING-RESNICK, MARIANNE)Sep 30, 2009 - Aug 31, 2012
NIH/NIDA
HFE: A Genetic Determinant of Olfactory Mn Absorption and Toxicity
Role: Principal Investigator

RC1DK086774     (WESSLING-RESNICK, MARIANNE)Sep 30, 2009 - Jul 31, 2012
NIH/NIDDK
Ferristatin: A New Small Molecule Inhibitor of Iron Transport
Role: Principal Investigator

T32ES016645     (WESSLING-RESNICK, MARIANNE)Jul 1, 2008 - Jun 30, 2019
NIH/NIEHS
Interdisciplinary Training in Genes and the Environment
Role: Principal Investigator

R21DA025573     (WESSLING-RESNICK, MARIANNE)May 1, 2008 - Apr 30, 2012
NIH/NIDA
Cannabinoid Inhibition of Divalent Metal Transporter-1 Activity
Role: Principal Investigator

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Collapse selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Grillo AS, SantaMaria AM, Kafina MD, Cioffi AG, Huston NC, Han M, Seo YA, Yien YY, Nardone C, Menon AV, Fan J, Svoboda DC, Anderson JB, Hong JD, Nicolau BG, Subedi K, Gewirth AA, Wessling-Resnick M, Kim J, Paw BH, Burke MD. Restored iron transport by a small molecule promotes absorption and hemoglobinization in animals. Science. 2017 May 12; 356(6338):608-616. PMID: 28495746.
    View in: PubMed
  2. Seo YA, Kumara R, Wetli H, Wessling-Resnick M. Regulation of divalent metal transporter-1 by serine phosphorylation. Biochem J. 2016 Nov 15; 473(22):4243-4254. PMID: 27681840.
    View in: PubMed
  3. Patchen B, Koppe T, Cheng A, Seo YA, Wessling-Resnick M, Fraenkel PG. Dietary supplementation with ipriflavone decreases hepatic iron stores in wild type mice. Blood Cells Mol Dis. 2016 Sep; 60:36-43. PMID: 27519943.
    View in: PubMed
  4. McCarthy RC, Lu DY, Alkhateeb A, Gardeck AM, Lee CH, Wessling-Resnick M. Characterization of a novel adult murine immortalized microglial cell line and its activation by amyloid-beta. J Neuroinflammation. 2016 Jan 27; 13:21. PMID: 26819091; PMCID: PMC4730646.
  5. Seo YA, Elkhader JA, Wessling-Resnick M. Distribution of manganese and other biometals in flatiron mice. Biometals. 2016 Feb; 29(1):147-55. PMID: 26693922; PMCID: PMC4735247.
  6. Wessling-Resnick M. Nramp1 and Other Transporters Involved in Metal Withholding during Infection. J Biol Chem. 2015 Jul 31; 290(31):18984-90. PMID: 26055722; PMCID: PMC4521020.
  7. Alkhateeb AA, Buckett PD, Gardeck AM, Kim J, Byrne SL, Fraenkel PG, Wessling-Resnick M. The small molecule ferristatin II induces hepatic hepcidin expression in vivo and in vitro. Am J Physiol Gastrointest Liver Physiol. 2015 Jun 15; 308(12):G1019-26. PMID: 25907691; PMCID: PMC4469869.
  8. Seo YA, Wessling-Resnick M. Ferroportin deficiency impairs manganese metabolism in flatiron mice. FASEB J. 2015 Jul; 29(7):2726-33. PMID: 25782988; PMCID: PMC4478796.
  9. Kim J, Wessling-Resnick M. Iron and mechanisms of emotional behavior. J Nutr Biochem. 2014 Nov; 25(11):1101-1107. PMID: 25154570; PMCID: PMC4253901.
  10. Veuthey T, Wessling-Resnick M. Pathophysiology of the Belgrade rat. Front Pharmacol. 2014; 5:82. PMID: 24795636; PMCID: PMC4000996.
  11. Veuthey T, Hoffmann D, Vaidya VS, Wessling-Resnick M. Impaired renal function and development in Belgrade rats. Am J Physiol Renal Physiol. 2014 Feb 01; 306(3):F333-43. PMID: 24226520; PMCID: PMC3920048.
  12. Zhen AW, Nguyen NH, Gibert Y, Motola S, Buckett P, Wessling-Resnick M, Fraenkel E, Fraenkel PG. The small molecule, genistein, increases hepcidin expression in human hepatocytes. Hepatology. 2013 Oct; 58(4):1315-25. PMID: 23703590; PMCID: PMC3770762.
  13. Byrne SL, Buckett PD, Kim J, Luo F, Sanford J, Chen J, Enns C, Wessling-Resnick M. Ferristatin II promotes degradation of transferrin receptor-1 in vitro and in vivo. PLoS One. 2013; 8(7):e70199. PMID: 23894616; PMCID: PMC3720890.
  14. Seo YA, Li Y, Wessling-Resnick M. Iron depletion increases manganese uptake and potentiates apoptosis through ER stress. Neurotoxicology. 2013 Sep; 38:67-73. PMID: 23764342; PMCID: PMC3770814.
  15. Kim J, Buckett PD, Wessling-Resnick M. Absorption of manganese and iron in a mouse model of hemochromatosis. PLoS One. 2013; 8(5):e64944. PMID: 23705020; PMCID: PMC3660331.
  16. Jia X, Kim J, Veuthey T, Lee CH, Wessling-Resnick M. Glucose metabolism in the Belgrade rat, a model of iron-loading anemia. Am J Physiol Gastrointest Liver Physiol. 2013 Jun 15; 304(12):G1095-102. PMID: 23599042; PMCID: PMC3680718.
  17. Patterson RE, Colditz GA, Hu FB, Schmitz KH, Ahima RS, Brownson RC, Carson KR, Chavarro JE, Chodosh LA, Gehlert S, Gill J, Glanz K, Haire-Joshu D, Herbst KL, Hoehner CM, Hovmand PS, Irwin ML, Jacobs LA, James AS, Jones LW, Kerr J, Kibel AS, King IB, Ligibel JA, Meyerhardt JA, Natarajan L, Neuhouser ML, Olefsky JM, Proctor EK, Redline S, Rock CL, Rosner B, Sarwer DB, Schwartz JS, Sears DD, Sesso HD, Stampfer MJ, Subramanian SV, Taveras EM, Tchou J, Thompson B, Troxel AB, Wessling-Resnick M, Wolin KY, Thornquist MD. The 2011-2016 Transdisciplinary Research on Energetics and Cancer (TREC) initiative: rationale and design. Cancer Causes Control. 2013 Apr; 24(4):695-704. PMID: 23378138; PMCID: PMC3602225.
  18. Kim J, Jia X, Buckett PD, Liu S, Lee CH, Wessling-Resnick M. Iron loading impairs lipoprotein lipase activity and promotes hypertriglyceridemia. FASEB J. 2013 Apr; 27(4):1657-63. PMID: 23241313; PMCID: PMC3606537.
  19. Byrne SL, Krishnamurthy D, Wessling-Resnick M. Pharmacology of iron transport. Annu Rev Pharmacol Toxicol. 2013; 53:17-36. PMID: 23020294; PMCID: PMC3837343.
  20. Ruvin Kumara VM, Wessling-Resnick M. Olfactory ferric and ferrous iron absorption in iron-deficient rats. Am J Physiol Lung Cell Mol Physiol. 2012 Jun 15; 302(12):L1280-6. PMID: 22492739; PMCID: PMC3379048.
  21. Kim J, Li Y, Buckett PD, Böhlke M, Thompson KJ, Takahashi M, Maher TJ, Wessling-Resnick M. Iron-responsive olfactory uptake of manganese improves motor function deficits associated with iron deficiency. PLoS One. 2012; 7(3):e33533. PMID: 22479410; PMCID: PMC3316579.
  22. Claus Henn B, Kim J, Wessling-Resnick M, Téllez-Rojo MM, Jayawardene I, Ettinger AS, Hernández-Avila M, Schwartz J, Christiani DC, Hu H, Wright RO. Associations of iron metabolism genes with blood manganese levels: a population-based study with validation data from animal models. Environ Health. 2011 Nov 10; 10:97. PMID: 22074419.
    View in: PubMed
  23. Johnson EE, Wessling-Resnick M. Iron metabolism and the innate immune response to infection. Microbes Infect. 2012 Mar; 14(3):207-16. PMID: 22033148; PMCID: PMC3270215.
  24. Li Y, Kim J, Buckett PD, Böhlke M, Maher TJ, Wessling-Resnick M. Severe postnatal iron deficiency alters emotional behavior and dopamine levels in the prefrontal cortex of young male rats. J Nutr. 2011 Dec; 141(12):2133-8. PMID: 22013197; PMCID: PMC3223871.
  25. Molina RM, Phattanarudee S, Kim J, Thompson K, Wessling-Resnick M, Maher TJ, Brain JD. Ingestion of Mn and Pb by rats during and after pregnancy alters iron metabolism and behavior in offspring. Neurotoxicology. 2011 Aug; 32(4):413-22. PMID: 21458486; PMCID: PMC3109129.
  26. Burpee T, Mitchell P, Fishman D, Islam S, Nemeth E, Westerman M, Wessling-Resnick M, Grand RJ. Intestinal ferroportin expression in pediatric Crohn's disease. Inflamm Bowel Dis. 2011 Feb; 17(2):524-31. PMID: 20564534; PMCID: PMC3733087.
  27. Kim J, Molina RM, Donaghey TC, Buckett PD, Brain JD, Wessling-Resnick M. Influence of DMT1 and iron status on inflammatory responses in the lung. Am J Physiol Lung Cell Mol Physiol. 2011 Apr; 300(4):L659-65. PMID: 21278260; PMCID: PMC3075097.
  28. Johnson EE, Sandgren A, Cherayil BJ, Murray M, Wessling-Resnick M. Role of ferroportin in macrophage-mediated immunity. Infect Immun. 2010 Dec; 78(12):5099-106. PMID: 20837712; PMCID: PMC2981308.
  29. Wessling-Resnick M. Iron homeostasis and the inflammatory response. Annu Rev Nutr. 2010 Aug 21; 30:105-22. PMID: 20420524; PMCID: PMC3108097.
  30. Deb S, Johnson EE, Robalinho-Teixeira RL, Wessling-Resnick M. Modulation of intracellular iron levels by oxidative stress implicates a novel role for iron in signal transduction. Biometals. 2009 Oct; 22(5):855-62. PMID: 19190985; PMCID: PMC2915439.
  31. Buckett PD, Wessling-Resnick M. Small molecule inhibitors of divalent metal transporter-1. Am J Physiol Gastrointest Liver Physiol. 2009 Apr; 296(4):G798-804. PMID: 19179627; PMCID: PMC2670682.
  32. Collins JF, Wessling-Resnick M, Knutson MD. Hepcidin regulation of iron transport. J Nutr. 2008 Nov; 138(11):2284-8. PMID: 18936232; PMCID: PMC2764359.
  33. Wang L, Johnson EE, Shi HN, Walker WA, Wessling-Resnick M, Cherayil BJ. Attenuated inflammatory responses in hemochromatosis reveal a role for iron in the regulation of macrophage cytokine translation. J Immunol. 2008 Aug 15; 181(4):2723-31. PMID: 18684963; PMCID: PMC2561261.
  34. Wessling-Resnick M. The irony of host defense. Blood. 2008 Aug 01; 112(3):460. PMID: 18650460.
    View in: PubMed
  35. Horonchik L, Wessling-Resnick M. The small-molecule iron transport inhibitor ferristatin/NSC306711 promotes degradation of the transferrin receptor. Chem Biol. 2008 Jul 21; 15(7):647-53. PMID: 18635001; PMCID: PMC3747564.
  36. Thompson K, Molina RM, Donaghey T, Brain JD, Wessling-Resnick M. Iron absorption by Belgrade rat pups during lactation. Am J Physiol Gastrointest Liver Physiol. 2007 Sep; 293(3):G640-4. PMID: 17640977.
    View in: PubMed
  37. Johnson EE, Wessling-Resnick M. Flatiron mice and ferroportin disease. Nutr Rev. 2007 Jul; 65(7):341-5. PMID: 17695375; PMCID: PMC2494882.
  38. Thompson K, Molina RM, Brain JD, Wessling-Resnick M. Belgrade rats display liver iron loading. J Nutr. 2006 Dec; 136(12):3010-4. PMID: 17116712; PMCID: PMC1896271.
  39. Thompson K, Molina RM, Donaghey T, Schwob JE, Brain JD, Wessling-Resnick M. Olfactory uptake of manganese requires DMT1 and is enhanced by anemia. FASEB J. 2007 Jan; 21(1):223-30. PMID: 17116743; PMCID: PMC2432183.
  40. Wetli HA, Buckett PD, Wessling-Resnick M. Small-molecule screening identifies the selanazal drug ebselen as a potent inhibitor of DMT1-mediated iron uptake. Chem Biol. 2006 Sep; 13(9):965-72. PMID: 16984886; PMCID: PMC2542486.
  41. Chlosta S, Fishman DS, Harrington L, Johnson EE, Knutson MD, Wessling-Resnick M, Cherayil BJ. The iron efflux protein ferroportin regulates the intracellular growth of Salmonella enterica. Infect Immun. 2006 May; 74(5):3065-7. PMID: 16622252; PMCID: PMC1459754.
  42. Heilig EA, Thompson KJ, Molina RM, Ivanov AR, Brain JD, Wessling-Resnick M. Manganese and iron transport across pulmonary epithelium. Am J Physiol Lung Cell Mol Physiol. 2006 Jun; 290(6):L1247-59. PMID: 16428268.
    View in: PubMed
  43. Wessling-Resnick M. Iron imports. III. Transfer of iron from the mucosa into circulation. Am J Physiol Gastrointest Liver Physiol. 2006 Jan; 290(1):G1-6. PMID: 16354771; PMCID: PMC2494859.
  44. Brain JD, Heilig E, Donaghey TC, Knutson MD, Wessling-Resnick M, Molina RM. Effects of iron status on transpulmonary transport and tissue distribution of Mn and Fe. Am J Respir Cell Mol Biol. 2006 Mar; 34(3):330-7. PMID: 16340001; PMCID: PMC2644198.
  45. Yin J, Lin AJ, Buckett PD, Wessling-Resnick M, Golan DE, Walsh CT. Single-cell FRET imaging of transferrin receptor trafficking dynamics by Sfp-catalyzed, site-specific protein labeling. Chem Biol. 2005 Sep; 12(9):999-1006. PMID: 16183024; PMCID: PMC2494879.
  46. Bergqvist SW, Sandberg AS, Andlid T, Wessling-Resnick M. Lactic acid decreases Fe(II) and Fe(III) retention but increases Fe(III) transepithelial transfer by Caco-2 cells. J Agric Food Chem. 2005 Aug 24; 53(17):6919-23. PMID: 16104821.
    View in: PubMed
  47. Thompson K, Molina R, Donaghey T, Brain JD, Wessling-Resnick M. The influence of high iron diet on rat lung manganese absorption. Toxicol Appl Pharmacol. 2006 Jan 01; 210(1-2):17-23. PMID: 15993455.
    View in: PubMed
  48. Knutson MD, Oukka M, Koss LM, Aydemir F, Wessling-Resnick M. Iron release from macrophages after erythrophagocytosis is up-regulated by ferroportin 1 overexpression and down-regulated by hepcidin. Proc Natl Acad Sci U S A. 2005 Feb 01; 102(5):1324-8. PMID: 15665091; PMCID: PMC547844.
  49. Heilig E, Molina R, Donaghey T, Brain JD, Wessling-Resnick M. Pharmacokinetics of pulmonary manganese absorption: evidence for increased susceptibility to manganese loading in iron-deficient rats. Am J Physiol Lung Cell Mol Physiol. 2005 May; 288(5):L887-93. PMID: 15618452.
    View in: PubMed
  50. Simpson JC, Griffiths G, Wessling-Resnick M, Fransen JA, Bennett H, Jones AT. A role for the small GTPase Rab21 in the early endocytic pathway. J Cell Sci. 2004 Dec 15; 117(Pt 26):6297-311. PMID: 15561770.
    View in: PubMed
  51. Robb A, Wessling-Resnick M. Regulation of transferrin receptor 2 protein levels by transferrin. Blood. 2004 Dec 15; 104(13):4294-9. PMID: 15319276.
    View in: PubMed
  52. Robb AD, Ericsson M, Wessling-Resnick M. Transferrin receptor 2 mediates a biphasic pattern of transferrin uptake associated with ligand delivery to multivesicular bodies. Am J Physiol Cell Physiol. 2004 Dec; 287(6):C1769-75. PMID: 15317665.
    View in: PubMed
  53. Nieland TJ, Feng Y, Brown JX, Chuang TD, Buckett PD, Wang J, Xie XS, McGraw TE, Kirchhausen T, Wessling-Resnick M. Chemical genetic screening identifies sulfonamides that raise organellar pH and interfere with membrane traffic. Traffic. 2004 Jul; 5(7):478-92. PMID: 15180825; PMCID: PMC2494881.
  54. Knutson M, Menzies S, Connor J, Wessling-Resnick M. Developmental, regional, and cellular expression of SFT/UbcH5A and DMT1 mRNA in brain. J Neurosci Res. 2004 Jun 01; 76(5):633-41. PMID: 15139022.
    View in: PubMed
  55. Brown JX, Buckett PD, Wessling-Resnick M. Identification of small molecule inhibitors that distinguish between non-transferrin bound iron uptake and transferrin-mediated iron transport. Chem Biol. 2004 Mar; 11(3):407-16. PMID: 15123270.
    View in: PubMed
  56. Chung J, Prohaska JR, Wessling-Resnick M. Ferroportin-1 is not upregulated in copper-deficient mice. J Nutr. 2004 Mar; 134(3):517-21. PMID: 14988440.
    View in: PubMed
  57. Chung J, Haile DJ, Wessling-Resnick M. Copper-induced ferroportin-1 expression in J774 macrophages is associated with increased iron efflux. Proc Natl Acad Sci U S A. 2004 Mar 02; 101(9):2700-5. PMID: 14973193; PMCID: PMC365684.
  58. Knutson MD, Vafa MR, Haile DJ, Wessling-Resnick M. Iron loading and erythrophagocytosis increase ferroportin 1 (FPN1) expression in J774 macrophages. Blood. 2003 Dec 01; 102(12):4191-7. PMID: 12907459.
    View in: PubMed
  59. Chung J, Wessling-Resnick M. Molecular mechanisms and regulation of iron transport. Crit Rev Clin Lab Sci. 2003 Apr; 40(2):151-82. PMID: 12755454.
    View in: PubMed
  60. Knutson M, Wessling-Resnick M. Iron metabolism in the reticuloendothelial system. Crit Rev Biochem Mol Biol. 2003; 38(1):61-88. PMID: 12641343.
    View in: PubMed
  61. Wessling-Resnick M. A possible link between hepcidin and regulation of dietary iron absorption. Nutr Rev. 2002 Nov; 60(11):371-4. PMID: 12462520.
    View in: PubMed
  62. Wessling-Resnick M. Understanding copper uptake at the molecular level. Nutr Rev. 2002 Jun; 60(6):177-9. PMID: 12078916.
    View in: PubMed
  63. Han O, Wessling-Resnick M. Copper repletion enhances apical iron uptake and transepithelial iron transport by Caco-2 cells. Am J Physiol Gastrointest Liver Physiol. 2002 Mar; 282(3):G527-33. PMID: 11842003.
    View in: PubMed
  64. Aisen P, Enns C, Wessling-Resnick M. Chemistry and biology of eukaryotic iron metabolism. Int J Biochem Cell Biol. 2001 Oct; 33(10):940-59. PMID: 11470229.
    View in: PubMed
  65. Quellhorst GJ, Allen CM, Wessling-Resnick M. Modification of Rab5 with a photoactivatable analog of geranylgeranyl diphosphate. J Biol Chem. 2001 Nov 02; 276(44):40727-33. PMID: 11522782.
    View in: PubMed
  66. Knutson MD, Levy JE, Andrews NC, Wessling-Resnick M. Expression of stimulator of Fe transport is not enhanced in Hfe knockout mice. J Nutr. 2001 May; 131(5):1459-64. PMID: 11340100.
    View in: PubMed
  67. Wessling-Resnick M. Iron transport. Annu Rev Nutr. 2000; 20:129-51. PMID: 10940329.
    View in: PubMed
  68. Jones AT, Spiro DJ, Kirchhausen T, Melançon P, Wessling-Resnick M. Studies on the inhibition of endosome fusion by GTPgammaS-bound ARF. J Cell Sci. 1999 Oct; 112 ( Pt 20):3477-85. PMID: 10504296.
    View in: PubMed
  69. Akompong T, Ramm E, Chang C, Yu ZK, Wessling-Resnick M. Immunological analysis of beta-thalassemic mouse intestinal proteins reveals up-regulation of sucrase-isomaltase in response to iron overload. J Nutr. 1999 May; 129(5):949-52. PMID: 10222384.
    View in: PubMed
  70. Aisen P, Wessling-Resnick M, Leibold EA. Iron metabolism. Curr Opin Chem Biol. 1999 Apr; 3(2):200-6. PMID: 10226041.
    View in: PubMed
  71. Wessling-Resnick M. Biochemistry of iron uptake. Crit Rev Biochem Mol Biol. 1999; 34(5):285-314. PMID: 10565676.
    View in: PubMed
  72. Gutierrez JA, Yu J, Wessling-Resnick M. Characterization and chromosomal mapping of the human gene for SFT, a stimulator of Fe transport. Biochem Biophys Res Commun. 1998 Dec 30; 253(3):739-42. PMID: 9918797.
    View in: PubMed
  73. Yu J, Yu ZK, Wessling-Resnick M. Expression of SFT (stimulator of Fe transport) is enhanced by iron chelation in HeLa cells and by hemochromatosis in liver. J Biol Chem. 1998 Dec 25; 273(52):34675-8. PMID: 9856986.
    View in: PubMed
  74. Gutierrez JA, Inman RS, Akompong T, Yu J, Wessling-Resnick M. Metabolic depletion inhibits the uptake of nontransferrin-bound iron by K562 cells. J Cell Physiol. 1998 Dec; 177(4):585-92. PMID: 10092211.
    View in: PubMed
  75. Jones AT, Wessling-Resnick M. Inhibition of in vitro endosomal vesicle fusion activity by aminoglycoside antibiotics. J Biol Chem. 1998 Sep 25; 273(39):25301-9. PMID: 9737996.
    View in: PubMed
  76. Yu J, Wessling-Resnick M. Structural and functional analysis of SFT, a stimulator of Fe Transport. J Biol Chem. 1998 Aug 14; 273(33):21380-5. PMID: 9694900.
    View in: PubMed
  77. Pan JY, Wessling-Resnick M. GEF-mediated GDP/GTP exchange by monomeric GTPases: a regulatory role for Mg2+? Bioessays. 1998 Jun; 20(6):516-21. PMID: 9699463.
    View in: PubMed
  78. Yu J, Wessling-Resnick M. Influence of copper depletion on iron uptake mediated by SFT, a stimulator of Fe transport. J Biol Chem. 1998 Mar 20; 273(12):6909-15. PMID: 9506995.
    View in: PubMed
  79. Gutierrez JA, Yu J, Rivera S, Wessling-Resnick M. Functional expression cloning and characterization of SFT, a stimulator of Fe transport. J Cell Biol. 1997 Nov 17; 139(4):895-905. PMID: 9362508; PMCID: PMC2139974.
  80. Green EG, Ramm E, Riley NM, Spiro DJ, Goldenring JR, Wessling-Resnick M. Rab11 is associated with transferrin-containing recycling compartments in K562 cells. Biochem Biophys Res Commun. 1997 Oct 20; 239(2):612-6. PMID: 9344879.
    View in: PubMed
  81. Yanachkov I, Pan JY, Wessling-Resnick M, Wright GE. Synthesis and effect of nonhydrolyzable xanthosine triphosphate derivatives on prenylation of Rab5D136N. Mol Pharmacol. 1997 Jan; 51(1):47-51. PMID: 9016345.
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  82. Barisani D, Wessling-Resnick M. Fe-nitrilotriacetic acid--binding proteins associated with rat liver plasma membranes. Hepatology. 1996 Oct; 24(4):934-8. PMID: 8855201.
    View in: PubMed
  83. Spiro DJ, Boll W, Kirchhausen T, Wessling-Resnick M. Wortmannin alters the transferrin receptor endocytic pathway in vivo and in vitro. Mol Biol Cell. 1996 Mar; 7(3):355-67. PMID: 8868465; PMCID: PMC275889.
  84. Pan JY, Sanford JC, Wessling-Resnick M. Influence of Mg2+ on the structure and function of Rab5. J Biol Chem. 1996 Jan 19; 271(3):1322-8. PMID: 8576119.
    View in: PubMed
  85. Gutierrez JA, Wessling-Resnick M. Molecular mechanisms of iron transport. Crit Rev Eukaryot Gene Expr. 1996; 6(1):1-14. PMID: 8882304.
    View in: PubMed
  86. Sanford JC, Yu J, Pan JY, Wessling-Resnick M. GDP dissociation inhibitor serves as a cytosolic acceptor for newly synthesized and prenylated Rab5. J Biol Chem. 1995 Nov 10; 270(45):26904-9. PMID: 7592935.
    View in: PubMed
  87. Pan JY, Sanford JC, Wessling-Resnick M. Effect of guanine nucleotide binding on the intrinsic tryptophan fluorescence properties of Rab5. J Biol Chem. 1995 Oct 13; 270(41):24204-8. PMID: 7592625.
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  88. Hoffenberg S, Nikolova L, Pan JY, Daniel DS, Wessling-Resnick M, Knoll BJ, Dickey BF. Functional and structural interactions of the Rab5 D136N mutant with xanthine nucleotides. Biochem Biophys Res Commun. 1995 Oct 04; 215(1):241-9. PMID: 7575598.
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  89. Barisani D, Berg CL, Wessling-Resnick M, Gollan JL. Evidence for a low Km transporter for non-transferrin-bound iron in isolated rat hepatocytes. Am J Physiol. 1995 Oct; 269(4 Pt 1):G570-6. PMID: 7485509.
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  90. Akompong T, Inman RS, Wessling-Resnick M. Phorbol esters stimulate non-transferrin iron uptake by K562 cells. J Biol Chem. 1995 Sep 08; 270(36):20937-41. PMID: 7673117.
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  91. Spiro DJ, Taylor TC, Melançon P, Wessling-Resnick M. Cytosolic ADP-ribosylation factors are not required for endosome-endosome fusion but are necessary for GTP gamma S inhibition of fusion. J Biol Chem. 1995 Jun 09; 270(23):13693-7. PMID: 7775422.
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  92. Hoffenberg S, Sanford JC, Liu S, Daniel DS, Tuvin M, Knoll BJ, Wessling-Resnick M, Dickey BF. Biochemical and functional characterization of a recombinant GTPase, Rab5, and two of its mutants. J Biol Chem. 1995 Mar 10; 270(10):5048-56. PMID: 7890612.
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  93. Schonhorn JE, Akompong T, Wessling-Resnick M. Mechanism of transferrin receptor down-regulation in K562 cells in response to protein kinase C activation. J Biol Chem. 1995 Feb 24; 270(8):3698-705. PMID: 7876109.
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  94. Sanford JC, Foster L, Kapadia Z, Wessling-Resnick M. Analysis of the stoichiometry of Rab protein prenylation. Anal Biochem. 1995 Jan 20; 224(2):547-56. PMID: 7733457.
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  95. Sanford JC, Pan Y, Wessling-Resnick M. Properties of Rab5 N-terminal domain dictate prenylation of C-terminal cysteines. Mol Biol Cell. 1995 Jan; 6(1):71-85. PMID: 7749197; PMCID: PMC275815.
  96. Wolf G, Wessling-Resnick M. An integrin-mobilferrin iron transport pathway in intestine and hematopoietic cells. Nutr Rev. 1994 Nov; 52(11):387-9. PMID: 7854652.
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  97. Inman RS, Coughlan MM, Wessling-Resnick M. Extracellular ferrireductase activity of K562 cells is coupled to transferrin-independent iron transport. Biochemistry. 1994 Oct 04; 33(39):11850-7. PMID: 7918403.
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  98. Schonhorn JE, Wessling-Resnick M. Brefeldin A down-regulates the transferrin receptor in K562 cells. Mol Cell Biochem. 1994 Jun 29; 135(2):159-69. PMID: 7838144.
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  99. Sanford JC, Pan Y, Wessling-Resnick M. Prenylation of Rab5 is dependent on guanine nucleotide binding. J Biol Chem. 1993 Nov 15; 268(32):23773-6. PMID: 8226909.
    View in: PubMed
  100. Inman RS, Wessling-Resnick M. Characterization of transferrin-independent iron transport in K562 cells. Unique properties provide evidence for multiple pathways of iron uptake. J Biol Chem. 1993 Apr 25; 268(12):8521-8. PMID: 8473296.
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  101. Wessling-Resnick M, Braell WA. Characterization of the mechanism of endocytic vesicle fusion in vitro. J Biol Chem. 1990 Oct 05; 265(28):16751-9. PMID: 2120206.
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  102. Wessling-Resnick M, Braell WA. The sorting and segregation mechanism of the endocytic pathway is functional in a cell-free system. J Biol Chem. 1990 Jan 15; 265(2):690-9. PMID: 2153110.
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  103. Wessling-Resnick M, Johnson GL. Evidence for oligomeric forms of transducins alpha subunit: formation of intermolecular alpha-alpha disulfide linkages. Biochem Biophys Res Commun. 1989 Mar 15; 159(2):651-7. PMID: 2494995.
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  104. Dhanasekaran N, Wessling-Resnick M, Kelleher DJ, Johnson GL, Ruoho AE. Mapping of the carboxyl terminus within the tertiary structure of transducin's alpha subunit using the heterobifunctional cross-linking reagent, 125I-N-(3-iodo-4-azidophenylpropionamido-S-(2-thiopyridyl) cysteine. J Biol Chem. 1988 Dec 05; 263(34):17942-50. PMID: 3192520.
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  105. Wessling-Resnick M, Johnson GL. Transducin interactions with rhodopsin. Evidence for positive cooperative behavior. J Biol Chem. 1987 Sep 15; 262(26):12444-7. PMID: 3114258.
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  106. Wessling-Resnick M, Johnson GL. Kinetic and hydrodynamic properties of transducin: comparison of physical and structural parameters for GTP-binding regulatory proteins. Biochemistry. 1987 Jul 14; 26(14):4316-23. PMID: 3117101.
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  107. Wessling-Resnick M, Johnson GL. Allosteric behavior in transducin activation mediated by rhodopsin. Initial rate analysis of guanine nucleotide exchange. J Biol Chem. 1987 Mar 15; 262(8):3697-705. PMID: 3102494.
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  108. Aiello LP, Wessling-Resnick M, Pilch PF. Dipeptide metalloendoprotease substrates are glucose transport inhibitors and membrane structure perturbants. Biochemistry. 1986 Jul 01; 25(13):3944-50. PMID: 3527260.
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