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John D. Mitchell, M.D., M.D.

Title
Institution
Department
Address
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Biography
University of Michigan, Ann Arbor, MIBS1996Biomedical Sciences, Cell Biology
University of Michigan Medical School, Ann Arbor, MIMD1999Medicine
Duke University Medical Center, Durham, NC2003Anesthesiology Residency
Duke University Medical Center, Durham, NC2004Cardiothoracic Anesthesiology Fellowship
1992
National Merit Scholarship Finalist
1992 - 1996
United Technologies Corporate Merit Scholarship
1995
Class Honors
2002
FAER Research Scholar- ASA Annual Meeting
2004 - 2005
Rookie of the Year- Department of Anesthesiology
2004
Runner Up- Post Doctorate Clincal Abstract- Department of Anesthesia
2005 - 2006
Teacher of the Year- Department of Anesthesia
2006 - 2007
Teacher of the Year, Department of Anesthesia
2009
Certificate of Merit for Distinctive Service
2010
S. Robert Stone Teaching Award
2010 - 2011
Teacher of the Year- Department of Anesthesia
2015
Larsburg-Johnson Award for Research Innovation
2017
Philip Liu Award for Innovation in Anesthesia Education Research Prize
2019
Distinguished Educator in Anesthesiology

Mentoring
Available: 01/01/19, Expires: 12/31/21

Our group has established and published a variety of techniques to assess proficiency in point of care ultrasound and TEE, but demonstrating transferability from simulator to bedside remains the ultimate goal. Our team studies and quantifies growth of knowledge, technical skills and workflow. Students can be involved in projects to validate existing metrics, develop new metrics, develop and refine multimodal curricula, and design and implement studies to verify learner proficiency with this complex skill set.


Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Ambardekar AP, Walker KK, McKenzie-Brown AM, Brennan K, Jackson C, Edgar L, Ellinas H, Long TR, Trombetta CE, Laskey MG, Wargo BW, Dainer RJ, Draconi CS, Mitchell JD. The Anesthesiology Milestones 2.0: An Improved Competency-Based Assessment for Residency Training. Anesth Analg. 2021 Mar 25. PMID: 33764340.
    Citations:    Fields:    
  2. Martinelli SM, Chen F, Isaak RS, Huffmyer JL, Neves SE, Mitchell JD. Educating Anesthesiologists During the Coronavirus Disease 2019 Pandemic and Beyond. Anesth Analg. 2021 03 01; 132(3):585-593. PMID: 33201006.
    Citations:    Fields:    Translation:HumansPHPublic Health
  3. Neves SE, Chen MJ, Ku CM, Karan S, DiLorenzo AN, Schell RM, Lee DE, Diachun CAB, Jones SB, Mitchell JD. Using Machine Learning to Evaluate Attending Feedback on Resident Performance. Anesth Analg. 2021 02 01; 132(2):545-555. PMID: 33323789.
    Citations:    Fields:    Translation:Humans
  4. Shay D, Ng PY, Dudzinski DM, Grabitz SD, Mitchell JD, Xu X, Houle TT, Bhatt DL, Eikermann M. Preoperative Heart Failure Treatment Prevents Postoperative Cardiac Complications in Patients With Lower Risk: A Retrospective Cohort Study. Ann Surg. 2021 Feb 01. PMID: 33534230.
    Citations:    Fields:    
  5. Kirby GA, Guo W, Mitchell JD, Ma H. Using Lumbar X-Ray to Facilitate Modified Taylor's Approach of Spinal Anesthesia in an Elderly Patient With Scoliosis. Cureus. 2021 Jan 07; 13(1):e12556. PMID: 33564547.
    Citations:    
  6. Ma H, Ruan X, Wong VT, Guo W, Huang Y, Mitchell JD. Identifying the Gap Between Novices and Experts in Fiberoptic Scope Control. J Educ Perioper Med. 2021 Jan-Mar; 23(1):E655. PMID: 33778100.
    Citations:    
  7. Walsh DP, Neves SE, Wong VT, Mitchell JD. Formation of an Intraoperative Educational Curriculum for Anesthesiology Residents Using a Systematic Approach. A A Pract. 2020 Oct; 14(12):e01330. PMID: 33094949.
    Citations:    Fields:    
  8. Brzezinski M, Sawatzki R, Tran HN, Price K, Gregersen M, Wong C, Feng CM, Kimatian S, Mizuguchi KA, Kukreja J, Mitchell JD, Schlecht KD. An Analysis of Successful Features of Anesthesiology Journal Clubs. J Educ Perioper Med. 2020 Oct-Dec; 22(4):E648. PMID: 33447647.
    Citations:    
  9. Walsh DP, Murugappan KR, Oren-Grinberg A, Wong VT, Mitchell JD, Matyal R. Tool to improve qualitative assessment of left ventricular systolic function. Echo Res Pract. 2020 Mar; 7(1):1-8. PMID: 32190341.
    Citations:    
  10. Mitchell JD, Ku C, Lutz B, Shahul S, Wong V, Jones SB. Customizable Curriculum to Enhance Resident Communication Skills. Anesth Analg. 2019 11; 129(5):e155-e158. PMID: 30829671.
    Citations: 1     Fields:    Translation:Humans
  11. Martinelli SM, Isaak RS, Schell RM, Mitchell JD, McEvoy MD, Chen F. Learners and Luddites in the Twenty-first Century: Bringing Evidence-based Education to Anesthesiology. Anesthesiology. 2019 10; 131(4):908-928. PMID: 31365369.
    Citations: 2     Fields:    Translation:Humans
  12. Mahmood E, Khabbaz KR, Bose R, Mitchell J, Zhang Q, Chaudhary O, Mahmood F, Matyal R. Immediate Preoperative Transthoracic Echocardiography for the Prediction of Postoperative Atrial Fibrillation in High-Risk Cardiac Surgery. J Cardiothorac Vasc Anesth. 2020 Mar; 34(3):719-725. PMID: 31635984.
    Citations:    Fields:    
  13. Brzezinski M, Kukreja J, Mitchell JD. Time-efficient, goal-directed, and evidence-based teaching in the ICU. Curr Opin Anaesthesiol. 2019 Apr; 32(2):136-143. PMID: 30817385.
    Citations: 2     Fields:    Translation:Humans
  14. Eosakul ST, Wong V, Ku CM, Mitchell JD. Learning Preferences of First-Year Anesthesiology Residents During Their Orientation Month: A Single-Institution Study. A A Pract. 2019 Feb 01; 12(3):88-92. PMID: 30134254.
    Citations:    Fields:    Translation:Humans
  15. Matyal R, Mitchell JD, Mahmood F, Oren-Grinberg A, Leibowitz A, Amador Y, Wong V, Khamooshian A, Mahmood F, Amir R, Bortman J, Jones SB. Faculty-Focused Perioperative Ultrasound Training Program: A Single-Center Experience. J Cardiothorac Vasc Anesth. 2019 04; 33(4):1037-1043. PMID: 30638919.
    Citations: 1     Fields:    Translation:Humans
  16. Mahmood F, Bortman J, Amir R, Mitchell J, Wong V, Feng R, Gao Z, Amador Y, Montealegre-Gallegos M, Kent T, Matyal R. Training Surgical Residents for Ultrasound-Guided Assessment and Management of Unstable Patients. J Surg Educ. 2019 Mar - Apr; 76(2):540-547. PMID: 30322694.
    Citations: 1     Fields:    Translation:Humans
  17. Matyal R, Mahmood F, Knio ZO, Jones SB, Yeh L, Amir R, Bose R, Mitchell JD. Evaluation of the quality of transesophageal echocardiography images and verification of proficiency Echo Res Pract. 2018 Sep 01; 5(3):89-95. PMID: 30303677.
    Citations: 1     
  18. Mitchell JD, Amir R, Montealegre-Gallegos M, Mahmood F, Shnider M, Mashari A, Yeh L, Bose R, Wong V, Hess P, Amador Y, Jeganathan J, Jones SB, Matyal R. Summative Objective Structured Clinical Examination Assessment at the End of Anesthesia Residency for Perioperative Ultrasound. Anesth Analg. 2018 06; 126(6):2065-2068. PMID: 29381519.
    Citations: 2     Fields:    Translation:Humans
  19. Khan N, Mueller A, Mitchell JD, Bose S. Learning beyond the operating room: a call for feedback on postoperative care. Can J Anaesth. 2018 09; 65(9):1080-1081. PMID: 29744814.
    Citations:    Fields:    Translation:Humans
  20. Matyal R, Mahmood F, Knio ZO, Jones S, Yeh L, Amir R, Bose R, Mitchell JD. Evaluation of the quality of transesophageal echocardiography images and verification of proficiency. Echo Res Pract. 2018 May 09. PMID: 29743181.
    Citations:    
  21. Blum RH, Muret-Wagstaff SL, Boulet JR, Cooper JB, Petrusa ER, Baker KH, Davidyuk G, Dearden JL, Feinstein DM, Jones SB, Kimball WR, Mitchell JD, Nadelberg RL, Wiser SH, Albrecht MA, Anastasi AK, Bose RR, Chang LY, Culley DJ, Fisher LJ, Grover M, Klainer SB, Kveraga R, Martel JP, McKenna SS, Minehart RD, Mitchell JD, Mountjoy JR, Pawlowski JB, Pilon RN, Shook DC, Silver DA, Warfield CA, Zaleski KL. Simulation-based Assessment to Reliably Identify Key Resident Performance Attributes. Anesthesiology. 2018 04; 128(4):821-831. PMID: 29369062.
    Citations: 2     Fields:    Translation:Humans
  22. Gao Z, Bortman J, Mahmood F, Mitchell J, Mahmood F, Matyal R. Vendor-Neutral Right Ventricular Strain Measurement. J Cardiothorac Vasc Anesth. 2018 08; 32(4):1759-1767. PMID: 29555385.
    Citations:    Fields:    Translation:Humans
  23. Mahmood F, Mahmood E, Dorfman RG, Mitchell J, Mahmood FU, Jones SB, Matyal R. Augmented Reality and Ultrasound Education: Initial Experience. J Cardiothorac Vasc Anesth. 2018 06; 32(3):1363-1367. PMID: 29452879.
    Citations: 5     Fields:    Translation:Humans
  24. Al Ghofaily L, Mitchell JD, Woodworth G. Anesthesia Residency Training in Cardiac Anesthesia: Development of a Model Curricula and Educational Resources: The Anesthesia Toolbox. J Cardiothorac Vasc Anesth. 2018 04; 32(2):621-630. PMID: 29306616.
    Citations:    Fields:    Translation:Humans
  25. Mitchell JD, Ku C, Diachun CAB, DiLorenzo A, Lee DE, Karan S, Wong V, Schell RM, Brzezinski M, Jones SB. Enhancing Feedback on Professionalism and Communication Skills in Anesthesia Residency Programs. Anesth Analg. 2017 08; 125(2):620-631. PMID: 28598926.
    Citations: 2     Fields:    Translation:Humans
  26. Martinelli SM, Chen F, DiLorenzo AN, Mayer DC, Fairbanks S, Moran K, Ku C, Mitchell JD, Bowe EA, Royal KD, Hendrickse A, VanDyke K, Trawicki MC, Rankin D, Guldan GJ, Hand W, Gallagher C, Jacob Z, Zvara DA, McEvoy MD, Schell RM. Results of a Flipped Classroom Teaching Approach in Anesthesiology Residents. J Grad Med Educ. 2017 Aug; 9(4):485-490. PMID: 28824763.
    Citations: 7     Fields:    Translation:Humans
  27. Nachshon A, Mitchell JD, Mueller A, Banner-Goodspeed VM, McSparron JI. Expert Evaluation of a Chicken Tissue-based Model for Teaching Ultrasound-guided Central Venous Catheter Insertion. J Educ Perioper Med. 2017 Jan-Mar; 19(1):E503. PMID: 28377943.
    Citations: 1     
  28. Amir R, Knio ZO, Mahmood F, Oren-Grinberg A, Leibowitz A, Bose R, Shaefi S, Mitchell JD, Ahmed M, Bardia A, Talmor D, Matyal R. Ultrasound as a Screening Tool for Central Venous Catheter Positioning and Exclusion of Pneumothorax. Crit Care Med. 2017 Jul; 45(7):1192-1198. PMID: 28422778.
    Citations: 3     Fields:    Translation:Humans
  29. Yeh L, Montealegre-Gallegos M, Mahmood F, Hess PE, Shnider M, Mitchell JD, Jones SB, Mashari A, Wong V, Matyal R. Assessment of Perioperative Ultrasound Workflow Understanding: A Consensus. J Cardiothorac Vasc Anesth. 2017 Feb; 31(1):197-202. PMID: 27686512.
    Citations:    Fields:    Translation:Humans
  30. Mahmood F, Matyal R, Skubas N, Montealegre-Gallegos M, Swaminathan M, Denault A, Sniecinski R, Mitchell JD, Taylor M, Haskins S, Shahul S, Oren-Grinberg A, Wouters P, Shook D, Reeves ST. Perioperative Ultrasound Training in Anesthesiology: A Call to Action. Anesth Analg. 2016 06; 122(6):1794-804. PMID: 27195630.
    Citations: 17     Fields:    Translation:Humans
  31. Montealegre-Gallegos M, Mahmood F, Kim H, Bergman R, Mitchell JD, Bose R, Hawthorne KM, O'Halloran TD, Wong V, Hess PE, Matyal R. Imaging skills for transthoracic echocardiography in cardiology fellows: The value of motion metrics. Ann Card Anaesth. 2016 Apr-Jun; 19(2):245-50. PMID: 27052064.
    Citations: 4     Fields:    Translation:Humans
  32. Mitchell JD. Clinical Anesthesia Fundamentals. Anesthesiology. 2016 Mar; 124(3):738-9. PMID: 26881401.
    Citations:    
  33. Mitchell JD, Ku C, Wong V, Fisher LJ, Muret-Wagstaff SL, Ott Q, Shahul S, Bose R, Tibbles C, Jones SB. The Impact of a Resident Communication Skills Curriculum on Patients' Experiences of Care. A A Case Rep. 2016 Feb 01; 6(3):65-75. PMID: 26669651.
    Citations: 2     Fields:    Translation:Humans
  34. Mitchell JD, Jones SB. Faculty Development in Feedback Provision. Int Anesthesiol Clin. 2016; 54(3):54-65. PMID: 27285072.
    Citations: 1     Fields:    Translation:Humans
  35. Mitchell JD, Montealegre-Gallegos M, Mahmood F, Owais K, Wong V, Ferla B, Chowdhury S, Nachshon A, Doshi R, Matyal R. Multimodal Perioperative Ultrasound Course for Interns Allows for Enhanced Acquisition and Retention of Skills and Knowledge. A A Case Rep. 2015 Oct 01; 5(7):119-23. PMID: 26402024.
    Citations: 2     Fields:    Translation:Humans
  36. Matyal R, Montealegre-Gallegos M, Mitchell JD, Kim H, Bergman R, Hawthorne KM, O'Halloran D, Wong V, Hess PE, Mahmood F. Manual Skill Acquisition During Transesophageal Echocardiography Simulator Training of Cardiology Fellows: A Kinematic Assessment. J Cardiothorac Vasc Anesth. 2015 Dec; 29(6):1504-10. PMID: 26341879.
    Citations: 3     Fields:    Translation:Humans
  37. Mitchell JD, Mahmood F, Wong V, Bose R, Nicolai DA, Wang A, Hess PE, Matyal R. Teaching concepts of transesophageal echocardiography via Web-based modules. J Cardiothorac Vasc Anesth. 2015 Apr; 29(2):402-9. PMID: 25440653.
    Citations: 2     Fields:    Translation:Humans
  38. Owais K, Mitchell JD. Con: Simulation training in transesophageal echocardiography. J Cardiothorac Vasc Anesth. 2014 Oct; 28(5):1412-3. PMID: 25281052.
    Citations:    Fields:    Translation:Humans
  39. Matyal R, Mitchell JD, Hess PE, Chaudary B, Bose R, Jainandunsing JS, Wong V, Mahmood F. Simulator-based transesophageal echocardiographic training with motion analysis: a curriculum-based approach. Anesthesiology. 2014 Aug; 121(2):389-99. PMID: 24667829.
    Citations: 8     Fields:    Translation:Humans
  40. Vinson AE, Mitchell JD. Assessing levels of support for residents following adverse outcomes: a national survey of anesthesia residency programs in the United States. Med Teach. 2014 Oct; 36(10):858-66. PMID: 24804917.
    Citations: 2     Fields:    Translation:Humans
  41. Mitchell JD, Mahmood F, Bose R, Hess PE, Wong V, Matyal R. Novel, multimodal approach for basic transesophageal echocardiographic teaching. J Cardiothorac Vasc Anesth. 2014 Jun; 28(3):800-9. PMID: 24746594.
    Citations:    Fields:    Translation:Humans
  42. Mitchell JD, Holak EJ, Tran HN, Muret-Wagstaff S, Jones SB, Brzezinski M. Are we closing the gap in faculty development needs for feedback training? J Clin Anesth. 2013 Nov; 25(7):560-4. PMID: 24008192.
    Citations: 3     Fields:    Translation:Humans
  43. Shakil O, Mahmood B, Matyal R, Jainandunsing JS, Mitchell J, Mahmood F. Simulation training in echocardiography: the evolution of metrics. J Cardiothorac Vasc Anesth. 2013 Oct; 27(5):1034-40. PMID: 23623888.
    Citations: 2     Fields:    Translation:HumansAnimals
  44. Shahul S, Rhee J, Hacker MR, Gulati G, Mitchell JD, Hess P, Mahmood F, Arany Z, Rana S, Talmor D. Subclinical left ventricular dysfunction in preeclamptic women with preserved left ventricular ejection fraction: a 2D speckle-tracking imaging study. Circ Cardiovasc Imaging. 2012 Nov; 5(6):734-9. PMID: 22891044.
    Citations: 23     Fields:    Translation:Humans
  45. Shahul S, Rhee J, Rana S, Hacker M, Mitchell J, Hess P, Mahmood FU, Talmor D. OS094. Subclinical left ventricular dysfunction in preeclamptic women with preserved left ventricular ejection fraction: A 2D speckle tracking imaging study. Pregnancy Hypertens. 2012 Jul; 2(3):229-30. PMID: 26105308.
    Citations:    Fields:    
  46. Patten IS, Rana S, Shahul S, Rowe GC, Jang C, Liu L, Hacker MR, Rhee JS, Mitchell J, Mahmood F, Hess P, Farrell C, Koulisis N, Khankin EV, Burke SD, Tudorache I, Bauersachs J, del Monte F, Hilfiker-Kleiner D, Karumanchi SA, Arany Z. Cardiac angiogenic imbalance leads to peripartum cardiomyopathy. Nature. 2012 May 09; 485(7398):333-8. PMID: 22596155.
    Citations: 137     Fields:    Translation:HumansAnimalsCells
  47. Warraich H, Matyal R, Shahul S, Mitchell J, Panzica P, Khabbaz K, Mahmood F. Giant saphenous vein graft pseudoaneurysm causing tricuspid valve stenosis. J Card Surg. 2011 Mar; 26(2):177-80. PMID: 21332791.
    Citations: 1     Fields:    Translation:Humans
  48. Brzezinski M, Kukreja J, Mitchell JD, Pagel PS, Tassone RF. Sudden onset of atrial flutter during continuous venovenous hemodialysis. J Cardiothorac Vasc Anesth. 2012 Jun; 26(3):535-6. PMID: 21232978.
    Citations:    Fields:    Translation:Humans
  49. Bose RR, Matyal R, Warraich HJ, Summers J, Subramaniam B, Mitchell J, Panzica PJ, Shahul S, Mahmood F. Utility of a transesophageal echocardiographic simulator as a teaching tool. J Cardiothorac Vasc Anesth. 2011 Apr; 25(2):212-5. PMID: 20974542.
    Citations: 11     Fields:    Translation:Humans
  50. Matyal R, Mahmood F, Hess P, Zhao X, Mitchell J, Maslow A, Gangadharan S, Decamp M. Right ventricular echocardiographic predictors of postoperative supraventricular arrhythmias after thoracic surgery: a pilot study. Ann Thorac Surg. 2010 Oct; 90(4):1080-6. PMID: 20868791.
    Citations: 6     Fields:    Translation:HumansCTClinical Trials
  51. Mitchell JD, Subramaniam B. Pulse plethysmography derived noninvasive measures of volume replacement. Int Anesthesiol Clin. 2010; 48(1):101-14. PMID: 20065729.
    Citations:    Fields:    Translation:Humans
  52. Matyal R, Hess PE, Subramaniam B, Mitchell J, Panzica PJ, Pomposelli F, Mahmood F. Perioperative diastolic dysfunction during vascular surgery and its association with postoperative outcome. J Vasc Surg. 2009 Jul; 50(1):70-6. PMID: 19563954.
    Citations: 20     Fields:    Translation:Humans
  53. Subramaniam B, Panzica PJ, Novack V, Mahmood F, Matyal R, Mitchell JD, Sundar E, Bose R, Pomposelli F, Kersten JR, Talmor DS. Continuous perioperative insulin infusion decreases major cardiovascular events in patients undergoing vascular surgery: a prospective, randomized trial. Anesthesiology. 2009 May; 110(5):970-7. PMID: 19387173.
    Citations: 19     Fields:    Translation:Humans
  54. Bose R, Matyal R, Panzica P, Karthik S, Subramaniam B, Pawlowski J, Mitchell J, Mahmood F. Transesophageal echocardiography simulator: a new learning tool. J Cardiothorac Vasc Anesth. 2009 Aug; 23(4):544-8. PMID: 19303326.
    Citations: 8     Fields:    Translation:Humans
  55. Mahmood F, Matyal R, Maslow A, Subramaniam B, Mitchell J, Panzica P, Karthik S, Hess P. Myocardial performance index is a predictor of outcome after abdominal aortic aneurysm repair. J Cardiothorac Vasc Anesth. 2008 Oct; 22(5):706-12. PMID: 18922427.
    Citations:    Fields:    Translation:Humans
  56. Martinelli SM, Mitchell JD, McCann RL, Podgoreanu MV, Mathew JP, Swaminathan M. Intraoperative transesophageal echocardiography diagnosis of residual tumor fragment after surgical removal of renal cell carcinoma. Anesth Analg. 2008 Jun; 106(6):1633-5. PMID: 18499590.
    Citations: 4     Fields:    Translation:Humans
  57. Mahmood F, Karthik S, Subramaniam B, Panzica PJ, Mitchell J, Lerner AB, Jervis K, Maslow AD. Intraoperative application of geometric three-dimensional mitral valve assessment package: a feasibility study. J Cardiothorac Vasc Anesth. 2008 Apr; 22(2):292-8. PMID: 18375338.
    Citations: 10     Fields:    Translation:Humans
  58. Mitchell JD, Grocott HP, Phillips-Bute B, Mathew JP, Newman MF, Bar-Yosef S. Cytokine secretion after cardiac surgery and its relationship to postoperative fever. Cytokine. 2007 Apr; 38(1):37-42. PMID: 17572096.
    Citations: 10     Fields:    Translation:Humans
  59. Mahmood F, Matyal R, Subramaniam B, Mitchell J, Pomposelli F, Lerner AB, Maslow A, Hess PM. Transmitral flow propagation velocity and assessment of diastolic function during abdominal aortic aneurysm repair. J Cardiothorac Vasc Anesth. 2007 Aug; 21(4):486-91. PMID: 17678772.
    Citations: 3     Fields:    Translation:Humans
  60. Matyal R, Mahmood F, Panzica P, Mitchell J, Lerner A. Response to letter to the editor. Anesthesia and Analgesia. 2007; 104(2):456-457.
  61. Bar-Yosef S, Mitchell JD, Mathew JP, Grocott HP. Inflammatory Response to Cardiopulmonary Bypass and the Risk of Atrial Fibrillation. Anesthesiology. 2006; 105:A609.
  62. Mahmood F, Subramaniam B, Matyal R, Mitchell J. Intraoperative Diastolic Dysfunction and Postoperative Outcome. 2006.
  63. Matyal R, Mahmood F, Panzica P, Mitchell J, Barnett S, Hyde M, Campbell D, Park KW. Inadvertent placement of a flow-directed pulmonary artery catheter in the coronary sinus, detected by transesophageal echocardiography. Anesth Analg. 2006 Feb; 102(2):363-5. PMID: 16428522.
    Citations:    Fields:    Translation:Humans
  64. Mitchell J, Welsby I. Techniques of central venous access [review]. Surgery. 2004; 22(1):1-3.
  65. Mitchell JD, Welsby IJ . Technqiues of arterial access [review]. Surgery. 2004; 22(1):3-4.
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.