Harvard Catalyst Profiles

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Thomas Francis O'Brien, M.D.


The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. R01AI023474 (O'BRIEN, THOMAS FRANCIS) Sep 1, 1985 - Feb 28, 1993
    Role: Principal Investigator

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Stelling J, Read JS, Peters R, Clark A, Bokhari M, O'Brien TF. Staphylococcus aureus antimicrobial susceptibility trends and cluster detection in Vermont: 2012-2018. Expert Rev Anti Infect Ther. 2021 06; 19(6):777-785. PMID: 33131354.
    Citations:    Fields:    Translation:HumansCellsPHPublic Health
  2. Stelling J, Read JS, Fritch W, O'Brien TF, Peters R, Clark A, Bokhari M, Lion M, Katwa P, Kelso P. Surveillance of antimicrobial resistance and evolving microbial populations in Vermont: 2011-2018. Expert Rev Anti Infect Ther. 2020 10; 18(10):1055-1062. PMID: 32552054.
    Citations: 1     Fields:    Translation:HumansCellsPHPublic Health
  3. Baker MA, Yokoe DS, Stelling J, Kleinman K, Kaganov RE, Letourneau AR, Varma N, O'Brien T, Kulldorff M, Babalola D, Barrett C, Drees M, Coady MH, Isaacs A, Platt R, Huang SS. Automated outbreak detection of hospital-associated pathogens: Value to infection prevention programs. Infect Control Hosp Epidemiol. 2020 09; 41(9):1016-1021. PMID: 32519624; PMCID: PMC9451926.
    Citations: 1     Fields:    Translation:HumansPHPublic Health
  4. Lewis RH, Glazer ES, Bittenbinder DM, O'Brien T, Deneve JL, Shibata D, Behrman SW, Vanatta JM, Satapathy SK, Dickson PV. Outcomes Following Resection of Hepatocellular Carcinoma in the Absence of Cirrhosis. J Gastrointest Cancer. 2019 Dec; 50(4):808-815. PMID: 30117090.
    Citations: 3     Fields:    Translation:Humans
  5. O'Brien TF, Clark A, Peters R, Stelling J. Why surveillance of antimicrobial resistance needs to be automated and comprehensive. J Glob Antimicrob Resist. 2019 06; 17:8-15. PMID: 30326273.
    Citations: 8     Fields:    Translation:HumansCells
  6. Tsutsui A, Yahara K, Clark A, Fujimoto K, Kawakami S, Chikumi H, Iguchi M, Yagi T, Baker MA, O'Brien T, Stelling J. Automated detection of outbreaks of antimicrobial-resistant bacteria in Japan. J Hosp Infect. 2019 Jun; 102(2):226-233. PMID: 30321629; PMCID: PMC6461535.
    Citations: 6     Fields:    Translation:HumansPHPublic Health
  7. Weatherall T, Denbo J, Sharpe J, Martin M, O'Brien T, Gupta R, Groshart K, Behrman S, Dickson P. Well-Differentiated, Non-Functional, Non-Ampullary Duodenal Neuroendocrine Tumors: Toward Defining Evaluation and Management. World J Surg. 2017 Mar; 41(3):844-850. PMID: 27743074.
    Citations: 4     Fields:    Translation:Humans
  8. Cerqueira GC, Earl AM, Ernst CM, Grad YH, Dekker JP, Feldgarden M, Chapman SB, Reis-Cunha JL, Shea TP, Young S, Zeng Q, Delaney ML, Kim D, Peterson EM, O'Brien TF, Ferraro MJ, Hooper DC, Huang SS, Kirby JE, Onderdonk AB, Birren BW, Hung DT, Cosimi LA, Wortman JR, Murphy CI, Hanage WP. Multi-institute analysis of carbapenem resistance reveals remarkable diversity, unexplained mechanisms, and limited clonal outbreaks. Proc Natl Acad Sci U S A. 2017 01 31; 114(5):1135-1140. PMID: 28096418; PMCID: PMC5293017.
    Citations: 68     Fields:    Translation:HumansCellsPHPublic Health
  9. Park R, O'Brien TF, Huang SS, Baker MA, Yokoe DS, Kulldorff M, Barrett C, Swift J, Stelling J. Statistical detection of geographic clusters of resistant Escherichia coli in a regional network with WHONET and SaTScan. Expert Rev Anti Infect Ther. 2016 11; 14(11):1097-1107. PMID: 27530311; PMCID: PMC5109973.
    Citations: 2     Fields:    Translation:HumansCellsPHPublic Health
  10. Pillappa R, O'Brien TF, Sullivan JL, Weksler B. Esophageal Actinomycoses Mimicking Malignancy. Ann Thorac Surg. 2016 May; 101(5):1967-70. PMID: 27106429.
    Citations: 4     Fields:    Translation:Humans
  11. Chang HH, Cohen T, Grad YH, Hanage WP, O'Brien TF, Lipsitch M. Origin and proliferation of multiple-drug resistance in bacterial pathogens. Microbiol Mol Biol Rev. 2015 Mar; 79(1):101-16. PMID: 25652543; PMCID: PMC4402963.
    Citations: 74     Fields:    Translation:HumansCells
  12. O'Brien TF, Stelling J. The world's microbiology laboratories can be a global microbial sensor network. Biomedica. 2014 Apr; 34 Suppl 1:9-15. PMID: 24968031.
    Citations: 6     Fields:    Translation:HumansCells
  13. Siedner MJ, Galar A, Guzmán-Suarez BB, Kubiak DW, Baghdady N, Ferraro MJ, Hooper DC, O'Brien TF, Marty FM. Cefepime vs other antibacterial agents for the treatment of Enterobacter species bacteremia. Clin Infect Dis. 2014 Jun; 58(11):1554-63. PMID: 24647022.
    Citations: 29     Fields:    Translation:HumansCells
  14. Galar A, Kulldorff M, Rudnick W, O'Brien TF, Stelling J. Biochemical phenotypes to discriminate microbial subpopulations and improve outbreak detection. PLoS One. 2013; 8(12):e84313. PMID: 24391936.
    Citations:    Fields:    Translation:HumansCellsPHPublic Health
  15. Pan H, O'Brien TF, Wright G, Yang J, Shin J, Wright KL, Zhong XP. Critical role of the tumor suppressor tuberous sclerosis complex 1 in dendritic cell activation of CD4 T cells by promoting MHC class II expression via IRF4 and CIITA. J Immunol. 2013 Jul 15; 191(2):699-707. PMID: 23776173; PMCID: PMC3702379.
    Citations: 31     Fields:    Translation:AnimalsCells
  16. Ditta LC, Qayyum S, O'Brien TF, Choudhri AF, Wilson MW. Chondromyxoid fibroma of the orbit. Ophthalmic Plast Reconstr Surg. 2012 Sep-Oct; 28(5):e105-6. PMID: 22743695.
    Citations: 6     Fields:    Translation:Humans
  17. Osarogiagbon RU, Miller LE, Ramirez RA, Wang CG, O'Brien TF, Yu X, Khandekar A, Schoettle GP, Robbins SG, Robbins ET, Gibson JB. Use of a surgical specimen-collection kit to improve mediastinal lymph-node examination of resectable lung cancer. J Thorac Oncol. 2012 Aug; 7(8):1276-82. PMID: 22653076.
    Citations: 20     Fields:    Translation:Humans
  18. Ramirez RA, Wang CG, Miller LE, Adair CA, Berry A, Yu X, O'Brien TF, Osarogiagbon RU. Incomplete intrapulmonary lymph node retrieval after routine pathologic examination of resected lung cancer. J Clin Oncol. 2012 Aug 10; 30(23):2823-8. PMID: 22778318.
    Citations: 49     Fields:    Translation:Humans
  19. Hooper DC, DeMaria A, Limbago BM, O'Brien TF, McCaughey B. Antibiotic resistance: how serious is the problem, and what can be done? Clin Chem. 2012 Aug; 58(8):1182-6. PMID: 22634378.
    Citations: 7     Fields:    Translation:HumansAnimalsCellsPHPublic Health
  20. O'Brien TF, Zhong XP. The role and regulation of mTOR in T-lymphocyte function. Arch Immunol Ther Exp (Warsz). 2012 Jun; 60(3):173-81. PMID: 22484804; PMCID: PMC3376380.
    Citations: 14     Fields:    Translation:HumansAnimalsCells
  21. Pan H, O'Brien TF, Zhang P, Zhong XP. The role of tuberous sclerosis complex 1 in regulating innate immunity. J Immunol. 2012 Apr 15; 188(8):3658-66. PMID: 22412198; PMCID: PMC3324625.
    Citations: 46     Fields:    Translation:HumansAnimalsCells
  22. Shin J, O'Brien TF, Grayson JM, Zhong XP. Differential regulation of primary and memory CD8 T cell immune responses by diacylglycerol kinases. J Immunol. 2012 Mar 01; 188(5):2111-7. PMID: 22271650; PMCID: PMC3288785.
    Citations: 27     Fields:    Translation:AnimalsCells
  23. O'Brien TF, Gorentla BK, Xie D, Srivatsan S, McLeod IX, He YW, Zhong XP. Regulation of T-cell survival and mitochondrial homeostasis by TSC1. Eur J Immunol. 2011 Nov; 41(11):3361-70. PMID: 21805467; PMCID: PMC3241742.
    Citations: 55     Fields:    Translation:AnimalsCells
  24. O'Brien TF. What has kept the antibiotic miracle alive? N Engl J Med. 2011 Sep 08; 365(10):953-5. PMID: 21899456.
    Citations: 5     Fields:    Translation:HumansCells
  25. Osarogiagbon RU, Allen JW, Farooq A, Berry A, O'Brien T. Pathologic lymph node staging practice and stage-predicted survival after resection of lung cancer. Ann Thorac Surg. 2011 May; 91(5):1486-92. PMID: 21524460.
    Citations: 19     Fields:    Translation:Humans
  26. O'Brien TF, Stelling J. Integrated Multilevel Surveillance of the World's Infecting Microbes and Their Resistance to Antimicrobial Agents. Clin Microbiol Rev. 2011 Apr; 24(2):281-95. PMID: 21482726.
    Citations: 38     Fields:    Translation:HumansPHPublic Health
  27. Weerasuriya K, Stelling J, O'Brien TF. Containing antimicrobial resistance: a renewed effort. Bull World Health Organ. 2010 Dec 01; 88(12):878. PMID: 21124706.
    Citations: 5     Fields:    Translation:Humans
  28. Allen JW, Farooq A, O'Brien TF, Osarogiagbon RU. Quality of surgical resection for nonsmall cell lung cancer in a US metropolitan area. Cancer. 2011 Jan 01; 117(1):134-42. PMID: 20737568.
    Citations: 25     Fields:    Translation:Humans
  29. Huang SS, Yokoe DS, Stelling J, Placzek H, Kulldorff M, Kleinman K, O'Brien TF, Calderwood MS, Vostok J, Dunn J, Platt R. Automated detection of infectious disease outbreaks in hospitals: a retrospective cohort study. PLoS Med. 2010 Feb 23; 7(2):e1000238. PMID: 20186274.
    Citations: 36     Fields:    Translation:HumansPHPublic Health
  30. Osarogiagbon RU, Allen JW, Farooq A, Berry A, Spencer D, O'Brien T. Outcome of surgical resection for pathologic N0 and Nx non-small cell lung cancer. J Thorac Oncol. 2010 Feb; 5(2):191-6. PMID: 20035237.
    Citations: 18     Fields:    Translation:Humans
  31. Delker DA, Geter DR, Roop BC, Ward WO, Ahlborn GJ, Allen JW, Nelson GM, Ouyang M, Welsh W, Chen Y, O'Brien T, Kitchin KT. Oncogene expression profiles in K6/ODC mouse skin and papillomas following a chronic exposure to monomethylarsonous acid. J Biochem Mol Toxicol. 2009 Nov-Dec; 23(6):406-18. PMID: 20024957.
    Citations: 6     Fields:    Translation:Animals
  32. Stelling J, Yih WK, Galas M, Kulldorff M, Pichel M, Terragno R, Tuduri E, Espetxe S, Binsztein N, O'Brien TF, Platt R. Automated use of WHONET and SaTScan to detect outbreaks of Shigella spp. using antimicrobial resistance phenotypes. Epidemiol Infect. 2010 Jun; 138(6):873-83. PMID: 19796449.
    Citations: 27     Fields:    Translation:HumansCellsPHPublic Health
  33. Brennan D, Hu Y, Joubeh S, Choi YW, Whitaker-Menezes D, O'Brien T, Uitto J, Rodeck U, Mahoney MG. Suprabasal Dsg2 expression in transgenic mouse skin confers a hyperproliferative and apoptosis-resistant phenotype to keratinocytes. J Cell Sci. 2007 Mar 01; 120(Pt 5):758-71. PMID: 17284515.
    Citations: 69     Fields:    Translation:AnimalsCells
  34. Okeke IN, Klugman KP, Bhutta ZA, Duse AG, Jenkins P, O'Brien TF, Pablos-Mendez A, Laxminarayan R. Antimicrobial resistance in developing countries. Part II: strategies for containment. Lancet Infect Dis. 2005 Sep; 5(9):568-80. PMID: 16122680.
    Citations: 79     Fields:    Translation:HumansPHPublic Health
  35. Levy SB, O'Brien TF. Global antimicrobial resistance alerts and implications. Clin Infect Dis. 2005 Aug 15; 41 Suppl 4:S219-20. PMID: 16032554.
    Citations: 16     Fields:    Translation:Humans
  36. Okeke IN, Laxminarayan R, Bhutta ZA, Duse AG, Jenkins P, O'Brien TF, Pablos-Mendez A, Klugman KP. Antimicrobial resistance in developing countries. Part I: recent trends and current status. Lancet Infect Dis. 2005 Aug; 5(8):481-93. PMID: 16048717.
    Citations: 239     Fields:    Translation:HumansPHPublic Health
  37. Stelling JM, Travers K, Jones RN, Turner PJ, O'Brien TF, Levy SB. Integrating Escherichia coli antimicrobial susceptibility data from multiple surveillance programs. Emerg Infect Dis. 2005 Jun; 11(6):873-82. PMID: 15963282; PMCID: PMC3367601.
    Citations: 17     Fields:    Translation:HumansCellsPHPublic Health
  38. Brown SM, Benneyan JC, Theobald DA, Sands K, Hahn MT, Potter-Bynoe GA, Stelling JM, O'Brien TF, Goldmann DA. Binary cumulative sums and moving averages in nosocomial infection cluster detection. Emerg Infect Dis. 2002 Dec; 8(12):1426-32. PMID: 12498659; PMCID: PMC2737829.
    Citations: 7     Fields:    Translation:HumansCellsPHPublic Health
  39. Wang F, O'Brien T, Dowling T, Bicker G, Wyvratt J. Unusual effect of column temperature on chromatographic enantioseparation of dihydropyrimidinone acid and methyl ester on amylose chiral stationary phase. J Chromatogr A. 2002 Jun 07; 958(1-2):69-77. PMID: 12134832.
    Citations: 1     Fields:    
  40. O'Brien TF. Emergence, spread, and environmental effect of antimicrobial resistance: how use of an antimicrobial anywhere can increase resistance to any antimicrobial anywhere else. Clin Infect Dis. 2002 Jun 01; 34 Suppl 3:S78-84. PMID: 11988877.
    Citations: 65     Fields:    Translation:HumansAnimalsCells
  41. O'Brien TF, Eskildsen MA, Stelling JM. Using internet discussion of antimicrobial susceptibility databases for continuous quality improvement of the testing and management of antimicrobial resistance. Clin Infect Dis. 2001 Sep 15; 33 Suppl 3:S118-23. PMID: 11524707.
    Citations: 3     Fields:    Translation:HumansPHPublic Health
  42. Tenover FC, Mohammed MJ, Stelling J, O'Brien T, Williams R. Ability of laboratories to detect emerging antimicrobial resistance: proficiency testing and quality control results from the World Health Organization's external quality assurance system for antimicrobial susceptibility testing. J Clin Microbiol. 2001 Jan; 39(1):241-50. PMID: 11136778; PMCID: PMC87709.
    Citations: 29     Fields:    Translation:HumansCells
  43. O'Brien TF, Eskildsen MA, Stelling JM. The complex processes of antimicrobial resistance and the information needed to manage them. Mil Med. 2000 Jul; 165(7 Suppl 2):12-5. PMID: 10920630.
    Citations: 1     Fields:    Translation:HumansPHPublic Health
  44. Teschan PE, Baxter CR, O'Brien TF, Freyhof JN, Hall WH. Prophylactic hemodialysis in the treatment of acute renal failure. Annals of Internal Medicine, 53:992-1016, 1960. J Am Soc Nephrol. 1998 Dec; 9(12):2384-97. PMID: 9848796.
    Citations: 2     Fields:    Translation:HumansAnimals
  45. Kay BA, Timperi RJ, Morse SS, Forslund D, McGowan JJ, O'Brien T. Innovative information-sharing strategies. Emerg Infect Dis. 1998 Jul-Sep; 4(3):465-6. PMID: 9716975; PMCID: PMC2640296.
    Citations: 1     Fields:    Translation:HumansPHPublic Health
  46. O'Brien TF. The global epidemic nature of antimicrobial resistance and the need to monitor and manage it locally. Clin Infect Dis. 1997 Jan; 24 Suppl 1:S2-8. PMID: 8994775.
    Citations: 25     Fields:    Translation:HumansCellsPHPublic Health
  47. Stelling JM, O'Brien TF. Surveillance of antimicrobial resistance: the WHONET program. Clin Infect Dis. 1997 Jan; 24 Suppl 1:S157-68. PMID: 8994799.
    Citations: 40     Fields:    Translation:HumansCellsPHPublic Health
  48. O'Brien TF, Stelling JM. WHONET: removing obstacles to the full use of information about antimicrobial resistance. Diagn Microbiol Infect Dis. 1996 Aug; 25(4):162-8. PMID: 8937840.
    Citations: 12     Fields:    Translation:Humans
  49. O'Brien TF, Stelling JM. WHONET: an information system for monitoring antimicrobial resistance. Emerg Infect Dis. 1995 Apr-Jun; 1(2):66. PMID: 8903165; PMCID: PMC2626837.
    Citations: 30     Fields:    Translation:HumansPHPublic Health
  50. Sahm DF, O'Brien TF. Detection and surveillance of antimicrobial resistance. Trends Microbiol. 1994 Oct; 2(10):366-71. PMID: 7850203.
    Citations: 3     Fields:    Translation:PHPublic Health
  51. O'Brien TF, DiGiorgio J, Parsonnet KC, Kass EH, Hopkins JD. Plasmid diversity in Escherichia coli isolated from processed poultry and poultry processors. Vet Microbiol. 1993 Jun; 35(3-4):243-55. PMID: 8105602.
    Citations: 1     Fields:    Translation:HumansAnimalsCellsPHPublic Health
  52. Acar JF, O'Brien TF, Goldstein FW, Jones RN. The epidemiology of bacterial resistance to quinolones. Drugs. 1993; 45 Suppl 3:24-8. PMID: 7689447.
    Citations: 8     Fields:    Translation:HumansCells
  53. Neu HC, Duma RJ, Jones RN, McGowan JE, O'Brien TF, Sabath LD, Sanders CC, Schaffner W, Tally FP, Tenover FC, et al. Antibiotic resistance. Epidemiology and therapeutics. Diagn Microbiol Infect Dis. 1992 Feb; 15(2 Suppl):53S-60S. PMID: 1737445.
    Citations: 3     Fields:    Translation:Humans
  54. Neu HC, Duma RJ, Jones RN, McGowan JE, O'Brien TF, Sabath LD, Sanders CC, Schaffner W, Tenover FC, Young LS. Therapeutic and epidemiologic recommendations to reduce the spread of type-I beta-lactamase resistance. Diagn Microbiol Infect Dis. 1992 Feb; 15(2 Suppl):49S-52S. PMID: 1737444.
    Citations: 2     Fields:    
  55. O'Brien TF. Global surveillance of antibiotic resistance. N Engl J Med. 1992 Jan 30; 326(5):339-40. PMID: 1728739.
    Citations: 11     Fields:    Translation:HumansCells
  56. Hopkins JD, Flores A, del Pilar Pla M, Lester S, O'Brien TF. Nosocomial spread of an amikacin resistance gene on both a mobilized, nonconjugative plasmid and a conjugative plasmid. Antimicrob Agents Chemother. 1991 Aug; 35(8):1605-11. PMID: 1656868.
    Citations: 5     Fields:    Translation:HumansCells
  57. Lester SC, del Pilar Pla M, Wang F, Perez Schael I, Jiang H, O'Brien TF. The carriage of Escherichia coli resistant to antimicrobial agents by healthy children in Boston, in Caracas, Venezuela, and in Qin Pu, China. N Engl J Med. 1990 Aug 02; 323(5):285-9. PMID: 2195344.
    Citations: 45     Fields:    Translation:HumansCells
  58. Jacoby GA, Medeiros AA, O'Brien TF, Pinto ME, Jiang H. Broad-spectrum, transmissible beta-lactamases. N Engl J Med. 1988 Sep 15; 319(11):723-4. PMID: 3261838.
    Citations: 27     Fields:    Translation:Cells
  59. Hopkins JD, O'Brien TF, Syvanen M. Functional and structural map of pLST1000: a multiresistance plasmid widely distributed in Enterobacteriaceae. Plasmid. 1988 Sep; 20(2):163-6. PMID: 3237863.
    Citations: 4     Fields:    Translation:Cells
  60. Medeiros AA, O'Brien TF, Rosenberg EY, Nikaido H. Loss of OmpC porin in a strain of Salmonella typhimurium causes increased resistance to cephalosporins during therapy. J Infect Dis. 1987 Nov; 156(5):751-7. PMID: 2821125.
    Citations: 26     Fields:    Translation:HumansCells
  61. O'Brien TF. Resistance of bacteria to antibacterial agents: report of Task Force 2. Rev Infect Dis. 1987 May-Jun; 9 Suppl 3:S244-60. PMID: 3299646.
    Citations: 22     Fields:    Translation:HumansCells
  62. O'Brien TF. Resistance to antibiotics at medical centres in different parts of the world. J Antimicrob Chemother. 1986 Oct; 18 Suppl C:243-53. PMID: 3804896.
    Citations: 7     Fields:    Translation:HumansCells
  63. Mayer KH, Hopkins JD, Gilleece ES, Chao L, O'Brien TF. Molecular evolution, species distribution, and clinical consequences of an endemic aminoglycoside resistance plasmid. Antimicrob Agents Chemother. 1986 Apr; 29(4):628-33. PMID: 3010849.
    Citations: 4     Fields:    Translation:Cells
  64. Hopkins JD, Mayer KH, Gilleece ES, O'Brien TF, Syvanen M. Genetic and physical characterization of IncM plasmid pBWH1 and its variance among natural isolates. J Bacteriol. 1986 Jan; 165(1):47-52. PMID: 3941051; PMCID: PMC214368.
    Citations: 2     Fields:    Translation:Cells
  65. O'Brien TF, Pla MP, Mayer KH, Kishi H, Gilleece E, Syvanen M, Hopkins JD. Intercontinental spread of a new antibiotic resistance gene on an epidemic plasmid. Science. 1985 Oct 04; 230(4721):87-8. PMID: 2994226.
    Citations: 26     Fields:    Translation:HumansCells
  66. Friedman LS, O'Brien TF, Morse LJ, Chang LW, Wacker WE, Ryan DM, Dienstag JL. Revisiting the Holy Cross football team hepatitis outbreak (1969) by serological analysis. JAMA. 1985 Aug 09; 254(6):774-6. PMID: 2989569.
    Citations: 5     Fields:    Translation:HumansCellsPHPublic Health
  67. Mayer KH, Fling ME, Hopkins JD, O'Brien TF. Trimethoprim resistance in multiple genera of Enterobacteriaceae at a U.S. hospital: spread of the type II dihydrofolate reductase gene by a single plasmid. J Infect Dis. 1985 May; 151(5):783-9. PMID: 2985709.
    Citations: 14     Fields:    Translation:HumansCells
  68. O'Brien TF, Mayer KH, Hopkins JD, Farrell JJ, Chao L, Kent RL. Resistance to antibiotics in clinical isolates of Klebsiella pneumoniae. Infect Control. 1985 Feb; 6(2):64-7. PMID: 3882592.
    Citations: 2     Fields:    Translation:HumansCells
  69. Flaherty PJ, Liljestrand JS, O'Brien TF. Urinary tract infections in an American rehabilitation hospital. J Hosp Infect. 1984 Dec; 5 Suppl A:75-80. PMID: 6084690.
    Citations: 1     Fields:    Translation:Humans
  70. Kishi H, Evans D, Hopkins JD, Medeiros AA, O'Brien TF. Diagnostic microbiology laboratory susceptibility test results discriminate distinctive antibiotic resistance plasmids. Diagn Microbiol Infect Dis. 1984 Sep; 2(4):309-16. PMID: 6091987.
    Citations: 1     Fields:    Translation:Cells
  71. Flaherty PJ, Liljestrand JS, O'Brien TF. Infection control surveillance in a rehabilitation hospital. Arch Phys Med Rehabil. 1984 Jun; 65(6):313-5. PMID: 6732458.
    Citations:    Fields:    Translation:Humans
  72. O'Brien TF, Mayer KH, Hopkins JD, Chao L. New concepts in medical bacteriology. J Med. 1983; 14(4):271-80. PMID: 6368718.
    Citations:    Fields:    Translation:HumansCells
  73. O'Brien TF, Hopkins JD, Gilleece ES, Medeiros AA, Kent RL, Blackburn BO, Holmes MB, Reardon JP, Vergeront JM, Schell WL, Christenson E, Bissett ML, Morse EV. Molecular epidemiology of antibiotic resistance in salmonella from animals and human beings in the United States. N Engl J Med. 1982 Jul 01; 307(1):1-6. PMID: 6281645.
    Citations: 34     Fields:    Translation:HumansAnimalsCellsPHPublic Health
  74. O'Brien TF, Acar JF, Altmann G, Blackburn BO, Chao L, Courtieu AL, Evans DA, Guzman M, Holmes M, Jacobs MR, Kent RL, Norton RA, Koornhof HJ, Medeiros AA, Pasculle AW, Surgalla MJ, Williams JD. Laboratory surveillance of synergy between and resistance to trimethoprim and sulfonamides. Rev Infect Dis. 1982 Mar-Apr; 4(2):351-7. PMID: 7111960.
    Citations: 6     Fields:    Translation:HumansCells
  75. Platt R, Ehrlich SL, Afarian J, O'Brien TF, Pennington JE, Kass EH. Moxalactam therapy of infections caused by cephalothin-resistant bacteria: influence of serum inhibitory activity on clinical response and acquisition of antibiotic resistance during therapy. Antimicrob Agents Chemother. 1981 Sep; 20(3):351-5. PMID: 6458233.
    Citations: 25     Fields:    Translation:Humans
  76. Thacker L, McKinney RM, Moss CW, Sommers HM, Spivack ML, O'Brien TF. Thermophilic sporeforming bacilli that mimic fastidious growth characteristics and colonial morphology of legionella. J Clin Microbiol. 1981 Apr; 13(4):794-7. PMID: 7229019.
    Citations: 1     Fields:    Translation:HumansCells
  77. O'Brien TF, Ross DG, Guzman MA, Medeiros AA, Hedges RW, Botstein D. Dissemination of an antibiotic resistance plasmid in hospital patient flora. Antimicrob Agents Chemother. 1980 Apr; 17(4):537-43. PMID: 7396449.
    Citations: 24     Fields:    Translation:HumansCells
  78. Cohen PS, O'Brien TF, Schoenbaum SC, Medeiros AA. The risk of endothelial infection in adults with salmonella bacteremia. Ann Intern Med. 1978 Dec; 89(6):931-2. PMID: 717990.
    Citations: 37     Fields:    Translation:Humans
  79. O'Brien TF, Acar JF, Medeiros AA, Norton RA, Goldstein F, Kent RL. International comparison of prevalence of resistance to antibiotics. JAMA. 1978 Apr 14; 239(15):1518-23. PMID: 633562.
    Citations: 11     Fields:    Translation:HumansCells
  80. O'Brien TF, Norton RA, Kent RL, Medeiros AA. International surveillance of prevalence of antibiotic resistance. J Antimicrob Chemother. 1977 Nov; 3 Suppl C:59-66. PMID: 340447.
    Citations: 4     Fields:    Translation:Cells
  81. Moxon ER, Medeiros AA, O'Brien TF. Beta-lactamase effect on ampicillin treatment of Haemophilus influenzae B bacteremia and meningitis in infant rats. Antimicrob Agents Chemother. 1977 Oct; 12(4):461-4. PMID: 303497.
    Citations: 7     Fields:    Translation:AnimalsCells
  82. Barry AL, Schoenknecht FD, Norton R, O'Brien TF, Matsen JM, Thornsberry C, Thrupp LD, Markley E, Gavan TL. Inter- and intralaboratory variability in antibiotic susceptibility tests with Pseudomonas aeruginosa and Enterobacteriaceae. J Infect Dis. 1976 Oct; 134(4):328-35. PMID: 185302.
    Citations: 3     Fields:    Translation:Cells
  83. Gantz NM, Myerowitz RL, Medeiros AA, Carrera GF, Wilson RE, O'Brien TF. Listeroisis in immunosuppressed patients. A cluster of eight cases. Am J Med. 1975 May; 58(5):637-43. PMID: 805536.
    Citations: 11     Fields:    Translation:HumansCells
  84. Medeiros AA, O'Brien TF. Ampicillin-resistant Haemophilus influenzae type B possessing a TEM-type beta-lactamase but little permeability barrier to ampicillin. Lancet. 1975 Mar 29; 1(7909):716-9. PMID: 47483.
    Citations: 46     Fields:    Translation:Cells
  85. O'Brien TF, Kent RL, Medeiros AA. Computer surveillance of shifts in the gross patient flora during hospitalization. J Infect Dis. 1975 Feb; 131(2):88-96. PMID: 804021.
    Citations: 2     Fields:    Translation:HumansCells
  86. Medeiros AA, Kent RL, O'Brien TF. Characterization and prevalence of the different mechanisms of resistance to beta-lactam antibiotics in clinical isolates of Escherichia coli. Antimicrob Agents Chemother. 1974 Dec; 6(6):791-801. PMID: 4615632.
    Citations: 6     Fields:    Translation:Cells
  87. Gantz NM, Medeiros AA, Swain JL, O'Brien TF. Vacuum blood-culture bottles inhibiting growth of Candida and fostering growth of Bacteroides. Lancet. 1974 Nov 16; 2(7890):1174-6. PMID: 4139592.
    Citations: 17     Fields:    Translation:AnimalsCells
  88. Medeiros AA, O'brien TF. Mechanisms of resistance to cephalosporins in ampicillin-resistant Escherichia coli. J Infect Dis. 1973 Oct; 128:Suppl:S335-4. PMID: 4582843.
    Citations: 4     Fields:    Translation:Cells
  89. Wacker WE, Riordan JF, Snodgrass PJ, Chang LW, Morse LJ, O'Brien TF, Reddy WJ. The Holy Cross hepatitis outbreak: clinical and chemical abnormalities. Arch Intern Med. 1972 Sep; 130(3):357-60. PMID: 5055691.
    Citations: 2     Fields:    Translation:HumansPHPublic Health
  90. Myerowitz RL, Medeiros AA, O'Brien TF. Bacterial infection in renal homotransplant recipients. A study of fifty-three bacteremic episodes. Am J Med. 1972 Sep; 53(3):308-14. PMID: 4559986.
    Citations: 15     Fields:    Translation:Humans
  91. Morse LJ, Bryan JA, Hurley JP, Murphy JF, O'Brien TF, Wacker WE. The Holy Cross college football team hepatitis outbreak. JAMA. 1972 Feb; 219(6):706-8. PMID: 5066695.
    Citations: 10     Fields:    Translation:HumansPHPublic Health
  92. Medeiros AA, O'Brien TF, Wacker WE, Yulug NF. Effect of salt concentration on the apparent in-vitro susceptibility of Pseudomonas and other gram-negative bacilli to gentamicin. J Infect Dis. 1971 Dec; 124 Suppl:S59-64. PMID: 5001630.
    Citations: 47     Fields:    Translation:Cells
  93. Briggs WA, Merrill JP, O'Brien TF, Wilson RE, Birtch AG, Murray JE. Severe pneumonia in renal transplant patients. One year's experience. Ann Intern Med. 1971 Dec; 75(6):887-94. PMID: 4944157.
    Citations: 5     Fields:    Translation:Humans
  94. Myerowitz RL, Medeiros AA, O'Brien TF. Recent experience with bacillemia due to gram-negative organisms. J Infect Dis. 1971 Sep; 124(3):239-46. PMID: 4947185.
    Citations: 24     Fields:    Translation:HumansCells
  95. Axelrod L, Munster AM, O'Brien TF. Typhoid cholecystitis and gallbladder carcinoma after interval of 67 years. JAMA. 1971 Jul 05; 217(1):83. PMID: 5108716.
    Citations: 8     Fields:    Translation:HumansCells
  96. Medeiros AA, O'Brien TF. Replicate inoculation of multi-chambered trays. Lab Pract. 1970 Oct; 19(10):1039. PMID: 4919672.
    Citations:    Fields:    
  97. Chang LW, O'Brien TF. Australia antigen serology in the Holy Cross football team hepatitis outbreak. Lancet. 1970 Jul 11; 1(7663):59-61. PMID: 4193356.
    Citations: 7     Fields:    Translation:HumansCellsPHPublic Health
  98. Morse LJ, Bryan JA, Chang LW, Hurley JP, Murphy JF, O'Brien TF. Holy Cross football team hepatitis outbreak. Antimicrob Agents Chemother (Bethesda). 1970; 10:30-2. PMID: 5521349.
    Citations:    Translation:HumansPHPublic Health
  99. O'Brien TF, Kent RL, Medeiros AA. Computer-generated plots of results of antimicrobial-susceptibility tests. JAMA. 1969 Oct 06; 210(1):84-92. PMID: 4309462.
    Citations: 12     Fields:    Translation:HumansCells
  100. Medeiros AA, O'Brien TF. Contribution of R factors to the antibiotic resistance of hospital isolates of Serratia. Antimicrob Agents Chemother (Bethesda). 1968; 8:30-5. PMID: 4898531.
    Citations: 5     Translation:HumansCells
  101. Medeiros AA, O'Brien TF. R factor-mediated increments in levels of resistance to and enzymatic degradation of penicillins and cephalosporins. Antimicrob Agents Chemother (Bethesda). 1967; 7:271-8. PMID: 4876091.
    Citations: 2     Translation:Cells
  102. Medeiros AA, O'Brien TF. Association of cephalosporinase activity, cephalothin resistance, and episome-mediated drug resistance in Klebsiella strains. Antimicrob Agents Chemother (Bethesda). 1966; 6:321-7. PMID: 5985255.
    Citations: 3     Translation:Cells
  103. O'Brien TF. Diagnostic uses of immunology. Med Clin North Am. 1965 Nov; 49(6):1757-68. PMID: 5319492.
    Citations: 1     Fields:    Translation:Humans
    Citations: 4     Fields:    
    Citations: 11     Fields:    
  106. Thomas F. O'Brien and Albert H.Coons. Studies on Antibody Production VII. The effect of 5-Bromodeoxyuridine on the in vitro anamnestic antibody response. Journal of Experimental Medicine. 1963; 117:1063-1074.
  107. Thomas F. O'Brien, Maria C. Michaelides, and Albert H. Coons. Studies on antibody production VI. The course, sensitivity and histology of the secondary response in vitro. Journal of Experimental Medicine. 1963; 117:1053-1062.
  108. TESCHAN PE, BAXTER CR, O'BRIEN TF, FREYHOF JN, HALL WH. Prophylactic hemodialysis in the treatment of acute renal failure. Ann Intern Med. 1960 Nov; 53:992-1016. PMID: 13776062.
    Citations: 26     Fields:    Translation:HumansCells
  109. TESCHAN PE, O'BRIEN TF, BAXTER CR. Prophylactic daily haemodialysis in acute renal failure. Reduction of morbidity and mortality. U S Armed Forces Med J. 1960 Sep; 11:991-1000. PMID: 13837560.
    Citations:    Translation:Humans
  110. HOLBOROW EJ, BROWN PC, GLYNN LE, HAWES MD, GRESHAM GA, O'BRIEN TF, COOMBS RR. The distribution of the blood group. A antigen in human tissues. Br J Exp Pathol. 1960 Aug; 41:430-7. PMID: 14402554.
    Citations: 27     Fields:    Translation:Humans
  111. DARBY JP, SORENSEN RJ, O'BRIEN TF, TESCHAN PE. Efficient heparin assay for monitoring regional heparinization and hemodialysis. N Engl J Med. 1960 Mar 31; 262:654-7. PMID: 13814070.
    Citations: 2     Fields:    Translation:HumansCells
  112. Teschan PE, Baxter CR, O'Brien TF, Freyhof JN, Hall WH. Comparative evaluation of MacNeill-Collins, twincoil and rotating drum dialyzers, ultrafiltration, chronic vessel cannulation and regional heparinization, with special reference to prophylactic hemodialysis. Transactions of the American Society for Artificial Internal Organs. 1960; 6:76-82.
  113. Teschan PE, Baxter CR, O'Brien TF, Freyhof JN, Hall WH. Comparative evaluation of MacNeill-Collins, twincoil and rotating drum dialyzers ultrafiltration, chronic vessel cannuloation and regional heparinization, with sprcial reference to prophylactic hemodialysis. Transactions of The American Society for Artificial Internal Organs. 1960; 6:76-82.
  114. O'Brien TF, Baxter CR, Teschan PE. Prophylactic daily hemodialysis. Transactions of The American Society for Artificial Internal Organs. 1959; 5:77-80.
  115. O'Brien TF, Baxter CR, Teschan PE. Prophylactic daily hemodialysis. Transaction of The American Society for Artificial Internal Organs. 1959; 5:76 - 82.
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.