Harvard Catalyst Profiles

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Matthew Nehs, M.D.

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Biography
Hope College, Holland MIBS05/2002Biology and Chemistry
University of Michigan, Ann Arbor, MIMD05/2006Medical School
Brigham and Women's / Harvard Medical School, Boston, MA6/2013General Surgery
Brigham and Women's / Harvard Medical School, Boston, MA7/2014Endocrine Surgery
2022
Wilson Award - Faculty Award for Teaching of Senior Surgical Residents
2022
Murray-Simonian Prize for Research Excellence in Surgery
2019
Thyroid Cancer Survivors Network Research Grant
2016
Matson Award for Faculty Teaching of Residents
2013
Francis D. Moore Chief Resident Award
2012
Harvard Medical School - Excellence in Surgery Research Award
2012
Harvard Medical School Resident Teaching Award
2011
Best Basic Science Oral Presentation – American Association of Endocrine Surgeons
2011
Harvard Medical School Resident Teaching Award
2010
First place, Resident Competition – Massachusetts Chapter of the ACS
2010
Excellence in Research Award – American College of Surgeons
2010
Best Basic Science Oral Presentation – American Association of Endocrine Surgeons
2009
Mannick Research Award – Role of B-Raf in aggressive papillary thyroid cancer
2009
First place, Basic Science Poster – American Association of Endocrine Surgeons

Overview
My scientific interest lies in interaction between metabolism and aggressive malignancies like anaplastic thyroid cancer and adrenocortical carcinoma. We are currently testing the ways in which diet influences tumor growth and also how it modifies the response to treatment.


My clinical practice is a high-volume Endocrine Surgery practice where I treat patients with diseases of the thyroid, parathyroid, and adrenal glands.

Thyroid: I perform more than 100 thyroidectomies per year for both benign and malignant indications. I have a particular interest in treating the most advance thyroid malignancies (Anaplastic, poorly differentiated, medullary).

Parathyroid: Primary hyperparathyroidism is an under-diagnosed condition that can affect bone mineral density, neurocognitive function, and kidney stone formation. Most PHPT is caused by a single parathyroid adenoma in the neck and can be readily cured with surgery.

Adrenal: Diseases of the adrenal glands range from benign functional disorders (pheochromocytoma, aldosteronoma, adrenal Cushing syndrome from an adenoma) to advanced malignancies (Adrenocortical carcinoma and malignant tumors from other sites that metastasize to the adrenal gland). Most adrenalectomies are performed with minimally invasive techniques.

Bibliographic
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.