Harvard Catalyst Profiles

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Joao A Paulo, Ph.D.


The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. R01GM132129 (PAULO, JOAO A) Sep 15, 2019 - Aug 31, 2024
    Advancing Multiplexed Isobaric Tag-based Strategies for Proteome Profiling
    Role: Principal Investigator
  2. K01DK098285 (PAULO, JOAO A) Sep 16, 2013 - Nov 30, 2018
    Resolving the role of nicotine-mediated phosphorylation on pancreatic fibrosis
    Role: Principal Investigator
  3. F32DK085835 (PAULO, JOAO A) May 1, 2010 - Apr 30, 2013
    Proteomics of Pancreatic Fluid and Urine in Chronic Pancreatitis
    Role: Principal Investigator

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Mena EL, Donahue CJ, Vaites LP, Li J, Rona G, O'Leary C, Lignitto L, Miwatani-Minter B, Paulo JA, Dhabaria A, Ueberheide B, Gygi SP, Pagano M, Harper JW, Davey RA, Elledge SJ. ORF10-Cullin-2-ZYG11B complex is not required for SARS-CoV-2 infection. Proc Natl Acad Sci U S A. 2021 04 27; 118(17). PMID: 33827988.
    Citations:    Fields:    Translation:HumansCells
  2. Li J, Cai Z, Bomgarden RD, Pike I, Kuhn K, Rogers JC, Roberts TM, Gygi SP, Paulo JA. TMTpro-18plex: The Expanded and Complete Set of TMTpro Reagents for Sample Multiplexing. J Proteome Res. 2021 Apr 26. PMID: 33900084.
    Citations:    Fields:    
  3. Navarrete-Perea J, Gygi SP, Paulo JA. Temporal proteomic changes induced by nicotine in human cells: A quantitative proteomics approach. J Proteomics. 2021 Apr 23; 241:104244. PMID: 33895337.
    Citations:    Fields:    
  4. Schnell HM, Walsh RM, Rawson S, Kaur M, Bhanu MK, Tian G, Prado MA, Guerra-Moreno A, Paulo JA, Gygi SP, Roelofs J, Finley D, Hanna J. Structures of chaperone-associated assembly intermediates reveal coordinated mechanisms of proteasome biogenesis. Nat Struct Mol Biol. 2021 Apr 12. PMID: 33846632.
    Citations: 1     Fields:    
  5. Ghila L, Legøy TA, Mathisen AF, Abadpour S, Paulo JA, Scholz H, Ræder H, Chera S. Chronically Elevated Exogenous Glucose Elicits Antipodal Effects on the Proteome Signature of Differentiating Human iPSC-Derived Pancreatic Progenitors. Int J Mol Sci. 2021 Apr 02; 22(7). PMID: 33918250.
    Citations:    Fields:    
  6. Navarrete-Perea J, Guerra-Moreno A, Van Vranken J, Isasa M, Paulo JA, Gygi SP. Iron Deficiency and Recovery in Yeast: A Quantitative Proteomics Approach. J Proteome Res. 2021 Apr 02. PMID: 33797912.
    Citations:    Fields:    
  7. Paulo JA, Schweppe DK. Advances in quantitative high-throughput phosphoproteomics with sample multiplexing. Proteomics. 2021 May; 21(9):e2000140. PMID: 33455035.
    Citations:    Fields:    
  8. Zhang T, Keele GR, Churchill GA, Gygi SP, Paulo JA. Strain-Specific Peptide (SSP) Interference Reference Sample: A Genetically Encoded Quality Control for Isobaric Tagging Strategies. Anal Chem. 2021 03 30; 93(12):5241-5247. PMID: 33735571.
    Citations:    Fields:    
  9. Hollingsworth LR, Sharif H, Griswold AR, Fontana P, Mintseris J, Dagbay KB, Paulo JA, Gygi SP, Bachovchin DA, Wu H. DPP9 sequesters the C terminus of NLRP1 to repress inflammasome activation. Nature. 2021 Apr; 592(7856):778-783. PMID: 33731932.
    Citations:    Fields:    
  10. Ordureau A, Yu Q, Bomgarden RD, Rogers JC, Harper JW, Gygi SP, Paulo JA. Super Heavy TMTpro Labeling Reagent: An Alternative and Higher-Charge-State-Amenable Stable-Isotope-Labeled TMTpro Variant. J Proteome Res. 2021 Mar 10. PMID: 33689365.
    Citations:    Fields:    
  11. Cao C, Prado MA, Sun L, Rockowitz S, Sliz P, Paulo JA, Finley D, Fleming MD. Maternal Iron Deficiency Modulates Placental Transcriptome and Proteome in Mid-Gestation of Mouse Pregnancy. J Nutr. 2021 Mar 09. PMID: 33693820.
    Citations:    Fields:    
  12. Lee JD, Paulo JA, Posey RR, Mugoni V, Kong NR, Cheloni G, Lee YR, Slack FJ, Tenen DG, Clohessy JG, Gygi SP, Pandolfi PP. Dual DNA and protein tagging of open chromatin unveils dynamics of epigenomic landscapes in leukemia. Nat Methods. 2021 03; 18(3):293-302. PMID: 33649590.
    Citations:    Fields:    Translation:HumansCells
  13. Gassaway BM, Paulo JA, Gygi SP. Categorization of Phosphorylation Site Behavior during the Diauxic Shift in Saccharomyces cerevisiae. J Proteome Res. 2021 Feb 25. PMID: 33630598.
    Citations:    Fields:    
  14. O'Connell LA, O'Connell JD, Paulo JA, Trauger SA, Gygi SP, Murray AW. Rapid toxin sequestration modifies poison frog physiology. J Exp Biol. 2021 Feb 09; 224(Pt 3). PMID: 33408255.
    Citations:    Fields:    
  15. Mukhopadhyay S, Biancur DE, Parker SJ, Yamamoto K, Banh RS, Paulo JA, Mancias JD, Kimmelman AC. Autophagy is required for proper cysteine homeostasis in pancreatic cancer through regulation of SLC7A11. Proc Natl Acad Sci U S A. 2021 Feb 09; 118(6). PMID: 33531365.
    Citations:    Fields:    
  16. Wong SJ, Ringel AE, Yuan W, Paulo JA, Yoon H, Currie MA, Haigis MC. Development of a colorimetric a-ketoglutarate detection assay for prolyl hydroxylase domain (PHD) proteins. J Biol Chem. 2021 Feb 08; 100397. PMID: 33571527.
    Citations:    Fields:    
  17. Koduri V, Duplaquet L, Lampson BL, Wang AC, Sabet AH, Ishoey M, Paulk J, Teng M, Harris IS, Endress JE, Liu X, Dasilva E, Paulo JA, Briggs KJ, Doench JG, Ott CJ, Zhang T, Donovan KA, Fischer ES, Gygi SP, Gray NS, Bradner J, Medin JA, Buhrlage SJ, Oser MG, Kaelin WG. Targeting oncoproteins with a positive selection assay for protein degraders. Sci Adv. 2021 Feb; 7(6). PMID: 33547076.
    Citations:    Fields:    
  18. Levine ZG, Potter SC, Joiner CM, Fei GQ, Nabet B, Sonnett M, Zachara NE, Gray NS, Paulo JA, Walker S. Mammalian cell proliferation requires noncatalytic functions of O-GlcNAc transferase. Proc Natl Acad Sci U S A. 2021 Jan 26; 118(4). PMID: 33419956.
    Citations: 1     Fields:    
  19. Liu Y, Mei Y, Han X, Korobova FV, Prado MA, Yang J, Peng Z, Paulo JA, Gygi SP, Finley D, Ji P. Membrane skeleton modulates erythroid proteome remodeling and organelle clearance. Blood. 2021 Jan 21; 137(3):398-409. PMID: 33036023.
    Citations:    Fields:    
  20. Rossio V, Paulo JA, Chick J, Brasher B, Gygi SP, King RW. Proteomics of broad deubiquitylase inhibition unmasks redundant enzyme function to reveal substrates and assess enzyme specificity. Cell Chem Biol. 2021 Apr 15; 28(4):487-502.e5. PMID: 33417828.
    Citations:    Fields:    
  21. Whiteley AM, Prado MA, de Poot SAH, Paulo JA, Ashton M, Dominguez S, Weber M, Ngu H, Szpyt J, Jedrychowski MP, Easton A, Gygi SP, Kurz T, Monteiro MJ, Brown EJ, Finley D. Global proteomics of Ubqln2-based murine models of ALS. J Biol Chem. 2020 Dec 04. PMID: 33277362.
    Citations:    Fields:    
  22. Navarrete-Perea J, Gygi SP, Paulo JA. HYpro16: A Two-Proteome Mixture to Assess Interference in Isobaric Tag-Based Sample Multiplexing Experiments. J Am Soc Mass Spectrom. 2021 Jan 06; 32(1):247-254. PMID: 33175540.
    Citations:    Fields:    
  23. Liu X, Gygi SP, Paulo JA. Isobaric Tag-Based Protein Profiling across Eight Human Cell Lines Using High-Field Asymmetric Ion Mobility Spectrometry and Real-Time Database Searching. Proteomics. 2021 01; 21(1):e2000218. PMID: 33015980.
    Citations:    Fields:    
  24. Zhang T, Gygi SP, Paulo JA. Temporal Proteomic Profiling of SH-SY5Y Differentiation with Retinoic Acid Using FAIMS and Real-Time Searching. J Proteome Res. 2021 01 01; 20(1):704-714. PMID: 33054241.
    Citations:    Fields:    
  25. Navarrete-Perea J, Gygi SP, Paulo JA. Growth media selection alters the proteome profiles of three model microorganisms. J Proteomics. 2021 01 16; 231:104006. PMID: 33038513.
    Citations:    Fields:    
  26. E Costa RAP, Granato DC, Trino LD, Yokoo S, Carnielli CM, Kawahara R, Domingues RR, Pauletti BA, Neves LX, Santana AG, Paulo JA, Aragão AZB, Heleno Batista FA, Migliorini Figueira AC, Laurindo FRM, Fernandes D, Hansen HP, Squina F, Gygi SP, Paes Leme AF. ADAM17 cytoplasmic domain modulates Thioredoxin-1 conformation and activity. Redox Biol. 2020 10; 37:101735. PMID: 33011677.
    Citations:    Fields:    
  27. Gerashchenko MV, Nesterchuk MV, Smekalova EM, Paulo JA, Kowalski PS, Akulich KA, Bogorad R, Dmitriev SE, Gygi S, Zatsepin T, Anderson DG, Gladyshev VN, Koteliansky VE. Translation elongation factor 2 depletion by siRNA in mouse liver leads to mTOR-independent translational upregulation of ribosomal protein genes. Sci Rep. 2020 09 23; 10(1):15473. PMID: 32968084.
    Citations: 2     Fields:    Translation:AnimalsCells
  28. Reddy A, Bozi LHM, Yaghi OK, Mills EL, Xiao H, Nicholson HE, Paschini M, Paulo JA, Garrity R, Laznik-Bogoslavski D, Ferreira JCB, Carl CS, Sjøberg KA, Wojtaszewski JFP, Jeppesen JF, Kiens B, Gygi SP, Richter EA, Mathis D, Chouchani ET. pH-Gated Succinate Secretion Regulates Muscle Remodeling in Response to Exercise. Cell. 2020 Oct 01; 183(1):62-75.e17. PMID: 32946811.
    Citations: 1     Fields:    
  29. Nowinski SM, Solmonson A, Rusin SF, Maschek JA, Bensard CL, Fogarty S, Jeong MY, Lettlova S, Berg JA, Morgan JT, Ouyang Y, Naylor BC, Paulo JA, Funai K, Cox JE, Gygi SP, Winge DR, DeBerardinis RJ, Rutter J. Mitochondrial fatty acid synthesis coordinates oxidative metabolism in mammalian mitochondria. Elife. 2020 08 17; 9. PMID: 32804083.
    Citations: 4     Fields:    Translation:HumansAnimalsCells
  30. Sinha NK, Ordureau A, Best K, Saba JA, Zinshteyn B, Sundaramoorthy E, Fulzele A, Garshott DM, Denk T, Thoms M, Paulo JA, Harper JW, Bennett EJ, Beckmann R, Green R. EDF1 coordinates cellular responses to ribosome collisions. Elife. 2020 08 03; 9. PMID: 32744497.
    Citations: 9     Fields:    Translation:HumansCells
  31. Paul AS, Miliu A, Paulo JA, Goldberg JM, Bonilla AM, Berry L, Seveno M, Braun-Breton C, Kosber AL, Elsworth B, Arriola JSN, Lebrun M, Gygi SP, Lamarque MH, Duraisingh MT. Co-option of Plasmodium falciparum PP1 for egress from host erythrocytes. Nat Commun. 2020 07 15; 11(1):3532. PMID: 32669539.
    Citations: 3     Fields:    Translation:HumansAnimalsCells
  32. Yoon H, Spinelli JB, Zaganjor E, Wong SJ, German NJ, Randall EC, Dean A, Clermont A, Paulo JA, Garcia D, Li H, Rombold O, Agar NYR, Goodyear LJ, Shaw RJ, Gygi SP, Auwerx J, Haigis MC. PHD3 Loss Promotes Exercise Capacity and Fat Oxidation in Skeletal Muscle. Cell Metab. 2020 Aug 04; 32(2):215-228.e7. PMID: 32663458.
    Citations:    Fields:    
  33. An H, Ordureau A, Körner M, Paulo JA, Harper JW. Systematic quantitative analysis of ribosome inventory during nutrient stress. Nature. 2020 07; 583(7815):303-309. PMID: 32612236.
    Citations: 4     Fields:    Translation:HumansCells
  34. Tan ZW, Fei G, Paulo JA, Bellaousov S, Martin SES, Duveau DY, Thomas CJ, Gygi SP, Boutz PL, Walker S. O-GlcNAc regulates gene expression by controlling detained intron splicing. Nucleic Acids Res. 2020 06 04; 48(10):5656-5669. PMID: 32329777.
    Citations: 8     Fields:    Translation:HumansCells
  35. Li X, Pritykin Y, Concepcion CP, Lu Y, La Rocca G, Zhang M, King B, Cook PJ, Au YW, Popow O, Paulo JA, Otis HG, Mastroleo C, Ogrodowski P, Schreiner R, Haigis KM, Betel D, Leslie CS, Ventura A. High-Resolution In Vivo Identification of miRNA Targets by Halo-Enhanced Ago2 Pull-Down. Mol Cell. 2020 07 02; 79(1):167-179.e11. PMID: 32497496.
    Citations: 2     Fields:    Translation:AnimalsCells
  36. Park DE, Cheng J, McGrath JP, Lim MY, Cushman C, Swanson SK, Tillgren ML, Paulo JA, Gokhale PC, Florens L, Washburn MP, Trojer P, DeCaprio JA. Author Correction: Merkel cell polyomavirus activates LSD1-mediated blockade of non-canonical BAF to regulate transformation and tumorigenesis. Nat Cell Biol. 2020 06; 22(6):752. PMID: 32415271.
    Citations:    Fields:    
  37. Jedrychowski MP, Lu GZ, Szpyt J, Mariotti M, Garrity R, Paulo JA, Schweppe DK, Laznik-Bogoslavski D, Kazak L, Murphy MP, Gladyshev VN, Gygi SP, Chouchani ET, Spiegelman BM. Facultative protein selenation regulates redox sensitivity, adipose tissue thermogenesis, and obesity. Proc Natl Acad Sci U S A. 2020 05 19; 117(20):10789-10796. PMID: 32358195.
    Citations: 3     Fields:    Translation:AnimalsCells
  38. Parker SJ, Amendola CR, Hollinshead KER, Yu Q, Yamamoto K, Encarnación-Rosado J, Rose RE, LaRue MM, Sohn ASW, Biancur DE, Paulo JA, Gygi SP, Jones DR, Wang H, Philips MR, Bar-Sagi D, Mancias JD, Kimmelman AC. Selective Alanine Transporter Utilization Creates a Targetable Metabolic Niche in Pancreatic Cancer. Cancer Discov. 2020 Jul; 10(7):1018-1037. PMID: 32341021.
    Citations: 12     Fields:    
  39. Sun Y, Ning X, Fan J, Hu J, Jiang Y, Hu Z, Paulo JA, Liu J, Qiu X, Xu H, Fu S, Gygi SP, Zhang J, Zhou C. Loss of tumor suppressor inositol polyphosphate 4-phosphatase type B impairs DNA double-strand break repair by destabilization of DNA tethering protein Rad50. Cell Death Dis. 2020 04 27; 11(4):292. PMID: 32341333.
    Citations:    Fields:    Translation:HumansCells
  40. Yamamoto K, Venida A, Yano J, Biancur DE, Kakiuchi M, Gupta S, Sohn ASW, Mukhopadhyay S, Lin EY, Parker SJ, Banh RS, Paulo JA, Wen KW, Debnath J, Kim GE, Mancias JD, Fearon DT, Perera RM, Kimmelman AC. Autophagy promotes immune evasion of pancreatic cancer by degrading MHC-I. Nature. 2020 05; 581(7806):100-105. PMID: 32376951.
    Citations: 65     Fields:    Translation:HumansAnimalsCells
  41. Yu Q, Paulo JA, Naverrete-Perea J, McAlister GC, Canterbury JD, Bailey DJ, Robitaille AM, Huguet R, Zabrouskov V, Gygi SP, Schweppe DK. Benchmarking the Orbitrap Tribrid Eclipse for Next Generation Multiplexed Proteomics. Anal Chem. 2020 05 05; 92(9):6478-6485. PMID: 32250601.
    Citations: 2     Fields:    
  42. Park DE, Cheng J, McGrath JP, Lim MY, Cushman C, Swanson SK, Tillgren ML, Paulo JA, Gokhale PC, Florens L, Washburn MP, Trojer P, DeCaprio JA. Merkel cell polyomavirus activates LSD1-mediated blockade of non-canonical BAF to regulate transformation and tumorigenesis. Nat Cell Biol. 2020 05; 22(5):603-615. PMID: 32284543.
    Citations: 5     Fields:    
  43. Li J, Van Vranken JG, Paulo JA, Huttlin EL, Gygi SP. Selection of Heating Temperatures Improves the Sensitivity of the Proteome Integral Solubility Alteration Assay. J Proteome Res. 2020 05 01; 19(5):2159-2166. PMID: 32243163.
    Citations: 1     Fields:    
  44. Schweppe DK, Eng JK, Yu Q, Bailey D, Rad R, Navarrete-Perea J, Huttlin EL, Erickson BK, Paulo JA, Gygi SP. Full-Featured, Real-Time Database Searching Platform Enables Fast and Accurate Multiplexed Quantitative Proteomics. J Proteome Res. 2020 05 01; 19(5):2026-2034. PMID: 32126768.
    Citations: 10     Fields:    
  45. Gygi JP, Navarrete-Perea J, Younesi S, Gygi SP, Paulo JA. A Triple Knockout Isobaric-Labeling Quality Control Platform with an Integrated Online Database Search. J Am Soc Mass Spectrom. 2020 Jul 01; 31(7):1344-1349. PMID: 32202424.
    Citations: 2     Fields:    Translation:Animals
  46. Sharma S, Zhang T, Michowski W, Rebecca VW, Xiao M, Ferretti R, Suski JM, Bronson RT, Paulo JA, Frederick D, Fassl A, Boland GM, Geng Y, Lees JA, Medema RH, Herlyn M, Gygi SP, Sicinski P. Targeting the cyclin-dependent kinase 5 in metastatic melanoma. Proc Natl Acad Sci U S A. 2020 04 07; 117(14):8001-8012. PMID: 32193336.
    Citations: 3     Fields:    Translation:HumansAnimalsCells
  47. Cabal-Hierro L, van Galen P, Prado MA, Higby KJ, Togami K, Mowery CT, Paulo JA, Xie Y, Cejas P, Furusawa T, Bustin M, Long HW, Sykes DB, Gygi SP, Finley D, Bernstein BE, Lane AA. Chromatin accessibility promotes hematopoietic and leukemia stem cell activity. Nat Commun. 2020 03 16; 11(1):1406. PMID: 32179749.
    Citations: 3     Fields:    Translation:HumansAnimalsCells
  48. Li J, Van Vranken JG, Pontano Vaites L, Schweppe DK, Huttlin EL, Etienne C, Nandhikonda P, Viner R, Robitaille AM, Thompson AH, Kuhn K, Pike I, Bomgarden RD, Rogers JC, Gygi SP, Paulo JA. TMTpro reagents: a set of isobaric labeling mass tags enables simultaneous proteome-wide measurements across 16 samples. Nat Methods. 2020 04; 17(4):399-404. PMID: 32203386.
    Citations: 20     Fields:    Translation:HumansCells
  49. Richeson KV, Bodrug T, Sackton KL, Yamaguchi M, Paulo JA, Gygi SP, Schulman BA, Brown NG, King RW. Paradoxical mitotic exit induced by a small molecule inhibitor of APC/CCdc20. Nat Chem Biol. 2020 05; 16(5):546-555. PMID: 32152539.
    Citations: 3     Fields:    Translation:HumansCells
  50. Ordureau A, Paulo JA, Zhang J, An H, Swatek KN, Cannon JR, Wan Q, Komander D, Harper JW. Global Landscape and Dynamics of Parkin and USP30-Dependent Ubiquitylomes in iNeurons during Mitophagic Signaling. Mol Cell. 2020 03 05; 77(5):1124-1142.e10. PMID: 32142685.
    Citations: 20     Fields:    Translation:HumansCells
  51. Xiao H, Jedrychowski MP, Schweppe DK, Huttlin EL, Yu Q, Heppner DE, Li J, Long J, Mills EL, Szpyt J, He Z, Du G, Garrity R, Reddy A, Vaites LP, Paulo JA, Zhang T, Gray NS, Gygi SP, Chouchani ET. A Quantitative Tissue-Specific Landscape of Protein Redox Regulation during Aging. Cell. 2020 03 05; 180(5):968-983.e24. PMID: 32109415.
    Citations: 25     Fields:    Translation:HumansAnimalsCells
  52. Legøy TA, Mathisen AF, Salim Z, Vethe H, Bjørlykke Y, Abadpour S, Paulo JA, Scholz H, Ræder H, Ghila L, Chera S. In vivo Environment Swiftly Restricts Human Pancreatic Progenitors Toward Mono-Hormonal Identity via a HNF1A/HNF4A Mechanism. Front Cell Dev Biol. 2020; 8:109. PMID: 32161757.
    Citations: 2     
  53. Loo LSW, Vethe H, Soetedjo AAP, Paulo JA, Jasmen J, Jackson N, Bjørlykke Y, Valdez IA, Vaudel M, Barsnes H, Gygi SP, Raeder H, Teo AKK, Kulkarni RN. Dynamic proteome profiling of human pluripotent stem cell-derived pancreatic progenitors. Stem Cells. 2020 04; 38(4):542-555. PMID: 31828876.
    Citations: 1     Fields:    Translation:HumansCells
  54. Giacomantonio MA, Sterea AM, Kim Y, Paulo JA, Clements DR, Kennedy BE, Bydoun MJ, Shi G, Waisman DM, Gygi SP, Giacomantonio CA, Murphy JP, Gujar S. Quantitative Proteome Responses to Oncolytic Reovirus in GM-CSF- and M-CSF-Differentiated Bone Marrow-Derived Cells. J Proteome Res. 2020 02 07; 19(2):708-718. PMID: 31884793.
    Citations:    Fields:    
  55. Legøy TA, Vethe H, Abadpour S, Strand BL, Scholz H, Paulo JA, Ræder H, Ghila L, Chera S. Encapsulation boosts islet-cell signature in differentiating human induced pluripotent stem cells via integrin signalling. Sci Rep. 2020 01 15; 10(1):414. PMID: 31942009.
    Citations: 9     Fields:    Translation:HumansCells
  56. Legøy TA, Ghila L, Vethe H, Abadpour S, Mathisen AF, Paulo JA, Scholz H, Raeder H, Chera S. In vivo hyperglycaemia exposure elicits distinct period-dependent effects on human pancreatic progenitor differentiation, conveyed by oxidative stress. Acta Physiol (Oxf). 2020 04; 228(4):e13433. PMID: 31872528.
    Citations: 1     Fields:    
  57. Ahfeldt T, Ordureau A, Bell C, Sarrafha L, Sun C, Piccinotti S, Grass T, Parfitt GM, Paulo JA, Yanagawa F, Uozumi T, Kiyota Y, Harper JW, Rubin LL. Pathogenic Pathways in Early-Onset Autosomal Recessive Parkinson's Disease Discovered Using Isogenic Human Dopaminergic Neurons. Stem Cell Reports. 2020 01 14; 14(1):75-90. PMID: 31902706.
    Citations: 4     Fields:    Translation:HumansCells
  58. Schweppe DK, Rusin SF, Gygi SP, Paulo JA. Optimized Workflow for Multiplexed Phosphorylation Analysis of TMT-Labeled Peptides Using High-Field Asymmetric Waveform Ion Mobility Spectrometry. J Proteome Res. 2020 01 03; 19(1):554-560. PMID: 31799850.
    Citations: 2     Fields:    Translation:Cells
  59. Iglesias N, Paulo JA, Tatarakis A, Wang X, Edwards AL, Bhanu NV, Garcia BA, Haas W, Gygi SP, Moazed D. Native Chromatin Proteomics Reveals a Role for Specific Nucleoporins in Heterochromatin Organization and Maintenance. Mol Cell. 2020 01 02; 77(1):51-66.e8. PMID: 31784357.
    Citations: 6     Fields:    Translation:AnimalsCells
  60. Guerra-Moreno A, Prado MA, Ang J, Schnell HM, Micoogullari Y, Paulo JA, Finley D, Gygi SP, Hanna J. Thiol-based direct threat sensing by the stress-activated protein kinase Hog1. Sci Signal. 2019 11 26; 12(609). PMID: 31772124.
    Citations: 1     Fields:    Translation:AnimalsCells
  61. Li J, Paulo JA, Nusinow DP, Huttlin EL, Gygi SP. Investigation of Proteomic and Phosphoproteomic Responses to Signaling Network Perturbations Reveals Functional Pathway Organizations in Yeast. Cell Rep. 2019 11 12; 29(7):2092-2104.e4. PMID: 31722220.
    Citations: 4     Fields:    Translation:AnimalsCells
  62. Heo JM, Harper NJ, Paulo JA, Li M, Xu Q, Coughlin M, Elledge SJ, Harper JW. Integrated proteogenetic analysis reveals the landscape of a mitochondrial-autophagosome synapse during PARK2-dependent mitophagy. Sci Adv. 2019 11; 5(11):eaay4624. PMID: 31723608.
    Citations: 3     Fields:    Translation:HumansCells
  63. Mulcahy MJ, Huard SM, Paulo JA, Wang JH, McKinney S, Henderson BJ, Lester HA. Brain Region-Specific nAChR and Associated Protein Abundance Alterations Following Chronic Nicotine and/or Menthol Exposure. J Proteome Res. 2020 01 03; 19(1):36-48. PMID: 31657575.
    Citations: 1     Fields:    
  64. Paulo JA, Navarrete-Perea J, Gygi SP. Multiplexed proteome profiling of carbon source perturbations in two yeast species with SL-SP3-TMT. J Proteomics. 2020 01 06; 210:103531. PMID: 31626996.
    Citations: 3     Fields:    Translation:Animals
  65. Lim MY, Paulo JA, Gygi SP. Evaluating False Transfer Rates from the Match-between-Runs Algorithm with a Two-Proteome Model. J Proteome Res. 2019 11 01; 18(11):4020-4026. PMID: 31547658.
    Citations: 6     Fields:    Translation:HumansAnimalsCells
  66. Paulo JA, Gygi SP. mTMT: An Alternative, Nonisobaric, Tandem Mass Tag Allowing for Precursor-Based Quantification. Anal Chem. 2019 10 01; 91(19):12167-12172. PMID: 31490667.
    Citations:    Fields:    Translation:HumansCells
  67. Brubaker DK, Paulo JA, Sheth S, Poulin EJ, Popow O, Joughin BA, Strasser SD, Starchenko A, Gygi SP, Lauffenburger DA, Haigis KM. Proteogenomic Network Analysis of Context-Specific KRAS Signaling in Mouse-to-Human Cross-Species Translation. Cell Syst. 2019 09 25; 9(3):258-270.e6. PMID: 31521603.
    Citations: 7     Fields:    Translation:HumansAnimalsCells
  68. Nissim S, Leshchiner I, Mancias JD, Greenblatt MB, Maertens O, Cassa CA, Rosenfeld JA, Cox AG, Hedgepeth J, Wucherpfennig JI, Kim AJ, Henderson JE, Gonyo P, Brandt A, Lorimer E, Unger B, Prokop JW, Heidel JR, Wang XX, Ukaegbu CI, Jennings BC, Paulo JA, Gableske S, Fierke CA, Getz G, Sunyaev SR, Wade Harper J, Cichowski K, Kimmelman AC, Houvras Y, Syngal S, Williams C, Goessling W. Mutations in RABL3 alter KRAS prenylation and are associated with hereditary pancreatic cancer. Nat Genet. 2019 09; 51(9):1308-1314. PMID: 31406347.
    Citations: 11     Fields:    Translation:HumansAnimalsCells
  69. Wang LW, Shen H, Nobre L, Ersing I, Paulo JA, Trudeau S, Wang Z, Smith NA, Ma Y, Reinstadler B, Nomburg J, Sommermann T, Cahir-McFarland E, Gygi SP, Mootha VK, Weekes MP, Gewurz BE. Epstein-Barr-Virus-Induced One-Carbon Metabolism Drives B Cell Transformation. Cell Metab. 2019 09 03; 30(3):539-555.e11. PMID: 31257153.
    Citations: 16     Fields:    Translation:HumansCells
  70. Brennan CM, Vaites LP, Wells JN, Santaguida S, Paulo JA, Storchova Z, Harper JW, Marsh JA, Amon A. Protein aggregation mediates stoichiometry of protein complexes in aneuploid cells. Genes Dev. 2019 08 01; 33(15-16):1031-1047. PMID: 31196865.
    Citations: 18     Fields:    Translation:HumansAnimalsCells
  71. Popow O, Paulo JA, Tatham MH, Volk MS, Rojas-Fernandez A, Loyer N, Newton IP, Januschke J, Haigis KM, Näthke I. Identification of Endogenous Adenomatous Polyposis Coli Interaction Partners and ß-Catenin-Independent Targets by Proteomics. Mol Cancer Res. 2019 09; 17(9):1828-1841. PMID: 31160382.
    Citations:    Fields:    Translation:HumansAnimalsCells
  72. Murphy JP, Kim Y, Clements DR, Konda P, Schuster H, Kowalewski DJ, Paulo JA, Cohen AM, Stevanovic S, Gygi SP, Gujar S. Therapy-Induced MHC I Ligands Shape Neo-Antitumor CD8 T Cell Responses during Oncolytic Virus-Based Cancer Immunotherapy. J Proteome Res. 2019 06 07; 18(6):2666-2675. PMID: 31095916.
    Citations: 1     Fields:    Translation:HumansAnimalsCells
  73. Vethe H, Ghila L, Berle M, Hoareau L, Haaland ØA, Scholz H, Paulo JA, Chera S, Ræder H. The Effect of Wnt Pathway Modulators on Human iPSC-Derived Pancreatic Beta Cell Maturation. Front Endocrinol (Lausanne). 2019; 10:293. PMID: 31139151.
    Citations: 8     
  74. An H, Ordureau A, Paulo JA, Shoemaker CJ, Denic V, Harper JW. TEX264 Is an Endoplasmic Reticulum-Resident ATG8-Interacting Protein Critical for ER Remodeling during Nutrient Stress. Mol Cell. 2019 06 06; 74(5):891-908.e10. PMID: 31006537.
    Citations: 39     Fields:    Translation:HumansAnimalsCells
  75. Poulin EJ, Bera AK, Lu J, Lin YJ, Strasser SD, Paulo JA, Huang TQ, Morales C, Yan W, Cook J, Nowak JA, Brubaker DK, Joughin BA, Johnson CW, DeStefanis RA, Ghazi PC, Gondi S, Wales TE, Iacob RE, Bogdanova L, Gierut JJ, Li Y, Engen JR, Perez-Mancera PA, Braun BS, Gygi SP, Lauffenburger DA, Westover KD, Haigis KM. Tissue-Specific Oncogenic Activity of KRASA146T. Cancer Discov. 2019 06; 9(6):738-755. PMID: 30952657.
    Citations: 26     Fields:    Translation:HumansCells
  76. Iuchi S, Paulo JA. Lysine-specific demethylase 2A enhances binding of various nuclear factors to CpG-rich genomic DNAs by action of its CXXC-PHD domain. Sci Rep. 2019 04 02; 9(1):5496. PMID: 30940825.
    Citations:    Fields:    Translation:HumansCells
  77. Piccolis M, Bond LM, Kampmann M, Pulimeno P, Chitraju C, Jayson CBK, Vaites LP, Boland S, Lai ZW, Gabriel KR, Elliott SD, Paulo JA, Harper JW, Weissman JS, Walther TC, Farese RV. Probing the Global Cellular Responses to Lipotoxicity Caused by Saturated Fatty Acids. Mol Cell. 2019 04 04; 74(1):32-44.e8. PMID: 30846318.
    Citations: 23     Fields:    Translation:HumansCells
  78. Schweppe DK, Prasad S, Belford MW, Navarrete-Perea J, Bailey DJ, Huguet R, Jedrychowski MP, Rad R, McAlister G, Abbatiello SE, Woulters ER, Zabrouskov V, Dunyach JJ, Paulo JA, Gygi SP. Characterization and Optimization of Multiplexed Quantitative Analyses Using High-Field Asymmetric-Waveform Ion Mobility Mass Spectrometry. Anal Chem. 2019 03 19; 91(6):4010-4016. PMID: 30672687.
    Citations: 17     Fields:    Translation:HumansAnimalsCells
  79. Murphy JP, Yu Q, Konda P, Paulo JA, Jedrychowski MP, Kowalewski DJ, Schuster H, Kim Y, Clements D, Jain A, Stevanovic S, Gygi SP, Mancias JD, Gujar S. Multiplexed Relative Quantitation with Isobaric Tagging Mass Spectrometry Reveals Class I Major Histocompatibility Complex Ligand Dynamics in Response to Doxorubicin. Anal Chem. 2019 04 16; 91(8):5106-5115. PMID: 30779550.
    Citations: 4     Fields:    Translation:HumansAnimalsCells
  80. Furuyama K, Chera S, van Gurp L, Oropeza D, Ghila L, Damond N, Vethe H, Paulo JA, Joosten AM, Berney T, Bosco D, Dorrell C, Grompe M, Ræder H, Roep BO, Thorel F, Herrera PL. Diabetes relief in mice by glucose-sensing insulin-secreting human a-cells. Nature. 2019 03; 567(7746):43-48. PMID: 30760930.
    Citations: 34     Fields:    Translation:HumansAnimalsCells
  81. Neurohr GE, Terry RL, Lengefeld J, Bonney M, Brittingham GP, Moretto F, Miettinen TP, Vaites LP, Soares LM, Paulo JA, Harper JW, Buratowski S, Manalis S, van Werven FJ, Holt LJ, Amon A. Excessive Cell Growth Causes Cytoplasm Dilution And Contributes to Senescence. Cell. 2019 02 21; 176(5):1083-1097.e18. PMID: 30739799.
    Citations: 42     Fields:    Translation:HumansAnimalsCells
  82. Erickson BK, Mintseris J, Schweppe DK, Navarrete-Perea J, Erickson AR, Nusinow DP, Paulo JA, Gygi SP. Active Instrument Engagement Combined with a Real-Time Database Search for Improved Performance of Sample Multiplexing Workflows. J Proteome Res. 2019 03 01; 18(3):1299-1306. PMID: 30658528.
    Citations: 20     Fields:    Translation:Humans
  83. Ron-Harel N, Notarangelo G, Ghergurovich JM, Paulo JA, Sage PT, Santos D, Satterstrom FK, Gygi SP, Rabinowitz JD, Sharpe AH, Haigis MC. Defective respiration and one-carbon metabolism contribute to impaired naïve T cell activation in aged mice. Proc Natl Acad Sci U S A. 2018 12 26; 115(52):13347-13352. PMID: 30530686.
    Citations: 22     Fields:    Translation:AnimalsCells
  84. Paulo JA, Navarrete-Perea J, Guha Thakurta S, Gygi SP. TKO6: A Peptide Standard To Assess Interference for Unit-Resolved Isobaric Labeling Platforms. J Proteome Res. 2019 01 04; 18(1):565-570. PMID: 30481031.
    Citations: 3     Fields:    
  85. Gygi JP, Yu Q, Navarrete-Perea J, Rad R, Gygi SP, Paulo JA. Web-Based Search Tool for Visualizing Instrument Performance Using the Triple Knockout (TKO) Proteome Standard. J Proteome Res. 2019 02 01; 18(2):687-693. PMID: 30451507.
    Citations: 7     Fields:    
  86. Heo JM, Ordureau A, Swarup S, Paulo JA, Shen K, Sabatini DM, Harper JW. RAB7A phosphorylation by TBK1 promotes mitophagy via the PINK-PARKIN pathway. Sci Adv. 2018 11; 4(11):eaav0443. PMID: 30627666.
    Citations: 21     Fields:    Translation:HumansCells
  87. O'Brien JJ, Gunawardena HP, Paulo JA, Chen X, Ibrahim JG, Gygi SP, Qaqish BF. The effects of nonignorable missing data on label-free mass spectrometry proteomics experiments. Ann Appl Stat. 2018 Dec; 12(4):2075-2095. PMID: 30473739.
    Citations: 4     
  88. Martin SES, Tan ZW, Itkonen HM, Duveau DY, Paulo JA, Janetzko J, Boutz PL, Törk L, Moss FA, Thomas CJ, Gygi SP, Lazarus MB, Walker S. Structure-Based Evolution of Low Nanomolar O-GlcNAc Transferase Inhibitors. J Am Chem Soc. 2018 10 24; 140(42):13542-13545. PMID: 30285435.
    Citations: 15     Fields:    Translation:HumansCells
  89. Mulcahy MJ, Paulo JA, Hawrot E. Proteomic Investigation of Murine Neuronal a7-Nicotinic Acetylcholine Receptor Interacting Proteins. J Proteome Res. 2018 11 02; 17(11):3959-3975. PMID: 30285449.
    Citations: 2     Fields:    Translation:AnimalsCells
  90. Bretones G, Álvarez MG, Arango JR, Rodríguez D, Nadeu F, Prado MA, Valdés-Mas R, Puente DA, Paulo JA, Delgado J, Villamor N, López-Guillermo A, Finley DJ, Gygi SP, Campo E, Quesada V, López-Otín C. Altered patterns of global protein synthesis and translational fidelity in RPS15-mutated chronic lymphocytic leukemia. Blood. 2018 11 29; 132(22):2375-2388. PMID: 30181176.
    Citations: 8     Fields:    Translation:HumansCells
  91. Murphy JP, Giacomantonio MA, Paulo JA, Everley RA, Kennedy BE, Pathak GP, Clements DR, Kim Y, Dai C, Sharif T, Gygi SP, Gujar S. The NAD+ Salvage Pathway Supports PHGDH-Driven Serine Biosynthesis. Cell Rep. 2018 08 28; 24(9):2381-2391.e5. PMID: 30157431.
    Citations: 12     Fields:    Translation:HumansCells
  92. Iglesias N, Currie MA, Jih G, Paulo JA, Siuti N, Kalocsay M, Gygi SP, Moazed D. Automethylation-induced conformational switch in Clr4 (Suv39h) maintains epigenetic stability. Nature. 2018 08; 560(7719):504-508. PMID: 30051891.
    Citations: 12     Fields:    Translation:HumansAnimalsCells
  93. Navarrete-Perea J, Yu Q, Gygi SP, Paulo JA. Streamlined Tandem Mass Tag (SL-TMT) Protocol: An Efficient Strategy for Quantitative (Phospho)proteome Profiling Using Tandem Mass Tag-Synchronous Precursor Selection-MS3. J Proteome Res. 2018 06 01; 17(6):2226-2236. PMID: 29734811.
    Citations: 43     Fields:    Translation:Animals
  94. Paulo JA, Gygi SP. Isobaric Tag-Based Protein Profiling of a Nicotine-Treated Alpha7 Nicotinic Receptor-Null Human Haploid Cell Line. Proteomics. 2018 06; 18(11):e1700475. PMID: 29663646.
    Citations: 4     Fields:    Translation:HumansCells
  95. Paulo JA, Jedrychowski MP, Chouchani ET, Kazak L, Gygi SP. Multiplexed Isobaric Tag-Based Profiling of Seven Murine Tissues Following In Vivo Nicotine Treatment Using a Minimalistic Proteomics Strategy. Proteomics. 2018 05; 18(10):e1700326. PMID: 29660237.
    Citations: 5     Fields:    Translation:Animals
  96. O'Connell JD, Paulo JA, O'Brien JJ, Gygi SP. Proteome-Wide Evaluation of Two Common Protein Quantification Methods. J Proteome Res. 2018 05 04; 17(5):1934-1942. PMID: 29635916.
    Citations: 27     Fields:    
  97. Paulo JA, Navarrete-Perea J, Erickson AR, Knott J, Gygi SP. An Internal Standard for Assessing Phosphopeptide Recovery from Metal Ion/Oxide Enrichment Strategies. J Am Soc Mass Spectrom. 2018 07; 29(7):1505-1511. PMID: 29671274.
    Citations: 6     Fields:    
  98. Ordureau A, Paulo JA, Zhang W, Ahfeldt T, Zhang J, Cohn EF, Hou Z, Heo JM, Rubin LL, Sidhu SS, Gygi SP, Harper JW. Dynamics of PARKIN-Dependent Mitochondrial Ubiquitylation in Induced Neurons and Model Systems Revealed by Digital Snapshot Proteomics. Mol Cell. 2018 04 19; 70(2):211-227.e8. PMID: 29656925.
    Citations: 33     Fields:    Translation:HumansCells
  99. Berberich MJ, Paulo JA, Everley RA. MS3-IDQ: Utilizing MS3 Spectra beyond Quantification Yields Increased Coverage of the Phosphoproteome in Isobaric Tag Experiments. J Proteome Res. 2018 04 06; 17(4):1741-1747. PMID: 29461835.
    Citations: 2     Fields:    Translation:Cells
  100. Stepanova E, Gygi SP, Paulo JA. Filter-Based Protein Digestion (FPD): A Detergent-Free and Scaffold-Based Strategy for TMT Workflows. J Proteome Res. 2018 03 02; 17(3):1227-1234. PMID: 29402085.
    Citations: 4     Fields:    Translation:HumansCells
  101. Fraile JM, Campos-Iglesias D, Rodríguez F, Astudillo A, Vilarrasa-Blasi R, Verdaguer-Dot N, Prado MA, Paulo JA, Gygi SP, Martín-Subero JI, Freije JMP, López-Otín C. Loss of the deubiquitinase USP36 destabilizes the RNA helicase DHX33 and causes preimplantation lethality in mice. J Biol Chem. 2018 02 09; 293(6):2183-2194. PMID: 29273634.
    Citations: 5     Fields:    Translation:HumansAnimalsCells
  102. O'Brien JJ, O'Connell JD, Paulo JA, Thakurta S, Rose CM, Weekes MP, Huttlin EL, Gygi SP. Compositional Proteomics: Effects of Spatial Constraints on Protein Quantification Utilizing Isobaric Tags. J Proteome Res. 2018 01 05; 17(1):590-599. PMID: 29195270.
    Citations: 16     Fields:    
  103. Vaites LP, Paulo JA, Huttlin EL, Harper JW. Systematic Analysis of Human Cells Lacking ATG8 Proteins Uncovers Roles for GABARAPs and the CCZ1/MON1 Regulator C18orf8/RMC1 in Macroautophagic and Selective Autophagic Flux. Mol Cell Biol. 2018 01 01; 38(1). PMID: 29038162.
    Citations: 27     Fields:    Translation:HumansCells
  104. Lim MY, O'Brien J, Paulo JA, Gygi SP. Improved Method for Determining Absolute Phosphorylation Stoichiometry Using Bayesian Statistics and Isobaric Labeling. J Proteome Res. 2017 11 03; 16(11):4217-4226. PMID: 28985074.
    Citations: 7     Fields:    Translation:HumansCells
  105. Navarrete-Perea J, Isasa M, Paulo JA, Corral-Corral R, Flores-Bautista J, Hernández-Téllez B, Bobes RJ, Fragoso G, Sciutto E, Soberón X, Gygi SP, Laclette JP. Quantitative multiplexed proteomics of Taenia solium cysts obtained from the skeletal muscle and central nervous system of pigs. PLoS Negl Trop Dis. 2017 Sep; 11(9):e0005962. PMID: 28945737.
    Citations: 3     Fields:    Translation:Animals
  106. Whiteley AM, Prado MA, Peng I, Abbas AR, Haley B, Paulo JA, Reichelt M, Katakam A, Sagolla M, Modrusan Z, Lee DY, Roose-Girma M, Kirkpatrick DS, McKenzie BS, Gygi SP, Finley D, Brown EJ. Ubiquilin1 promotes antigen-receptor mediated proliferation by eliminating mislocalized mitochondrial proteins. Elife. 2017 09 21; 6. PMID: 28933694.
    Citations: 12     Fields:    Translation:HumansAnimalsCells
  107. Clements DR, Murphy JP, Sterea A, Kennedy BE, Kim Y, Helson E, Almasi S, Holay N, Konda P, Paulo JA, Sharif T, Lee PW, Weekes MP, Gygi SP, Gujar S. Quantitative Temporal in Vivo Proteomics Deciphers the Transition of Virus-Driven Myeloid Cells into M2 Macrophages. J Proteome Res. 2017 09 01; 16(9):3391-3406. PMID: 28768414.
    Citations: 5     Fields:    Translation:AnimalsCells
  108. Nguyen AT, Prado MA, Schmidt PJ, Sendamarai AK, Wilson-Grady JT, Min M, Campagna DR, Tian G, Shi Y, Dederer V, Kawan M, Kuehnle N, Paulo JA, Yao Y, Weiss MJ, Justice MJ, Gygi SP, Fleming MD, Finley D. UBE2O remodels the proteome during terminal erythroid differentiation. Science. 2017 08 04; 357(6350). PMID: 28774900.
    Citations: 37     Fields:    Translation:HumansAnimalsCells
  109. Palmer CJ, Bruckner RJ, Paulo JA, Kazak L, Long JZ, Mina AI, Deng Z, LeClair KB, Hall JA, Hong S, Zushin PH, Smith KL, Gygi SP, Hagen S, Cohen DE, Banks AS. Cdkal1, a type 2 diabetes susceptibility gene, regulates mitochondrial function in adipose tissue. Mol Metab. 2017 10; 6(10):1212-1225. PMID: 29031721.
    Citations: 6     Fields:    Translation:AnimalsCells
  110. Vethe H, Bjørlykke Y, Ghila LM, Paulo JA, Scholz H, Gygi SP, Chera S, Ræder H. Probing the missing mature ß-cell proteomic landscape in differentiating patient iPSC-derived cells. Sci Rep. 2017 07 06; 7(1):4780. PMID: 28684784.
    Citations: 17     Fields:    Translation:HumansCells
  111. Biancur DE, Paulo JA, Malachowska B, Quiles Del Rey M, Sousa CM, Wang X, Sohn ASW, Chu GC, Gygi SP, Harper JW, Fendler W, Mancias JD, Kimmelman AC. Compensatory metabolic networks in pancreatic cancers upon perturbation of glutamine metabolism. Nat Commun. 2017 07 03; 8:15965. PMID: 28671190.
    Citations: 79     Fields:    Translation:HumansAnimalsCells
  112. Jih G, Iglesias N, Currie MA, Bhanu NV, Paulo JA, Gygi SP, Garcia BA, Moazed D. Unique roles for histone H3K9me states in RNAi and heritable silencing of transcription. Nature. 2017 07 27; 547(7664):463-467. PMID: 28682306.
    Citations: 28     Fields:    Translation:AnimalsCells
  113. Scott DC, Hammill JT, Min J, Rhee DY, Connelly M, Sviderskiy VO, Bhasin D, Chen Y, Ong SS, Chai SC, Goktug AN, Huang G, Monda JK, Low J, Kim HS, Paulo JA, Cannon JR, Shelat AA, Chen T, Kelsall IR, Alpi AF, Pagala V, Wang X, Peng J, Singh B, Harper JW, Schulman BA, Guy RK. Blocking an N-terminal acetylation-dependent protein interaction inhibits an E3 ligase. Nat Chem Biol. 2017 Aug; 13(8):850-857. PMID: 28581483.
    Citations: 22     Fields:    Translation:HumansCells
  114. Mohideen F, Paulo JA, Ordureau A, Gygi SP, Harper JW. Quantitative Phospho-proteomic Analysis of TNFa/NF?B Signaling Reveals a Role for RIPK1 Phosphorylation in Suppressing Necrotic Cell Death. Mol Cell Proteomics. 2017 07; 16(7):1200-1216. PMID: 28539327.
    Citations: 5     Fields:    Translation:HumansCells
  115. Huttlin EL, Bruckner RJ, Paulo JA, Cannon JR, Ting L, Baltier K, Colby G, Gebreab F, Gygi MP, Parzen H, Szpyt J, Tam S, Zarraga G, Pontano-Vaites L, Swarup S, White AE, Schweppe DK, Rad R, Erickson BK, Obar RA, Guruharsha KG, Li K, Artavanis-Tsakonas S, Gygi SP, Harper JW. Architecture of the human interactome defines protein communities and disease networks. Nature. 2017 05 25; 545(7655):505-509. PMID: 28514442.
    Citations: 320     Fields:    Translation:HumansCells
  116. Ersing I, Nobre L, Wang LW, Soday L, Ma Y, Paulo JA, Narita Y, Ashbaugh CW, Jiang C, Grayson NE, Kieff E, Gygi SP, Weekes MP, Gewurz BE. A Temporal Proteomic Map of Epstein-Barr Virus Lytic Replication in B Cells. Cell Rep. 2017 05 16; 19(7):1479-1493. PMID: 28514666.
    Citations: 24     Fields:    Translation:HumansCells
  117. Paulo JA, Mancias JD, Gygi SP. Proteome-Wide Protein Expression Profiling Across Five Pancreatic Cell Lines. Pancreas. 2017 May/Jun; 46(5):690-698. PMID: 28375945.
    Citations: 7     Fields:    Translation:HumansCells
  118. Paek J, Kalocsay M, Staus DP, Wingler L, Pascolutti R, Paulo JA, Gygi SP, Kruse AC. Multidimensional Tracking of GPCR Signaling via Peroxidase-Catalyzed Proximity Labeling. Cell. 2017 04 06; 169(2):338-349.e11. PMID: 28388415.
    Citations: 38     Fields:    Translation:HumansCells
  119. Ganter M, Goldberg JM, Dvorin JD, Paulo JA, King JG, Tripathi AK, Paul AS, Yang J, Coppens I, Jiang RH, Elsworth B, Baker DA, Dinglasan RR, Gygi SP, Duraisingh MT. Erratum: Plasmodium falciparum CRK4 directs continuous rounds of DNA replication during schizogony. Nat Microbiol. 2017 Mar 06; 2:17038. PMID: 28263306.
    Citations:    Fields:    
  120. Possemato AP, Paulo JA, Mulhern D, Guo A, Gygi SP, Beausoleil SA. Multiplexed Phosphoproteomic Profiling Using Titanium Dioxide and Immunoaffinity Enrichments Reveals Complementary Phosphorylation Events. J Proteome Res. 2017 04 07; 16(4):1506-1514. PMID: 28171727.
    Citations: 14     Fields:    Translation:HumansCells
  121. Ganter M, Goldberg JM, Dvorin JD, Paulo JA, King JG, Tripathi AK, Paul AS, Yang J, Coppens I, Jiang RH, Elsworth B, Baker DA, Dinglasan RR, Gygi SP, Duraisingh MT. Plasmodium falciparum CRK4 directs continuous rounds of DNA replication during schizogony. Nat Microbiol. 2017 Feb 17; 2:17017. PMID: 28211852.
    Citations: 24     Fields:    Translation:HumansAnimalsCells
  122. Fielding CA, Weekes MP, Nobre LV, Ruckova E, Wilkie GS, Paulo JA, Chang C, Suárez NM, Davies JA, Antrobus R, Stanton RJ, Aicheler RJ, Nichols H, Vojtesek B, Trowsdale J, Davison AJ, Gygi SP, Tomasec P, Lehner PJ, Wilkinson GW. Control of immune ligands by members of a cytomegalovirus gene expansion suppresses natural killer cell activation. Elife. 2017 02 10; 6. PMID: 28186488.
    Citations: 26     Fields:    Translation:HumansCells
  123. Anikster Y, Haack TB, Vilboux T, Pode-Shakked B, Thöny B, Shen N, Guarani V, Meissner T, Mayatepek E, Trefz FK, Marek-Yagel D, Martinez A, Huttlin EL, Paulo JA, Berutti R, Benoist JF, Imbard A, Dorboz I, Heimer G, Landau Y, Ziv-Strasser L, Malicdan MCV, Gemperle-Britschgi C, Cremer K, Engels H, Meili D, Keller I, Bruggmann R, Strom TM, Meitinger T, Mullikin JC, Schwartz G, Ben-Zeev B, Gahl WA, Harper JW, Blau N, Hoffmann GF, Prokisch H, Opladen T, Schiff M. Biallelic Mutations in DNAJC12 Cause Hyperphenylalaninemia, Dystonia, and Intellectual Disability. Am J Hum Genet. 2017 02 02; 100(2):257-266. PMID: 28132689.
    Citations: 21     Fields:    Translation:HumansCells
  124. Erickson BK, Rose CM, Braun CR, Erickson AR, Knott J, McAlister GC, Wühr M, Paulo JA, Everley RA, Gygi SP. A Strategy to Combine Sample Multiplexing with Targeted Proteomics Assays for High-Throughput Protein Signature Characterization. Mol Cell. 2017 Jan 19; 65(2):361-370. PMID: 28065596.
    Citations: 31     Fields:    Translation:HumansCells
  125. Paulo JA, Gygi SP. Nicotine-induced protein expression profiling reveals mutually altered proteins across four human cell lines. Proteomics. 2017 01; 17(1-2). PMID: 27862958.
    Citations: 12     Fields:    Translation:HumansCells
  126. Wu L, Zhou B, Oshiro-Rapley N, Li M, Paulo JA, Webster CM, Mou F, Kacergis MC, Talkowski ME, Carr CE, Gygi SP, Zheng B, Soukas AA. An Ancient, Unified Mechanism for Metformin Growth Inhibition in C. elegans and Cancer. Cell. 2016 Dec 15; 167(7):1705-1718.e13. PMID: 27984722.
    Citations: 61     Fields:    Translation:HumansAnimalsCells
  127. Turnbull ML, Wise HM, Nicol MQ, Smith N, Dunfee RL, Beard PM, Jagger BW, Ligertwood Y, Hardisty GR, Xiao H, Benton DJ, Coburn AM, Paulo JA, Gygi SP, McCauley JW, Taubenberger JK, Lycett SJ, Weekes MP, Dutia BM, Digard P. Role of the B Allele of Influenza A Virus Segment 8 in Setting Mammalian Host Range and Pathogenicity. J Virol. 2016 10 15; 90(20):9263-84. PMID: 27489273.
    Citations: 7     Fields:    Translation:HumansAnimalsCells
  128. Barrow JJ, Balsa E, Verdeguer F, Tavares CD, Soustek MS, Hollingsworth LR, Jedrychowski M, Vogel R, Paulo JA, Smeitink J, Gygi SP, Doench J, Root DE, Puigserver P. Bromodomain Inhibitors Correct Bioenergetic Deficiency Caused by Mitochondrial Disease Complex I Mutations. Mol Cell. 2016 10 06; 64(1):163-175. PMID: 27666594.
    Citations: 10     Fields:    Translation:HumansCells
  129. Guarani V, Jardel C, Chrétien D, Lombès A, Bénit P, Labasse C, Lacène E, Bourillon A, Imbard A, Benoist JF, Dorboz I, Gilleron M, Goetzman ES, Gaignard P, Slama A, Elmaleh-Bergès M, Romero NB, Rustin P, Ogier de Baulny H, Paulo JA, Harper JW, Schiff M. QIL1 mutation causes MICOS disassembly and early onset fatal mitochondrial encephalopathy with liver disease. Elife. 2016 09 13; 5. PMID: 27623147.
    Citations: 11     Fields:    Translation:Humans
  130. Scott DC, Rhee DY, Duda DM, Kelsall IR, Olszewski JL, Paulo JA, de Jong A, Ovaa H, Alpi AF, Harper JW, Schulman BA. Two Distinct Types of E3 Ligases Work in Unison to Regulate Substrate Ubiquitylation. Cell. 2016 Aug 25; 166(5):1198-1214.e24. PMID: 27565346.
    Citations: 49     Fields:    Translation:HumansCells
  131. Paulo JA, O'Connell JD, Everley RA, O'Brien J, Gygi MA, Gygi SP. Quantitative mass spectrometry-based multiplexing compares the abundance of 5000 S. cerevisiae proteins across 10 carbon sources. J Proteomics. 2016 10 04; 148:85-93. PMID: 27432472.
    Citations: 48     Fields:    Translation:Animals
  132. Paulo JA. Sample preparation for proteomic analysis using a GeLC-MS/MS strategy. J Biol Methods. 2016; 3(3). PMID: 27482532.
    Citations: 15     
  133. Paulo JA, O'Connell JD, Gygi SP. A Triple Knockout (TKO) Proteomics Standard for Diagnosing Ion Interference in Isobaric Labeling Experiments. J Am Soc Mass Spectrom. 2016 10; 27(10):1620-5. PMID: 27400695.
    Citations: 46     Fields:    Translation:Animals
  134. Long JZ, Svensson KJ, Bateman LA, Lin H, Kamenecka T, Lokurkar IA, Lou J, Rao RR, Chang MR, Jedrychowski MP, Paulo JA, Gygi SP, Griffin PR, Nomura DK, Spiegelman BM. The Secreted Enzyme PM20D1 Regulates Lipidated Amino Acid Uncouplers of Mitochondria. Cell. 2016 Jul 14; 166(2):424-435. PMID: 27374330.
    Citations: 65     Fields:    Translation:AnimalsCells
  135. Isasa M, Rose CM, Elsasser S, Navarrete-Perea J, Paulo JA, Finley DJ, Gygi SP. Multiplexed, Proteome-Wide Protein Expression Profiling: Yeast Deubiquitylating Enzyme Knockout Strains. J Proteome Res. 2015 Dec 04; 14(12):5306-17. PMID: 26503604.
    Citations: 19     Fields:    Translation:AnimalsCells
  136. Paulo JA, O'Connell JD, Gaun A, Gygi SP. Proteome-wide quantitative multiplexed profiling of protein expression: carbon-source dependency in Saccharomyces cerevisiae. Mol Biol Cell. 2015 Nov 05; 26(22):4063-74. PMID: 26399295.
    Citations: 16     Fields:    Translation:AnimalsCells
  137. Heo JM, Ordureau A, Paulo JA, Rinehart J, Harper JW. The PINK1-PARKIN Mitochondrial Ubiquitylation Pathway Drives a Program of OPTN/NDP52 Recruitment and TBK1 Activation to Promote Mitophagy. Mol Cell. 2015 Oct 01; 60(1):7-20. PMID: 26365381.
    Citations: 218     Fields:    Translation:HumansCells
  138. Paulo JA, Gaun A, Gygi SP. Global Analysis of Protein Expression and Phosphorylation Levels in Nicotine-Treated Pancreatic Stellate Cells. J Proteome Res. 2015 Oct 02; 14(10):4246-56. PMID: 26265067.
    Citations: 28     Fields:    Translation:HumansCells
  139. Jedrychowski MP, Wrann CD, Paulo JA, Gerber KK, Szpyt J, Robinson MM, Nair KS, Gygi SP, Spiegelman BM. Detection and Quantitation of Circulating Human Irisin by Tandem Mass Spectrometry. Cell Metab. 2015 Oct 06; 22(4):734-740. PMID: 26278051.
    Citations: 127     Fields:    Translation:HumansCells
  140. Huttlin EL, Ting L, Bruckner RJ, Gebreab F, Gygi MP, Szpyt J, Tam S, Zarraga G, Colby G, Baltier K, Dong R, Guarani V, Vaites LP, Ordureau A, Rad R, Erickson BK, Wühr M, Chick J, Zhai B, Kolippakkam D, Mintseris J, Obar RA, Harris T, Artavanis-Tsakonas S, Sowa ME, De Camilli P, Paulo JA, Harper JW, Gygi SP. The BioPlex Network: A Systematic Exploration of the Human Interactome. Cell. 2015 Jul 16; 162(2):425-440. PMID: 26186194.
    Citations: 446     Fields:    Translation:Humans
  141. Murphy JP, Stepanova E, Everley RA, Paulo JA, Gygi SP. Comprehensive Temporal Protein Dynamics during the Diauxic Shift in Saccharomyces cerevisiae. Mol Cell Proteomics. 2015 Sep; 14(9):2454-65. PMID: 26077900.
    Citations: 26     Fields:    Translation:Animals
  142. Guarani V, McNeill EM, Paulo JA, Huttlin EL, Fröhlich F, Gygi SP, Van Vactor D, Harper JW. QIL1 is a novel mitochondrial protein required for MICOS complex stability and cristae morphology. Elife. 2015 May 21; 4. PMID: 25997101.
    Citations: 49     Fields:    Translation:HumansAnimalsCells
  143. Ordureau A, Heo JM, Duda DM, Paulo JA, Olszewski JL, Yanishevski D, Rinehart J, Schulman BA, Harper JW. Defining roles of PARKIN and ubiquitin phosphorylation by PINK1 in mitochondrial quality control using a ubiquitin replacement strategy. Proc Natl Acad Sci U S A. 2015 May 26; 112(21):6637-42. PMID: 25969509.
    Citations: 104     Fields:    Translation:HumansCells
  144. Egan ES, Jiang RH, Moechtar MA, Barteneva NS, Weekes MP, Nobre LV, Gygi SP, Paulo JA, Frantzreb C, Tani Y, Takahashi J, Watanabe S, Goldberg J, Paul AS, Brugnara C, Root DE, Wiegand RC, Doench JG, Duraisingh MT. Malaria. A forward genetic screen identifies erythrocyte CD55 as essential for Plasmodium falciparum invasion. Science. 2015 May 08; 348(6235):711-4. PMID: 25954012.
    Citations: 36     Fields:    Translation:HumansAnimalsCells
  145. Marchegiani G, Paulo JA, Sahora K, Fernández-Del Castillo C. The proteome of postsurgical pancreatic juice. Pancreas. 2015 May; 44(4):574-82. PMID: 25875796.
    Citations: 7     Fields:    Translation:HumansCTClinical Trials
  146. Paulo JA, Gygi SP. A comprehensive proteomic and phosphoproteomic analysis of yeast deletion mutants of 14-3-3 orthologs and associated effects of rapamycin. Proteomics. 2015 Jan; 15(2-3):474-86. PMID: 25315811.
    Citations: 27     Fields:    Translation:AnimalsCells
  147. Paulo JA, McAllister FE, Everley RA, Beausoleil SA, Banks AS, Gygi SP. Effects of MEK inhibitors GSK1120212 and PD0325901 in vivo using 10-plex quantitative proteomics and phosphoproteomics. Proteomics. 2015 Jan; 15(2-3):462-73. PMID: 25195567.
    Citations: 30     Fields:    Translation:HumansAnimalsCells
  148. Paulo JA. Nicotine alters the proteome of two human pancreatic duct cell lines. JOP. 2014 Sep 28; 15(5):465-74. PMID: 25262714.
    Citations: 11     Fields:    
  149. Guarani V, Paulo J, Zhai B, Huttlin EL, Gygi SP, Harper JW. TIMMDC1/C3orf1 functions as a membrane-embedded mitochondrial complex I assembly factor through association with the MCIA complex. Mol Cell Biol. 2014 Mar; 34(5):847-61. PMID: 24344204.
    Citations: 34     Fields:    Translation:HumansCells
  150. Low HP, Tiwari A, Janjanam J, Qiu L, Chang CI, Strohsnitter WC, Norwitz ER, Tam SW, Evans JE, Green KM, Paulo JA, Lambe M, Hsieh CC. Screening preeclamptic cord plasma for proteins associated with decreased breast cancer susceptibility. Genomics Proteomics Bioinformatics. 2013 Dec; 11(6):335-44. PMID: 24296084.
    Citations: 3     Fields:    Translation:Humans
  151. Paulo JA. Practical and Efficient Searching in Proteomics: A Cross Engine Comparison. Webmedcentral. 2013 Oct 01; 4(10). PMID: 25346847.
    Citations: 8     
  152. Paulo JA, Kadiyala V, Brizard S, Banks PA, Steen H, Conwell DL. A proteomic comparison of formalin-fixed paraffin-embedded pancreatic tissue from autoimmune pancreatitis, chronic pancreatitis, and pancreatic cancer. JOP. 2013 Jul 10; 14(4):405-14. PMID: 23846938.
    Citations: 5     Fields:    Translation:Humans
  153. Paulo JA, Urrutia R, Kadiyala V, Banks P, Conwell DL, Steen H. Cross-species analysis of nicotine-induced proteomic alterations in pancreatic cells. Proteomics. 2013 May; 13(9):1499-1512. PMID: 23456891.
    Citations: 8     Fields:    Translation:HumansAnimalsCells
  154. Ræder H, Vesterhus M, El Ouaamari A, Paulo JA, McAllister FE, Liew CW, Hu J, Kawamori D, Molven A, Gygi SP, Njølstad PR, Kahn CR, Kulkarni RN. Absence of diabetes and pancreatic exocrine dysfunction in a transgenic model of carboxyl-ester lipase-MODY (maturity-onset diabetes of the young). PLoS One. 2013; 8(4):e60229. PMID: 23565203.
    Citations: 8     Fields:    Translation:Animals
  155. Paulo JA, Kadiyala V, Banks PA, Conwell DL, Steen H. Mass spectrometry-based quantitative proteomic profiling of human pancreatic and hepatic stellate cell lines. Genomics Proteomics Bioinformatics. 2013 Apr; 11(2):105-13. PMID: 23528454.
    Citations: 11     Fields:    Translation:HumansCells
  156. Paulo JA, Kadiyala V, Brizard S, Banks PA, Steen H, Conwell DL. Post-translational modifications of pancreatic fluid proteins collected via the endoscopic pancreatic function test (ePFT). J Proteomics. 2013 Oct 30; 92:216-27. PMID: 23500127.
    Citations: 4     Fields:    Translation:HumansCellsCTClinical Trials
  157. Paulo JA, Kadiyala V, Gaun A, Sauld JF, Ghoulidi A, Banks PA, Steen H, Conwell DL. Analysis of endoscopic pancreatic function test (ePFT)-collected pancreatic fluid proteins precipitated via ultracentrifugation. JOP. 2013 Mar 10; 14(2):176-86. PMID: 23474565.
    Citations: 3     Fields:    Translation:HumansCells
  158. Lusczek ER, Paulo JA, Saltzman JR, Kadiyala V, Banks PA, Beilman G, Conwell DL. Urinary 1H-NMR metabolomics can distinguish pancreatitis patients from healthy controls. JOP. 2013 Mar 10; 14(2):161-70. PMID: 23474563.
    Citations: 9     Fields:    Translation:Humans
  159. Paulo JA, Gaun A, Kadiyala V, Ghoulidi A, Banks PA, Conwell DL, Steen H. Subcellular fractionation enhances proteome coverage of pancreatic duct cells. Biochim Biophys Acta. 2013 Apr; 1834(4):791-7. PMID: 23352835.
    Citations: 4     Fields:    Translation:Cells
  160. Kadiyala V, Lee LS, Banks PA, Suleiman S, Paulo JA, Wang W, Rosenblum J, Sainani NI, Mortele K, Conwell DL. Cigarette smoking impairs pancreatic duct cell bicarbonate secretion. JOP. 2013 Jan 10; 14(1):31-8. PMID: 23306332.
    Citations: 10     Fields:    Translation:Humans
  161. Serang O, Paulo J, Steen H, Steen JA. A non-parametric cutout index for robust evaluation of identified proteins. Mol Cell Proteomics. 2013 Mar; 12(3):807-12. PMID: 23292186.
    Citations: 7     Fields:    Translation:HumansCells
  162. Paulo JA, Kadiyala V, Brizard S, Banks PA, Conwell DL, Steen H. Short Gel, Long Gradient Liquid Chromatography Tandem Mass Spectrometry to Discover Urinary Biomarkers of Chronic Pancreatitis. Open Proteomics J. 2013; 6:1-13. PMID: 25346780.
    Citations: 4     
  163. Lee LS, Bellizzi AM, Banks PA, Sainani NI, Kadiyala V, Suleiman S, Conwell DL, Paulo JA. Differentiating Branch Duct and Mixed IPMN in Endoscopically Collected Pancreatic Cyst Fluid via Cytokine Analysis. Gastroenterol Res Pract. 2012; 2012:247309. PMID: 23326260.
    Citations: 2     
  164. Kentsis A, Shulman A, Ahmed S, Brennan E, Monuteaux MC, Lee YH, Lipsett S, Paulo JA, Dedeoglu F, Fuhlbrigge R, Bachur R, Bradwin G, Arditi M, Sundel RP, Newburger JW, Steen H, Kim S. Urine proteomics for discovery of improved diagnostic markers of Kawasaki disease. EMBO Mol Med. 2013 Feb; 5(2):210-20. PMID: 23281308.
    Citations: 23     Fields:    Translation:HumansAnimalsCells
  165. Lee LS, Banks PA, Bellizzi AM, Sainani NI, Kadiyala V, Suleiman S, Conwell DL, Paulo JA. Inflammatory protein profiling of pancreatic cyst fluid using EUS-FNA in tandem with cytokine microarray differentiates between branch duct IPMN and inflammatory cysts. J Immunol Methods. 2012 Aug 31; 382(1-2):142-149. PMID: 22683544.
    Citations: 12     Fields:    Translation:Humans
  166. Paulo JA, Kadiyala V, Banks PA, Steen H, Conwell DL. Mass Spectrometry-Based (GeLC-MS/MS) Comparative Proteomic Analysis of Endoscopically (ePFT) Collected Pancreatic and Gastroduodenal Fluids. Clin Transl Gastroenterol. 2012 May 03; 3:e14. PMID: 23238231.
    Citations: 5     Fields:    
  167. Paulo JA, Kadiyala V, Banks PA, Steen H, Conwell DL. Mass spectrometry-based proteomics for translational research: a technical overview. Yale J Biol Med. 2012 Mar; 85(1):59-73. PMID: 22461744.
    Citations: 7     Fields:    Translation:HumansAnimals
  168. Paulo JA, Lee LS, Banks PA, Steen H, Conwell DL. Proteomic analysis of formalin-fixed paraffin-embedded pancreatic tissue using liquid chromatography tandem mass spectrometry. Pancreas. 2012 Mar; 41(2):175-85. PMID: 22015969.
    Citations: 13     Fields:    Translation:Humans
  169. Paulo JA, Kadiyala V, Lee LS, Banks PA, Conwell DL, Steen H. Proteomic analysis (GeLC-MS/MS) of ePFT-collected pancreatic fluid in chronic pancreatitis. J Proteome Res. 2012 Mar 02; 11(3):1897-912. PMID: 22243521.
    Citations: 17     Fields:    Translation:Humans
  170. Broadbelt KG, Rivera KD, Paterson DS, Duncan JR, Trachtenberg FL, Paulo JA, Stapels MD, Borenstein NS, Belliveau RA, Haas EA, Stanley C, Krous HF, Steen H, Kinney HC. Brainstem deficiency of the 14-3-3 regulator of serotonin synthesis: a proteomics analysis in the sudden infant death syndrome. Mol Cell Proteomics. 2012 Jan; 11(1):M111.009530. PMID: 21976671.
    Citations: 20     Fields:    Translation:Humans
  171. Paulo JA, Urrutia R, Banks PA, Conwell DL, Steen H. Proteomic analysis of a rat pancreatic stellate cell line using liquid chromatography tandem mass spectrometry (LC-MS/MS). J Proteomics. 2011 Dec 21; 75(2):708-17. PMID: 21968429.
    Citations: 18     Fields:    Translation:AnimalsCells
  172. Paulo JA, Urrutia R, Banks PA, Conwell DL, Steen H. Proteomic analysis of an immortalized mouse pancreatic stellate cell line identifies differentially-expressed proteins in activated vs nonproliferating cell states. J Proteome Res. 2011 Oct 07; 10(10):4835-44. PMID: 21838295.
    Citations: 22     Fields:    Translation:AnimalsCells
  173. Lysaght AC, Kao SY, Paulo JA, Merchant SN, Steen H, Stankovic KM. Proteome of human perilymph. J Proteome Res. 2011 Sep 02; 10(9):3845-51. PMID: 21740021.
    Citations: 20     Fields:    Translation:Humans
  174. Paulo JA, Lee LS, Banks PA, Steen H, Conwell DL. Difference gel electrophoresis identifies differentially expressed proteins in endoscopically collected pancreatic fluid. Electrophoresis. 2011 Aug; 32(15):1939-51. PMID: 21792986.
    Citations: 5     Fields:    Translation:Humans
  175. Paulo JA, Lee LS, Wu B, Banks PA, Steen H, Conwell DL. Cytokine profiling of pancreatic fluid using the ePFT collection method in tandem with a multiplexed microarray assay. J Immunol Methods. 2011 Jun 30; 369(1-2):98-107. PMID: 21569776.
    Citations: 11     Fields:    Translation:Humans
  176. Paulo JA, Lee LS, Wu B, Banks PA, Steen H, Conwell DL. Mass spectrometry-based proteomics of endoscopically collected pancreatic fluid in chronic pancreatitis research. Proteomics Clin Appl. 2011 Apr; 5(3-4):109-20. PMID: 21360826.
    Citations: 11     Fields:    Translation:Humans
  177. Paulo JA, Lee LS, Wu B, Repas K, Banks PA, Conwell DL, Steen H. Proteomic analysis of endoscopically (endoscopic pancreatic function test) collected gastroduodenal fluid using in-gel tryptic digestion followed by LC-MS/MS. Proteomics Clin Appl. 2010 Sep; 4(8-9):715-25. PMID: 21137089.
    Citations: 14     Fields:    Translation:Humans
  178. Paulo JA, Lee LS, Wu B, Repas K, Mortele KJ, Banks PA, Steen H, Conwell DL. Identification of pancreas-specific proteins in endoscopically (endoscopic pancreatic function test) collected pancreatic fluid with liquid chromatography--tandem mass spectrometry. Pancreas. 2010 Aug; 39(6):889-96. PMID: 20182389.
    Citations: 18     Fields:    Translation:Humans
  179. Paulo JA, Lee LS, Wu B, Repas K, Banks PA, Conwell DL, Steen H. Optimized sample preparation of endoscopic collected pancreatic fluid for SDS-PAGE analysis. Electrophoresis. 2010 Jul; 31(14):2377-87. PMID: 20589857.
    Citations: 16     Fields:    Translation:HumansCells
  180. Paulo JA, Hawrot E. Effect of homologous serotonin receptor loop substitutions on the heterologous expression in Pichia of a chimeric acetylcholine-binding protein with alpha-bungarotoxin-binding activity. Protein Expr Purif. 2009 Oct; 67(2):76-81. PMID: 19427904.
    Citations: 2     Fields:    Translation:AnimalsCells
  181. Paulo JA, Brucker WJ, Hawrot E. Proteomic analysis of an alpha7 nicotinic acetylcholine receptor interactome. J Proteome Res. 2009 Apr; 8(4):1849-58. PMID: 19714875.
    Citations: 44     Fields:    Translation:AnimalsCells
  182. Paulo JA, Hawrot E. A radioisotope label-free alpha-bungarotoxin-binding assay using BIAcore sensor chip technology for real-time analysis. Anal Biochem. 2009 Jun 01; 389(1):86-8. PMID: 19289092.
    Citations: 1     Fields: