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Jatin Mahesh Vyas, M.D., Ph.D.

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1985 - 1989
Welch Foundation Scholar in Chemistry
Internship, Michael E. DeBakey, MD summer student program
Introduction to Biomedical Research Participant
1988 - 1989
Alpha Epsilon Delta Honor Society
Goodfellows Award
1989 - 1996
Medical Scientist Training Program Fellow
1990 - 1994
MSTP Medical School Admission Committee Member
1992 - 1993
Arthritis Foundation Medical Student Grant
Medical Student Award
Invited Platform Speaker for the Sixth Annual Graduate Student Research Symposium
Oral Presentation at the XIV Annual Convention
Sigma Xi Dissertation Excellence Award, Honorable Mention
2000 - 2001
Chief Resident in Internal Medicine
Kass Award for Clinical Excellence in Infectious Diseases
IDSA Travel Grant for Outstanding Abstract
Partners in Excellence for Outstanding Service to the Department of Medicine
Travel award for outstanding abstract

My research interests focus on the immune responses to fungal pathogens. Charged with the responsibility to protect a host from pathogenic microorganisms, the immune system detects, neutralizes, and eliminates these invaders using many different specialized cells. One arm of the immune system deploys sentinels throughout the body. Their purpose is two-fold. First, professional antigen presenting cells (APCs) capture invading pathogens by phagocytosis and degrade them before they cause additional harm to the host. Second, APCs must “deliver the message” about the presence of pathogens in the periphery to T cells located in regional lymph nodes in order to amplify the immune response. How does an APC talk to the T cell? Both cells come together and form a cell-cell synapse whereby the T cell interrogates the surface of the APC for the presence of a pathogen-specific signal that, when present, activates the T cell. Specialized immune proteins, termed class II MHC molecules, are heterodimeric protein complexes that present this signal. Dendritic cells (DCs) are potent professional APCs that express abundant class II MHC molecules and possess the unique capacity to activate naïve T cells. In order to serve as an effective APC, newly-captured pathogens must be shuttled to the endolysosomes for degradation. To accomplish this task, APCs place pathogens into membrane-delimited compartments termed phagosomes. These compartments undergo a series of membrane modifications, drop their pH and activate proteases which facilitate degradation of the cargo. The biomolecular mechanism of phagosome maturation is incompletely understood including the identity and kinetics of association and dissociation of most proteins on phagosomal membranes. When properly folded, class II MHC molecules form a pocket for pathogen-derived peptides (protein fragments). In the endolysosome, a specialized compartment within the APC, class II MHC molecules associate with pathogen-derived peptides and traffic from intracellular compartments to the cell surface. Antigen presentation requires the coordinated efforts of multiple host proteins including members of the tetraspanin superfamily, though their exact function in this process remains poorly understood.
When the process of antigen processing and presentation works well, the host is protected from a number of virulent microorganisms. Failure of an effective immune response, however, can lead to overwhelming infection and possibly death. This failure is caused typically by specific cellular defects in the immune system as seen in HIV infection, older age, or administration of immunosuppressive medications. My major goal is to understand the rules that govern the fate of fungal pathogens including Aspergillus fumigatus, Candida albicans and Cryptococcus neoformans upon phagocytosis by real-time visualization of professional APCs expressing fluorescently-tagged proteins relevant to antigen processing and presentation using spinning-disk confocal microscopy.

I also serve as the tenth Program Director for the Massachusetts General Hospital Department of Medicine. I oversee the educational activities for the interns and residents. The MGH Internal Medicine Residency program has a long and world-renowned tradition of training leaders in academic medicine and biomedical science. The foundation of our program is rigorous clinical training that emphasizes clinical excellence, teamwork, leadership and career development. Our dedicated teaching faculty, resident research opportunities and experiences in international health and the local community ensure that our residents become outstanding physicians.

We enjoy strong house staff camaraderie and a supportive community in which diversity is celebrated. We take pride in training leaders in clinical and basic research, clinical practice, education, health policy, global health, administration and others. The outstanding achievements of our graduates remain the strongest affirmation of the goals of the training program

The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. R38HL150212 (VYAS, JATIN M) Jul 1, 2020 - Jun 30, 2024
    MGH Next Generation Physician-Scientist Through Stimulating Access to Research in Residency Program (MGH-Next Gen StARR)
    Role: Principal Investigator
  2. R01AI150181 (VYAS, JATIN M) Apr 10, 2020 - Mar 31, 2025
    Control of Type I Interferon Production in Response to Candida albicans
    Role: Principal Investigator
  3. R25AI147393 (VYAS, JATIN M) Aug 12, 2019 - Jul 31, 2024
    Pathways to Mentorship and Research: Training the Next Generation Physician-Scientists
    Role: Principal Investigator
  4. R01AI136529 (VYAS, JATIN M) Jan 11, 2018 - Dec 31, 2022
    The Functional Role of the Tetraspanin CD82/Kai1 in Fungal Innate Immunity
    Role: Principal Investigator
  5. R21AI109303 (VYAS, JATIN M) Jul 1, 2015 - Jun 30, 2017
    Systems Analysis of Innate Immune Responses to Fungal-Derived Carbohydrates
    Role: Principal Investigator

Featured Content

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Boucau J, Uddin R, Marino C, Regan J, Flynn JP, Choudhary MC, Chen G, Stuckwisch AM, Mathews J, Liew MY, Singh A, Reynolds Z, Iyer SL, Chamberlin GC, Vyas TD, Vyas JM, Turbett SE, Li JZ, Lemieux JE, Barczak AK, Siedner MJ. Characterization of Virologic Rebound Following Nirmatrelvir-Ritonavir Treatment for Coronavirus Disease 2019 (COVID-19). Clin Infect Dis. 2023 02 08; 76(3):e526-e529. PMID: 35737946; PMCID: PMC9384370.
    Citations: 3     Fields:    
  2. Zhang Y, Lin T, Leung HM, Zhang C, Wilson-Mifsud B, Feldman MB, Puel A, Lanternier F, Couderc LJ, Danion F, Catherinot E, Salvator H, Tcherkian C, Givel C, Xu J, Tearney GJ, Vyas JM, Li H, Hurley BP, Mou H. STAT3 mutation-associated airway epithelial defects in Job syndrome. J Allergy Clin Immunol. 2023 Jan 10. PMID: 36638921.
    Citations:    Fields:    
  3. Reedy JL, Crossen AJ, Negoro PE, Harding HB, Ward RA, Vargas-Blanco DA, Timmer KD, Reardon CM, Basham KJ, Mansour MK, Wüthrich M, Fontaine T, Latgé JP, Vyas JM. The C-Type Lectin Receptor Dectin-2 Is a Receptor for Aspergillus fumigatus Galactomannan. mBio. 2023 Feb 28; 14(1):e0318422. PMID: 36598192; PMCID: PMC9973300.
    Citations:    Fields:    
  4. Crossen AJ, Ward RA, Reedy JL, Surve MV, Klein BS, Rajagopal J, Vyas JM. Human Airway Epithelium Responses to Invasive Fungal Infections: A Critical Partner in Innate Immunity. J Fungi (Basel). 2022 Dec 27; 9(1). PMID: 36675861; PMCID: PMC9862202.
  5. Seaman MS, Siedner MJ, Boucau J, Lavine CL, Ghantous F, Liew MY, Mathews JI, Singh A, Marino C, Regan J, Uddin R, Choudhary MC, Flynn JP, Chen G, Stuckwisch AM, Lipiner T, Kittilson A, Melberg M, Gilbert RF, Reynolds Z, Iyer SL, Chamberlin GC, Vyas TD, Vyas JM, Goldberg MB, Luban J, Li JZ, Barczak AK, Lemieux JE. Vaccine breakthrough infection leads to distinct profiles of neutralizing antibody responses by SARS-CoV-2 variant. JCI Insight. 2022 10 10; 7(19). PMID: 36214224; PMCID: PMC9675445.
    Citations: 5     Fields:    Translation:HumansCells
  6. Bromberg GK, Simpkin Begin A, Salik JR, Vyas JM. Digital Small Talk: Residency Community Building in a Virtual World. Acad Med. 2022 Sep 27. PMID: 36525398.
    Citations:    Fields:    
  7. Boucau J, Marino C, Regan J, Uddin R, Choudhary MC, Flynn JP, Chen G, Stuckwisch AM, Mathews J, Liew MY, Singh A, Lipiner T, Kittilson A, Melberg M, Li Y, Gilbert RF, Reynolds Z, Iyer SL, Chamberlin GC, Vyas TD, Goldberg MB, Vyas JM, Li JZ, Lemieux JE, Siedner MJ, Barczak AK. Duration of Shedding of Culturable Virus in SARS-CoV-2 Omicron (BA.1) Infection. N Engl J Med. 2022 07 21; 387(3):275-277. PMID: 35767428; PMCID: PMC9258747.
    Citations: 1     Fields:    Translation:HumansAnimalsCells
  8. Thakar A, Panara K, Shah H, Kalsariya B, Ruparel S, Jain N, Bhatt P, Jani D, Dodia R, Patel F, Salve R, Chaudhari S, Raghavani H, Vyas J, Goyal M, Bhinde S. Guduchi Ghanavati (Ayurveda medication) improves the perceived immunity in individuals at risk of SARS-CoV-2: A Multicentred, controlled, before-and-after study. Eur J Integr Med. 2022 Aug; 53:102131. PMID: 35506012; PMCID: PMC9047434.
  9. North CM, Barczak A, Goldstein RH, Healy BC, Finkelstein DM, Ding DD, Kim A, Boucau J, Shaw B, Gilbert RF, Vyas T, Reynolds Z, Siddle KJ, MacInnis BL, Regan J, Flynn JP, Choudhary MC, Vyas JM, Laskowski K, Dighe AS, Lemieux JE, Li JZ, Baden LR, Siedner MJ, Woolley AE, Sacks CA. Determining the Incidence of Asymptomatic SARS-CoV-2 Among Early Recipients of COVID-19 Vaccines (DISCOVER-COVID-19): A Prospective Cohort Study of Healthcare Workers Before, During and After Vaccination. Clin Infect Dis. 2022 04 09; 74(7):1275-1278. PMID: 34363462; PMCID: PMC8436402.
    Citations: 8     Fields:    Translation:HumansCellsPHPublic Health
  10. Vyas JM, Castle AC, Bourgouin PP, Turbett SE. Case 9-2022: A 56-Year-Old Woman with Fever, Myalgias, Diarrhea, and Cough. N Engl J Med. 2022 Mar 24; 386(12):1166-1174. PMID: 35320647.
    Citations:    Fields:    Translation:HumansCells
  11. Gallagher EJ, Rockey DC, Kontos CD, Vyas JM, Brass LF, Hu PJ, Isales CM, Ajijola OA, Rathmell WK, Conlin PR, Baiocchi RA, Kazmierczak BI, Akabas MH, Williams CS. Pearls of wisdom for aspiring physician-scientist residency applicants and program directors. JCI Insight. 2022 03 22; 7(6). PMID: 35315364; PMCID: PMC8986063.
    Citations:    Fields:    Translation:Humans
  12. Seaman MS, Siedner MJ, Boucau J, Lavine CL, Ghantous F, Liew MY, Mathews J, Singh A, Marino C, Regan J, Uddin R, Choudhary MC, Flynn JP, Chen G, Stuckwisch AM, Lipiner T, Kittilson A, Melberg M, Gilbert RF, Reynolds Z, Iyer SL, Chamberlin GC, Vyas TD, Vyas JM, Goldberg MB, Luban J, Li JZ, Barczak AK, Lemieux JE. Vaccine Breakthrough Infection with the SARS-CoV-2 Delta or Omicron (BA.1) Variant Leads to Distinct Profiles of Neutralizing Antibody Responses. medRxiv. 2022 Mar 03. PMID: 35262094; PMCID: PMC8902886.
    Citations: 1     
  13. Boucau J, Marino C, Regan J, Uddin R, Choudhary MC, Flynn JP, Chen G, Stuckwisch AM, Mathews J, Liew MY, Singh A, Lipiner T, Kittilson A, Melberg M, Li Y, Gilbert RF, Reynolds Z, Iyer SL, Chamberlin GC, Vyas TD, Goldberg MB, Vyas JM, Li JZ, Lemieux JE, Siedner MJ, Barczak AK. Duration of viable virus shedding in SARS-CoV-2 omicron variant infection. medRxiv. 2022 Mar 02. PMID: 35262089; PMCID: PMC8902872.
  14. Siedner MJ, Boucau J, Gilbert RF, Uddin R, Luu J, Haneuse S, Vyas T, Reynolds Z, Iyer S, Chamberlin GC, Goldstein RH, North CM, Sacks CA, Regan J, Flynn JP, Choudhary MC, Vyas JM, Barczak AK, Lemieux JE, Li JZ. Duration of viral shedding and culture positivity with postvaccination SARS-CoV-2 delta variant infections. JCI Insight. 2022 01 25; 7(2). PMID: 34871181; PMCID: PMC8855795.
    Citations: 10     Fields:    Translation:HumansCells
  15. Truong-Bolduc QC, Wang Y, Reedy JL, Vyas JM, Hooper DC. Staphylococcus aureus Efflux Pumps and Tolerance to Ciprofloxacin and Chlorhexidine following Induction by Mupirocin. Antimicrob Agents Chemother. 2022 02 15; 66(2):e0184521. PMID: 34930023; PMCID: PMC8846467.
    Citations: 2     Fields:    Translation:Cells
  16. Ward RA, Aghaeepour N, Bhattacharyya RP, Clish CB, Gaudillière B, Hacohen N, Mansour MK, Mudd PA, Pasupneti S, Presti RM, Rhee EP, Sen P, Spec A, Tam JM, Villani AC, Woolley AE, Hsu JL, Vyas JM. Harnessing the Potential of Multiomics Studies for Precision Medicine in Infectious Disease. Open Forum Infect Dis. 2021 Nov; 8(11):ofab483. PMID: 34805429; PMCID: PMC8598922.
  17. Ward RA, Thompson GR, Villani AC, Li B, Mansour MK, Wuethrich M, Tam JM, Klein BS, Vyas JM. The Known Unknowns of the Immune Response to Coccidioides. J Fungi (Basel). 2021 May 11; 7(5). PMID: 34065016; PMCID: PMC8151481.
    Citations: 1     
  18. Ward RA, Vyas JM. The first line of defense: effector pathways of anti-fungal innate immunity. Curr Opin Microbiol. 2020 12; 58:160-165. PMID: 33217703.
    Citations: 6     Fields:    Translation:HumansAnimalsCells
  19. Charles RC, Kelly M, Tam JM, Akter A, Hossain M, Islam K, Biswas R, Kamruzzaman M, Chowdhury F, Khan AI, Leung DT, Weil A, LaRocque RC, Bhuiyan TR, Rahman A, Mayo-Smith LM, Becker RL, Vyas JM, Faherty CS, Nickerson KP, Giffen S, Ritter AS, Waldor MK, Xu P, Kovác P, Calderwood SB, Kauffman RC, Wrammert J, Qadri F, Harris JB, Ryan ET. Humans Surviving Cholera Develop Antibodies against Vibrio cholerae O-Specific Polysaccharide That Inhibit Pathogen Motility. mBio. 2020 11 17; 11(6). PMID: 33203761; PMCID: PMC7683404.
    Citations: 9     Fields:    Translation:HumansAnimalsCells
  20. Negoro PE, Xu S, Dagher Z, Hopke A, Reedy JL, Feldman MB, Khan NS, Viens AL, Alexander NJ, Atallah NJ, Scherer AK, Dutko RA, Jeffery J, Kernien JF, Fites JS, Nett JE, Klein BS, Vyas JM, Irimia D, Sykes DB, Mansour MK. Spleen Tyrosine Kinase Is a Critical Regulator of Neutrophil Responses to Candida Species. mBio. 2020 05 12; 11(3). PMID: 32398316; PMCID: PMC7218286.
    Citations: 12     Fields:    Translation:AnimalsCells
  21. Dover JS, Moran ML, Figueroa JF, Furnas H, Vyas JM, Wiviott LD, Karchmer AW. A Path to Resume Aesthetic Care: Executive Summary of Project AesCert Guidance Supplement-Practical Considerations for Aesthetic Medicine Professionals Supporting Clinic Preparedness in Response to the SARS-CoV-2 Outbreak. Facial Plast Surg Aesthet Med. 2020 May/Jun; 22(3):125-151. PMID: 32374192.
    Citations: 3     Fields:    Translation:HumansPHPublic Health
    Citations: 1     Fields:    
  23. Wiesner DL, Merkhofer RM, Ober C, Kujoth GC, Niu M, Keller NP, Gern JE, Brockman-Schneider RA, Evans MD, Jackson DJ, Warner T, Jarjour NN, Esnault SJ, Feldman MB, Freeman M, Mou H, Vyas JM, Klein BS. Club Cell TRPV4 Serves as a Damage Sensor Driving Lung Allergic Inflammation. Cell Host Microbe. 2020 04 08; 27(4):614-628.e6. PMID: 32130954; PMCID: PMC7305569.
    Citations: 13     Fields:    Translation:HumansAnimalsCells
  24. Permar SR, Ward RA, Barrett KJ, Freel SA, Gbadegesin RA, Kontos CD, Hu PJ, Hartmann KE, Williams CS, Vyas JM. Addressing the physician-scientist pipeline: strategies to integrate research into clinical training programs. J Clin Invest. 2020 03 02; 130(3):1058-1061. PMID: 32039914; PMCID: PMC7269558.
    Citations: 3     Fields:    Translation:Humans
  25. Feldman MB, Dutko RA, Wood MA, Ward RA, Leung HM, Snow RF, De La Flor DJ, Yonker LM, Reedy JL, Tearney GJ, Mou H, Hurley BP, Vyas JM. Aspergillus fumigatus Cell Wall Promotes Apical Airway Epithelial Recruitment of Human Neutrophils. Infect Immun. 2020 01 22; 88(2). PMID: 31767773; PMCID: PMC6977131.
    Citations: 5     Fields:    Translation:HumansAnimalsCells
  26. Bonilla A, Blair AJ, Alamro SM, Ward RA, Feldman MB, Dutko RA, Karagounis TK, Johnson AL, Folch EE, Vyas JM. Recurrent spontaneous pneumothoraces and vaping in an 18-year-old man: a case report and review of the literature. J Med Case Rep. 2019 Sep 09; 13(1):283. PMID: 31495337.
    Citations: 14     Fields:    Translation:Humans
  27. Khan NS, Lukason DP, Feliu M, Ward RA, Lord AK, Reedy JL, Ramirez-Ortiz ZG, Tam JM, Kasperkovitz PV, Negoro PE, Vyas TD, Xu S, Brinkmann MM, Acharaya M, Artavanis-Tsakonas K, Frickel EM, Becker CE, Dagher Z, Kim YM, Latz E, Ploegh HL, Mansour MK, Miranti CK, Levitz SM, Vyas JM. CD82 controls CpG-dependent TLR9 signaling. FASEB J. 2019 11; 33(11):12500-12514. PMID: 31408613; PMCID: PMC6988855.
    Citations: 6     Fields:    Translation:AnimalsCells
  28. Asghar W, Sher M, Khan NS, Vyas JM, Demirci U. Microfluidic Chip for Detection of Fungal Infections. ACS Omega. 2019 Apr 30; 4(4):7474-7481. PMID: 31080939; PMCID: PMC6504191.
    Citations: 13     
  29. Tam JM, Reedy JL, Lukason DP, Kuna SG, Acharya M, Khan NS, Negoro PE, Xu S, Ward RA, Feldman MB, Dutko RA, Jeffery JB, Sokolovska A, Wivagg CN, Lassen KG, Le Naour F, Matzaraki V, Garner EC, Xavier RJ, Kumar V, van de Veerdonk FL, Netea MG, Miranti CK, Mansour MK, Vyas JM. Tetraspanin CD82 Organizes Dectin-1 into Signaling Domains to Mediate Cellular Responses to Candida albicans. J Immunol. 2019 06 01; 202(11):3256-3266. PMID: 31010852; PMCID: PMC6529278.
    Citations: 10     Fields:    Translation:HumansAnimalsCells
  30. Jones CN, Ellett F, Robertson AL, Forrest KM, Judice K, Balkovec JM, Springer M, Markmann JF, Vyas JM, Warren HS, Irimia D. Bifunctional Small Molecules Enhance Neutrophil Activities Against Aspergillus fumigatus in vivo and in vitro. Front Immunol. 2019; 10:644. PMID: 31024528.
    Citations: 7     Fields:    Translation:HumansAnimalsCells
  31. Williams CS, Iness AN, Baron RM, Ajijola OA, Hu PJ, Vyas JM, Baiocchi R, Adami AJ, Lever JM, Klein PS, Demer L, Madaio M, Geraci M, Brass LF, Blanchard M, Salata R, Zaidi M. Training the physician-scientist: views from program directors and aspiring young investigators. JCI Insight. 2018 12 06; 3(23). PMID: 30518696; PMCID: PMC6328016.
    Citations: 16     Fields:    Translation:Humans
  32. Singh U, Levy J, Armstrong W, Bedimo R, Creech CB, Lautenbach E, Popovich KJ, Snowden J, Vyas JM. Policy Recommendations for Optimizing the Infectious Diseases Physician-Scientist Workforce. J Infect Dis. 2018 08 14; 218(suppl_1):S49-S54. PMID: 30124981.
    Citations: 7     Fields:    Translation:Humans
  33. Vyas JM, Rajagopal J, Sokol CL, Wein MN, Mansour MK, Corey KE, Fishman MC, Armstrong KA. The Great Opportunity: Cultivating Scientific Inquiry in Medical Residency. J Infect Dis. 2018 08 14; 218(suppl_1):S44-S48. PMID: 29878132; PMCID: PMC6093444.
    Citations: 1     Fields:    Translation:Humans
  34. Feldman MB, Vyas JM, Mansour MK. It takes a village: Phagocytes play a central role in fungal immunity. Semin Cell Dev Biol. 2019 05; 89:16-23. PMID: 29727727; PMCID: PMC6235731.
    Citations: 4     Fields:    Translation:HumansAnimalsCells
  35. Marshall AL, Jenkins S, Oxentenko AS, Lee AI, Siegel MD, Katz JT, Vyas JM, Del Valle J, Mikhael JR. Internal medicine trainees' knowledge and confidence in using the American Society of Hematology Choosing Wisely guidelines in hemostasis, thrombosis, and non-malignant hematology. PLoS One. 2018; 13(5):e0197414. PMID: 29768480.
    Citations: 1     Fields:    Translation:Humans
  36. Simpkin AL, Vyas JM, Armstrong KA. Diagnostic Reasoning. Ann Intern Med. 2018 05 15; 168(10):751-752. PMID: 29800439.
    Citations:    Fields:    
  37. Li SS, Ogbomo H, Mansour MK, Xiang RF, Szabo L, Munro F, Mukherjee P, Mariuzza RA, Amrein M, Vyas JM, Robbins SM, Mody CH. Identification of the fungal ligand triggering cytotoxic PRR-mediated NK cell killing of Cryptococcus and Candida. Nat Commun. 2018 02 21; 9(1):751. PMID: 29467448.
    Citations: 25     Fields:    Translation:HumansAnimalsCells
  38. Simpkin AL, Vyas JM, Armstrong KA. Diagnostic Reasoning: An Endangered Competency in Internal Medicine Training. Ann Intern Med. 2017 Oct 03; 167(7):507-508. PMID: 28892818.
    Citations: 5     Fields:    Translation:Humans
  39. Reedy JL, Negoro PE, Feliu M, Lord AK, Khan NS, Lukason DP, Wiederhold NP, Tam JM, Mansour MK, Patterson TF, Vyas JM. The Carbohydrate Lectin Receptor Dectin-1 Mediates the Immune Response to Exserohilum rostratum. Infect Immun. 2017 03; 85(3). PMID: 28031265; PMCID: PMC5328484.
    Citations: 8     Fields:    Translation:HumansAnimalsCells
  40. Truong-Bolduc QC, Khan NS, Vyas JM, Hooper DC. Tet38 Efflux Pump Affects Staphylococcus aureus Internalization by Epithelial Cells through Interaction with CD36 and Contributes to Bacterial Escape from Acidic and Nonacidic Phagolysosomes. Infect Immun. 2017 02; 85(2). PMID: 27956597; PMCID: PMC5278174.
    Citations: 11     Fields:    Translation:HumansCells
  41. McCluskey SM, Schuetz P, Abers MS, Bearnot B, Morales ME, Hoffman D, Patel S, Rosario L, Chiappa V, Parry BA, Callahan RT, Bond SA, Lewandrowski K, Binder W, Filbin MR, Vyas JM, Mansour MK. Serial Procalcitonin as a Predictor of Bacteremia and Need for Intensive Care Unit Care in Adults With Pneumonia, Including Those With Highest Severity: A Prospective Cohort Study. Open Forum Infect Dis. 2017; 4(1):ofw238. PMID: 28480236; PMCID: PMC5414101.
    Citations: 3     
  42. Schlimgen R, Howard J, Wooley D, Thompson M, Baden LR, Yang OO, Christiani DC, Mostoslavsky G, Diamond DV, Duane EG, Byers K, Winters T, Gelfand JA, Fujimoto G, Hudson TW, Vyas JM. Risks Associated With Lentiviral Vector Exposures and Prevention Strategies. J Occup Environ Med. 2016 12; 58(12):1159-1166. PMID: 27930472; PMCID: PMC5152689.
    Citations: 27     Fields:    Translation:HumansCellsPHPublic Health
  43. Safavieh M, Coarsey C, Esiobu N, Memic A, Vyas JM, Shafiee H, Asghar W. Advances in Candida detection platforms for clinical and point-of-care applications. Crit Rev Biotechnol. 2017 Jun; 37(4):441-458. PMID: 27093473; PMCID: PMC5083221.
    Citations: 17     Fields:    Translation:HumansAnimals
  44. Tam JM, Mansour MK, Acharya M, Sokolovska A, Timmons AK, Lacy-Hulbert A, Vyas JM. The Role of Autophagy-Related Proteins in Candida albicans Infections. Pathogens. 2016 Mar 29; 5(2). PMID: 27043636; PMCID: PMC4931385.
    Citations: 6     
  45. Acharya M, Sokolovska A, Tam JM, Conway KL, Stefani C, Raso F, Mukhopadhyay S, Feliu M, Paul E, Savill J, Hynes RO, Xavier RJ, Vyas JM, Stuart LM, Lacy-Hulbert A. av Integrins combine with LC3 and atg5 to regulate Toll-like receptor signalling in B cells. Nat Commun. 2016 Mar 11; 7:10917. PMID: 26965188; PMCID: PMC4792966.
    Citations: 23     Fields:    Translation:AnimalsCells
  46. Li X, Cullere X, Nishi H, Saggu G, Durand E, Mansour MK, Tam JM, Song XY, Lin X, Vyas JM, Mayadas T. PKC-d activation in neutrophils promotes fungal clearance. J Leukoc Biol. 2016 09; 100(3):581-8. PMID: 26965632; PMCID: PMC6608027.
    Citations: 11     Fields:    Translation:AnimalsCells
  47. Terry AR, Kahle KT, Larvie M, Vyas JM, Stemmer-Rachamimov A. CASE RECORDS of the MASSACHUSETTS GENERAL HOSPITAL. Case 5-2016. A 43-Year-Old Man with Altered Mental Status and a History of Alcohol Use. N Engl J Med. 2016 Feb 18; 374(7):671-80. PMID: 26886525.
    Citations: 5     Fields:    Translation:HumansAnimals
  48. Abers MS, Ghebremichael MS, Timmons AK, Warren HS, Poznansky MC, Vyas JM. A Critical Reappraisal of Prolonged Neutropenia as a Risk Factor for Invasive Pulmonary Aspergillosis. Open Forum Infect Dis. 2016 Jan; 3(1):ofw036. PMID: 27006961; PMCID: PMC4800458.
    Citations: 7     
  49. Khan NS, Kasperkovitz PV, Timmons AK, Mansour MK, Tam JM, Seward MW, Reedy JL, Puranam S, Feliu M, Vyas JM. Dectin-1 Controls TLR9 Trafficking to Phagosomes Containing ß-1,3 Glucan. J Immunol. 2016 Mar 01; 196(5):2249-61. PMID: 26829985; PMCID: PMC4761466.
    Citations: 21     Fields:    Translation:HumansAnimalsCells
  50. Klionsky DJ, Abdelmohsen K, Abe A, Abedin MJ, Abeliovich H, Acevedo Arozena A, Adachi H, Adams CM, Adams PD, Adeli K, Adhihetty PJ, Adler SG, Agam G, Agarwal R, Aghi MK, Agnello M, Agostinis P, Aguilar PV, Aguirre-Ghiso J, Airoldi EM, Ait-Si-Ali S, Akematsu T, Akporiaye ET, Al-Rubeai M, Albaiceta GM, Albanese C, Albani D, Albert ML, Aldudo J, Algül H, Alirezaei M, Alloza I, Almasan A, Almonte-Beceril M, Alnemri ES, Alonso C, Altan-Bonnet N, Altieri DC, Alvarez S, Alvarez-Erviti L, Alves S, Amadoro G, Amano A, Amantini C, Ambrosio S, Amelio I, Amer AO, Amessou M, Amon A, An Z, Anania FA, Andersen SU, Andley UP, Andreadi CK, Andrieu-Abadie N, Anel A, Ann DK, Anoopkumar-Dukie S, Antonioli M, Aoki H, Apostolova N, Aquila S, Aquilano K, Araki K, Arama E, Aranda A, Araya J, Arcaro A, Arias E, Arimoto H, Ariosa AR, Armstrong JL, Arnould T, Arsov I, Asanuma K, Askanas V, Asselin E, Atarashi R, Atherton SS, Atkin JD, Attardi LD, Auberger P, Auburger G, Aurelian L, Autelli R, Avagliano L, Avantaggiati ML, Avrahami L, Awale S, Azad N, Bachetti T, Backer JM, Bae DH, Bae JS, Bae ON, Bae SH, Baehrecke EH, Baek SH, Baghdiguian S, Bagniewska-Zadworna A, Bai H, Bai J, Bai XY, Bailly Y, Balaji KN, Balduini W, Ballabio A, Balzan R, Banerjee R, Bánhegyi G, Bao H, Barbeau B, Barrachina MD, Barreiro E, Bartel B, Bartolomé A, Bassham DC, Bassi MT, Bast RC, Basu A, Batista MT, Batoko H, Battino M, Bauckman K, Baumgarner BL, Bayer KU, Beale R, Beaulieu JF, Beck GR, Becker C, Beckham JD, Bédard PA, Bednarski PJ, Begley TJ, Behl C, Behrends C, Behrens GM, Behrns KE, Bejarano E, Belaid A, Belleudi F, Bénard G, Berchem G, Bergamaschi D, Bergami M, Berkhout B, Berliocchi L, Bernard A, Bernard M, Bernassola F, Bertolotti A, Bess AS, Besteiro S, Bettuzzi S, Bhalla S, Bhattacharyya S, Bhutia SK, Biagosch C, Bianchi MW, Biard-Piechaczyk M, Billes V, Bincoletto C, Bingol B, Bird SW, Bitoun M, Bjedov I, Blackstone C, Blanc L, Blanco GA, Blomhoff HK, Boada-Romero E, Böckler S, Boes M, Boesze-Battaglia K, Boise LH, Bolino A, Boman A, Bonaldo P, Bordi M, Bosch J, Botana LM, Botti J, Bou G, Bouché M, Bouchecareilh M, Boucher MJ, Boulton ME, Bouret SG, Boya P, Boyer-Guittaut M, Bozhkov PV, Brady N, Braga VM, Brancolini C, Braus GH, Bravo-San Pedro JM, Brennan LA, Bresnick EH, Brest P, Bridges D, Bringer MA, Brini M, Brito GC, Brodin B, Brookes PS, Brown EJ, Brown K, Broxmeyer HE, Bruhat A, Brum PC, Brumell JH, Brunetti-Pierri N, Bryson-Richardson RJ, Buch S, Buchan AM, Budak H, Bulavin DV, Bultman SJ, Bultynck G, Bumbasirevic V, Burelle Y, Burke RE, Burmeister M, Bütikofer P, Caberlotto L, Cadwell K, Cahova M, Cai D, Cai J, Cai Q, Calatayud S, Camougrand N, Campanella M, Campbell GR, Campbell M, Campello S, Candau R, Caniggia I, Cantoni L, Cao L, Caplan AB, Caraglia M, Cardinali C, Cardoso SM, Carew JS, Carleton LA, Carlin CR, Carloni S, Carlsson SR, Carmona-Gutierrez D, Carneiro LA, Carnevali O, Carra S, Carrier A, Carroll B, Casas C, Casas J, Cassinelli G, Castets P, Castro-Obregon S, Cavallini G, Ceccherini I, Cecconi F, Cederbaum AI, Ceña V, Cenci S, Cerella C, Cervia D, Cetrullo S, Chaachouay H, Chae HJ, Chagin AS, Chai CY, Chakrabarti G, Chamilos G, Chan EY, Chan MT, Chandra D, Chandra P, Chang CP, Chang RC, Chang TY, Chatham JC, Chatterjee S, Chauhan S, Che Y, Cheetham ME, Cheluvappa R, Chen CJ, Chen G, Chen GC, Chen G, Chen H, Chen JW, Chen JK, Chen M, Chen M, Chen P, Chen Q, Chen Q, Chen SD, Chen S, Chen SS, Chen W, Chen WJ, Chen WQ, Chen W, Chen X, Chen YH, Chen YG, Chen Y, Chen Y, Chen Y, Chen YJ, Chen YQ, Chen Y, Chen Z, Chen Z, Cheng A, Cheng CH, Cheng H, Cheong H, Cherry S, Chesney J, Cheung CH, Chevet E, Chi HC, Chi SG, Chiacchiera F, Chiang HL, Chiarelli R, Chiariello M, Chieppa M, Chin LS, Chiong M, Chiu GN, Cho DH, Cho SG, Cho WC, Cho YY, Cho YS, Choi AM, Choi EJ, Choi EK, Choi J, Choi ME, Choi SI, Chou TF, Chouaib S, Choubey D, Choubey V, Chow KC, Chowdhury K, et al. Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). Autophagy. 2016; 12(1):1-222. PMID: 26799652; PMCID: PMC4835977.
    Citations: 2567     Fields:    Translation:HumansAnimals
  51. Truong-Bolduc QC, Bolduc GR, Medeiros H, Vyas JM, Wang Y, Hooper DC. Role of the Tet38 Efflux Pump in Staphylococcus aureus Internalization and Survival in Epithelial Cells. Infect Immun. 2015 Nov; 83(11):4362-72. PMID: 26324534; PMCID: PMC4598397.
    Citations: 25     Fields:    Translation:HumansAnimalsCells
  52. Jones CN, Dimisko L, Forrest K, Judice K, Poznansky MC, Markmann JF, Vyas JM, Irimia D. Human Neutrophils Are Primed by Chemoattractant Gradients for Blocking the Growth of Aspergillus fumigatus. J Infect Dis. 2016 Feb 01; 213(3):465-75. PMID: 26272935; PMCID: PMC4704668.
    Citations: 21     Fields:    Translation:HumansAnimalsCells
  53. Begun J, Lassen KG, Jijon HB, Baxt LA, Goel G, Heath RJ, Ng A, Tam JM, Kuo SY, Villablanca EJ, Fagbami L, Oosting M, Kumar V, Schenone M, Carr SA, Joosten LA, Vyas JM, Daly MJ, Netea MG, Brown GD, Wijmenga C, Xavier RJ. Integrated Genomics of Crohn's Disease Risk Variant Identifies a Role for CLEC12A in Antibacterial Autophagy. Cell Rep. 2015 Jun 30; 11(12):1905-18. PMID: 26095365; PMCID: PMC4507440.
    Citations: 16     Fields:    Translation:HumansAnimalsCells
  54. Klassert TE, Hanisch A, Bräuer J, Klaile E, Heyl KA, Mansour MK, Tam JM, Vyas JM, Slevogt H. Erratum to: Modulatory role of vitamin A on the Candida albicans-induced immune response in human monocytes. Med Microbiol Immunol. 2014 Dec; 203(6):425. PMID: 25298302.
  55. Klassert TE, Hanisch A, Bräuer J, Klaile E, Heyl KA, Mansour MK, Mansour MM, Tam JM, Vyas JM, Slevogt H. Modulatory role of vitamin A on the Candida albicans-induced immune response in human monocytes. Med Microbiol Immunol. 2014 Dec; 203(6):415-24. PMID: 25129478.
    Citations: 11     Fields:    Translation:HumansAnimalsCells
  56. Tam JM, Mansour MK, Khan NS, Seward M, Puranam S, Tanne A, Sokolovska A, Becker CE, Acharya M, Baird MA, Choi AM, Davidson MW, Segal BH, Lacy-Hulbert A, Stuart LM, Xavier RJ, Vyas JM. Dectin-1-dependent LC3 recruitment to phagosomes enhances fungicidal activity in macrophages. J Infect Dis. 2014 Dec 01; 210(11):1844-54. PMID: 24842831; PMCID: PMC4271056.
    Citations: 53     Fields:    Translation:AnimalsCells
  57. Kasper L, Seider K, Gerwien F, Allert S, Brunke S, Schwarzmüller T, Ames L, Zubiria-Barrera C, Mansour MK, Becken U, Barz D, Vyas JM, Reiling N, Haas A, Haynes K, Kuchler K, Hube B. Identification of Candida glabrata genes involved in pH modulation and modification of the phagosomal environment in macrophages. PLoS One. 2014; 9(5):e96015. PMID: 24789333; PMCID: PMC4006850.
    Citations: 26     Fields:    Translation:HumansAnimalsCells
  58. Mansour MK, Reedy JL, Tam JM, Vyas JM. Macrophage Cryptococcus interactions: an update. Curr Fungal Infect Rep. 2014 Mar 01; 8(1):109-115. PMID: 24660045.
    Citations: 10     
  59. Vyas JM, González RG, Pierce VM. Case records of the Massachusetts General Hospital. Case 15-2013. A 76-year-old man with fever, worsening renal function, and altered mental status. N Engl J Med. 2013 May 16; 368(20):1919-27. PMID: 23675661.
    Citations: 1     Fields:    Translation:HumansCells
  60. Mansour MK, Tam JM, Khan NS, Seward M, Davids PJ, Puranam S, Sokolovska A, Sykes DB, Dagher Z, Becker C, Tanne A, Reedy JL, Stuart LM, Vyas JM. Dectin-1 activation controls maturation of ß-1,3-glucan-containing phagosomes. J Biol Chem. 2013 May 31; 288(22):16043-54. PMID: 23609446.
    Citations: 37     Fields:    Translation:AnimalsCells
  61. Grimm MJ, Vethanayagam RR, Almyroudis NG, Dennis CG, Khan AN, D'Auria AC, Singel KL, Davidson BA, Knight PR, Blackwell TS, Hohl TM, Mansour MK, Vyas JM, Röhm M, Urban CF, Kelkka T, Holmdahl R, Segal BH. Monocyte- and macrophage-targeted NADPH oxidase mediates antifungal host defense and regulation of acute inflammation in mice. J Immunol. 2013 Apr 15; 190(8):4175-84. PMID: 23509361; PMCID: PMC3622122.
    Citations: 38     Fields:    Translation:AnimalsCells
  62. Huett A, Heath RJ, Begun J, Sassi SO, Baxt LA, Vyas JM, Goldberg MB, Xavier RJ. The LRR and RING domain protein LRSAM1 is an E3 ligase crucial for ubiquitin-dependent autophagy of intracellular Salmonella Typhimurium. Cell Host Microbe. 2012 Dec 13; 12(6):778-90. PMID: 23245322.
    Citations: 121     Fields:    Translation:HumansCells
  63. Mansour MK, Tam JM, Vyas JM. The cell biology of the innate immune response to Aspergillus fumigatus. Ann N Y Acad Sci. 2012 Dec; 1273:78-84. PMID: 23230841.
    Citations: 10     Fields:    Translation:HumansAnimalsCells
  64. Vyas JM. The dendritic cell: the general of the army. Virulence. 2012 Nov 15; 3(7):601-2. PMID: 23221475.
    Citations: 3     Fields:    Translation:HumansAnimalsCells
  65. Vyas JM. Insights into dendritic cell function using advanced imaging modalities. Virulence. 2012 Nov 15; 3(7):690-4. PMID: 23221474.
    Citations: 1     Fields:    Translation:HumansAnimalsCells
  66. Vyas JM, Marasco WA. Fatal fulminant hepatic failure from adenovirus in allogeneic bone marrow transplant patients. Case Rep Infect Dis. 2012; 2012:463569. PMID: 22928129.
    Citations: 6     
  67. Tam JM, Mansour MK, Khan NS, Yoder NC, Vyas JM. Use of fungal derived polysaccharide-conjugated particles to probe Dectin-1 responses in innate immunity. Integr Biol (Camb). 2012 Feb; 4(2):220-7. PMID: 22200052.
    Citations: 17     Fields:    Translation:HumansAnimalsCells
  68. Coleman JJ, Muhammed M, Kasperkovitz PV, Vyas JM, Mylonakis E. Fusarium pathogenesis investigated using Galleria mellonella as a heterologous host. Fungal Biol. 2011 Dec; 115(12):1279-89. PMID: 22115447.
    Citations: 24     Fields:    Translation:HumansAnimals
  69. Mansour MK, Vyas JM, Levitz SM. Dynamic virulence: real-time assessment of intracellular pathogenesis links Cryptococcus neoformans phenotype with clinical outcome. mBio. 2011; 2(5). PMID: 21954307.
    Citations: 12     Fields:    Translation:HumansAnimalsCells
  70. Kasperkovitz PV, Khan NS, Tam JM, Mansour MK, Davids PJ, Vyas JM. Toll-like receptor 9 modulates macrophage antifungal effector function during innate recognition of Candida albicans and Saccharomyces cerevisiae. Infect Immun. 2011 Dec; 79(12):4858-67. PMID: 21947771.
    Citations: 27     Fields:    Translation:HumansAnimalsCells
  71. Tam JM, Castro CE, Heath RJ, Mansour MK, Cardenas ML, Xavier RJ, Lang MJ, Vyas JM. Use of an optical trap for study of host-pathogen interactions for dynamic live cell imaging. J Vis Exp. 2011 Jul 28; (53). PMID: 21841755.
    Citations: 4     Fields:    Translation:HumansAnimalsCells
  72. Vyas JM. The duality of Aspergillus terreus: Differential immune responses to distinct conidia. Virulence. 2011 May-Jun; 2(3):181-4. PMID: 21636969.
    Citations: 4     Fields:    Translation:HumansAnimalsCells
  73. Modi P, Rizvi J, Pal B, Bharadwaj R, Trivedi P, Trivedi A, Patel K, Shah K, Vyas J, Sharma S, Shah K, Chauhan R, Trivedi H. Laparoscopic kidney transplantation: an initial experience. Am J Transplant. 2011 Jun; 11(6):1320-4. PMID: 21486384.
    Citations: 12     Fields:    Translation:Humans
  74. Tam JM, Castro CE, Heath RJ, Cardenas ML, Xavier RJ, Lang MJ, Vyas JM. Control and manipulation of pathogens with an optical trap for live cell imaging of intercellular interactions. PLoS One. 2010 Dec 31; 5(12):e15215. PMID: 21217821.
    Citations: 13     Fields:    Translation:HumansAnimalsCells
  75. Xia Y, Cortez-Retamozo V, Niederkofler V, Salie R, Chen S, Samad TA, Hong CC, Arber S, Vyas JM, Weissleder R, Pittet MJ, Lin HY. Dragon (repulsive guidance molecule b) inhibits IL-6 expression in macrophages. J Immunol. 2011 Feb 01; 186(3):1369-76. PMID: 21187450; PMCID: PMC3670585.
    Citations: 28     Fields:    Translation:AnimalsCells
  76. Artavanis-Tsakonas K, Kasperkovitz PV, Papa E, Cardenas ML, Khan NS, Van der Veen AG, Ploegh HL, Vyas JM. The tetraspanin CD82 is specifically recruited to fungal and bacterial phagosomes prior to acidification. Infect Immun. 2011 Mar; 79(3):1098-106. PMID: 21149584.
    Citations: 15     Fields:    Translation:HumansAnimalsCells
  77. Kasperkovitz PV, Cardenas ML, Vyas JM. TLR9 is actively recruited to Aspergillus fumigatus phagosomes and requires the N-terminal proteolytic cleavage domain for proper intracellular trafficking. J Immunol. 2010 Dec 15; 185(12):7614-22. PMID: 21059889; PMCID: PMC3600358.
    Citations: 38     Fields:    Translation:HumansAnimalsCells
  78. Bender Ignacio RA, Liu AY, Sohani AR, Vyas JM. Hodgkin's lymphoma masquerading as vertebral osteomyelitis in a man with diabetes: a case report. J Med Case Rep. 2010 Apr 06; 4:102. PMID: 20370895.
    Citations: 3     Fields:    
  79. Vyas JM, Van der Veen AG, Ploegh HL. The known unknowns of antigen processing and presentation. Nat Rev Immunol. 2008 Aug; 8(8):607-18. PMID: 18641646.
    Citations: 226     Fields:    Translation:HumansAnimalsCells
  80. Vyas JM, Telford SR, Robbins GK. Treatment of refractory Babesia microti infection with atovaquone-proguanil in an HIV-infected patient: case report. Clin Infect Dis. 2007 Dec 15; 45(12):1588-90. PMID: 18190320.
    Citations: 16     Fields:    Translation:HumansAnimals
  81. Vyas JM, Kim YM, Artavanis-Tsakonas K, Love JC, Van der Veen AG, Ploegh HL. Tubulation of class II MHC compartments is microtubule dependent and involves multiple endolysosomal membrane proteins in primary dendritic cells. J Immunol. 2007 Jun 01; 178(11):7199-210. PMID: 17513769; PMCID: PMC2806821.
    Citations: 54     Fields:    Translation:HumansAnimalsCells
  82. Cernichiari E, Myers GJ, Ballatori N, Zareba G, Vyas J, Clarkson T. The biological monitoring of prenatal exposure to methylmercury. Neurotoxicology. 2007 Sep; 28(5):1015-22. PMID: 17382399.
    Citations: 22     Fields:    Translation:HumansPHPublic Health
  83. Vyas JM, Kasmar A, Chang HR, Holden J, Hohmann E. Abdominal abscesses due to actinomycosis after laparoscopic cholecystectomy: case reports and review. Clin Infect Dis. 2007 Jan 15; 44(2):e1-4. PMID: 17173208.
    Citations: 5     Fields:    Translation:HumansCells
  84. Trivedi V, Zhang SC, Castoreno AB, Stockinger W, Shieh EC, Vyas JM, Frickel EM, Nohturfft A. Immunoglobulin G signaling activates lysosome/phagosome docking. Proc Natl Acad Sci U S A. 2006 Nov 28; 103(48):18226-31. PMID: 17110435; PMCID: PMC1838734.
    Citations: 10     Fields:    Translation:HumansAnimalsCells
  85. Artavanis-Tsakonas K, Love JC, Ploegh HL, Vyas JM. Recruitment of CD63 to Cryptococcus neoformans phagosomes requires acidification. Proc Natl Acad Sci U S A. 2006 Oct 24; 103(43):15945-50. PMID: 17043215; PMCID: PMC1635107.
    Citations: 35     Fields:    Translation:HumansAnimalsCells
  86. Wozniak KL, Vyas JM, Levitz SM. In vivo role of dendritic cells in a murine model of pulmonary cryptococcosis. Infect Immun. 2006 Jul; 74(7):3817-24. PMID: 16790753; PMCID: PMC1489690.
    Citations: 49     Fields:    Translation:AnimalsCells
  87. Gewurz B, Vyas JM, and Ploegh H.L. Subversion of adaptive immunity: immune evasion of T cells. Human Herpesviruses: Biology, Therapy and Immunoprophylaxis. Editor: Ann M. Arvin, MD. 2006.
  88. Niess JH, Brand S, Gu X, Landsman L, Jung S, McCormick BA, Vyas JM, Boes M, Ploegh HL, Fox JG, Littman DR, Reinecker HC. CX3CR1-mediated dendritic cell access to the intestinal lumen and bacterial clearance. Science. 2005 Jan 14; 307(5707):254-8. PMID: 15653504.
    Citations: 590     Fields:    Translation:AnimalsCells
  89. Fiebiger E, Hirsch C, Vyas JM, Gordon E, Ploegh HL, Tortorella D. Dissection of the dislocation pathway for type I membrane proteins with a new small molecule inhibitor, eeyarestatin. Mol Biol Cell. 2004 Apr; 15(4):1635-46. PMID: 14767067; PMCID: PMC379262.
    Citations: 61     Fields:    Translation:HumansCells
  90. Jatin M Vyas, MD, PhD Mary Jane Ferraro, PhD, MPH. Overview of antibacterial susceptibility testing. 2003.
  91. Jatin M Vyas, MD, PhD Mary Jane Ferraro, PhD, MPH. Antibiotic susceptibility testing in specific clinical situations. 2003.
  92. Dow SW, Roberts A, Vyas J, Rodgers J, Rich RR, Orme I, Potter TA. Immunization with f-Met peptides induces immune reactivity against Mycobacterium tuberculosis. Tuber Lung Dis. 2000; 80(1):5-13. PMID: 10897379.
    Citations: 1     Fields:    Translation:AnimalsCellsPHPublic Health
  93. Vyas JM, Rodgers JR, Rich RR. H-2M3a violates the paradigm for major histocompatibility complex class I peptide binding. J Exp Med. 1995 May 01; 181(5):1817-25. PMID: 7722457; PMCID: PMC2191989.
    Citations: 5     Fields:    Translation:HumansAnimalsCells
  94. Vyas JM, Lamphear JL and Rich RR. The language of immunology. Clinical Immunology: Principles and Practice. Editor: Robert R. Rich. 1995; G1-8.
  95. Vyas JM. The peptide binding specificity of the MHC class I-b molecule, H-2M3a. 1994.
  96. Shawar SM, Vyas JM, Rodgers JR, Rich RR. Antigen presentation by major histocompatibility complex class I-B molecules. Annu Rev Immunol. 1994; 12:839-80. PMID: 8011299.
    Citations: 63     Fields:    Translation:HumansAnimalsCells
  97. Vyas JM, Rich RR, Howell DD, Shawar SM, Rodgers JR. Availability of endogenous peptides limits expression of an M3a-Ld major histocompatibility complex class I chimera. J Exp Med. 1994 Jan 01; 179(1):155-65. PMID: 8270862; PMCID: PMC2191314.
    Citations: 7     Fields:    Translation:AnimalsCells
  98. Shawar SM, Vyas JM, Shen E, Rodgers JR, Rich RR. Differential amino-terminal anchors for peptide binding to H-2M3a or H-2Kb and H-2Db. J Immunol. 1993 Jul 01; 151(1):201-10. PMID: 7686932.
    Citations: 8     Fields:    Translation:AnimalsCells
  99. Vyas JM, Shawar SM, Rodgers JR, Cook RG, Rich RR. Biochemical specificity of H-2M3a. Stereospecificity and space-filling requirements at position 1 maintain N-formyl peptide binding. J Immunol. 1992 Dec 01; 149(11):3605-11. PMID: 1431130.
    Citations: 10     Fields:    Translation:AnimalsCells
  100. Shawar SM, Vyas JM, Rodgers JR, Cook RG, Rich RR. Specialized functions of major histocompatibility complex class I molecules. II. Hmt binds N-formylated peptides of mitochondrial and prokaryotic origin. J Exp Med. 1991 Oct 01; 174(4):941-4. PMID: 1919442; PMCID: PMC2118972.
    Citations: 22     Fields:    Translation:AnimalsCells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.