Harvard Catalyst Profiles

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Michael L. Fitzgerald, Ph.D.


The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. R01HL140977 (BUKRINSKY, MICHAEL ILYA) Aug 15, 2018 - May 31, 2022
    Epigenetic Reprogramming in HIV-Associated Cardio-Vascular Disease
    Role: Co-Principal Investigator
  2. R01HL131624 (LATZ, EICKE) Jul 1, 2017 - Apr 30, 2021
    Epigenetic Reprogramming in Atherosclerosis
    Role: Co-Principal Investigator
  3. R01HL112661 (FITZGERALD, MICHAEL LEO) Sep 27, 2012 - Dec 31, 2018
    HDL prevention of cholesterol crystal inflammation in HIV disease
    Role: Principal Investigator
  4. R01HL101274 (BUKRINSKY, MICHAEL ILYA) Aug 15, 2010 - Dec 31, 2016
    HIV Disease and Impairement of High Density Lipoprotein Metabolism
    Role: Co-Principal Investigator
  5. R01HL074136 (FITZGERALD, MICHAEL LEO) Aug 1, 2005 - Apr 30, 2010
    ABCA1 cholesterol efflux &protein-protein interactions
    Role: Principal Investigator

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Noh HJ, Turner-Maier J, Schulberg SA, Fitzgerald ML, Johnson J, Allen KN, Hückstädt LA, Batten AJ, Alfoldi J, Costa DP, Karlsson EK, Zapol WM, Buys ES, Lindblad-Toh K, Hindle AG. The Antarctic Weddell seal genome reveals evidence of selection on cardiovascular phenotype and lipid handling. Commun Biol. 2022 02 17; 5(1):140. PMID: 35177770; PMCID: PMC8854659.
    Citations: 3     Translation:Animals
  2. Park MH, Suhalim JL, Elmastour F, Singha SK, Imafuku T, Venkatnarayan R, Christ A, Grebe A, Oppelt SA, Sviridov D, Bukrinsky M, Latz E, Potma EO, Fitzgerald ML. Non-linear optical imaging of atherosclerotic plaques in the context of SIV and HIV infection prominently detects crystalline cholesterol esters. PLoS One. 2021; 16(5):e0251599. PMID: 33984028.
    Citations:    Fields:    Translation:AnimalsCells
  3. Imafuku T, Watanabe H, Oniki K, Yoshida A, Kato H, Nakano T, Tokumaru K, Fujita I, Arimura N, Maeda H, Sakamoto Y, Kondo N, Morita A, Saruwatari J, Tanaka M, Matsushita K, Wada T, Fukagawa M, Otagiri M, Fitzgerald ML, Jinnouchi H, Maruyama T. Cysteinylated Albumin as a Potential Biomarker for the Progression of Kidney Disease in Patients With Type 2 Diabetes. Diabetes Care. 2021 06; 44(6):e115-e117. PMID: 33905348; PMCID: PMC8247487.
    Citations: 5     Fields:    Translation:Humans
  4. Aikawa T, Ren Y, Holm ML, Asmann YW, Alam A, Fitzgerald ML, Bu G, Kanekiyo T. ABCA7 Regulates Brain Fatty Acid Metabolism During LPS-Induced Acute Inflammation. Front Neurosci. 2021; 15:647974. PMID: 33897360.
    Citations: 4     
  5. Murray Stewart T, Desai AA, Fitzgerald ML, Marton LJ, Casero RA. A phase I dose-escalation study of the polyamine analog PG-11047 in patients with advanced solid tumors. Cancer Chemother Pharmacol. 2020 06; 85(6):1089-1096. PMID: 32447421.
    Citations: 5     Fields:    Translation:HumansCTClinical Trials
  6. Aikawa T, Ren Y, Yamazaki Y, Tachibana M, Johnson MR, Anderson CT, Martens YA, Holm ML, Asmann YW, Saito T, Saido TC, Fitzgerald ML, Bu G, Kanekiyo T. ABCA7 haplodeficiency disturbs microglial immune responses in the mouse brain. Proc Natl Acad Sci U S A. 2019 11 19; 116(47):23790-23796. PMID: 31690660; PMCID: PMC6876254.
    Citations: 18     Fields:    Translation:AnimalsCells
  7. Low H, Hoang A, Pushkarsky T, Dubrovsky L, Dewar E, Di Yacovo MS, Mukhamedova N, Cheng L, Downs C, Simon G, Saumoy M, Hill AF, Fitzgerald ML, Nestel P, Dart A, Hoy J, Bukrinsky M, Sviridov D. HIV disease, metabolic dysfunction and atherosclerosis: A three year prospective study. PLoS One. 2019; 14(4):e0215620. PMID: 30998801.
    Citations: 10     Fields:    Translation:HumansCellsCTClinical Trials
  8. Boucher LM, O'Brien KK, Baxter LN, Fitzgerald ML, Liddy CE, Kendall CE. Healthy aging with HIV: The role of self-management support. Patient Educ Couns. 2019 08; 102(8):1565-1569. PMID: 30827568.
    Citations: 7     Fields:    Translation:Humans
  9. Bagchi A, Batten AJ, Levin M, Allen KN, Fitzgerald ML, Hückstädt LA, Costa DP, Buys ES, Hindle AG. Intrinsic anti-inflammatory properties in the serum of two species of deep-diving seal. J Exp Biol. 2018 07 09; 221(Pt 13). PMID: 29748216.
    Citations: 8     Fields:    Translation:AnimalsCells
  10. Christ A, Günther P, Lauterbach MAR, Duewell P, Biswas D, Pelka K, Scholz CJ, Oosting M, Haendler K, Baßler K, Klee K, Schulte-Schrepping J, Ulas T, Moorlag SJCFM, Kumar V, Park MH, Joosten LAB, Groh LA, Riksen NP, Espevik T, Schlitzer A, Li Y, Fitzgerald ML, Netea MG, Schultze JL, Latz E. Western Diet Triggers NLRP3-Dependent Innate Immune Reprogramming. Cell. 2018 01 11; 172(1-2):162-175.e14. PMID: 29328911; PMCID: PMC6324559.
    Citations: 352     Fields:    Translation:HumansAnimalsCells
  11. Toribio M, Park MH, Zanni MV, Robbins GK, Burdo TH, Williams KC, Feldpausch MN, Stone L, Melbourne K, Grinspoon SK, Fitzgerald ML. HDL Cholesterol Efflux Capacity in Newly Diagnosed HIV and Effects of Antiretroviral Therapy. J Clin Endocrinol Metab. 2017 11 01; 102(11):4250-4259. PMID: 28945911; PMCID: PMC5673269.
    Citations: 2     Fields:    Translation:HumansAnimalsCellsCTClinical Trials
  12. Nowyhed HN, Chandra S, Kiosses W, Marcovecchio P, Andary F, Zhao M, Fitzgerald ML, Kronenberg M, Hedrick CC. ATP Binding Cassette Transporter ABCA7 Regulates NKT Cell Development and Function by Controlling CD1d Expression and Lipid Raft Content. Sci Rep. 2017 01 16; 7:40273. PMID: 28091533.
    Citations: 13     Fields:    Translation:AnimalsCells
  13. Zimmer S, Grebe A, Bakke SS, Bode N, Halvorsen B, Ulas T, Skjelland M, De Nardo D, Labzin LI, Kerksiek A, Hempel C, Heneka MT, Hawxhurst V, Fitzgerald ML, Trebicka J, Björkhem I, Gustafsson JÅ, Westerterp M, Tall AR, Wright SD, Espevik T, Schultze JL, Nickenig G, Lütjohann D, Latz E. Cyclodextrin promotes atherosclerosis regression via macrophage reprogramming. Sci Transl Med. 2016 Apr 06; 8(333):333ra50. PMID: 27053774.
    Citations: 98     Fields:    Translation:HumansAnimalsCells
  14. Sakae N, Liu CC, Shinohara M, Frisch-Daiello J, Ma L, Yamazaki Y, Tachibana M, Younkin L, Kurti A, Carrasquillo MM, Zou F, Sevlever D, Bisceglio G, Gan M, Fol R, Knight P, Wang M, Han X, Fryer JD, Fitzgerald ML, Ohyagi Y, Younkin SG, Bu G, Kanekiyo T. ABCA7 Deficiency Accelerates Amyloid-ß Generation and Alzheimer's Neuronal Pathology. J Neurosci. 2016 Mar 30; 36(13):3848-59. PMID: 27030769; PMCID: PMC4812140.
    Citations: 58     Fields:    Translation:HumansAnimalsCells
  15. Tamehiro N, Park MH, Hawxhurst V, Nagpal K, Adams ME, Zannis VI, Golenbock DT, Fitzgerald ML. LXR Agonism Upregulates the Macrophage ABCA1/Syntrophin Protein Complex That Can Bind ApoA-I and Stabilized ABCA1 Protein, but Complex Loss Does Not Inhibit Lipid Efflux. Biochemistry. 2015 Nov 24; 54(46):6931-41. PMID: 26506427; PMCID: PMC4874254.
    Citations: 6     Fields:    Translation:AnimalsCells
  16. Siegel MO, Borkowska AG, Dubrovsky L, Roth M, Welti R, Roberts AD, Parenti DM, Simon GL, Sviridov D, Simmens S, Bukrinsky M, Fitzgerald ML. HIV infection induces structural and functional changes in high density lipoproteins. Atherosclerosis. 2015 Nov; 243(1):19-29. PMID: 26343868.
    Citations: 15     Fields:    Translation:HumansCells
  17. Ramezani A, Dubrovsky L, Pushkarsky T, Sviridov D, Karandish S, Raj DS, Fitzgerald ML, Bukrinsky M. Stimulation of Liver X Receptor Has Potent Anti-HIV Effects in a Humanized Mouse Model of HIV Infection. J Pharmacol Exp Ther. 2015 Sep; 354(3):376-83. PMID: 26126533; PMCID: PMC4538872.
    Citations: 12     Fields:    Translation:HumansAnimalsCells
  18. Midtbø LK, Borkowska AG, Bernhard A, Rønnevik AK, Lock EJ, Fitzgerald ML, Torstensen BE, Liaset B, Brattelid T, Pedersen TL, Newman JW, Kristiansen K, Madsen L. Intake of farmed Atlantic salmon fed soybean oil increases hepatic levels of arachidonic acid-derived oxylipins and ceramides in mice. J Nutr Biochem. 2015 Jun; 26(6):585-95. PMID: 25776459.
    Citations: 13     Fields:    Translation:Animals
  19. Lo J, Rosenberg ES, Fitzgerald ML, Bazner SB, Ihenachor EJ, Hawxhurst V, Borkowska AH, Wei J, Zimmerman CO, Burdo TH, Williams KC, Freeman MW, Grinspoon SK. High-density lipoprotein-mediated cholesterol efflux capacity is improved by treatment with antiretroviral therapy in acute human immunodeficiency virus infection. Open Forum Infect Dis. 2014 Dec; 1(3):ofu108. PMID: 25734176; PMCID: PMC4324225.
    Citations: 15     
  20. Jennelle L, Hunegnaw R, Dubrovsky L, Pushkarsky T, Fitzgerald ML, Sviridov D, Popratiloff A, Brichacek B, Bukrinsky M. HIV-1 protein Nef inhibits activity of ATP-binding cassette transporter A1 by targeting endoplasmic reticulum chaperone calnexin. J Biol Chem. 2014 Oct 17; 289(42):28870-84. PMID: 25170080; PMCID: PMC4200247.
    Citations: 23     Fields:    Translation:HumansCells
  21. Zanni MV, Kelesidis T, Fitzgerald ML, Lo J, Abbara S, Wai B, Marmarelis E, Hernandez NJ, Yang OO, Currier JS, Grinspoon SK. HDL redox activity is increased in HIV-infected men in association with macrophage activation and non-calcified coronary atherosclerotic plaque. Antivir Ther. 2014; 19(8):805-811. PMID: 24535655; PMCID: PMC4423391.
    Citations: 13     Fields:    Translation:HumansCells
  22. De Nardo D, Labzin LI, Kono H, Seki R, Schmidt SV, Beyer M, Xu D, Zimmer S, Lahrmann C, Schildberg FA, Vogelhuber J, Kraut M, Ulas T, Kerksiek A, Krebs W, Bode N, Grebe A, Fitzgerald ML, Hernandez NJ, Williams BR, Knolle P, Kneilling M, Röcken M, Lütjohann D, Wright SD, Schultze JL, Latz E. High-density lipoprotein mediates anti-inflammatory reprogramming of macrophages via the transcriptional regulator ATF3. Nat Immunol. 2014 Feb; 15(2):152-60. PMID: 24317040.
    Citations: 162     Fields:    Translation:HumansAnimalsCells
  23. Haller JF, Cavallaro P, Hernandez NJ, Dolat L, Soscia SJ, Welti R, Grabowski GA, Fitzgerald ML, Freeman MW. Endogenous ß-glucocerebrosidase activity in Abca12?/?epidermis elevates ceramide levels after topical lipid application but does not restore barrier function. J Lipid Res. 2014 Mar; 55(3):493-503. PMID: 24293640.
    Citations: 3     Fields:    Translation:HumansAnimalsCells
  24. Cui HL, Grant A, Mukhamedova N, Pushkarsky T, Jennelle L, Dubrovsky L, Gaus K, Fitzgerald ML, Sviridov D, Bukrinsky M. HIV-1 Nef mobilizes lipid rafts in macrophages through a pathway that competes with ABCA1-dependent cholesterol efflux. J Lipid Res. 2012 Apr; 53(4):696-708. PMID: 22262807; PMCID: PMC3307646.
    Citations: 46     Fields:    Translation:HumansAnimalsCells
  25. Tanaka N, Abe-Dohmae S, Iwamoto N, Fitzgerald ML, Yokoyama S. HMG-CoA reductase inhibitors enhance phagocytosis by upregulating ATP-binding cassette transporter A7. Atherosclerosis. 2011 Aug; 217(2):407-14. PMID: 21762915.
    Citations: 20     Fields:    Translation:HumansAnimalsCells
  26. Kim WS, Hill AF, Fitzgerald ML, Freeman MW, Evin G, Garner B. Wild type and Tangier disease ABCA1 mutants modulate cellular amyloid-ß production independent of cholesterol efflux activity. J Alzheimers Dis. 2011; 27(2):441-52. PMID: 21860089.
    Citations: 6     Fields:    Translation:HumansAnimalsCells
  27. Mujawar Z, Tamehiro N, Grant A, Sviridov D, Bukrinsky M, Fitzgerald ML. Mutation of the ATP cassette binding transporter A1 (ABCA1) C-terminus disrupts HIV-1 Nef binding but does not block the Nef enhancement of ABCA1 protein degradation. Biochemistry. 2010 Sep 28; 49(38):8338-49. PMID: 20731376.
    Citations: 22     Fields:    Translation:AnimalsCells
  28. Asztalos BF, Mujawar Z, Morrow MP, Grant A, Pushkarsky T, Wanke C, Shannon R, Geyer M, Kirchhoff F, Sviridov D, Fitzgerald ML, Bukrinsky M, Mansfield KG. Circulating Nef induces dyslipidemia in simian immunodeficiency virus-infected macaques by suppressing cholesterol efflux. J Infect Dis. 2010 Aug 15; 202(4):614-23. PMID: 20617930; PMCID: PMC2932757.
    Citations: 37     Fields:    Translation:AnimalsCells
  29. Tanaka N, Abe-Dohmae S, Iwamoto N, Fitzgerald ML, Yokoyama S. Helical apolipoproteins of high-density lipoprotein enhance phagocytosis by stabilizing ATP-binding cassette transporter A7. J Lipid Res. 2010 Sep; 51(9):2591-9. PMID: 20495215.
    Citations: 30     Fields:    Translation:HumansAnimalsCells
  30. Rayner KJ, Suárez Y, Dávalos A, Parathath S, Fitzgerald ML, Tamehiro N, Fisher EA, Moore KJ, Fernández-Hernando C. MiR-33 contributes to the regulation of cholesterol homeostasis. Science. 2010 Jun 18; 328(5985):1570-3. PMID: 20466885; PMCID: PMC3114628.
    Citations: 569     Fields:    Translation:HumansAnimalsCells
  31. Okuhira K, Fitzgerald ML, Tamehiro N, Ohoka N, Suzuki K, Sawada J, Naito M, Nishimaki-Mogami T. Binding of PDZ-RhoGEF to ATP-binding cassette transporter A1 (ABCA1) induces cholesterol efflux through RhoA activation and prevention of transporter degradation. J Biol Chem. 2010 May 21; 285(21):16369-77. PMID: 20348106.
    Citations: 17     Fields:    Translation:HumansCells
  32. Fitzgerald ML, Mujawar Z, Tamehiro N. ABC transporters, atherosclerosis and inflammation. Atherosclerosis. 2010 Aug; 211(2):361-70. PMID: 20138281.
    Citations: 69     Fields:    Translation:HumansAnimalsCells
  33. Tamehiro N, Mujawar Z, Zhou S, Zhuang DZ, Hornemann T, von Eckardstein A, Fitzgerald ML. Cell polarity factor Par3 binds SPTLC1 and modulates monocyte serine palmitoyltransferase activity and chemotaxis. J Biol Chem. 2009 Sep 11; 284(37):24881-90. PMID: 19592499.
    Citations: 11     Fields:    Translation:HumansCells
  34. Zuo Y, Zhuang DZ, Han R, Isaac G, Tobin JJ, McKee M, Welti R, Brissette JL, Fitzgerald ML, Freeman MW. ABCA12 maintains the epidermal lipid permeability barrier by facilitating formation of ceramide linoleic esters. J Biol Chem. 2008 Dec 26; 283(52):36624-35. PMID: 18957418.
    Citations: 41     Fields:    Translation:Animals
  35. Tamehiro N, Zhou S, Okuhira K, Benita Y, Brown CE, Zhuang DZ, Latz E, Hornemann T, von Eckardstein A, Xavier RJ, Freeman MW, Fitzgerald ML. SPTLC1 binds ABCA1 to negatively regulate trafficking and cholesterol efflux activity of the transporter. Biochemistry. 2008 Jun 10; 47(23):6138-47. PMID: 18484747.
    Citations: 20     Fields:    Translation:HumansAnimalsCells
  36. Fitzgerald ML, Xavier R, Haley KJ, Welti R, Goss JL, Brown CE, Zhuang DZ, Bell SA, Lu N, McKee M, Seed B, Freeman MW. ABCA3 inactivation in mice causes respiratory failure, loss of pulmonary surfactant, and depletion of lung phosphatidylglycerol. J Lipid Res. 2007 Mar; 48(3):621-32. PMID: 17142808.
    Citations: 70     Fields:    Translation:Animals
  37. Huang ZH, Fitzgerald ML, Mazzone T. Distinct cellular loci for the ABCA1-dependent and ABCA1-independent lipid efflux mediated by endogenous apolipoprotein E expression. Arterioscler Thromb Vasc Biol. 2006 Jan; 26(1):157-62. PMID: 16254198.
    Citations: 21     Fields:    Translation:AnimalsCells
  38. Okuhira K, Fitzgerald ML, Sarracino DA, Manning JJ, Bell SA, Goss JL, Freeman MW. Purification of ATP-binding cassette transporter A1 and associated binding proteins reveals the importance of beta1-syntrophin in cholesterol efflux. J Biol Chem. 2005 Nov 25; 280(47):39653-64. PMID: 16192269.
    Citations: 22     Fields:    Translation:HumansAnimalsCells
  39. Kim WS, Fitzgerald ML, Kang K, Okuhira K, Bell SA, Manning JJ, Koehn SL, Lu N, Moore KJ, Freeman MW. Abca7 null mice retain normal macrophage phosphatidylcholine and cholesterol efflux activity despite alterations in adipose mass and serum cholesterol levels. J Biol Chem. 2005 Feb 04; 280(5):3989-95. PMID: 15550377.
    Citations: 60     Fields:    Translation:AnimalsCells
  40. Fukuchi J, Hiipakka RA, Kokontis JM, Hsu S, Ko AL, Fitzgerald ML, Liao S. Androgenic suppression of ATP-binding cassette transporter A1 expression in LNCaP human prostate cancer cells. Cancer Res. 2004 Nov 01; 64(21):7682-5. PMID: 15520169.
    Citations: 33     Fields:    Translation:HumansCells
  41. Fitzgerald ML, Okuhira K, Short GF, Manning JJ, Bell SA, Freeman MW. ATP-binding cassette transporter A1 contains a novel C-terminal VFVNFA motif that is required for its cholesterol efflux and ApoA-I binding activities. J Biol Chem. 2004 Nov 12; 279(46):48477-85. PMID: 15347662.
    Citations: 26     Fields:    Translation:HumansAnimalsCells
  42. Nieland TJ, Chroni A, Fitzgerald ML, Maliga Z, Zannis VI, Kirchhausen T, Krieger M. Cross-inhibition of SR-BI- and ABCA1-mediated cholesterol transport by the small molecules BLT-4 and glyburide. J Lipid Res. 2004 Jul; 45(7):1256-65. PMID: 15102890.
    Citations: 41     Fields:    Translation:HumansCells
  43. Chroni A, Liu T, Fitzgerald ML, Freeman MW, Zannis VI. Cross-linking and lipid efflux properties of apoA-I mutants suggest direct association between apoA-I helices and ABCA1. Biochemistry. 2004 Feb 24; 43(7):2126-39. PMID: 14967052.
    Citations: 33     Fields:    Translation:HumansAnimalsCells
  44. Fitzgerald ML, Morris AL, Chroni A, Mendez AJ, Zannis VI, Freeman MW. ABCA1 and amphipathic apolipoproteins form high-affinity molecular complexes required for cholesterol efflux. J Lipid Res. 2004 Feb; 45(2):287-94. PMID: 14617740.
    Citations: 42     Fields:    Translation:HumansCells
  45. Fukumoto H, Deng A, Irizarry MC, Fitzgerald ML, Rebeck GW. Induction of the cholesterol transporter ABCA1 in central nervous system cells by liver X receptor agonists increases secreted Abeta levels. J Biol Chem. 2002 Dec 13; 277(50):48508-13. PMID: 12384498.
    Citations: 46     Fields:    Translation:AnimalsCells
  46. Fitzgerald ML, Morris AL, Rhee JS, Andersson LP, Mendez AJ, Freeman MW. Naturally occurring mutations in the largest extracellular loops of ABCA1 can disrupt its direct interaction with apolipoprotein A-I. J Biol Chem. 2002 Sep 06; 277(36):33178-87. PMID: 12084722.
    Citations: 57     Fields:    Translation:HumansCells
  47. Fitzgerald ML, Moore KJ, Freeman MW. Nuclear hormone receptors and cholesterol trafficking: the orphans find a new home. J Mol Med (Berl). 2002 May; 80(5):271-81. PMID: 12021839.
    Citations: 13     Fields:    Translation:HumansAnimals
  48. Moore KJ, Fitzgerald ML, Freeman MW. Peroxisome proliferator-activated receptors in macrophage biology: friend or foe? Curr Opin Lipidol. 2001 Oct; 12(5):519-27. PMID: 11561171.
    Citations: 19     Fields:    Translation:HumansAnimalsCells
  49. Fitzgerald ML, Mendez AJ, Moore KJ, Andersson LP, Panjeton HA, Freeman MW. ATP-binding cassette transporter A1 contains an NH2-terminal signal anchor sequence that translocates the protein's first hydrophilic domain to the exoplasmic space. J Biol Chem. 2001 May 04; 276(18):15137-45. PMID: 11328826.
    Citations: 28     Fields:    Translation:Cells
  50. Moore KJ, Rosen ED, Fitzgerald ML, Randow F, Andersson LP, Altshuler D, Milstone DS, Mortensen RM, Spiegelman BM, Freeman MW. The role of PPAR-gamma in macrophage differentiation and cholesterol uptake. Nat Med. 2001 Jan; 7(1):41-7. PMID: 11135614.
    Citations: 142     Fields:    Translation:AnimalsCells
  51. Reed GL, Fitzgerald ML, Polgár J. Molecular mechanisms of platelet exocytosis: insights into the "secrete" life of thrombocytes. Blood. 2000 Nov 15; 96(10):3334-42. PMID: 11071625.
    Citations: 48     Fields:    Translation:HumansCells
  52. Fitzgerald ML, Moore KJ, Freeman MW, Reed GL. Lipopolysaccharide induces scavenger receptor A expression in mouse macrophages: a divergent response relative to human THP-1 monocyte/macrophages. J Immunol. 2000 Mar 01; 164(5):2692-700. PMID: 10679110.
    Citations: 25     Fields:    Translation:HumansAnimalsCells
  53. Fitzgerald ML, Wang Z, Park PW, Murphy G, Bernfield M. Shedding of syndecan-1 and -4 ectodomains is regulated by multiple signaling pathways and mediated by a TIMP-3-sensitive metalloproteinase. J Cell Biol. 2000 Feb 21; 148(4):811-24. PMID: 10684261; PMCID: PMC2169376.
    Citations: 146     Fields:    Translation:HumansAnimalsCells
  54. Park PW, Pier GB, Preston MJ, Goldberger O, Fitzgerald ML, Bernfield M. Syndecan-1 shedding is enhanced by LasA, a secreted virulence factor of Pseudomonas aeruginosa. J Biol Chem. 2000 Feb 04; 275(5):3057-64. PMID: 10652286.
    Citations: 43     Fields:    Translation:Cells
  55. Fitzgerald ML, Reed GL. Rab6 is phosphorylated in thrombin-activated platelets by a protein kinase C-dependent mechanism: effects on GTP/GDP binding and cellular distribution. Biochem J. 1999 Sep 01; 342 ( Pt 2):353-60. PMID: 10455022; PMCID: PMC1220472.
    Citations: 22     Fields:    Translation:HumansAnimalsCells
  56. Reed GL, Houng AK, Fitzgerald ML. Human platelets contain SNARE proteins and a Sec1p homologue that interacts with syntaxin 4 and is phosphorylated after thrombin activation: implications for platelet secretion. Blood. 1999 Apr 15; 93(8):2617-26. PMID: 10194441.
    Citations: 26     Fields:    Translation:HumansCells
  57. Bernfield M, Götte M, Park PW, Reizes O, Fitzgerald ML, Lincecum J, Zako M. Functions of cell surface heparan sulfate proteoglycans. Annu Rev Biochem. 1999; 68:729-77. PMID: 10872465.
    Citations: 859     Fields:    Translation:HumansAnimalsCells
  58. Kato M, Wang H, Kainulainen V, Fitzgerald ML, Ledbetter S, Ornitz DM, Bernfield M. Physiological degradation converts the soluble syndecan-1 ectodomain from an inhibitor to a potent activator of FGF-2. Nat Med. 1998 Jun; 4(6):691-7. PMID: 9623978.
    Citations: 91     Fields:    Translation:HumansCells
  59. Subramanian SV, Fitzgerald ML, Bernfield M. Regulated shedding of syndecan-1 and -4 ectodomains by thrombin and growth factor receptor activation. J Biol Chem. 1997 Jun 06; 272(23):14713-20. PMID: 9169435.
    Citations: 84     Fields:    Translation:HumansCells
  60. Vora AC, McCord M, Fitzgerald ML, Inman RB, Grandgenett DP. Efficient concerted integration of retrovirus-like DNA in vitro by avian myeloblastosis virus integrase. Nucleic Acids Res. 1994 Oct 25; 22(21):4454-61. PMID: 7971276; PMCID: PMC308479.
    Citations: 26     Fields:    Translation:Cells
  61. Fitzgerald ML, Grandgenett DP. Retroviral integration: in vitro host site selection by avian integrase. J Virol. 1994 Jul; 68(7):4314-21. PMID: 8207806; PMCID: PMC236354.
    Citations: 19     Fields:    Translation:Cells
  62. Stephens LE, Sonne JE, Fitzgerald ML, Damsky CH. Targeted deletion of beta 1 integrins in F9 embryonal carcinoma cells affects morphological differentiation but not tissue-specific gene expression. J Cell Biol. 1993 Dec; 123(6 Pt 1):1607-20. PMID: 7504677; PMCID: PMC2290911.
    Citations: 23     Fields:    Translation:AnimalsCells
  63. Grandgenett DP, Inman RB, Vora AC, Fitzgerald ML. Comparison of DNA binding and integration half-site selection by avian myeloblastosis virus integrase. J Virol. 1993 May; 67(5):2628-36. PMID: 8474165; PMCID: PMC237584.
    Citations: 15     Fields:    Translation:Cells
  64. Fitzgerald ML, Vora AC, Zeh WG, Grandgenett DP. Concerted integration of viral DNA termini by purified avian myeloblastosis virus integrase. J Virol. 1992 Nov; 66(11):6257-63. PMID: 1328665; PMCID: PMC240116.
    Citations: 36     Fields:    Translation:Cells
  65. Fitzgerald ML, Vora AC, Grandgenett DP. Development of an acid-soluble assay for measuring retrovirus integrase 3'-OH terminal nuclease activity. Anal Biochem. 1991 Jul; 196(1):19-23. PMID: 1888032.
    Citations: 8     Fields:    Translation:Cells
  66. Vora AC, Fitzgerald ML, Grandgenett DP. Removal of 3'-OH-terminal nucleotides from blunt-ended long terminal repeat termini by the avian retrovirus integration protein. J Virol. 1990 Nov; 64(11):5656-9. PMID: 2214031; PMCID: PMC248624.
    Citations: 39     Fields:    Translation:Cells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.