Harvard Catalyst Profiles

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A. Eden Evins, M.D.

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Biography
2001 - 2006
K23 Career Award
2010 - 2021
K24 Career Award

Overview

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Heffner JL, Evins AE, Russ C, Lawrence D, Ayers CR, McRae T, Aubin LS, Krishen A, West R, Anthenelli RM. Safety and efficacy of first-line smoking cessation pharmacotherapies in bipolar disorders: Subgroup analysis of a randomized clinical trial. J Affect Disord. 2019 Jun 03; 256:267-277. PMID: 31195244.
    Citations:    
  2. Gilman JM, Yücel MA, Pachas GN, Potter K, Levar N, Broos H, Manghis EM, Schuster RM, Evins AE. Delta-9-tetrahydrocannabinol intoxication is associated with increased prefrontal activation as assessed with functional near-infrared spectroscopy: A report of a potential biomarker of intoxication. Neuroimage. 2019 Aug 15; 197:575-585. PMID: 31075393.
    Citations:    
  3. Evins AE, Cather C, Daumit GL. Smoking cessation in people with serious mental illness. Lancet Psychiatry. 2019 Jul; 6(7):563-564. PMID: 30981756.
    Citations:    
  4. Anthenelli RM, Gaffney M, Benowitz NL, West R, McRae T, Russ C, Lawrence D, St Aubin L, Krishen A, Evins AE. Predictors of Neuropsychiatric Adverse Events with Smoking Cessation Medications in the Randomized Controlled EAGLES Trial. J Gen Intern Med. 2019 Jun; 34(6):862-870. PMID: 30847828.
    Citations:    
  5. Hrabovsky SM, Midya V, Lester C, Veldheer S, Yingst JM, Allen SI, Krebs NM, Liao J, Reinhart L, Modesto J, Evins AE, Richie JP, Muscat JE, Horn K, Foulds J. Effect of Cigarette Rod Length on Smokers Switching to SPECTRUM Cigarettes. Am J Health Behav. 2019 Mar 01; 43(2):380-392. PMID: 30808477.
    Citations:    
  6. Evins AE, Benowitz NL, West R, Russ C, McRae T, Lawrence D, Krishen A, St Aubin L, Maravic MC, Anthenelli RM. Neuropsychiatric Safety and Efficacy of Varenicline, Bupropion, and Nicotine Patch in Smokers With Psychotic, Anxiety, and Mood Disorders in the EAGLES Trial. J Clin Psychopharmacol. 2019 Mar/Apr; 39(2):108-116. PMID: 30811371.
    Citations:    
  7. Radoman M, Hoeppner SS, Schuster RM, Evins AE, Gilman JM. Marijuana use and major depressive disorder are additively associated with reduced verbal learning and altered cortical thickness. Cogn Affect Behav Neurosci. 2019 Feb 26. PMID: 30809764.
    Citations:    
  8. Dalcin AT, Jerome GJ, Appel LJ, Dickerson FB, Wang NY, Miller ER, Young DR, Charleston JB, Gennusa JV, Goldsholl S, Heller A, Evins AE, Cather C, McGinty EE, Crum RM, Daumit GL. Need for Cardiovascular Risk Reduction in Persons With Serious Mental Illness: Design of a Comprehensive Intervention. Front Psychiatry. 2018; 9:786. PMID: 30800079.
    Citations:    
  9. Schuster RM, Hareli M, Moser AD, Lowman K, Gilman J, Ulysse C, Schoenfeld D, Evins AE. Cross-domain correlates of cannabis use disorder severity among young adults. Addict Behav. 2019 Jun; 93:212-218. PMID: 30753972.
    Citations:    
  10. Schuster RM, Gilman J, Schoenfeld D, Evenden J, Hareli M, Ulysse C, Nip E, Hanly A, Zhang H, Evins AE. One Month of Cannabis Abstinence in Adolescents and Young Adults Is Associated With Improved Memory. J Clin Psychiatry. 2018 Oct 30; 79(6). PMID: 30408351.
    Citations:    Fields:    
  11. Otto MW, Pachas GN, Cather C, Hoeppner SS, Moshier SJ, Hearon BA, Ward HB, Laffer AB, Smits JAJ, Evins AE. A placebo-controlled randomized trial of D-cycloserine augmentation of cue exposure therapy for smoking cessation. Cogn Behav Ther. 2019 Jan; 48(1):65-76. PMID: 30111253.
    Citations:    Fields:    
  12. Schuster RM, Pachas GN, Stoeckel L, Cather C, Nadal M, Mischoulon D, Schoenfeld DA, Zhang H, Ulysse C, Dodds EB, Sobolewski S, Hudziak V, Hanly A, Fava M, Evins AE. Phase IIb Trial of an a7 Nicotinic Receptor Partial Agonist With and Without Nicotine Patch for Withdrawal-Associated Cognitive Deficits and Tobacco Abstinence. J Clin Psychopharmacol. 2018 Aug; 38(4):307-316. PMID: 29912798.
    Citations:    Fields:    Translation:HumansCTClinical Trials
  13. Allen SI, Wasserman E, Veldheer S, Yingst J, Hrabovsky S, Liao J, Krebs NM, Horn K, Reinhart L, Modesto J, Putt K, Evins AE, Muscat JE, Richie JP, Foulds J. Characteristics of adult cigarette smokers who "relight" and the effects of exposure to tobacco smoke constituents. Nicotine Tob Res. 2018 Jul 04. PMID: 29982710.
    Citations:    Fields:    
  14. Moran LV, Stoeckel LE, Wang K, Caine CE, Villafuerte R, Calderon V, Baker JT, Ongur D, Janes AC, Pizzagalli DA, Eden Evins A. Nicotine Increases Activation to Anticipatory Valence Cues in Anterior Insula and Striatum. Nicotine Tob Res. 2018 06 07; 20(7):851-858. PMID: 29059451.
    Citations:    Fields:    
  15. West R, Evins AE, Benowitz NL, Russ C, McRae T, Lawrence D, St Aubin L, Krishen A, Maravic MC, Anthenelli RM. Factors associated with the efficacy of smoking cessation treatments and predictors of smoking abstinence in EAGLES. Addiction. 2018 Aug; 113(8):1507-1516. PMID: 29508470.
    Citations: 2     Fields:    
  16. Evins AE, Kelly JF. A Call to Action for Treatment of Comorbid Tobacco and Alcohol Dependence. JAMA Psychiatry. 2018 Feb 01; 75(2):121-122. PMID: 29261821.
    Citations:    Fields:    
  17. Gilman JM, Radoman M, Schuster RM, Pachas G, Azzouz N, Fava M, Evins AE. Anterior insula activation during inhibition to smoking cues is associated with ability to maintain tobacco abstinence. Addict Behav Rep. 2018 Jun; 7:40-46. PMID: 29450255.
    Citations:    
  18. Veldheer S, Midya V, Lester C, Liao J, Yingst J, Hrabovsky S, Allen SI, Krebs NM, Reinhart L, Evins AE, Horn K, Richie J, Muscat J, Foulds J. Acceptability of SPECTRUM Research Cigarettes among Participants in Trials of Reduced Nicotine Content Cigarettes. Tob Regul Sci. 2018 Jan; 4(1):573-585. PMID: 30662929.
    Citations:    
  19. Moran LV, Stoeckel LE, Wang K, Caine CE, Villafuerte R, Calderon V, Baker JT, Ongur D, Janes AC, Evins AE, Pizzagalli DA. Nicotine-induced activation of caudate and anterior cingulate cortex in response to errors in schizophrenia. Psychopharmacology (Berl). 2018 03; 235(3):789-802. PMID: 29181816.
    Citations:    Fields:    Translation:Humans
  20. Janes AC, Gilman JM, Frederick BB, Radoman M, Pachas G, Fava M, Evins AE. Salience network coupling is linked to both tobacco smoking and symptoms of attention deficit hyperactivity disorder (ADHD). Drug Alcohol Depend. 2018 01 01; 182:93-97. PMID: 29175464.
    Citations: 1     Fields:    Translation:HumansCTClinical Trials
  21. Keles HO, Radoman M, Pachas GN, Evins AE, Gilman JM. Using Functional Near-Infrared Spectroscopy to Measure Effects of Delta 9-Tetrahydrocannabinol on Prefrontal Activity and Working Memory in Cannabis Users. Front Hum Neurosci. 2017; 11:488. PMID: 29066964.
    Citations:    
  22. Holsen LM, Davidson P, Cerit H, Hye T, Moondra P, Haimovici F, Sogg S, Shikora S, Goldstein JM, Evins AE, Stoeckel LE. Neural predictors of 12-month weight loss outcomes following bariatric surgery. Int J Obes (Lond). 2018 04; 42(4):785-793. PMID: 28894291.
    Citations: 2     Fields:    
  23. Janes AC, Gilman JM, Radoman M, Pachas G, Fava M, Evins AE. Revisiting the role of the insula and smoking cue-reactivity in relapse: A replication and extension of neuroimaging findings. Drug Alcohol Depend. 2017 10 01; 179:8-12. PMID: 28735078.
    Citations: 2     Fields:    Translation:Humans
  24. Cather C, Pachas GN, Cieslak KM, Evins AE. Achieving Smoking Cessation in Individuals with Schizophrenia: Special Considerations. CNS Drugs. 2017 Jun; 31(6):471-481. PMID: 28550660.
    Citations: 4     Fields:    Translation:Humans
  25. Cather C, Hoeppner S, Pachas G, Pratt S, Achtyes E, Cieslak KM, Evins AE. Improved Depressive Symptoms in Adults with Schizophrenia During a Smoking Cessation Attempt with Varenicline and Behavioral Therapy. J Dual Diagn. 2017 Jul-Sep; 13(3):168-178. PMID: 28414583.
    Citations:    Fields:    Translation:HumansCTClinical Trials
  26. Evins AE, Korhonen T, Kinnunen TH, Kaprio J. Prospective association between tobacco smoking and death by suicide: a competing risks hazard analysis in a large twin cohort with 35-year follow-up. Psychol Med. 2017 Sep; 47(12):2143-2154. PMID: 28399944.
    Citations: 1     Fields:    Translation:Humans
  27. Schuster RM, Fontaine M, Nip E, Zhang H, Hanly A, Evins AE. Prolonged cannabis withdrawal in young adults with lifetime psychiatric illness. Prev Med. 2017 11; 104:40-45. PMID: 28242263.
    Citations: 1     Fields:    Translation:HumansAnimals
  28. Schuster RM, Cather C, Pachas GN, Zhang H, Cieslak KM, Hoeppner SS, Schoenfeld D, Evins AE. Predictors of tobacco abstinence in outpatient smokers with schizophrenia or bipolar disorder treated with varenicline and cognitive behavioral smoking cessation therapy. Addict Behav. 2017 08; 71:89-95. PMID: 28285208.
    Citations: 1     Fields:    Translation:Humans
  29. Allen SI, Foulds J, Pachas GN, Veldheer S, Cather C, Azzouz N, Hrabovsky S, Hameed A, Yingst J, Hammett E, Modesto J, Krebs NM, Zhu J, Liao J, Muscat JE, Richie J, Evins AE. A two-site, two-arm, 34-week, double-blind, parallel-group, randomized controlled trial of reduced nicotine cigarettes in smokers with mood and/or anxiety disorders: trial design and protocol. BMC Public Health. 2017 01 19; 17(1):100. PMID: 28103841.
    Citations: 1     Fields:    Translation:HumansAnimals
  30. Evins AE, Hoeppner SS, Schoenfeld DA, Hoeppner BB, Cather C, Pachas GN, Cieslak KM, Maravic MC. Maintenance pharmacotherapy normalizes the relapse curve in recently abstinent tobacco smokers with schizophrenia and bipolar disorder. Schizophr Res. 2017 05; 183:124-129. PMID: 27956009.
    Citations: 1     Fields:    Translation:Humans
  31. Schuster RM, Hanly A, Gilman J, Budney A, Vandrey R, Evins AE. A contingency management method for 30-days abstinence in non-treatment seeking young adult cannabis users. Drug Alcohol Depend. 2016 Oct 01; 167:199-206. PMID: 27590742.
    Citations: 3     Fields:    Translation:Humans
  32. Gilman JM, Schuster RM, Curran MT, Calderon V, van der Kouwe A, Evins AE. Neural mechanisms of sensitivity to peer information in young adult cannabis users. Cogn Affect Behav Neurosci. 2016 08; 16(4):646-61. PMID: 27068178.
    Citations: 3     Fields:    Translation:Humans
  33. Anthenelli RM, Benowitz NL, West R, St Aubin L, McRae T, Lawrence D, Ascher J, Russ C, Krishen A, Evins AE. Neuropsychiatric safety and efficacy of varenicline, bupropion, and nicotine patch in smokers with and without psychiatric disorders (EAGLES): a double-blind, randomised, placebo-controlled clinical trial. Lancet. 2016 Jun 18; 387(10037):2507-20. PMID: 27116918.
    Citations: 52     Fields:    Translation:Humans
  34. Schuster RM, Hoeppner SS, Evins AE, Gilman JM. Early onset marijuana use is associated with learning inefficiencies. Neuropsychology. 2016 05; 30(4):405-15. PMID: 26986749.
    Citations: 3     Fields:    Translation:HumansAnimals
  35. Volkow ND, Swanson JM, Evins AE, DeLisi LE, Meier MH, Gonzalez R, Bloomfield MA, Curran HV, Baler R. Effects of Cannabis Use on Human Behavior, Including Cognition, Motivation, and Psychosis: A Review. JAMA Psychiatry. 2016 Mar; 73(3):292-7. PMID: 26842658.
    Citations: 52     Fields:    Translation:HumansAnimals
  36. Thorndike AN, Achtyes ED, Cather C, Pratt S, Pachas GN, Hoeppner SS, Evins AE. Weight gain and 10-year cardiovascular risk with sustained tobacco abstinence in smokers with serious mental illness: a subgroup analysis of a randomized trial. J Clin Psychiatry. 2016 Mar; 77(3):e320-6. PMID: 27046320.
    Citations: 2     Fields:    Translation:Humans
  37. Gilman JM, Curran MT, Calderon V, Schuster RM, Evins AE. Altered Neural Processing to Social Exclusion in Young Adult Marijuana Users. Biol Psychiatry Cogn Neurosci Neuroimaging. 2016 Mar 01; 1(2):152-159. PMID: 26977454.
    Citations: 1     Fields:    
  38. Otto MW, Kredlow MA, Smits JAJ, Hofmann SG, Tolin DF, de Kleine RA, van Minnen A, Evins AE, Pollack MH. Enhancement of Psychosocial Treatment With D-Cycloserine: Models, Moderators, and Future Directions. Biol Psychiatry. 2016 08 15; 80(4):274-283. PMID: 26520240.
    Citations: 8     Fields:    Translation:Humans
  39. Evins AE, Cather C. Effective Cessation Strategies for Smokers with Schizophrenia. Int Rev Neurobiol. 2015; 124:133-47. PMID: 26472528.
    Citations: 3     Fields:    Translation:Humans
  40. Haney M, Evins AE. Does Cannabis Cause, Exacerbate or Ameliorate Psychiatric Disorders? An Oversimplified Debate Discussed. Neuropsychopharmacology. 2016 Jan; 41(2):393-401. PMID: 26286840.
    Citations: 7     Fields:    Translation:HumansAnimals
  41. Pachas GN, Gilman J, Orr SP, Hoeppner B, Carlini SV, Grasser EB, Loebl T, Nino J, Pitman RK, Evins AE. Erratum to: Single dose propranolol does not affect physiologic or emotional reactivity to smoking cues. Psychopharmacology (Berl). 2015 Jun; 232(11):2029. PMID: 25877745.
    Citations: 1     Fields:    
  42. Stoeckel LE, Chai XJ, Zhang J, Whitfield-Gabrieli S, Evins AE. Lower gray matter density and functional connectivity in the anterior insula in smokers compared with never smokers. Addict Biol. 2016 07; 21(4):972-81. PMID: 25990865.
    Citations: 5     Fields:    Translation:Humans
  43. Gilman JM, Treadway MT, Curran MT, Calderon V, Evins AE. Effect of social influence on effort-allocation for monetary rewards. PLoS One. 2015; 10(5):e0126656. PMID: 25961725.
    Citations: 4     Fields:    Translation:Humans
  44. Wang R, Schoenfeld DA, Hoeppner B, Evins AE. Detecting treatment-covariate interactions using permutation methods. Stat Med. 2015 May 30; 34(12):2035-47. PMID: 25736915.
    Citations: 2     Fields:    Translation:Humans
  45. Evins AE, Cather C, Laffer A. Treatment of tobacco use disorders in smokers with serious mental illness: toward clinical best practices. Harv Rev Psychiatry. 2015 Mar-Apr; 23(2):90-8. PMID: 25747922.
    Citations: 10     Fields:    Translation:Humans
  46. Janes AC, Pedrelli P, Whitton AE, Pechtel P, Douglas S, Martinson MA, Huz I, Fava M, Pizzagalli DA, Evins AE. Reward Responsiveness Varies by Smoking Status in Women with a History of Major Depressive Disorder. Neuropsychopharmacology. 2015 Jul; 40(8):1940-6. PMID: 25662839.
    Citations: 7     Fields:    Translation:Humans
  47. Gilman JM, Calderon V, Curran MT, Evins AE. Young adult cannabis users report greater propensity for risk-taking only in non-monetary domains. Drug Alcohol Depend. 2015 Feb 01; 147:26-31. PMID: 25577478.
    Citations: 4     Fields:    Translation:Humans
  48. Pachas GN, Gilman J, Orr SP, Hoeppner B, Carlini SV, Grasser EB, Loebl T, Nino J, Pitman RK, Evins AE. Single dose propranolol does not affect physiologic or emotional reactivity to smoking cues. Psychopharmacology (Berl). 2015 May; 232(9):1619-28. PMID: 25413896.
    Citations: 10     Fields:    Translation:Humans
  49. Evins AE, Hong LE, Kelly DL. T. Kishi and N. Iwata: Varenicline for smoking cessation in people with schizophrenia: systematic review meta-analysis. Eur Arch Psychiatry Clin Neurosci. 2015 Apr; 265(3):269-70. PMID: 25377170.
    Citations: 1     Fields:    Translation:Humans
  50. Stoeckel LE, Palley LS, Gollub RL, Niemi SM, Evins AE. Patterns of brain activation when mothers view their own child and dog: an fMRI study. PLoS One. 2014; 9(10):e107205. PMID: 25279788.
    Citations: 9     Fields:    Translation:HumansAnimals
  51. Roh SW, Hoeppner SS, Stoeckel LE, Evins AE. Sy22-5nicotine and cognition in schizophrenia. Alcohol Alcohol. 2014 Sep; 49 Suppl 1:i21. PMID: 25221053.
    Citations:    
  52. Stoeckel LE, Garrison KA, Ghosh S, Wighton P, Hanlon CA, Gilman JM, Greer S, Turk-Browne NB, deBettencourt MT, Scheinost D, Craddock C, Thompson T, Calderon V, Bauer CC, George M, Breiter HC, Whitfield-Gabrieli S, Gabrieli JD, LaConte SM, Hirshberg L, Brewer JA, Hampson M, Van Der Kouwe A, Mackey S, Evins AE. Optimizing real time fMRI neurofeedback for therapeutic discovery and development. Neuroimage Clin. 2014; 5:245-55. PMID: 25161891.
    Citations: 34     Fields:    Translation:Humans
  53. Gilman JM, Curran MT, Calderon V, Stoeckel LE, Evins AE. Impulsive social influence increases impulsive choices on a temporal discounting task in young adults. PLoS One. 2014; 9(7):e101570. PMID: 24988440.
    Citations: 5     Fields:    Translation:Humans
  54. Schuman-Olivier Z, Hoeppner BB, Evins AE, Brewer JA. Finding the right match: mindfulness training may potentiate the therapeutic effect of nonjudgment of inner experience on smoking cessation. Subst Use Misuse. 2014 Apr; 49(5):586-94. PMID: 24611853.
    Citations: 2     Fields:    Translation:Humans
  55. Barake M, Evins AE, Stoeckel L, Pachas GN, Nachtigall LB, Miller KK, Biller BM, Tritos NA, Klibanski A. Investigation of impulsivity in patients on dopamine agonist therapy for hyperprolactinemia: a pilot study. Pituitary. 2014 Apr; 17(2):150-6. PMID: 23504371.
    Citations: 6     Fields:    Translation:Humans
  56. David SP, Chu IM, Lancaster T, Stead LF, Evins AE, Prochaska JJ. Systematic review and meta-analysis of opioid antagonists for smoking cessation. BMJ Open. 2014 Mar 14; 4(3):e004393. PMID: 24633528.
    Citations: 7     Fields:    Translation:Humans
  57. Evins AE, Cather C, Pratt SA, Pachas GN, Hoeppner SS, Goff DC, Achtyes ED, Ayer D, Schoenfeld DA. Maintenance treatment with varenicline for smoking cessation in patients with schizophrenia and bipolar disorder: a randomized clinical trial. JAMA. 2014 Jan 08; 311(2):145-54. PMID: 24399553.
    Citations: 47     Fields:    Translation:Humans
  58. Evins AE. Reassessing the safety of varenicline. Am J Psychiatry. 2013 Dec; 170(12):1385-7. PMID: 24306334.
    Citations: 7     Fields:    Translation:Humans
  59. Roh S, Hoeppner SS, Schoenfeld D, Fullerton CA, Stoeckel LE, Evins AE. Acute effects of mecamylamine and varenicline on cognitive performance in non-smokers with and without schizophrenia. Psychopharmacology (Berl). 2014 Feb; 231(4):765-75. PMID: 24114425.
    Citations: 6     Fields:    Translation:Humans
  60. David SP, Lancaster T, Stead LF, Evins AE, Prochaska JJ. Opioid antagonists for smoking cessation. Cochrane Database Syst Rev. 2013 Jun 06; (6):CD003086. PMID: 23744347.
    Citations: 13     Fields:    Translation:Humans
  61. Evins AE, Green AI, Kane JM, Murray RM. Does using marijuana increase the risk for developing schizophrenia? J Clin Psychiatry. 2013 Apr; 74(4):e08. PMID: 23656852.
    Citations: 2     Fields:    Translation:HumansAnimals
  62. Cather C, Dyer MA, Burrell HA, Hoeppner B, Goff DC, Evins AE. An Open Trial of Relapse Prevention Therapy for Smokers With Schizophrenia. J Dual Diagn. 2013; 9(1):87-93. PMID: 23750123.
    Citations: 8     Fields:    
  63. Witte J, Bentley K, Evins AE, Clain AJ, Baer L, Pedrelli P, Fava M, Mischoulon D. A randomized, controlled, pilot study of acamprosate added to escitalopram in adults with major depressive disorder and alcohol use disorder. J Clin Psychopharmacol. 2012 Dec; 32(6):787-96. PMID: 23131884.
    Citations: 4     Fields:    Translation:Humans
  64. Evins AE, Green AI, Kane JM, Murray RM. The effect of marijuana use on the risk for schizophrenia. J Clin Psychiatry. 2012 Nov; 73(11):1463-8. PMID: 23218162.
    Citations: 4     Fields:    Translation:HumansAnimals
  65. Pachas GN, Cather C, Pratt SA, Hoeppner B, Nino J, Carlini SV, Achtyes ED, Lando H, Mueser KT, Rigotti NA, Goff DC, Evins AE. Varenicline for Smoking Cessation in Schizophrenia: Safety and Effectiveness in a 12-Week, Open-Label Trial. J Dual Diagn. 2012; 8(2):117-125. PMID: 22888309.
    Citations: 17     Fields:    
  66. Roh S, Evins AE. Possible role of nicotine for the treatment of mild cognitive impairment. Expert Rev Neurother. 2012 May; 12(5):531-3. PMID: 22550981.
    Citations:    Fields:    
  67. Evins AE, Pachas G, Mischoulon D, Urbanoski K, Carlini S, Sousa J, Bentley K, Rigotti NA, Nino-Gomez J, Loebl T, Janes AC, Kaufman MJ, Fava M. A double-blind, placebo-controlled trial of the NMDA glycine site antagonist, GW468816, for prevention of relapse to smoking in females. J Clin Psychopharmacol. 2011 Oct; 31(5):597-602. PMID: 21869693.
    Citations: 3     Fields:    Translation:HumansPHPublic Health
  68. Janes AC, Smoller JW, David SP, Frederick BD, Haddad S, Basu A, Fava M, Evins AE, Kaufman MJ. Association between CHRNA5 genetic variation at rs16969968 and brain reactivity to smoking images in nicotine dependent women. Drug Alcohol Depend. 2012 Jan 01; 120(1-3):7-13. PMID: 21764527.
    Citations: 16     Fields:    Translation:Humans
  69. Dutra SJ, Stoeckel LE, Carlini SV, Pizzagalli DA, Evins AE. Varenicline as a smoking cessation aid in schizophrenia: effects on smoking behavior and reward sensitivity. Psychopharmacology (Berl). 2012 Jan; 219(1):25-34. PMID: 21695488.
    Citations: 12     Fields:    Translation:Humans
  70. Mashhoon Y, Janes AC, Jensen JE, Prescot AP, Pachas G, Renshaw PF, Fava M, Evins AE, Kaufman MJ. Anterior cingulate proton spectroscopy glutamate levels differ as a function of smoking cessation outcome. Prog Neuropsychopharmacol Biol Psychiatry. 2011 Aug 15; 35(7):1709-13. PMID: 21616118.
    Citations: 11     Fields:    Translation:Humans
  71. Iovieno N, Tedeschini E, Bentley KH, Evins AE, Papakostas GI. Antidepressants for major depressive disorder and dysthymic disorder in patients with comorbid alcohol use disorders: a meta-analysis of placebo-controlled randomized trials. J Clin Psychiatry. 2011 Aug; 72(8):1144-51. PMID: 21536001.
    Citations: 15     Fields:    Translation:Humans
  72. Weiner E, Ball MP, Buchholz AS, Gold JM, Evins AE, McMahon RP, Buchanan RW. Bupropion sustained release added to group support for smoking cessation in schizophrenia: a new randomized trial and a meta-analysis. J Clin Psychiatry. 2012 Jan; 73(1):95-102. PMID: 21535998.
    Citations: 14     Fields:    Translation:Humans
  73. Evins AE. Review: bupropion increases abstinence from smoking without affecting mental state in people with schizophrenia. Evid Based Ment Health. 2010 Nov; 13(4):120. PMID: 21036982.
    Citations: 3     Fields:    
  74. Janes AC, Pizzagalli DA, Richardt S, Frederick Bde B, Holmes AJ, Sousa J, Fava M, Evins AE, Kaufman MJ. Neural substrates of attentional bias for smoking-related cues: an FMRI study. Neuropsychopharmacology. 2010 Nov; 35(12):2339-45. PMID: 20703221.
    Citations: 33     Fields:    Translation:Humans
  75. Janes AC, Pizzagalli DA, Richardt S, deB Frederick B, Chuzi S, Pachas G, Culhane MA, Holmes AJ, Fava M, Evins AE, Kaufman MJ. Brain reactivity to smoking cues prior to smoking cessation predicts ability to maintain tobacco abstinence. Biol Psychiatry. 2010 Apr 15; 67(8):722-9. PMID: 20172508.
    Citations: 142     Fields:    Translation:Humans
  76. Freudenreich O, Brockman MA, Henderson DC, Evins AE, Fan X, Walsh JP, Goff DC. Analysis of peripheral immune activation in schizophrenia using quantitative reverse-transcription polymerase chain reaction (RT-PCR). Psychiatry Res. 2010 Apr 30; 176(2-3):99-102. PMID: 20132993.
    Citations: 3     Fields:    Translation:Humans
  77. Henderson DC, Sharma B, Fan X, Copeland PM, Borba CP, Freudenreich O, Cather C, Evins AE, Goff DC. Dietary saturated fat intake and glucose metabolism impairments in nondiabetic, nonobese patients with schizophrenia on clozapine or risperidone. Ann Clin Psychiatry. 2010 Feb; 22(1):33-42. PMID: 20196981.
    Citations: 5     Fields:    Translation:Humans
  78. Janes AC, Frederick Bd, Richardt S, Burbridge C, Merlo-Pich E, Renshaw PF, Evins AE, Fava M, Kaufman MJ. Brain fMRI reactivity to smoking-related images before and during extended smoking abstinence. Exp Clin Psychopharmacol. 2009 Dec; 17(6):365-73. PMID: 19968401.
    Citations: 23     Fields:    Translation:Humans
  79. Freudenreich O, Henderson DC, Macklin EA, Evins AE, Fan X, Cather C, Walsh JP, Goff DC. Modafinil for clozapine-treated schizophrenia patients: a double-blind, placebo-controlled pilot trial. J Clin Psychiatry. 2009 Dec; 70(12):1674-80. PMID: 19689921.
    Citations: 14     Fields:    Translation:Humans
  80. Santesso DL, Evins AE, Frank MJ, Schetter EC, Bogdan R, Pizzagalli DA. Single dose of a dopamine agonist impairs reinforcement learning in humans: evidence from event-related potentials and computational modeling of striatal-cortical function. Hum Brain Mapp. 2009 Jul; 30(7):1963-76. PMID: 18726908.
    Citations: 39     Fields:    Translation:Humans
  81. Henderson DC, Fan X, Sharma B, Copeland PM, Borba CP, Freudenreich O, Cather C, Evins AE, Goff DC. Waist circumference is the best anthropometric predictor for insulin resistance in nondiabetic patients with schizophrenia treated with clozapine but not olanzapine. J Psychiatr Pract. 2009 Jul; 15(4):251-61. PMID: 19625881.
    Citations: 3     Fields:    Translation:Humans
  82. Kaufman MJ, Prescot AP, Ongur D, Evins AE, Barros TL, Medeiros CL, Covell J, Wang L, Fava M, Renshaw PF. Oral glycine administration increases brain glycine/creatine ratios in men: a proton magnetic resonance spectroscopy study. Psychiatry Res. 2009 Aug 30; 173(2):143-9. PMID: 19556112.
    Citations: 7     Fields:    Translation:HumansCTClinical Trials
  83. Henderson DC, Fan X, Copeland PM, Sharma B, Borba CP, Boxill R, Freudenreich O, Cather C, Evins AE, Goff DC. Aripiprazole added to overweight and obese olanzapine-treated schizophrenia patients. J Clin Psychopharmacol. 2009 Apr; 29(2):165-9. PMID: 19512978.
    Citations: 10     Fields:    Translation:Humans
  84. Henderson DC, Fan X, Copeland PM, Sharma B, Borba CP, Forstbauer SI, Miley K, Boxill R, Freudenreich O, Cather C, Evins AE, Goff DC. Ziprasidone as an adjuvant for clozapine- or olanzapine-associated medical morbidity in chronic schizophrenia. Hum Psychopharmacol. 2009 Apr; 24(3):225-32. PMID: 19283774.
    Citations: 5     Fields:    Translation:HumansCTClinical Trials
  85. Evins AE, Culhane MA, Alpert JE, Pava J, Liese BS, Farabaugh A, Fava M. A controlled trial of bupropion added to nicotine patch and behavioral therapy for smoking cessation in adults with unipolar depressive disorders. J Clin Psychopharmacol. 2008 Dec; 28(6):660-6. PMID: 19011435.
    Citations: 22     Fields:    Translation:Humans
  86. Culhane MA, Schoenfeld DA, Barr RS, Cather C, Deckersbach T, Freudenreich O, Goff DC, Rigotti NA, Evins AE. Predictors of early abstinence in smokers with schizophrenia. J Clin Psychiatry. 2008 Nov; 69(11):1743-50. PMID: 19026259.
    Citations: 17     Fields:    Translation:Humans
  87. Makris N, Gasic GP, Kennedy DN, Hodge SM, Kaiser JR, Lee MJ, Kim BW, Blood AJ, Evins AE, Seidman LJ, Iosifescu DV, Lee S, Baxter C, Perlis RH, Smoller JW, Fava M, Breiter HC. Cortical thickness abnormalities in cocaine addiction--a reflection of both drug use and a pre-existing disposition to drug abuse? Neuron. 2008 Oct 09; 60(1):174-88. PMID: 18940597.
    Citations: 44     Fields:    Translation:Humans
  88. Goff DC, Cather C, Gottlieb JD, Evins AE, Walsh J, Raeke L, Otto MW, Schoenfeld D, Green MF. Once-weekly D-cycloserine effects on negative symptoms and cognition in schizophrenia: an exploratory study. Schizophr Res. 2008 Dec; 106(2-3):320-7. PMID: 18799288.
    Citations: 38     Fields:    Translation:Humans
  89. Goff DC, Cather C, Freudenreich O, Henderson DC, Evins AE, Culhane MA, Walsh JP. A placebo-controlled study of sildenafil effects on cognition in schizophrenia. Psychopharmacology (Berl). 2009 Jan; 202(1-3):411-7. PMID: 18716761.
    Citations: 14     Fields:    Translation:Humans
  90. Jubelt LE, Barr RS, Goff DC, Logvinenko T, Weiss AP, Evins AE. Effects of transdermal nicotine on episodic memory in non-smokers with and without schizophrenia. Psychopharmacology (Berl). 2008 Jul; 199(1):89-98. PMID: 18548234.
    Citations: 34     Fields:    Translation:Humans
  91. Evins AE, Goff DC. Varenicline treatment for smokers with schizophrenia: a case series. J Clin Psychiatry. 2008 Jun; 69(6):1016. PMID: 18683999.
    Citations: 19     Fields:    Translation:Humans
  92. Fan X, Henderson DC, Nguyen DD, Cather C, Freudenreich O, Evins AE, Borba CP, Goff DC. Posttraumatic stress disorder, cognitive function and quality of life in patients with schizophrenia. Psychiatry Res. 2008 May 30; 159(1-2):140-6. PMID: 18423611.
    Citations: 11     Fields:    Translation:Humans
  93. Dyer MA, Freudenreich O, Culhane MA, Pachas GN, Deckersbach T, Murphy E, Goff DC, Evins AE. High-dose galantamine augmentation inferior to placebo on attention, inhibitory control and working memory performance in nonsmokers with schizophrenia. Schizophr Res. 2008 Jul; 102(1-3):88-95. PMID: 18325740.
    Citations: 17     Fields:    Translation:Humans
  94. Loebl T, Angarita GA, Pachas GN, Huang KL, Lee SH, Nino J, Logvinenko T, Culhane MA, Evins AE. A randomized, double-blind, placebo-controlled trial of long-acting risperidone in cocaine-dependent men. J Clin Psychiatry. 2008 Mar; 69(3):480-6. PMID: 18294021.
    Citations: 9     Fields:    Translation:Humans
  95. Gelenberg AJ, de Leon J, Evins AE, Parks JJ, Rigotti NA. Smoking cessation in patients with psychiatric disorders. Prim Care Companion J Clin Psychiatry. 2008; 10(1):52-8. PMID: 18311422.
    Citations: 6     
  96. David SP, Strong DR, Munafò MR, Brown RA, Lloyd-Richardson EE, Wileyto PE, Evins AE, Shields PG, Lerman C, Niaura R. Bupropion efficacy for smoking cessation is influenced by the DRD2 Taq1A polymorphism: analysis of pooled data from two clinical trials. Nicotine Tob Res. 2007 12; 9(12):1251-7. PMID: 18058343.
    Citations: 33     Fields:    Translation:Humans
  97. Barr RS, Pizzagalli DA, Culhane MA, Goff DC, Evins AE. A single dose of nicotine enhances reward responsiveness in nonsmokers: implications for development of dependence. Biol Psychiatry. 2008 Jun 01; 63(11):1061-5. PMID: 17976537.
    Citations: 55     Fields:    Translation:Humans
  98. Pizzagalli DA, Evins AE, Schetter EC, Frank MJ, Pajtas PE, Santesso DL, Culhane M. Single dose of a dopamine agonist impairs reinforcement learning in humans: behavioral evidence from a laboratory-based measure of reward responsiveness. Psychopharmacology (Berl). 2008 Feb; 196(2):221-32. PMID: 17909750.
    Citations: 70     Fields:    Translation:Humans
  99. Gelenberg AJ, de Leon J, Evins AE, Parks JJ, Rigotti NA. Smoking cessation in patients with psychiatric disorders. J Clin Psychiatry. 2007 Sep; 68(9):1404-10. PMID: 17915980.
    Citations: 1     Fields:    Translation:Humans
  100. Evins AE, Cather C, Culhane MA, Birnbaum A, Horowitz J, Hsieh E, Freudenreich O, Henderson DC, Schoenfeld DA, Rigotti NA, Goff DC. A 12-week double-blind, placebo-controlled study of bupropion sr added to high-dose dual nicotine replacement therapy for smoking cessation or reduction in schizophrenia. J Clin Psychopharmacol. 2007 Aug; 27(4):380-6. PMID: 17632223.
    Citations: 48     Fields:    Translation:Humans
  101. Fan X, Henderson DC, Chiang E, Briggs LB, Freudenreich O, Evins AE, Cather C, Goff DC. Sexual functioning, psychopathology and quality of life in patients with schizophrenia. Schizophr Res. 2007 Aug; 94(1-3):119-27. PMID: 17590315.
    Citations: 4     Fields:    Translation:Humans
  102. Barr RS, Culhane MA, Jubelt LE, Mufti RS, Dyer MA, Weiss AP, Deckersbach T, Kelly JF, Freudenreich O, Goff DC, Evins AE. The effects of transdermal nicotine on cognition in nonsmokers with schizophrenia and nonpsychiatric controls. Neuropsychopharmacology. 2008 Feb; 33(3):480-90. PMID: 17443126.
    Citations: 84     Fields:    Translation:Humans
  103. Henderson DC, Fan X, Copeland PM, Borba CP, Daley TB, Nguyen DD, Zhang H, Hayden D, Freudenreich O, Cather C, Evins AE, Goff DC. A double-blind, placebo-controlled trial of sibutramine for clozapine-associated weight gain. Acta Psychiatr Scand. 2007 Feb; 115(2):101-5. PMID: 17244173.
    Citations: 15     Fields:    Translation:Humans
  104. David S, Lancaster T, Stead LF, Evins AE. Opioid antagonists for smoking cessation. Cochrane Database Syst Rev. 2006 Oct 18; (4):CD003086. PMID: 17054160.
    Citations: 16     Fields:    Translation:Humans
  105. Henderson DC, Copeland PM, Borba CP, Daley TB, Nguyen DD, Cagliero E, Evins AE, Zhang H, Hayden DL, Freudenreich O, Cather C, Schoenfeld DA, Goff DC. Glucose metabolism in patients with schizophrenia treated with olanzapine or quetiapine: a frequently sampled intravenous glucose tolerance test and minimal model analysis. J Clin Psychiatry. 2006 May; 67(5):789-97. PMID: 16841629.
    Citations: 12     Fields:    Translation:Humans
  106. Eden Evins A, Demopulos C, Yovel I, Culhane M, Ogutha J, Grandin LD, Nierenberg AA, Sachs GS. Inositol augmentation of lithium or valproate for bipolar depression. Bipolar Disord. 2006 Apr; 8(2):168-74. PMID: 16542187.
    Citations: 9     Fields:    Translation:Humans
  107. Eden Evins A, Demopulos C, Nierenberg A, Culhane MA, Eisner L, Sachs G. A double-blind, placebo-controlled trial of adjunctive donepezil in treatment-resistant mania. Bipolar Disord. 2006 Feb; 8(1):75-80. PMID: 16411983.
    Citations: 9     Fields:    Translation:Humans
  108. Henderson DC, Kunkel L, Nguyen DD, Borba CP, Daley TB, Louie PM, Freudenreich O, Cather C, Evins AE, Goff DC. An exploratory open-label trial of aripiprazole as an adjuvant to clozapine therapy in chronic schizophrenia. Acta Psychiatr Scand. 2006 Feb; 113(2):142-7. PMID: 16423166.
    Citations: 22     Fields:    Translation:HumansCTClinical Trials
  109. Freudenreich O, Herz L, Deckersbach T, Evins AE, Henderson DC, Cather C, Goff DC. Added donepezil for stable schizophrenia: a double-blind, placebo-controlled trial. Psychopharmacology (Berl). 2005 Sep; 181(2):358-63. PMID: 15778880.
    Citations: 20     Fields:    Translation:Humans
  110. Henderson DC, Nguyen DD, Copeland PM, Hayden DL, Borba CP, Louie PM, Freudenreich O, Evins AE, Cather C, Goff DC. Clozapine, diabetes mellitus, hyperlipidemia, and cardiovascular risks and mortality: results of a 10-year naturalistic study. J Clin Psychiatry. 2005 Sep; 66(9):1116-21. PMID: 16187768.
    Citations: 33     Fields:    Translation:Humans
  111. Evins AE, Deckersbach T, Cather C, Freudenreich O, Culhane MA, Henderson DC, Green MF, Schoenfeld DA, Rigotti NA, Goff DC. Independent effects of tobacco abstinence and bupropion on cognitive function in schizophrenia. J Clin Psychiatry. 2005 Sep; 66(9):1184-90. PMID: 16187778.
    Citations: 17     Fields:    Translation:Humans
  112. Evins AE, Cather C, Deckersbach T, Freudenreich O, Culhane MA, Olm-Shipman CM, Henderson DC, Schoenfeld DA, Goff DC, Rigotti NA. A double-blind placebo-controlled trial of bupropion sustained-release for smoking cessation in schizophrenia. J Clin Psychopharmacol. 2005 Jun; 25(3):218-25. PMID: 15876899.
    Citations: 52     Fields:    Translation:HumansCTClinical Trials
  113. Henderson DC, Copeland PM, Daley TB, Borba CP, Cather C, Nguyen DD, Louie PM, Evins AE, Freudenreich O, Hayden D, Goff DC. A double-blind, placebo-controlled trial of sibutramine for olanzapine-associated weight gain. Am J Psychiatry. 2005 May; 162(5):954-62. PMID: 15863798.
    Citations: 23     Fields:    Translation:HumansCTClinical Trials
  114. Goff DC, Cather C, Evins AE, Henderson DC, Freudenreich O, Copeland PM, Bierer M, Duckworth K, Sacks FM. Medical morbidity and mortality in schizophrenia: guidelines for psychiatrists. J Clin Psychiatry. 2005 Feb; 66(2):183-94; quiz 147, 273-4. PMID: 15705003.
    Citations: 62     Fields:    Translation:HumansPHPublic Health
  115. Henderson DC, Cagliero E, Copeland PM, Borba CP, Evins AE, Hayden D, Weber MT, Anderson EJ, Allison DB, Daley TB, Schoenfeld D, Goff DC. Glucose metabolism in patients with schizophrenia treated with atypical antipsychotic agents: a frequently sampled intravenous glucose tolerance test and minimal model analysis. Arch Gen Psychiatry. 2005 01; 62(1):19-28. PMID: 15630069.
    Citations: 74     Fields:    Translation:Humans
  116. O'Donnell WJ, Kradin RL, Evins AE, Wittram C. Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 39-2004. A 52-year-old woman with recurrent episodes of atypical pneumonia. N Engl J Med. 2004 Dec 23; 351(26):2741-9. PMID: 15616209.
    Citations: 2     Fields:    Translation:Humans
  117. Goff DC, Herz L, Posever T, Shih V, Tsai G, Henderson DC, Freudenreich O, Evins AE, Yovel I, Zhang H, Schoenfeld D. A six-month, placebo-controlled trial of D-cycloserine co-administered with conventional antipsychotics in schizophrenia patients. Psychopharmacology (Berl). 2005 Apr; 179(1):144-50. PMID: 15502972.
    Citations: 32     Fields:    Translation:HumansCTClinical Trials
  118. Freudenreich O, Cather C, Evins AE, Henderson DC, Goff DC. Attitudes of schizophrenia outpatients toward psychiatric medications: relationship to clinical variables and insight. J Clin Psychiatry. 2004 Oct; 65(10):1372-6. PMID: 15491241.
    Citations: 29     Fields:    Translation:Humans
  119. Goff DC, Bottiglieri T, Arning E, Shih V, Freudenreich O, Evins AE, Henderson DC, Baer L, Coyle J. Folate, homocysteine, and negative symptoms in schizophrenia. Am J Psychiatry. 2004 Sep; 161(9):1705-8. PMID: 15337665.
    Citations: 25     Fields:    Translation:Humans
  120. Evins AE, Cather C, Rigotti NA, Freudenreich O, Henderson DC, Olm-Shipman CM, Goff DC. Two-year follow-up of a smoking cessation trial in patients with schizophrenia: increased rates of smoking cessation and reduction. J Clin Psychiatry. 2004 Mar; 65(3):307-11; quiz 452-3. PMID: 15096068.
    Citations: 24     Fields:    Translation:HumansCTClinical Trials
  121. Fava M, Evins AE, Dorer DJ, Schoenfeld DA. The problem of the placebo response in clinical trials for psychiatric disorders: culprits, possible remedies, and a novel study design approach. Psychother Psychosom. 2003 May-Jun; 72(3):115-27. PMID: 12707478.
    Citations: 58     Fields:    Translation:Humans
  122. Evins AE. Efficacy of newer anticonvulsant medications in bipolar spectrum mood disorders. J Clin Psychiatry. 2003; 64 Suppl 8:9-14. PMID: 12892536.
    Citations: 7     Fields:    Translation:Humans
  123. Evins AE, Amico E, Posever TA, Toker R, Goff DC. D-Cycloserine added to risperidone in patients with primary negative symptoms of schizophrenia. Schizophr Res. 2002 Jul 01; 56(1-2):19-23. PMID: 12084415.
    Citations: 22     Fields:    Translation:HumansCTClinical Trials
  124. Goff DC, Hennen J, Lyoo IK, Tsai G, Wald LL, Evins AE, Yurgelun-Todd DA, Renshaw PF. Modulation of brain and serum glutamatergic concentrations following a switch from conventional neuroleptics to olanzapine. Biol Psychiatry. 2002 Mar 15; 51(6):493-7. PMID: 11922885.
    Citations: 21     Fields:    Translation:Humans
  125. Goff DC, Freudenreich O, Evins AE. Augmentation strategies in the treatment of schizophrenia. CNS Spectr. 2001 Nov; 6(11):904, 907-11. PMID: 15328472.
    Citations: 4     Fields:    
  126. Evins AE, Mays VK, Rigotti NA, Tisdale T, Cather C, Goff DC. A pilot trial of bupropion added to cognitive behavioral therapy for smoking cessation in schizophrenia. Nicotine Tob Res. 2001 Nov; 3(4):397-403. PMID: 11694208.
    Citations: 42     Fields:    Translation:HumansCTClinical Trials
  127. Frankle W, Shera D, Berger-Hershkowitz H, Evins AE, Connolly C, Goff D, Henderson D. Clozapine-associated reduction in arrest rates of psychotic patients with criminal histories. Am J Psychiatry. 2001 02; 158(2):270-4. PMID: 11156810.
    Citations: 5     Fields:    Translation:Humans
  128. Evins AE, Fitzgerald SM, Wine L, Rosselli R, Goff DC. Placebo-controlled trial of glycine added to clozapine in schizophrenia. Am J Psychiatry. 2000 May; 157(5):826-8. PMID: 10784481.
    Citations: 33     Fields:    Translation:HumansCTClinical Trials
  129. Evins AE, Tisdale T. Bupropion and smoking cessation. Am J Psychiatry. 1999 May; 156(5):798-9. PMID: 10327924.
    Citations: 2     Fields:    Translation:Humans
  130. Goff DC, Henderson DC, Evins AE, Amico E. A placebo-controlled crossover trial of D-cycloserine added to clozapine in patients with schizophrenia. Biol Psychiatry. 1999 Feb 15; 45(4):512-4. PMID: 10071726.
    Citations: 33     Fields:    Translation:HumansCTClinical Trials
  131. Goff DC, Evins AE. Negative symptoms in schizophrenia: neurobiological models and treatment response. Harv Rev Psychiatry. 1998 Jul-Aug; 6(2):59-77. PMID: 10370450.
    Citations: 6     Fields:    Translation:Humans
  132. Evins AE, Amico ET, Shih V, Goff DC. Clozapine treatment increases serum glutamate and aspartate compared to conventional neuroleptics. J Neural Transm (Vienna). 1997; 104(6-7):761-6. PMID: 9444574.
    Citations: 15     Fields:    Translation:Humans
  133. Goldring SR, Flannery MS, Petrison KK, Evins AE, Jasty MJ. Evaluation of connective tissue cell responses to orthopaedic implant materials. Connect Tissue Res. 1990; 24(1):77-81. PMID: 2338027.
    Citations:    Fields:    Translation:HumansCells
  134. Milam MG, Evins AE, Sahn SA. Immediate chest roentgenography following fiberoptic bronchoscopy. Chest. 1989 Sep; 96(3):477-9. PMID: 2766807.
    Citations: 1     Fields:    Translation:Humans
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.