Harvard Catalyst Profiles

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Roland Baron, Ph.D., D.D.S.

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Biography
1972 - 1972
Silver Medal, Thesis Prize for the Ph.D. Thesis
1993 - 2003
Merit Award
1997 - 1997
Seymour J, Kreshover Lecture Award
2002 - 2002
Doctor Honoris Causa
2002 - 2002
Japan Society for Promotion of Science Travel Grant
2002 - 2002
Louis V, Avioli Founders Award
2005 - 2005
D. Harold Copp Award in Basic Research

Mentoring
The Role of Insulin of Bone Growth, and the Relation to DeltaFosB/AP1
Summer, 06/20/11 - 08/12/11

Research
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. R01DK112374 (BARON, ROLAND E) Sep 1, 2017 - Jun 30, 2021
    NIH/NIDDK
    PTH resistance and marrow adipogenesis
    Role: Principal Investigator
  2. R01AR064724 (BARON, ROLAND E) May 1, 2014 - Apr 30, 2019
    NIH/NIAMS
    R-Spondin3 as a target for anabolic bone therapy
    Role: Principal Investigator
  3. R01AR062054 (BARON, ROLAND E) Sep 1, 2012 - Aug 31, 2017
    NIH/NIAMS
    Mechanisms and function of the microtubule podosome connection in osteoclasts
    Role: Principal Investigator
  4. R01AG040222 (BARON, ROLAND E) Aug 15, 2011 - Jul 31, 2016
    NIH/NIA
    AP1-dependent regulation of bone mass and energy expenditure in the hypothalamus
    Role: Principal Investigator
  5. R01AR057769 (BARON, ROLAND E) Sep 10, 2010 - Jun 30, 2015
    NIH/NIAMS
    Role of Zfp521 in bone formation and anabolic responses
    Role: Principal Investigator

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Lotinun S, Ishihara Y, Nagano K, Kiviranta R, Carpentier V, Neff L, Parkman V, Ide N, Hu D, Dann P, Brooks D, Bouxsein ML, Wysolmerski J, Gori F, Baron R. Cathepsin K-deficient osteocytes prevent lactation-induced bone loss and parathyroid hormone suppression. J Clin Invest. 2019 May 21; 130. PMID: 31112135.
    Citations:    
  2. Besschetnova T, Brooks DJ, Hu D, Nagano K, Nustad J, Ominsky M, Mitlak B, Hattersley G, Bouxsein ML, Baron R, Lanske B. Abaloparatide improves cortical geometry and trabecular microarchitecture and increases vertebral and femoral neck strength in a rat model of male osteoporosis. Bone. 2019 Jul; 124:148-157. PMID: 31051317.
    Citations:    
  3. Idelevich A, Sato K, Nagano K, Rowe G, Gori F, Baron R. ?FosB Requires Galanin, but not Leptin, to Increase Bone Mass via the Hypothalamus, but both are needed to increase Energy Expenditure. J Bone Miner Res. 2019 Apr 18. PMID: 30998833.
    Citations:    
  4. Addison WN, Hall KC, Kokabu S, Matsubara T, Fu MM, Gori F, Baron R. Zfp423 Regulates Skeletal Muscle Regeneration and Proliferation. Mol Cell Biol. 2019 Apr 15; 39(8). PMID: 30692273.
    Citations:    Fields:    
  5. Piet J, Hu D, Baron R, Shefelbine SJ. Bone adaptation compensates resorption when sciatic neurectomy is followed by low magnitude induced loading. Bone. 2019 Mar; 120:487-494. PMID: 30586636.
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  6. Kim H, Wrann CD, Jedrychowski M, Vidoni S, Kitase Y, Nagano K, Zhou C, Chou J, Parkman VA, Novick SJ, Strutzenberg TS, Pascal BD, Le PT, Brooks DJ, Roche AM, Gerber KK, Mattheis L, Chen W, Tu H, Bouxsein ML, Griffin PR, Baron R, Rosen CJ, Bonewald LF, Spiegelman BM. Irisin Mediates Effects on Bone and Fat via aV Integrin Receptors. Cell. 2018 Dec 13; 175(7):1756-1768.e17. PMID: 30550785.
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  7. Chandler H, Lanske B, Varela A, Guillot M, Boyer M, Brown J, Pierce A, Ominsky M, Mitlak B, Baron R, Kostenuik P, Hattersley G. Abaloparatide, a novel osteoanabolic PTHrP analog, increases cortical and trabecular bone mass and architecture in orchiectomized rats by increasing bone formation without increasing bone resorption. Bone. 2019 Mar; 120:148-155. PMID: 30343166.
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  8. Fulzele K, Dedic C, Lai F, Bouxsein M, Lotinun S, Baron R, Divieti Pajevic P. Loss of Gsa in osteocytes leads to osteopenia due to sclerostin induced suppression of osteoblast activity. Bone. 2018 12; 117:138-148. PMID: 30266511.
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  9. Roca-Ayats N, Ng PY, Garcia-Giralt N, Falcó-Mascaró M, Cozar M, Abril JF, Quesada Gómez JM, Prieto-Alhambra D, Nogués X, Dunford JE, Russell RG, Baron R, Grinberg D, Balcells S, Díez-Pérez A. Functional Characterization of a GGPPS Variant Identified in Atypical Femoral Fracture Patients and Delineation of the Role of GGPPS in Bone-Relevant Cell Types. J Bone Miner Res. 2018 Dec; 33(12):2091-2098. PMID: 30184270.
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  10. Kota SK, Roening C, Patel N, Kota SB, Baron R. PRMT5 inhibition promotes osteogenic differentiation of mesenchymal stromal cells and represses basal interferon stimulated gene expression. Bone. 2018 12; 117:37-46. PMID: 30189247.
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  11. Tsukamoto S, Løvendorf MB, Park J, Salem KZ, Reagan MR, Manier S, Zavidij O, Rahmat M, Huynh D, Takagi S, Kawano Y, Kokubun K, Thrue CA, Nagano K, Petri A, Roccaro AM, Capelletti M, Baron R, Kauppinen S, Ghobrial IM. Inhibition of microRNA-138 enhances bone formation in multiple myeloma bone marrow niche. Leukemia. 2018 08; 32(8):1739-1750. PMID: 29925904.
    Citations:    Fields:    
  12. Idelevich A, Baron R. Brain to bone: What is the contribution of the brain to skeletal homeostasis? Bone. 2018 10; 115:31-42. PMID: 29777919.
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  13. Idelevich A, Sato K, Nagano K, Rowe G, Gori F, Baron R. Neuronal hypothalamic regulation of body metabolism and bone density is galanin dependent. J Clin Invest. 2018 Jun 01; 128(6):2626-2641. PMID: 29596063.
    Citations: 2     Fields:    
  14. Baron R, Gori F. Targeting WNT signaling in the treatment of osteoporosis. Curr Opin Pharmacol. 2018 06; 40:134-141. PMID: 29753194.
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  15. Matsubara T, Kokabu S, Nakatomi C, Kinbara M, Maeda T, Yoshizawa M, Yasuda H, Takano-Yamamoto T, Baron R, Jimi E. The Actin-Binding Protein PPP1r18 Regulates Maturation, Actin Organization, and Bone Resorption Activity of Osteoclasts. Mol Cell Biol. 2018 02 15; 38(4). PMID: 29158294.