Harvard Catalyst Profiles

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William Samuel David, M.D.,PH.D.


Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Lau KHV, David WS, Sadjadi R. Clinical Reasoning: A 15-year-old boy with bilateral wrist pain in the setting of weight loss. Neurology. 2019 Mar 05; 92(10):486-492. PMID: 30833474.
  2. Fridman V, Suriyanarayanan S, Novak P, David W, Macklin EA, McKenna-Yasek D, Walsh K, Aziz-Bose R, Oaklander AL, Brown R, Hornemann T, Eichler F. Randomized trial of l-serine in patients with hereditary sensory and autonomic neuropathy type 1. Neurology. 2019 Jan 22; 92(4):e359-e370. PMID: 30626650.
    Citations:    Fields:    
  3. Shefner JM, Rutkove SB, Caress JB, Benatar M, David WS, Cartwright MC, Macklin EA, Bohorquez JL. Reducing sample size requirements for future ALS clinical trials with a dedicated electrical impedance myography system. Amyotroph Lateral Scler Frontotemporal Degener. 2018 Sep 28; 1-7. PMID: 30265154.
    Citations:    Fields:    
  4. Benatar M, Wuu J, Andersen PM, Atassi N, David W, Cudkowicz M, Schoenfeld D. Randomized, double-blind, placebo-controlled trial of arimoclomol in rapidly progressive SOD1 ALS. Neurology. 2018 Feb 13; 90(7):e565-e574. PMID: 29367439.
    Citations: 3     Fields:    
  5. Bowley MP, David WS, Cho TA, Dighe AS. Case 35-2017. A 57-Year-Old Woman with Hypoesthesia and Weakness in the Legs and Arms. N Engl J Med. 2017 11 16; 377(20):1977-1984. PMID: 29141163.
    Citations: 1     Fields:    Translation:Humans
  6. David WS, Bowley MP, Mehan WA, Shin JH, Gerstner ER, DeWitt JC. Case 19-2017 - A 53-Year-Old Woman with Leg Numbness and Weakness. N Engl J Med. 2017 Jun 22; 376(25):2471-2481. PMID: 28636859.
    Citations:    Fields:    Translation:Humans
  7. Scholz J, Rathmell JP, David WS, Chad DA, Broderick AC, Perros SG, Shin NS, Wells JL, Davis JB, DiMaggio CJ, Wang S, Tate SN. A standardized clinical evaluation of phenotypic diversity in diabetic polyneuropathy. Pain. 2016 10; 157(10):2297-308. PMID: 27322439.
    Citations: 3     Fields:    Translation:Humans
  8. Pasnoor M, He J, Herbelin L, Burns TM, Nations S, Bril V, Wang AK, Elsheikh BH, Kissel JT, Saperstein D, Shaibani JA, Jackson C, Swenson A, Howard JF, Goyal N, David W, Wicklund M, Pulley M, Becker M, Mozaffar T, Benatar M, Pazcuzzi R, Simpson E, Rosenfeld J, Dimachkie MM, Statland JM, Barohn RJ. A randomized controlled trial of methotrexate for patients with generalized myasthenia gravis. Neurology. 2016 Jul 05; 87(1):57-64. PMID: 27306628.
    Citations: 1     Fields:    Translation:Humans
  9. Burns TM, Smith GA, Allen JA, Amato AA, Arnold WD, Barohn R, Benatar M, Bird SJ, Bromberg M, Chahin N, Ciafaloni E, Cohen JA, Corse A, Crum BA, David WS, Dimberg E, Sousa EA, Donofrio PD, Dyck PJ, Engel AG, Ensrud ER, Ferrante M, Freimer M, Gable KL, Gibson S, Gilchrist JM, Goldstein JM, Gooch CL, Goodman BP, Gorelov D, Gospe SM, Goyal NA, Guidon AC, Guptill JT, Gutmann L, Gutmann L, Gwathmey K, Harati Y, Harper CM, Hehir MK, Hobson-Webb LD, Howard JF, Jackson CE, Johnson N, Jones SM, Juel VC, Kaminski HJ, Karam C, Kennelly KD, Khella S, Khoury J, Kincaid JC, Kissel JT, Kolb N, Lacomis D, Ladha S, Larriviere D, Lewis RA, Li Y, Litchy WJ, Logigian E, Lou JS, MacGowen DJ, Maselli R, Massey JM, Mauermann ML, Mathews KD, Meriggioli MN, Miller RG, Moon JS, Mozaffar T, Nations SP, Nowak RJ, Ostrow LW, Pascuzzi RM, Peltier A, Ruzhansky K, Richman DP, Ross MA, Rubin DI, Russell JA, Sachs GM, Salajegheh MK, Saperstein DS, Scelsa S, Selcen D, Shaibani A, Shieh PB, Silvestri NJ, Singleton JR, Smith BE, So YT, Solorzano G, Sorenson EJ, Srinivasen J, Tavee J, Tawil R, Thaisetthawatkul P, Thornton C, Trivedi J, Vernino S, Wang AK, Webb TA, Weiss MD, Windebank AJ, Wolfe GI. Editorial by concerned physicians: Unintended effect of the orphan drug act on the potential cost of 3,4-diaminopyridine. Muscle Nerve. 2016 Feb; 53(2):165-8. PMID: 26662952.
    Citations: 1     Fields:    Translation:Humans
  10. David WS, Chad DA. Neuromuscular Disorders. Semin Neurol. 2015 Aug; 35(4):325. PMID: 26502756.
    Citations:    Fields:    Translation:Humans
  11. Narayanaswami P, Dubinsky R, Wang D, Gjorvad G, David W, Finder J, Smith B, Cheng J, Shapiro F, Mellion M, Spurney C, Wolff J, England J. Quality improvement in neurology: muscular dystrophy quality measures. Neurology. 2015 Sep 08; 85(10):905-9. PMID: 26333798; PMCID: PMC4560061.
    Citations: 2     Fields:    Translation:Humans
  12. David WS. Case 3-2015: A woman with abdominal pain, dyspnea, and diplopia. N Engl J Med. 2015 04 23; 372(17):1675. PMID: 25901441.
    Citations:    Fields:    Translation:Humans
  13. Fridman V, Oaklander AL, David WS, Johnson EA, Pan J, Novak P, Brown RH, Eichler FS. Natural history and biomarkers in hereditary sensory neuropathy type 1. Muscle Nerve. 2015 Apr; 51(4):489-95. PMID: 25042817.
    Citations: 4     Fields:    Translation:Humans
  14. David WS, Temin ES, Kraeft JJ, Hooper DC. Case records of the Massachusetts General Hospital. Case 3-2015. A 60-year-old woman with abdominal pain, dyspnea, and diplopia. N Engl J Med. 2015 Jan 22; 372(4):364-72. PMID: 25607430.
    Citations:    Fields:    Translation:Humans
  15. Amato AA, Sivakumar K, Goyal N, David WS, Salajegheh M, Praestgaard J, Lach-Trifilieff E, Trendelenburg AU, Laurent D, Glass DJ, Roubenoff R, Tseng BS, Greenberg SA. Treatment of sporadic inclusion body myositis with bimagrumab. Neurology. 2014 Dec 09; 83(24):2239-46. PMID: 25381300; PMCID: PMC4277670.
    Citations: 33     Fields:    Translation:HumansCells
  16. Narayanaswami P, Weiss M, Selcen D, David W, Raynor E, Carter G, Wicklund M, Barohn RJ, Ensrud E, Griggs RC, Gronseth G, Amato AA. Evidence-based guideline summary: diagnosis and treatment of limb-girdle and distal dystrophies: report of the guideline development subcommittee of the American Academy of Neurology and the practice issues review panel of the American Association of Neuromuscular & Electrodiagnostic Medicine. Neurology. 2014 Oct 14; 83(16):1453-63. PMID: 25313375; PMCID: PMC4206155.
    Citations: 29     Fields:    Translation:Humans
  17. Zhao Y, Cudkowicz ME, Shefner JM, Krivickas L, David WS, Vriesendorp F, Pestronk A, Caress JB, Katz J, Simpson E, Rosenfeld J, Pascuzzi R, Glass J, Rezania K, Harmatz JS, Schoenfeld D, Greenblatt DJ. Systemic pharmacokinetics and cerebrospinal fluid uptake of intravenous ceftriaxone in patients with amyotrophic lateral sclerosis. J Clin Pharmacol. 2014 Oct; 54(10):1180-7. PMID: 24771634.
    Citations: 4     Fields:    Translation:Humans
  18. England JD, Franklin G, Gjorvad G, Swain-Eng R, Brannagan TH, David WS, Dubinsky RM, Smith BE. Quality improvement in neurology: Distal symmetric polyneuropathy quality measures. Neurology. 2014 May 13; 82(19):1745-8. PMID: 24696504; PMCID: PMC4032209.
    Citations: 4     Fields:    Translation:Humans
  19. Rutkove SB, Caress JB, Cartwright MS, Burns TM, Warder J, David WS, Goyal N, Maragakis NJ, Benatar M, Sharma KR, Narayanaswami P, Raynor EM, Watson ML, Shefner JM. Electrical impedance myography correlates with standard measures of ALS severity. Muscle Nerve. 2014 Mar; 49(3):441-3. PMID: 24273034.
    Citations: 22     Fields:    Translation:Humans
  20. Berry JD, Shefner JM, Conwit R, Schoenfeld D, Keroack M, Felsenstein D, Krivickas L, David WS, Vriesendorp F, Pestronk A, Caress JB, Katz J, Simpson E, Rosenfeld J, Pascuzzi R, Glass J, Rezania K, Rothstein JD, Greenblatt DJ, Cudkowicz ME. Design and initial results of a multi-phase randomized trial of ceftriaxone in amyotrophic lateral sclerosis. PLoS One. 2013; 8(4):e61177. PMID: 23613806; PMCID: PMC3629222.
    Citations: 28     Fields:    Translation:HumansCTClinical Trials
  21. Karam C, Quinn CC, Paganoni S, David WS. Teaching NeuroImages: Ganglion cyst causing pure sensory ulnar neuropathy at the wrist. Neurology. 2012 Aug 21; 79(8):e76. PMID: 22915183.
    Citations:    Fields:    Translation:Humans
  22. Rutkove SB, Caress JB, Cartwright MS, Burns TM, Warder J, David WS, Goyal N, Maragakis NJ, Clawson L, Benatar M, Usher S, Sharma KR, Gautam S, Narayanaswami P, Raynor EM, Watson ML, Shefner JM. Electrical impedance myography as a biomarker to assess ALS progression. Amyotroph Lateral Scler. 2012 Sep; 13(5):439-45. PMID: 22670883; PMCID: PMC3422377.
    Citations: 45     Fields:    Translation:Humans
  23. Fridman V, David WS. Electrodiagnostic evaluation of lower extremity mononeuropathies. Neurol Clin. 2012 May; 30(2):505-28. PMID: 22361372.
    Citations: 1     Fields:    Translation:Humans
  24. David WS, Chad DA, Kambadakone A, Hedley-Whyte ET. Case records of the Massachusetts General Hospital. Case 7-2012. A 79-year-old man with pain and weakness in the legs. N Engl J Med. 2012 Mar 08; 366(10):944-54. PMID: 22397657.
    Citations: 1     Fields:    Translation:Humans
  25. Saboisky JP, Stashuk DW, Hamilton-Wright A, Carusona AL, Campana LM, Trinder J, Eckert DJ, Jordan AS, McSharry DG, White DP, Nandedkar S, David WS, Malhotra A. Neurogenic changes in the upper airway of patients with obstructive sleep apnea. Am J Respir Crit Care Med. 2012 Feb 01; 185(3):322-9. PMID: 22016445; PMCID: PMC3297112.
    Citations: 21     Fields:    Translation:HumansCells
  26. Shefner JM, Watson ML, Simionescu L, Caress JB, Burns TM, Maragakis NJ, Benatar M, David WS, Sharma KR, Rutkove SB. Multipoint incremental motor unit number estimation as an outcome measure in ALS. Neurology. 2011 Jul 19; 77(3):235-41. PMID: 21676915; PMCID: PMC3136054.
    Citations: 28     Fields:    Translation:HumansCells
  27. David WS, Goyal N, Henry FP, Baldassari LE, Redmond RW. Validation of an incremental motor unit number estimation technique in rabbits. Muscle Nerve. 2010 Jun; 41(6):794-9. PMID: 20169589.
    Citations: 3     Fields:    Translation:HumansAnimalsCells
  28. Goyal N, Salameh JS, Baldassari LE, David WS. Added sampling improves reproducibility of multipoint motor unit estimates. Muscle Nerve. 2010 Jan; 41(1):114-6. PMID: 19813198.
    Citations: 1     Fields:    Translation:HumansCells
  29. Salameh JS, Atassi N, David WS. SOD1 (A4V)-mediated ALS presenting with lower motor neuron facial diplegia and unilateral vocal cord paralysis. Muscle Nerve. 2009 Nov; 40(5):880-2. PMID: 19618436.
    Citations:    Fields:    Translation:Humans
  30. Salameh JS, Shenoy AM, David WS. Novel SPG3A and SPG4 mutations in two patients with Silver syndrome. J Clin Neuromuscul Dis. 2009 Sep; 11(1):57-9. PMID: 19730024.
    Citations:    Fields:    Translation:HumansCells
  31. Henry FP, Goyal NA, David WS, Wes D, Bujold KE, Randolph MA, Winograd JM, Kochevar IE, Redmond RW. Improving electrophysiologic and histologic outcomes by photochemically sealing amnion to the peripheral nerve repair site. Surgery. 2009 Mar; 145(3):313-21. PMID: 19231584.
    Citations: 7     Fields:    Translation:HumansAnimals
  32. Sorenson EJ, Windbank AJ, Mandrekar JN, Bamlet WR, Appel SH, Armon C, Barkhaus PE, Bosch P, Boylan K, David WS, Feldman E, Glass J, Gutmann L, Katz J, King W, Luciano CA, McCluskey LF, Nash S, Newman DS, Pascuzzi RM, Pioro E, Sams LJ, Scelsa S, Simpson EP, Subramony SH, Tiryaki E, Thornton CA. Subcutaneous IGF-1 is not beneficial in 2-year ALS trial. Neurology. 2008 Nov 25; 71(22):1770-5. PMID: 19029516; PMCID: PMC2617770.
    Citations: 60     Fields:    Translation:HumansCTClinical Trials
  33. Kesler SM, Sprenkle MD, David WS, Leatherman JW. Severe weakness complicating status asthmaticus despite minimal duration of neuromuscular paralysis. Intensive Care Med. 2009 Jan; 35(1):157-60. PMID: 18807012.
    Citations: 3     Fields:    Translation:Humans
  34. Simmons Z, Felgoise SH, Bremer BA, Walsh SM, Hufford DJ, Bromberg MB, David W, Forshew DA, Heiman-Patterson TD, Lai EC, McCluskey L. The ALSSQOL: balancing physical and nonphysical factors in assessing quality of life in ALS. Neurology. 2006 Nov 14; 67(9):1659-64. PMID: 17101900.
    Citations: 19     Fields:    Translation:Humans
  35. Lange DJ, Lechtzin N, Davey C, David W, Heiman-Patterson T, Gelinas D, Becker B, Mitsumoto H. High-frequency chest wall oscillation in ALS: an exploratory randomized, controlled trial. Neurology. 2006 Sep 26; 67(6):991-7. PMID: 17000967.
    Citations: 3     Fields:    Translation:HumansCTClinical Trials
  36. Kang PB, Lidov HG, David WS, Torres A, Anthony DC, Jones HR, Darras BT. Diagnostic value of electromyography and muscle biopsy in arthrogryposis multiplex congenita. Ann Neurol. 2003 Dec; 54(6):790-5. PMID: 14681888.
    Citations: 1     Fields:    Translation:Humans
  37. Cudkowicz ME, Shefner JM, Schoenfeld DA, Brown RH, Johnson H, Qureshi M, Jacobs M, Rothstein JD, Appel SH, Pascuzzi RM, Heiman-Patterson TD, Donofrio PD, David WS, Russell JA, Tandan R, Pioro EP, Felice KJ, Rosenfeld J, Mandler RN, Sachs GM, Bradley WG, Raynor EM, Baquis GD, Belsh JM, Novella S, Goldstein J, Hulihan J. A randomized, placebo-controlled trial of topiramate in amyotrophic lateral sclerosis. Neurology. 2003 Aug 26; 61(4):456-64. PMID: 12939417.
    Citations: 41     Fields:    Translation:HumansCTClinical Trials
  38. David WS, Chaudhry V, Dubin AH, Shields RW. Literature review: nervepace digital electroneurometer in the diagnosis of carpal tunnel syndrome. Muscle Nerve. 2003 Mar; 27(3):378-85. PMID: 12635127.
    Citations:    Fields:    Translation:Humans
  39. David WS. Myoglobinuria. Neurol Clin. 2000 Feb; 18(1):215-43. PMID: 10658177.
    Citations: 14     Fields:    Translation:Humans
  40. David WS, Mahdavi Z, Nance M, Khan M. Hyperlipidemia and neuropathy. Electromyogr Clin Neurophysiol. 1999 Jun; 39(4):227-30. PMID: 10394507.
    Citations: 2     Fields:    Translation:HumansCells
  41. David WS, Roehr CL, Leatherman JW. EMG findings in acute myopathy with status asthmaticus, steroids and paralytics. Clinical and electrophysiologic correlation. Electromyogr Clin Neurophysiol. 1998 Sep; 38(6):371-6. PMID: 9783124.
    Citations: 5     Fields:    Translation:Humans
  42. David WS, Sharif AA. Clozapine-induced myokymia. Muscle Nerve. 1998 Jun; 21(6):827-8. PMID: 9585344.
    Citations:    Fields:    Translation:Humans
  43. Nance MA, Raabe WA, Midani H, Kolodny EH, David WS, Megna L, Pericak-Vance MA, Haines JL. Clinical heterogeneity of familial spastic paraplegia linked to chromosome 2p21. Hum Hered. 1998 May-Jun; 48(3):169-78. PMID: 9618065.
    Citations: 2     Fields:    Translation:HumansCells
  44. David WS, Bundlie SR, Mahdavi Z. Polysomnographic studies in amyotrophic lateral sclerosis. J Neurol Sci. 1997 Oct; 152 Suppl 1:S29-35. PMID: 9419051.
    Citations: 9     Fields:    Translation:HumansCTClinical Trials
  45. David WS, Doyle JJ. Acute infantile weakness: a case of vaccine-associated poliomyelitis. Muscle Nerve. 1997 Jun; 20(6):747-9. PMID: 9149084.
    Citations:    Fields:    Translation:Humans
  46. David WS, Peine C, Schlesinger P, Smith SA. Nonsystemic vasculitic mononeuropathy multiplex, cryoglobulinemia, and hepatitis C. Muscle Nerve. 1996 Dec; 19(12):1596-602. PMID: 8941274.
    Citations: 3     Fields:    Translation:Humans
  47. Roth CR, Glaze LE, Goding GS, David WS. Spasmodic dysphonia symptoms as initial presentation of amyotrophic lateral sclerosis. J Voice. 1996 Dec; 10(4):362-7. PMID: 8943140.
    Citations: 1     Fields:    Translation:Humans
  48. Leatherman JW, Fluegel WL, David WS, Davies SF, Iber C. Muscle weakness in mechanically ventilated patients with severe asthma. Am J Respir Crit Care Med. 1996 May; 153(5):1686-90. PMID: 8630621.
    Citations: 32     Fields:    Translation:Humans
  49. David WS, Jones HR. Soft tissue sarcoma presenting as atypical extremity pain. Muscle Nerve. 1994 Sep; 17(9):1071-2. PMID: 8065397.
    Citations:    Fields:    Translation:Humans
  50. David WS, Jones HR. Electromyography and biopsy correlation with suggested protocol for evaluation of the floppy infant. Muscle Nerve. 1994 Apr; 17(4):424-30. PMID: 8170489.
    Citations: 2     Fields:    Translation:Humans
  51. Doyle JJ, David WS. Posterior antebrachial cutaneous neuropathy associated with lateral elbow pain. Muscle Nerve. 1993 Dec; 16(12):1417-8. PMID: 8232403.
    Citations:    Fields:    Translation:Humans
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Funded by the NIH/NCATS Clinical and Translational Science Award (CTSA) program, grant number UL1TR001102, and through institutional support from Harvard University, Harvard Medical School, Harvard T.H. Chan School of Public Health, Beth Israel Deaconess Medical Center, Boston Children's Hospital, Brigham and Women's Hospital, Massachusetts General Hospital and the Dana Farber Cancer Institute.